LiteFold/GO huggingface dataset:
positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
Synonyms: activation of CD4-positive, alpha beta T cell differentiation; positive regulation of CD4-positive T lymphocyte differentiation; positive regulation of CD4-positive T-cell differentiation; positive regulation of CD4-positive T-lymphocyte differentiation; positive regulation of CD4-positive, alpha beta T cell development; positive regulation of CD4-positive, alpha beta T cell differentiation; positive regulation of CD4-positive, alpha beta T lymphocyte differentiation; positive regulation of CD4-positive, alpha beta T-cell differentiation; positive regulation of CD4-positive, alpha beta T-lymphocyte differentiation; stimulation of CD4-positive, alpha beta T cell differentiation; up regulation of CD4-positive, alpha beta T cell differentiation; up-regulation of CD4-positive, alpha beta T cell differentiation; upregulation of CD4-positive, alpha beta T cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
CD4-positive, alpha-beta T cell lineage commitment (GO:0043373)
Namespace: biological_process
Definition: The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.
Synonyms: CD4-positive, alpha-beta T lymphocyte lineage commitment; CD4-positive, alpha-beta T-cell lineage commitment; CD4-positive, alpha-beta T-lymphocyte lineage commitment
CD8-positive, alpha-beta T cell differentiation (GO:0043374)
Namespace: biological_process
Definition: The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
Synonyms: CD8-positive, alpha-beta T cell development; CD8-positive, alpha-beta T lymphocyte differentiation; CD8-positive, alpha-beta T-cell differentiation; CD8-positive, alpha-beta T-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
CD8-positive, alpha-beta T cell lineage commitment (GO:0043375)
Namespace: biological_process
Definition: The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.
Synonyms: CD8-positive, alpha-beta T cell fate commitment; CD8-positive, alpha-beta T lymphocyte lineage commitment; CD8-positive, alpha-beta T-cell lineage commitment; CD8-positive, alpha-beta T-lymphocyte lineage commitment
regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043376)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.
Synonyms: regulation of CD8-positive T lymphocyte differentiation; regulation of CD8-positive T-cell differentiation; regulation of CD8-positive T-lymphocyte differentiation; regulation of CD8-positive, alpha beta T lymphocyte differentiation; regulation of CD8-positive, alpha beta T-cell differentiation; regulation of CD8-positive, alpha beta T-lymphocyte differentiation; regulation of CD8-positive, alpha-beta T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043377)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
Synonyms: down regulation of CD8-positive, alpha-beta T cell differentiation; down-regulation of CD8-positive, alpha-beta T cell differentiation; downregulation of CD8-positive, alpha-beta T cell differentiation; inhibition of CD8-positive, alpha-beta T cell differentiation; negative regulation of CD8-positive T lymphocyte differentiation; negative regulation of CD8-positive T-cell differentiation; negative regulation of CD8-positive T-lymphocyte differentiation; negative regulation of CD8-positive, alpha beta T lymphocyte differentiation; negative regulation of CD8-positive, alpha beta T-cell differentiation; negative regulation of CD8-positive, alpha beta T-lymphocyte differentiation; negative regulation of CD8-positive, alpha-beta T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043378)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.
Synonyms: activation of CD8-positive, alpha-beta T cell differentiation; positive regulation of CD8-positive T lymphocyte differentiation; positive regulation of CD8-positive T-cell differentiation; positive regulation of CD8-positive T-lymphocyte differentiation; positive regulation of CD8-positive, alpha beta T lymphocyte differentiation; positive regulation of CD8-positive, alpha beta T-cell differentiation; positive regulation of CD8-positive, alpha beta T-lymphocyte differentiation; positive regulation of CD8-positive, alpha-beta T cell development; stimulation of CD8-positive, alpha-beta T cell differentiation; up regulation of CD8-positive, alpha-beta T cell differentiation; up-regulation of CD8-positive, alpha-beta T cell differentiation; upregulation of CD8-positive, alpha-beta T cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
regulation of memory T cell differentiation (GO:0043380)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
Synonyms: regulation of memory T cell development; regulation of memory T lymphocyte differentiation; regulation of memory T-cell differentiation; regulation of memory T-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative regulation of memory T cell differentiation (GO:0043381)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate of memory T cell differentiation.
Synonyms: down regulation of memory T cell differentiation; down-regulation of memory T cell differentiation; downregulation of memory T cell differentiation; inhibition of memory T cell differentiation; negative regulation of memory T cell development; negative regulation of memory T lymphocyte differentiation; negative regulation of memory T-cell differentiation; negative regulation of memory T-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of memory T cell differentiation (GO:0043382)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.
