LiteFold/GO huggingface dataset:
obsolete negative regulation of DNA-binding transcription factor activity (GO:0043433)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
Synonyms: down regulation of transcription factor activity; down-regulation of transcription factor activity; downregulation of transcription factor activity; inhibition of transcription factor activity; negative regulation of androgen receptor activity; negative regulation of DNA binding transcription factor activity; negative regulation of sequence-specific DNA binding transcription factor activity; negative regulation of thyroid hormone receptor activity; negative regulation of transcription factor activity
Comment: The reason for obsoletion is that this term represents a molecular function.
response to corticotropin-releasing hormone (GO:0043435)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
Synonyms: response to corticoliberin stimulus; response to corticotropin-releasing factor stimulus; response to corticotropin-releasing hormone stimulus; response to CRF stimulus; response to CRH stimulus
oxoacid metabolic process (GO:0043436)
Namespace: biological_process
Definition: The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
Synonyms: keto acid metabolic process; keto acid metabolism; ketoacid metabolic process; ketoacid metabolism; oxo acid metabolic process; oxo acid metabolism; oxoacid metabolism
acetoacetic acid metabolic process (GO:0043438)
Namespace: biological_process
Definition: The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.
Synonyms: 3-oxobutanoate metabolic process; 3-oxobutanoate metabolism; 3-oxobutanoic acid metabolic process; 3-oxobutanoic acid metabolism; acetoacetate metabolic process; acetoacetate metabolism; acetoacetic acid metabolism; beta ketobutyric acid metabolic process; beta ketobutyric acid metabolism; beta-ketobutyric acid metabolic process; beta-ketobutyric acid metabolism; diacetic acid metabolic process; diacetic acid metabolism
acetoacetic acid biosynthetic process (GO:0043441)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
Synonyms: acetoacetic acid anabolism; acetoacetic acid biosynthesis; acetoacetic acid formation; acetoacetic acid synthesis
acetoacetic acid catabolic process (GO:0043442)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
Synonyms: acetoacetic acid breakdown; acetoacetic acid catabolism; acetoacetic acid degradation
obsolete acetone metabolic process (GO:0043443)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving acetone, propan-2-one.
Synonyms: 2-propanone metabolic process; 2-propanone metabolism; acetone metabolism; dimethyl ketone metabolic process; dimethyl ketone metabolism; propan-2-one metabolic process; propan-2-one metabolism
Comment: This term was obsoleted because it is not a biological process as defined by GO.
obsolete acetone catabolic process (GO:0043444)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one.
Synonyms: 2-propanone catabolic process; 2-propanone catabolism; acetone breakdown; acetone catabolism; acetone degradation; dimethyl ketone catabolic process; dimethyl ketone catabolism; propan-2-one catabolic process; propan-2-one catabolism
Comment: This term was obsoleted because it is not a biological process as defined by GO.
obsolete alkane metabolic process (GO:0043446)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.
Synonyms: alkane metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
alkane biosynthetic process (GO:0043447)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
Synonyms: alkane anabolism; alkane biosynthesis; alkane formation; alkane synthesis
alkane catabolic process (GO:0043448)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
Synonyms: alkane breakdown; alkane catabolism; alkane degradation
obsolete alkene metabolic process (GO:0043449)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.
Synonyms: alkene metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
alkene biosynthetic process (GO:0043450)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
Synonyms: alkene anabolism; alkene biosynthesis; alkene formation; alkene synthesis
alkene catabolic process (GO:0043451)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
Synonyms: alkene breakdown; alkene catabolism; alkene degradation
obsolete alkyne metabolic process (GO:0043452)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.
Synonyms: alkyne metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
alkyne biosynthetic process (GO:0043453)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.
Synonyms: alkyne anabolism; alkyne biosynthesis; alkyne formation; alkyne synthesis
alkyne catabolic process (GO:0043454)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of an alkyne, any acyclic branched or unbranched hydrocarbon (compound composed only of carbon and hydrogen) having a carbon-carbon triple bond and the general formula CnH2n-2.
Synonyms: alkyne breakdown; alkyne catabolism; alkyne degradation
regulation of secondary metabolic process (GO:0043455)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
Synonyms: regulation of secondary metabolism
regulation of pentose-phosphate shunt (GO:0043456)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.
