LiteFold/GO huggingface dataset:
dipeptide transmembrane transport from lysosomal lumen to cytosol (GO:0141204)
Namespace: biological_process
Definition: The directed movement of dipeptide from the lysosomal lumen across the lysosomal membrane and into the cytosol.
Synonyms: dipeptide export from lysosomal lumen; dipeptide export from lysosome; transmembrane dipeptide transport from lysosomal lumen to cytosol
peptide lactyltransferase (ATP-dependent) activity (GO:0141207)
Namespace: molecular_function
Definition: Catalysis of the reaction: lactate + ATP + L-lysyl-[protein] = N(6)-lactoyl-L-lysyl-[protein]+ AMP + diphosphate. Can also act on free lactate.
Synonyms: peptide lactyltransferase (ATP dependent) activity; peptide lactyltransferase activity
NAD-dependent protein lysine delactylase activity (GO:0141208)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + N6-lactoyl-L-lysyl-[protein] + NAD = L-lysyl-[protein] + nicotinamide +2''-O-lactoyl-ADP-D-ribose, transfering a lactoyl group attached to a lysine residue in a protein to NAD.
Synonyms: protein lysine delactylase activity
oxysterol receptor signaling pathway (GO:0141209)
Namespace: biological_process
Definition: A nuclear receptor-mediated signaling pathway initiated by an oxysterol binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms: intracellular oxysterol receptor signaling pathway; nuclear receptor-mediated oxysterol signaling pathway
symbiont-mediated generation of symbiont replication vacuole (GO:0141213)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts vacuole organization in its host organism to form a protected environment in which it can replicate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
positive regulation of phospholipase C/protein kinase C signal transduction (GO:0141214)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of phospholipase C/protein kinase C signal transduction.
Synonyms: positive regulation of PLC/PKC signal transduction
N-acetyltaurine hydrolase activity (GO:0141215)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-acetyltaurine + H2O = acetate + taurine.
glycoRNA biosynthetic process (GO:0141217)
Namespace: biological_process
Definition: The posttranscriptional addition of a carbohydrate or carbohydrate derivative unit to residues in an RNA molecule. GlycoRNA consists of RNAs modified with secretory N-glycans that are presented on the cell surface.
Synonyms: glycoRNA biosynthesis; RNA glycosylation
histone deacetylase activity, hydrolytic mechanism (GO:0141221)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + N6-acetyl-L-lysyl-[histone] = acetate + L-lysyl-[histone].
Synonyms: histone deacetylase activity; histone deacetylase activity, NAD-independent
Comment: Histone deacytylase (HDAC) enzymes are divided into four classes: the Class I Rpd3-like proteins (in human: HDAC1, HDAC2, HDAC3, and HDAC8); the Class II Hda1-like proteins (in human: HDAC4, HDAC5, HDAC6, HDAC7, HDAC9, and HDAC10); the Class III Sir2-like proteins (in human: SIRT1, SIRT2, SIRT3, SIRT4, SIRT5, SIRT6, and SIRT7); and the Class IV protein (HDAC11 in human). Except for Class III enzymes, the mechanism is a metal-dependent hydrolysis of the acetylated substrate. The Class III HDACs use NAD+ as a reactant to deacetylate acetyl lysine residues of protein substrates forming nicotinamide, the deacetylated product, and the metabolite 2'-O-acetyl-ADP-ribose. Therefore, Class III are classified as transferases (EC:2) and others are hydrolases (EC:3).
cysteine synthase activity, acting on O-succinyl-L-serine (GO:0141223)
Namespace: molecular_function
Definition: Catalysis of the reaction: hydrogen sulfide + O-succinyl-L-serine = L-cysteine + succinate.
Synonyms: cysteine synthase activity
primary dendrite (GO:0150001)
Namespace: cellular_component
Definition: A dendrite emerging from the cell body (the soma) of a neuron.
distal dendrite (GO:0150002)
Namespace: cellular_component
Definition: The dendrite of the dendritic tree that is farthest away from the neuronal cell body (the soma).
regulation of spontaneous synaptic transmission (GO:0150003)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of spontaneous synaptic transmission.
dendritic spine origin (GO:0150004)
Namespace: cellular_component
Definition: The part of the dendritic spine neck where the spine arises from the dendritic shaft.
enzyme activator complex (GO:0150005)
Namespace: cellular_component
Definition: A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.
urease activator complex (GO:0150006)
Namespace: cellular_component
Definition: A protein complex required for the activation of urease. Activator subunits dissociate before urease has catalytic function.
bulk synaptic vesicle endocytosis (GO:0150008)
Namespace: biological_process
Definition: Endocytosis of large regions of presynaptic membrane after intense stimulation-mediated fusion of multiple synaptic vesicles. Bulk endocytosis is triggered by high loads of membrane addition through exocytosis of synaptic vesicles and elevated concentration of calcium in the presynapse.
