LiteFold/GO huggingface dataset:
obsolete lytic virus budding from plasma membrane (GO:0046759)
Namespace: biological_process
Definition: OBSOLETE. A form of viral release in which the nucleocapsid evaginates from the host nuclear membrane system, resulting in envelopment of the virus and cell lysis.
Synonyms: lytic plasma membrane viral budding; lytic viral budding from plasma membrane; lytic virus budding from plasma membrane
Comment: This term was made obsolete because it does not appear to correspond to a real biological process.
viral budding from Golgi membrane (GO:0046760)
Namespace: biological_process
Definition: A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.
Synonyms: Golgi membrane viral budding; Golgi membrane viral budding during viral capsid envelopment; viral budding from Golgi membrane by viral capsid envelopment; viral budding from Golgi membrane during viral capsid envelopment; virus budding from Golgi membrane; virus budding from Golgi membrane by viral capsid envelopment; virus budding from Golgi membrane during viral capsid envelopment
viral budding from plasma membrane (GO:0046761)
Namespace: biological_process
Definition: A viral budding that starts with formation of a curvature in the host plasma membrane around which the virion particle assembles.
Synonyms: plasma membrane viral budding; plasma membrane viral budding during viral capsid envelopment; viral budding from plasma membrane by viral capsid envelopment; viral budding from plasma membrane during viral capsid envelopment; virus budding from plasma membrane; virus budding from plasma membrane by viral capsid envelopment; virus budding from plasma membrane during viral capsid envelopment
viral budding from endoplasmic reticulum membrane (GO:0046762)
Namespace: biological_process
Definition: A viral budding that starts with formation of a membrane curvature in the host ER membrane.
Synonyms: endoplasmic reticulum membrane viral budding; endoplasmic reticulum membrane viral budding during viral capsid envelopment; ER membrane viral budding; ER membrane viral budding during viral capsid envelopment; viral budding from ER membrane; viral budding from ER membrane by viral capsid envelopment; viral budding from ER membrane during viral capsid envelopment; virus budding from ER membrane; virus budding from ER membrane by viral capsid envelopment; virus budding from ER membrane during viral capsid envelopment
viral budding from nuclear membrane (GO:0046765)
Namespace: biological_process
Definition: A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.
Synonyms: nuclear membrane viral budding; nuclear membrane viral budding during viral capsid envelopment; viral budding from nuclear membrane by viral capsid envelopment; viral budding from nuclear membrane during viral capsid envelopment; virus budding from nuclear membrane; virus budding from nuclear membrane by viral capsid envelopment; virus budding from nuclear membrane during viral capsid envelopment
viral budding from inner nuclear membrane (GO:0046771)
Namespace: biological_process
Definition: The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.
Synonyms: inner nuclear membrane viral budding during viral capsid envelopment; viral budding from inner nuclear membrane by viral capsid envelopment; viral budding from inner nuclear membrane during viral capsid envelopment; virus budding from inner nuclear membrane by viral capsid envelopment; virus budding from inner nuclear membrane during viral capsid envelopment
viral budding from outer nuclear membrane (GO:0046772)
Namespace: biological_process
Definition: The envelopment of a virus, in which the naked capsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.
Synonyms: outer nuclear membrane viral budding during viral capsid envelopment; viral budding from outer nuclear membrane during viral capsid envelopment; virus budding from outer nuclear membrane by viral capsid envelopment; virus budding from outer nuclear membrane during viral capsid envelopment
symbiont-mediated suppression of host translation termination (GO:0046773)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts translation termination of host mRNAs. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: suppression by virus of host translation termination; viral inhibition of termination of host cell protein biosynthesis; viral inhibition of termination of host cell protein biosynthetic process; viral suppression of termination by host of host cell protein biosynthesis; viral suppression of termination by host of host cell protein biosynthetic process
obsolete suppression by virus of host intracellular interferon activity (GO:0046774)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that results in the inhibition of interferon activity within the host cell.
Synonyms: negative regulation by virus of intracellular interferon activity; suppression by virus of intracellular interferon activity in host
Comment: This term was obsoleted because it was overlapping with symbiont-mediated suppression of host interferon-mediated signaling pathway ; GO:0140886.
obsolete suppression by virus of host cytokine production (GO:0046775)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that results in the inhibition of host cell cytokine production.
Synonyms: negative regulation by virus of host cytokine production
Comment: This term was obsoleted because it was an unnecessary grouping class.
symbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I (GO:0046776)
Namespace: biological_process
Definition: A process by which a symbiont inhibits or disrupts the normal processing and presentation of a peptide antigen on its cell surface in association with an MHC class I transmembrane protein complex. One mechanism of suppression is by direct inhibition of host tapasin, a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, some viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.
Synonyms: inhibition of host MHC class I molecule presentation by virus; negative regulation by virus of MHC class I cell surface presentation; suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I; suppression by virus of host MHC class I cell surface presentation; suppression by virus of host tapasin activity; suppression by virus of MHC class I cell surface presentation in host
obsolete modification by virus of host mRNA processing (GO:0046778)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that interferes with the processing of mRNA in the host cell.
