LiteFold/GO huggingface dataset:
peptide antibiotic biosynthetic process (GO:0030651)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.
Synonyms: peptide antibiotic anabolism; peptide antibiotic biosynthesis; peptide antibiotic formation; peptide antibiotic synthesis
peptide antibiotic catabolic process (GO:0030652)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.
Synonyms: peptide antibiotic breakdown; peptide antibiotic catabolism; peptide antibiotic degradation
obsolete beta-lactam antibiotic metabolic process (GO:0030653)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
Synonyms: beta-lactam antibiotic metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
beta-lactam antibiotic biosynthetic process (GO:0030654)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
Synonyms: beta-lactam antibiotic anabolism; beta-lactam antibiotic biosynthesis; beta-lactam antibiotic formation; beta-lactam antibiotic synthesis
beta-lactam antibiotic catabolic process (GO:0030655)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
Synonyms: beta-lactam antibiotic breakdown; beta-lactam antibiotic catabolism; beta-lactam antibiotic degradation
regulation of vitamin metabolic process (GO:0030656)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
Synonyms: regulation of vitamin metabolism
obsolete regulation of coenzyme and prosthetic group metabolic process (GO:0030657)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzymes and prosthetic groups.
Synonyms: regulation of coenzyme and prosthetic group metabolic process
Comment: This term was made obsolete because it was replaced by more specific terms.
transport vesicle membrane (GO:0030658)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a transport vesicle.
Synonyms: constitutive secretory pathway transport vesicle membrane; secretory vesicle membrane
Golgi-associated vesicle membrane (GO:0030660)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
Synonyms: Golgi vesicle membrane
chitosome membrane (GO:0030661)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a chitosome.
coated vesicle membrane (GO:0030662)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a coated vesicle.
COPI-coated vesicle membrane (GO:0030663)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a COPI-coated vesicle.
Synonyms: COPI coated vesicle membrane
clathrin-coated vesicle membrane (GO:0030665)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a clathrin-coated vesicle.
Synonyms: clathrin coated vesicle membrane
secretory granule membrane (GO:0030667)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a secretory granule.
Synonyms: secretory vesicle membrane
apicomplexan dense granule membrane (GO:0030668)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.
clathrin-coated endocytic vesicle membrane (GO:0030669)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a clathrin-coated endocytic vesicle.
phagocytic vesicle membrane (GO:0030670)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a phagocytic vesicle.
Synonyms: phagosome membrane
clathrin-coated phagocytic vesicle membrane (GO:0030671)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.
synaptic vesicle membrane (GO:0030672)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a synaptic vesicle.
axolemma (GO:0030673)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
Synonyms: axonal membrane
protein-macromolecule adaptor activity (GO:0030674)
Namespace: molecular_function
Definition: An adaptor activity that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
Synonyms: protein binding, bridging; protein complex scaffold activity; protein recruiting activity; protein-containing complex scaffold activity; protein-protein adaptor
ribonuclease P complex (GO:0030677)
Namespace: cellular_component
Definition: A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.
Synonyms: RNase P complex
Comment: Note that chloroplasts possess a complex that is called 'RNase P' because it catalyzes pre-tRNA cleavage, but the chloroplast complex appears not to contain RNA.
mitochondrial ribonuclease P complex (GO:0030678)
Namespace: cellular_component
Definition: A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species. The complex contains a single RNA molecule and a single protein molecule in yeast (PMID:12045094), but comprises three proteins and lacks an RNA component in humans.
Synonyms: mitochondrial RNase P complex
cyanelle ribonuclease P complex (GO:0030679)
Namespace: cellular_component
Definition: A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
Synonyms: cyanelle RNase P complex
multimeric ribonuclease P complex (GO:0030681)
Namespace: cellular_component
Definition: A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
Synonyms: multimeric RNase P complex
symbiont-mediated perturbation of host defenses (GO:0030682)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts the normal execution of a host organism's defense response. The host defense response is mounted by the host in response to the presence of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: avoidance of defenses of other organism during symbiotic interaction; avoidance of defenses of other organism involved in symbiotic interaction; avoidance of host defences; avoidance of host defenses; evasion of host defence response; evasion of other organism defence response; evasion or tolerance of defense response of other organism during symbiotic interaction; evasion or tolerance of defense response of other organism involved in symbiotic interaction; evasion or tolerance of defenses of other organism; evasion or tolerance of defenses of other organism during symbiotic interaction; evasion or tolerance of defenses of other organism involved in symbiotic interaction; evasion or tolerance of host defense response; evasion or tolerance of host defenses; mitigation of host defenses by symbiont; perturbation of host defenses by symbiont
obsolete nucleolar preribosome (GO:0030685)
Namespace: cellular_component
Definition: OBSOLETE. Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.
