LiteFold/GO huggingface dataset:
L-aspartate dehydrogenase [NAD(P)+] activity (GO:0033735)
Namespace: molecular_function
Definition: Catalysis of the reaction: Catalysis of the reaction: L-aspartate + NAD(P)+ + H2O = oxaloacetate + NH4+ + NADPH + H+.
Synonyms: aspartate dehydrogenase [NAD(P)+] activity; aspartate dehydrogenase NAD activity; aspartate dehydrogenase NADP activity; L-aspartate:NAD(P)+ oxidoreductase (deaminating) activity; NAD-dependent aspartate dehydrogenase activity; NADH2-dependent aspartate dehydrogenase activity; NADP+-dependent aspartate dehydrogenase activity
L-lysine 6-oxidase activity (GO:0033736)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + L-lysine + O2 = (S)-2-amino-6-oxohexanoate + H2O2 + NH4+.
Synonyms: L-lysine-epsilon-oxidase activity; L-lysine:oxygen 6-oxidoreductase (deaminating) activity; Lod; LodA; marinocine
obsolete 1-pyrroline dehydrogenase activity (GO:0033737)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
Synonyms: 1-pyrroline:NAD+ oxidoreductase activity; ABALDH; gamma-aminobutyraldehyde dehydrogenase activity; YdcW
Comment: This term was obsoleted because it represents the same reaction as aminobutyraldehyde dehydrogenase activity ; GO:0019145.
methylenetetrahydrofolate reductase (ferredoxin) activity (GO:0033738)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.
Synonyms: 5,10-methylenetetrahydrofolate reductase activity; 5-methyltetrahydrofolate:ferredoxin oxidoreductase activity
preQ1 synthase activity (GO:0033739)
Namespace: molecular_function
Definition: Catalysis of the reaction: 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 2 NADPH + 3 H+.
Synonyms: 7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity; 7-cyano-7-deazaguanine reductase activity; preQ0 oxidoreductase activity; preQ0 reductase activity; QueF; queuine synthase activity; queuine:NADP+ oxidoreductase activity; YkvM
Comment: Note that the reaction occurs in the reverse direction.
hydroxylamine oxidoreductase activity (GO:0033740)
Namespace: molecular_function
Definition: Catalysis of the reaction: hydroxylamine + 3 Fe(III)-[cytochrome c] = nitric oxide + 3 Fe(II)-[cytochrome c] + 3 H+.
adenylyl-sulfate reductase (glutathione) activity (GO:0033741)
Namespace: molecular_function
Definition: Catalysis of the reaction: AMP + glutathione disulfide + H+ + sulfite = 5'-adenylyl sulfate + 2 glutathione.
Synonyms: 5'-adenylylsulfate reductase activity; AMP,sulfite:glutathione-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming) activity; AMP,sulfite:oxidized-glutathione oxidoreductase (adenosine-5'-phosphosulfate-forming) activity; plant-type 5'-adenylylsulfate reductase activity
peptide-methionine (R)-S-oxide reductase activity (GO:0033743)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol.
Synonyms: methionine S-oxide reductase (R-form oxidizing) activity; methionine S-oxide reductase activity; methionine sulfoxide reductase activity; methionine sulfoxide reductase B activity; MsrB; peptide-methionine:thioredoxin-disulfide S-oxidoreductase [methionine (R)-S-oxide-forming] activity; PilB; pMRsr; pMSR; protein-methionine-R-oxide reductase activity; selenoprotein R; SelR; SelX
L-methionine (S)-S-oxide reductase activity (GO:0033744)
Namespace: molecular_function
Definition: Catalysis of the reaction: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol.
Synonyms: acetylmethionine sulfoxide reductase activity; free-methionine (S)-S-oxide reductase activity; fSMsr; L-methionine-(S)-S-oxide reductase activity; L-methionine:oxidized-thioredoxin S-oxidoreductase activity; L-methionine:thioredoxin-disulfide S-oxidoreductase activity; methionine sulfoxide reductase activity; methionine-S-oxide reductase activity; methyl sulfoxide reductase I and II activity
L-methionine (R)-S-oxide reductase activity (GO:0033745)
Namespace: molecular_function
Definition: Catalysis of the reaction: [thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol.
Synonyms: free met-R-(o) reductase activity; free-methionine (R)-S-oxide reductase activity; FRMsr; L-methionine:thioredoxin-disulfide S-oxidoreductase [L-methionine (R)-S-oxide-forming] activity; methionine-R-sulfoxide reductase activity
obsolete versatile peroxidase activity (GO:0033747)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reactions: Reactive Black 5 + hydrogen peroxide = oxidized Reactive Black 5 + 2 H2O, and donor + hydrogen peroxide = oxidized donor + 2 H2O.
