LiteFold/GO huggingface dataset:
tRNA guanine ribose methylation (GO:0002938)
Namespace: biological_process
Definition: The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.
tRNA N1-guanine methylation (GO:0002939)
Namespace: biological_process
Definition: The process whereby a guanine in tRNA is methylated at position N1 of the guanine.
Synonyms: tRNA m1-guanine biosynthesis
tRNA N2-guanine methylation (GO:0002940)
Namespace: biological_process
Definition: The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.
Synonyms: tRNA m2-guanine biosynthesis
tRNA m2,2-guanine biosynthesis (GO:0002942)
Namespace: biological_process
Definition: The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.
tRNA dihydrouridine synthesis (GO:0002943)
Namespace: biological_process
Definition: The process whereby a uridine in a transfer RNA is converted to dihydrouridine.
Comment: Dihydrouridine is found in numerous positions within loop I, the so-called dihydrouridine loop, of many transfer RNAs. Most often found at positions 16 and 17, but also sometimes at positions 20, 20a, and 20b.
cyclin K-CDK12 complex (GO:0002944)
Namespace: cellular_component
Definition: A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
Synonyms: CycK/Cdk12 complex
cyclin K-CDK13 complex (GO:0002945)
Namespace: cellular_component
Definition: A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
Synonyms: CycK/Cdk13 complex
tRNA C5-cytosine methylation (GO:0002946)
Namespace: biological_process
Definition: The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.
Synonyms: tRNA 5-methylcytosine biosynthesis
tumor necrosis factor receptor superfamily complex (GO:0002947)
Namespace: cellular_component
Definition: A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.
Synonyms: TNF receptor superfamily complex
archaeosine synthase activity (GO:0002948)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.
Synonyms: ArcS; glutamine:preQ0-tRNA amidinotransferase
ceramide phosphoethanolamine synthase activity (GO:0002950)
Namespace: molecular_function
Definition: Catalysis of the reaction: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H+.
leukotriene-C(4) hydrolase activity (GO:0002951)
Namespace: molecular_function
Definition: Catalysis of the reaction leukotriene C(4) + H2O= leukotriene D(4) + L-glutamate.
Comment: The mouse enzyme is specific for leukotriene C(4), while the human enzyme also has considerable activity toward glutathione and oxidized glutathione (cf. EC:3.4.19.13). PMID:9774450 cites that the mouse form of this enzyme failed to measure activity towards glutathione.
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity (GO:0002952)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2S)-2-hydroxy-3,4-dioxopentyl phosphate = 3-hydroxy-2,4-dioxopentyl phosphate.
Synonyms: phospho-AI-2 isomerase activity
5'-deoxynucleotidase activity (GO:0002953)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate.
obsolete generation of a signal involved in cell-cell signaling (GO:0003001)
Namespace: biological_process
Definition: OBSOLETE. The cellular process that creates a physical entity or change in state, i.e. a signal, that originates in one cell and is used to transfer information to another cell. This process begins with the initial formation of the signal and ends with the mature form and placement of the signal.
Synonyms: formation of a signal; generation of a signal involved in cell-cell signaling; generation of a signal involved in cell-cell signalling; signal generation
Comment: This term was made obsolete because biosynthesis of a signal occurs before the start of cell-cell signaling.
regionalization (GO:0003002)
Namespace: biological_process
Definition: The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
Synonyms: pattern formation
obsolete follicular fluid formation in ovarian follicle antrum involved in fused antrum stage (GO:0003003)
Namespace: biological_process
Definition: OBSOLETE. The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.
Synonyms: follicular fluid formation in ovarian follicle antrum during fused antrum stage
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage (GO:0003004)
Namespace: biological_process
Definition: OBSOLETE. The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.
Synonyms: follicular fluid formation in ovarian follicle antrum during distinct antral spaces stage
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage (GO:0003005)
Namespace: biological_process
Definition: OBSOLETE. The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.
