LiteFold/GO huggingface dataset:
serotonin receptor activity (GO:0099589)
Namespace: molecular_function
Definition: Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
neurotransmitter receptor internalization (GO:0099590)
Namespace: biological_process
Definition: A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.
endocytosed synaptic vesicle processing via endosome (GO:0099592)
Namespace: biological_process
Definition: The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
Synonyms: synaptic vesicle processing via endosome involved in synaptic vesicle recycling
endocytosed synaptic vesicle to endosome fusion (GO:0099593)
Namespace: biological_process
Definition: Fusion of an endocytosed synaptic vesicle with an endosome.
regulation of neurotransmitter receptor activity (GO:0099601)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors.
neurotransmitter receptor regulator activity (GO:0099602)
Namespace: molecular_function
Definition: A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
ligand-gated calcium channel activity (GO:0099604)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
regulation of action potential firing rate (GO:0099605)
Namespace: biological_process
Definition: Any process that regulates the frequency of action potentials in a spike train.
microtubule plus-end directed mitotic chromosome migration (GO:0099606)
Namespace: biological_process
Definition: The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.
Synonyms: plus-end directed chromosome gliding
lateral attachment of mitotic spindle microtubules to kinetochore (GO:0099607)
Namespace: biological_process
Definition: The cellular process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).
regulation of action potential firing pattern (GO:0099608)
Namespace: biological_process
Definition: Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.
Synonyms: spike train sculpting
microtubule lateral binding (GO:0099609)
Namespace: molecular_function
Definition: Binding to the side of a microtubule.
action potential initiation (GO:0099610)
Namespace: biological_process
Definition: The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.
Synonyms: action potential firing; action potential triggering
regulation of action potential firing threshold (GO:0099611)
Namespace: biological_process
Definition: Any process that regulates the potential at which an axon potential is triggered.
protein localization to axon (GO:0099612)
Namespace: biological_process
Definition: A process in which a protein is transported to or maintained in a location within an axon.
protein localization to cell wall (GO:0099613)
Namespace: biological_process
Definition: The process of directing proteins towards the cell-wall.
extrinsic component of matrix side of mitochondrial inner membrane (GO:0099616)
Namespace: cellular_component
Definition: The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
matrix side of mitochondrial inner membrane (GO:0099617)
Namespace: cellular_component
Definition: The leaflet of a mitochondrial inner membrane that faces the matrix, including any protein embedded in, attached to, or peripherally associated with it.
UDP-glucuronate dehydrogenase activity (GO:0099618)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-alpha-D-glucuronate + NAD+ = UDP-beta-L-threo-pentopyranos-4-ulose + CO2 + NADH.
Synonyms: UDP-GlcUA decarboxylase activity; UDP-glucuronic acid dehydrogenase activity
UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity (GO:0099619)
Namespace: molecular_function
Definition: Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
Synonyms: 10-formyltetrahydrofolate:UDP-4-amino-4-deoxy-beta-L-arabinose N-formyltransferase activity; ArnAFT activity; UDP-L-Ara4N formyltransferase activity
UDP-4-amino-4-deoxy-L-arabinose:2-oxoglutarate transaminase activity (GO:0099620)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinose + 2-oxoglutarate = UDP-beta-L-threo-pentopyranos-4-ulose + L-glutamate.
Synonyms: UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase; UDP-4-amino-4-deoxy-beta-L-arabinose:2-oxoglutarate aminotransferase; UDP-4-amino-4-deoxy-L-arabinose aminotransferase; UDP-4-amino-4-deoxy-L-arabinose---oxoglutarate aminotransferase; UDP-Ara4O aminotransferase; UDP-L-Ara4N transaminase
undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (GO:0099621)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.
Synonyms: Ara4FN transferase activity; undecaprenyl phosphate-L-Ara4FN transferase activity; undecaprenyl-phosphate Ara4FN transferase activity
cardiac muscle cell membrane repolarization (GO:0099622)
Namespace: biological_process
Definition: The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
regulation of cardiac muscle cell membrane repolarization (GO:0099623)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.
Synonyms: heart repolarization; regulation of cardiac muscle cell repolarization; regulation of cardiomyocyte membrane repolarization
atrial cardiac muscle cell membrane repolarization (GO:0099624)
Namespace: biological_process
Definition: The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
ventricular cardiac muscle cell membrane repolarization (GO:0099625)
Namespace: biological_process
Definition: The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels (GO:0099626)
Namespace: molecular_function
Definition: Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.
Synonyms: voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
neurotransmitter receptor cycle (GO:0099627)
Namespace: biological_process
Definition: The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).
neurotransmitter receptor diffusion trapping (GO:0099628)
Namespace: biological_process
Definition: The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.
postsynaptic specialization of symmetric synapse (GO:0099629)
Namespace: cellular_component
Definition: A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.
Synonyms: postsynaptic density of inhibitory synapse
postsynaptic neurotransmitter receptor cycle (GO:0099630)
Namespace: biological_process
Definition: The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
postsynaptic endocytic zone cytoplasmic component (GO:0099631)
Namespace: cellular_component
Definition: The cytoplasmic component of the postsynaptic endocytic zone.
protein transport within plasma membrane (GO:0099632)
Namespace: biological_process
Definition: A process in which protein is transported from one region of the plasma membrane to another.
protein localization to postsynaptic specialization membrane (GO:0099633)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).
