LiteFold/GO huggingface dataset:
effector-mediated activation of host programmed cell death by symbiont (GO:0034055)
Namespace: biological_process
Definition: A symbiont process in which a molecule secreted by the symbiont activates a programmed cell death pathway in the host to suppress the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: activation by symbiont of host defense-related programmed cell death; effector-mediated activation of programmed cell death in host; effector-mediated induction of programmed cell death in host; enhancement by symbiont of host defense-related programmed cell death; positive regulation by symbiont of host defense-related PCD; positive regulation by symbiont of host defense-related programmed cell death; stimulation by symbiont of host defense-related programmed cell death; up regulation by symbiont of host defense-related programmed cell death; up-regulation by symbiont of host defense-related programmed cell death; upregulation by symbiont of host defense-related programmed cell death
Comment: Note that this term is used to annotate gene products of the symbiont.
estrogen response element binding (GO:0034056)
Namespace: molecular_function
Definition: Binding to an estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
Synonyms: ERE binding
RNA strand-exchange activity (GO:0034057)
Namespace: molecular_function
Definition: Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.
endosomal vesicle fusion (GO:0034058)
Namespace: biological_process
Definition: The homotypic fusion of endocytic vesicles to form or add to an early endosome.
Synonyms: endosome vesicle fusion
response to anoxia (GO:0034059)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
Synonyms: response to anoxic stress
Comment: Note that this term should not be confused with 'response to hypoxia ; GO:0001666'.
cyanelle stroma (GO:0034060)
Namespace: cellular_component
Definition: The space enclosed by the double membrane of a cyanelle.
DNA polymerase activity (GO:0034061)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).
5'-3' RNA polymerase activity (GO:0034062)
Namespace: molecular_function
Definition: Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.
Synonyms: RNA polymerase activity
stress granule assembly (GO:0034063)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
Synonyms: SG assembly
Tor2-Mei2-Ste11 complex (GO:0034064)
Namespace: cellular_component
Definition: A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.
Ric1-Rgp1 guanyl-nucleotide exchange factor complex (GO:0034066)
Namespace: cellular_component
Definition: A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.
Synonyms: Ric1p-Rgp1p complex
protein localization to Golgi apparatus (GO:0034067)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
Synonyms: establishment of protein localisation to Golgi; establishment of protein localization in Golgi; establishment of protein localization to Golgi; establishment of protein localization to Golgi apparatus; protein localisation in Golgi apparatus; protein localization in Golgi apparatus; protein targeting to Golgi; protein-Golgi targeting
aminoglycoside N-acetyltransferase activity (GO:0034069)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.
Synonyms: kanamycin acetyltransferase activity
obsolete aminoglycoside 1-N-acetyltransferase activity (GO:0034070)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product or it represents a specific substrate.
aminoglycoside phosphotransferase activity (GO:0034071)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.
Synonyms: aminoglycoside kinase activity
squalene cyclase activity (GO:0034072)
Namespace: molecular_function
Definition: Catalysis of the reaction: squalene = triterpene.
tetrahymanol synthase activity (GO:0034073)
Namespace: molecular_function
Definition: Catalysis of the reaction: tetrahymanol = squalene + H2O.
Synonyms: squalene--tetrahymanol cyclase activity; tetrahymanol cyclase activity
Comment: The reaction occurs in the reverse direction.
marneral synthase activity (GO:0034074)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-2,3-epoxysqualene = marneral.
arabidiol synthase activity (GO:0034075)
Namespace: molecular_function
Definition: Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).
cucurbitadienol synthase activity (GO:0034076)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-2,3-epoxysqualene = cucurbitadienol.
butanediol metabolic process (GO:0034077)
Namespace: biological_process
Definition: The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
Synonyms: butanediol metabolism; butylene glycol metabolic process; butylene glycol metabolism
butanediol catabolic process (GO:0034078)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
Synonyms: butanediol breakdown; butanediol catabolism; butanediol degradation; butanediol utilization; butylene glycol catabolic process; butylene glycol catabolism
butanediol biosynthetic process (GO:0034079)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol.