Synonyms: activity-dependent bulk endocytosis; activity-dependent bulk synaptic vesicle endocytosis; ADBE; bulk endocytosis
regulation of neuron projection arborization (GO:0150011)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
Synonyms: regulation of neurite arborization; regulation of neurite branching; regulation of neuron projection branching
positive regulation of neuron projection arborization (GO:0150012)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
Synonyms: positive regulation of neurite arborization; positive regulation of neurite branching; positive regulation of neuron projection branching
negative regulation of neuron projection arborization (GO:0150013)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.
Synonyms: negative regulation of neurite arborization; negative regulation of neurite branching; negative regulation of neuron projection branching
apical distal dendrite (GO:0150014)
Namespace: cellular_component
Definition: Any dendrite in a dendritic tree that emerges near the apical pole of a neuron, and which is farthest away from the neuronal cell body (the soma).
basal distal dendrite (GO:0150016)
Namespace: cellular_component
Definition: Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is farthest away from the neuronal cell body (the soma).
basal proximal dendrite (GO:0150017)
Namespace: cellular_component
Definition: Any dendrite in a dendritic tree that emerges near the basal pole of a neuron (e.g. in bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon), and which is the closest to the cell body of the neuron (the soma).
basal dendrite development (GO:0150018)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.
basal dendrite morphogenesis (GO:0150019)
Namespace: biological_process
Definition: The process in which the anatomical structures of a basal dendrite are generated and organized.
basal dendrite arborization (GO:0150020)
Namespace: biological_process
Definition: The process in which the anatomical structures of a dendritic tree are generated on the basal neuron side and organized into dendritic branches.
apical dendrite morphogenesis (GO:0150021)
Namespace: biological_process
Definition: The process in which the anatomical structures of an apical dendrite are generated and organized.
apical dendrite development (GO:0150022)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an apical dendrite over time, from its formation to the mature structure.
apical dendrite arborization (GO:0150023)
Namespace: biological_process
Definition: The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.
oxidised low-density lipoprotein particle clearance (GO:0150024)
Namespace: biological_process
Definition: The process in which an oxidised low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms: ox-LDL particle clearance; oxidised LDL particle clearance; oxidized LDL particle clearance; oxidized low-density lipoprotein particle clearance; oxLDL particle clearance
oxidised low-density lipoprotein particle receptor activity (GO:0150025)
Namespace: molecular_function
Definition: Combining with an oxidised low-density lipoprotein particle and delivering the oxidised low-density lipoprotein particle into the cell via endocytosis.
Synonyms: ox-LDL particle receptor activity; ox-LDL receptor activity; oxidised LDL particle receptor activity; oxidised LDL receptor activity; oxidised low-density lipoprotein receptor activity; oxidized LDL particle receptor activity; oxidized LDL receptor activity; oxidized low-density lipoprotein particle receptor activity; oxidized low-density lipoprotein receptor activity; oxLDL particle receptor activity; oxLDL receptor activity
regulation of protein localization to lysosome (GO:0150031)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein localization to lysosome.
positive regulation of protein localization to lysosome (GO:0150032)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.
negative regulation of protein localization to lysosome (GO:0150033)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.
distal axon (GO:0150034)
Namespace: cellular_component
Definition: That part of an axon close to and including the growth cone or the axon terminus.
Synonyms: distal part of axon; distal part of the axon
regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission (GO:0150035)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of trans-synaptic signaling by BDNF, modulating synaptic transmission.
Comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission (GO:0150036)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission.
Comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
regulation of calcium-dependent activation of synaptic vesicle fusion (GO:0150037)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of calcium-dependent activation of synaptic vesicle fusion.
postsynaptic dense core vesicle exocytosis (GO:0150038)
Namespace: biological_process
Definition: The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a postsynaptic dense core vesicle by fusion of the granule with the plasma membrane of the postsynapse in response to increased cytosolic calcium levels.
structural constituent of synapse-associated extracellular matrix (GO:0150043)
Namespace: molecular_function
Definition: The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.
Synonyms: extra-synaptic extracellular matrix structural constituent; structural constituent of extra-synaptic extracellular matrix; synapse-associated extracellular matrix structural constituent
regulation of postsynaptic dense core vesicle exocytosis (GO:0150044)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of postsynaptic dense core vesicle exocytosis.
regulation of synaptic signaling by nitric oxide (GO:0150045)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of synaptic signaling by nitric oxide.
obsolete G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential (GO:0150047)
Namespace: molecular_function
Definition: OBSOLETE. G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.
Synonyms: G-protein coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential
Comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
cerebellar granule cell to Purkinje cell synapse (GO:0150048)
Namespace: cellular_component
Definition: A synapse of a granule cell fiber onto the dendrites of a Purkinje cell in cerebellum.
Synonyms: cerebellar parallel fiber to Purkinje cell synapse
postsynaptic Golgi apparatus (GO:0150051)
Namespace: cellular_component
Definition: The network of the Golgi apparatus structures located within the postsynapse.
Synonyms: Golgi outpost
regulation of postsynapse assembly (GO:0150052)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse.
cerebellar climbing fiber to Purkinje cell synapse (GO:0150053)
Namespace: cellular_component
Definition: A synapse of a climbing fiber onto the dendrites of a Purkinje cell in cerebellum. The climbing fiber originates from the inferior olivary nucleus of the medulla oblongata.
