LiteFold/GO huggingface dataset:
surfactant homeostasis (GO:0043129)
Namespace: biological_process
Definition: Any process involved in the maintenance of a steady-state level of a surface-active agent that maintains the surface tension of a liquid.
Synonyms: regulation of liquid surface tension; regulation of surface tension of a liquid; surfactant activity
ubiquitin binding (GO:0043130)
Namespace: molecular_function
Definition: Binding to ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
erythrocyte enucleation (GO:0043131)
Namespace: biological_process
Definition: The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.
NAD transport (GO:0043132)
Namespace: biological_process
Definition: The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
Synonyms: NAD (oxidized) transport; NAD (reduced) transport; NADH transport; nicotinamide adenine dinucleotide transport; oxidized NAD transport; oxidized nicotinamide adenine dinucleotide transport; reduced NAD transport; reduced nicotinamide adenine dinucleotide transport
regulation of hindgut contraction (GO:0043134)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
sn-glycerol 3-phosphatase activity (GO:0043136)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + sn-glycerol 3-phosphate = glycerol + phosphate.
Synonyms: glycerol-1-phosphatase activity; glycerol-3-phosphatase activity
3'-5' DNA helicase activity (GO:0043138)
Namespace: molecular_function
Definition: Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.
Synonyms: 3' to 5' DNA helicase activity; ATP-dependent 3' to 5' DNA helicase activity; ATP-dependent 3'-5' DNA helicase activity
regulation of translation by machinery localization (GO:0043143)
Namespace: biological_process
Definition: Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.
Synonyms: establishment and maintenance of translational machinery localization; establishment and maintenance of translational protein localization; regulation of translation by machinery localisation; translational machinery localization; translational protein localization
sno(s)RNA processing (GO:0043144)
Namespace: biological_process
Definition: Any process involved in the conversion of a primary snoRNA family RNA transcript into a mature snoRNA (eukaryota) or sRNA (archaea).
sno(s)RNA 3'-end cleavage (GO:0043145)
Namespace: biological_process
Definition: The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.
Synonyms: sno(s)RNA 3' end cleavage; snoRNA 3'-end cleavage; sRNA 3'-end cleavage
stress fiber assembly (GO:0043149)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.
Synonyms: actin cable assembly; actin cable formation; stress fibre biosynthesis; stress fibre formation
DNA synthesis involved in double-strand break repair via homologous recombination (GO:0043150)
Namespace: biological_process
Definition: The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.
Synonyms: DNA synthesis during double-strand break repair via homologous recombination
obsolete DNA synthesis involved in double-strand break repair via single-strand annealing (GO:0043151)
Namespace: biological_process
Definition: OBSOLETE. The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.
Synonyms: DNA synthesis during double-strand break repair via single-strand annealing
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
entrainment of circadian clock by photoperiod (GO:0043153)
Namespace: biological_process
Definition: The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).
Synonyms: photoentrainment of circadian clock
obsolete negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
Synonyms: down regulation of caspase activity; down-regulation of caspase activity; downregulation of caspase activity; inhibition of caspase activation; inhibition of caspase activity; negative regulation of caspase activation; negative regulation of caspase activity
Comment: The reason for obsoletion is that this term represents a GO-CAM model.
negative regulation of photosynthesis, light reaction (GO:0043155)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.
Synonyms: down regulation of photosynthesis, light reaction; down-regulation of photosynthesis, light reaction; downregulation of photosynthesis, light reaction; inhibition of photosynthesis, light reaction
obsolete chromatin remodeling in response to cation stress (GO:0043156)
Namespace: biological_process
Definition: OBSOLETE. Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
Comment: This term was obsoleted because it represents a GO-CAM model.
response to cation stress (GO:0043157)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
heterocyst development (GO:0043158)
Namespace: biological_process
Definition: The cellular developmental process by which a cell becomes a heterocyst, a cell that carries out nitrogen fixation. This process involves changes to the cell wall, expression of nitrogenase and other proteins involved in nitrogen fixation, and degradation of photosystem II, which produces oxygen. This process is known to occur in some cyanobacteria.
Synonyms: heterocyst cell differentiation; heterocyst differentiation; heterocyst formation
acrosomal matrix (GO:0043159)
Namespace: cellular_component
Definition: A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.
acrosomal lumen (GO:0043160)
Namespace: cellular_component
Definition: The volume enclosed within the acrosome membrane.
proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Synonyms: proteasomal pathway; proteasomal processing; proteasomal ubiquitin-dependent protein breakdown; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolism; proteasomal ubiquitin-dependent protein degradation; proteasome pathway
Gram-negative-bacterium-type cell wall biogenesis (GO:0043164)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.