Synonyms: follicular fluid formation in ovarian follicle antrum during scattered antral spaces stage
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
heart morphogenesis (GO:0003007)
Namespace: biological_process
Definition: The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
Synonyms: cardiac morphogenesis
system process (GO:0003008)
Namespace: biological_process
Definition: A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
Synonyms: organ system process
skeletal muscle contraction (GO:0003009)
Namespace: biological_process
Definition: A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.
voluntary skeletal muscle contraction (GO:0003010)
Namespace: biological_process
Definition: A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.
involuntary skeletal muscle contraction (GO:0003011)
Namespace: biological_process
Definition: A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.
muscle system process (GO:0003012)
Namespace: biological_process
Definition: An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
Synonyms: muscle physiological process
circulatory system process (GO:0003013)
Namespace: biological_process
Definition: An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.
renal system process (GO:0003014)
Namespace: biological_process
Definition: An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
Synonyms: excretory system process; kidney system process
heart process (GO:0003015)
Namespace: biological_process
Definition: A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
Synonyms: cardiac process
respiratory system process (GO:0003016)
Namespace: biological_process
Definition: A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
Synonyms: respiratory gaseous exchange
vascular process in circulatory system (GO:0003018)
Namespace: biological_process
Definition: A circulatory process that occurs at the level of the vasculature.
Synonyms: vasculature process
detection of reduced oxygen by chemoreceptor signaling (GO:0003020)
Namespace: biological_process
Definition: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
Synonyms: detection of reduced oxygen by chemoreceptor signalling
detection of increased carbon dioxide by chemoreceptor signaling (GO:0003021)
Namespace: biological_process
Definition: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
Synonyms: detection of increased carbon dioxide by chemoreceptor signalling
baroreceptor detection of increased arterial stretch (GO:0003023)
Namespace: biological_process
Definition: The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.
baroreceptor detection of decreased arterial stretch (GO:0003024)
Namespace: biological_process
Definition: The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.
regulation of systemic arterial blood pressure by baroreceptor feedback (GO:0003025)
Namespace: biological_process
Definition: The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.
Synonyms: baroreceptor regulation of systemic arterial blood pressure
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback (GO:0003026)
Namespace: biological_process
Definition: The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.
Synonyms: aortic arch baroreceptor control of systemic arterial blood pressure
regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling (GO:0003027)
Namespace: biological_process
Definition: The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
Synonyms: carotid body chemoreceptor regulation of systemic arterial blood pressure; carotid body chemoreceptor response to lowering of systemic arterial blood pressure; regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling; vagal reflex
regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling (GO:0003028)
Namespace: biological_process
Definition: The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
Synonyms: aortic body chemoreceptor regulation of systemic arterial blood pressure; aortic body chemoreceptor response to lowering of systemic arterial blood pressure; regulation of systemic arterial blood pressure by aortic body chemoreceptor signalling
detection of hypoxic conditions in blood by carotid body chemoreceptor signaling (GO:0003029)
Namespace: biological_process
Definition: The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.
Synonyms: detection of hypoxic conditions in blood by carotid body chemoreceptor signalling
detection of hydrogen ion (GO:0003030)
Namespace: biological_process
Definition: The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.
detection of carbon dioxide (GO:0003031)
Namespace: biological_process
Definition: The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.
detection of oxygen (GO:0003032)
Namespace: biological_process
Definition: The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.
detection of hypoxic conditions in blood by aortic body chemoreceptor signaling (GO:0003033)
Namespace: biological_process
Definition: The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.
Synonyms: detection of hypoxic conditions in blood by aortic body chemoreceptor signalling
detection of increased carbon dioxide by aortic body chemoreceptor signaling (GO:0003034)
Namespace: biological_process
Definition: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.
Synonyms: detection of increased carbon dioxide by aortic body chemoreceptor signalling
detection of increased carbon dioxide by carotid body chemoreceptor signaling (GO:0003035)
Namespace: biological_process
Definition: The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.
Synonyms: detection of increased carbon dioxide by carotid body chemoreceptor signalling
detection of pH by aortic body chemoreceptor signaling (GO:0003036)
Namespace: biological_process
Definition: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.
