LiteFold/GO huggingface dataset:
regulation of asexual sporulation (GO:0034305)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.
Synonyms: regulation of asexual spore formation; regulation of mitotic spore formation; regulation of mitotic sporulation
regulation of ascospore formation (GO:0034307)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.
Synonyms: MAPKKK cascade during sporulation
primary alcohol metabolic process (GO:0034308)
Namespace: biological_process
Definition: The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
Synonyms: monohydric alcohol metabolic process; primary alcohol metabolism
primary alcohol biosynthetic process (GO:0034309)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
Synonyms: monohydric alcohol biosynthetic process; primary alcohol anabolism; primary alcohol biosynthesis; primary alcohol formation; primary alcohol synthesis
primary alcohol catabolic process (GO:0034310)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
Synonyms: monohydric alcohol catabolic process; primary alcohol breakdown; primary alcohol catabolism; primary alcohol degradation
diol metabolic process (GO:0034311)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.
Synonyms: dihydric alcohol metabolic process; diol metabolism
diol biosynthetic process (GO:0034312)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
Synonyms: dihydric alcohol biosynthetic process; diol anabolism; diol biosynthesis; diol formation; diol synthesis
diol catabolic process (GO:0034313)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
Synonyms: dihydric alcohol catabolic process; diol breakdown; diol catabolism; diol degradation
Arp2/3 complex-mediated actin nucleation (GO:0034314)
Namespace: biological_process
Definition: The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
Synonyms: actin filament branch nucleation; branched actin filament nucleation
negative regulation of Arp2/3 complex-mediated actin nucleation (GO:0034316)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
obsolete nicotinate riboside kinase activity (GO:0034317)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + beta-D-ribosylnicotinate = ADP + H+ + nicotinate beta-D-ribonucleotide.
Synonyms: nicotinic acid riboside kinase; ribosylnicotinic acid kinase
Comment: The reason for obsoletion is that this term is equivalent to GO:0061769 ribosylnicotinate kinase activity.
alcohol O-acyltransferase activity (GO:0034318)
Namespace: molecular_function
Definition: Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.
Synonyms: acyl-CoA:alcohol O-acyltransferase activity; acyl-CoA:ethanol O-acyltransferase; acyl-coenzymeA:alcohol O-acyltransferase activity; acyl-coenzymeA:ethanol O-acyltransferase activity; AEATase activity; alcohol acyltransferase activity
obsolete alcohol O-hexanoyltransferase activity (GO:0034320)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.
Comment: This term was obsoleted because it represents a specific substrate of alcohol O-acetyltransferase activity ; GO:0004026.
obsolete alcohol O-decanoyltransferase activity (GO:0034322)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.
Comment: This term was obsoleted because it represents a specific substrate of alcohol O-acetyltransferase activity ; GO:0004026.
obsolete O-butanoyltransferase activity (GO:0034323)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
obsolete O-decanoyltransferase activity (GO:0034325)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
obsolete butanoyltransferase activity (GO:0034326)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete hexanoyltransferase activity (GO:0034327)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete decanoyltransferase activity (GO:0034328)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
cell junction assembly (GO:0034329)
Namespace: biological_process
Definition: A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.
cell junction organization (GO:0034330)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
Synonyms: cell junction assembly and maintenance; cell junction biogenesis; cell junction organisation
cell junction maintenance (GO:0034331)
Namespace: biological_process
Definition: The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
adherens junction organization (GO:0034332)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
Synonyms: adherens junction organisation
adherens junction assembly (GO:0034333)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
Synonyms: adherens junction formation
adherens junction maintenance (GO:0034334)
Namespace: biological_process
Definition: The maintenance of an adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
RNA folding (GO:0034337)
Namespace: biological_process
Definition: The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.
Synonyms: RNA chaperone
short-chain carboxylesterase activity (GO:0034338)
Namespace: molecular_function
Definition: Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.
Synonyms: butyrate esterase activity; butyryl esterase activity; methylbutyrase activity; methylbutyrate esterase activity; monobutyrase activity; propionyl esterase activity; short-chain esterase activity
obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor (GO:0034339)
Namespace: biological_process
Definition: OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to modulate the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
Comment: This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.
response to type I interferon (GO:0034340)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms: response to type I IFN
response to type II interferon (GO:0034341)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
Synonyms: response to gamma-interferon; response to immune interferon; response to interferon-gamma; response to type II IFN
response to type III interferon (GO:0034342)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: response to interferon-lambda; response to type III IFN
type III interferon production (GO:0034343)
Namespace: biological_process
Definition: The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: type III IFN production; type III interferon secretion
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda. This term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
regulation of type III interferon production (GO:0034344)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: regulation of type III IFN production
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.
negative regulation of type III interferon production (GO:0034345)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: down regulation of type III interferon production; down-regulation of type III interferon production; downregulation of type III interferon production; inhibition of type III interferon production; negative regulation of type III IFN production
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.
