LiteFold/GO huggingface dataset:
protein-RNA complex assembly (GO:0022618)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
Synonyms: ribonucleoprotein complex assembly; RNA-protein complex assembly; RNP complex assembly
generative cell differentiation (GO:0022619)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.
microgametophyte vegetative cell differentiation (GO:0022620)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a microgametophyte. The microgametophyte vegetative cell gives rise to the pollen tube.
Synonyms: tube cell differentiation; vegetative cell differentiation
root system development (GO:0022622)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.
proteasome-activating nucleotidase complex (GO:0022623)
Namespace: cellular_component
Definition: A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.
Synonyms: PAN
proteasome accessory complex (GO:0022624)
Namespace: cellular_component
Definition: A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.
cytosolic large ribosomal subunit (GO:0022625)
Namespace: cellular_component
Definition: The large subunit of a ribosome located in the cytosol.
Synonyms: 50S ribosomal subunit; 60S ribosomal subunit; eukaryotic ribosomal LSU; prokaryotic large ribosomal subunit
cytosolic ribosome (GO:0022626)
Namespace: cellular_component
Definition: A ribosome located in the cytosol.
Synonyms: 70S ribosome; 80S ribosome
cytosolic small ribosomal subunit (GO:0022627)
Namespace: cellular_component
Definition: The small subunit of a ribosome located in the cytosol.
Synonyms: 30S ribosomal subunit; 40S ribosomal subunit; eukaryotic ribosomal SSU; prokaryotic small ribosomal subunit
chloroplast small ribosomal subunit (GO:0022629)
Namespace: cellular_component
Definition: The small subunit of a ribosome contained within a chloroplast.
Synonyms: chloroplast ribosomal small subunit complex; chloroplast ribosomal SSU complex
passive transmembrane transporter activity (GO:0022803)
Namespace: molecular_function
Definition: Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.
Synonyms: facilitated diffusion; porters; uniporter activity z
active transmembrane transporter activity (GO:0022804)
Namespace: molecular_function
Definition: Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
Synonyms: active carrier activity; carrier activity; permease activity; pump activity
membrane potential driven uniporter activity (GO:0022810)
Namespace: molecular_function
Definition: Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
Synonyms: porter
sodium ion uniporter activity (GO:0022818)
Namespace: molecular_function
Definition: Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
potassium ion uniporter activity (GO:0022819)
Namespace: molecular_function
Definition: Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
solute:potassium antiporter activity (GO:0022821)
Namespace: molecular_function
Definition: Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
Synonyms: potassium ion antiporter activity
transmitter-gated monoatomic ion channel activity (GO:0022824)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
Synonyms: ionotropic neurotransmitter receptor activity; transmitter-gated ion channel activity
obsolete copper-exporting ATPase activity (GO:0022825)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: copper-exporting ATPase activity
Comment: This term was made obsolete because it was a placeholder during work on transporter terms, and was not defined.
obsolete phosphorylation-gated channel activity (GO:0022828)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
wide pore channel activity (GO:0022829)
Namespace: molecular_function
Definition: Enables the energy-independent facilitated diffusion of propanediol through a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
Synonyms: gap junction activity; non-gated, wide pore channel activity
narrow pore, gated channel activity (GO:0022831)
Namespace: molecular_function
Definition: Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.
Synonyms: ion channels
voltage-gated channel activity (GO:0022832)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
ligand-gated channel activity (GO:0022834)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
transmitter-gated channel activity (GO:0022835)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
Synonyms: extracellular substance gated channel activity; neurotransmitter-gated channel activity
gated channel activity (GO:0022836)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
monoatomic ion-gated channel activity (GO:0022839)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
Synonyms: ion gated channel activity; monoatomic ion gated channel activity
leak channel activity (GO:0022840)
Namespace: molecular_function
Definition: Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
potassium ion leak channel activity (GO:0022841)
Namespace: molecular_function
Definition: Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
narrow pore channel activity (GO:0022842)
Namespace: molecular_function
Definition: Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.
voltage-gated monoatomic cation channel activity (GO:0022843)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms: voltage-gated cation channel activity
acetylcholine-gated monoatomic cation-selective channel activity (GO:0022848)
Namespace: molecular_function
Definition: Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
Synonyms: acetylcholine-activated cation-selective channel activity; acetylcholine-gated cation channel activity; acetylcholine-gated cation-selective channel activity; ionotropic acetylcholine receptor activity; nAChR; nicotinergic acetylcholine receptor activity; nicotinic acetylcholine-activated cation-selective channel activity
serotonin-gated monoatomic cation channel activity (GO:0022850)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.
