LiteFold/GO huggingface dataset:
obsolete protein phosphorylation involved in protein localization to spindle microtubule (GO:1990803)
Namespace: biological_process
Definition: OBSOLETE. Any protein phosphorylation process involved in localizing a protein to the spindle microtubule.
Synonyms: protein amino acid phosphorylation involved in protein localisation in spindle microtubule; protein amino acid phosphorylation involved in protein localisation to spindle microtubule; protein amino acid phosphorylation involved in protein localization in spindle microtubule; protein amino acid phosphorylation involved in protein localization to spindle microtubule; protein phosphorylation involved in protein localisation in spindle microtubule; protein phosphorylation involved in protein localisation to spindle microtubule; protein phosphorylation involved in protein localization in spindle microtubule
Comment: This term has been obsoleted because it represents a GO-CAM model.
central cylinder (GO:1990805)
Namespace: cellular_component
Definition: A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.
ligand-gated ion channel signaling pathway (GO:1990806)
Namespace: biological_process
Definition: The series of molecular signals initiated by activation of a ligand-gated ion channel on the surface of a cell. The pathway begins with binding of an extracellular ligand to a ligand-gated ion channel and ends with a molecular function that directly regulates a downstream cellular process, e.g. transcription.
Synonyms: ligand-gated ion channel signalling pathway
obsolete protein N-acetyltransferase activity (GO:1990807)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of an acetyl group to a nitrogen atom on the amino acid of a protein.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
microtubule anchoring at mitotic spindle pole body (GO:1990810)
Namespace: biological_process
Definition: Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
MWP complex (GO:1990811)
Namespace: cellular_component
Definition: A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.
Synonyms: Msd1-Wdr8-Pkl1 complex
growth cone filopodium (GO:1990812)
Namespace: cellular_component
Definition: A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.
meiotic centromeric cohesion protection in anaphase I (GO:1990813)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation at meiotic anaphase I after cohesin is cleaved by separase along the arm regions.
Synonyms: anaphase cohesion protection; protection of centromeric cohesion during meiotic anaphase I
vacuole-mitochondrion membrane contact site (GO:1990816)
Namespace: cellular_component
Definition: A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.
Synonyms: vacuole and mitochondria patch; vCLAMP
poly(A) RNA polymerase activity (GO:1990817)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
Synonyms: NTP polymerase activity; poly(A) polymerase activity; polynucleotide adenylyltransferase activity; RNA adenylating enzyme; RNA adenyltransferase activity; RNA adenylyltransferase activity
L-arginine transmembrane export from vacuole (GO:1990818)
Namespace: biological_process
Definition: The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.
mating projection actin fusion focus (GO:1990819)
Namespace: cellular_component
Definition: A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
Synonyms: actin fusion focus
response to mitotic DNA integrity checkpoint signaling (GO:1990820)
Namespace: biological_process
Definition: A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.
Synonyms: response to signal involved in mitotic DNA integrity checkpoint
basic amino acid transmembrane transport (GO:1990822)
Namespace: biological_process
Definition: The directed movement of basic amino acids from one side of a membrane to the other.
response to leukemia inhibitory factor (GO:1990823)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
Synonyms: response to CDF; response to cholinergic differentiation factor; response to LIF
obsolete magnesium-dependent protein complex (GO:1990824)
Namespace: cellular_component
Definition: OBSOLETE. A protein complex that depends on magnesium in order for one or more of its components to remain a part of the complex.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
sequence-specific mRNA binding (GO:1990825)
Namespace: molecular_function
Definition: Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
nucleoplasmic periphery of the nuclear pore complex (GO:1990826)
Namespace: cellular_component
Definition: Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.
Synonyms: associated with the nuclear pore
deaminase binding (GO:1990827)
Namespace: molecular_function
Definition: Binding to an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).
hepatocyte dedifferentiation (GO:1990828)
Namespace: biological_process
Definition: The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
C-rich single-stranded DNA binding (GO:1990829)
Namespace: molecular_function
Definition: Binding to C-rich, single-stranded DNA.