Synonyms: viral perturbation of host mRNA processing
Comment: This term was obsoleted because it is an unnecessary grouing class.
obsolete suppression by virus of expression of host genes with introns (GO:0046779)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed.
Synonyms: negative regulation by virus of expression of host genes with introns; viral inhibition of expression of host genes with introns
Comment: The reason for obsoleting this term is that it is too specific.
symbiont-mediated suppression of host mRNA splicing (GO:0046780)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the splicing of host mRNA, thus interfering with normal host protein production. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: negative regulation by virus of host mRNA splicing; suppression by virus of host mRNA splicing; suppression by virus of host splicing factor activity; viral dispersion of host splicing factors; viral inhibition of host mRNA splicing
regulation of viral transcription (GO:0046782)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the transcription of the viral genome.
obsolete modification by virus of host polysomes (GO:0046783)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that interferes with and inhibits the assembly and function of polysomes.
Synonyms: viral perturbation of polysomes
Comment: This term was obsoleted because it represents the same process as symbiont-mediated inactivation of host ribosome ; GO:0141130.
viral mRNA export from host cell nucleus (GO:0046784)
Namespace: biological_process
Definition: The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.
Synonyms: intronless viral mRNA export from host cell nucleus; intronless viral mRNA export from host nucleus; intronless viral mRNA export out of nucleus; intronless viral mRNA transport from nucleus to cytoplasm; intronless viral mRNA-nucleus export
microtubule polymerization (GO:0046785)
Namespace: biological_process
Definition: The addition of tubulin heterodimers to one or both ends of a microtubule.
Synonyms: microtubule assembly; microtubule formation
viral replication complex formation and maintenance (GO:0046786)
Namespace: biological_process
Definition: The process of organizing and assembling viral replication proteins in preparation for viral replication.
viral DNA repair (GO:0046787)
Namespace: biological_process
Definition: The process of restoring viral DNA after damage or errors in replication.
virion binding (GO:0046790)
Namespace: molecular_function
Definition: Binding to a virion, either by binding to components of the capsid or the viral envelope.
obsolete suppression by virus of host complement neutralization (GO:0046791)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that results in the inhibition of complement neutralization of the host cell.
Synonyms: negative regulation by virus of host complement neutralization; suppression by virus of host complement neutralization
Comment: This term was made obsolete because the meaning of the term is unclear. It most likely refers to inhibiting the process by which a virus particle is neutralized by the host cell in a complement-dependent manner.
obsolete suppression by virus of host cell cycle arrest (GO:0046792)
Namespace: biological_process
Definition: OBSOLETE. Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur.
Synonyms: negative regulation by virus of cell cycle arrest; viral inhibition of cell cycle arrest
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete induction by virus of phosphorylation of host RNA polymerase II (GO:0046793)
Namespace: biological_process
Definition: OBSOLETE. Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II.
Synonyms: induction by virus of modification of host RNA polymerase II; virus-induced modification of host RNA polymerase II
Comment: This term was obsoleted because it is a molecular function represented as a biological process.
transport of virus (GO:0046794)
Namespace: biological_process
Definition: The directed movement of a virus, or part of a virus, into, out of, or within a host cell.
Synonyms: viral transport; virion transport
viral procapsid maturation (GO:0046797)
Namespace: biological_process
Definition: The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.
Synonyms: capsid maturation; viral capsid maturation; virion maturation
viral portal complex (GO:0046798)
Namespace: cellular_component
Definition: A multimeric ring of proteins through which the DNA enters and exits the viral capsid.
obsolete recruitment of helicase-primase complex to DNA lesions (GO:0046799)
Namespace: biological_process
Definition: OBSOLETE. The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete enhancement of virulence (GO:0046800)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the severity of viral infection and subsequent disease.
Synonyms: enhancement of virulence
Comment: This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.
obsolete reduction of virulence (GO:0046803)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the severity of viral infection and subsequent disease.
Synonyms: reduction of virulence
Comment: This term was made obsolete because 'virulence' is not a biological process; however, alteration of virulence also does not fit under 'regulation of biological quality ; GO:0065008' because it is a product both of the genotype/phenotype of the infecting organism and the genotype/phenotype of the organism being infected and varies by individual within a species both for the infecting organism and the infected organism.
obsolete peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (GO:0046804)
Namespace: biological_process
Definition: OBSOLETE. The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine.
Synonyms: peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulphoxide
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined.
obsolete protein-heme linkage via 1'-L-histidine (GO:0046805)
Namespace: biological_process
Definition: OBSOLETE. The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).
Synonyms: protein-haem linkage via 1'-L-histidine
Comment: This term was obsoleted because it represents a molecular function.
viral scaffold (GO:0046806)
Namespace: cellular_component
Definition: A complex of proteins that form a scaffold around which the viral capsid is constructed.
viral scaffold assembly and maintenance (GO:0046807)
Namespace: biological_process
Definition: The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.
Comment: See also the cellular component term 'viral scaffold ; GO:0046806'.
obsolete assemblon (GO:0046808)
Namespace: cellular_component
Definition: OBSOLETE. Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously.
