LiteFold/GO huggingface dataset:
negative regulation of smooth muscle cell migration (GO:0014912)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
obsolete regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction (GO:0014915)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of lung blood pressure (GO:0014916)
Namespace: biological_process
Definition: The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.
Synonyms: regulation of pulmonary blood pressure
obsolete positive regulation of diuresis by pressure natriuresis (GO:0014917)
Namespace: biological_process
Definition: OBSOLETE. The process in which pressure natriuresis increases the rate of diuresis.
Synonyms: positive regulation of diuresis by pressure natriuresis
Comment: This term was made obsolete because its definition was inaccurate.
obsolete positive regulation of natriuresis by pressure natriuresis (GO:0014918)
Namespace: biological_process
Definition: OBSOLETE. The process in which pressure natriuresis increases rate of natriuresis.
Synonyms: positive regulation of natriuresis by pressure natriuresis
Comment: This term was made obsolete because its definition was inaccurate.
obsolete polyferredoxin (GO:0015000)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: polyferredoxin
Comment: This term was made obsolete because it does not represent a function.
obsolete high-potential iron-sulfur carrier (GO:0015001)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: high-potential iron-sulfur carrier; high-potential iron-sulphur carrier; HiPIP
Comment: This term was made obsolete because it refers to a class of gene products.
obsolete heme-copper terminal oxidase activity (GO:0015002)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.
Synonyms: haem-copper terminal oxidase activity
Comment: This term was obsoleted because it groups the last enzymes in the electron transport chain, and is not an appropriate grouping term for molecular function.
obsolete copper electron carrier (GO:0015003)
Namespace: molecular_function
Definition: OBSOLETE. A copper-containing entity that serves as an electron acceptor and electron donor in an electron transport system.
Synonyms: copper electron carrier
Comment: This term was made obsolete because it refers to a class of gene products.
obsolete small blue copper electron carrier (GO:0015004)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: small blue copper electron carrier
Comment: This term was made obsolete because it does not represent a molecular function.
obsolete azurin (GO:0015005)
Namespace: molecular_function
Definition: OBSOLETE. Brilliant blue copper-containing protein of low molecular weight found in some bacteria; thought to transfer electrons to cytochrome oxidase. This definition includes pseudoazurin.
Synonyms: azurin
Comment: This term was made obsolete because it does not represent a molecular function.
obsolete plastocyanin (GO:0015006)
Namespace: molecular_function
Definition: OBSOLETE. A copper-containing electron carrier acting between cytochrome b(6)-f and P700 of photosystem I.
Synonyms: plastocyanin
Comment: This term was made obsolete because it does not represent a molecular function.
obsolete electron carrier, chlorophyll electron transport system (GO:0015007)
Namespace: molecular_function
Definition: OBSOLETE. A molecular entity that serves as an electron acceptor and electron donor in a chlorophyll electron transport system.
Synonyms: chlorophyll electron carrier; electron carrier, chlorophyll electron transport system
Comment: This term was made obsolete because it contains both process and function information.
obsolete corrin metabolic process (GO:0015009)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
Synonyms: corrin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete tetrahydrocorphin metabolic process (GO:0015010)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.
Synonyms: tetrahydrocorphin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete nickel-tetrapyrrole coenzyme metabolic process (GO:0015011)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.
Synonyms: coenzyme F430 metabolic process; nickel-tetrapyrrole coenzyme metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
heparan sulfate proteoglycan biosynthetic process (GO:0015012)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of heparan sulfate proteoglycans, which consist of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups, and the latter being e a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparan sulfate chains are covalently linked to serine/threonine residues (O-linked) of the core protein via a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate).
Synonyms: heparan sulfate proteoglycan anabolism; heparan sulfate proteoglycan biosynthesis; heparan sulfate proteoglycan formation; heparan sulfate proteoglycan synthesis; heparan sulphate proteoglycan biosynthesis; heparan sulphate proteoglycan biosynthetic process; heparin proteoglycan biosynthetic process
obsolete heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide (GO:0015013)
Namespace: biological_process
Definition: OBSOLETE. The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.