Synonyms: C-rich ssDNA binding
cellular response to leukemia inhibitory factor (GO:1990830)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
Synonyms: cellular response to CDF; cellular response to cholinergic differentiation factor
cellular response to carcinoembryonic antigen (GO:1990831)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.
Synonyms: cellular response to pregnancy specific glycoprotein
slow axonal transport (GO:1990832)
Namespace: biological_process
Definition: The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a Slow Component a (SCa) and a Slow Component b (SCb) which differ in transport rates and protein composition.
response to odorant (GO:1990834)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
obsolete insulin-like growth factor production (GO:1990835)
Namespace: biological_process
Definition: OBSOLETE. The appearance of an insulin-like growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IGF production
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
lysosomal matrix (GO:1990836)
Namespace: cellular_component
Definition: A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.
sequence-specific double-stranded DNA binding (GO:1990837)
Namespace: molecular_function
Definition: Binding to double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
Synonyms: sequence-specific dsDNA binding
poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends (GO:1990838)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine.
response to endothelin (GO:1990839)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
response to lectin (GO:1990840)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
Comment: This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.
promoter-specific chromatin binding (GO:1990841)
Namespace: molecular_function
Definition: Binding to a section of chromatin that is associated with gene promoter sequences of DNA.
obsolete response to prenatal stress (GO:1990842)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis in the embryo or fetus during pregnancy.
Synonyms: response to PNS
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
obsolete subsarcolemmal mitochondrion (GO:1990843)
Namespace: cellular_component
Definition: OBSOLETE. A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers.
Synonyms: SS mitochondrion; SSM
Comment: This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.
obsolete interfibrillar mitochondrion (GO:1990844)
Namespace: cellular_component
Definition: OBSOLETE. A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers.
Synonyms: IFM; IMF mitochondrion; intermyofibrillar mitochondrion
Comment: This term was obsoleted because it corresponds to mitochondria of specific cell types and this information should be captured as an extension.
adaptive thermogenesis (GO:1990845)
Namespace: biological_process
Definition: The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.
ribonucleoside-diphosphate reductase inhibitor activity (GO:1990846)
Namespace: molecular_function
Definition: Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.
obsolete peptide pheromone transmembrane export involved in positive regulation of conjugation with cellular fusion (GO:1990847)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.
Comment: This term was obsoleted because it represents a BP in a BP and should be captured with a GO-CAM model
obsolete Positive regulation of removal of reactive oxygen species (GO:1990848)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of removal of reactive oxygen species in a cell.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
vacuolar localization (GO:1990849)
Namespace: biological_process
Definition: Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.
Synonyms: maintenance of vacuolar localization; maintenance of vacuolar location; maintenance of vacuole localization; maintenance of vacuole location
H-gal-GP complex (GO:1990850)
Namespace: cellular_component
Definition: A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.
Synonyms: galactose-containing glycoprotein complex; Haemonchus galactose-containing glycoprotein complex
protein transport along microtubule to spindle pole body (GO:1990852)
Namespace: biological_process
Definition: The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.
vacuole-ER tethering (GO:1990854)
Namespace: biological_process
Definition: The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.
Synonyms: vacuole-endoplasmic reticulum attachment; vacuole-endoplasmic reticulum tethering; vacuole-ER attachment
obsolete myo-inositol import across plasma membrane (GO:1990855)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell across the plasma membrane.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
methionyl-initiator methionine tRNA binding (GO:1990856)
Namespace: molecular_function
Definition: Binding to methionine-initiator methionine tRNA.
Comment: An example of this is eukaryotic initiation factor 2 complex, which binds the methionyl-initiator methionine tRNA during ternary complex formation. The non-acylated tRNA is not bound.
obsolete APC-Fzr1/Mfr1 complex (GO:1990857)
Namespace: cellular_component
Definition: OBSOLETE. An anaphase promoting complex bound to an activator in the Fzr1 (human)/Mfr1 (pombe) family.
