LiteFold/GO huggingface dataset:
trachea development (GO:0060438)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.
trachea morphogenesis (GO:0060439)
Namespace: biological_process
Definition: The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
trachea formation (GO:0060440)
Namespace: biological_process
Definition: The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.
epithelial tube branching involved in lung morphogenesis (GO:0060441)
Namespace: biological_process
Definition: The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
Synonyms: lung branching morphogenesis
branching involved in prostate gland morphogenesis (GO:0060442)
Namespace: biological_process
Definition: The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.
Synonyms: prostate branching; prostate gland branching morphogenesis
mammary gland morphogenesis (GO:0060443)
Namespace: biological_process
Definition: The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
branching involved in mammary gland duct morphogenesis (GO:0060444)
Namespace: biological_process
Definition: The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
Synonyms: mammary gland branching morphogenesis
branching involved in salivary gland morphogenesis (GO:0060445)
Namespace: biological_process
Definition: The process in which the branching structure of the salivary gland is generated and organized.
branching involved in open tracheal system development (GO:0060446)
Namespace: biological_process
Definition: The process in which the anatomical structures of branches in the open tracheal system are generated and organized.
bud outgrowth involved in lung branching (GO:0060447)
Namespace: biological_process
Definition: The process in which a region of the lung epithelium initiates an outgrowth.
Synonyms: bud formation involved in lung branching
dichotomous subdivision of terminal units involved in lung branching (GO:0060448)
Namespace: biological_process
Definition: The process in which a lung bud bifurcates.
Synonyms: bud bifurcation involved in lung branching
bud elongation involved in lung branching (GO:0060449)
Namespace: biological_process
Definition: The process in which a bud in the lung grows out from the point where it is formed.
positive regulation of hindgut contraction (GO:0060450)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
negative regulation of hindgut contraction (GO:0060451)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
positive regulation of cardiac muscle contraction (GO:0060452)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of cardiac muscle contraction.
regulation of gastric acid secretion (GO:0060453)
Namespace: biological_process
Definition: Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
positive regulation of gastric acid secretion (GO:0060454)
Namespace: biological_process
Definition: Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
negative regulation of gastric acid secretion (GO:0060455)
Namespace: biological_process
Definition: Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
positive regulation of digestive system process (GO:0060456)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
negative regulation of digestive system process (GO:0060457)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
right lung development (GO:0060458)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.
Synonyms: right pulmonary development
left lung development (GO:0060459)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.
Synonyms: left pulmonary development
left lung morphogenesis (GO:0060460)
Namespace: biological_process
Definition: The process in which anatomical structures of the left lung are generated and organized.
right lung morphogenesis (GO:0060461)
Namespace: biological_process
Definition: The process in which anatomical structures of the right lung are generated and organized.
lung lobe morphogenesis (GO:0060463)
Namespace: biological_process
Definition: The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.
lung lobe formation (GO:0060464)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.
pharynx development (GO:0060465)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
Synonyms: pharyngeal development
activation of meiosis involved in egg activation (GO:0060466)
Namespace: biological_process
Definition: Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.
Synonyms: reactivation of meiosis after fertilization; resumption of meiosis involved in egg activation
negative regulation of fertilization (GO:0060467)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
prevention of polyspermy (GO:0060468)
Namespace: biological_process
Definition: The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.
Synonyms: negative regulation of fertilization involved in egg activation; polyspermy block
obsolete positive regulation of transcription involved in egg activation (GO:0060469)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation.
Synonyms: activation of the egg genome; activation of the maternal genome
Comment: This term was obsoleted because it represents GO-CAM model.
positive regulation of cytosolic calcium ion concentration involved in egg activation (GO:0060470)
Namespace: biological_process
Definition: The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.
Synonyms: elevation of cytosolic calcium ion concentration involved in egg activation
cortical granule exocytosis (GO:0060471)
Namespace: biological_process
Definition: The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms: cortical granule release; cortical reaction
positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration (GO:0060472)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.
Synonyms: positive regulation of cortical granule exocytosis by elevation of cytosolic calcium ion concentration
cortical granule (GO:0060473)
Namespace: cellular_component
Definition: A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
Synonyms: cortical vesicle
positive regulation of flagellated sperm motility involved in capacitation (GO:0060474)
Namespace: biological_process
Definition: The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
Synonyms: positive regulation of sperm motility involved in capacitation
obsolete positive regulation of actin filament polymerization involved in acrosome reaction (GO:0060475)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.
Synonyms: positive regulation of actin polymerization involved in acrosome reaction
Comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
protein localization involved in acrosome reaction (GO:0060476)
Namespace: biological_process
Definition: The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.
Synonyms: protein localisation involved in acrosome reaction
obsolete peptidyl-serine phosphorylation involved in acrosome reaction (GO:0060477)
Namespace: biological_process
Definition: OBSOLETE. The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction.
