LiteFold/GO huggingface dataset:
obsolete axonemal dynein heavy chain (GO:0001683)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: axonemal dynein heavy chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete axonemal dynein intermediate chain (GO:0001684)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: axonemal dynein intermediate chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete axonemal dynein intermediate light chain (GO:0001685)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: axonemal dynein intermediate light chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete axonemal dynein light chain (GO:0001686)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: axonemal dynein light chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete cytoplasmic dynein heavy chain (GO:0001687)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytoplasmic dynein heavy chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete cytoplasmic dynein intermediate chain (GO:0001688)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytoplasmic dynein intermediate chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete cytoplasmic dynein intermediate light chain (GO:0001689)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytoplasmic dynein intermediate light chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete cytoplasmic dynein light chain (GO:0001690)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytoplasmic dynein light chain
Comment: This term was made obsolete because it represents a single gene product and not a complex.
pseudophosphatase activity (GO:0001691)
Namespace: molecular_function
Definition: Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
histamine metabolic process (GO:0001692)
Namespace: biological_process
Definition: The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
Synonyms: histamine metabolism
histamine biosynthetic process (GO:0001694)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
Synonyms: histamine anabolism; histamine biosynthesis; histamine formation; histamine synthesis
histamine catabolic process (GO:0001695)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
Synonyms: histamine breakdown; histamine catabolism; histamine degradation
gastric acid secretion (GO:0001696)
Namespace: biological_process
Definition: The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
Synonyms: hydrochloric acid secretion
histamine-induced gastric acid secretion (GO:0001697)
Namespace: biological_process
Definition: The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.
gastrin-induced gastric acid secretion (GO:0001698)
Namespace: biological_process
Definition: The regulated release of gastric acid induced by the interaction of gastrin with its receptor.
acetylcholine-induced gastric acid secretion (GO:0001699)
Namespace: biological_process
Definition: The regulated release of gastric acid by parietal cells in response to acetylcholine.
embryonic development via the syncytial blastoderm (GO:0001700)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
in utero embryonic development (GO:0001701)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
gastrulation with mouth forming second (GO:0001702)
Namespace: biological_process
Definition: A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.
Synonyms: deuterostomic gastrulation
gastrulation with mouth forming first (GO:0001703)
Namespace: biological_process
Definition: A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.
Synonyms: protostomic gastrulation
ectoderm formation (GO:0001705)
Namespace: biological_process
Definition: The formation of ectoderm during gastrulation.
endoderm formation (GO:0001706)
Namespace: biological_process
Definition: The formation of the endoderm during gastrulation.
Synonyms: endoblast formation
mesoderm formation (GO:0001707)
Namespace: biological_process
Definition: The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
cell fate specification (GO:0001708)
Namespace: biological_process
Definition: The cellular developmental process involved in cell fate commitment in which the cell is designated to follow a developmental path, unless they receive extrinsic cues that direct an alternative fate.
mesodermal cell fate commitment (GO:0001710)
Namespace: biological_process
Definition: The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
Synonyms: mesoderm cell fate commitment
ectodermal cell fate commitment (GO:0001712)
Namespace: biological_process
Definition: The cell differentiation process that results in commitment of a cell to become part of the ectoderm.
Synonyms: ectoderm cell fate commitment
ectodermal cell fate determination (GO:0001713)
Namespace: biological_process
Definition: The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Synonyms: ectoderm cell fate determination
endodermal cell fate specification (GO:0001714)
Namespace: biological_process
Definition: The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms: endoderm cell fate specification
ectodermal cell fate specification (GO:0001715)
Namespace: biological_process
Definition: The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Synonyms: ectoderm cell fate specification
L-amino-acid oxidase activity (GO:0001716)
Namespace: molecular_function
Definition: Catalysis of the reaction: an L-alpha-amino acid + H2O + O2 = a 2-oxocarboxylate + H2O2 + NH4+.
