LiteFold/GO huggingface dataset:
obsolete lysine-acetylated histone binding (GO:0070577)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a histone in which a lysine residue has been modified by acetylation.
Synonyms: acetylated histone residue binding
Comment: This term was obsoleted because it should be captured as histone reader activity ; GO:0140566 or a child.
RISC-loading complex (GO:0070578)
Namespace: cellular_component
Definition: A trimeric protein complex required for the formation of a mature RNA-induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1), TRBP (TARBP2) and the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.
Synonyms: microRNA loading complex; miRLC; RLC
DNA 5-methylcytosine dioxygenase activity (GO:0070579)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-methylcytosine (5mC) in DNA + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine (5hmC) in DNA + succinate + CO2. This reaction is the first step in the removal of cytosine methylated on position 5 in double-stranded DNA. This activity can iteratively oxidize 5hmC to 5-formylcytosine (5fC) and to 5-carboxylcytosine (5caC).
Synonyms: methylcytosine dioxygenase activity
Comment: This reaction removes the methyl group from position 5 of cytosine in DNA via oxidation of the 5-methylcytosine, followed by removal of the oxidised base by the base excision repair system. Do not confuse with oxidative DNA demethylase activity ; GO:0035516, which directly reverses the alkylation on nucleotides in the DNA.
base J metabolic process (GO:0070580)
Namespace: biological_process
Definition: The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.
Synonyms: base J metabolism; beta-D-glucosyl-HOMedU metabolic process; beta-D-glucosyl-hydroxymethyluracil metabolism
rolling circle DNA replication (GO:0070581)
Namespace: biological_process
Definition: A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.
Synonyms: rolling circle replication
theta DNA replication (GO:0070582)
Namespace: biological_process
Definition: A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.
Synonyms: theta replication
spore membrane bending pathway (GO:0070583)
Namespace: biological_process
Definition: The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.
Synonyms: ascospore-type prospore membrane bending; forespore membrane bending; FSM bending
obsolete mitochondrion morphogenesis (GO:0070584)
Namespace: biological_process
Definition: OBSOLETE. The process in which the anatomical structures of a mitochondrion are generated and organized.
Comment: This term is obsoleted because it is an unnecessary grouping term.
protein localization to mitochondrion (GO:0070585)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
Synonyms: protein localisation in mitochondrion; protein localization in mitochondrion
cell-cell adhesion involved in gastrulation (GO:0070586)
Namespace: biological_process
Definition: The attachment of one cell to another cell affecting gastrulation.
regulation of cell-cell adhesion involved in gastrulation (GO:0070587)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.
calcium ion transmembrane transport (GO:0070588)
Namespace: biological_process
Definition: A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Synonyms: calcium ion membrane transport; transmembrane calcium transport
Comment: Note that this term is not intended for use in annotating lateral movement within membranes.
obsolete cellular component macromolecule biosynthetic process (GO:0070589)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.
Synonyms: cellular component macromolecule biosynthesis
Comment: This term was obsoleted because it is an unnecessary grouping class.
spore wall biogenesis (GO:0070590)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.
cell wall polysaccharide biosynthetic process (GO:0070592)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.
Synonyms: cell wall polysaccharide anabolism; cell wall polysaccharide biosynthesis; cell wall polysaccharide synthesis
dendrite self-avoidance (GO:0070593)
Namespace: biological_process
Definition: The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
Synonyms: dendrite repulsion
(1->3)-alpha-glucan metabolic process (GO:0070595)
Namespace: biological_process
Definition: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
Synonyms: 1,3-alpha-glucan metabolic process; 1,3-alpha-glucan metabolism; alpha-1,3 glucan metabolic process; alpha-1,3 glucan metabolism
(1->3)-alpha-glucan biosynthetic process (GO:0070596)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
Synonyms: 1,3-alpha-glucan anabolism; 1,3-alpha-glucan biosynthesis; 1,3-alpha-glucan biosynthetic process; 1,3-alpha-glucan formation; 1,3-alpha-glucan synthesis; alpha-1,3 glucan anabolism; alpha-1,3 glucan biosynthesis; alpha-1,3 glucan biosynthetic process; alpha-1,3 glucan formation; alpha-1,3 glucan synthesis
cell wall (1->3)-alpha-glucan metabolic process (GO:0070597)
Namespace: biological_process
Definition: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
Synonyms: cell wall 1,3-alpha-glucan metabolic process; cell wall 1,3-alpha-glucan metabolism; cell wall alpha-1,3 glucan metabolic process; cell wall alpha-1,3 glucan metabolism
fungal-type cell wall (1->3)-alpha-glucan metabolic process (GO:0070599)
Namespace: biological_process
Definition: The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
Synonyms: ascospore wall 1,3-alpha-glucan metabolic process; ascospore wall 1,3-alpha-glucan metabolism; ascospore wall alpha-1,3 glucan metabolic process; ascospore wall alpha-1,3 glucan metabolism
fungal-type cell wall (1->3)-alpha-glucan biosynthetic process (GO:0070600)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
Synonyms: fungal-type cell wall 1,3-alpha-glucan anabolism; fungal-type cell wall 1,3-alpha-glucan biosynthesis; fungal-type cell wall 1,3-alpha-glucan biosynthetic process; fungal-type cell wall 1,3-alpha-glucan formation; fungal-type cell wall 1,3-alpha-glucan synthesis; fungal-type cell wall alpha-1,3-glucan anabolism; fungal-type cell wall alpha-1,3-glucan biosynthesis; fungal-type cell wall alpha-1,3-glucan biosynthetic process; fungal-type cell wall alpha-1,3-glucan formation; fungal-type cell wall alpha-1,3-glucan synthesis
centromeric sister chromatid cohesion (GO:0070601)
Namespace: biological_process
Definition: The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.
