LiteFold/GO huggingface dataset:
positive regulation of acute inflammatory response to antigenic stimulus (GO:0002866)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
Synonyms: activation of acute inflammatory response to antigenic stimulus; stimulation of acute inflammatory response to antigenic stimulus; up regulation of acute inflammatory response to antigenic stimulus; up-regulation of acute inflammatory response to antigenic stimulus; upregulation of acute inflammatory response to antigenic stimulus
regulation of B cell deletion (GO:0002867)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of B cell deletion.
Synonyms: regulation of B lymphocyte deletion; regulation of B-cell deletion; regulation of B-lymphocyte deletion
negative regulation of B cell deletion (GO:0002868)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.
Synonyms: down regulation of B cell deletion; down-regulation of B cell deletion; downregulation of B cell deletion; inhibition of B cell deletion; negative regulation of B lymphocyte deletion; negative regulation of B-cell deletion; negative regulation of B-lymphocyte deletion
positive regulation of B cell deletion (GO:0002869)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of B cell deletion.
Synonyms: activation of B cell deletion; positive regulation of B lymphocyte deletion; positive regulation of B-cell deletion; positive regulation of B-lymphocyte deletion; stimulation of B cell deletion; up regulation of B cell deletion; up-regulation of B cell deletion; upregulation of B cell deletion
T cell anergy (GO:0002870)
Namespace: biological_process
Definition: Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
Synonyms: T lymphocyte anergy; T-cell anergy; T-lymphocyte anergy
regulation of natural killer cell tolerance induction (GO:0002871)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.
Synonyms: regulation of NK cell tolerance induction
regulation of chronic inflammatory response to antigenic stimulus (GO:0002874)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
negative regulation of chronic inflammatory response to antigenic stimulus (GO:0002875)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
Synonyms: down regulation of chronic inflammatory response to antigenic stimulus; down-regulation of chronic inflammatory response to antigenic stimulus; downregulation of chronic inflammatory response to antigenic stimulus; inhibition of chronic inflammatory response to antigenic stimulus
positive regulation of chronic inflammatory response to antigenic stimulus (GO:0002876)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
Synonyms: activation of chronic inflammatory response to antigenic stimulus; stimulation of chronic inflammatory response to antigenic stimulus; up regulation of chronic inflammatory response to antigenic stimulus; up-regulation of chronic inflammatory response to antigenic stimulus; upregulation of chronic inflammatory response to antigenic stimulus
regulation of acute inflammatory response to non-antigenic stimulus (GO:0002877)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
negative regulation of acute inflammatory response to non-antigenic stimulus (GO:0002878)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
Synonyms: down regulation of acute inflammatory response to non-antigenic stimulus; down-regulation of acute inflammatory response to non-antigenic stimulus; downregulation of acute inflammatory response to non-antigenic stimulus; inhibition of acute inflammatory response to non-antigenic stimulus
positive regulation of acute inflammatory response to non-antigenic stimulus (GO:0002879)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
Synonyms: activation of acute inflammatory response to non-antigenic stimulus; stimulation of acute inflammatory response to non-antigenic stimulus; up regulation of acute inflammatory response to non-antigenic stimulus; up-regulation of acute inflammatory response to non-antigenic stimulus; upregulation of acute inflammatory response to non-antigenic stimulus
regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002880)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
negative regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002881)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
Synonyms: down regulation of chronic inflammatory response to non-antigenic stimulus; down-regulation of chronic inflammatory response to non-antigenic stimulus; downregulation of chronic inflammatory response to non-antigenic stimulus; inhibition of chronic inflammatory response to non-antigenic stimulus
positive regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002882)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
Synonyms: activation of chronic inflammatory response to non-antigenic stimulus; stimulation of chronic inflammatory response to non-antigenic stimulus; up regulation of chronic inflammatory response to non-antigenic stimulus; up-regulation of chronic inflammatory response to non-antigenic stimulus; upregulation of chronic inflammatory response to non-antigenic stimulus
regulation of hypersensitivity (GO:0002883)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of hypersensitivity.