Comment: This term was made obsolete because it is too fine-grained for GO.
cellular response to lectin (GO:1990858)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
Comment: This term refers to endogenous (evolved) responses to lectins (endogenous or exogenous), it does not cover the events that happen due to lectin toxicity.
cellular response to endothelin (GO:1990859)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
Pho85-Pho80 CDK-cyclin complex (GO:1990860)
Namespace: cellular_component
Definition: A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
Ubp3-Bre5 deubiquitination complex (GO:1990861)
Namespace: cellular_component
Definition: A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.
Synonyms: Ubp3-Bre5 ubiquitin protease complex
nuclear membrane complex Bqt3-Bqt4 (GO:1990862)
Namespace: cellular_component
Definition: A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.
acinar cell proliferation (GO:1990863)
Namespace: biological_process
Definition: The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).
Synonyms: acinic cell proliferation; acinous cell proliferation
response to growth hormone-releasing hormone (GO:1990864)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.
Synonyms: response to GHRF; response to GRF; response to growth hormone-releasing factor; response to sermorelin; response to somatocrinin; response to somatoliberin; response to somatorelin
obsolete response to sustained hypoxia (GO:1990866)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sustained stimulus indicating lowered oxygen tension.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
response to gastrin (GO:1990867)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
cellular response to chemokine (GO:1990869)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
obsolete protein fibril (GO:1990870)
Namespace: cellular_component
Definition: OBSOLETE. A polymer of proteins that form a fine fiber.
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
Vma12-Vma22 assembly complex (GO:1990871)
Namespace: cellular_component
Definition: A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.
obsolete negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter (GO:1990872)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter.
Synonyms: negative regulation of sterol import by activation of transcription from RNA polymerase II promoter; negative regulation of sterol import by negative regulation of transcription from Pol II promoter; negative regulation of sterol import by stimulation of transcription from RNA polymerase II promoter; negative regulation of sterol import by up regulation of transcription from RNA polymerase II promoter; negative regulation of sterol import by up-regulation of transcription from RNA polymerase II promoter; negative regulation of sterol import by upregulation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by activation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by negative regulation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by stimulation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by up regulation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by up-regulation of transcription from RNA polymerase II promoter; negative regulation of sterol influx by upregulation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by activation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by negative regulation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by stimulation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by up regulation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by up-regulation of transcription from RNA polymerase II promoter; negative regulation of sterol uptake by upregulation of transcription from RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete intrinsic component of plasma membrane of cell tip (GO:1990873)
Namespace: cellular_component
Definition: OBSOLETE. The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
vascular associated smooth muscle cell proliferation (GO:1990874)
Namespace: biological_process
Definition: The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
Synonyms: vascular smooth muscle cell proliferation; VSMC proliferation
nucleoplasmic side of nuclear pore (GO:1990875)
Namespace: cellular_component
Definition: The side of the nuclear pore complex (NPC) that faces the nucleoplasm.
Synonyms: nucleoplasmic side of NPC; nucleoplasmic side of nuclear pore complex; nucleoplasmic side of nucleopore
cytoplasmic side of nuclear pore (GO:1990876)
Namespace: cellular_component
Definition: The side of the nuclear pore complex (NPC) that faces the cytoplasm.
Synonyms: cytoplasmic side of NPC; cytoplasmic side of nuclear pore complex; cytoplasmic side of nucleopore
FNIP-folliculin RagC/D GAP (GO:1990877)
Namespace: cellular_component
Definition: A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains follicular (FLCN) and either follicular interacting protein 1 (FNIP1) or FNIP2.
Synonyms: BFC complex; FLCN-FNIP1 complex; FLCN-FNIP2 complex; FNIP-Folliculin RagC/D GAP complex; Lst4-Lst7 complex
cellular response to gastrin (GO:1990878)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
CST complex (GO:1990879)
Namespace: cellular_component
Definition: A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
Synonyms: Cdc13-Stn1-Ten1 complex; CTC1-OBFC1-TEN1 complex