Synonyms: heparan sulfate proteoglycan anabolism, linkage to polypeptide; heparan sulfate proteoglycan formation, linkage to polypeptide; heparan sulfate proteoglycan synthesis, linkage to polypeptide; heparan sulphate proteoglycan biosynthesis, linkage to polypeptide; heparan sulphate proteoglycan biosynthetic process, linkage to polypeptide; heparin proteoglycan biosynthetic process, linkage to polypeptide
Comment: This term was obsoleted because it represents a molecular function.
obsolete heparan sulfate proteoglycan biosynthetic process, chain elongation (GO:0015014)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.
Synonyms: heparan sulfate proteoglycan anabolism, polysaccharide chain anabolism; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; heparan sulfate proteoglycan chain elongation; heparan sulfate proteoglycan formation, polysaccharide chain biosynthesis; heparan sulfate proteoglycan formation, polysaccharide chain formation; heparan sulfate proteoglycan synthesis, polysaccharide chain synthesis; heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthesis; heparan sulphate proteoglycan biosynthesis, polysaccharide chain biosynthetic process; heparin proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
Comment: This term was obsoleted because it is a subprocess of heparan sulfate proteoglycan biosynthetic process ; GO:0015012.
obsolete heparan sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0015015)
Namespace: biological_process
Definition: OBSOLETE. The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.
Synonyms: heparan sulfate proteoglycan anabolism, enzymatic modification; heparan sulfate proteoglycan formation, enzymatic modification; heparan sulfate proteoglycan synthesis, enzymatic modification; heparan sulphate proteoglycan biosynthesis, enzymatic modification; heparan sulphate proteoglycan biosynthetic process, enzymatic modification; heparin proteoglycan biosynthetic process, enzymatic modification
Comment: This term was obsoleted because it is a subprocess of heparan sulfate proteoglycan biosynthetic process ; GO:0015012.
obsolete glypican (GO:0015017)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: glypican
Comment: This term was made obsolete because it represents a gene product (was misspelled 'glycipan').
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (GO:0015018)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP.
Synonyms: glucuronosyltransferase I activity; UDP-glucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity; UDPglucuronate:3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosyl-protein D-glucuronosyltransferase activity; uridine diphosphate glucuronic acid:acceptor glucuronosyltransferase activity
glucuronosyltransferase activity (GO:0015020)
Namespace: molecular_function
Definition: Catalysis of the reaction: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H+ + UDP.
Synonyms: 1-naphthol glucuronyltransferase activity; 1-naphthol-UDP-glucuronosyltransferase activity; 17-beta-hydroxysteroid UDP-glucuronosyltransferase activity; 17-OH steroid UDPGT activity; 17beta-hydroxysteroid UDP-glucuronosyltransferase activity; 3-alpha-hydroxysteroid UDP-glucuronosyltransferase activity; 3-OH androgenic UDPGT activity; 3alpha-hydroxysteroid UDP-glucuronosyltransferase activity; 4-hydroxybiphenyl UDP-glucuronosyltransferase activity; 4-methylumbelliferone UDP-glucuronosyltransferase activity; 4-nitrophenol UDP-glucuronyltransferase activity; 4-nitrophenol UDPGT activity; bilirubin glucuronyltransferase activity; bilirubin monoglucuronide glucuronyltransferase activity; bilirubin UDP-glucuronosyltransferase activity; bilirubin UDPGT activity; bilirubin uridine diphosphoglucuronyltransferase activity; ciramadol UDP-glucuronyltransferase activity; estriol UDPglucuronosyltransferase activity; estrone UDPglucuronosyltransferase activity; GT activity; morphine glucuronyltransferase activity; p-hydroxybiphenyl UDP glucuronyltransferase activity; p-nitrophenol UDP-glucuronosyltransferase activity; p-nitrophenol UDP-glucuronyltransferase activity; p-nitrophenylglucuronosyltransferase activity; p-phenylphenol glucuronyltransferase activity; phenyl-UDP-glucuronosyltransferase activity; PNP-UDPGT; pnp-UDPGT activity; UDP glucuronate-estradiol-glucuronosyltransferase activity; UDP glucuronate-estriol glucuronosyltransferase activity; UDP glucuronic acid transferase activity; UDP glucuronosyltransferase activity; UDP glucuronyltransferase activity; UDP-glucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); UDP-glucuronate-4-hydroxybiphenyl glucuronosyltransferase activity; UDP-glucuronate-bilirubin glucuronyltransferase activity; UDP-glucuronosyltransferase activity; UDP-glucuronyltransferase activity; UDPGA transferase activity; UDPGA-glucuronyltransferase activity; UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity; UDPGT activity; uridine 5'-diphosphoglucuronyltransferase activity; uridine diphosphate glucuronyltransferase activity; uridine diphosphoglucuronate-1,2-diacylglycerol glucuronosyltransferase activity; uridine diphosphoglucuronate-4-hydroxybiphenyl glucuronosyltransferase activity; uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity; uridine diphosphoglucuronate-bilirubin glucuronosyltransferase activity; uridine diphosphoglucuronate-estradiol glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol 16alpha-glucuronosyltransferase activity; uridine diphosphoglucuronate-estriol glucuronosyltransferase activity; uridine diphosphoglucuronosyltransferase activity; uridine diphosphoglucuronyltransferase activity
heparin-sulfate lyase activity (GO:0015021)
Namespace: molecular_function
Definition: Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.