positive regulation of hypersensitivity (GO:0002885)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
Synonyms: activation of hypersensitivity; stimulation of hypersensitivity; up regulation of hypersensitivity; up-regulation of hypersensitivity; upregulation of hypersensitivity
regulation of myeloid leukocyte mediated immunity (GO:0002886)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
negative regulation of myeloid leukocyte mediated immunity (GO:0002887)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
Synonyms: down regulation of myeloid leukocyte mediated immunity; down-regulation of myeloid leukocyte mediated immunity; downregulation of myeloid leukocyte mediated immunity; inhibition of myeloid leukocyte mediated immunity
positive regulation of myeloid leukocyte mediated immunity (GO:0002888)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
Synonyms: activation of myeloid leukocyte mediated immunity; stimulation of myeloid leukocyte mediated immunity; up regulation of myeloid leukocyte mediated immunity; up-regulation of myeloid leukocyte mediated immunity; upregulation of myeloid leukocyte mediated immunity
regulation of immunoglobulin mediated immune response (GO:0002889)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
negative regulation of immunoglobulin mediated immune response (GO:0002890)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
Synonyms: down regulation of immunoglobulin mediated immune response; down-regulation of immunoglobulin mediated immune response; downregulation of immunoglobulin mediated immune response; inhibition of immunoglobulin mediated immune response
positive regulation of immunoglobulin mediated immune response (GO:0002891)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
Synonyms: activation of immunoglobulin mediated immune response; stimulation of immunoglobulin mediated immune response; up regulation of immunoglobulin mediated immune response; up-regulation of immunoglobulin mediated immune response; upregulation of immunoglobulin mediated immune response
negative regulation of type II hypersensitivity (GO:0002893)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.
Synonyms: down regulation of type II hypersensitivity; down-regulation of type II hypersensitivity; downregulation of type II hypersensitivity; inhibition of type II hypersensitivity
positive regulation of type II hypersensitivity (GO:0002894)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
Synonyms: activation of type II hypersensitivity; stimulation of type II hypersensitivity; up regulation of type II hypersensitivity; up-regulation of type II hypersensitivity; upregulation of type II hypersensitivity
regulation of central B cell tolerance induction (GO:0002895)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.
negative regulation of central B cell tolerance induction (GO:0002896)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.
Synonyms: down regulation of central B cell tolerance induction; down-regulation of central B cell tolerance induction; downregulation of central B cell tolerance induction; inhibition of central B cell tolerance induction
positive regulation of central B cell tolerance induction (GO:0002897)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
Synonyms: activation of central B cell tolerance induction; stimulation of central B cell tolerance induction; up regulation of central B cell tolerance induction; up-regulation of central B cell tolerance induction; upregulation of central B cell tolerance induction
negative regulation of central B cell deletion (GO:0002899)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.
Synonyms: down regulation of central B cell deletion; down-regulation of central B cell deletion; downregulation of central B cell deletion; inhibition of central B cell deletion
positive regulation of central B cell deletion (GO:0002900)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of central B cell deletion.
Synonyms: activation of central B cell deletion; stimulation of central B cell deletion; up regulation of central B cell deletion; up-regulation of central B cell deletion; upregulation of central B cell deletion
mature B cell apoptotic process (GO:0002901)
Namespace: biological_process
Definition: Any apoptotic process in a B cell that is mature, having left the bone marrow.
Synonyms: apoptosis of mature B cells; apoptosis of mature B lymphocytes; apoptosis of mature B-cells; apoptosis of mature B-lymphocytes; mature B cell apoptosis; mature B cell programmed cell death by apoptosis; mature B lymphocyte apoptosis; mature B lymphocyte programmed cell death by apoptosis; mature B-cell apoptosis; mature B-cell programmed cell death by apoptosis; mature B-lymphocyte apoptosis; mature B-lymphocyte programmed cell death by apoptosis; programmed cell death of mature B cells by apoptosis; programmed cell death of mature B lymphocytes by apoptosis; programmed cell death of mature B-cells by apoptosis; programmed cell death of mature B-lymphocytes by apoptosis; programmed cell death, mature B cells; programmed cell death, mature B lymphocytes; programmed cell death, mature B-cells; programmed cell death, mature B-lymphocytes
regulation of B cell apoptotic process (GO:0002902)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of B cell apoptotic process.
Synonyms: regulation of B cell apoptosis
negative regulation of B cell apoptotic process (GO:0002903)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.
Synonyms: down regulation of B cell apoptosis; down-regulation of B cell apoptosis; downregulation of B cell apoptosis; inhibition of B cell apoptosis; negative regulation of B cell apoptosis
positive regulation of B cell apoptotic process (GO:0002904)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.
Synonyms: activation of B cell apoptosis; positive regulation of B cell apoptosis; stimulation of B cell apoptosis; up regulation of B cell apoptosis; up-regulation of B cell apoptosis; upregulation of B cell apoptosis
regulation of mature B cell apoptotic process (GO:0002905)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.
Synonyms: regulation of mature B cell apoptosis
negative regulation of mature B cell apoptotic process (GO:0002906)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.
Synonyms: down regulation of mature B cell apoptosis; down-regulation of mature B cell apoptosis; downregulation of mature B cell apoptosis; inhibition of mature B cell apoptosis; negative regulation of mature B cell apoptosis
positive regulation of mature B cell apoptotic process (GO:0002907)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.
