LiteFold/GO huggingface dataset:
2-(3-amino-3-carboxypropyl)histidine synthase activity (GO:0090560)
Namespace: molecular_function
Definition: Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].
nuclear migration during mitotic telophase (GO:0090561)
Namespace: biological_process
Definition: The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.
protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity (GO:0090562)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).
protein-phosphocysteine-sugar phosphotransferase activity (GO:0090563)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
protein-phosphocysteine-glucose phosphotransferase system transporter activity (GO:0090564)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
protein-phosphocysteine-mannitol phosphotransferase system transporter activity (GO:0090565)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
reproductive shoot system development (GO:0090567)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.
RNA polymerase I transcription repressor complex (GO:0090570)
Namespace: cellular_component
Definition: A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.
RNA polymerase III transcription repressor complex (GO:0090572)
Namespace: cellular_component
Definition: A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.
RNA polymerase IV transcription repressor complex (GO:0090573)
Namespace: cellular_component
Definition: A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.
RNA polymerase II transcription regulator complex (GO:0090575)
Namespace: cellular_component
Definition: A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase II.
Synonyms: RNA polymerase II transcription factor complex
RNA polymerase III transcription regulator complex (GO:0090576)
Namespace: cellular_component
Definition: A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase III.
Synonyms: RNA polymerase III transcription factor complex
RNA polymerase IV transcription regulator complex (GO:0090577)
Namespace: cellular_component
Definition: A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.
Synonyms: RNA polymerase IV transcription factor complex
obsolete dsDNA loop formation (GO:0090579)
Namespace: biological_process
Definition: OBSOLETE. The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule.
Synonyms: chromatin looping; dsDNA looping
Comment: This term was obsoleted because it was defined like a molecular function.
phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands (GO:0090580)
Namespace: molecular_function
Definition: Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated DNA strand.
protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity (GO:0090581)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).
protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity (GO:0090582)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).
protein-phosphocysteine-galactitol-phosphotransferase system transporter activity (GO:0090584)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).
protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity (GO:0090585)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).
protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity (GO:0090586)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).
protein-phosphocysteine-glucosamine phosphotransferase system transporter activity (GO:0090587)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).
protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity (GO:0090588)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).
protein-phosphocysteine-trehalose phosphotransferase system transporter activity (GO:0090589)
Namespace: molecular_function
Definition: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).
obsolete protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity (GO:0090590)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).
Comment: This term was obsoleted because it represents a specific substrate of protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity ; GO:0022870 (see PMID:8246840).
DNA synthesis involved in DNA replication (GO:0090592)
Namespace: biological_process
Definition: Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.
obsolete peptidyl-histidine autophosphorylation (GO:0090593)
Namespace: biological_process
Definition: OBSOLETE. The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.
Comment: This term was obsoleted because it represents a molecular function.
inflammatory response to wounding (GO:0090594)
Namespace: biological_process
Definition: The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.
nematode male tail mating organ morphogenesis (GO:0090597)
Namespace: biological_process
Definition: The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.
male anatomical structure morphogenesis (GO:0090598)
Namespace: biological_process
Definition: The processes by which anatomical structures that are only present in the male organism are generated and organized.
alpha-glucosidase activity (GO:0090599)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.
obsolete alpha-1,3-glucosidase activity (GO:0090600)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose.
Comment: This term was obsoleted because it was an unnecessary grouping term.
enucleation (GO:0090601)
Namespace: biological_process
Definition: The process in which nucleated precursor cells lose their nucleus.
sieve element enucleation (GO:0090602)
Namespace: biological_process
Definition: The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.
sieve element differentiation (GO:0090603)
Namespace: biological_process
Definition: The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.
surface biofilm formation (GO:0090604)
Namespace: biological_process
Definition: A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
submerged biofilm formation (GO:0090605)
Namespace: biological_process
Definition: A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
Synonyms: solid substrate biofilm formation
single-species surface biofilm formation (GO:0090606)
Namespace: biological_process
Definition: A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.
Synonyms: multicellular pellicle formation
single-species submerged biofilm formation (GO:0090609)
Namespace: biological_process
Definition: A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
bundle sheath cell fate specification (GO:0090610)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway (GO:0090611)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
cAMP deaminase activity (GO:0090612)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3',5'-cyclic AMP + H2O + H+ = 3',5'-cyclic IMP + NH4+.
Synonyms: cyclic adenosine monophosphate deaminase activity
5'-deoxyadenosine deaminase activity (GO:0090613)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5'-deoxyadenosine + H2O + H+ = 5'-deoxyinosine + NH4+.
5'-methylthioadenosine deaminase activity (GO:0090614)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-methyl-5'-thioadenosine + H2O + H+ = S-methyl-5'-thioinosine + NH4+.
mitochondrial mRNA processing (GO:0090615)
Namespace: biological_process
Definition: Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
mitochondrial mRNA 3'-end processing (GO:0090616)
Namespace: biological_process
Definition: Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.
mitochondrial mRNA 5'-end processing (GO:0090617)
Namespace: biological_process
Definition: Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.
obsolete DNA clamp unloading (GO:0090618)
Namespace: biological_process
Definition: OBSOLETE. The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates.
