LiteFold/GO huggingface dataset:
positive regulation of nervous system process (GO:0031646)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
Synonyms: activation of neurological process; positive regulation of neurological process; positive regulation of neurological system process; positive regulation of neurophysiological process; stimulation of neurological process; up regulation of neurological process; up-regulation of neurological process; upregulation of neurological process
regulation of protein stability (GO:0031647)
Namespace: biological_process
Definition: Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
protein destabilization (GO:0031648)
Namespace: biological_process
Definition: Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
Synonyms: negative regulation of protein stability; protein destabilisation
heat generation (GO:0031649)
Namespace: biological_process
Definition: Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
regulation of heat generation (GO:0031650)
Namespace: biological_process
Definition: Any process that modulates the rate or extent of heat generation.
negative regulation of heat generation (GO:0031651)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate or extent of heat generation.
Synonyms: down regulation of heat generation; down-regulation of heat generation; downregulation of heat generation; inhibition of heat generation
positive regulation of heat generation (GO:0031652)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of heat generation.
Synonyms: activation of heat generation; stimulation of heat generation; up regulation of heat generation; up-regulation of heat generation; upregulation of heat generation
heat dissipation (GO:0031653)
Namespace: biological_process
Definition: Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.
regulation of heat dissipation (GO:0031654)
Namespace: biological_process
Definition: Any process that modulates the rate or extent of heat dissipation.
negative regulation of heat dissipation (GO:0031655)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate or extent of heat dissipation.
Synonyms: down regulation of heat dissipation; down-regulation of heat dissipation; downregulation of heat dissipation; inhibition of heat dissipation
positive regulation of heat dissipation (GO:0031656)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of heat dissipation.
Synonyms: activation of heat dissipation; stimulation of heat dissipation; up regulation of heat dissipation; up-regulation of heat dissipation; upregulation of heat dissipation
obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031657)
Namespace: biological_process
Definition: OBSOLETE. Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
Synonyms: G1/S-specific regulation of cyclin-dependent protein kinase activity; regulation of cyclin-dependent protein kinase activity during G1/S; regulation of cyclin-dependent protein kinase activity involved in G1/S
Comment: The term has been obsoleted because it represents a GO-CAM model.
obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031658)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
Synonyms: G1/S-specific down regulation of cyclin-dependent protein kinase activity; G1/S-specific down-regulation of cyclin-dependent protein kinase activity; G1/S-specific downregulation of cyclin-dependent protein kinase activity; G1/S-specific inhibition of cyclin-dependent protein kinase activity; G1/S-specific negative regulation of cyclin-dependent protein kinase activity; negative regulation of cyclin-dependent protein kinase activity during G1/S; negative regulation of cyclin-dependent protein kinase activity involved in G1/S
Comment: The term has been obsoleted because it represents a GO-CAM model.
obsolete positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle (GO:0031659)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
Synonyms: G1/S-specific activation of cyclin-dependent protein kinase activity; G1/S-specific positive regulation of cyclin-dependent protein kinase activity; G1/S-specific stimulation of cyclin-dependent protein kinase activity; G1/S-specific up regulation of cyclin-dependent protein kinase activity; G1/S-specific up-regulation of cyclin-dependent protein kinase activity; G1/S-specific upregulation of cyclin-dependent protein kinase activity; positive regulation of cyclin-dependent protein kinase activity during G1/S; positive regulation of cyclin-dependent protein kinase activity involved in G1/S
Comment: The term has been obsoleted because it represents a GO-CAM model.
obsolete regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle (GO:0031660)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.
Synonyms: G2/M-specific regulation of cyclin-dependent protein kinase activity; regulation of cyclin-dependent protein kinase activity during G2/M; regulation of cyclin-dependent protein kinase activity involved in G2/M
Comment: This term was obsoleted because it is a MF represented as a BP.
obsolete negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle (GO:0031661)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.