Synonyms: 1-2nm peptidoglycan-based cell wall biogenesis; cell wall anabolism; cell wall assembly; cell wall biosynthetic process; cell wall formation; cell wall synthesis
Gram-negative-bacterium-type cell outer membrane assembly (GO:0043165)
Namespace: biological_process
Definition: The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
Synonyms: cell outer membrane biogenesis
ion binding (GO:0043167)
Namespace: molecular_function
Definition: Binding to an ion, a charged atoms or groups of atoms.
Synonyms: atom binding
cation binding (GO:0043169)
Namespace: molecular_function
Definition: Binding to a cation, a charged atom or group of atoms with a net positive charge.
macromolecule metabolic process (GO:0043170)
Namespace: biological_process
Definition: The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
Synonyms: biopolymer metabolic process; macromolecule metabolism; multicellular organismal macromolecule metabolic process; organismal macromolecule metabolism
peptide catabolic process (GO:0043171)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
Synonyms: peptide breakdown; peptide catabolism; peptide degradation
obsolete ferredoxin biosynthetic process (GO:0043172)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.
Synonyms: ferredoxin anabolism; ferredoxin biosynthesis; ferredoxin formation; ferredoxin synthesis
Comment: This term was made obsolete because it refers to biosynthesis of a protein.
nucleotide salvage (GO:0043173)
Namespace: biological_process
Definition: Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
RNA polymerase core enzyme binding (GO:0043175)
Namespace: molecular_function
Definition: Binding to an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
amine binding (GO:0043176)
Namespace: molecular_function
Definition: Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group.
organic acid binding (GO:0043177)
Namespace: molecular_function
Definition: Binding to an organic acid, any acidic compound containing carbon in covalent linkage.
alcohol binding (GO:0043178)
Namespace: molecular_function
Definition: Binding to an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
rhythmic excitation (GO:0043179)
Namespace: biological_process
Definition: Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.
rhythmic inhibition (GO:0043180)
Namespace: biological_process
Definition: Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.
obsolete vacuolar sequestering (GO:0043181)
Namespace: biological_process
Definition: OBSOLETE. The process of transporting a substance into, and confining within, a vacuole.
Synonyms: retention in vacuole; sequestering in vacuole; sequestration in vacuole; storage in vacuole; vacuolar retention; vacuolar sequestration; vacuolar storage
Comment: The reason for obsoletion is that this term represents a molecular function and not a real GO process.
obsolete vacuolar sequestering of sodium ion (GO:0043182)
Namespace: biological_process
Definition: OBSOLETE. The process of transporting sodium ions into, and confining within, a vacuole.
Synonyms: sequestering of sodium ion (Na+) in vacuole; sequestration of sodium ion (Na+) in vacuole; sodium ion (Na+) retention in vacuole; sodium ion (Na+) storage in vacuole; vacuolar sequestering of sodium ion (Na+); vacuolar sequestration of sodium ion (Na+); vacuolar sodium ion (Na+) retention; vacuolar sodium ion (Na+) storage
Comment: The reason for obsoletion is that this term represents a molecular function and not a real GO process.
vascular endothelial growth factor receptor 1 binding (GO:0043183)
Namespace: molecular_function
Definition: Binding to a vascular endothelial growth factor receptor 1.
Synonyms: Flt-1 binding; VEGF receptor 1 binding; VEGFR 1 binding
vascular endothelial growth factor receptor 2 binding (GO:0043184)
Namespace: molecular_function
Definition: Binding to a vascular endothelial growth factor receptor 2.
Synonyms: Flk-1 binding; KDR binding; kinase domain region binding; VEGF receptor 2 binding; VEGFR 2 binding
vascular endothelial growth factor receptor 3 binding (GO:0043185)
Namespace: molecular_function
Definition: Binding to a vascular endothelial growth factor receptor 3.
Synonyms: fms-like-tyrosine kinase (Flt)-4 binding; VEGF receptor 3 binding; VEGFR 3 binding
P granule (GO:0043186)
Namespace: cellular_component
Definition: A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells of many higher eukaryotes.
Synonyms: germline granule; nuage; polar granule
cell septum edging (GO:0043188)
Namespace: cellular_component
Definition: The cell wall material that surrounds the septum in fungal cells.
