LiteFold/GO huggingface dataset:
obsolete regulation of cAMP-mediated signaling (GO:0043949)
Namespace: biological_process
Definition: OBSOLETE. Any process which modulates the frequency, rate or extent of cAMP-mediated signaling.
Synonyms: regulation of cAMP-mediated signalling
Comment: This term was obsoleted because it does not represent regulation of a specific pathway. Consider regulation of cAMP/PKA signal transduction ; GO:0141161, or regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0106070.
obsolete positive regulation of cAMP-mediated signaling (GO:0043950)
Namespace: biological_process
Definition: OBSOLETE. Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling.
Synonyms: positive regulation of cAMP-mediated signalling
Comment: This term was obsoleted because it does not represent regulation of a specific pathway. Consider positive regulation of cAMP/PKA signal transduction ; GO:0141163, or positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0106071.
obsolete negative regulation of cAMP-mediated signaling (GO:0043951)
Namespace: biological_process
Definition: OBSOLETE. Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling.
Synonyms: negative regulation of cAMP-mediated signalling
Comment: This term was obsoleted because it does not represent regulation of a specific pathway. Consider negative regulation of cAMP/PKA signal transduction ; GO:0141162, or negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0106072.
protein transport by the Sec complex (GO:0043952)
Namespace: biological_process
Definition: The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
Synonyms: protein secretion by the Sec complex; protein translocation by the Sec complex
Comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'protein secretion by the type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.
protein transport by the Tat complex (GO:0043953)
Namespace: biological_process
Definition: The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.
Synonyms: protein secretion by the TAT complex; protein translocation by the TAT complex; protein translocation by the twin-arginine translocation complex; twin-arginine translocation pathway
Comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'TAT protein translocation system complex ; GO:0033281'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.
cellular component maintenance (GO:0043954)
Namespace: biological_process
Definition: The organization process that preserves a cellular component in a stable functional or structural state.
Synonyms: cellular component maintenance at cellular level
3-hydroxypropionyl-CoA synthetase activity (GO:0043955)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.
Synonyms: 3-hydroxy propionyl-CoA synthetase activity; acetyl-coenzyme A synthetase; acetyl-coenzyme A synthetase/GroES-like domain; AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase
Comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.
acryloyl-CoA reductase (NADPH) activity (GO:0043957)
Namespace: molecular_function
Definition: Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.
Synonyms: acetyl-coenzyme A synthetase; acetyl-coenzyme A synthetase/GroES-like domain; acrylyl-CoA reductase (NADPH) activity; AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase:enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase
Comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.
acryloyl-CoA reductase (NADH) activity (GO:0043958)
Namespace: molecular_function
Definition: Catalysis of the reaction: propanoyl-CoA + NAD+ = acryloyl-CoA + H+ + NADH.
Synonyms: acryloyl-CoA reductase activity; acryloyl-coenzyme A reductase activity; acrylyl-CoA reductase (NADH); propionyl-CoA dehydrogenase
Comment: Note that this function is part of the process of L-alanine fermentation to propionate.
L-erythro-3-methylmalyl-CoA lyase activity (GO:0043959)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2R,3S)-beta-methylmalyl-CoA = glyoxylate + propanoyl-CoA.
Synonyms: HpcH/HpaI aldolase
obsolete L-erythro-3-methylmalyl-CoA dehydratase activity (GO:0043960)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O.
Comment: This term was obsoleted because it represents a specific substrate.
succinyl-CoA:(R)-citramalate CoA-transferase activity (GO:0043961)
Namespace: molecular_function
Definition: Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.
Synonyms: L-carnitine dehydratase/bile acid-inducible protein F; succinyl-CoA:(R)-citramalate CoA transferase activity; succinyl-CoA:R-citramalate CoA transferase
obsolete negative regulation by host of symbiont adenylate cyclase-mediated signal transduction (GO:0043962)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: The reason for obsoletion is that there is no evidence that the host can modulate or regulate a symbiont's signal transduction pathway.
obsolete perturbation of host adenylate cyclase-mediated signal transduction (GO:0043963)
Namespace: biological_process
Definition: OBSOLETE. A process in which a symbiont alters or subverts an adenylate cyclase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because it is redundant with other terms: 'symbiont-mediated cAMP intoxication of host cell ; GO:0141042' and 'perturbation of host G protein-coupled receptor signal transduction pathway ; GO:0075118'.
obsolete induction by symbiont of host adenylate cyclase-mediated signal transduction (GO:0043964)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: positive regulation by symbiont of host adenylate cyclase-mediated signal transduction
Comment: This term was obsoleted because the process it represents it does not exist; this corresponds to a host response to a pathogenic symbiont.
obsolete symbiont-mediated suppression of host adenylate cyclase-mediated signal transduction (GO:0043965)
Namespace: biological_process
Definition: OBSOLETE. A process in which a virus interferes with, inhibits or disrupts an adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: disruption of host adenylate cyclase-mediated signal transduction; negative regulation by symbiont of host adenylate cyclase-mediated signal transduction; suppression by symbiont of host adenylate cyclase-mediated signal transduction
Comment: This term was obsoleted because it is redundant with other terms: 'symbiont-mediated cAMP intoxication of host cell ; GO:0141042' and 'perturbation of host G protein-coupled receptor signal transduction pathway ; GO:0075118'.
obsolete histone H4 acetylation (GO:0043967)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an acetyl group.
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2A acetylation (GO:0043968)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2A by the addition of an acetyl group.
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2B acetylation (GO:0043969)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2B by the addition of an acetyl group.
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K9 acetylation (GO:0043970)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.