Synonyms: activation of mature B cell apoptosis; positive regulation of mature B cell apoptosis; stimulation of mature B cell apoptosis; up regulation of mature B cell apoptosis; up-regulation of mature B cell apoptosis; upregulation of mature B cell apoptosis
negative regulation of peripheral B cell deletion (GO:0002909)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.
Synonyms: down regulation of peripheral B cell deletion; down-regulation of peripheral B cell deletion; downregulation of peripheral B cell deletion; inhibition of peripheral B cell deletion
positive regulation of peripheral B cell deletion (GO:0002910)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.
Synonyms: activation of peripheral B cell deletion; stimulation of peripheral B cell deletion; up regulation of peripheral B cell deletion; up-regulation of peripheral B cell deletion; upregulation of peripheral B cell deletion
regulation of lymphocyte anergy (GO:0002911)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of lymphocyte anergy.
negative regulation of lymphocyte anergy (GO:0002912)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.
Synonyms: down regulation of lymphocyte anergy; down-regulation of lymphocyte anergy; downregulation of lymphocyte anergy; inhibition of lymphocyte anergy
positive regulation of lymphocyte anergy (GO:0002913)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.
Synonyms: activation of lymphocyte anergy; stimulation of lymphocyte anergy; up regulation of lymphocyte anergy; up-regulation of lymphocyte anergy; upregulation of lymphocyte anergy
regulation of central B cell anergy (GO:0002914)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of central B cell anergy.
negative regulation of central B cell anergy (GO:0002915)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.
Synonyms: down regulation of central B cell anergy; down-regulation of central B cell anergy; downregulation of central B cell anergy; inhibition of central B cell anergy
positive regulation of central B cell anergy (GO:0002916)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of central B cell anergy.
Synonyms: activation of central B cell anergy; stimulation of central B cell anergy; up regulation of central B cell anergy; up-regulation of central B cell anergy; upregulation of central B cell anergy
regulation of peripheral B cell anergy (GO:0002917)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.
negative regulation of peripheral B cell anergy (GO:0002918)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.
Synonyms: down regulation of peripheral B cell anergy; down-regulation of peripheral B cell anergy; downregulation of peripheral B cell anergy; inhibition of peripheral B cell anergy
regulation of humoral immune response (GO:0002920)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of a humoral immune response.
negative regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002924)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
Synonyms: down regulation of humoral immune response mediated by circulating immunoglobulin; down-regulation of humoral immune response mediated by circulating immunoglobulin; downregulation of humoral immune response mediated by circulating immunoglobulin; inhibition of humoral immune response mediated by circulating immunoglobulin
positive regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002925)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
Synonyms: activation of humoral immune response mediated by circulating immunoglobulin; stimulation of humoral immune response mediated by circulating immunoglobulin; up regulation of humoral immune response mediated by circulating immunoglobulin; up-regulation of humoral immune response mediated by circulating immunoglobulin; upregulation of humoral immune response mediated by circulating immunoglobulin
tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation (GO:0002926)
Namespace: biological_process
Definition: The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.
Synonyms: mcm5 modification; mcm5s2U34 biosynthesis; tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis
archaeosine-tRNA biosynthetic process (GO:0002927)
Namespace: biological_process
Definition: The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.
Comment: Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine.
MECO complex (GO:0002929)
Namespace: cellular_component
Definition: A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.
Synonyms: meta-coactivator complex
trabecular meshwork development (GO:0002930)
Namespace: biological_process
Definition: The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.
response to ischemia (GO:0002931)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
Comment: Ischemia always results in hypoxia; however, hypoxia can occur without ischemia.
tendon sheath development (GO:0002932)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.
lipid hydroxylation (GO:0002933)
Namespace: biological_process
Definition: The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
Synonyms: fatty acid hydroxylation
desmosome organization (GO:0002934)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
tRNA (adenine(37)-C2)-methyltransferase activity (GO:0002935)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosine37 in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine37 in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.
Synonyms: tRNA (adenine(37)-C(2))-methyltransferase activity; tRNA (adenosine(37)-C2-)-methyltransferase activity
bradykinin biosynthetic process (GO:0002936)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.
tRNA 4-thiouridine biosynthesis (GO:0002937)
Namespace: biological_process
Definition: The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.
Comment: In E. coli, two genes are involved, nuvA (aka Thi) and NuvC (aka iscS) . NuvA converts the trNA into an unidentified intermediate in an ATP dependent manner. NucC catalyzes the second step, transferring the sulfur from cysteine to an unidentified intermediate. NuvC also participates in thiamine synthesis.