LiteFold/GO huggingface dataset:
regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051946)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
Synonyms: regulation of glutamate reuptake; regulation of glutamate uptake during transmission of nerve impulse; regulation of glutamate uptake involved in conduction of nerve impulse; regulation of L-glutamate reuptake; regulation of L-glutamate uptake during transmission of nerve impulse
obsolete regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse (GO:0051947)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
Synonyms: regulation of 4-aminobutyrate reuptake; regulation of 4-aminobutyrate uptake during transmission of nerve impulse; regulation of GABA reuptake; regulation of GABA uptake during transmission of nerve impulse; regulation of gamma-aminobutyric acid reuptake; regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete negative regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051948)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
Synonyms: down regulation of glutamate uptake during transmission of nerve impulse; down-regulation of glutamate uptake during transmission of nerve impulse; downregulation of glutamate uptake during transmission of nerve impulse; inhibition of glutamate uptake during transmission of nerve impulse; negative regulation of glutamate reuptake; negative regulation of glutamate uptake during transmission of nerve impulse; negative regulation of glutamate uptake involved in conduction of nerve impulse
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse (GO:0051949)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
Synonyms: down regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; down-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; downregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; inhibition of gamma-aminobutyric acid uptake during transmission of nerve impulse; negative regulation of 4-aminobutyrate reuptake; negative regulation of 4-aminobutyrate uptake during transmission of nerve impulse; negative regulation of GABA reuptake; negative regulation of GABA uptake during transmission of nerve impulse; negative regulation of gamma-aminobutyric acid reuptake; negative regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; negative regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse (GO:0051950)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
Synonyms: activation of gamma-aminobutyric acid uptake during transmission of nerve impulse; positive regulation of 4-aminobutyrate reuptake; positive regulation of 4-aminobutyrate uptake during transmission of nerve impulse; positive regulation of GABA reuptake; positive regulation of GABA uptake during transmission of nerve impulse; positive regulation of gamma-aminobutyric acid reuptake; positive regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; positive regulation of gamma-aminobutyric acid uptake involved in conduction of nerve impulse; stimulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; up regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; up-regulation of gamma-aminobutyric acid uptake during transmission of nerve impulse; upregulation of gamma-aminobutyric acid uptake during transmission of nerve impulse
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
positive regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051951)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
Synonyms: activation of glutamate uptake during transmission of nerve impulse; positive regulation of glutamate reuptake; positive regulation of glutamate uptake during transmission of nerve impulse; positive regulation of glutamate uptake involved in conduction of nerve impulse; stimulation of glutamate uptake during transmission of nerve impulse; up regulation of glutamate uptake during transmission of nerve impulse; up-regulation of glutamate uptake during transmission of nerve impulse; upregulation of glutamate uptake during transmission of nerve impulse
regulation of amine transport (GO:0051952)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of amine transport (GO:0051953)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: down regulation of amine transport; down-regulation of amine transport; downregulation of amine transport; inhibition of amine transport
positive regulation of amine transport (GO:0051954)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: activation of amine transport; stimulation of amine transport; up regulation of amine transport; up-regulation of amine transport; upregulation of amine transport
regulation of amino acid transport (GO:0051955)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of amino acid transport (GO:0051956)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: down regulation of amino acid transport; down-regulation of amino acid transport; downregulation of amino acid transport; inhibition of amino acid transport; negative regulation of amino acid transmembrane transport
positive regulation of amino acid transport (GO:0051957)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: activation of amino acid transport; positive regulation of amino acid transmembrane transport; stimulation of amino acid transport; up regulation of amino acid transport; up-regulation of amino acid transport; upregulation of amino acid transport
methotrexate transport (GO:0051958)
Namespace: biological_process
Definition: The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
dynein light intermediate chain binding (GO:0051959)
Namespace: molecular_function
Definition: Binding to a light intermediate chain of the dynein complex.
regulation of nervous system development (GO:0051960)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
negative regulation of nervous system development (GO:0051961)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
Synonyms: down regulation of nervous system development; down-regulation of nervous system development; downregulation of nervous system development; inhibition of nervous system development
positive regulation of nervous system development (GO:0051962)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
Synonyms: activation of nervous system development; stimulation of nervous system development; up regulation of nervous system development; up-regulation of nervous system development; upregulation of nervous system development
regulation of synapse assembly (GO:0051963)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
Synonyms: regulation of synapse biogenesis; regulation of synaptogenesis
negative regulation of synapse assembly (GO:0051964)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
Synonyms: down regulation of synapse assembly; down-regulation of synapse assembly; downregulation of synapse assembly; inhibition of synapse assembly; negative regulation of synapse biogenesis; negative regulation of synaptogenesis
positive regulation of synapse assembly (GO:0051965)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
Synonyms: activation of synapse assembly; positive regulation of synapse biogenesis; positive regulation of synaptogenesis; stimulation of synapse assembly; up regulation of synapse assembly; up-regulation of synapse assembly; upregulation of synapse assembly
regulation of synaptic transmission, glutamatergic (GO:0051966)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
negative regulation of synaptic transmission, glutamatergic (GO:0051967)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
Synonyms: down regulation of synaptic transmission, glutamatergic; down-regulation of synaptic transmission, glutamatergic; downregulation of synaptic transmission, glutamatergic; inhibition of synaptic transmission, glutamatergic
positive regulation of synaptic transmission, glutamatergic (GO:0051968)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
Synonyms: activation of synaptic transmission, glutamatergic; stimulation of synaptic transmission, glutamatergic; up regulation of synaptic transmission, glutamatergic; up-regulation of synaptic transmission, glutamatergic; upregulation of synaptic transmission, glutamatergic
regulation of transmission of nerve impulse (GO:0051969)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
Synonyms: regulation of conduction of nerve impulse
negative regulation of transmission of nerve impulse (GO:0051970)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
Synonyms: down regulation of transmission of nerve impulse; down-regulation of transmission of nerve impulse; downregulation of transmission of nerve impulse; inhibition of transmission of nerve impulse; negative regulation of conduction of nerve impulse
obsolete regulation of telomerase activity (GO:0051972)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
Synonyms: telomerase regulator
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete negative regulation of telomerase activity (GO:0051974)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Synonyms: down regulation of telomerase activity; down-regulation of telomerase activity; downregulation of telomerase activity; inhibition of telomerase activity; telomerase inhibitor
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete L-lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:0051975)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of L-lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.