Synonyms: [heparan sulfate]-sulfate lyase activity; heparin-sulfate eliminase activity; heparin-sulphate lyase activity; heparitin-sulfate lyase activity; heparitinase I; heparitinase II
obsolete syndecan (GO:0015023)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: syndecan
Comment: This term was made obsolete because it represents a gene product.
glucuronate-2-sulfatase activity (GO:0015024)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.
Synonyms: chondro-2-sulfatase activity; glucuronate-2-sulphatase activity; glucurono-2-sulfatase activity; polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase activity
obsolete GPI-anchored membrane-bound receptor (GO:0015025)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: GPI-anchored membrane-bound receptor
Comment: This term was made obsolete because it contains both component and function information.
coreceptor activity (GO:0015026)
Namespace: molecular_function
Definition: Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
Synonyms: coreceptor, insoluble ligand activity; coreceptor, soluble ligand activity
obsolete internalization receptor activity (GO:0015029)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: internalization receptor activity
Comment: This term was made obsolete because internalization is a process, not a ligand to which a receptor might bind.
Cajal body (GO:0015030)
Namespace: cellular_component
Definition: A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
Synonyms: coiled body; Gemini of coiled bodies; Gems
protein transport (GO:0015031)
Namespace: biological_process
Definition: The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: enzyme transport
obsolete storage protein import into fat body (GO:0015032)
Namespace: biological_process
Definition: OBSOLETE. The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.
Synonyms: fat body metabolic process; fat body metabolism; fat body storage protein uptake; import of storage protein into fat body; storage protein import by fat body cells; storage protein import into fat body cells; storage protein transport into fat body cells; storage protein uptake into fat body cells
Comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using 'receptor-mediated endocytosis'.
obsolete cytochrome P450 activity (GO:0015034)
Namespace: molecular_function
Definition: OBSOLETE. A cytochrome b-like protein that has a sulfur atom ligated to the iron of the prosthetic group (heme-thiolate); enzymes: typically monooxygenases acting on, typically, lipophilic substrates. The characteristic mode of action of these enzymes is not electron transfer (some P450 enzymes probably do not even involve the reversible Fe(II)/Fe(III) equilibrium), but rather oxygen atom transfer.
Synonyms: cytochrome P450 activity
Comment: This term was made obsolete because it is a grouping term representing a set of gene products.
protein-disulfide reductase activity (GO:0015035)
Namespace: molecular_function
Definition: Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
Synonyms: haem lyase disulphide oxidoreductase activity; heme lyase disulfide oxidoreductase activity; peptide disulfide oxidoreductase activity; peptide disulphide oxidoreductase activity; protein disulfide oxidoreductase activity; protein disulfide-oxidoreductase activity; protein disulphide oxidoreductase activity
disulfide oxidoreductase activity (GO:0015036)
Namespace: molecular_function
Definition: Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
Synonyms: disulphide oxidoreductase activity
glutathione disulfide oxidoreductase activity (GO:0015038)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
Synonyms: glutaredoxin; glutathione disulphide oxidoreductase activity; glutathione oxidoreductase activity
obsolete electron transfer flavoprotein, group I (GO:0015040)
Namespace: molecular_function
Definition: OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that links acyl-CoA dehydrogenase reactions with the respiratory chain, such as in the fatty acid degradation pathway.