Synonyms: G2/M-specific down regulation of cyclin-dependent protein kinase activity; G2/M-specific down-regulation of cyclin-dependent protein kinase activity; G2/M-specific downregulation of cyclin-dependent protein kinase activity; G2/M-specific inhibition of cyclin-dependent protein kinase activity; G2/M-specific negative regulation of cyclin-dependent protein kinase activity; negative regulation of cyclin-dependent protein kinase activity during G2/M; negative regulation of cyclin-dependent protein kinase activity involved in G2/M
Comment: This term was obsoleted because it is a MF represented as a BP.
lipopolysaccharide-mediated signaling pathway (GO:0031663)
Namespace: biological_process
Definition: The series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
Synonyms: lipopolysaccharide-mediated signalling pathway; LPS-mediated signaling pathway
regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
Synonyms: regulation of lipopolysaccharide-mediated signalling pathway; regulation of LPS-mediated signaling pathway
negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
Synonyms: down regulation of lipopolysaccharide-mediated signaling pathway; down-regulation of lipopolysaccharide-mediated signaling pathway; downregulation of lipopolysaccharide-mediated signaling pathway; inhibition of lipopolysaccharide-mediated signaling pathway; negative regulation of lipopolysaccharide-mediated signalling pathway; negative regulation of LPS-mediated signaling pathway
positive regulation of lipopolysaccharide-mediated signaling pathway (GO:0031666)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
Synonyms: activation of lipopolysaccharide-mediated signaling pathway; positive regulation of lipopolysaccharide-mediated signalling pathway; positive regulation of LPS-mediated signaling pathway; stimulation of lipopolysaccharide-mediated signaling pathway; up regulation of lipopolysaccharide-mediated signaling pathway; up-regulation of lipopolysaccharide-mediated signaling pathway; upregulation of lipopolysaccharide-mediated signaling pathway
obsolete cellular response to extracellular stimulus (GO:0031668)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
Comment: The reason for obsoletion is that this term is too vague.
cellular response to nutrient levels (GO:0031669)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
primary cell septum biogenesis (GO:0031671)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.
A band (GO:0031672)
Namespace: cellular_component
Definition: The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
Synonyms: A disc; anisotropic disc; Q disc; transverse disc
H zone (GO:0031673)
Namespace: cellular_component
Definition: A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.
Synonyms: H band; H disc
I band (GO:0031674)
Namespace: cellular_component
Definition: A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
Synonyms: I disc; isotropic disc; J disc
plasma membrane-derived thylakoid membrane (GO:0031676)
Namespace: cellular_component
Definition: The pigmented membrane of a plasma membrane-derived thylakoid.
Synonyms: plasma membrane thylakoid membrane
obsolete NADH dehydrogenase (plastoquinone) activity (GO:0031679)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.
Synonyms: NADH:plastoquinone reductase activity
Comment: The reason for obsoletion is that this term is equivalent to NADPH dehydrogenase (quinone) activity ; GO:0008753.
G-protein beta-subunit binding (GO:0031681)
Namespace: molecular_function
Definition: Binding to a G-protein beta subunit.
Synonyms: G-beta protein subunit binding
G-protein gamma-subunit binding (GO:0031682)
Namespace: molecular_function
Definition: Binding to a G-protein gamma subunit.
Synonyms: G-gamma protein subunit binding
G-protein beta/gamma-subunit complex binding (GO:0031683)
Namespace: molecular_function
Definition: Binding to a complex of G-protein beta/gamma subunits.
obsolete heterotrimeric G-protein complex cycle (GO:0031684)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.
Comment: The reason for obsoleting is that it is an arbitrary grouping term that groups the molecular functions required for the G-protein complex cycle, and this is not a bona fide biological process.
A1 adenosine receptor binding (GO:0031686)
Namespace: molecular_function
Definition: Binding to an A1 adenosine receptor.
Synonyms: A1 adenosine receptor ligand
A2A adenosine receptor binding (GO:0031687)
Namespace: molecular_function
Definition: Binding to an A2A adenosine receptor.
Synonyms: A2A adenosine receptor ligand
A2B adenosine receptor binding (GO:0031688)
Namespace: molecular_function
Definition: Binding to an A2B adenosine receptor.