H4/H2A histone acetyltransferase complex (GO:0043189)
Namespace: cellular_component
Definition: A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.
Synonyms: H4/H2A HAT complex
ATP-binding cassette (ABC) transporter complex (GO:0043190)
Namespace: cellular_component
Definition: A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
Synonyms: ABC-type efflux permease complex; ABC-type efflux porter complex; ABC-type uptake permease complex; mating pheromone exporter
axon initial segment (GO:0043194)
Namespace: cellular_component
Definition: Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
Synonyms: initial segment
terminal bouton (GO:0043195)
Namespace: cellular_component
Definition: Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
Synonyms: bouton; presynaptic bouton; synaptic bouton; terminal button
varicosity (GO:0043196)
Namespace: cellular_component
Definition: Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
dendritic shaft (GO:0043198)
Namespace: cellular_component
Definition: Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
Synonyms: trunk
sulfate binding (GO:0043199)
Namespace: molecular_function
Definition: Binding to sulfate, SO4(2-), a negatively charged small molecule.
response to amino acid (GO:0043200)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
Synonyms: response to amino acid stimulus
response to L-leucine (GO:0043201)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus.
Synonyms: response to leucine
lysosomal lumen (GO:0043202)
Namespace: cellular_component
Definition: The volume enclosed within the lysosomal membrane.
axon hillock (GO:0043203)
Namespace: cellular_component
Definition: Portion of the neuronal cell soma from which the axon originates.
perikaryon (GO:0043204)
Namespace: cellular_component
Definition: The portion of the cell soma (neuronal cell body) that excludes the nucleus.
Synonyms: cell soma cytoplasm
response to external biotic stimulus (GO:0043207)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
glycosphingolipid binding (GO:0043208)
Namespace: molecular_function
Definition: Binding to glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
myelin sheath (GO:0043209)
Namespace: cellular_component
Definition: An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
Synonyms: astrocyte sheath; oligodendrocyte myelin sheath; Schwann cell myelin sheath
alkanesulfonate binding (GO:0043210)
Namespace: molecular_function
Definition: Binding to alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
ABC-type carbohydrate transporter activity (GO:0043211)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates and their derivatives across a membrane.
Synonyms: ATP-dependent carbohydrate transmembrane transporter activity; ATPase-coupled carbohydrate transmembrane transporter activity; carbohydrate ABC transporter; carbohydrate-transporting ATPase activity
obsolete carbohydrate-exporting ABC transporter activity (GO:0043212)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out).
Synonyms: carbohydrate-exporting ATPase activity
Comment: The reason for obsoletion is that there is no evidence that this function/process/component exists.
bacteriocin transport (GO:0043213)
Namespace: biological_process
Definition: The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
ABC-type bacteriocin transporter activity (GO:0043214)
Namespace: molecular_function
Definition: Enables the transfer of a bacteriocin from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate.
Synonyms: ABC-type bacteriocin transmembrane transporter activity; ATPase-coupled bacteriocin transmembrane transporter activity; bacteriocin ABC transporter
daunorubicin transport (GO:0043215)
Namespace: biological_process
Definition: The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
obsolete ATPase-coupled daunorubicin transmembrane transporter activity (GO:0043216)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out).
Synonyms: ATP-dependent daunorubicin transmembrane transporter activity; daunorubicin ABC transporter; daunorubicin-transporting ATPase activity
Comment: This term was obsoleted because it represents a substrate-specific version of the general term GO:0008559 ATPase-coupled xenobiotic transmembrane transporter activity.
myelin maintenance (GO:0043217)
Namespace: biological_process
Definition: The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.
Synonyms: myelin sheath maintenance
lateral loop (GO:0043219)
Namespace: cellular_component
Definition: Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.
Synonyms: oligodendrocyte paranodal termination; paranodal loop; Schwann cell paranodal termination
Schmidt-Lanterman incisure (GO:0043220)
Namespace: cellular_component
Definition: Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.
Synonyms: Schmidt-Lanterman cleft
SMC family protein binding (GO:0043221)
Namespace: molecular_function
Definition: Binding to a protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.
Synonyms: structural maintenance of chromosomes family protein binding
cytoplasmic SCF ubiquitin ligase complex (GO:0043223)
Namespace: cellular_component
Definition: A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
Synonyms: cytoplasmic cullin complex; cytoplasmic SCF complex; cytoplasmic Skp1/Cul1/F-box protein complex