Synonyms: activation of memory T cell differentiation; positive regulation of memory T cell development; positive regulation of memory T lymphocyte differentiation; positive regulation of memory T-cell differentiation; positive regulation of memory T-lymphocyte differentiation; stimulation of memory T cell differentiation; up regulation of memory T cell differentiation; up-regulation of memory T cell differentiation; upregulation of memory T cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative T cell selection (GO:0043383)
Namespace: biological_process
Definition: The process of elimination of immature T cells which react strongly with self-antigens.
Synonyms: negative T lymphocyte selection; negative T-cell selection; negative T-lymphocyte selection
pre-T cell receptor complex (GO:0043384)
Namespace: cellular_component
Definition: A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.
Synonyms: pre-T lymphocyte receptor complex; pre-T-cell receptor complex; pre-T-lymphocyte receptor complex; pre-TCR complex
mycotoxin metabolic process (GO:0043385)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
Synonyms: mycotoxin metabolism
mycotoxin biosynthetic process (GO:0043386)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
Synonyms: mycotoxin anabolism; mycotoxin biosynthesis; mycotoxin formation; mycotoxin synthesis
mycotoxin catabolic process (GO:0043387)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.
Synonyms: mycotoxin breakdown; mycotoxin catabolism; mycotoxin degradation
positive regulation of DNA binding (GO:0043388)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
Synonyms: activation of DNA binding; stimulation of DNA binding; up regulation of DNA binding; up-regulation of DNA binding; upregulation of DNA binding
negative regulation of DNA binding (GO:0043392)
Namespace: biological_process
Definition: Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
Synonyms: down regulation of DNA binding; down-regulation of DNA binding; downregulation of DNA binding; inhibition of DNA binding
regulation of protein binding (GO:0043393)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein binding.
proteoglycan binding (GO:0043394)
Namespace: molecular_function
Definition: Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
heparan sulfate proteoglycan binding (GO:0043395)
Namespace: molecular_function
Definition: Binding to a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
Synonyms: heparin proteoglycan binding
corticotropin-releasing hormone secretion (GO:0043396)
Namespace: biological_process
Definition: The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.
Synonyms: corticotropin-releasing factor secretion; CRF secretion; CRH secretion
regulation of corticotropin-releasing hormone secretion (GO:0043397)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.
Synonyms: regulation of corticotropin-releasing factor secretion; regulation of CRF secretion; regulation of CRH secretion
HLH domain binding (GO:0043398)
Namespace: molecular_function
Definition: Binding to a Helix Loop Helix domain, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.
tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity (GO:0043399)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.
Synonyms: initiator tRNA phosphoribosyl-transferase activity; tRNA A64-2'-O-ribosylphosphate transferase activity
steroid hormone receptor signaling pathway (GO:0043401)
Namespace: biological_process
Definition: The series of molecular signals mediated by a steroid hormone binding to a receptor.
Synonyms: steroid hormone mediated signalling; steroid hormone-mediated signaling pathway
obsolete glucocorticoid mediated signaling pathway (GO:0043402)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals mediated by the detection of a glucocorticoid hormone.
Synonyms: glucocorticoid mediated signalling
Comment: This term was obsoleted because it represents the same process as nuclear receptor-mediated glucocorticoid signaling pathway ; GO:0042921.
skeletal muscle tissue regeneration (GO:0043403)
Namespace: biological_process
Definition: The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
Synonyms: myofiber turnover
corticotropin-releasing hormone receptor activity (GO:0043404)
Namespace: molecular_function
Definition: Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.
Synonyms: adrenocorticotropin-releasing hormone receptor activity; corticotropin-releasing factor receptor activity; CRF receptor activity; CRH receptor activity
regulation of MAP kinase activity (GO:0043405)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of MAP kinase activity.
Synonyms: Regulation of MAPK activity; regulation of mitogen activated protein kinase activity; regulation of mitogen-activated protein kinase activity
positive regulation of MAP kinase activity (GO:0043406)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
Synonyms: positive regulation of mitogen activated protein kinase activity; positive regulation of mitogen-activated protein kinase activity; stimulation of MAPK activity; up regulation of MAPK activity; up-regulation of MAPK activity; upregulation of MAPK activity
negative regulation of MAP kinase activity (GO:0043407)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
Synonyms: down regulation of MAPK activity; down-regulation of MAPK activity; downregulation of MAPK activity; inhibition of MAPK activity; negative regulation of mitogen activated protein kinase activity; negative regulation of mitogen-activated protein kinase activity
regulation of MAPK cascade (GO:0043408)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
Synonyms: regulation of MAP kinase cascade; regulation of MAP kinase kinase kinase cascade; regulation of MAPKKK cascade; regulation of mitogen activated protein kinase cascade; regulation of mitogen activated protein kinase kinase kinase cascade; regulation of mitogen-activated protein kinase cascade; regulation of mitogen-activated protein kinase kinase kinase cascade
positive regulation of MAPK cascade (GO:0043410)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
Synonyms: activation of MAPK cascade; activation of MAPKKK cascade; positive regulation of MAP kinase cascade; positive regulation of MAP kinase kinase kinase cascade; positive regulation of MAPKKK cascade; positive regulation of mitogen activated protein kinase kinase kinase cascade; positive regulation of mitogen-activated protein kinase cascade; positive regulation of mitogen-activated protein kinase kinase kinase cascade; stimulation of MAPK cascade; stimulation of MAPKKK cascade; up regulation of MAPKKK cascade; up-regulation of MAPK cascade; up-regulation of MAPKKK cascade; upregulation of MAPK cascade; upregulation of MAPKKK cascade
obsolete myopalladin binding (GO:0043411)
Namespace: molecular_function
Definition: OBSOLETE. Binding to myopalladin, a myofibrillar protein with titin-like Ig domains.