Synonyms: A2B adenosine receptor ligand
A3 adenosine receptor binding (GO:0031689)
Namespace: molecular_function
Definition: Binding to an A3 adenosine receptor.
Synonyms: A3 adenosine receptor ligand
adrenergic receptor binding (GO:0031690)
Namespace: molecular_function
Definition: Binding to an adrenergic receptor.
Synonyms: adrenergic receptor ligand
alpha-1A adrenergic receptor binding (GO:0031691)
Namespace: molecular_function
Definition: Binding to an alpha-1A adrenergic receptor.
Synonyms: alpha-1A adrenergic receptor ligand
alpha-1D adrenergic receptor binding (GO:0031693)
Namespace: molecular_function
Definition: Binding to an alpha-1D adrenergic receptor.
Synonyms: alpha-1D adrenergic receptor ligand
alpha-2A adrenergic receptor binding (GO:0031694)
Namespace: molecular_function
Definition: Binding to an alpha-2A adrenergic receptor.
Synonyms: alpha-2A adrenergic receptor ligand
alpha-2B adrenergic receptor binding (GO:0031695)
Namespace: molecular_function
Definition: Binding to an alpha-2B adrenergic receptor.
Synonyms: alpha-2B adrenergic receptor ligand
alpha-2C adrenergic receptor binding (GO:0031696)
Namespace: molecular_function
Definition: Binding to an alpha-2C adrenergic receptor.
Synonyms: alpha-2C adrenergic receptor ligand
beta-1 adrenergic receptor binding (GO:0031697)
Namespace: molecular_function
Definition: Binding to a beta-1 adrenergic receptor.
Synonyms: beta-1 adrenergic receptor ligand
beta-2 adrenergic receptor binding (GO:0031698)
Namespace: molecular_function
Definition: Binding to a beta-2 adrenergic receptor.
Synonyms: beta-2 adrenergic receptor ligand
beta-3 adrenergic receptor binding (GO:0031699)
Namespace: molecular_function
Definition: Binding to a beta-3 adrenergic receptor.
Synonyms: beta-3 adrenergic receptor ligand
adrenomedullin receptor binding (GO:0031700)
Namespace: molecular_function
Definition: Binding to an adrenomedullin receptor.
Synonyms: adrenomedullin receptor ligand
angiotensin receptor binding (GO:0031701)
Namespace: molecular_function
Definition: Binding to an angiotensin receptor.
Synonyms: angiotensin receptor ligand
type 1 angiotensin receptor binding (GO:0031702)
Namespace: molecular_function
Definition: Binding to a type 1 angiotensin receptor.
Synonyms: AT1 receptor binding; type 1 angiotensin receptor ligand
type 2 angiotensin receptor binding (GO:0031703)
Namespace: molecular_function
Definition: Binding to a type 2 angiotensin receptor.
Synonyms: AT2 receptor binding; type 2 angiotensin receptor ligand
bombesin receptor binding (GO:0031705)
Namespace: molecular_function
Definition: Binding to a bombesin receptor.
Synonyms: bombesin receptor ligand
subtype 3 bombesin receptor binding (GO:0031706)
Namespace: molecular_function
Definition: Binding to a subtype 3 bombesin receptor.
Synonyms: subtype 3 bombesin receptor ligand
endothelin A receptor binding (GO:0031707)
Namespace: molecular_function
Definition: Binding to an endothelin A receptor.
Synonyms: endothelin A receptor ligand; endothelin-1 receptor binding
gastrin-releasing peptide receptor binding (GO:0031709)
Namespace: molecular_function
Definition: Binding to a gastrin-releasing peptide receptor.
Synonyms: gastrin-releasing peptide receptor ligand; GRP receptor binding
neuromedin B receptor binding (GO:0031710)
Namespace: molecular_function
Definition: Binding to a neuromedin B receptor.
Synonyms: neuromedin B receptor ligand
bradykinin receptor binding (GO:0031711)
Namespace: molecular_function
Definition: Binding to a bradykinin receptor.
