LiteFold/GO huggingface dataset:
polyphosphate-mediated signaling (GO:0110094)
Namespace: biological_process
Definition: Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.
Synonyms: polyphosphate signaling
cellular detoxification of aldehyde (GO:0110095)
Namespace: biological_process
Definition: Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
cellular response to aldehyde (GO:0110096)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus.
regulation of calcium import into the mitochondrion (GO:0110097)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of calcium import into the mitochondrion.
positive regulation of calcium import into the mitochondrion (GO:0110098)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of calcium import into the mitochondrion.
negative regulation of calcium import into the mitochondrion (GO:0110099)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into the mitochondrion.
spindle pole body separation (GO:0110100)
Namespace: biological_process
Definition: The release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that is severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar spindle to assemble.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
L-valine transmembrane import into vacuole (GO:0110101)
Namespace: biological_process
Definition: The directed movement of L-valine into the vacuole across the vacuolar membrane.
ribulose bisphosphate carboxylase complex assembly (GO:0110102)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a ribulose bisphosphate carboxylase complex.
Synonyms: RuBisCO assembly
RNA polymerase II termination complex (GO:0110103)
Namespace: cellular_component
Definition: A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end.
Synonyms: TXT complex
Comment: In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.
mRNA alternative polyadenylation (GO:0110104)
Namespace: biological_process
Definition: The process of generating multiple mRNA molecules with variable 3'-end length formation from a given pre-mRNA by differential use of cleavage and polyadenylation signals (pA signals).
mRNA cleavage and polyadenylation specificity factor complex assembly (GO:0110105)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the mRNA cleavage and polyadenylation specificity factor complex.
regulation of imaginal disc-derived wing vein specification (GO:0110107)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of imaginal disc-derived wing vein specification.
negative regulation of imaginal disc-derived wing vein specification (GO:0110109)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived wing vein specification.
positive regulation of animal organ morphogenesis (GO:0110110)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.
negative regulation of animal organ morphogenesis (GO:0110111)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis.
obsolete negative regulation of lipid transporter activity (GO:0110114)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate, or extent of lipid transporter activity.
Comment: This term was obsoleted because it represents a molecular function.
Cdr2 medial cortical node complex (GO:0110115)
Namespace: cellular_component
Definition: A megadalton-sized complex at the medial cortex organized as an oligomeric core of SAD family protein kinases involved in cell size-dependent localization and phosphorylation of Wee1 during interphase.
Synonyms: interphase cortical node; interphase node
positive regulation of compound eye photoreceptor cell differentiation (GO:0110117)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation.
negative regulation of compound eye photoreceptor cell differentiation (GO:0110118)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation.
positive regulation of very-low-density lipoprotein particle clearance (GO:0110119)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of very-low-density lipoprotein particle clearance.
gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body (GO:0110121)
Namespace: biological_process
Definition: Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.
myotube cell migration (GO:0110122)
Namespace: biological_process
Definition: The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse.
regulation of myotube cell migration (GO:0110123)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of myotube cell migration.
positive regulation of myotube cell migration (GO:0110124)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration.
negative regulation of myotube cell migration (GO:0110125)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration.
phloem loading (GO:0110126)
Namespace: biological_process
Definition: The process of loading solutes into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
phloem unloading (GO:0110127)
Namespace: biological_process
Definition: The process of unloading solutes that are produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
phloem sucrose unloading (GO:0110128)
Namespace: biological_process
Definition: The process of unloading sucrose that is produced in the source tissues, from the sieve tube or companion cell of the phloem into the sink tissues.
obsolete SHREC2 complex (GO:0110129)
Namespace: cellular_component
Definition: OBSOLETE. A histone deacetylase complex formed by the association of an HP1 protein with a SHREC complex. The SHREC2 complex is required for deacetylation of H3K14, and mediates transcriptional gene silencing by limiting RNA polymerase II access to heterochromatin. In fission yeast, the complex contains the SHREC subunits Clr1, Clr2, Clr3, and Mit1, and the HP1 protein Chp2.
Comment: This term was added in error.
ribitol-5-phosphatase activity (GO:0110130)
Namespace: molecular_function
Definition: Catalysis of the reaction: ribitol-5-phosphate + H20 = ribitol + phosphate.
