LiteFold/GO huggingface dataset:
dsRNA transport (GO:0033227)
Namespace: biological_process
Definition: The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
cysteine export across plasma membrane (GO:0033228)
Namespace: biological_process
Definition: The directed movement of cysteine from inside of a cell, across the plasma membrane and into the extracellular region.
Synonyms: cysteine export
cysteine transmembrane transporter activity (GO:0033229)
Namespace: molecular_function
Definition: Enables the transfer of cysteine from one side of a membrane to the other.
ABC-type cysteine transporter activity (GO:0033230)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-cysteine(in) = ADP + H+ + L-cysteine(out) + phosphate.
Synonyms: ATP-dependent cysteine transporter activity; ATPase-coupled cysteine transmembrane transporter activity; ATPase-coupled cysteine transporter activity; cysteine exporter; cysteine-exporting ATPase activity; cysteine-transporting ATPase activity
ABC-type D-methionine transporter activity (GO:0033232)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).
Synonyms: ATP-dependent D-methionine transporter activity; ATP-dependent methionine transmembrane transporter activity; ATPase-coupled D-methionine transporter activity; ATPase-coupled methionine transmembrane transporter activity; D-methionine exporter; D-methionine importer; D-methionine transmembrane transporter activity; D-methionine transporter activity; D-methionine-exporting ATPase activity; D-methionine-importing ATPase activity; D-methionine-transporting ATPase activity; methionine transmembrane-transporting ATPase activity
regulation of protein sumoylation (GO:0033233)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.
Synonyms: regulation of sumoylation
negative regulation of protein sumoylation (GO:0033234)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
Synonyms: negative regulation of sumoylation
positive regulation of protein sumoylation (GO:0033235)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
Synonyms: positive regulation of sumoylation
obsolete 11-beta-hydroxysteroid dehydrogenase (NAD+) activity (GO:0033236)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.
Synonyms: 11-beta-hydroxysteroid dehydrogenase (NAD+) activity
obsolete 11-beta-hydroxysteroid dehydrogenase (NADP+) activity (GO:0033237)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.
Synonyms: 11-beta-hydroxysteroid dehydrogenase (NADP+) activity; 11beta-hydroxysteroid:NADP+ 11-oxidoreductase; beta-hydroxysteroid dehydrogenase; corticosteroid 11-beta-dehydrogenase activity
regulation of amine metabolic process (GO:0033238)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.
Synonyms: regulation of amine metabolism; regulation of cellular amine metabolic process
negative regulation of amine metabolic process (GO:0033239)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.
Synonyms: negative regulation of amine metabolism; negative regulation of cellular amine metabolic process
regulation of amine catabolic process (GO:0033241)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
Synonyms: regulation of amine breakdown; regulation of amine catabolism; regulation of amine degradation; regulation of cellular amine catabolic process
negative regulation of amine catabolic process (GO:0033242)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
Synonyms: negative regulation of amine breakdown; negative regulation of amine catabolism; negative regulation of amine degradation; negative regulation of cellular amine catabolic process
positive regulation of amine catabolic process (GO:0033243)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
Synonyms: positive regulation of amine breakdown; positive regulation of amine catabolism; positive regulation of amine degradation
obsolete regulation of penicillin metabolic process (GO:0033244)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: regulation of penicillin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete negative regulation of penicillin metabolic process (GO:0033245)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: negative regulation of penicillin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
positive regulation of penicillin metabolic process (GO:0033246)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: positive regulation of penicillin metabolism
regulation of penicillin catabolic process (GO:0033247)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: regulation of penicillin breakdown; regulation of penicillin catabolism; regulation of penicillin degradation
negative regulation of penicillin catabolic process (GO:0033248)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: negative regulation of penicillin breakdown; negative regulation of penicillin catabolism; negative regulation of penicillin degradation
positive regulation of penicillin catabolic process (GO:0033249)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
Synonyms: positive regulation of penicillin breakdown; positive regulation of penicillin catabolism; positive regulation of penicillin degradation
obsolete penicillinase activity (GO:0033250)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.
Comment: This term was obsoleted because it represents a specific substrate of beta-lactamase activity ; GO:0008800.
obsolete cephalosporinase activity (GO:0033251)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.