Synonyms: lysine biosynthesis via aminoadipic acid and saccharopine; lysine biosynthetic process via aminoadipic acid and saccharopine
Comment: The reason for obsoletion is that this term represents a GO-CAM model.
obsolete L-lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate (GO:0051976)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of L-lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.
Synonyms: lysine biosynthesis via aminoadipic acid and N2-acetyl-alpha-aminoadipate; lysine biosynthetic process via aminoadipic acid and N2-acetyl-alpha-aminoadipate
Comment: The reason for obsoletion is that this term represents a GO-CAM model.
lysophospholipid:sodium symporter activity (GO:0051978)
Namespace: molecular_function
Definition: Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
Synonyms: lysophospholipid transporter activity
alginic acid acetylation (GO:0051979)
Namespace: biological_process
Definition: The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.
Synonyms: alginate acetylation
copper chelate transmembrane transporter activity (GO:0051981)
Namespace: molecular_function
Definition: Enables the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
regulation of chromosome segregation (GO:0051983)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
positive regulation of chromosome segregation (GO:0051984)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
Synonyms: activation of chromosome segregation; stimulation of chromosome segregation; up regulation of chromosome segregation; up-regulation of chromosome segregation; upregulation of chromosome segregation
negative regulation of chromosome segregation (GO:0051985)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
Synonyms: down regulation of chromosome segregation; down-regulation of chromosome segregation; downregulation of chromosome segregation; inhibition of chromosome segregation
negative regulation of attachment of spindle microtubules to kinetochore (GO:0051986)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
Synonyms: down regulation of attachment of spindle microtubules to kinetochore; down-regulation of attachment of spindle microtubules to kinetochore; downregulation of attachment of spindle microtubules to kinetochore; inhibition of attachment of spindle microtubules to kinetochore
coproporphyrinogen dehydrogenase activity (GO:0051989)
Namespace: molecular_function
Definition: Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
Synonyms: coproporphyrinogen III oxidase activity; coproporphyrinogen-III:S-adenosyl-L-methionine oxidoreductase (decarboxylating); HemN; oxygen-independent coproporphyrinogen-III oxidase activity; radical SAM enzyme activity
(R)-2-hydroxyglutarate dehydrogenase activity (GO:0051990)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
Synonyms: D-2-hydroxyglutarate dehydrogenase activity
UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity (GO:0051992)
Namespace: molecular_function
Definition: Catalysis of the reaction: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP.
Comment: Note that EC classifies 'UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity ; GO:0051992' and 'phospho-N-acetylmuramoyl-pentapeptide-transferase activity ; GO:0008963' under the same EC number, EC:2.7.8.13.
abscisic acid glucose ester beta-glucosidase activity (GO:0051993)
Namespace: molecular_function
Definition: Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.
Synonyms: ABA-GE beta-glucosidase activity
obsolete P-methyltransferase activity (GO:0051994)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.
Comment: This term was obsoleted because it represents a specific substrate.
Se-methyltransferase activity (GO:0051995)
Namespace: molecular_function
Definition: Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.
squalene synthase [NAD(P)H] activity (GO:0051996)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 (2E,6E)-farnesyl diphosphate + H+ + NAD(P)H = 2 diphosphate + NAD(P)+ + squalene.
Synonyms: farnesyl-diphosphate farnesyltransferase activity; farnesyltransferase activity; presqualene synthase activity; presqualene-diphosphate synthase activity; squalene synthase activity; squalene synthetase activity
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity (GO:0051997)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.
Synonyms: 4-(carbamoylamino)-5-hydroxy-2-oxo-2,5-dihydro-1H-imidazole-5-carboxylate decarboxylase activity; OHCU decarboxylase activity
protein carboxyl O-methyltransferase activity (GO:0051998)
Namespace: molecular_function
Definition: Catalysis of the transfer of a methyl group to a carboxyl group on a protein.
Synonyms: protein carboxyl methyltransferase activity
mannosyl-inositol phosphorylceramide biosynthetic process (GO:0051999)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
Synonyms: mannose inositol phosphoceramide biosynthetic process; mannose-inositol-P-ceramide (MIPC) biosynthetic process; mannosyl-inositol phosphorylceramide anabolism; mannosyl-inositol phosphorylceramide biosynthesis; mannosyl-inositol phosphorylceramide formation; mannosyl-inositol phosphorylceramide synthesis; MIPC biosynthetic process