Synonyms: hybrid peroxidase activity; polyvalent peroxidase activity; reactive-black-5:hydrogen-peroxide oxidoreductase activity; versatile peroxidase activity; VP
hydrogenase (acceptor) activity (GO:0033748)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2 + A = AH2.
Synonyms: H2 producing hydrogenase activity; hydrogen-lyase activity; hydrogen:(acceptor) oxidoreductase activity; hydrogen:acceptor oxidoreductase activity; hydrogenlyase activity; uptake hydrogenase activity
histone H4R3 demethylase activity (GO:0033749)
Namespace: molecular_function
Definition: Catalysis of the removal of the methyl group from a modified arginine residue at position 3 of the histone H4 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.
Synonyms: histone demethylase activity (H4-R3 specific); histone H4-methyl-arginine-3 demethylase activity; histone H4R3me demethylase activity
Comment: Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
ribosome localization (GO:0033750)
Namespace: biological_process
Definition: A process in which a ribosome is transported to, and/or maintained in, a specific location.
Synonyms: establishment of ribosome localisation; establishment of ribosome localization; ribosome localisation
obsolete linoleate 8R-lipoxygenase (GO:0033751)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.
Synonyms: 5,8-linoleate diol synthase (bifunctional enzyme); 7,8-linoleate diol synthase (bifunctional enzyme); linoleate diol synthase activity
Comment: The reason for obsoletion is because there is no support for the reaction. EC and RHEA mappings have been obsoleted at their source.
acetylacetone-cleaving enzyme activity (GO:0033752)
Namespace: molecular_function
Definition: Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.
Synonyms: acetylacetone dioxygenase activity; acetylacetone-cleaving enzyme; acetylacetone:oxygen oxidoreductase activity; diketone cleaving dioxygenase activity; diketone cleaving enzyme; Dke1
sulfur oxygenase/reductase activity (GO:0033755)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.
Synonyms: SOR; sulfur oxygenase activity; sulfur:oxygen oxidoreductase (hydrogen-sulfide- and sulfite-forming) activity; sulphur oxygenase/reductase activity
Oplophorus-luciferin 2-monooxygenase activity (GO:0033756)
Namespace: molecular_function
Definition: Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.
Synonyms: Oplophorus luciferase activity; Oplophorus-luciferin:oxygen 2-oxidoreductase (decarboxylating) activity
glucoside 3-dehydrogenase activity (GO:0033757)
Namespace: molecular_function
Definition: Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.
Synonyms: D-aldohexopyranoside dehydrogenase; D-aldohexoside:(acceptor) 3-oxidoreductase; D-aldohexoside:acceptor 3-oxidoreductase; D-aldohexoside:cytochrome c oxidoreductase; hexopyranoside-cytochrome c oxidoreductase
clavaminate synthase activity (GO:0033758)
Namespace: molecular_function
Definition: Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.
Synonyms: clavaminate synthase 2 activity; clavaminic acid synthase activity; deoxyamidinoproclavaminate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
flavone synthase activity (GO:0033759)
Namespace: molecular_function
Definition: Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.
Synonyms: flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating) activity; flavone synthase I activity; FNS I
mugineic-acid 3-dioxygenase activity (GO:0033761)
Namespace: molecular_function
Definition: Catalysis of the reaction: mugineate + 2-oxoglutarate + O2 = 3-epihydroxymugineate + CO2 + H+ + succinate. Also converts 2'-deoxymugineate to 3-epihydroxy-2'-deoxymugineate.
Synonyms: IDS2; mugineic acid,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
response to glucagon (GO:0033762)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
Synonyms: response to glucagon stimulus
proline 3-hydroxylase activity (GO:0033763)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.
Synonyms: L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity; P-3-H
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0033764)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
steroid dehydrogenase activity, acting on the CH-CH group of donors (GO:0033765)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.
2-hydroxyquinoline 8-monooxygenase activity (GO:0033766)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + NADH + O2 + quinolin-2-ol = H2O + NAD+ + quinoline-2,8-diol.
Synonyms: 2-oxo-1,2-dihydroquinoline 8-monooxygenase activity; quinolin-2(1H)-one,NADH:oxygen oxidoreductase (8-oxygenating) activity
4-hydroxyacetophenone monooxygenase activity (GO:0033767)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4'-hydroxyacetophenone + H+ + NADPH + O2 = 4-hydroxyphenyl acetate + H2O + NADP+.
Synonyms: (4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming) activity; HAPMO
SUMO-targeted ubiquitin ligase complex (GO:0033768)
Namespace: cellular_component
Definition: A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.
glyceollin synthase activity (GO:0033769)
Namespace: molecular_function
Definition: Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin II or glyceollin III + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin I + NADP+ + 2 H2O.