Synonyms: sister chromatid cohesion at centromere
regulation of centromeric sister chromatid cohesion (GO:0070602)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.
Synonyms: regulation of sister chromatid cohesion at centromere
SWI/SNF superfamily-type complex (GO:0070603)
Namespace: cellular_component
Definition: A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the catalytic subunit components (ATPase) and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
Synonyms: BAF-type complex; SWI-SNF global transcription activator complex; SWI-SNF-type complex; SWI/SNF-type complex; SWI2/SNF2 superfamily ATP-dependent chromatin remodeling complex
regulation of (1->3)-alpha-glucan biosynthetic process (GO:0070606)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
Synonyms: regulation of 1,3-alpha-glucan anabolism; regulation of 1,3-alpha-glucan biosynthesis; regulation of 1,3-alpha-glucan biosynthetic process; regulation of 1,3-alpha-glucan formation; regulation of 1,3-alpha-glucan synthesis; regulation of alpha-1,3 glucan anabolism; regulation of alpha-1,3 glucan biosynthesis; regulation of alpha-1,3 glucan biosynthetic process; regulation of alpha-1,3 glucan formation; regulation of alpha-1,3 glucan synthesis
regulation of cell wall (1->3)-alpha-glucan biosynthetic process (GO:0070608)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
Synonyms: regulation of cell wall 1,3-alpha-glucan anabolism; regulation of cell wall 1,3-alpha-glucan biosynthesis; regulation of cell wall 1,3-alpha-glucan biosynthetic process; regulation of cell wall 1,3-alpha-glucan formation; regulation of cell wall 1,3-alpha-glucan synthesis; regulation of cell wall alpha-1,3-glucan anabolism; regulation of cell wall alpha-1,3-glucan biosynthesis; regulation of cell wall alpha-1,3-glucan biosynthetic process; regulation of cell wall alpha-1,3-glucan formation; regulation of cell wall alpha-1,3-glucan synthesis
obsolete regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process (GO:0070609)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
Synonyms: regulation of ascospore wall 1,3-alpha-glucan metabolism; regulation of ascospore wall alpha-1,3 glucan metabolic process; regulation of ascospore wall alpha-1,3 glucan metabolism; regulation of fungal-type cell wall 1,3-alpha-glucan metabolic process
Comment: This term was obsoleted because it is an unnecessary grouping class.
regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process (GO:0070610)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
Synonyms: regulation of fungal type cell wall 1,3-alpha-glucan biosynthetic process; regulation of fungal-type cell wall 1,3-alpha-glucan anabolism; regulation of fungal-type cell wall 1,3-alpha-glucan biosynthesis; regulation of fungal-type cell wall 1,3-alpha-glucan formation; regulation of fungal-type cell wall 1,3-alpha-glucan synthesis; regulation of fungal-type cell wall alpha-1,3-glucan anabolism; regulation of fungal-type cell wall alpha-1,3-glucan biosynthesis; regulation of fungal-type cell wall alpha-1,3-glucan biosynthetic process; regulation of fungal-type cell wall alpha-1,3-glucan formation; regulation of fungal-type cell wall alpha-1,3-glucan synthesis
histone H2AR3 methyltransferase activity (GO:0070612)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H2A.
Synonyms: histone H2AR3 arginine methyltransferase activity; histone methylase activity (H2A-R3 specific); histone methyltransferase activity (H2A-R3 specific); histone-arginine N-methyltransferase activity (H2A-R3 specific); histone-H2AR3 methyltransferase activity
Comment: Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue seems to be only present in animals. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
regulation of protein processing (GO:0070613)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein processing, a protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
Synonyms: regulation of protein maturation by peptide bond cleavage
tungstate ion transport (GO:0070614)
Namespace: biological_process
Definition: The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.