Aim21-Tda2 complex (GO:0110131)
Namespace: cellular_component
Definition: A complex that localizes to actin cortical patches at sites of endocytosis and negatively regulates barbed end F-actin assembly, resulting in the generation of free actin pools. The Aim21-Tda2 complex is necessary for efficient endocytosis and balancing the distribution of actin between patches and cables.
Synonyms: Aim21/Tda2 complex
obsolete regulation of CRISPR-cas system (GO:0110132)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a CRISPR-cas system.
Comment: This term was obsoleted because it does not accurately capture the process described in the literature.
obsolete negative regulation of CRISPR-cas system (GO:0110133)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a CRISPR-cas system.
Comment: This term was obsoleted because it does not accurately capture the process described in the literature.
meiotic drive (GO:0110134)
Namespace: biological_process
Definition: A biological process that results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to gametes. In the absence of meiotic drive, the two copies of each gene or chromosome in a diploid organism are transmitted to offspring with equal probability, whereas meiotic drive results in overrepresentation of the driving allele among the surviving products of meiosis.
protein-RNA complex remodeling (GO:0110136)
Namespace: biological_process
Definition: The acquisition, loss, or modification of macromolecules within a protein-RNA complex, resulting in the alteration of an existing complex.
Synonyms: protein-RNA complex remodelling
positive regulation of imaginal disc-derived leg joint morphogenesis (GO:0110138)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
negative regulation of imaginal disc-derived leg joint morphogenesis (GO:0110139)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis.
flagellum attachment zone organization (GO:0110140)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a flagellum attachment zone. FAZ is a network of cytoskeletal and membranous connections responsible for the lateral attachment of the cilium to the cell body in some trypanosomatid species.
Synonyms: FAZ organization; flagellum attachment zone organisation
L-glutamate import into mitochondrion (GO:0110141)
Namespace: biological_process
Definition: The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix.
ubiquinone biosynthesis complex (GO:0110142)
Namespace: cellular_component
Definition: A protein complex composed of enzymes and accessory factors of the ubiquinone (CoQ) biosynthesis pathway. In E. coli, the complex is composed of seven proteins: UbiE, F, G, H, I, J and K. In eukaryotes, the complex is located on the matrix face of the inner mitochondrial membrane and includes COQ3, COQ4, COQ5, COQ6, COQ7, COQ9.
Synonyms: complex Q; CoQ Biosynthetic Complex; CoQ metabolon; CoQ-synthome; Ubi complex
magnetosome (GO:0110143)
Namespace: cellular_component
Definition: A membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria. Magnetosomes form linear chains that align along the cellular motility axis at midcell and function in bacterial navigation along the Earth's magnetic field. They are formed by invagination of the cell inner membrane; in some species they remain connected to the inner membrane, in others they pinch off to form independent intracellular vesicles.
obsolete magnetosome part (GO:0110144)
Namespace: cellular_component
Definition: OBSOLETE. Any constituent part of a magnetosome, a membrane-bound organelle that envelops particles of magnetic iron minerals in magnetotactic bacteria.
magnetosome lumen (GO:0110145)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of a magnetosome.
magnetosome membrane (GO:0110146)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a magnetosome.
obsolete protein maturation by nickel ion transfer (GO:0110147)
Namespace: biological_process
Definition: OBSOLETE. A process that contributes to the delivery of nickel ions to a target protein to facilitate its maturation.
Comment: The reason for obsoletion is that these BP terms represent MFs.
obsolete regulation of biomineralization (GO:0110149)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
Synonyms: regulation of biomineral formation; regulation of biomineralisation; regulation of mineralisation; regulation of mineralization
Comment: This term was obsoleted because it grouped multicellular organism processes and cellular processes.
obsolete negative regulation of biomineralization (GO:0110150)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
Synonyms: negative regulation of biomineral formation; negative regulation of biomineralisation; negative regulation of mineralisation; negative regulation of mineralization
Comment: This term was obsoleted because it grouped multicellular organism processes and cellular processes.
obsolete positive regulation of biomineralization (GO:0110151)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms.
Synonyms: positive regulation of biomineral formation; positive regulation of biomineralisation; positive regulation of mineralisation; positive regulation of mineralization
Comment: This term was obsoleted because it grouped multicellular organism processes and cellular processes.
RNA NAD+-cap (NAD+-forming) hydrolase activity (GO:0110152)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.
Synonyms: RNA NAD-cap (NAD-forming) hydrolase activity
Comment: This reaction specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
RNA NAD-cap (NMN-forming) hydrolase activity (GO:0110153)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+.
