LiteFold/GO huggingface dataset:
regulation of heterochromatin organization (GO:0120261)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, extent or location of heterochromatin organization.
negative regulation of heterochromatin organization (GO:0120262)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization.
Synonyms: down regulation of heterochromatin organization; down-regulation of heterochromatin organization; downregulation of heterochromatin organization; inhibition of heterochromatin organization
positive regulation of heterochromatin organization (GO:0120263)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of heterochromatin organization.
Synonyms: activation of heterochromatin organization; stimulation of heterochromatin organization; up regulation of heterochromatin organization; up-regulation of heterochromatin organization; upregulation of heterochromatin organization
regulation of chromosome attachment to the nuclear envelope (GO:0120264)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, extent or location of chromosome attachment to the nuclear envelope.
negative regulation of chromosome attachment to the nuclear envelope (GO:0120265)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chromosome attachment to the nuclear envelope.
Synonyms: down regulation of chromosome attachment to the nuclear envelope; down-regulation of chromosome attachment to the nuclear envelope; downregulation of chromosome attachment to the nuclear envelope; inhibition of chromosome attachment to the nuclear envelope
positive regulation of chromosome attachment to the nuclear envelope (GO:0120266)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.
Synonyms: activation of chromosome attachment to the nuclear envelope; stimulation of chromosome attachment to the nuclear envelope; up regulation of chromosome attachment to the nuclear envelope; up-regulation of chromosome attachment to the nuclear envelope; upregulation of chromosome attachment to the nuclear envelope
pellicular membrane (GO:0120267)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding the pellicle, a structure enclosing some parasite cells such as certain apicomplexa and Euglenozoa. These membranes are associated with an infrastructure of microtubules, microfilaments, and other organelles.
Synonyms: pellicle membrane; pellicular plasma membrane
Comment: This sub-domain of the plasma membrane excludes the ciliary and ciliary pocket membranes.
paraflagellar rod assembly (GO:0120268)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a paraflagellar rod, a large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme.
Synonyms: paraflagellar rod biogenesis; paraflagellar rod formation; PFR assembly
ciliary centrin arm (GO:0120269)
Namespace: cellular_component
Definition: A rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.
regulation of nuclear mRNA surveillance of meiosis-specific transcripts (GO:0120270)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
Synonyms: regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
negative regulation of nuclear mRNA surveillance of meiosis-specific transcripts (GO:0120271)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
Synonyms: negative regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
positive regulation of nuclear mRNA surveillance of meiosis-specific transcripts (GO:0120272)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
Synonyms: positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
ciliary centrin arm assembly (GO:0120273)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of macromolecules to form a ciliary centrin arm, a rod-shaped protein complex containing Centrin4 protein that flanks the flagellum attachment zone (FAZ) filament and the quartet microtubules.
Synonyms: ciliary centrin arm formation
virus coreceptor activity (GO:0120274)
Namespace: molecular_function
Definition: Combining with a virus component, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
Synonyms: viral coreceptor activity
cerebral blood circulation (GO:0120275)
Namespace: biological_process
Definition: The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products.
Synonyms: cerebrum blood circulation; telencephelon blood circulation
positive regulation of cerebral blood circulation (GO:0120277)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cerebral blood circulation.
Synonyms: activation of cerebral blood circulation; positive regulation of cerebrum blood circulation; positive regulation of telencephalon blood circulation; up regulation of cerebral blood circulation; up-regulation of cerebral blood circulation; upregulation of cerebral blood circulation
negative regulation of cerebral blood circulation (GO:0120278)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.
Synonyms: down regulation of cerebral blood circulation; down-regulation of cerebral blood circulation; downregulation of cerebral blood circulation; inhibition of cerebral blood circulation; negative regulation of cerebrum blood circulation; negative regulation of telencephalon blood circulation
Z granule (GO:0120279)
Namespace: cellular_component
Definition: A small cytoplasmic, non-membranous RNA/protein complex aggregate in the primordial germ cells that are distinct from, but colocalize with or are adjacent to, P granules and mutator foci and are associated with RNA metabolism. Z granules have been observed in C. elegans.
