LiteFold/GO huggingface dataset:
obsolete outer membrane exporter porin (GO:0015479)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: outer membrane exporter porin
Comment: This term was made obsolete because it contains both component and function information.
obsolete secretin (sensu Bacteria) (GO:0015480)
Namespace: molecular_function
Definition: OBSOLETE. Secretins are Gram-negative bacterial outer membrane proteins that form multimeric pores through which macromolecules, usually proteins, can pass. Form homomultimeric ring structures, 10-20 subunits per complex, with large central pores (inner diameters of 5-10 nm).
Synonyms: secretin (sensu Bacteria)
Comment: This term was made obsolete because it represents a class of gene products.
maltose transporting porin activity (GO:0015481)
Namespace: molecular_function
Definition: Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
Synonyms: maltoporin
obsolete voltage-gated anion channel porin activity (GO:0015482)
Namespace: molecular_function
Definition: OBSOLETE. This term was not defined before being made obsolete.
Synonyms: voltage-dependent anion channel porin activity; voltage-gated anion channel porin activity
Comment: This term was made obsolete because it wrongly combines voltage-gated anion channel activity and porin activity.
long-chain fatty acid transporting porin activity (GO:0015483)
Namespace: molecular_function
Definition: Enables the transfer of a long-chain fatty acid from one side of a membrane to the other. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
obsolete hemolysin activity (GO:0015484)
Namespace: molecular_function
Definition: OBSOLETE. Any substance that causes the lysis of red blood cells.
Synonyms: hemolysin activity
Comment: This term was made obsolete because it represents a gene product.
cholesterol binding (GO:0015485)
Namespace: molecular_function
Definition: Binding to cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
glycoside-pentoside-hexuronide:cation symporter activity (GO:0015486)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.
melibiose:monoatomic cation symporter activity (GO:0015487)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).
Synonyms: melibiose permease activity; melibiose:cation symporter activity; melibiose:monovalent cation symporter activity
glucuronide:cation symporter activity (GO:0015488)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).
Synonyms: glucuronide:monovalent cation symporter activity; glucuronoside permease activity
putrescine transmembrane transporter activity (GO:0015489)
Namespace: molecular_function
Definition: Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
obsolete cation:cation antiporter activity (GO:0015491)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).
Comment: This term was obsoleted because it was too general for a grouping class.
phenylalanine:proton symporter activity (GO:0015492)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).
Synonyms: phenylalanine:hydrogen symporter activity
lysine:proton symporter activity (GO:0015493)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).
Synonyms: lysine:hydrogen symporter activity
aromatic amino acid:proton symporter activity (GO:0015494)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).
Synonyms: aromatic amino acid:hydrogen symporter activity
gamma-aminobutyric acid:proton symporter activity (GO:0015495)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).
Synonyms: 4-aminobutanoate:hydrogen symporter activity; 4-aminobutanoate:proton symporter activity; 4-aminobutyrate:hydrogen symporter activity; 4-aminobutyrate:proton symporter activity; GABA:hydrogen symporter activity; GABA:proton symporter activity; gamma-aminobutyric acid permease activity; gamma-aminobutyric acid:hydrogen symporter activity
Comment: See also the molecular function term 'neurotransmitter transporter activity ; GO:0005326'.
putrescine:ornithine antiporter activity (GO:0015496)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).
Synonyms: putrescine-ornithine antiporter activity; putrescine/ornithine antiporter activity; putrescine:hydrogen symporter activity
pantothenate:sodium symporter activity (GO:0015498)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).
formate transmembrane transporter activity (GO:0015499)
Namespace: molecular_function
Definition: Enables the transfer of formate from one side of a membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
Synonyms: formate uptake permease activity; formate uptake transmembrane transporter activity
obsolete threonine/serine:sodium symporter activity (GO:0015500)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (threonine or serine)(out) + Na+(out) = (threonine or serine)(in) + Na+(in).
Synonyms: threonine/serine:sodium symporter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
glutamate:sodium symporter activity (GO:0015501)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).