Comment: The reason for obsoletion is that this term was added in error (combines a component and a localization)
90S preribosome (GO:0030686)
Namespace: cellular_component
Definition: A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
preribosome, small subunit precursor (GO:0030688)
Namespace: cellular_component
Definition: A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
Synonyms: 43S preribosome
Comment: Note that this complex is 43S in Saccharomyces.
Noc complex (GO:0030689)
Namespace: cellular_component
Definition: Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.
Comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the definition uses Saccharomyces gene product names because this complex has only been described in Saccharomyces cerevisiae and no other names have yet arisen; the term nevertheless can be used for analogous complexes in other eukaryotes, and the definition can be changed if better wording is found.
Noc1p-Noc2p complex (GO:0030690)
Namespace: cellular_component
Definition: A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.
Comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.
Noc2p-Noc3p complex (GO:0030691)
Namespace: cellular_component
Definition: A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.
Comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.
Noc4p-Nop14p complex (GO:0030692)
Namespace: cellular_component
Definition: A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.
Synonyms: Nop7 complex; Nop7 subcomplex
Comment: Noc complexes exhibit a dynamic intranuclear location; consider also annotating to 'nucleolus ; GO:0005730' and/or 'nucleoplasm ; GO:0005654' and/or 'nuclear pore ; GO:0005643'. Note that the term name uses Saccharomyces gene product names because no other names have yet arisen for this complex; the term nevertheless can be used for analogous complexes in other eukaryotes, and the name can be changed if better wording is found.
bacterial-type flagellum basal body, rod (GO:0030694)
Namespace: cellular_component
Definition: The central portion of the bacterial-type flagellar basal body, which spans the periplasm and threads through the rings.
Synonyms: flagellar basal body, rod; flagellin-based flagellum basal body, rod
GTPase regulator activity (GO:0030695)
Namespace: molecular_function
Definition: Binds to and modulates the activity of a GTPase.
Synonyms: small GTPase regulator activity; small GTPase regulatory/interacting protein activity
obsolete tRNA (m5U54) methyltransferase activity (GO:0030696)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.
Synonyms: RUMT
Comment: This term was obsoleted because it is an unnecessary grouing class.
tRNA (uracil(54)-C5)-methyltransferase activity, S-adenosyl methionine-dependent (GO:0030697)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + uridine54 in tRNA = 5-methyluridine54 in tRNA + H+ + S-adenosyl-L-homocysteine.
Synonyms: M5U-methyltransferase activity; ribothymidyl synthase activity; RUMT; RUMT activity; S-adenosyl methionine-dependent tRNA (m5U54) methyltransferase activity; S-adenosyl-L-methionine:tRNA (uracil-5-)-methyltransferase activity; S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity; transfer RNA uracil 5-methyltransferase activity; transfer RNA uracil methylase activity; tRNA (uracil(54)-C(5))-methyltransferase activity, S-adenosyl methionine-dependent; tRNA (uracil-5-)-methyltransferase activity; tRNA uracil 5-methyltransferase activity; tRNA:m(5)U54-methyltransferase activity; tRNA:m5U54-methyltransferase activity
obsolete 5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity (GO:0030698)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.
Synonyms: RUMT
Comment: This term was obsoleted because it represents the same activity as tRNA (uracil(54)-C(5))-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent ; GO:0047151.
glycine reductase complex (GO:0030700)
Namespace: cellular_component
Definition: Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.
Comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'glycine reductase activity ; GO:0030699'.
NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity (GO:0030701)
Namespace: molecular_function
Definition: Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].
