LiteFold/GO huggingface dataset:
chromosome passenger complex localization to spindle midzone (GO:0035853)
Namespace: biological_process
Definition: A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
Synonyms: chromosomal passenger complex localization to spindle midzone; chromosome passenger complex localisation to spindle midzone; chromosome passenger complex localization to central spindle; chromosome passenger complex localization to spindle equator; CPC complex localization to spindle midzone; CPC localization to spindle midzone
megakaryocyte development (GO:0035855)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
Synonyms: megakaryocyte cell development
eosinophil fate specification (GO:0035857)
Namespace: biological_process
Definition: The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
Synonyms: eosinophil cell fate specification
eosinophil fate determination (GO:0035858)
Namespace: biological_process
Definition: The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Synonyms: eosinophil cell fate determination
glial cell-derived neurotrophic factor receptor signaling pathway (GO:0035860)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to a glial cell-derived neurotrophic factor receptor.
Synonyms: GDNF receptor signaling pathway; glial cell derived neurotrophic factor receptor signaling pathway; glial cell line-derived neurotrophic factor receptor signalling pathway; glial cell-derived neurotrophic factor receptor signalling pathway
site of double-strand break (GO:0035861)
Namespace: cellular_component
Definition: A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
Synonyms: DNA damage foci; DNA damage focus; ionizing radiation-induced foci; IRIF; site of DSB
dITP catabolic process (GO:0035863)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
Synonyms: 2'-Deoxyinosine 5'-triphosphate catabolic process; 2'-Deoxyinosine-5'-triphosphate catabolic process; deoxyinosine 5'-triphosphate catabolic process; deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate) catabolic process; dITP breakdown; dITP catabolism; dITP degradation
response to potassium ion (GO:0035864)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
Synonyms: response to K+ ion; response to potassium
cellular response to potassium ion (GO:0035865)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
Synonyms: cellular response to K+ ion; cellular response to potassium
alphav-beta3 integrin-PKCalpha complex (GO:0035866)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.
Synonyms: alphav-beta3 integrin-PKCa complex; alphav-beta3 integrin-protein kinase C alpha complex
alphav-beta3 integrin-IGF-1-IGF1R complex (GO:0035867)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.
alphav-beta3 integrin-HMGB1 complex (GO:0035868)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.
Synonyms: alphav-beta3 integrin-high mobility group box 1 complex
ciliary transition zone (GO:0035869)
Namespace: cellular_component
Definition: A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
Synonyms: cilial transition zone; cilium transition zone; connecting cilium
Comment: Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone.
dITP diphosphatase activity (GO:0035870)
Namespace: molecular_function
Definition: Catalysis of the reaction: dITP + H2O = dIMP + H+ + diphosphate.
Synonyms: 2'-deoxyinosine-5'-triphosphate pyrophosphohydrolase activity; deoxyinosine triphosphate pyrophosphatase activity; dITP pyrophosphatase activity
protein K11-linked deubiquitination (GO:0035871)
Namespace: biological_process
Definition: A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
Synonyms: protein K11-linked deubiquitinylation; protein K11-linked deubiquitylation
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number.
Synonyms: NLR signaling pathway; NOD-like receptor signaling pathway; nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway; nucleotide-binding domain, leucine rich repeat containing receptor signal transduction; nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway; nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway
lactate transmembrane transport (GO:0035873)
Namespace: biological_process
Definition: The process in which lactate is transported across a membrane. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
Synonyms: lactate membrane transport
Comment: Note that this term is not intended for use in annotating lateral movement within membranes.
cellular response to copper ion starvation (GO:0035874)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
Synonyms: cellular response to copper starvation
maintenance of meiotic sister chromatid cohesion, centromeric (GO:0035875)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
Synonyms: maintenance of centromeric meiotic sister chromatin cohesion; maintenance of meiotic sister chromatin cohesion at centromere; maintenance of sister chromatin cohesion at centromere at meiosis I
obsolete maintenance of meiotic sister chromatid cohesion, arms (GO:0035876)
Namespace: biological_process
Definition: OBSOLETE. The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
Synonyms: maintenance of meiotic sister chromatin cohesion along arms; maintenance of sister chromatin cohesion along arms at meiosis I
Comment: This term was added in error
death effector domain binding (GO:0035877)
Namespace: molecular_function
Definition: Binding to a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).
Synonyms: DED binding
Comment: For binding to the death domain, consider instead the term 'death domain binding ; GO:0070513'.
nail development (GO:0035878)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.
plasma membrane lactate transport (GO:0035879)
Namespace: biological_process
Definition: The directed movement of lactate across a plasma membrane.
Synonyms: lactate plasma membrane transport
embryonic nail plate morphogenesis (GO:0035880)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
amacrine cell differentiation (GO:0035881)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
Synonyms: amacrine neuron differentiation
defecation rhythm (GO:0035882)
Namespace: biological_process
Definition: The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.