Comment: This term was obsoleted because it does not correspond to a real cellular component, but to a site of immunoreactivity.
replication compartment (GO:0046809)
Namespace: cellular_component
Definition: Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.
Synonyms: RC
host cell extracellular matrix binding (GO:0046810)
Namespace: molecular_function
Definition: Binding to the extracellular matrix of a host cell.
histone deacetylase inhibitor activity (GO:0046811)
Namespace: molecular_function
Definition: Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.
host cell surface binding (GO:0046812)
Namespace: molecular_function
Definition: Binding to the surface of a host cell.
receptor-mediated virion attachment to host cell (GO:0046813)
Namespace: biological_process
Definition: The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.
Synonyms: virion attachment, binding of host cell surface receptor
coreceptor-mediated virion attachment to host cell (GO:0046814)
Namespace: biological_process
Definition: The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.
Synonyms: virion attachment, binding of host cell surface coreceptor
obsolete genome retention in viral capsid (GO:0046815)
Namespace: biological_process
Definition: OBSOLETE. Any process in which the viral genome is retained within the capsid during genome cleavage and packaging.
Comment: This term was obsoleted because it represents an assay.
chemokine receptor antagonist activity (GO:0046817)
Namespace: molecular_function
Definition: Interacts with chemokine receptors to reduce the action of a chemokine.
dense nuclear body (GO:0046818)
Namespace: cellular_component
Definition: A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.
protein secretion by the type V secretion system (GO:0046819)
Namespace: biological_process
Definition: The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.
Synonyms: autotransporter system; protein secretion by the autotransporter system; protein secretion by the type V protein secretion system; type V protein secretion system
aminodeoxychorismate synthase activity (GO:0046820)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.
Synonyms: 4-amino-4-deoxychorismate synthase activity; ADC synthase activity; chorismate:L-glutamine amido-ligase activity; p-aminobenzoate synthetase; PabB activity; para-aminobenzoic acid (PABA) synthase; para-aminobenzoic acid synthase activity
Comment: Note that the name 'para-aminobenzoic acid synthase' was initially given to the 'aminodeoxychorismate synthase' activity before the additional 4-amino-4-deoxychorismate lyase activity was discovered. It is the lyase activity that actually produces para-aminobenzoic acid from 4-amino-4-deoxychorismate.
extrachromosomal DNA (GO:0046821)
Namespace: cellular_component
Definition: DNA structures that are not part of a chromosome.
regulation of nucleocytoplasmic transport (GO:0046822)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
negative regulation of nucleocytoplasmic transport (GO:0046823)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
Synonyms: down regulation of nucleocytoplasmic transport; down-regulation of nucleocytoplasmic transport; downregulation of nucleocytoplasmic transport; inhibition of nucleocytoplasmic transport
positive regulation of nucleocytoplasmic transport (GO:0046824)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
Synonyms: activation of nucleocytoplasmic transport; stimulation of nucleocytoplasmic transport; up regulation of nucleocytoplasmic transport; up-regulation of nucleocytoplasmic transport; upregulation of nucleocytoplasmic transport
regulation of protein export from nucleus (GO:0046825)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.
Synonyms: regulation of protein export from cell nucleus; regulation of protein export out of nucleus; regulation of protein transport from nucleus to cytoplasm; regulation of protein-nucleus export
negative regulation of protein export from nucleus (GO:0046826)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.
Synonyms: down regulation of protein export from nucleus; down-regulation of protein export from nucleus; downregulation of protein export from nucleus; inhibition of protein export from nucleus; negative regulation of protein export from cell nucleus; negative regulation of protein export out of nucleus; negative regulation of protein transport from nucleus to cytoplasm; negative regulation of protein-nucleus export
positive regulation of protein export from nucleus (GO:0046827)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
Synonyms: activation of protein export from nucleus; positive regulation of protein export from cell nucleus; positive regulation of protein export out of nucleus; positive regulation of protein transport from nucleus to cytoplasm; positive regulation of protein-nucleus export; stimulation of protein export from nucleus; up regulation of protein export from nucleus; up-regulation of protein export from nucleus; upregulation of protein export from nucleus
regulation of RNA import into nucleus (GO:0046828)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.
Synonyms: regulation of RNA import into cell nucleus; regulation of RNA transport from cytoplasm to nucleus; regulation of RNA-nucleus import
negative regulation of RNA import into nucleus (GO:0046829)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.
Synonyms: down regulation of RNA import into nucleus; down-regulation of RNA import into nucleus; downregulation of RNA import into nucleus; inhibition of RNA import into nucleus; negative regulation of RNA import into cell nucleus; negative regulation of RNA transport from cytoplasm to nucleus; negative regulation of RNA-nucleus import
positive regulation of RNA import into nucleus (GO:0046830)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.
Synonyms: activation of RNA import into nucleus; positive regulation of RNA import into cell nucleus; positive regulation of RNA transport from cytoplasm to nucleus; positive regulation of RNA-nucleus import; stimulation of RNA import into nucleus; up regulation of RNA import into nucleus; up-regulation of RNA import into nucleus; upregulation of RNA import into nucleus