Synonyms: protein localisation in postsynaptic specialization membrane
postsynaptic specialization membrane (GO:0099634)
Namespace: cellular_component
Definition: The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels (GO:0099635)
Namespace: molecular_function
Definition: Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.
cytoplasmic streaming (GO:0099636)
Namespace: biological_process
Definition: The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.
neurotransmitter receptor transport (GO:0099637)
Namespace: biological_process
Definition: The directed movement of neurotransmitter receptors.
endosome to plasma membrane protein transport (GO:0099638)
Namespace: biological_process
Definition: The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
neurotransmitter receptor transport, endosome to plasma membrane (GO:0099639)
Namespace: biological_process
Definition: The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.
axo-dendritic protein transport (GO:0099640)
Namespace: biological_process
Definition: The directed movement of proteins along microtubules in neuron projections.
Synonyms: axonal protein transport
anterograde axonal protein transport (GO:0099641)
Namespace: biological_process
Definition: The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.
Synonyms: anterograde axon cargo transport
retrograde axonal protein transport (GO:0099642)
Namespace: biological_process
Definition: The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.
Synonyms: retrograde axon cargo transport
signal release from synapse (GO:0099643)
Namespace: biological_process
Definition: Any signal release from a synapse.
protein localization to presynaptic membrane (GO:0099644)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.
Synonyms: protein localisation in presynaptic membrane; protein localisation to presynaptic membrane; protein localization in presynaptic membrane
neurotransmitter receptor localization to postsynaptic specialization membrane (GO:0099645)
Namespace: biological_process
Definition: A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
Synonyms: neurotransmitter receptor localisation in postsynaptic specialization membrane
neurotransmitter receptor transport, plasma membrane to endosome (GO:0099646)
Namespace: biological_process
Definition: Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.
obsolete integral component of synaptic membrane (GO:0099699)
Namespace: cellular_component
Definition: OBSOLETE. The component of the synaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration (GO:0099703)
Namespace: biological_process
Definition: The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.
cell cortex region (GO:0099738)
Namespace: cellular_component
Definition: The complete extent of cell cortex that underlies some some region of the plasma membrane.
Synonyms: perimembrane region
regulation of skeletal muscle contraction by action potential (GO:0100001)
Namespace: biological_process
Definition: Any action potential process that regulates skeletal muscle contraction.
obsolete negative regulation of protein kinase activity by protein phosphorylation (GO:0100002)
Namespace: biological_process
Definition: OBSOLETE. Any protein phosphorylation process that negatively regulates protein kinase activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of sodium ion transport by transcription from RNA polymerase II promoter (GO:0100003)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sodium ion transport.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter (GO:0100005)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates ethanol catabolic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of sulfite transport by transcription from RNA polymerase II promoter (GO:0100006)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates sulfite transport.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter (GO:0100007)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates ceramide biosynthetic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
regulation of fever generation by prostaglandin biosynthetic process (GO:0100008)
Namespace: biological_process
Definition: Any prostaglandin biosynthetic process process that regulates fever generation.
regulation of fever generation by prostaglandin secretion (GO:0100009)
Namespace: biological_process
Definition: Any prostaglandin secretion process that regulates fever generation.
positive regulation of fever generation by prostaglandin biosynthetic process (GO:0100010)
Namespace: biological_process
Definition: Any prostaglandin biosynthetic process process that positively_regulates fever generation.
positive regulation of fever generation by prostaglandin secretion (GO:0100011)
Namespace: biological_process
Definition: Any prostaglandin secretion process that positively_regulates fever generation.
obsolete regulation of heart induction by canonical Wnt signaling pathway (GO:0100012)
Namespace: biological_process
Definition: OBSOLETE. Any canonical Wnt signaling pathway process that regulates heart induction.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter (GO:0100013)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates fatty acid beta-oxidation.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of mating type switching by transcription from RNA polymerase II promoter (GO:0100014)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates mating type switching.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter (GO:0100015)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates inositol biosynthetic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter (GO:0100016)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter (GO:0100017)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates single organismal cell-cell adhesion.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of glucose import by transcription from RNA polymerase II promoter (GO:0100018)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates glucose import.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter (GO:0100019)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling.
Comment: The reason for obsoletion is that cAMP-mediated signaling is not mediated by transcription from RNA polII promoter.
obsolete regulation of transport by transcription from RNA polymerase II promoter (GO:0100020)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates transport.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of iron ion transport by transcription from RNA polymerase II promoter (GO:0100021)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates iron ion transport.
Synonyms: regulation of iron ion import by transcription from RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of meiotic nuclear division by transcription from RNA polymerase II promoter (GO:0100023)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter (GO:0100024)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter (GO:0100025)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that negatively regulates cellular amino acid biosynthetic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of DNA repair by transcription from RNA polymerase II promoter (GO:0100026)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates DNA repair.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter (GO:0100027)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis.
obsolete regulation of histone modification by transcription from RNA polymerase II promoter (GO:0100029)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone modification.
Comment: This term was obsoleted because it describes a process that does not exist.
obsolete regulation of histone acetylation by transcription from RNA polymerase II promoter (GO:0100030)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone acetylation.
Comment: This term was obsoleted because it describes a process that does not exist.
obsolete regulation of histone methylation by transcription from RNA polymerase II promoter (GO:0100031)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates histone methylation.
Comment: This term was obsoleted because it describes a process that does not exist.