Synonyms: bradykinin receptor ligand
B2 bradykinin receptor binding (GO:0031713)
Namespace: molecular_function
Definition: Binding to a B2 bradykinin receptor.
Synonyms: B2 bradykinin receptor ligand
C5a anaphylatoxin chemotactic receptor binding (GO:0031714)
Namespace: molecular_function
Definition: Binding to a C5a anaphylatoxin chemotactic receptor.
Synonyms: C5a anaphylatoxin chemotactic receptor ligand
C5L2 anaphylatoxin chemotactic receptor binding (GO:0031715)
Namespace: molecular_function
Definition: Binding to a C5L2 anaphylatoxin chemotactic receptor.
Synonyms: C5L2 anaphylatoxin chemotactic receptor ligand
calcitonin receptor binding (GO:0031716)
Namespace: molecular_function
Definition: Binding to a calcitonin receptor.
Synonyms: calcitonin receptor ligand
cannabinoid receptor binding (GO:0031717)
Namespace: molecular_function
Definition: Binding to a cannabinoid receptor.
Synonyms: cannabinoid receptor ligand
type 1 cannabinoid receptor binding (GO:0031718)
Namespace: molecular_function
Definition: Binding to a type 1 cannabinoid receptor.
Synonyms: type 1 cannabinoid receptor ligand
haptoglobin binding (GO:0031720)
Namespace: molecular_function
Definition: Binding to a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
hemoglobin alpha binding (GO:0031721)
Namespace: molecular_function
Definition: Binding to a hemoglobin alpha chain.
hemoglobin beta binding (GO:0031722)
Namespace: molecular_function
Definition: Binding to a hemoglobin beta chain.
CXCR4 chemokine receptor binding (GO:0031723)
Namespace: molecular_function
Definition: Binding to a CXCR4 chemokine receptor.
Synonyms: CXCR4 chemokine receptor ligand; stromal cell-derived factor 1 receptor binding
CXCR5 chemokine receptor binding (GO:0031724)
Namespace: molecular_function
Definition: Binding to a CXCR5 chemokine receptor.
Synonyms: CXCR5 chemokine receptor ligand; type 1 Burkitt's lymphoma receptor binding
CXCR6 chemokine receptor binding (GO:0031725)
Namespace: molecular_function
Definition: Binding to a CXCR6 chemokine receptor.
Synonyms: bonzo receptor binding; CXCR6 chemokine receptor ligand; STRL33 receptor binding
CCR1 chemokine receptor binding (GO:0031726)
Namespace: molecular_function
Definition: Binding to a CCR1 chemokine receptor.
Synonyms: CCR1 chemokine receptor ligand; macrophage inflammatory protein-1 alpha receptor binding
CCR2 chemokine receptor binding (GO:0031727)
Namespace: molecular_function
Definition: Binding to a CCR2 chemokine receptor.
Synonyms: CCR2 chemokine receptor ligand; monocyte chemoattractant protein 1 receptor binding
CCR3 chemokine receptor binding (GO:0031728)
Namespace: molecular_function
Definition: Binding to a CCR3 chemokine receptor.
Synonyms: CCR3 chemokine receptor ligand; eosinophil eotaxin receptor binding
CCR4 chemokine receptor binding (GO:0031729)
Namespace: molecular_function
Definition: Binding to a CCR4 chemokine receptor.
Synonyms: CCR4 chemokine receptor ligand
CCR5 chemokine receptor binding (GO:0031730)
Namespace: molecular_function
Definition: Binding to a CCR5 chemokine receptor.
Synonyms: CCR5 chemokine receptor ligand
CCR7 chemokine receptor binding (GO:0031732)
Namespace: molecular_function
Definition: Binding to a CCR7 chemokine receptor.
Synonyms: CCR7 chemokine receptor ligand; MIP-3 beta receptor binding; type 1 EBV-induced G-protein coupled receptor binding
CCR8 chemokine receptor binding (GO:0031733)
Namespace: molecular_function
Definition: Binding to a CCR8 chemokine receptor.