Synonyms: regulation of pentose phosphate pathway; regulation of pentose phosphate shunt; regulation of pentose-phosphate pathway
regulation of cellular respiration (GO:0043457)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
obsolete response to short exposure to lithium ion (GO:0043459)
Namespace: biological_process
Definition: OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a single or short exposure to a lithium ion stimulus.
Synonyms: response to short exposure to lithium ion
Comment: This term was made obsolete because 'short' is not a quantitative or meaningful measurement of time.
obsolete response to long exposure to lithium ion (GO:0043460)
Namespace: biological_process
Definition: OBSOLETE. A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a long or persistent exposure to a lithium ion stimulus.
Synonyms: response to long exposure to lithium ion
Comment: This term was made obsolete because 'long' is not a quantitative or meaningful measurement of time.
proton-transporting ATP synthase complex assembly (GO:0043461)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.
Synonyms: F-type ATPase complex assembly
regulation of ATP-dependent activity (GO:0043462)
Namespace: biological_process
Definition: Any process that modulates the rate of an ATP-dependent activity.
Synonyms: regulation of adenosinetriphosphatase activity; regulation of ATPase activity
L-malate catabolic process (GO:0043464)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-malate.
Synonyms: L-malate fermentation; malate fermentation; malo-lactate fermentation; malolactate fermentation; malolactic fermentation
Comment: Despite the synonym 'malolactic fermentation', this is not an ATP-generating fermentation process. See MetaCyc:PWY-7685.
regulation of fermentation (GO:0043465)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).
obsolete pyrimidine nucleobase fermentation (GO:0043466)
Namespace: biological_process
Definition: OBSOLETE. The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP.
Synonyms: pyrimidine base fermentation; pyrimidine fermentation
Comment: The reason for obsoletion is that this term is not clearly defined.
regulation of generation of precursor metabolites and energy (GO:0043467)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.
regulation of L-fucose catabolic process (GO:0043468)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of L-fucose.
Synonyms: regulation of fucose catabolic process
regulation of D-xylose catabolic process (GO:0043469)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.
regulation of carbohydrate catabolic process (GO:0043470)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.
obsolete regulation of cellular carbohydrate catabolic process (GO:0043471)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells.
Comment: This term was obsoleted because it is not different from its parent, regulation of carbohydrate catabolic process ; GO:0043470.
IgD binding (GO:0043472)
Namespace: molecular_function
Definition: Binding to an immunoglobulin of a D isotype.
pigmentation (GO:0043473)
Namespace: biological_process
Definition: The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
pigment metabolic process involved in pigmentation (GO:0043474)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.
Synonyms: pigment metabolic process during pigmentation; pigment metabolism during pigmentation
obsolete pigment metabolic process involved in pigment accumulation (GO:0043475)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.
Synonyms: pigment metabolic process during pigment accumulation; pigment metabolism during pigment accumulation
Comment: This term was obsoleted because it is an unnecessary grouping term.
pigment accumulation (GO:0043476)
Namespace: biological_process
Definition: The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.
Synonyms: pigment accumulation in response to external stimulus
pigment biosynthetic process involved in pigment accumulation (GO:0043477)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.
Synonyms: pigment biosynthetic process during pigment accumulation
pigment accumulation in response to UV light (GO:0043478)
Namespace: biological_process
Definition: The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.
pigment accumulation in tissues in response to UV light (GO:0043479)
Namespace: biological_process
Definition: The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.
pigment accumulation in tissues (GO:0043480)
Namespace: biological_process
Definition: The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.
Synonyms: organismal pigment accumulation
anthocyanin accumulation in tissues in response to UV light (GO:0043481)
Namespace: biological_process
Definition: The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.
cellular pigment accumulation (GO:0043482)
Namespace: biological_process
Definition: The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.
regulation of RNA splicing (GO:0043484)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
endosome to pigment granule transport (GO:0043485)
Namespace: biological_process
Definition: The directed movement of substances from endosomes to pigment granules.
regulation of RNA stability (GO:0043487)
Namespace: biological_process
Definition: Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.
regulation of mRNA stability (GO:0043488)
Namespace: biological_process
Definition: Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
RNA stabilization (GO:0043489)
Namespace: biological_process
Definition: Prevention of degradation of RNA molecules.
malate-aspartate shuttle (GO:0043490)
Namespace: biological_process
Definition: The process of transferring reducing equivalents from NADH in the cytosol to the mitochondria via malate. Cytosolic aspartate aminotransferase converts aspartate to oxaloacetate, and cytosolic malate dehydrogenase uses NADH to convert oxaloacetate to malate in the cytosol; the malate-alpha-ketoglutarate carrier then transports the malate into the mitochondria where mitochondrial malate dehydrogenase uses NAD to convert malate back to oxaloacetate; the electrons on the reduced NADH are then available for use in the electron transport chain; mitochondrial aspartate aminotransferase converts oxaloacetate to aspartate, and the glutamate-aspartate carrier transports the aspartate back to the cytosol to complete the cycle.