Synonyms: butanediol anabolism; butanediol biosynthesis; butanediol fermentation; butanediol formation; butanediol synthesis; butylene glycol biosynthesis; butylene glycol biosynthetic process; glycolytic fermentation to butanediol; pyruvate fermentation to butanediol
CENP-A containing chromatin assembly (GO:0034080)
Namespace: biological_process
Definition: The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
Synonyms: CenH3-containing nucleosome assembly at centromere; CENP-A containing chromatin organization; CENP-A containing nucleosome assembly; CENP-A containing nucleosome assembly at centromere; CENP-A deposition; CENP-A loading; centromere specific nucleosome exchange; centromere-specific histone exchange; centromeric chromatin organization; centromeric DNA replication-independent nucleosome assembly; DNA replication-independent nucleosome assembly at centromere
polyketide synthase complex (GO:0034081)
Namespace: cellular_component
Definition: A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
Synonyms: PKS; PKS complex
type II polyketide synthase complex (GO:0034082)
Namespace: cellular_component
Definition: A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.
Synonyms: type II PKS; type II PKS complex; type II polyketide synthase
type III polyketide synthase complex (GO:0034083)
Namespace: cellular_component
Definition: A polyketide synthase complex that consists of two identical ketosynthase polypeptides.
Synonyms: type III PKS; type III PKS complex; type III polyketide synthase
steryl deacetylase activity (GO:0034084)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.
Synonyms: sterol deacetylase activity; steryl acetyl hydrolase activity
establishment of mitotic sister chromatid cohesion (GO:0034087)
Namespace: biological_process
Definition: The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
maintenance of mitotic sister chromatid cohesion (GO:0034088)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
Synonyms: mitotic cohesion stability
establishment of meiotic sister chromatid cohesion (GO:0034089)
Namespace: biological_process
Definition: The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.
maintenance of meiotic sister chromatid cohesion (GO:0034090)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
regulation of maintenance of sister chromatid cohesion (GO:0034091)
Namespace: biological_process
Definition: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.
negative regulation of maintenance of sister chromatid cohesion (GO:0034092)
Namespace: biological_process
Definition: Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
positive regulation of maintenance of sister chromatid cohesion (GO:0034093)
Namespace: biological_process
Definition: Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
negative regulation of maintenance of meiotic sister chromatid cohesion (GO:0034095)
Namespace: biological_process
Definition: Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
positive regulation of maintenance of meiotic sister chromatid cohesion (GO:0034096)
Namespace: biological_process
Definition: Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
VCP-NPL4-UFD1 AAA ATPase complex (GO:0034098)
Namespace: cellular_component
Definition: A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).
Synonyms: Cdc48p-Npl4p-Ufd1p AAA ATPase complex; p97-Ufd1-Npl4 complex
luminal surveillance complex (GO:0034099)
Namespace: cellular_component
Definition: A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.
erythrocyte homeostasis (GO:0034101)
Namespace: biological_process
Definition: Any process of regulating the production and elimination of erythrocytes within an organism.
Synonyms: RBC homeostasis; red blood cell homeostasis
erythrocyte clearance (GO:0034102)
Namespace: biological_process
Definition: The selective elimination of erythrocytes from the body by autoregulatory mechanisms.
Synonyms: neocytolysis; RBC clearance; red blood cell clearance
Comment: Note that this term is intended for annotation of self-gene products that lead to elimination of erythrocytes without the involvement of a symbiont.
regulation of tissue remodeling (GO:0034103)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of tissue remodeling.
Synonyms: regulation of tissue remodelling
positive regulation of tissue remodeling (GO:0034105)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of tissue remodeling.
Synonyms: positive regulation of tissue remodelling
regulation of erythrocyte clearance (GO:0034106)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of erythrocyte clearance.
Synonyms: regulation of neocytolysis; regulation of RBC clearance; regulation of red blood cell clearance
positive regulation of erythrocyte clearance (GO:0034108)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.
Synonyms: positive regulation of neocytolysis; positive regulation of RBC clearance; positive regulation of red blood cell clearance
homotypic cell-cell adhesion (GO:0034109)
Namespace: biological_process
Definition: The attachment of a cell to a second cell of the identical type via adhesion molecules.
Comment: Note that this term is not synonymous with 'homophilic cell adhesion ; GO:0007156'; the process may occur by homophilic or heterophilic mechanisms.
regulation of homotypic cell-cell adhesion (GO:0034110)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
negative regulation of homotypic cell-cell adhesion (GO:0034111)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.
positive regulation of homotypic cell-cell adhesion (GO:0034112)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.
heterotypic cell-cell adhesion (GO:0034113)
Namespace: biological_process
Definition: The attachment of a cell to a cell of a different type via adhesion molecules.
Comment: Note that this term is not synonymous with 'heterophilic cell adhesion ; GO:0007157'; the process may occur by homophilic or heterophilic mechanisms.
regulation of heterotypic cell-cell adhesion (GO:0034114)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.
negative regulation of heterotypic cell-cell adhesion (GO:0034115)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.
positive regulation of heterotypic cell-cell adhesion (GO:0034116)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
erythrocyte aggregation (GO:0034117)
Namespace: biological_process
Definition: The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.
