LiteFold/GO huggingface dataset:
negative regulation of release of sequestered calcium ion into cytosol (GO:0051280)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms: down regulation of release of sequestered calcium ion into cytosol; down-regulation of release of sequestered calcium ion into cytosol; downregulation of release of sequestered calcium ion into cytosol; inhibition of release of sequestered calcium ion into cytosol; negative regulation of calcium ion (Ca2+) mobilization; negative regulation of calcium mobilization; negative regulation of cytoplasmic release of sequestered calcium ion (Ca2+); negative regulation of cytoplasmic release of stored calcium ion (Ca2+); negative regulation of cytosolic release of sequestered calcium ion (Ca2+); negative regulation of cytosolic release of stored calcium ion (Ca2+); negative regulation of release of sequestered calcium ion (Ca2+); negative regulation of release of sequestered calcium ion into cytoplasm; negative regulation of release of stored calcium ion (Ca2+); negative regulation of release of stored calcium ion (Ca2+) into cytoplasm; negative regulation of release of stored calcium ion (Ca2+) into cytosol
positive regulation of release of sequestered calcium ion into cytosol (GO:0051281)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
Synonyms: activation of release of sequestered calcium ion into cytosol; positive regulation of calcium ion (Ca2+) mobilization; positive regulation of calcium mobilization; positive regulation of cytoplasmic release of sequestered calcium ion (Ca2+); positive regulation of cytoplasmic release of stored calcium ion (Ca2+); positive regulation of cytosolic release of sequestered calcium ion (Ca2+); positive regulation of cytosolic release of stored calcium ion (Ca2+); positive regulation of release of sequestered calcium ion (Ca2+); positive regulation of release of sequestered calcium ion into cytoplasm; positive regulation of release of stored calcium ion (Ca2+); positive regulation of release of stored calcium ion (Ca2+) into cytoplasm; positive regulation of release of stored calcium ion (Ca2+) into cytosol; stimulation of release of sequestered calcium ion into cytosol; up regulation of release of sequestered calcium ion into cytosol; up-regulation of release of sequestered calcium ion into cytosol; upregulation of release of sequestered calcium ion into cytosol
obsolete negative regulation of sequestering of calcium ion (GO:0051283)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
Synonyms: down regulation of sequestering of calcium ion; down-regulation of sequestering of calcium ion; downregulation of sequestering of calcium ion; inhibition of sequestering of calcium ion; negative regulation of calcium ion (Ca2+) retention; negative regulation of calcium ion (Ca2+) sequestering; negative regulation of calcium ion (Ca2+) sequestration; negative regulation of calcium ion (Ca2+) storage; negative regulation of retention of calcium ion (Ca2+); negative regulation of sequestering of calcium ion (Ca2+); negative regulation of sequestration of calcium ion (Ca2+); negative regulation of storage of calcium ion (Ca2+)
Comment: The reason for obsoletion is that this term represents a molecular function and not a real GO process.
obsolete positive regulation of sequestering of calcium ion (GO:0051284)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
Synonyms: activation of sequestering of calcium ion; positive regulation of calcium ion (Ca2+) retention; positive regulation of calcium ion (Ca2+) sequestering; positive regulation of calcium ion (Ca2+) sequestration; positive regulation of calcium ion (Ca2+) storage; positive regulation of retention of calcium ion (Ca2+); positive regulation of sequestering of calcium ion (Ca2+); positive regulation of sequestration of calcium ion (Ca2+); positive regulation of storage of calcium ion (Ca2+); stimulation of sequestering of calcium ion; up regulation of sequestering of calcium ion; up-regulation of sequestering of calcium ion; upregulation of sequestering of calcium ion
Comment: The reason for obsoletion is that this term represents a molecular function and not a real GO process.
cell cortex of cell tip (GO:0051285)
Namespace: cellular_component
Definition: The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
Synonyms: cell cortex of cell end
cell tip (GO:0051286)
Namespace: cellular_component
Definition: The region at the end of the longest axis of a cylindrical or elongated cell.
Synonyms: cell end
Comment: Note that this term differs from 'cell pole ; GO:0060187' in that it is applicable to the thin ends of elongated cells, such as the ends of axons or dendrites.
NAD binding (GO:0051287)
Namespace: molecular_function
Definition: Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
Synonyms: NAD or NADH binding; NAD+ or NADH binding; nicotinamide adenine dinucleotide binding
protein homotetramerization (GO:0051289)
Namespace: biological_process
Definition: The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
Synonyms: protein homotetramer assembly; protein homotetramer biosynthesis; protein homotetramer biosynthetic process; protein homotetramer formation
protein heterotetramerization (GO:0051290)
Namespace: biological_process
Definition: The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
Synonyms: protein heterotetramer assembly; protein heterotetramer biosynthesis; protein heterotetramer biosynthetic process; protein heterotetramer formation
establishment of spindle localization (GO:0051293)
Namespace: biological_process
Definition: The directed movement of the spindle to a specific location in the cell.
