LiteFold/GO huggingface dataset:
calcitonin binding (GO:0032841)
Namespace: molecular_function
Definition: Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.
obsolete hydroperoxide reductase activity (GO:0032843)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
Comment: This term was obsoleted because it represents a broad class of activities that are better represented by more specific terms that define the electron donor used in the reaction.
obsolete regulation of cellular pH reduction (GO:0032847)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.
Comment: This term was obsoleted because it represents 'regulation of regulation', which is redundant with direct pH regulation terms.
obsolete negative regulation of cellular pH reduction (GO:0032848)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.
Comment: This term was obsoleted because it represents 'regulation of regulation', which is redundant with direct pH regulation terms.
obsolete positive regulation of cellular pH reduction (GO:0032849)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
Comment: This term was obsoleted because it represents 'regulation of regulation', which is redundant with direct pH regulation terms.
ERMES complex (GO:0032865)
Namespace: cellular_component
Definition: A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
Synonyms: ER-mitochondria encounter structure; Mdm10/Mdm12/Mmm1 complex; mitochore; MMM1 complex
D-xylose reductase (NADPH) activity (GO:0032866)
Namespace: molecular_function
Definition: Catalysis of the reaction: xylitol + NADP+ = D-xylose + NADPH + H+.
Synonyms: D-xylose reductase activity; D-xylose:NADP reductase activity; xylose reductase activity
response to insulin (GO:0032868)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
Synonyms: response to insulin stimulus
cellular response to insulin stimulus (GO:0032869)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
cellular response to hormone stimulus (GO:0032870)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
regulation of karyogamy (GO:0032871)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.
regulation of stress-activated MAPK cascade (GO:0032872)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
Synonyms: regulation of p38 MAPK signaling; regulation of p38 MAPK signalling; regulation of stress-activated MAPK signaling pathway; regulation of stress-activated MAPK signalling pathway; regulation of stress-activated MAPKKK cascade; regulation of stress-activated MAPKKK signaling pathway; regulation of stress-activated MAPKKK signalling pathway
negative regulation of stress-activated MAPK cascade (GO:0032873)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
Synonyms: down regulation of stress-activated MAPK cascade; down-regulation of stress-activated MAPK cascade; downregulation of stress-activated MAPK cascade; inhibition of stress-activated MAPK cascade; negative regulation of p38 MAPK signaling; negative regulation of p38 MAPK signalling; negative regulation of stress-activated MAPK signaling pathway; negative regulation of stress-activated MAPK signalling pathway; negative regulation of stress-activated MAPKKK cascade; negative regulation of stress-activated MAPKKK signaling pathway; negative regulation of stress-activated MAPKKK signalling pathway
positive regulation of stress-activated MAPK cascade (GO:0032874)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
Synonyms: activation of stress-activated MAPK cascade; positive regulation of p38 MAPK signaling; positive regulation of p38 MAPK signalling; positive regulation of stress-activated MAPK signaling pathway; positive regulation of stress-activated MAPK signalling pathway; positive regulation of stress-activated MAPKKK cascade; positive regulation of stress-activated MAPKKK signaling pathway; positive regulation of stress-activated MAPKKK signalling pathway; stimulation of stress-activated MAPK cascade; up regulation of stress-activated MAPK cascade; up-regulation of stress-activated MAPK cascade; upregulation of stress-activated MAPK cascade
regulation of DNA endoreduplication (GO:0032875)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of DNA endoreduplication.
Synonyms: regulation of DNA endoreplication; regulation of DNA re-duplication
negative regulation of DNA endoreduplication (GO:0032876)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
Synonyms: down regulation of DNA endoreduplication; down-regulation of DNA endoreduplication; downregulation of DNA endoreduplication; inhibition of DNA endoreduplication; negative regulation of DNA endoreplication; negative regulation of DNA re-duplication
positive regulation of DNA endoreduplication (GO:0032877)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
Synonyms: activation of DNA endoreduplication; positive regulation of DNA endoreplication; positive regulation of DNA re-duplication; stimulation of DNA endoreduplication; up regulation of DNA endoreduplication; up-regulation of DNA endoreduplication; upregulation of DNA endoreduplication
regulation of establishment or maintenance of cell polarity (GO:0032878)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
regulation of localization (GO:0032879)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
Synonyms: regulation of localisation
regulation of protein localization (GO:0032880)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
Synonyms: regulation of cellular protein localisation; regulation of cellular protein localization; regulation of protein localisation
regulation of polysaccharide metabolic process (GO:0032881)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.
regulation of chitin metabolic process (GO:0032882)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.