Synonyms: germline granule
ciliary pro-basal body (GO:0120280)
Namespace: cellular_component
Definition: The cilary pro-basal body is an immature, partially assembled form of a ciliary basal body found next to the basal body of a cilium. Pro-basal bodies are not capable of nucleating a cilium. As the cell progresses through the cell cycle, continuing assembly will convert the pro-basal body into a mature basal body that is capable of nucleating a cilium.
Synonyms: flagellar pro-basal body; flagellar probasal body; pro-basal body; pro-centriole; probasal body
Comment: Pro-basal bodies are distinct from basal bodies as they are not at the base of a cilium and are not capable of nucleating a cilium. While immature, they contain some structures in common with the mature basal body and also may contain proteins unique to the immature state. Note that cilia and eukaryotic flagella are deemed to be equivalent. In many eukaryotic cells, 'ciliary basal body' (GO:0036064) and 'centriole' (GO:0005814) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component. In other eukaryotic cells, centrioles are not involved in cell division but only in cilium assembly, which is thought to be the ancestral role of the centriole/basal body.
autolysosome membrane (GO:0120281)
Namespace: cellular_component
Definition: A lipid bilayer that surrounds an autolysosome, a single-membrane-bounded vesicle in which endogenous cellular material is degraded.
autolysosome lumen (GO:0120282)
Namespace: cellular_component
Definition: The volume that is enclosed within the autolysosome single-membrane.
protein serine/threonine kinase binding (GO:0120283)
Namespace: molecular_function
Definition: Binding to a protein serine/threonine kinase.
tryptophan binding (GO:0120284)
Namespace: molecular_function
Definition: Binding to 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms: Trp binding
tyrosine sensor activity (GO:0120285)
Namespace: molecular_function
Definition: Binding to and responding, e.g. by conformational change, to changes in the cellular level of tyrosine.
Synonyms: tyrosine sensing activity
tryptophan sensor activity (GO:0120286)
Namespace: molecular_function
Definition: Binding to and responding, e.g. by conformational change, to changes in the cellular level of tryptophan.
Synonyms: tryptophan sensing activity
obsolete regulation of aspartic endopeptidase activity, intramembrane cleaving (GO:0120287)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of aspartic endopeptidase activity, intramembrane cleaving (GO:0120288)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of aspartic endopeptidase activity, intramembrane cleaving (GO:0120289)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of intramembrane cleaving aspartic-type endopeptidase activity.
Comment: This term was obsoleted because it represents a molecular function.
stalled replication fork localization to nuclear periphery (GO:0120290)
Namespace: biological_process
Definition: A cellular localization process where a DNA replication fork that has stalled is signaled to relocate and anchor to the nuclear periphery for the time necessary to complete recombination-dependent replication.
Synonyms: stalled replication fork localization to nuclear periphery involved in replication fork processing
negative regulation of mitotic recombination-dependent replication fork processing (GO:0120291)
Namespace: biological_process
Definition: Any process that inhibits or decreases the rate of mitotic recombination-dependent replication fork processing. Suppression of recombination at replication forks is necessary to prevent template switching.
Synonyms: maintenance of template fidelity during replication fork processing; negative regulation of mitotic recombination involved in replication fork processing; negative regulation of template switch recombination involved in replication fork processing; suppression of template switching during replication fork processing
positive regulation of mitotic recombination-dependent replication fork processing (GO:0120292)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.
Synonyms: positive regulation of homologous recombination dependent replication fork recovery; positive regulation of mitotic recombination involved in replication fork processing; positive regulation of recombination-dependent DNA replication
dynein axonemal particle (GO:0120293)
Namespace: cellular_component
Definition: An aggregation of axonemal dyneins, their specific assembly factors, and broadly-acting chaperones that is located in the cytoplasm.