Synonyms: RBC aggregation; red blood cell aggregation
regulation of erythrocyte aggregation (GO:0034118)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.
Synonyms: regulation of RBC aggregation; regulation of red blood cell aggregation
negative regulation of erythrocyte aggregation (GO:0034119)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.
Synonyms: negative regulation of RBC aggregation; negative regulation of red blood cell aggregation
positive regulation of erythrocyte aggregation (GO:0034120)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.
Synonyms: positive regulation of RBC aggregation; positive regulation of red blood cell aggregation
regulation of toll-like receptor signaling pathway (GO:0034121)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms: regulation of TLR signaling pathway; regulation of toll-like receptor signalling pathway
positive regulation of toll-like receptor signaling pathway (GO:0034123)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms: positive regulation of TLR signaling pathway; positive regulation of toll-like receptor signalling pathway
negative regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034125)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
Synonyms: negative regulation of MyD88-dependent TLR signaling pathway; negative regulation of MyD88-dependent toll-like receptor signalling pathway
positive regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034126)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
Synonyms: positive regulation of MyD88-dependent TLR signaling pathway; positive regulation of MyD88-dependent toll-like receptor signalling pathway
regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034127)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
Synonyms: regulation ofMyD88-independent TLR signaling pathway; regulation ofMyD88-independent toll-like receptor signalling pathway
negative regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034128)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
Synonyms: negative regulation of MyD88-independent TLR signaling pathway; negative regulation of MyD88-independent toll-like receptor signalling pathway
positive regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034129)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
Synonyms: positive regulation of MyD88-independent TLR signaling pathway; positive regulation of MyD88-independent toll-like receptor; positive regulation of MyD88-independent toll-like receptor signalling pathway
toll-like receptor 1 signaling pathway (GO:0034130)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to toll-like receptor 1.
Synonyms: TLR1 signaling pathway; toll-like receptor 1 signalling pathway
negative regulation of toll-like receptor 1 signaling pathway (GO:0034132)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
Synonyms: negative regulation of TLR1 signaling pathway; negative regulation of toll-like receptor 1 signalling pathway
positive regulation of toll-like receptor 1 signaling pathway (GO:0034133)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
Synonyms: positive regulation of TLR1 signaling pathway; positive regulation of toll-like receptor 1 signalling pathway
toll-like receptor 2 signaling pathway (GO:0034134)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to toll-like receptor 2.
Synonyms: TLR2 signaling pathway; toll-like receptor 2 signalling pathway
regulation of toll-like receptor 2 signaling pathway (GO:0034135)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
Synonyms: regulation of TLR2 signaling pathway; regulation of toll-like receptor 2 signalling pathway
negative regulation of toll-like receptor 2 signaling pathway (GO:0034136)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
Synonyms: negative regulation of TLR2 signaling pathway; negative regulation of toll-like receptor 2 signalling pathway
positive regulation of toll-like receptor 2 signaling pathway (GO:0034137)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
Synonyms: positive regulation of TLR2 signaling pathway; positive regulation of toll-like receptor 2 signalling pathway
toll-like receptor 3 signaling pathway (GO:0034138)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3.
Synonyms: TLR3 signaling pathway; toll-like receptor 3 signalling pathway
regulation of toll-like receptor 3 signaling pathway (GO:0034139)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
Synonyms: regulation of TLR3 signaling pathway; regulation of toll-like receptor 3 signalling pathway
negative regulation of toll-like receptor 3 signaling pathway (GO:0034140)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
Synonyms: negative regulation of TLR3 signaling pathway; negative regulation of toll-like receptor 3 signalling pathway
positive regulation of toll-like receptor 3 signaling pathway (GO:0034141)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
Synonyms: positive regulation of TLR3 signaling pathway; positive regulation of toll-like receptor 3 signalling pathway
toll-like receptor 4 signaling pathway (GO:0034142)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to toll-like receptor 4.
Synonyms: TLR4 signaling pathway; toll-like receptor 4 signalling pathway
regulation of toll-like receptor 4 signaling pathway (GO:0034143)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms: regulation of TLR4 signaling pathway; regulation of toll-like receptor 4 signalling pathway
negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
Synonyms: negative regulation of TLR4 signaling pathway; negative regulation of toll-like receptor 4 signalling pathway