Synonyms: myopalladin binding
Comment: This term was made obsolete because it represents binding to an individual protein.
macromolecule methylation (GO:0043414)
Namespace: biological_process
Definition: The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
positive regulation of skeletal muscle tissue regeneration (GO:0043415)
Namespace: biological_process
Definition: Any process that activates or increase the rate of skeletal muscle regeneration.
Synonyms: activation of skeletal muscle regeneration; stimulation of skeletal muscle regeneration; up regulation of skeletal muscle regeneration; up-regulation of skeletal muscle regeneration; upregulation of skeletal muscle regeneration
regulation of skeletal muscle tissue regeneration (GO:0043416)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of skeletal muscle.
negative regulation of skeletal muscle tissue regeneration (GO:0043417)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.
Synonyms: down regulation of skeletal muscle regeneration; down-regulation of skeletal muscle regeneration; downregulation of skeletal muscle regeneration; inhibition of skeletal muscle regeneration
L-homocysteine catabolic process (GO:0043418)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.
Synonyms: homocysteine breakdown; homocysteine catabolism; homocysteine degradation
urea catabolic process (GO:0043419)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
Synonyms: urea breakdown; urea catabolism; urea decomposition; urea degradation
obsolete anthranilate metabolic process (GO:0043420)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
Synonyms: 2-aminobenzoate metabolic process; 2-aminobenzoate metabolism; anthranilate catabolic process; anthranilate metabolism; anthranilic acid metabolic process; anthranilic acid metabolism; ortho-aminobenzoic acid metabolic process; ortho-aminobenzoic acid metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
anthranilate catabolic process (GO:0043421)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).
Synonyms: 2-aminobenzoate breakdown; 2-aminobenzoate catabolic process; 2-aminobenzoate catabolism; 2-aminobenzoate degradation; anthranilate breakdown; anthranilate catabolism; anthranilate degradation; anthranilic acid catabolic process; anthranilic acid catabolism; ortho-aminobenzoic acid catabolic process; ortho-aminobenzoic acid catabolism
protein kinase B binding (GO:0043422)
Namespace: molecular_function
Definition: Binding to protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
Synonyms: Akt binding; PKB binding
3-phosphoinositide-dependent protein kinase binding (GO:0043423)
Namespace: molecular_function
Definition: Binding to a 3-phosphoinositide-dependent protein kinase.
Synonyms: phosphatidylinositol-3-phosphate-dependent protein kinase binding
protein histidine kinase binding (GO:0043424)
Namespace: molecular_function
Definition: Binding to a protein histidine kinase.
Synonyms: histidine kinase binding; histidine-protein kinase binding; protein-histidine kinase binding
bHLH transcription factor binding (GO:0043425)
Namespace: molecular_function
Definition: Binding to a basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
MRF binding (GO:0043426)
Namespace: molecular_function
Definition: Binding to Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
Synonyms: Mrf4 binding; Myf5 binding; MyoD binding; myogenin binding
carbon fixation by 3-hydroxypropionate cycle (GO:0043427)
Namespace: biological_process
Definition: An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.
Synonyms: 3-hydroxypropionate cycle; 3-hydroxypropionate pathway; hydroxypropionate cycle; hydroxypropionate pathway
obsolete 2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity (GO:0043428)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
Synonyms: 2-heptaprenyl-6-methoxy-1,4-benzoquinone methylase activity
Comment: This term was obsoleted because it represents a specific substrate.
obsolete 2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity (GO:0043429)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
Synonyms: 2-nonaprenyl-6-methoxy-1,4-benzoquinone methylase activity
Comment: This term was obsoleted because it represents a specific substrate.
obsolete 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity (GO:0043430)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
Synonyms: 2-decaprenyl-6-methoxy-1,4-benzoquinone methylase activity
Comment: This term was obsoleted because it represents a specific substrate.
obsolete 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity (GO:0043431)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine.
Synonyms: 2-octaprenyl-6-hydroxy phenol methylase activity; 3-demethylubiquinone-9 3-methyltransferase activity
Comment: This term was obsoleted because it represents a specific substrate of 3-demethylubiquinol-n 3-O-methyltransferase activity ; GO:0061542.