Synonyms: L-amino-acid:oxygen oxidoreductase (deaminating); ophio-amino-acid oxidase activity
conversion of seryl-tRNAsec to selenocys-tRNAsec (GO:0001717)
Namespace: biological_process
Definition: The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.
conversion of lysyl-tRNA to pyrrolysyl-tRNA (GO:0001720)
Namespace: biological_process
Definition: The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).
obsolete intermediate filament associated protein (GO:0001721)
Namespace: cellular_component
Definition: OBSOLETE. Proteins that associate with intermediate filaments and function in the supramolecular organization of cellular intermediate filament networks.
Synonyms: IFAP; intermediate filament associated protein
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete type I intermediate filament associated protein (GO:0001722)
Namespace: cellular_component
Definition: OBSOLETE. Low molecular weight (10-45 kDa) proteins that associate with intermediate filaments by lateral binding of the filaments and have the effect of creating tight macrofilament aggregates.
Synonyms: type I intermediate filament associated protein
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete type II intermediate filament associated protein (GO:0001723)
Namespace: cellular_component
Definition: OBSOLETE. High molecular weight (100-300 kDa) proteins that associate with intermediate filaments to cross-link them into loose networks.
Synonyms: type II intermediate filament associated protein
Comment: This term was made obsolete because it represents a single gene product and not a complex.
obsolete type III intermediate filament associated protein (GO:0001724)
Namespace: cellular_component
Definition: OBSOLETE. Proteins that associate with the ends of intermediate filaments and couple the intermediate filaments to the plasma membrane.
Synonyms: type III intermediate filament associated protein
Comment: This term was made obsolete because it represents a single gene product and not a complex.
stress fiber (GO:0001725)
Namespace: cellular_component
Definition: A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
Synonyms: actin cable; stress fibre
ceramide kinase activity (GO:0001729)
Namespace: molecular_function
Definition: Catalysis of the reaction: an N-acylsphing-4-enine + ATP = ADP + an N-acylsphing-4-enine 1-phosphate + H+.
Synonyms: acylsphingosine kinase activity; ATP:ceramide 1-phosphotransferase activity
2'-5'-oligoadenylate synthetase activity (GO:0001730)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.
Synonyms: (2-5')oligo(A) synthetase activity; 2'-5' oligoadenylate synthetase activity; 2-5A synthetase activity; oligo-2',5'-adenylate synthetase activity
formation of translation preinitiation complex (GO:0001731)
Namespace: biological_process
Definition: The joining of the small ribosomal subunit, ternary complex, and mRNA.
Synonyms: formation of translation pre-initiation complex; translation preinitiation complex assembly
Comment: See also the cellular component terms 'eukaryotic 43S preinitiation complex ; GO:0016282', 'eukaryotic 48S initiation complex ; GO:0033290', and their children.
formation of cytoplasmic translation initiation complex (GO:0001732)
Namespace: biological_process
Definition: Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
Synonyms: cytoplasmic translation initiation complex assembly; formation of translation initiation complex; translation initiation complex assembly
galactosylceramide sulfotransferase activity (GO:0001733)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.
Synonyms: 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase activity; 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase activity; cerebroside sulfotransferase activity; galactocerebroside sulfotransferase activity; galactolipid sulfotransferase activity; galactosylceramide sulphotransferase activity; glycolipid sulfotransferase activity; glycosphingolipid sulfotransferase activity; GSase
mRNA m(6)A methyltransferase activity (GO:0001734)
Namespace: molecular_function
Definition: Catalysis of the reaction: an adenosine in mRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in mRNA + H+ + S-adenosyl-L-homocysteine. This activity is the methylation of adenines in mRNA with the consensus sequence RRACH, where R is a purine, and H is C, A, or U.
Synonyms: mRNA (N6-adenosine)-methyltransferase activity
prenylcysteine oxidase activity (GO:0001735)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.