Comment: This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.
RNA decapping (GO:0110154)
Namespace: biological_process
Definition: Cleavage of the 5'-cap of an RNA.
NAD-cap decapping (GO:0110155)
Namespace: biological_process
Definition: Cleavage of the 5'-NAD-cap of an RNA. The NAD-cap is present at the 5'-end of some RNAs in both bacetria and eukaryotes. While it promotes RNA stability in bacteria, it promotes RNA decay in eukaryotes.
mRNA methylguanosine-cap decapping (GO:0110156)
Namespace: biological_process
Definition: Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.
reelin complex (GO:0110157)
Namespace: cellular_component
Definition: An extracellular complex that binds lipoprotein receptors VLDLR and APOER2, cadherin-related neuronal receptors (CNRs) or alpha3beta1 integrin and induces various downstream, reelin-dependent, phosphorylation cascades. It ultimately affects polarization, differentiation, neuronal migration and layer formation in the embryonic brain and neuron growth, maturation, and synaptic activity in the postnatal and adult brain.
calpain complex (GO:0110158)
Namespace: cellular_component
Definition: A calcium-dependent protease complex that processes its substrate by limited proteolysis rather than degrading it. In some cases limited proteolysis is required for the activation of its substrate.
Synonyms: M-calpain; mu-calpain
regulation of mitotic spindle formation (spindle phase one) (GO:0110159)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
negative regulation of mitotic spindle formation (spindle phase one) (GO:0110160)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
regulation of mitotic spindle elongation (spindle phase three) (GO:0110162)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
negative regulation of mitotic spindle elongation (spindle phase three) (GO:0110163)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
positive regulation of mitotic spindle elongation (spindle phase three) (GO:0110164)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B (spindle phase three).
cellular anatomical structure (GO:0110165)
Namespace: cellular_component
Definition: A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses.
Synonyms: cellular anatomical entity
DNA synthesis involved in mitochondrial DNA replication (GO:0110166)
Namespace: biological_process
Definition: Any DNA biosynthetic process that is involved in mitochondrial DNA replication.
Synonyms: DNA biosynthetic process involved in mitochondrial DNA replication
fusiform vesicle (GO:0120002)
Namespace: cellular_component
Definition: A cytoplasmic vesicle which contains two urothelial plaques and can deliver these plaques to the apical plasma membrane of urothelial superficial (umbrella) cells. It can also be formed by endocytosis of apical plasma membrane during contractions of the urinary bladder.
hinge region between urothelial plaques of apical plasma membrane (GO:0120003)
Namespace: cellular_component
Definition: A narrow rim of non-thickened membrane in between urothelial plaques in apical plasma membrane.
regulation of glutamatergic neuron differentiation (GO:0120006)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation.
negative regulation of glutamatergic neuron differentiation (GO:0120007)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation.
positive regulation of glutamatergic neuron differentiation (GO:0120008)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation.
intermembrane lipid transfer (GO:0120009)
Namespace: biological_process
Definition: The transport of lipids between membranes in which a lipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
intermembrane phospholipid transfer (GO:0120010)
Namespace: biological_process
Definition: The transport of phospholipids between membranes in which a phospholipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane.
intermembrane sterol transfer (GO:0120011)
Namespace: biological_process
Definition: The transport of sterols between membranes in which a sterol molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
intermembrane sphingolipid transfer (GO:0120012)
Namespace: biological_process
Definition: The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).
lipid transfer activity (GO:0120013)
Namespace: molecular_function
Definition: Removes a lipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. This results in intermembrane transfer of lipids.
Synonyms: intermembrane lipid transfer activity; lipid carrier activity
phospholipid transfer activity (GO:0120014)
Namespace: molecular_function
Definition: Removes a phospholipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: intermembrane phospholipid transfer activity; phospholipid carrier activity
sterol transfer activity (GO:0120015)
Namespace: molecular_function
Definition: Removes a sterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: intermembrane sterol transfer activity; sterol carrier activity
sphingolipid transfer activity (GO:0120016)
Namespace: molecular_function
Definition: Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: intermembrane sphingolipid transfer activity; sphingolipid carrier activity
ceramide transfer activity (GO:0120017)
Namespace: molecular_function
Definition: Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: ceramide carrier activity; ceramide transporter activity; intermembrane ceramide transfer activity