Synonyms: DynAP
peptide serotonyltransferase activity (GO:0120294)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-glutaminyl-[protein] + serotonin = 5-serotonyl-L-glutamyl-[protein] + NH4+.
histone serotonyltransferase activity (GO:0120295)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-glutaminyl-[histone] + serotonin = 5-serotonyl-L-glutamyl-[histone] + NH4+.
peptide dopaminyltransferase activity (GO:0120296)
Namespace: molecular_function
Definition: Catalysis of the reaction: dopamine + L-glutaminyl-[protein] = 5-dopaminyl-L-glutamyl-[protein] + NH4+.
histone dopaminyltransferase activity (GO:0120297)
Namespace: molecular_function
Definition: Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4+.
peptide noradrenalinyltransferase activity (GO:0120298)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4+.
peptide histaminyltransferase activity (GO:0120299)
Namespace: molecular_function
Definition: Catalysis of the reaction: histamine + L-glutaminyl-[protein] = 5-histaminyl-L-glutamyl-[protein].
histone lactyltransferase (CoA-dependent) activity (GO:0120301)
Namespace: molecular_function
Definition: Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[histone].
Synonyms: histone lactyltransferase (CoA dependent) activity; histone lactyltransferase activity; histone lactyltransferase activity (CoA dependent)
background adaptation (GO:0120302)
Namespace: biological_process
Definition: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity.
visually-mediated background adaptation (GO:0120303)
Namespace: biological_process
Definition: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by melanopsin-expressing eye cells.
integument-mediated background adaptation (GO:0120304)
Namespace: biological_process
Definition: Any process in which an organism changes its pigmentation (lightening in response to a brighter environment or darkening in response to a dimmer environment) in response to a change in light intensity detected by light sensitive cells in the integument.
regulation of pigmentation (GO:0120305)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.
Hechtian strand (GO:0120307)
Namespace: cellular_component
Definition: An extended membranous thread which firmly connects the plasma membrane to the cell wall during plasmolysis such that the plasma membrane does not separate from the cell wall completely.
axonemal outer doublet assembly (GO:0120308)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an axonemal outer doublet, a part of an axoneme consisting of a doublet microtubule.
Synonyms: axonemal outer doublet biogenesis; axonemal outer doublet formation; axonemal outer doublet morphogenesis; axoneme outer doublet assembly; outer doublet assembly; outer-doublet microtubule assembly
cilium attachment to cell body (GO:0120309)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the lateral attachment of the cilium to the cell body via the flagellar attachment zone in some trypanosomatid species.
Synonyms: cilial attachment to cell body; ciliary attachment to cell body; flagellar attachment to cell body; flagellum attachment to cell body
amastigogenesis (GO:0120310)
Namespace: biological_process
Definition: The morphological, biochemical and genetic changes that induce the differentiation of metacyclic parasites into amastigotes in some of the Trypanosomatidae species such as Leishmania parasites and Trypanosoma cruzi. This process occurs inside the cells of the mammalian hosts, particularly in macrophages and other phagocytic cells for Leishmania parasites.
ciliary pro-basal body maturation (GO:0120311)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the conversion of an immature and partially assembled ciliary pro-basal body into a mature basal body that is capable of nucleating a cilium.
Synonyms: flagellar pro-basal body maturation; flagellar probasal body maturation; pro-basal body maturation
negative regulation of oocyte karyosome formation (GO:0120314)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
positive regulation of oocyte karyosome formation (GO:0120315)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
sperm flagellum assembly (GO:0120316)
Namespace: biological_process
Definition: The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium).
sperm mitochondrial sheath assembly (GO:0120317)
Namespace: biological_process
Definition: The assembly and organization of the sperm mitochondrial sheath, the tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
long-chain fatty acid omega-1 hydroxylase activity (GO:0120319)
Namespace: molecular_function
Definition: Catalysis of the reaction: an (omega-1)-ethyl long-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: cytochrome P450 fatty acid omega-1 hydroxylase activity
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
lateral pseudopodium retraction (GO:0120320)
Namespace: biological_process
Definition: The myosin-based contraction and retraction of a lateral pseudopodium.