Synonyms: defecation behavior; defecation cycle; defecation motor program; DMP
enteroendocrine cell differentiation (GO:0035883)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.
arabinan biosynthetic process (GO:0035884)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.
exochitinase activity (GO:0035885)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.
vascular associated smooth muscle cell differentiation (GO:0035886)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
Synonyms: vascular smooth muscle cell differentiation; VSMC differentiation
aortic smooth muscle cell differentiation (GO:0035887)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.
isoguanine deaminase activity (GO:0035888)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + H2O + isoguanine = NH4+ + xanthine.
Synonyms: 2-hydroxyadenine deaminase activity; 2-oxoadenine deaminase activity
otolith tethering (GO:0035889)
Namespace: biological_process
Definition: The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.
obsolete perturbation of platelet aggregation in another organism (GO:0035892)
Namespace: biological_process
Definition: OBSOLETE. The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
Synonyms: modulation by organism of platelet aggregation in other organism; modulation of platelet aggregation in another organism; modulation of platelet aggregation in other organism; regulation of platelet aggregation in other organism
Comment: This term was obsoleted because it is too general.
obsolete suppression of platelet aggregation in another organism (GO:0035893)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.
Synonyms: disruption of platelet aggregation in other organism; down-regulation of platelet aggregation in other organism; downregulation of platelet aggregation in other organism; inhibition of platelet aggregation in other organism; negative regulation of platelet aggregation in another organism; negative regulation of platelet aggregation in other organism
Comment: This term was obsoleted because it does not describe whether this is symbiont- or venom-mediated.
obsolete induction of platelet aggregation in another organism (GO:0035894)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.
Synonyms: positive regulation of platelet aggregation in another organism; positive regulation of platelet aggregation in other organism; up-regulation of platelet aggregation in other organism; upregulation of platelet aggregation in other organism
Comment: This term was obsoleted because it did not specify the more of interaction between organisms. Consider venom-mediated platelet aggregation ; GO:0044478.
obsolete modulation of mast cell degranulation in another organism (GO:0035895)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
Synonyms: modulation of mast cell degranulation in other organism; regulation of mast cell degranulation in other organism
Comment: This term was obsoleted because it is too general.
obsolete positive regulation of mast cell degranulation in another organism (GO:0035896)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.
Synonyms: positive regulation of mast cell degranulation in other organism; up-regulation of mast cell degranulation in other organism; upregulation of mast cell degranulation in other organism
Comment: This term was obsoleted because it is too general.
obsolete proteolysis in other organism (GO:0035897)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.
Comment: This term was obsoleted because it represents a molecular function.
parathyroid hormone secretion (GO:0035898)
Namespace: biological_process
Definition: The regulated release of parathyroid hormone into the circulatory system.
Synonyms: parathormone secretion; parathyrin secretion; PTH secretion
obsolete suppression of blood coagulation in another organism (GO:0035899)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
Synonyms: disruption of blood coagulation in other organism; down-regulation of blood coagulation in other organism; downregulation of blood coagulation in other organism; inhibition of blood coagulation in other organism; negative regulation of blood clotting in other organism; negative regulation of blood coagulation in another organism; negative regulation of blood coagulation in other organism; suppression of blood clotting in another organism
Comment: This term was obsoleted because it does not describe whether this is symbiont- or venom-mediated.
response to isolation stress (GO:0035900)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
Synonyms: response to social isolation
obsolete cellular response to isolation stress (GO:0035901)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
Synonyms: cellular response to social isolation
Comment: This term was obsoleted because it represents the molecular activities involved in response to isolation stress ; GO:0035900.
cellular response to immobilization stress (GO:0035903)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
Synonyms: cellular response to immobilisation stress; cellular response to restraint stress
aorta development (GO:0035904)
Namespace: biological_process
Definition: The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.
ascending aorta development (GO:0035905)
Namespace: biological_process
Definition: The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
descending aorta development (GO:0035906)
Namespace: biological_process
Definition: The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
dorsal aorta development (GO:0035907)
Namespace: biological_process
Definition: The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
ventral aorta development (GO:0035908)
Namespace: biological_process
Definition: The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
aorta morphogenesis (GO:0035909)
Namespace: biological_process
Definition: The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
ascending aorta morphogenesis (GO:0035910)
Namespace: biological_process
Definition: The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
descending aorta morphogenesis (GO:0035911)
Namespace: biological_process
Definition: The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
dorsal aorta morphogenesis (GO:0035912)
Namespace: biological_process
Definition: The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
ventral aorta morphogenesis (GO:0035913)
Namespace: biological_process
Definition: The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
skeletal muscle cell differentiation (GO:0035914)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.