LiteFold/GO huggingface dataset:
heterochromatin formation (GO:0031507)
Namespace: biological_process
Definition: An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.
Synonyms: chromatin silencing; chromatin-mediated silencing; establishment of chromatin silencing; establishment of heterochromatic silencing; establishment of heterochromatin architecture; establishment of heterochromatin architecture involved in chromatin silencing at centromere outer repeat region; establishment of heterochromatin architecture involved in chromatin silencing at pericentric region; heterochromatic silencing; heterochromatin assembly; heterochromatin assembly involved in chromatin silencing; heterochromatin assembly involved in chromatin silencing at centromere outer repeat region; heterochromatin assembly involved in chromatin silencing at pericentric region; heterochromatin formation involved in chromatin silencing; heterochromatin formation involved in chromatin silencing at centromere outer repeat region; heterochromatin formation involved in chromatin silencing at pericentric region; heterochromatin maintenance; TGS; transcriptional gene silencing
pericentric heterochromatin formation (GO:0031508)
Namespace: biological_process
Definition: The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.
Synonyms: centric heterochromatin formation; centromere chromatin silencing; centromeric heterochromatin biosynthesis; centromeric heterochromatin formation; centromeric silencing; chromatin silencing at centromere; chromatin silencing at centromere outer repeat region; chromatin silencing at pericentric region; heterochromatic silencing at centromere; pericentric heterochromatin assembly
subtelomeric heterochromatin formation (GO:0031509)
Namespace: biological_process
Definition: The compaction of chromatin into heterochromatin at the subtelomeric region.
Synonyms: chromatin silencing at subtelomere; chromatin silencing at telomere; establishment of chromatin silencing at telomere; heterochromatic silencing at subtelomere; heterochromatic silencing at telomere; regulation of chromatin silencing at telomere; regulation of subtelomeric heterochromatin assembly; subtelomere chromatin silencing; subtelomeric heterochromatin assembly; subtelomeric silencing; telomere chromatin silencing; Telomere Position Effect; telomeric heterochromatin assembly; telomeric heterochromatin formation; telomeric silencing
SUMO activating enzyme complex (GO:0031510)
Namespace: cellular_component
Definition: A conserved heterodimeric complex with SUMO activating enzyme activity.
Synonyms: SAE; SUMO E1 activator enzyme complex
Mis6-Sim4 complex (GO:0031511)
Namespace: cellular_component
Definition: A protein complex that forms part of the inner kinetochore, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.
Synonyms: Mcm21; Mis6 centromere subcomplex; Mis6-Mal2-Sim4 centromere complex; Sim4 complex
motile cilium (GO:0031514)
Namespace: cellular_component
Definition: A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
Synonyms: microtubule-based flagellum; motile cilia; motile primary cilia; motile primary cilium; motile secondary cilium; nodal cilium
tRNA (m1A) methyltransferase complex (GO:0031515)
Namespace: cellular_component
Definition: A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.
far-red light photoreceptor activity (GO:0031516)
Namespace: molecular_function
Definition: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.
red light photoreceptor activity (GO:0031517)
Namespace: molecular_function
Definition: The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.
CBF3 complex (GO:0031518)
Namespace: cellular_component
Definition: A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.
PcG protein complex (GO:0031519)
Namespace: cellular_component
Definition: A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
Synonyms: Polycomb Group protein complex
plasma membrane of cell tip (GO:0031520)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding the cell tip.
Synonyms: 'plasma membrane, cell tip'
spitzenkorper (GO:0031521)
Namespace: cellular_component
Definition: Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
cell envelope Sec protein transport complex (GO:0031522)
Namespace: cellular_component
Definition: A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
Synonyms: plasma membrane Sec complex; Sec complex; Sec secretion complex; Sec translocation complex
Comment: Note that this term represents the protein complex involved in transport of proteins across the cytoplasmic membrane. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'type II protein secretion complex ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'endoplasmic reticulum Sec complex ; GO:0031205'.
Myb complex (GO:0031523)
Namespace: cellular_component
Definition: A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.
Synonyms: Myeloblastosis proto-oncogene protein complex
brush border membrane (GO:0031526)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding the brush border.
filopodium membrane (GO:0031527)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding a filopodium.
microvillus membrane (GO:0031528)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding a microvillus.
ruffle organization (GO:0031529)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
Synonyms: ruffle organisation; ruffle organization and biogenesis
gonadotropin-releasing hormone receptor binding (GO:0031530)
Namespace: molecular_function
Definition: Binding to a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
Synonyms: GnRH receptor binding; gonadotrophin-releasing hormone receptor binding
thyrotropin-releasing hormone receptor binding (GO:0031531)
Namespace: molecular_function
Definition: Binding to a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.