Comment: The reason for obsoletion is that this term does not represent a specific process.
acrosomal vesicle exocytosis (GO:0060478)
Namespace: biological_process
Definition: The calcium ion regulated exocytosis which results in fusion of the acrosomal vesicle with the plasma membrane of the sperm as part of the acrosome reaction.
Synonyms: acrosomal granule exocytosis; acrosome exocytosis
lung cell differentiation (GO:0060479)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms: pulmonary cell differentiation
lung goblet cell differentiation (GO:0060480)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.
Synonyms: pulmonary goblet cell differentiation
lobar bronchus epithelium development (GO:0060481)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.
lobar bronchus development (GO:0060482)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.
lobar bronchus mesenchyme development (GO:0060483)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.
lung-associated mesenchyme development (GO:0060484)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.
Synonyms: lung mesenchyme development; pulmonary mesenchyme development
mesenchyme development (GO:0060485)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.
Synonyms: mesenchymal development
club cell differentiation (GO:0060486)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
Synonyms: Clara cell differentiation
lung epithelial cell differentiation (GO:0060487)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.
Synonyms: pulmonary epithelial cell differentiation
orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis (GO:0060488)
Namespace: biological_process
Definition: The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.
Synonyms: perpendicular dichotomous subdivision of terminal units involved in lung branching morphogenesis
lateral sprouting involved in lung morphogenesis (GO:0060490)
Namespace: biological_process
Definition: The process in which a branch forms along the side of the lung epithelial tube.
regulation of cell projection assembly (GO:0060491)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of cell projection assembly.
Synonyms: regulation of cell projection formation
lung induction (GO:0060492)
Namespace: biological_process
Definition: The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.
obsolete mesenchymal-endodermal cell signaling involved in lung induction (GO:0060493)
Namespace: biological_process
Definition: OBSOLETE. Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.
Synonyms: mesenchymal-endodermal cell signalling involved in lung induction
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
inductive mesenchymal-endodermal cell signaling (GO:0060494)
Namespace: biological_process
Definition: Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.
Synonyms: inductive mesenchymal-endodermal cell signalling
obsolete cell-cell signaling involved in lung development (GO:0060495)
Namespace: biological_process
Definition: OBSOLETE. Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.
Synonyms: cell-cell signalling involved in lung development
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mesenchymal-epithelial cell signaling involved in lung development (GO:0060496)
Namespace: biological_process
Definition: Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.
Synonyms: mesenchymal-epithelial cell signalling involved in lung development
mesenchymal-endodermal cell signaling (GO:0060497)
Namespace: biological_process
Definition: Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.
Synonyms: mesenchymal-endodermal cell signalling
obsolete retinoic acid receptor signaling pathway involved in lung bud formation (GO:0060498)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.
Synonyms: retinoic acid receptor signalling pathway involved in lung bud formation
Comment: This term was obsoleted because it is a pre-composed term that represents a GO-CAM model.
obsolete fibroblast growth factor receptor signaling pathway involved in lung induction (GO:0060499)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.
Synonyms: fibroblast growth factor receptor signalling pathway involved in lung induction
Comment: The reason for obsoletion is that these are pre-composed terms that represent a cell-surface signaling pathway during some developmental process.
obsolete regulation of transcription from RNA polymerase II promoter involved in lung bud formation (GO:0060500)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed.
Comment: This term was obsoleted because it represents a GO-CAM model.
epithelial cell proliferation involved in lung morphogenesis (GO:0060502)
Namespace: biological_process
Definition: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.
bud dilation involved in lung branching (GO:0060503)
Namespace: biological_process
Definition: The process in which a bud in the lung increases radially.
Synonyms: bud expansion
obsolete positive regulation of epithelial cell proliferation involved in lung bud dilation (GO:0060504)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete epithelial cell proliferation involved in lung bud dilation (GO:0060505)
Namespace: biological_process
Definition: OBSOLETE. The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
smoothened signaling pathway involved in lung development (GO:0060506)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.
Synonyms: hedgehog signaling pathway involved in lung development; hh signaling pathway involved in lung development; smoothened signalling pathway involved in lung development
obsolete epidermal growth factor receptor signaling pathway involved in lung development (GO:0060507)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.
Synonyms: epidermal growth factor receptor signalling pathway involved in lung development
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
lung basal cell differentiation (GO:0060508)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.
Synonyms: pulmonary basal cell differentiation
type I pneumocyte differentiation (GO:0060509)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
Synonyms: membranous pneumocyte differentiation; small alveolar cell differentiation; squamous alveolar cell differentiation
type II pneumocyte differentiation (GO:0060510)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
Synonyms: granular pneumocyte differentiation; great alveolar cell differentiation; large alveolar cell differentiation