Synonyms: detection of pH by aortic body chemoreceptor signalling
detection of pH by carotid body chemoreceptor signaling (GO:0003037)
Namespace: biological_process
Definition: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.
Synonyms: detection of pH by carotid body chemoreceptor signalling
detection of reduced oxygen by aortic body chemoreceptor signaling (GO:0003038)
Namespace: biological_process
Definition: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.
Synonyms: detection of reduced oxygen by aortic body chemoreceptor signalling
detection of reduced oxygen by carotid body chemoreceptor signaling (GO:0003039)
Namespace: biological_process
Definition: The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.
Synonyms: detection of reduced oxygen by carotid body chemoreceptor signalling
excitation of vasomotor center by aortic body chemoreceptor signaling (GO:0003040)
Namespace: biological_process
Definition: The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
Synonyms: excitation of vasomotor center by aortic body chemoreceptor signalling
excitation of vasomotor center by carotid body chemoreceptor signaling (GO:0003041)
Namespace: biological_process
Definition: The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
Synonyms: excitation of vasomotor center by carotid body chemoreceptor signalling
obsolete vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure (GO:0003043)
Namespace: biological_process
Definition: OBSOLETE. A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
Synonyms: vasoconstriction of artery during aortic body chemoreceptor response to lowering of systemic arterial blood pressure
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
Synonyms: blood pressure regulation mediated by a chemical signal
regulation of systemic arterial blood pressure by physical factors (GO:0003045)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by detection of forces within the circulatory system.
Synonyms: blood pressure regulation by physical factors
regulation of systemic arterial blood pressure by stress relaxation (GO:0003046)
Namespace: biological_process
Definition: The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.
Synonyms: blood pressure regulation by stress relaxation
regulation of systemic arterial blood pressure by norepinephrine (GO:0003048)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.
Synonyms: blood pressure regulation by norepinephrine; regulation of blood pressure by noradrenaline
regulation of systemic arterial blood pressure by capillary fluid shift (GO:0003049)
Namespace: biological_process
Definition: The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.
Synonyms: blood pressure regulation by capillary fluid shift
regulation of systemic arterial blood pressure by atrial natriuretic peptide (GO:0003050)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.
Synonyms: blood pressure regulation by ANP; blood pressure regulation by atrial natriuretic peptide
angiotensin-mediated drinking behavior (GO:0003051)
Namespace: biological_process
Definition: The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.
Synonyms: angiotensin mediated drinking behavior
circadian regulation of systemic arterial blood pressure (GO:0003052)
Namespace: biological_process
Definition: Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.
circadian regulation of heart rate (GO:0003053)
Namespace: biological_process
Definition: Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.
Synonyms: circadian regulation of heart contraction rate
circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus (GO:0003054)
Namespace: biological_process
Definition: The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.
Synonyms: master pacemaker clock regulation of blood pressure; SCN regulation of blood pressure
circadian regulation of heart rate by the suprachiasmatic nucleus (GO:0003055)
Namespace: biological_process
Definition: The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.
Synonyms: circadian regulation of heart contraction rate by the suprachiasmatic nucleus; master pacemaker clock regulation of heart rate; SCN regulation of heart rate
regulation of vascular associated smooth muscle contraction (GO:0003056)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.
Synonyms: regulation of vascular smooth muscle contraction
regulation of the force of heart contraction by chemical signal (GO:0003057)
Namespace: biological_process
Definition: The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
Synonyms: chemical cardiac inotropy; regulation of the force of heart muscle contraction by chemical signal
hormonal regulation of the force of heart contraction (GO:0003058)
Namespace: biological_process
Definition: The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
Synonyms: hormonal cardiac inotropy; hormonal regulation of the force of heart muscle contraction
positive regulation of the force of heart contraction by epinephrine (GO:0003059)
Namespace: biological_process
Definition: The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.
Synonyms: adrenaline cardiac inotropy; adrenaline regulation of the strength of heart muscle contraction; epinephrine cardiac inotropy; increased force of heart contraction by epinephrine; positive regulation of heart contraction by adrenaline; positive regulation of heart contraction by epinephrine