Synonyms: sodium/excitatory glutamate cotransporter activity; sodium/excitatory glutamate symporter activity
glutathione-regulated potassium exporter activity (GO:0015503)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
cytosine:proton symporter activity (GO:0015504)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).
Synonyms: cytosine permease activity; cytosine:hydrogen ion symporter activity
uracil:monoatomic cation symporter activity (GO:0015505)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).
Synonyms: uracil permease activity; uracil:cation symporter activity
nucleoside:proton symporter activity (GO:0015506)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).
Synonyms: nucleoside permease activity; nucleoside:hydrogen ion symporter activity; nucleoside:hydrogen symporter activity
high-affinity secondary active nitrite transmembrane transporter activity (GO:0015513)
Namespace: molecular_function
Definition: Catalysis of the transfer of nitrite from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. In high affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
Synonyms: nitrite uptake permease activity
nitrite efflux transmembrane transporter activity (GO:0015514)
Namespace: molecular_function
Definition: Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.
Synonyms: nitrite extrusion permease activity
citrate:succinate antiporter activity (GO:0015515)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
tartrate:succinate antiporter activity (GO:0015516)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).
galactose:proton symporter activity (GO:0015517)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).
Synonyms: galactose:hydrogen symporter activity; lactose, galactose:hydrogen symporter activity
arabinose:proton symporter activity (GO:0015518)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).
Synonyms: arabinose efflux permease activity; arabinose efflux transmembrane transporter activity; arabinose:hydrogen symporter activity
D-xylose:proton symporter activity (GO:0015519)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).
Synonyms: D-xylose:hydrogen symporter activity
tetracycline:proton antiporter activity (GO:0015520)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).
Synonyms: tetracyclin:hydrogen antiporter activity; tetracyclin:proton antiporter activity; tetracycline:hydrogen antiporter activity
obsolete bicyclomycin/sulfathiazole:hydrogen antiporter activity (GO:0015521)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (bicyclomycin or sulfathiazole)(in) + H+(out) = (bicyclomycin or sulfathiazole)(out) + H+(in).
Synonyms: bicyclomycin/sulfathiazole:hydrogen antiporter activity; bicyclomycin/sulfathiazole:proton antiporter activity; bicyclomycin/sulphathiazole:hydrogen antiporter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
obsolete hydrophobic uncoupler:proton antiporter activity (GO:0015522)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.
Synonyms: hydrophobic uncoupler:hydrogen antiporter activity
Comment: The reason for obsoletion is that this term represented a specific protein in TCDB, 2.A.1.2.9, which actually is a sugar transporter that seems to also function as a multidrug efflux protein.
obsolete L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity (GO:0015524)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: H+(out) + (L-arabinose or beta-D-thiogalactopyranoside)(in) = H+(in) + (L-arabinose or beta-D-thiogalactopyranoside)(out).
Synonyms: L-arabinose/beta-D-thiogalactopyranoside:hydrogen antiporter activity; L-arabinose/beta-D-thiogalactopyranoside:proton antiporter activity
Comment: This term was made obsolete because it represents a gene product rather than a single discrete molecular function.
obsolete carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity (GO:0015525)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity; carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:proton antiporter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
hexose-phosphate:phosphate antiporter activity (GO:0015526)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + phosphate(in) = hexose phosphate(in) +  phosphate(out).
Synonyms: hexose-phosphate:inorganic phosphate antiporter activity
lactose:proton symporter activity (GO:0015528)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).
Synonyms: lactose, galactose:hydrogen symporter activity; lactose:hydrogen symporter activity
raffinose:proton symporter activity (GO:0015529)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).
Synonyms: raffinose:hydrogen symporter activity
shikimate transmembrane transporter activity (GO:0015530)
Namespace: molecular_function
Definition: Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.
citrate:proton symporter activity (GO:0015531)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).
Synonyms: citrate:hydrogen symporter activity
alpha-ketoglutarate:proton symporter activity (GO:0015532)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).
Synonyms: 2-oxoglutarate:hydrogen symporter activity; 2-oxoglutarate:proton symporter activity; alpha-ketoglutarate:hydrogen symporter activity
shikimate:proton symporter activity (GO:0015533)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).