Comment: This term was obsoleted because it represents a specific substrate of beta-lactamase activity ; GO:0008800.
regulation of beta-lactamase activity (GO:0033252)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.
obsolete regulation of penicillinase activity (GO:0033253)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.
Comment: This term was obsoleted because it represents a molecular function.
vacuolar transporter chaperone complex (GO:0033254)
Namespace: cellular_component
Definition: A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.
Synonyms: VTC complex
SAS acetyltransferase complex (GO:0033255)
Namespace: cellular_component
Definition: A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.
Synonyms: SAS-I complex
I-kappaB/NF-kappaB complex (GO:0033256)
Namespace: cellular_component
Definition: A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.
Bcl3/NF-kappaB2 complex (GO:0033257)
Namespace: cellular_component
Definition: A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.
Synonyms: Bcl3-NFKB2 complex; Bcl3-p52 complex
plastid DNA metabolic process (GO:0033258)
Namespace: biological_process
Definition: The chemical reactions and pathways involving plastid DNA.
Synonyms: plastid DNA metabolism
plastid DNA replication (GO:0033259)
Namespace: biological_process
Definition: The process in which new strands of DNA are synthesized in a plastid.
Synonyms: plastid DNA synthesis; replication of plastid DNA
obsolete regulation of S phase (GO:0033261)
Namespace: biological_process
Definition: OBSOLETE. A cell cycle process that modulates the rate or extent of the progression through the S phase of the cell cycle.
Synonyms: regulation of progression through S phase; regulation of S phase; regulation of S-phase
Comment: This term was made obsolete because cell cycle phases are intervals and so cannot be regulated as such, rather it is the transitions between the phases that are regulated. This term was often also used to annotate genes which should have been annotated to 'regulation of DNA replication', or one of its children.
regulation of nuclear cell cycle DNA replication (GO:0033262)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
Synonyms: regulation of DNA replication during S phase; regulation of DNA replication involved in S phase; regulation of DNA replication involved in S-phase
obsolete bontoxilysin activity (GO:0033264)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
Synonyms: BoNT; bontoxilysin activity; botulinum neurotoxin activity
Comment: This term was made obsolete because it represents a gene product.
choline binding (GO:0033265)
Namespace: molecular_function
Definition: Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.
ABC-type choline transporter activity (GO:0033266)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
Synonyms: ABC-type choline transmembrane transporter activity; ATP-dependent choline transmembrane transporter activity; ATPase-coupled choline transmembrane transporter activity; choline-transporting ATPase activity
node of Ranvier (GO:0033268)
Namespace: cellular_component
Definition: An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.
Synonyms: node of Ranvier axon
internode region of axon (GO:0033269)
Namespace: cellular_component
Definition: An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.
Synonyms: internode
myo-inositol phosphate transport (GO:0033271)
Namespace: biological_process
Definition: The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
myo-inositol hexakisphosphate transport (GO:0033272)
Namespace: biological_process
Definition: The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: phytate transport
response to vitamin (GO:0033273)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
response to vitamin B2 (GO:0033274)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
Synonyms: response to riboflavin
actin-myosin filament sliding (GO:0033275)
Namespace: biological_process
Definition: The sliding movement of actin thin filaments and myosin thick filaments past each other.
Synonyms: actin filament sliding
transcription factor TFTC complex (GO:0033276)
Namespace: cellular_component
Definition: A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.
obsolete abortive mitotic cell cycle (GO:0033277)
Namespace: biological_process
Definition: OBSOLETE. A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.
Synonyms: abortive mitosis
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
cell proliferation in midbrain (GO:0033278)
Namespace: biological_process
Definition: The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.
Synonyms: cell proliferation in mesencephalon; mesencepahalic cell proliferation
response to vitamin D (GO:0033280)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
Synonyms: response to calciferol; response to cholecalciferol; response to ergocalciferol
protein C inhibitor-acrosin complex (GO:0033282)
Namespace: cellular_component
Definition: A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.
Synonyms: PCI-ACR complex; PCI-acrosin complex; plasma serine protease inhibitor-acrosin complex; serpin A5-acrosin complex; SERPINA5-acrosin complex
obsolete ATPase-coupled organic acid transmembrane transporter activity (GO:0033283)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of an organic acid from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).