Synonyms: cerebellar climbing fibre to Purkinje cell synapse
regulation of postsynaptic neurotransmitter receptor diffusion trapping (GO:0150054)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of postsynaptic neurotransmitter receptor diffusion trapping.
amylin receptor complex 1 (GO:0150056)
Namespace: cellular_component
Definition: A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 1. Amylin receptor complex 1 (AMY1) also serves as a receptor for the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).
Synonyms: AMY1 complex
amylin receptor complex 2 (GO:0150057)
Namespace: cellular_component
Definition: A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 2. Amylin receptor complex 2 (AMY2) also serves as a receptor for adrenomedullin (AM/ADM).
Synonyms: AMY2 complex
amylin receptor complex 3 (GO:0150058)
Namespace: cellular_component
Definition: A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways.
Synonyms: AMY3 complex
amylin receptor 1 signaling pathway (GO:0150059)
Namespace: biological_process
Definition: The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).
Synonyms: AMY1 signaling pathway
amylin receptor 2 signaling pathway (GO:0150060)
Namespace: biological_process
Definition: The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 2 (AMY2), a G protein-coupled receptor complex, on the surface of the target cell. The AMY2 signaling pathway can also be initiated by adrenomedullin (AM/ADM).
Synonyms: AMY2 signaling pathway
amylin receptor 3 signaling pathway (GO:0150061)
Namespace: biological_process
Definition: The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 3 (AMY3), a G protein-coupled receptor complex, on the surface of the target cell. The AMY3 signaling pathway can also be initiated by the amyloid-beta complex. AMY3 signaling results in increased import of calcium ions into the cytosol across plasma membrane, increased phosphorylation of ERK1/2, Act, and a PKA regulatory subunit II, as well as increased expression of cFos.
Synonyms: AMY3 signaling pathway
complement-mediated synapse pruning (GO:0150062)
Namespace: biological_process
Definition: Synaptic pruning mediated by complement system signaling.
Synonyms: complement-dependent synapse pruning; synapse clearance; synapse disassembly; synapse elimination; synapse removal
visual system development (GO:0150063)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways.
Synonyms: optic pathway development; visual pathway development
regulation of deacetylase activity (GO:0150065)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of deacetylase activity.
obsolete negative regulation of deacetylase activity (GO:0150066)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of tubulin deacetylase activity (GO:0150067)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of tubulin deacetylase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of tubulin deacetylase activity (GO:0150068)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of tubulin deacetylase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of tubulin deacetylase activity (GO:0150069)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of arginase activity (GO:0150070)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of arginase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of arginase activity (GO:0150071)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of arginase activity.
Comment: This term was obsoleted because it represents a molecular function.
positive regulation of protein-glutamine gamma-glutamyltransferase activity (GO:0150074)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.
obsolete negative regulation of protein-glutamine gamma-glutamyltransferase activity (GO:0150075)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of protein-glutamine gamma-glutamyltransferase activity.
Comment: This term was obsoleted because it represents a molecular function.
neuroinflammatory response (GO:0150076)
Namespace: biological_process
Definition: The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents.
Synonyms: nerve tissue inflammatory response; nervous tissue inflammatory response; neural tissue inflammatory response
regulation of neuroinflammatory response (GO:0150077)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of neuroinflammatory response.
positive regulation of neuroinflammatory response (GO:0150078)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.
negative regulation of neuroinflammatory response (GO:0150079)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.
multiple synapse bouton (GO:0150086)
Namespace: cellular_component
Definition: A single axon terminal bouton making contact onto two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.
Synonyms: MSB; multi-synapse; multi-synapse bouton; multi-synaptic bouton; multiple spine synapse bouton; multiple synapse; multiple-synapse bouton; multisynapse; multisynapse bouton; multisynaptic bouton
multiple synapse bouton, contacting single dendrite (GO:0150087)
Namespace: cellular_component
Definition: A single axon terminal bouton making contact onto two or more dendritic spines protruding from the same dendrite.
Synonyms: MSB1; type 1 multi-synapse bouton; type 1 multi-synaptic bouton; type 1 multiple spine synapse bouton; type 1 multiple-synapse bouton; type 1 multisynapse bouton; type 1 multisynaptic bouton
multiple synapse bouton, contacting multiple dendrites (GO:0150088)
Namespace: cellular_component
Definition: A single axon terminal bouton making contact onto two or more dendritic spines protruding from multiple dendrites.
Synonyms: MSB2; type 2 multi-synapse bouton; type 2 multi-synaptic bouton; type 2 multiple spine synapse bouton; type 2 multiple-synapse bouton; type 2 multisynapse bouton; type 2 multisynaptic bouton
multiple spine synapse organization (GO:0150089)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.
Synonyms: multi-synapse organisation; multi-synapse organization; multi-synaptic organisation; multi-synaptic organization; multiple spine synapse organisation; multisynapse organisation; multisynapse organization; multisynaptic organisation; multisynaptic organization
multiple spine synapse organization, single dendrite (GO:0150090)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and a single dendrite.