Synonyms: histone H3 acetylation at K9; histone H3K9 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K18 acetylation (GO:0043971)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.
Synonyms: histone H3 acetylation at K18; histone H3K18 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K23 acetylation (GO:0043972)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone.
Synonyms: histone H3 acetylation at K23; histone H3K23 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K4 acetylation (GO:0043973)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.
Synonyms: histone H3 acetylation at K4; histone H3K4 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K27 acetylation (GO:0043974)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone.
Synonyms: histone H3 acetylation at K27; histone H3K27 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K36 acetylation (GO:0043975)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone.
Synonyms: histone H3 acetylation at K36; histone H3K36 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K79 acetylation (GO:0043976)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone.
Synonyms: histone H3 acetylation at K79; histone H3K79 acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2A-K5 acetylation (GO:0043977)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone.
Synonyms: histone H2A acetylation at K5
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2A-K9 acetylation (GO:0043978)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone.
Synonyms: histone H2A acetylation at K9
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2B-K5 acetylation (GO:0043979)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.
Synonyms: histone H2B acetylation at K5
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2B-K12 acetylation (GO:0043980)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone.
Synonyms: histone H2B acetylation at K12
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-K5 acetylation (GO:0043981)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
Synonyms: histone H4 acetylation at K5
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-K8 acetylation (GO:0043982)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
Synonyms: histone H4 acetylation at K8
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-K16 acetylation (GO:0043984)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.
Synonyms: histone H4 acetylation at K16
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-R3 methylation (GO:0043985)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone.
Synonyms: histone H4 methylation at R3; histone H4 R3 methylation; histone H4R3me
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-S10 phosphorylation (GO:0043987)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone.
Synonyms: histone H3 phosphorylation at S10; histone H3S10 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-S28 phosphorylation (GO:0043988)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone.
Synonyms: histone H3 phosphorylation at S28; histone H3S28 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-S1 phosphorylation (GO:0043989)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone.
Synonyms: histone H4 phosphorylation at S1; histone H4S1 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2A-S1 phosphorylation (GO:0043990)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone.
Synonyms: histone H2A phosphorylation at S1; histone H2AS1 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H2B-S14 phosphorylation (GO:0043991)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone.
Synonyms: histone H2B phosphorylation at S14; histone H2BS14 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
histone H3K9 acetyltransferase activity (GO:0043992)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).
Synonyms: histone acetylase activity (H3-K9 specific); histone acetyltransferase activity (H3-K9 specific); histone H3-K9 acetyltransferase activity; histone lysine N-acetyltransferase activity (H3-K9 specific)
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
histone H3K18 acetyltransferase activity (GO:0043993)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).
Synonyms: histone acetylase activity (H3-K18 specific); histone acetyltransferase activity (H3-K18 specific); histone H3-K18 acetyltransferase activity; histone lysine N-acetyltransferase activity (H3-K18 specific)
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
histone H3K23 acetyltransferase activity (GO:0043994)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).
Synonyms: histone acetylase activity (H3-K23 specific); histone acetyltransferase activity (H3-K23 specific); histone H3-K23 acetyltransferase activity; histone lysine N-acetyltransferase activity (H3-K23 specific)
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
histone H4K5 acetyltransferase activity (GO:0043995)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).
Synonyms: histone acetylase activity (H4-K5 specific); histone acetyltransferase activity (H4-K5 specific); histone lysine N-acetyltransferase activity (H4-K5 specific)
Comment: Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
histone H4K8 acetyltransferase activity (GO:0043996)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).
Synonyms: histone acetylase activity (H4-K8 specific); histone acetyltransferase activity (H4-K8 specific); histone lysine N-acetyltransferase activity (H4-K8 specific)
Comment: Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
histone H4K12 acetyltransferase activity (GO:0043997)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).
Synonyms: histone acetylase activity (H4-K12 specific); histone acetyltransferase activity (H4-K12 specific); histone H4-K12 acetyltransferase activity; histone lysine N-acetyltransferase activity (H4-K12 specific)
Comment: Note that the residue position corresponds to the canonical human H4 histone (UniProtKB:P02309); this residue is conserved across all eukaryotes. Note that the initiation methionine is cleaved, so the first residue is S1.
histone H2A acetyltransferase activity (GO:0043998)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
Synonyms: H2A histone acetylase activity; H2A histone acetyltransferase activity; H2A histone lysine N-acetyltransferase activity
histone H2AK5 acetyltransferase activity (GO:0043999)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).
Synonyms: histone acetylase activity (H2A-K5 specific); histone acetyltransferase activity (H2A-K5 specific); histone H2A-K5 acetyltransferase activity; histone lysine N-acetyltransferase activity (H2A-K5 specific)
Comment: Note that the residue position corresponds to the canonical human H2A2A histone (UniProtKB:Q6FI13); this residue is conserved across all eukaryotes. Corresponds to H2AK4 in yeast and in flies. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
obsolete movement in host (GO:0044000)
Namespace: biological_process
Definition: OBSOLETE. The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: movement in host environment; movement of symbiont in host; movement of symbiont within host; movement within host; symbiont movement in host; symbiont movement within host
Comment: This term was obsoleted because it is an unnecessary grouping term.
migration in host (GO:0044001)
Namespace: biological_process
Definition: The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: migration within host
acquisition of nutrients from host (GO:0044002)
Namespace: biological_process
Definition: The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
symbiont-mediated perturbation of host process (GO:0044003)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts a biological process in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: disruption by symbiont of host cell; modification by symbiont of host biological process; modification by symbiont of host morphology or physiology; modulation by symbiont of host system process; pathogenesis; regulation by symbiont of host system process