Synonyms: establishment of spindle localisation; spindle positioning
establishment of spindle orientation (GO:0051294)
Namespace: biological_process
Definition: Any process that set the alignment of spindle relative to other cellular structures.
Synonyms: orienting of spindle; spindle orientation
establishment of meiotic spindle orientation (GO:0051296)
Namespace: biological_process
Definition: Any process that set the alignment of meiotic spindle relative to other cellular structures.
Synonyms: establishment of spindle orientation during meiosis; establishment of spindle orientation involved in meiotic cell cycle; meiotic spindle orientation; orienting of meiotic spindle
centrosome duplication (GO:0051298)
Namespace: biological_process
Definition: The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
Synonyms: centrosome replication
centrosome separation (GO:0051299)
Namespace: biological_process
Definition: The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
spindle pole body organization (GO:0051300)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.
Synonyms: SPB maturation; SPB organization; spindle pole body maturation; spindle pole body organisation; spindle pole body organization and biogenesis
cell division (GO:0051301)
Namespace: biological_process
Definition: The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
Comment: Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division.
regulation of cell division (GO:0051302)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
obsolete establishment of chromosome localization (GO:0051303)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of a chromosome to a specific location.
Synonyms: chromosome positioning; establishment of chromosome localisation
Comment: The reason for obsoletion is that more specific terms were created.
chromosome separation (GO:0051304)
Namespace: biological_process
Definition: The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
Synonyms: chromatid release; rDNA separation
chromosome movement towards spindle pole (GO:0051305)
Namespace: biological_process
Definition: The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.
Synonyms: chromosome migration to spindle pole; chromosome movement; chromosome movement to spindle pole
mitotic sister chromatid separation (GO:0051306)
Namespace: biological_process
Definition: The process in which sister chromatids are physically detached from each other during mitosis.
Synonyms: chromosome separation during mitosis; mitotic chromosome separation; mitotic sister chromatid resolution; sister chromatid separation during mitosis
male meiosis chromosome separation (GO:0051308)
Namespace: biological_process
Definition: The process in which paired chromosomes are physically detached from each other during male meiosis.
Synonyms: chromosome separation during male meiosis; male meiosis chromosome resolution
female meiosis chromosome separation (GO:0051309)
Namespace: biological_process
Definition: The process in which paired chromosomes are physically detached from each other during female meiosis.
Synonyms: chromosome separation during female meiosis; female meiosis chromosome resolution
metaphase chromosome alignment (GO:0051310)
Namespace: biological_process
Definition: A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
Synonyms: chromosome congression
obsolete chromosome decondensation (GO:0051312)
Namespace: biological_process
Definition: OBSOLETE. The alteration of chromosome structure from the condensed form to a relaxed disperse form.
Comment: This term was obsoleted because it is a spontaneous process.
attachment of mitotic spindle microtubules to kinetochore (GO:0051315)
Namespace: biological_process
Definition: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.
Synonyms: attachment of spindle microtubules to kinetochore during mitosis; attachment of spindle microtubules to kinetochore involved in mitosis; attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; attachment of spindle microtubules to mitotic chromosome; mitotic bipolar attachment
Comment: This class covers transient, lateral attachment to microtubules as well as stable, correctly oriented, end-on attachment (biorientation)
attachment of meiotic spindle microtubules to kinetochore (GO:0051316)
Namespace: biological_process
Definition: The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in meiosis.
Synonyms: attachment of spindle microtubules to kinetochore during meiosis; attachment of spindle microtubules to kinetochore during meiotic chromosome segregation; attachment of spindle microtubules to meiotic chromosome
G1 phase (GO:0051318)
Namespace: biological_process
Definition: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
G2 phase (GO:0051319)
Namespace: biological_process
Definition: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
S phase (GO:0051320)
Namespace: biological_process
Definition: The cell cycle phase, following G1, during which DNA synthesis takes place.
Synonyms: S-phase
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic cell cycle (GO:0051321)
Namespace: biological_process
Definition: Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
Synonyms: meiosis
Comment: Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle.
anaphase (GO:0051322)
Namespace: biological_process
Definition: The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
metaphase (GO:0051323)
Namespace: biological_process
Definition: The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
prophase (GO:0051324)
Namespace: biological_process
Definition: The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
interphase (GO:0051325)
Namespace: biological_process
Definition: The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
Synonyms: karyostasis; resting phase
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
telophase (GO:0051326)
Namespace: biological_process
Definition: The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
Comment: note that this term should not be used for direct annotation. if you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic s-phase). to capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic M phase (GO:0051327)
Namespace: biological_process
Definition: A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
Synonyms: M phase of meiotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic interphase (GO:0051328)
Namespace: biological_process
Definition: The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
Synonyms: interphase of meiotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic interphase (GO:0051329)
Namespace: biological_process
Definition: The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
Synonyms: interphase of mitotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic G1 phase (GO:0051330)
Namespace: biological_process
Definition: The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.
Synonyms: G1 phase of meiotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).