Synonyms: dimethylallyl-3,6a,9-trihydroxypterocarpan cyclase activity
2-hydroxyisoflavanone synthase activity (GO:0033770)
Namespace: molecular_function
Definition: Catalysis of the reactions: liquiritigenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',7-trihydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase] and (2S)-naringenin + O2 + [reduced NADPH--hemoprotein reductase] = 2,4',5,7-tetrahydroxyisoflavanone + H2O + [oxidized NADPH--hemoprotein reductase].
Synonyms: isoflavonoid synthase
flavanone 2-hydroxylase activity (GO:0033771)
Namespace: molecular_function
Definition: Catalysis of the reaction: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] = a 2-hydroxyflavanone + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
Synonyms: licodione synthase activity
flavonoid 3',5'-hydroxylase activity (GO:0033772)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = a 3',5'-dihydroxyflavanone + 2 H+ + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase].
Synonyms: F3',5'H; F3'5'H; flavanone,NADPH:oxygen oxidoreductase activity
isoflavone 2'-hydroxylase activity (GO:0033773)
Namespace: molecular_function
Definition: Catalysis of the reaction: an isoflavone + O2 + reduced [NADPH-hemoprotein reductase] = a 2'-hydroxyisoflavone + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
Synonyms: CYP Ge-3; CYP81E1; isoflavone 2'-monooxygenase activity
basal labyrinth (GO:0033774)
Namespace: cellular_component
Definition: A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.
deoxysarpagine hydroxylase activity (GO:0033775)
Namespace: molecular_function
Definition: Catalysis of the reaction: 10-deoxysarpagine + H+ + NADPH + O2 = H2O + NADP+ + sarpagine.
Synonyms: 10-deoxysarpagine,NADPH:oxygen oxidoreductase (10-hydroxylating) activity; DOSH
phenylacetone monooxygenase activity (GO:0033776)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP+.
Synonyms: PAMO; phenylacetone,NADPH:oxygen oxidoreductase activity
lithocholate 6beta-hydroxylase activity (GO:0033777)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.
Synonyms: 6beta-hydroxylase activity; CYP3A10; cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity; lithocholate 6beta-monooxygenase activity; lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity
obsolete 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase activity (GO:0033778)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+.
Comment: This term was obsoleted because it represents a specific susbstrate of sterol 12-alpha-hydroxylase activity ; GO:0008397.
obsolete 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase activity (GO:0033779)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H+ + NADPH + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H2O + NADP+.
Comment: This term was obsoleted because it represents a specific susbstrate of sterol 12-alpha-hydroxylase activity ; GO:0008397.
taurochenodeoxycholate 6alpha-hydroxylase activity (GO:0033780)
Namespace: molecular_function
Definition: Catalysis of the reaction: taurochenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] +  = taurohyocholate H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Acts on taurochenodeoxycholate, taurodeoxycholate and less readily on lithocholate and chenodeoxycholate.
Synonyms: CYP3A4; CYP4A21; taurochenodeoxycholate 6alpha-monooxygenase activity; taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating) activity
cholesterol 24-hydroxylase activity (GO:0033781)
Namespace: molecular_function
Definition: Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.
Synonyms: cholesterol 24-monooxygenase activity; cholesterol 24S-hydroxylase activity; cholesterol,NADPH:oxygen oxidoreductase (24-hydroxylating) activity; CYP46; CYP46A1; cytochrome P450 46A1
24S-hydroxycholesterol 7-alpha-hydroxylase activity (GO:0033782)
Namespace: molecular_function
Definition: Catalysis of the reaction: (24S)-hydroxycholesterol + O2 + reduced [NADPH-hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H+ + H2O + oxidized [NADPH-hemoprotein reductase].
Synonyms: 24-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity; 24-hydroxycholesterol 7alpha-hydroxylase activity; 24-hydroxycholesterol 7alpha-monooxygenase activity
25-hydroxycholesterol 7-alpha-hydroxylase activity (GO:0033783)
Namespace: molecular_function
Definition: Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol.
Synonyms: 25-hydroxycholesterol 7alpha-monooxygenase activity; cholest-5-ene-3beta,25-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating) activity; CYP7B1; CYP7B1 oxysterol 7alpha-hydroxylase activity
senecionine N-oxygenase activity (GO:0033784)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + NADPH + O2 + senecionine = H2O + NADP+ + senecionine N-oxide.
Synonyms: senecionine monooxygenase (N-oxide-forming) activity; senecionine,NADPH:oxygen oxidoreductase (N-oxide-forming) activity; SNO
heptose 7-phosphate kinase activity (GO:0033785)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.