Synonyms: electron transfer flavoprotein, group I
Comment: This term was made obsolete because it refers to a class of gene products.
obsolete electron transfer flavoprotein, group II (GO:0015041)
Namespace: molecular_function
Definition: OBSOLETE. An electron transfer flavoprotein that functions as a housekeeping protein that is synthesized only under certain specific growth conditions and receives electrons from the oxidation of specific substrates, e.g. trimethylamine, carnitine and in nitrogen fixation.
Synonyms: electron transfer flavoprotein, group II
Comment: This term was made obsolete because it refers to a class of gene products.
trypanothione-disulfide reductase (NADPH) activity (GO:0015042)
Namespace: molecular_function
Definition: Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
Synonyms: NADPH:trypanothione oxidoreductase activity; trypanothione reductase activity; trypanothione-disulfide reductase (NADP) activity; trypanothione-disulfide reductase activity; trypanothione-disulphide reductase activity; trypanothione:NADP+ oxidoreductase activity
leghemoglobin reductase [NAD(P)H] activity (GO:0015043)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 Fe(III)-[leghemoglobin] + NAD(P)H = 2 Fe(II)-[leghemoglobin] + NAD(P)+ + H+.
Synonyms: ferric leghemoglobin reductase activity; leghemoglobin reductase activity; NAD(P)H:ferrileghemoglobin oxidoreductase activity
rubredoxin-NAD+ reductase activity (GO:0015044)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 reduced [rubredoxin] + NAD+ + H+ = 2 oxidized [rubredoxin] + NADH.
Synonyms: dihydronicotinamide adenine dinucleotide--rubredoxin reductase activity; DPNH-rubredoxin reductase activity; NADH--rubredoxin oxidoreductase activity; NADH--rubredoxin reductase activity; NADH:rubredoxin oxidoreductase activity; NADH:rubredoxin reductase activity; reduced nicotinamide adenine dinucleotide--rubredoxin reductase activity; rubredoxin--NAD reductase activity; rubredoxin--nicotinamide adenine dinucleotide reductase activity; rubredoxin:NAD+ oxidoreductase activity
rubredoxin-NAD(P)H reductase activity (GO:0015045)
Namespace: molecular_function
Definition: Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.
Synonyms: dinucleotide phosphate reductase activity; NAD(P)--rubredoxin oxidoreductase activity; NAD(P)H--rubredoxin oxidoreductase activity; NADPH:rubredoxin reductase activity; rubredoxin--nicotinamide adenine activity; rubredoxin--nicotinamide adenine dinucleotide (phosphate) reductase activity; rubredoxin:NAD(P)+ oxidoreductase activity
rubredoxin-NADP+ reductase activity (GO:0015046)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 reduced [rubredoxin] + NADP+ + H+ = 2 oxidized [rubredoxin] + NADPH.
NADPH-cytochrome-c2 reductase activity (GO:0015047)
Namespace: molecular_function
Definition: Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.
Synonyms: cytochrome c2 reductase (reduced nicotinamide adinine dinucleotide phosphate, NADPH); NADPH:ferricytochrome-c2 oxidoreductase activity; reductase, cytochrome c2 (reduced nicotinamide adenine dinucleotide phosphate)
obsolete phthalate dioxygenase reductase activity (GO:0015048)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product or it represents a specific substrate.
methane monooxygenase complex (GO:0015050)
Namespace: cellular_component
Definition: A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.
obsolete X-opioid receptor activity (GO:0015051)
Namespace: molecular_function
Definition: OBSOLETE. Combining with an opioid to initiate a change in cell activity, with the pharmacological characteristics of X-opioid receptors.
Synonyms: X-opioid receptor activity
Comment: This term was made obsolete because the receptor is defined based on its pharmacological properties.
beta3-adrenergic receptor activity (GO:0015052)
Namespace: molecular_function
Definition: Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.
Synonyms: beta3 adrenoceptor
gastrin receptor activity (GO:0015054)
Namespace: molecular_function
Definition: Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.
Synonyms: cholecystokinin-B receptor activity
secretin receptor activity (GO:0015055)
Namespace: molecular_function
Definition: Combining with secretin to initiate a change in cell activity.