Synonyms: shikimate:hydrogen symporter activity
obsolete proline/glycine/betaine:hydrogen/sodium symporter activity (GO:0015534)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (proline, glycine or betaine)(out) + (H+ or Na+)(out) = (proline, glycine or betaine)(in) + (H+ or Na+)(in).
Synonyms: proline/glycine/betaine:hydrogen/sodium symporter activity; proline/glycine/betaine:proton/sodium symporter
Comment: This term was made obsolete because it represents a multifunctional gene product.
fucose:proton symporter activity (GO:0015535)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).
Synonyms: fucose:hydrogen symporter activity
sialic acid:proton symporter activity (GO:0015538)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).
Synonyms: sialic acid permease activity; sialic acid:hydrogen symporter activity
hexuronate:monoatomic cation symporter activity (GO:0015539)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.
Synonyms: hexuronate (glucuronate/galacturonate) porter activity; hexuronate porter activity; hexuronate:cation symporter activity
3-hydroxyphenyl propionate:proton symporter activity (GO:0015540)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).
Synonyms: 3-hydroxyphenyl propionate porter activity; 3-hydroxyphenyl propionate:hydrogen ion symporter activity
secondary active cyanate transmembrane transporter activity (GO:0015541)
Namespace: molecular_function
Definition: Enables the transfer of cyanate from one side of a membrane to the other.
Synonyms: cyanate porter activity
obsolete lactose/glucose efflux transporter activity (GO:0015543)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: glucose or lactose(in) = glucose or lactose(out).
Synonyms: lactose/glucose efflux transporter activity
Comment: This term was made obsolete because it represents two molecular functions.
phenyl propionate uniporter activity (GO:0015544)
Namespace: molecular_function
Definition: Enables the transfer of phenyl propionate from one side of a membrane to the other.
Synonyms: phenyl propionate permease activity
bicyclomycin transmembrane transporter activity (GO:0015545)
Namespace: molecular_function
Definition: Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
Synonyms: bicyclomycin transporter activity; bicyclomycin/sulfathiazole:hydrogen antiporter activity
sulfathiazole transmembrane transporter activity (GO:0015546)
Namespace: molecular_function
Definition: Enables the transfer of sulfathiazole from one side of a membrane to the other. Sulfathiazole is an antibacterial agent of the sulfonamide group.
Synonyms: bicyclomycin/sulfathiazole:hydrogen antiporter activity; sulphathiazole transporter activity
obsolete nalidixic acid transmembrane transporter activity (GO:0015547)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of nalidixic acid from one side of a membrane to the other. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.
Synonyms: carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity; nalidixic acid transporter activity
Comment: The reason for obsoletion is that these terms are beyond the scope of GO.
obsolete organomercurial transmembrane transporter activity (GO:0015548)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of organomercurial compounds from one side of a membrane to the other. Organomercurial substances are any organic compound containing a mercury atom.
Synonyms: carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity; organomercurial transporter activity
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete carbonyl cyanide m-chlorophenylhydrazone transmembrane transporter activity (GO:0015549)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of carbonyl cyanide m-chlorophenylhydrazone from one side of a membrane to the other. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
Synonyms: carbonyl cyanide m-chlorophenylhydrazone transporter activity; carbonyl cyanide m-chlorophenylhydrazone/nalidixic acid/organomercurials:hydrogen antiporter activity; CCCP transporter activity
Comment: The reason for obsoletion is that these terms are beyond the scope of GO.
3-hydroxyphenyl propanoate transmembrane transporter activity (GO:0015551)
Namespace: molecular_function
Definition: Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.
Synonyms: 3-hydroxyphenyl propionate transmembrane transporter activity
propionate transmembrane transporter activity (GO:0015552)
Namespace: molecular_function
Definition: Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.
xanthosine transmembrane transporter activity (GO:0015553)
Namespace: molecular_function
Definition: Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.
tartrate transmembrane transporter activity (GO:0015554)
Namespace: molecular_function
Definition: Enables the transfer of tartrate from one side of a membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.
C4-dicarboxylate transmembrane transporter activity (GO:0015556)
Namespace: molecular_function
Definition: Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.