Synonyms: CCR8 chemokine receptor ligand
CCR9 chemokine receptor binding (GO:0031734)
Namespace: molecular_function
Definition: Binding to a CCR9 chemokine receptor.
Synonyms: CCR9 chemokine receptor ligand
CCR10 chemokine receptor binding (GO:0031735)
Namespace: molecular_function
Definition: Binding to a CCR10 chemokine receptor.
Synonyms: CCR10 chemokine receptor ligand
CCR11 chemokine receptor binding (GO:0031736)
Namespace: molecular_function
Definition: Binding to a CCR11 chemokine receptor.
Synonyms: CCR11 chemokine receptor ligand
CX3C chemokine receptor binding (GO:0031737)
Namespace: molecular_function
Definition: Binding to a CX3C chemokine receptor.
Synonyms: CX3C chemokine receptor ligand; fractalkine receptor binding
XCR1 chemokine receptor binding (GO:0031738)
Namespace: molecular_function
Definition: Binding to a XCR1 chemokine receptor.
Synonyms: lymphotactin receptor binding; XCR1 chemokine receptor ligand
cholecystokinin receptor binding (GO:0031739)
Namespace: molecular_function
Definition: Binding to a cholecystokinin receptor.
Synonyms: cholecystokinin receptor ligand
type A cholecystokinin receptor binding (GO:0031740)
Namespace: molecular_function
Definition: Binding to a type A cholecystokinin receptor.
Synonyms: type A cholecystokinin receptor ligand
type B gastrin/cholecystokinin receptor binding (GO:0031741)
Namespace: molecular_function
Definition: Binding to a type B gastrin/cholecystokinin receptor.
Synonyms: type B gastrin/cholecystokinin receptor ligand
cysteinyl leukotriene receptor binding (GO:0031745)
Namespace: molecular_function
Definition: Binding to a cysteinyl leukotriene receptor.
Synonyms: cysteinyl leukotriene receptor ligand
type 1 cysteinyl leukotriene receptor binding (GO:0031746)
Namespace: molecular_function
Definition: Binding to a type 1 cysteinyl leukotriene receptor.
Synonyms: type 1 cysteinyl leukotriene receptor ligand
D1 dopamine receptor binding (GO:0031748)
Namespace: molecular_function
Definition: Binding to a D1 dopamine receptor.
Synonyms: D1 dopamine receptor ligand; D1A dopamine receptor binding
D2 dopamine receptor binding (GO:0031749)
Namespace: molecular_function
Definition: Binding to a D2 dopamine receptor.
Synonyms: D2 dopamine receptor ligand
D3 dopamine receptor binding (GO:0031750)
Namespace: molecular_function
Definition: Binding to a D3 dopamine receptor.
Synonyms: D3 dopamine receptor ligand
D4 dopamine receptor binding (GO:0031751)
Namespace: molecular_function
Definition: Binding to a D4 dopamine receptor.
Synonyms: D4 dopamine receptor ligand
D5 dopamine receptor binding (GO:0031752)
Namespace: molecular_function
Definition: Binding to a D5 dopamine receptor.
Synonyms: D1B dopamine receptor binding; D5 dopamine receptor ligand
endothelial differentiation G protein-coupled receptor binding (GO:0031753)
Namespace: molecular_function
Definition: Binding to an endothelial differentiation G protein-coupled receptor.
Synonyms: endothelial differentiation G-protein coupled receptor binding; endothelial differentiation G-protein coupled receptor ligand
Edg-2 lysophosphatidic acid receptor binding (GO:0031755)
Namespace: molecular_function
Definition: Binding to an Edg-2 lysophosphatidic acid receptor.
Synonyms: Edg-2 lysophosphatidic acid receptor ligand; LPA1 receptor binding
Edg-3 sphingosine 1-phosphate receptor binding (GO:0031756)
Namespace: molecular_function
Definition: Binding to an Edg-3 sphingosine 1-phosphate receptor.
Synonyms: Edg-3 sphingosine 1-phosphate receptor ligand