Synonyms: regulation of chitin metabolism
regulation of chitin biosynthetic process (GO:0032883)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.
Synonyms: regulation of chitin anabolism; regulation of chitin biosynthesis; regulation of chitin formation; regulation of chitin synthesis
obsolete regulation of cell wall chitin biosynthetic process (GO:0032884)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.
Synonyms: regulation of cell wall chitin anabolism; regulation of cell wall chitin biosynthesis; regulation of cell wall chitin formation; regulation of cell wall chitin synthesis
Comment: The reason for obsoletion is that this term is mixing biological process and cellular component.
regulation of microtubule-based process (GO:0032886)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
regulation of spindle elongation (GO:0032887)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.
regulation of mitotic spindle elongation (GO:0032888)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
negative regulation of organic acid transport (GO:0032891)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: down regulation of organic acid transport; down-regulation of organic acid transport; downregulation of organic acid transport; inhibition of organic acid transport
positive regulation of organic acid transport (GO:0032892)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: activation of organic acid transport; stimulation of organic acid transport; up regulation of organic acid transport; up-regulation of organic acid transport; upregulation of organic acid transport
palmitoyl-CoA 9-desaturase activity (GO:0032896)
Namespace: molecular_function
Definition: Catalysis of the reaction: hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.
Synonyms: palmitoyl-CoA delta9-desaturase activity
negative regulation of viral transcription (GO:0032897)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
Synonyms: down regulation of viral transcription; down-regulation of viral transcription; downregulation of viral transcription; inhibition of viral transcription
neurotrophin production (GO:0032898)
Namespace: biological_process
Definition: The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
regulation of neurotrophin production (GO:0032899)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of a neurotrophin.
positive regulation of neurotrophin production (GO:0032901)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.
Synonyms: activation of neurotrophin production; stimulation of neurotrophin production; up regulation of neurotrophin production; up-regulation of neurotrophin production; upregulation of neurotrophin production
nerve growth factor production (GO:0032902)
Namespace: biological_process
Definition: The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.
Synonyms: beta-nerve growth factor production; NGF production
regulation of nerve growth factor production (GO:0032903)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).
Synonyms: regulation of beta-nerve growth factor production; regulation of NGF production
negative regulation of nerve growth factor production (GO:0032904)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).
Synonyms: down regulation of nerve growth factor production; down-regulation of nerve growth factor production; downregulation of nerve growth factor production; inhibition of nerve growth factor production; negative regulation of NGF production
transforming growth factor beta1 production (GO:0032905)
Namespace: biological_process
Definition: The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: TGF-B1 production; TGFB1 production; transforming growth factor-beta1 production
transforming growth factor beta2 production (GO:0032906)
Namespace: biological_process
Definition: The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: TGF-B2 production; TGFB2 production; transforming growth factor-beta2 production
transforming growth factor beta3 production (GO:0032907)
Namespace: biological_process
Definition: The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: TGF-B3 production; TGFB3 production; transforming growth factor-beta3 production
regulation of transforming growth factor beta1 production (GO:0032908)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.
Synonyms: regulation of TGF-B1 production; regulation of TGFB1 production; regulation of transforming growth factor-beta1 production
regulation of transforming growth factor beta2 production (GO:0032909)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
Synonyms: regulation of TGF-B2 production; regulation of TGFB2 production; regulation of transforming growth factor-beta2 production
regulation of transforming growth factor beta3 production (GO:0032910)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.
Synonyms: regulation of TGF-B3 production; regulation of TGFB3 production; regulation of transforming growth factor-beta3 production
negative regulation of transforming growth factor beta1 production (GO:0032911)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.