Synonyms: malate aspartate shuttle; malate/aspartate shuttle; malate:aspartate shuttle
phosphatidylinositol 3-kinase/protein kinase B signal transduction (GO:0043491)
Namespace: biological_process
Definition: An intracellular signaling cassette that starts with phosphatidylinositol 3-kinase (PI3K) activation, production of phosphatidylinositol 3-phosphate (PI3P), activation of PDK1, which recruits and ending with the activation of protein kinase B (PKB, also known as Akt). PI3K is activated by cell surface receptors. Note that PTEN is an inhibitor of the pathway.
Synonyms: AKT signal transduction; AKT signaling; AKT signaling cascade; AKT signalling cascade; phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction; PI3K-PKB/Akt pathway; PI3K/Akt signal transduction; PI3K/PKB signal transduction; PKB signal transduction; PKB signaling; PKB signaling cascade; PKB signalling cascade; protein kinase B signal transduction; protein kinase B signaling; protein kinase B signaling cascade; protein kinase B signalling cascade
viral terminase complex (GO:0043493)
Namespace: cellular_component
Definition: A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.
Synonyms: phage terminase complex; virus terminase complex
CLRC complex (GO:0043494)
Namespace: cellular_component
Definition: An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.
Synonyms: Clr4-Rik1-Cul4 complex; CLRC ubiquitin ligase complex; Rik1 E3 ubiquitin ligase complex; Rik1-E3 ubiquitin ligase complex
protein-membrane adaptor activity (GO:0043495)
Namespace: molecular_function
Definition: The binding activity of a molecule that brings together a protein or a protein complex with a membrane, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain the localization of the protein, protein complex or organelle.
Synonyms: anchoring; protein membrane adaptor; protein membrane adaptor activity; protein membrane anchor
obsolete regulation of protein heterodimerization activity (GO:0043497)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
Comment: This term was obsoleted because it represents a molecular function.
obsolete cell surface binding (GO:0043498)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a component on the surface of a cell.
Synonyms: cell surface binding
Comment: This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.
obsolete eukaryotic cell surface binding (GO:0043499)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a component on the surface of a eukaryotic cell.
Synonyms: eukaryotic cell surface binding
Comment: This term was made obsolete because it is ambiguous and causing confusion, and is an unnecessary grouping term.
muscle adaptation (GO:0043500)
Namespace: biological_process
Definition: A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
Synonyms: muscle plasticity
skeletal muscle adaptation (GO:0043501)
Namespace: biological_process
Definition: Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
Synonyms: skeletal muscle plasticity
regulation of muscle adaptation (GO:0043502)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of muscle adaptation.
Synonyms: regulation of muscle plasticity
skeletal muscle fiber adaptation (GO:0043503)
Namespace: biological_process
Definition: Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
Synonyms: skeletal muscle fiber plasticity; skeletal muscle fibre plasticity; skeletal myofiber plasticity; skeletal myofibre plasticity
mitochondrial DNA repair (GO:0043504)
Namespace: biological_process
Definition: The process of restoring mitochondrial DNA after damage.
CENP-A containing nucleosome (GO:0043505)
Namespace: cellular_component
Definition: A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
Synonyms: CenH3 containing nucleosome; CENP-S-T-W-X; centromere specific nucleosome; centromere-specific nucleosome; centromeric nucleosome; CNP-T-W-S-X complex
regulation of JUN kinase activity (GO:0043506)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of JUN kinase activity.
Synonyms: regulation of JUNK activity
positive regulation of JUN kinase activity (GO:0043507)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
Synonyms: positive regulation of JUNK activity; stimulation of JNK activity; up regulation of JNK activity; up-regulation of JNK activity; upregulation of JNK activity
negative regulation of JUN kinase activity (GO:0043508)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
Synonyms: down regulation of JNK activity; down-regulation of JNK activity; downregulation of JNK activity; inhibition of JNK activity; negative regulation of JUNK activity