Synonyms: thyrotropin releasing hormone receptor binding; thyrotropin-releasing hormone receptor ligand
obsolete actin cytoskeleton reorganization (GO:0031532)
Namespace: biological_process
Definition: OBSOLETE. A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
Synonyms: actin cytoskeleton remodeling; actin cytoskeleton reorganisation
Comment: This term was obsoleted because it represents the same process as actin cytoskeleton organization ; GO:0030036
mRNA capping enzyme complex (GO:0031533)
Namespace: cellular_component
Definition: A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
minus-end directed microtubule sliding (GO:0031534)
Namespace: biological_process
Definition: The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
positive regulation of exit from mitosis (GO:0031536)
Namespace: biological_process
Definition: Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
Synonyms: activation of exit from mitosis; stimulation of exit from mitosis; up regulation of exit from mitosis; up-regulation of exit from mitosis; upregulation of exit from mitosis
regulation of anthocyanin metabolic process (GO:0031537)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
Synonyms: regulation of anthocyanin metabolism
regulation of anthocyanin biosynthetic process (GO:0031540)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
Synonyms: regulation of anthocyanin anabolism; regulation of anthocyanin biosynthesis; regulation of anthocyanin formation; regulation of anthocyanin synthesis
negative regulation of anthocyanin biosynthetic process (GO:0031541)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
Synonyms: down regulation of anthocyanin biosynthetic process; down-regulation of anthocyanin biosynthetic process; downregulation of anthocyanin biosynthetic process; inhibition of anthocyanin biosynthetic process; negative regulation of anthocyanin anabolism; negative regulation of anthocyanin biosynthesis; negative regulation of anthocyanin formation; negative regulation of anthocyanin synthesis
positive regulation of anthocyanin biosynthetic process (GO:0031542)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
Synonyms: activation of anthocyanin biosynthetic process; positive regulation of anthocyanin anabolism; positive regulation of anthocyanin biosynthesis; positive regulation of anthocyanin formation; positive regulation of anthocyanin synthesis; stimulation of anthocyanin biosynthetic process; up regulation of anthocyanin biosynthetic process; up-regulation of anthocyanin biosynthetic process; upregulation of anthocyanin biosynthetic process
peptidyl-proline dioxygenase activity (GO:0031543)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.
Synonyms: proline hydroxylase activity; proline,2-oxoglutarate 4-dioxygenase activity; prolyl 4-hydroxylase activity; prolyl hydroxylase activity
peptidyl-proline 4-dioxygenase activity (GO:0031545)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.
Synonyms: HIF-type prolyl 4-hydroxylase; prolyl 4-hydroxylase
brain-derived neurotrophic factor receptor binding (GO:0031546)
Namespace: molecular_function
Definition: Binding to a brain-derived neurotrophic factor receptor.
Synonyms: BDNF receptor binding; brain-derived neurotrophic factor ligand
brain-derived neurotrophic factor receptor signaling pathway (GO:0031547)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.
Synonyms: BDNF receptor signaling pathway; BDNF signalling pathway; brain-derived neurotrophic factor receptor signalling pathway
negative regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031549)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
Synonyms: down regulation of brain-derived neurotrophic factor receptor signaling pathway; down-regulation of brain-derived neurotrophic factor receptor signaling pathway; downregulation of brain-derived neurotrophic factor receptor signaling pathway; inhibition of brain-derived neurotrophic factor receptor signaling pathway; negative regulation of BDNF receptor signaling pathway; negative regulation of BDNF receptor signalling pathway; negative regulation of brain-derived neurotrophic factor receptor signalling pathway
positive regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031550)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
Synonyms: activation of brain-derived neurotrophic factor receptor signaling pathway; positive regulation of BDNF receptor signaling pathway; positive regulation of BDNF receptor signalling pathway; positive regulation of brain-derived neurotrophic factor receptor signalling pathway; stimulation of brain-derived neurotrophic factor receptor signaling pathway; up regulation of brain-derived neurotrophic factor receptor signaling pathway; up-regulation of brain-derived neurotrophic factor receptor signaling pathway; upregulation of brain-derived neurotrophic factor receptor signaling pathway
obsolete regulation of brain-derived neurotrophic factor-activated receptor activity (GO:0031551)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
Synonyms: regulation of BDNF receptor activity; regulation of brain-derived neurotrophic factor receptor activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of brain-derived neurotrophic factor-activated receptor activity (GO:0031552)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
Synonyms: down regulation of brain-derived neurotrophic factor receptor activity; down-regulation of brain-derived neurotrophic factor receptor activity; downregulation of brain-derived neurotrophic factor receptor activity; inhibition of brain-derived neurotrophic factor receptor activity; negative regulation of BDNF receptor activity; negative regulation of brain-derived neurotrophic factor receptor activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of brain-derived neurotrophic factor-activated receptor activity (GO:0031553)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
Synonyms: activation of brain-derived neurotrophic factor receptor activity; positive regulation of BDNF receptor activity; positive regulation of brain-derived neurotrophic factor receptor activity; stimulation of brain-derived neurotrophic factor receptor activity; up regulation of brain-derived neurotrophic factor receptor activity; up-regulation of brain-derived neurotrophic factor receptor activity; upregulation of brain-derived neurotrophic factor receptor activity
Comment: This term was obsoleted because it represents a molecular function.