Synonyms: PCNA unloading
Comment: This term was obsoleted because it represents a molecular function.
meiotic spindle pole (GO:0090619)
Namespace: cellular_component
Definition: Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
obsolete APC-Cdc20 complex (GO:0090620)
Namespace: cellular_component
Definition: OBSOLETE. An anaphase promoting complex bound to the fizzy family APC activator Cdc20/Slp1 which regulates the metaphase anaphase transition by activating the APC/C to target the anaphase inhibitor securin and promotes sister chromatid separation.
Synonyms: APC-fizzy complex; APC-Slp1 complex; mitotic anaphase promotic complex
Comment: This term was made obsolete because it is too fine-grained for GO. Consider Complex Portal EBI-1252490, Anaphase-Promoting Complex variant 2 as an alternate term.
obsolete APC-fizzy-related complex (GO:0090621)
Namespace: cellular_component
Definition: OBSOLETE. An anaphase promoting complex bound to the fizzy-related family APC activator FZR1/Cdh1/Srw1 that regulates mitotic exit by activating the APC/C to target mitotic cyclins for destruction during anaphase and telophase. Is also active during G1.
Synonyms: APC-Hct1/Cdh1 complex; APC-Srw1 complex
Comment: This term was made obsolete because it is too fine-grained for GO.
endoribonuclease activity, cleaving miRNA-paired mRNA (GO:0090624)
Namespace: molecular_function
Definition: Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.
siRNA-mediated gene silencing by mRNA destabilization (GO:0090625)
Namespace: biological_process
Definition: An siRNA-mediated post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
Synonyms: gene silencing by mRNA cleavage; mRNA cleavage involved in gene silencing by siRNA; mRNA destabilization-mediated gene silencing by siRNA
plant epidermis morphogenesis (GO:0090626)
Namespace: biological_process
Definition: The process in which the anatomical structures of the plant epidermis are generated and organized.
plant epidermal cell differentiation (GO:0090627)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.
plant epidermal cell fate specification (GO:0090628)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
lagging strand initiation (GO:0090629)
Namespace: biological_process
Definition: The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.
activation of GTPase activity (GO:0090630)
Namespace: biological_process
Definition: Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
Synonyms: activation of ARF GTPase activity; activation of Cdc42 GTPase activity; activation of Rab GTPase activity; activation of Rac GTPase activity; activation of Ral GTPase activity; activation of Ran GTPase activity; activation of Rap GTPase activity; activation of Ras GTPase activity; activation of Rho GTPase activity; ARF GTPase activation; Cdc42 GTPase activation; Rab GTPase activation; Rac GTPase activation; Ral GTPase activation; Ran GTPase activation; Rap GTPase activation; Ras GTPase activation; Rho GTPase activation
N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity (GO:0090632)
Namespace: molecular_function
Definition: Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.
Synonyms: CMP-Neu5Gc synthetase activity
keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity (GO:0090633)
Namespace: molecular_function
Definition: Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.
Synonyms: CMP-KDN synthetase activity; cytidine 5'-monophospho-2-Keto-3-deoxy-D-glycero-D-galacto-nononic acid synthetase activity
microglial cell mediated cytotoxicity (GO:0090634)
Namespace: biological_process
Definition: The directed killing of a target cell by a microglial cell.
extracellular core region of desmosome (GO:0090635)
Namespace: cellular_component
Definition: The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.
Synonyms: desmoglea
outer dense plaque of desmosome (GO:0090636)
Namespace: cellular_component
Definition: The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.
inner dense plaque of desmosome (GO:0090637)
Namespace: cellular_component
Definition: The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.
phosphatidylcholine biosynthesis from phosphatidylethanolamine (GO:0090638)
Namespace: biological_process
Definition: The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations.
phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol (GO:0090639)
Namespace: biological_process
Definition: The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.
phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine (GO:0090640)
Namespace: biological_process
Definition: The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.
microsporidian-type endospore (GO:0090641)
Namespace: cellular_component
Definition: The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.
Comment: Microsporidian biology uses the term endospore differently than GO:0043593 endospore coat which is for a spore formed inside of another cell. Microsporidian endospore refers to the inner layer of the spore wall itself.
microsporidian-type exospore (GO:0090642)
Namespace: cellular_component
Definition: The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.
inflorescence phyllotactic patterning (GO:0090643)
Namespace: biological_process
Definition: The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.
age-related resistance (GO:0090644)
Namespace: biological_process
Definition: An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).
Synonyms: adult seedling resistance; ARR; developmental resistance; flowering-induced resistance; mature seedling resistance; ontogenic resistance; senescence-induced resistance
mitochondrial tRNA processing (GO:0090646)
Namespace: biological_process
Definition: The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
obsolete modulation of age-related behavioral decline (GO:0090647)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.
Comment: This term was obsoleted because it represents a phenotype.
response to environmental enrichment (GO:0090648)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.
Synonyms: response to the introduction of novel objects
response to oxygen-glucose deprivation (GO:0090649)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
Synonyms: response to OGD
cellular response to oxygen-glucose deprivation (GO:0090650)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
Synonyms: cellular response to OGD
apical cytoplasm (GO:0090651)
Namespace: cellular_component
Definition: The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.