Synonyms: ATP-dependent organic acid transmembrane transporter activity; organic acid-transporting ATPase activity
Comment: The reason for obsoletion is that this term was an unnecessary and confusing grouping term.
ATPase-coupled carboxylic acid transmembrane transporter activity (GO:0033284)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).
Synonyms: ATP-dependent carboxylic acid transporter activity; carboxylic acid-transporting ATPase activity
ATPase-coupled monocarboxylic acid transmembrane transporter activity (GO:0033285)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).
Synonyms: ATP-dependent monocarboxylic acid transmembrane transporter activity; monocarboxylic acid-transporting ATPase activity
ATPase-coupled ectoine transmembrane transporter activity (GO:0033286)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).
Synonyms: ATP-dependent ectoine transmembrane transporter activity; ectoine transmembrane transporter activity; ectoine-transporting ATPase activity
ATPase-coupled hydroxyectoine transmembrane transporter activity (GO:0033288)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).
Synonyms: ATP-dependent hydroxyectoine transmembrane transporter activity; hydroxyectoine transmembrane transporter activity; hydroxyectoine-transporting ATPase activity
eukaryotic 48S preinitiation complex (GO:0033290)
Namespace: cellular_component
Definition: The protein-ribosome-tRNA complex that has just recognized the start codon of a capped mRNA. It is composed of the small ribosomal subunit, eukaryote initiation factors (eIF) eIF3 complex, eIF1, eIF1A, eIF2-GDP, eIF4 complex and initiatior-methionine-tRNA. Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC.
Synonyms: eukaryotic 48S initiation complex; eukaryotic 48S pre-initiation complex
eukaryotic 80S initiation complex (GO:0033291)
Namespace: cellular_component
Definition: A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.
T-tubule organization (GO:0033292)
Namespace: biological_process
Definition: A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
Synonyms: T-tubule organisation; T-tubule organization and biogenesis; transverse tubule organization
monocarboxylic acid binding (GO:0033293)
Namespace: molecular_function
Definition: Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).
hydroxyectoine binding (GO:0033295)
Namespace: molecular_function
Definition: Binding to hydroxyectoine.
rhamnose binding (GO:0033296)
Namespace: molecular_function
Definition: Binding to the D- or L-enantiomer of rhamnose.
contractile vacuole organization (GO:0033298)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.
Synonyms: contractile vacuole organisation; contractile vacuole organization and biogenesis
secretion of lysosomal enzymes (GO:0033299)
Namespace: biological_process
Definition: The controlled release of lysosomal enzymes by a cell.
cell cycle comprising mitosis without cytokinesis (GO:0033301)
Namespace: biological_process
Definition: A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).
Comment: Note that this term should be used for naturally occurring instances of mitosis without cytokinesis, e.g. in the tapetum of flowers and in a number of lower eukaryotes; it should not be used for abnormal events such as may occur in cancers.
obsolete quercetin O-glucoside metabolic process (GO:0033302)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.
Synonyms: quercetin O-glucoside metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
quercetin O-glucoside biosynthetic process (GO:0033303)
Namespace: biological_process
Definition: The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.
Synonyms: quercetin O-glucoside anabolism; quercetin O-glucoside biosynthesis; quercetin O-glucoside formation; quercetin O-glucoside synthesit
obsolete chlorophyll a metabolic process (GO:0033304)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving chlorophyll a.
Synonyms: chlorophyll a metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
chlorophyll a biosynthetic process (GO:0033305)
Namespace: biological_process
Definition: The chemical reactions and pathways leading to the formation of chlorophyll a.
Synonyms: chlorophyll a anabolism; chlorophyll a biosynthesis; chlorophyll a formation; chlorophyll a synthesis
phytol metabolic process (GO:0033306)
Namespace: biological_process
Definition: The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
Synonyms: phytol metabolism
hydroxyectoine transmembrane transport (GO:0033308)
Namespace: biological_process
Definition: The directed movement of hydroxyectoine across a membrane by means of some agent such as a transporter or a pore.
Synonyms: hydroxyectoine transport