positive regulation of type III interferon production (GO:0034346)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: activation of type III interferon production; positive regulation of type III IFN production; stimulation of type III interferon production; up regulation of type III interferon production; up-regulation of type III interferon production; upregulation of type III interferon production
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.
type III interferon binding (GO:0034347)
Namespace: molecular_function
Definition: Binding to a type III interferon. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: interferon-lambda binding
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.
glial cell apoptotic process (GO:0034349)
Namespace: biological_process
Definition: Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
Synonyms: apoptosis of glia; apoptosis of glial cells; glia apoptosis; glia programmed cell death by apoptosis; glial cell apoptosis; glial cell programmed cell death by apoptosis; programmed cell death of glia by apoptosis; programmed cell death of glial cells by apoptosis; programmed cell death, glia; programmed cell death, glial cells
regulation of glial cell apoptotic process (GO:0034350)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.
Synonyms: regulation of glial cell apoptosis
negative regulation of glial cell apoptotic process (GO:0034351)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.
Synonyms: down regulation of glial cell apoptosis; down-regulation of glial cell apoptosis; downregulation of glial cell apoptosis; inhibition of glial cell apoptosis; negative regulation of glial cell apoptosis
positive regulation of glial cell apoptotic process (GO:0034352)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.
Synonyms: activation of glial cell apoptosis; positive regulation of glial cell apoptosis; stimulation of glial cell apoptosis; up regulation of glial cell apoptosis; up-regulation of glial cell apoptosis; upregulation of glial cell apoptosis
mRNA 5'-diphosphatase activity (GO:0034353)
Namespace: molecular_function
Definition: Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end.
Synonyms: RNA pyrophosphohydrolase activity
'de novo' NAD+ biosynthetic process from L-tryptophan (GO:0034354)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD+), beginning with the catabolism of L-tryptophan into the precursor quinolinate. NAD+ is a coenzyme that interconverts with its reduced form, NADH, in many redox and catabolic reactions.
Synonyms: 'de novo' NAD biosynthetic process from L-tryptophan; 'de novo' NAD biosynthetic process from tryptophan; de novo NAD biosynthetic process from tryptophan
obsolete NAD biosynthesis via nicotinamide riboside salvage pathway (GO:0034356)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the nicotinamide riboside (NR).
Synonyms: nicotinamide riboside salvage pathway; NR salvage pathway
Comment: This term was obsoleted because it is the unique child class of NAD biosynthetic process via the salvage pathway ; GO:0034355.
photosynthetic membrane (GO:0034357)
Namespace: cellular_component
Definition: A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.
mature chylomicron (GO:0034359)
Namespace: cellular_component
Definition: A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.
chylomicron remnant (GO:0034360)
Namespace: cellular_component
Definition: A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.
very-low-density lipoprotein particle (GO:0034361)
Namespace: cellular_component
Definition: A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
Synonyms: very-low-density lipoprotein complex; VLDL complex; VLDL particle
low-density lipoprotein particle (GO:0034362)
Namespace: cellular_component
Definition: A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.
Synonyms: LDL complex; LDL particle; low-density lipoprotein complex
intermediate-density lipoprotein particle (GO:0034363)
Namespace: cellular_component
Definition: A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).
Synonyms: IDL complex; IDL particle; intermediate-density lipoprotein complex
high-density lipoprotein particle (GO:0034364)
Namespace: cellular_component
Definition: A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
Synonyms: HDL complex; HDL particle; HDL2; HDL3; high-density lipoprotein class complex
discoidal high-density lipoprotein particle (GO:0034365)
Namespace: cellular_component
Definition: A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).
Synonyms: discoidal HDL; nascent HDL; nascent high-density lipoprotein particle
protein-containing complex remodeling (GO:0034367)
Namespace: biological_process
Definition: The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.
Synonyms: macromolecular complex remodeling; macromolecular complex remodelling; protein-containing complex remodelling
protein-lipid complex remodeling (GO:0034368)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.
Synonyms: protein-lipid complex remodelling
plasma lipoprotein particle remodeling (GO:0034369)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms: plasma lipoprotein particle remodelling
triglyceride-rich lipoprotein particle remodeling (GO:0034370)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.
Synonyms: triacylglycerol-rich lipoprotein particle remodeling; triacylglycerol-rich lipoprotein particle remodelling; triglyceride-rich lipoprotein particle remodelling
very-low-density lipoprotein particle remodeling (GO:0034372)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms: VDL formation; VDL remodeling; VDL remodelling; very-low-density lipoprotein particle remodelling
intermediate-density lipoprotein particle remodeling (GO:0034373)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.
Synonyms: IDL remodeling; IDL remodelling; intermediate-density lipoprotein particle formation; intermediate-density lipoprotein particle remodelling
low-density lipoprotein particle remodeling (GO:0034374)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
Synonyms: LDL remodeling; LDL remodelling; low-density lipoprotein particle remodelling; small dense LDL formation; small dense low-density lipoprotein particle formation