Synonyms: ADP-ribosyltransferase activity; NAD+:[dinitrogen reductase] (ADP-D-ribosyl)transferase activity; NAD--azoferredoxin (ADP-ribose)transferase activity; NAD-azoferredoxin (ADPribose)transferase activity; NAD-dinitrogen-reductase ADP-D-ribosyltransferase activity
eggshell formation (GO:0030703)
Namespace: biological_process
Definition: Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.
vitelline membrane formation (GO:0030704)
Namespace: biological_process
Definition: Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.
cytoskeleton-dependent intracellular transport (GO:0030705)
Namespace: biological_process
Definition: The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
germarium-derived oocyte differentiation (GO:0030706)
Namespace: biological_process
Definition: The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.
Synonyms: oocyte cell differentiation
follicle cell of egg chamber development (GO:0030707)
Namespace: biological_process
Definition: The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
germarium-derived female germ-line cyst encapsulation (GO:0030708)
Namespace: biological_process
Definition: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.
border follicle cell delamination (GO:0030709)
Namespace: biological_process
Definition: The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.
Synonyms: border cell delamination
regulation of border follicle cell delamination (GO:0030710)
Namespace: biological_process
Definition: Any process that regulates the frequency, rate or extent of border cell delamination.
Synonyms: regulation of border cell delamination
positive regulation of border follicle cell delamination (GO:0030711)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of border cell delamination.
Synonyms: activation of border follicle cell delamination; positive regulation of border cell delamination; stimulation of border follicle cell delamination; up regulation of border follicle cell delamination; up-regulation of border follicle cell delamination; upregulation of border follicle cell delamination
negative regulation of border follicle cell delamination (GO:0030712)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of border cell delamination.
Synonyms: down regulation of border follicle cell delamination; down-regulation of border follicle cell delamination; downregulation of border follicle cell delamination; inhibition of border follicle cell delamination; negative regulation of border cell delamination
follicle cell of egg chamber stalk formation (GO:0030713)
Namespace: biological_process
Definition: Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.
oocyte growth in germarium-derived egg chamber (GO:0030715)
Namespace: biological_process
Definition: The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.
oocyte fate determination (GO:0030716)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Synonyms: oocyte cell fate determination
oocyte karyosome formation (GO:0030717)
Namespace: biological_process
Definition: The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
germ-line stem cell population maintenance (GO:0030718)
Namespace: biological_process
Definition: Any process by which an organism or tissue maintains a population of germ-line stem cells.
P granule organization (GO:0030719)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
Synonyms: P granule organization and biogenesis; polar granule organisation; polar granule organization and biogenesis
oocyte localization involved in germarium-derived egg chamber formation (GO:0030720)
Namespace: biological_process
Definition: Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.
Synonyms: establishment and maintenance of oocyte localization in egg chamber; establishment and maintenance of oocyte position during oogenesis; oocyte localisation involved in germarium-derived egg chamber formation; oocyte localization during germarium-derived egg chamber formation; oocyte localization during oogenesis; oocyte positioning during oogenesis; oogenesis, establishment and maintenance of oocyte localization; oogenesis, oocyte localization
testicular fusome organization (GO:0030724)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.
Synonyms: testicular fusome organisation; testicular fusome organization and biogenesis
germline ring canal formation (GO:0030725)
Namespace: biological_process
Definition: Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.
Synonyms: ring canal formation
male germline ring canal formation (GO:0030726)
Namespace: biological_process
Definition: Formation of the intercellular bridges that connect the germ-line cells of a male cyst.
Synonyms: spermatocyte ring canal formation; testicular ring canal formation
germarium-derived female germ-line cyst formation (GO:0030727)
Namespace: biological_process
Definition: Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.
Synonyms: germarium-derived female germline cyst formation
ovulation (GO:0030728)
Namespace: biological_process
Definition: The release of a mature ovum/oocyte from an ovary.
acetoacetate-CoA ligase activity (GO:0030729)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.
Synonyms: acetoacetate:CoA ligase (AMP-forming); acetoacetyl-CoA synthetase activity
triglyceride storage (GO:0030730)
Namespace: biological_process
Definition: The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
Synonyms: retention of triacylglycerol; retention of triglyceride; sequestering of triacylglycerol; sequestering of triglyceride; sequestration of triacylglycerol; sequestration of triglyceride; storage of triacylglycerol; storage of triglyceride; triacylglycerol retention; triacylglycerol sequestering; triacylglycerol sequestration; triacylglycerol storage; triglyceride retention; triglyceride sequestering; triglyceride sequestration