regulation of termination of DNA-templated transcription (GO:0031554)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
Synonyms: regulation of DNA-dependent transcription, termination; regulation of DNA-templated transcription, termination; regulation of transcription termination, DNA-dependent; transcription antiterminator activity
transcriptional attenuation (GO:0031555)
Namespace: biological_process
Definition: A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.
obsolete induction of apoptosis in response to chemical stimulus (GO:0031558)
Namespace: biological_process
Definition: OBSOLETE. Any process that directly activates any of the steps required for cell death by apoptosis as a result of a chemical stimulus.
Synonyms: induction of apoptosis in response to chemical stimulus; induction of apoptosis in response to chemical substance
Comment: This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0006915 apoptotic process.
oxidosqualene cyclase activity (GO:0031559)
Namespace: molecular_function
Definition: Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
Synonyms: 2,3-oxidosqualene cyclase activity
Comment: Note that the phrase 'oxidosqualene cyclase' has been used to refer to enzymes that catalyze the reaction represented by 'lanosterol synthase activity ; GO:0000250'.
cellular bud neck polarisome (GO:0031560)
Namespace: cellular_component
Definition: Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
cellular bud tip polarisome (GO:0031561)
Namespace: cellular_component
Definition: Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
hyphal tip polarisome (GO:0031562)
Namespace: cellular_component
Definition: Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
mating projection tip polarisome (GO:0031563)
Namespace: cellular_component
Definition: Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.
transcription antitermination (GO:0031564)
Namespace: biological_process
Definition: A positive regulation of gene expression mechanism that allows RNA polymerase to continue transcription beyond a termination site, thus allowing expression of downstream genes under specific conditions.
Synonyms: transcriptional readthrough
obsolete cytokinesis checkpoint (GO:0031565)
Namespace: biological_process
Definition: OBSOLETE. A mitotic cell cycle checkpoint that detects a defect in cytokinesis and negatively regulates G2/M transition.
Synonyms: contractile ring checkpoint; septin checkpoint
Comment: The reason this term was made obsolete is that the two terms cytokinesis checkpoint (GO:0031565) and cytokinesis after mitosis (GO:0000078) were conflated in meaning.
actomyosin contractile ring maturation (GO:0031566)
Namespace: biological_process
Definition: The cellular process in which the contractile ring cytokinetic ring attains its fully functional state.
Synonyms: actomyosin contractile ring maintenance; cytokinesis, contractile ring maintenance
mitotic cell size control checkpoint signaling (GO:0031567)
Namespace: biological_process
Definition: A signal transduction process that contributes to a cell size control checkpoint during mitosis.
Synonyms: mitotic cell cycle cell size control checkpoint; mitotic cell size control checkpoint; signal transduction involved in cell size control checkpoint
mitotic G1 cell size control checkpoint signaling (GO:0031568)
Namespace: biological_process
Definition: A signal transduction process that contributes to a cell size control checkpoint during the G1/S transition of the cell cycle.
Synonyms: G1 cell size control checkpoint; G1 cell size control checkpoint signalling; mitotic cell cycle G1/S transition size control checkpoint; mitotic G1 cell size control checkpoint; signal transduction involved in G1 cell size control checkpoint; signal transduction involved in mitotic cell cycle G1/S transition size control checkpoint
mitotic G2 cell size control checkpoint signaling (GO:0031569)
Namespace: biological_process
Definition: A signal transduction process that contributes to a cell size control checkpoint prior to the G2/M transition of mitosis.
Synonyms: G2 cell size control checkpoint; G2/M transition size control checkpoint; mitotic cell cycle G2/M transition size control checkpoint; mitotic G2 cell size control checkpoint; signal transduction involved in G2 cell size control checkpoint; signal transduction involved in G2/M transition size control checkpoint; signal transduction involved in mitotic cell cycle G2/M transition size control checkpoint
DNA integrity checkpoint signaling (GO:0031570)
Namespace: biological_process
Definition: A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
Synonyms: DNA integrity checkpoint; signal transduction involved in DNA integrity checkpoint