Synonyms: down regulation of transforming growth factor-beta1 production; down-regulation of transforming growth factor-beta1 production; downregulation of transforming growth factor-beta1 production; inhibition of transforming growth factor-beta1 production; negative regulation of TGF-B1 production; negative regulation of TGFB1 production; negative regulation of transforming growth factor-beta1 production
negative regulation of transforming growth factor beta3 production (GO:0032913)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.
Synonyms: down regulation of transforming growth factor-beta3 production; down-regulation of transforming growth factor-beta3 production; downregulation of transforming growth factor-beta3 production; inhibition of transforming growth factor-beta3 production; negative regulation of TGF-B3 production; negative regulation of TGFB3 production; negative regulation of transforming growth factor-beta3 production
positive regulation of transforming growth factor beta1 production (GO:0032914)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
Synonyms: activation of transforming growth factor-beta1 production; positive regulation of TGF-B1 production; positive regulation of TGFB1 production; stimulation of transforming growth factor-beta1 production; up regulation of transforming growth factor-beta1 production; up-regulation of transforming growth factor-beta1 production; upregulation of transforming growth factor-beta1 production
positive regulation of transforming growth factor beta2 production (GO:0032915)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.
Synonyms: activation of transforming growth factor-beta2 production; positive regulation of TGF-B2 production; positive regulation of TGFB2 production; positive regulation of transforming growth factor-beta2 production; stimulation of transforming growth factor-beta2 production; up regulation of transforming growth factor-beta2 production; up-regulation of transforming growth factor-beta2 production; upregulation of transforming growth factor-beta2 production
positive regulation of transforming growth factor beta3 production (GO:0032916)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.
Synonyms: activation of transforming growth factor-beta3 production; positive regulation of TGF-B3 production; positive regulation of TGFB3 production; positive regulation of transforming growth factor-beta3 production; stimulation of transforming growth factor-beta3 production; up regulation of transforming growth factor-beta3 production; up-regulation of transforming growth factor-beta3 production; upregulation of transforming growth factor-beta3 production
polyamine acetylation (GO:0032917)
Namespace: biological_process
Definition: The modification of polyamines by addition of acetyl groups.
spermidine acetylation (GO:0032918)
Namespace: biological_process
Definition: The modification of spermidine by addition of acetyl groups.
spermine acetylation (GO:0032919)
Namespace: biological_process
Definition: The modification of spermine by addition of acetyl groups.
putrescine acetylation (GO:0032920)
Namespace: biological_process
Definition: The modification of putrescine by addition of acetyl groups.
sarcosine oxidase complex (GO:0032921)
Namespace: cellular_component
Definition: A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.
circadian regulation of gene expression (GO:0032922)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
Synonyms: circadian regulation of protein expression; diurnal variation of gene expression; diurnal variation of protein expression
organic phosphonate biosynthetic process (GO:0032923)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
Synonyms: organophosphonate biosynthetic process
activin receptor signaling pathway (GO:0032924)
Namespace: biological_process
Definition: The series of molecular signals initiated by an extracellular ligand binding to an activin receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms: activin receptor signalling pathway
regulation of activin receptor signaling pathway (GO:0032925)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
Synonyms: regulation of activin receptor signalling pathway; regulation of activin signaling pathway; regulation of activin signalling pathway
negative regulation of activin receptor signaling pathway (GO:0032926)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
Synonyms: down regulation of activin receptor signaling pathway; down-regulation of activin receptor signaling pathway; downregulation of activin receptor signaling pathway; inhibition of activin receptor signaling pathway; negative regulation of activin receptor signalling pathway; negative regulation of activin signaling pathway; negative regulation of activin signalling pathway
positive regulation of activin receptor signaling pathway (GO:0032927)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
Synonyms: activation of activin receptor signaling pathway; positive regulation of activin receptor signalling pathway; positive regulation of activin signaling pathway; positive regulation of activin signalling pathway; stimulation of activin receptor signaling pathway; up regulation of activin receptor signaling pathway; up-regulation of activin receptor signaling pathway; upregulation of activin receptor signaling pathway
regulation of superoxide anion generation (GO:0032928)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.
Synonyms: regulation of superoxide release
negative regulation of superoxide anion generation (GO:0032929)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.
Synonyms: down regulation of superoxide release; down-regulation of superoxide release; downregulation of superoxide release; inhibition of superoxide release; negative regulation of superoxide release