Synonyms: D-alpha,beta-D-heptose 7-phosphate 1-kinase activity
heptose-1-phosphate adenylyltransferase activity (GO:0033786)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.
Synonyms: D-beta-D-heptose 1-phosphate adenylyltransferase activity; heptose 1-phosphate adenyltransferase activity
cyanocobalamin reductase (cyanide-eliminating) (NADP+) activity (GO:0033787)
Namespace: molecular_function
Definition: Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP+ = cyanocob(III)alamin + H+ + NADPH.
Synonyms: cob(I)alamin, cyanide:NADP+ oxidoreductase activity; cyanocobalamin reductase (NADPH, cyanide-eliminating) activity; cyanocobalamin reductase (NADPH; CN-eliminating) activity; cyanocobalamin reductase activity; NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity; NADPH:cyanocob(III)alamin oxidoreductase (cyanide-eliminating) activity
leucoanthocyanidin reductase activity (GO:0033788)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.
Synonyms: (2R,3S)-catechin:NADP+ 4-oxidoreductase activity; leucocyanidin reductase activity
phenylacetyl-CoA dehydrogenase activity (GO:0033789)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 1,4-benzoquinone + H2O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.
Synonyms: phenylacetyl-CoA:acceptor oxidoreductase activity; phenylacetyl-CoA:quinone oxidoreductase activity
obsolete hydroxymethylfurfural reductase activity (GO:0033790)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity (GO:0033791)
Namespace: molecular_function
Definition: Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.
Synonyms: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA:acceptor 24-oxidoreductase (24R-hydroxylating) activity; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate 24-hydroxylase activity; 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase activity; THC-CoA oxidase activity; THCA-CoA oxidase activity; trihydroxycoprostanoyl-CoA oxidase activity
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity (GO:0033792)
Namespace: molecular_function
Definition: Catalysis of the reactions: a 3alpha-hydroxy bile acid CoA + NAD+ = a 3-oxo bile acid CoA + H+ + NADH.
Synonyms: 7alpha-dehydroxylase activity; bile acid 7-dehydroxylase activity; bile-acid 7alpha-dehydroxylase activity; cholate 7alpha-dehydroxylase activity
Comment: Note that this was originally described as bile acid 7-dehydroxylase (PubMed:3549693). In fact, the 7-dehydroxylation process is catalyzed by multiple enzymes.
aureusidin synthase activity (GO:0033793)
Namespace: molecular_function
Definition: Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = aureusidin 6-O-beta-glucoside + H2O, 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H+ + O2 = 2 aureusidin 6-O-beta-glucoside + 2 H2O, and 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H+ + O2 = bracteatin 6-O-beta-glucoside + H2O. This activity consists of two separate chemical transformations: 3-hydroxylation and oxidative cyclization (2',-dehydrogenation).
Synonyms: 2',4,4',6'-tetrahydroxychalcone:oxygen oxidoreductase activity
betaine reductase activity (GO:0033795)
Namespace: molecular_function
Definition: Catalysis of the reaction: [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H+ + phosphate.
Synonyms: acetyl-phosphate trimethylamine:thioredoxin disulfide oxidoreductase (N,N,N-trimethylglycine-forming) activity
sulfur reductase activity (GO:0033796)
Namespace: molecular_function
Definition: Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide, H2 + n sulfur = H+ + hydrogen sulfide + (n-1) sulfur.
Synonyms: (donor):sulfur oxidoreductase activity; sulphur reductase activity
selenate reductase activity (GO:0033797)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 e(-) + 2 H+ + selenate = H2O + selenite.
Synonyms: selenite:reduced acceptor oxidoreductase activity
thyroxine 5-deiodinase activity (GO:0033798)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + acceptor-H2.
Synonyms: acceptor:3,3',5'-triiodo-L-thyronine oxidoreductase (iodinating) activity; diiodothyronine 5'-deiodinase activity; inner ring-deiodinating pathway; iodothyronine 5-deiodinase activity; iodothyronine inner ring monodeiodinase activity; type III iodothyronine deiodinase activity
myricetin 3'-O-methyltransferase activity (GO:0033799)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.
Synonyms: CrCOMT2; flavonoid 3',5'-O-dimethyltransferase activity; myricetin 3-O-methyltransferase activity; S-adenosyl-L-methionine:myricetin O-methyltransferase activity
isoflavone 7-O-methyltransferase activity (GO:0033800)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.
Synonyms: S-adenosyl-L-methionine:hydroxyisoflavone 7-O-methyltransferase activity
vitexin 2''-O-rhamnoside 7-O-methyltransferase activity (GO:0033801)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.
Synonyms: S-adenosyl-L-methionine:vitexin-2''-O-beta-L-rhamnoside 7-O-methyltransferase activity