regulation of thiamine diphosphate biosynthetic process (GO:0070616)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
Synonyms: regulation of thiamin diphosphate biosynthetic process; regulation of thiamine diphosphate anabolism; regulation of thiamine diphosphate biosynthesis; regulation of thiamine diphosphate formation; regulation of thiamine diphosphate synthesis
negative regulation of thiamine diphosphate biosynthetic process (GO:0070617)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
Synonyms: down regulation of thiamine diphosphate biosynthetic process; down-regulation of thiamine diphosphate biosynthetic process; downregulation of thiamine diphosphate biosynthetic process; inhibition of thiamine diphosphate biosynthetic process; negative regulation of thiamin diphosphate biosynthetic process; negative regulation of thiamine diphosphate anabolism; negative regulation of thiamine diphosphate biosynthesis; negative regulation of thiamine diphosphate formation; negative regulation of thiamine diphosphate synthesis
Grb2-Sos complex (GO:0070618)
Namespace: cellular_component
Definition: A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms: Grb2-mSos1 complex
Shc-Grb2-Sos complex (GO:0070619)
Namespace: cellular_component
Definition: A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms: Shc-Grb2-mSos1 complex, EGF stimulated
EGFR-Grb2-Sos complex (GO:0070620)
Namespace: cellular_component
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms: Egfr-Grb2-mSos1 complex, EGF stimulated
EGFR-Shc-Grb2-Sos complex (GO:0070621)
Namespace: cellular_component
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex (GO:0070622)
Namespace: cellular_component
Definition: A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.
Synonyms: N-acetylglucosamine-1-phosphotransferase complex; UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase complex
regulation of thiamine biosynthetic process (GO:0070623)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
Synonyms: regulation of thiamin biosynthetic process; regulation of thiamine anabolism; regulation of thiamine biosynthesis; regulation of thiamine formation; regulation of thiamine synthesis
negative regulation of thiamine biosynthetic process (GO:0070624)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
Synonyms: down regulation of thiamine biosynthetic process; down-regulation of thiamine biosynthetic process; downregulation of thiamine biosynthetic process; inhibition of thiamine biosynthetic process; negative regulation of thiamin biosynthetic process; negative regulation of thiamine anabolism; negative regulation of thiamine biosynthesis; negative regulation of thiamine formation; negative regulation of thiamine synthesis
zymogen granule exocytosis (GO:0070625)
Namespace: biological_process
Definition: The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.
(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (GO:0070626)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
Synonyms: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity; adenylosuccinase activity; adenylosuccinate lyase activity; SAICAR-lyase (fumarate forming) activity; succino AMP-lyase activity
proteasome binding (GO:0070628)
Namespace: molecular_function
Definition: Binding to a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
(1->4)-alpha-glucan metabolic process (GO:0070629)
Namespace: biological_process
Definition: The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
Synonyms: (1->4)-alpha-D-glucan metabolism; 1,4-alpha-D-glucan metabolism; 1,4-alpha-glucan metabolism; alpha-1,4 glucan metabolic process; alpha-1,4 glucan metabolism
(1->4)-alpha-glucan biosynthetic process (GO:0070630)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
Synonyms: (1->4)-alpha-D-glucan anabolism; (1->4)-alpha-D-glucan biosynthesis; (1->4)-alpha-D-glucan formation; (1->4)-alpha-D-glucan synthesis; 1,4-alpha-glucan anabolism; 1,4-alpha-glucan biosynthesis; 1,4-alpha-glucan biosynthetic process; 1,4-alpha-glucan formation; 1,4-alpha-glucan synthesis; alpha-1,4 glucan anabolism; alpha-1,4 glucan biosynthesis; alpha-1,4 glucan biosynthetic process; alpha-1,4 glucan formation; alpha-1,4 glucan synthesis
spindle pole body localization (GO:0070631)
Namespace: biological_process
Definition: Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
Synonyms: maintenance of spindle pole body localization; spindle pole body localisation
transepithelial transport (GO:0070633)
Namespace: biological_process
Definition: The directed movement of a substance from one side of an epithelium to the other.
nicotinamide riboside hydrolase activity (GO:0070635)
Namespace: molecular_function
Definition: Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
Synonyms: N-ribosylnicotinamide hydrolase activity; nicotinamide ribonucleoside hydrolase activity
nicotinic acid riboside hydrolase activity (GO:0070636)
Namespace: molecular_function
Definition: Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
Synonyms: D-ribosylnicotinate hydrolase activity; D-ribosylnicotinic acid hydrolase activity; nicotinate ribonucleoside hydrolase activity; nicotinate riboside hydrolase activity; nicotinic acid ribonucleoside hydrolase activity
pyridine nucleoside metabolic process (GO:0070637)
Namespace: biological_process
Definition: The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
Synonyms: pyridine nucleoside metabolism
pyridine nucleoside catabolic process (GO:0070638)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
Synonyms: pyridine nucleoside breakdown; pyridine nucleoside catabolism; pyridine nucleoside degradation
obsolete vitamin D2 metabolic process (GO:0070639)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.
Synonyms: calciferol metabolic process; ergocalciferol metabolic process; vitamin D2 metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
vitamin D3 metabolic process (GO:0070640)
Namespace: biological_process
Definition: The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
Synonyms: calciol metabolic process; cholecalciferol metabolic process; vitamin D3 metabolism