Synonyms: lateral pseudopodium suppression
nuclear envelope adjacent to nuclear pore complex (GO:0120321)
Namespace: cellular_component
Definition: The region of the nuclear envelope situated in close proximity to a nuclear pore complex.
Synonyms: associated with the nuclear pore; nuclear envelope adjacent to NPC; nuclear envelope periphery of the nuclear pore complex
lipid modification by small protein conjugation (GO:0120322)
Namespace: biological_process
Definition: A lipid modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target lipid.
lipid ubiquitination (GO:0120323)
Namespace: biological_process
Definition: The process in which one or more ubiquitin groups are added to a lipid.
procyclogenesis (GO:0120324)
Namespace: biological_process
Definition: The morphological, biochemical and genetic changes that induce the differentiation of bloodstream form trypomastigotes into procyclic trypomastigotes in some of the Trypanosomatidae species such as Trypanosoma brucei. This process occurs inside the midgut of the tsetse fly vectors in T. brucei.
NuRD complex binding (GO:0120325)
Namespace: molecular_function
Definition: Binding to a NuRD complex.
appressorium-mediated entry into host (GO:0120326)
Namespace: biological_process
Definition: Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: appressorium-mediated host invasion; appressorium-mediated host penetration; appressorium-mediated invasion into host; appressorium-mediated penetration into host
telopode (GO:0120327)
Namespace: cellular_component
Definition: A telopode is a plasma membrane bounded cell projection that is present on a telocyte and is tens to hundreds of microns long. Telopodes form a labyrinthine system communicating through gap junctions.
ATP-dependent DNA (cytosine-5-)-methyltransferase activity (GO:0120328)
Namespace: molecular_function
Definition: Catalytic activity that acts to transfer a methyl group to a DNA molecule, driven by ATP hydrolysis.
protein localization to centriolar satellite (GO:0120329)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within a centriolar satellite.
Synonyms: protein localisation to centriolar satellite
host-mediated modulation of oral microbiota composition (GO:0120332)
Namespace: biological_process
Definition: The biological process involved in maintaining the steady-state number of cells within a population of free-living cells, such as the bacteria, in the mouth.
Synonyms: host-induced regulation of oral microbiota composition; host-mediated regulation of oral microbiota composition
radial spoke 1 (GO:0120333)
Namespace: cellular_component
Definition: The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is most proximal to the base of the cilium. Radial spoke 1 (RS1), similarly to radial spoke 2, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS1 is connected to the tail of the inner dynein arm a/d.
Synonyms: RS1
radial spoke 2 (GO:0120334)
Namespace: cellular_component
Definition: The radial spoke of each group of radial spokes, whether grouped as triplets or doublets, that is immediately distal to radial spoke 1 (RS1). Radial spoke 2 (RS2), similarly to RS1, is comprised of four domains: 1) a very short base anchored to the A microtubule, 2) an elongaged stalk, 3) a bifurcated neck, and 4) an orthogonal head. The base of RS2 is connected to the tail of the inner dynein arm c.
Synonyms: RS2
radial spoke 3 (GO:0120335)
Namespace: cellular_component
Definition: Radial spoke 3 (RS3), when present, is the most distal of each group of radial spokes, whether grouped as triplets or doublets. RS3 has significantly different morphology and protein composition than RS1 and RS2 and also extends at a slant from the microtubule doublet, rather than perpendicularly like RS1 and RS2. In some organisms (e.g. Chlamydomonas and Sarcophaga bullata), RS3 is represented only as a stump attached to the A-microtubule lacking the rest of the stalk structure and entirely lacking the head structure.
Synonyms: RS3