Synonyms: 5-hydroxytryptamine-gated receptor-channel; serotonin-activated cation-selective channel activity; serotonin-gated cation channel activity; serotonin-gated cation-selective channel activity; serotonin-gated monoatomic cation-selective channel activity
Comment: Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'G protein-coupled serotonin receptor activity ; GO:0004993'.
GABA-gated chloride ion channel activity (GO:0022851)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.
glycine-gated chloride ion channel activity (GO:0022852)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
active monoatomic ion transmembrane transporter activity (GO:0022853)
Namespace: molecular_function
Definition: Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
Synonyms: active ion transmembrane transporter activity
obsolete active large uncharged polar molecule transmembrane transporter activity (GO:0022854)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a large uncharged polar molecule from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
Synonyms: active large uncharged polar molecule transmembrane transporter activity
Comment: This term was made obsolete because 'large uncharged polar molecule' is not a useful chemical grouping term.
protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity (GO:0022855)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: glucose PTS transporter activity
protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity (GO:0022856)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: sorbitol PTS transporter activity
transmembrane transporter activity (GO:0022857)
Namespace: molecular_function
Definition: Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
Synonyms: substrate-specific transmembrane transporter activity; substrate-specific transporter activity; uptake permease activity; uptake transmembrane transporter activity
alanine transmembrane transporter activity (GO:0022858)
Namespace: molecular_function
Definition: Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.
obsolete dephosphorylation-gated channel activity (GO:0022859)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
obsolete transmembrane electron transfer carrier (GO:0022865)
Namespace: molecular_function
Definition: OBSOLETE. Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics.
Comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process.
obsolete transmembrane 1-electron transfer carrier (GO:0022866)
Namespace: molecular_function
Definition: OBSOLETE. Enables transfer of one electron across a membrane.
Synonyms: transmembrane one-electron transfer carrier
Comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process.
obsolete transmembrane 2-electron transfer carrier (GO:0022867)
Namespace: molecular_function
Definition: OBSOLETE. Enables transfer of two electrons across a membrane.
Synonyms: transmembrane two-electron transfer carrier
Comment: The reason for obsoletion is that the term does not represent a molecular function but rather a process.
protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity (GO:0022869)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: lactose PTS transporter activity
protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity (GO:0022870)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane according to the reaction: D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: mannose PTS transporter activity
protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity (GO:0022871)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: sorbose PTS transporter activity
protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity (GO:0022872)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: mannitol PTS transporter activity
protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity (GO:0022873)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: maltose PTS transporter activity
protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity (GO:0022874)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane according to the reaction: D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho-beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]. This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: cellobiose PTS transporter activity
protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity (GO:0022875)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: galactitol PTS transporter activity
protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity (GO:0022876)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: galactosamine PTS transporter activity
protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity (GO:0022877)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: fructose PTS transporter activity
protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity (GO:0022878)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: sucrose PTS transporter activity
protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity (GO:0022879)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: trehalose PTS transporter activity
protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity (GO:0022880)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane by the reaction: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: N-acetylglucosamine PTS transporter activity
protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity (GO:0022881)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: N-acetylgalactosamine PTS transporter activity
protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity (GO:0022882)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
Synonyms: beta-glucoside PTS transporter activity
zinc efflux transmembrane transporter activity (GO:0022883)
Namespace: molecular_function
Definition: Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.
Synonyms: zinc efflux permease activity
macromolecule transmembrane transporter activity (GO:0022884)
Namespace: molecular_function
Definition: Enables the transfer of a macromolecule from one side of a membrane to the other.
bacteriocin transmembrane transporter activity (GO:0022885)
Namespace: molecular_function
Definition: Enables the transfer of a bacteriocin from one side of a membrane to the other.
channel-forming ionophore activity (GO:0022886)
Namespace: molecular_function
Definition: Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.
Synonyms: ionophore activity
obsolete serine transmembrane transporter activity (GO:0022889)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.
Comment: This term was obsoleted because is is redundant with L-serine transmembrane transporter activity ; GO:0015194.