Synonyms: prenylcysteine lyase activity; S-prenyl-L-cysteine:oxygen oxidoreductase activity
establishment of planar polarity (GO:0001736)
Namespace: biological_process
Definition: Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
Synonyms: establishment of planar cell polarity
establishment of imaginal disc-derived wing hair orientation (GO:0001737)
Namespace: biological_process
Definition: Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
Synonyms: establishment of wing hair orientation
morphogenesis of a polarized epithelium (GO:0001738)
Namespace: biological_process
Definition: The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
Synonyms: epithelial polarization
sex chromatin (GO:0001739)
Namespace: cellular_component
Definition: Chromatin that is part of a sex chromosome.
Barr body (GO:0001740)
Namespace: cellular_component
Definition: A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
XY body (GO:0001741)
Namespace: cellular_component
Definition: A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
oenocyte differentiation (GO:0001742)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
Synonyms: oenocyte cell differentiation
lens placode formation (GO:0001743)
Namespace: biological_process
Definition: The initial developmental process that will lead to the formation of an eye.
Synonyms: optic placode formation
insect visual primordium formation (GO:0001744)
Namespace: biological_process
Definition: Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.
Synonyms: optic lobe and Bolwig's organ precursor formation; optic lobe placode formation
compound eye morphogenesis (GO:0001745)
Namespace: biological_process
Definition: The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
Synonyms: insect-type retina morphogenesis
Bolwig's organ morphogenesis (GO:0001746)
Namespace: biological_process
Definition: The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
insect visual primordium development (GO:0001748)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.
Synonyms: optic lobe and Bolwig's organ precursor development; optic lobe placode development; optic placode development
photoreceptor outer segment (GO:0001750)
Namespace: cellular_component
Definition: The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
compound eye photoreceptor cell differentiation (GO:0001751)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
compound eye photoreceptor fate commitment (GO:0001752)
Namespace: biological_process
Definition: The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
obsolete adult eye photoreceptor development (sensu Drosophila) (GO:0001753)
Namespace: biological_process
Definition: OBSOLETE. Development of a photoreceptor, a receptor that responds to light, in the adult Drosophila eye.
Synonyms: adult eye photoreceptor development (sensu Drosophila)
Comment: This term was made obsolete because eye photoreceptors have completed their development by the time the adult phase begins.
eye photoreceptor cell differentiation (GO:0001754)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
neural crest cell migration (GO:0001755)
Namespace: biological_process
Definition: The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
somitogenesis (GO:0001756)
Namespace: biological_process
Definition: The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
Synonyms: formation of mesodermal clusters
somite specification (GO:0001757)
Namespace: biological_process
Definition: The process in which individual somites establish identity during embryogenesis.
retinal dehydrogenase (NAD+) activity (GO:0001758)
Namespace: molecular_function
Definition: Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
Synonyms: cytosolic retinal dehydrogenase activity; retinal dehydrogenase activity; retinal:NAD+ oxidoreductase activity
organ induction (GO:0001759)
Namespace: biological_process
Definition: The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.
Synonyms: induction of an organ
aminocarboxymuconate-semialdehyde decarboxylase activity (GO:0001760)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H+ = 2-aminomuconate 6-semialdehyde + CO2.
Synonyms: 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming); 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase activity; 2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase activity; ACMSD activity; alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase activity; alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase activity; picolinic acid carboxylase activity; picolinic acid decarboxylase activity
beta-alanine transmembrane transporter activity (GO:0001761)
Namespace: molecular_function
Definition: Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
Synonyms: beta-alanine transporter activity
beta-alanine transport (GO:0001762)
Namespace: biological_process
Definition: The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
morphogenesis of a branching structure (GO:0001763)
Namespace: biological_process
Definition: The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.
Synonyms: branching morphogenesis
neuron migration (GO:0001764)
Namespace: biological_process
Definition: The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
Synonyms: neuron chemotaxis; neuron guidance; neuronal migration
membrane raft assembly (GO:0001765)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
Synonyms: lipid raft assembly; lipid raft formation; membrane raft formation
membrane raft polarization (GO:0001766)
Namespace: biological_process
Definition: The clustering and aggregation of a membrane into domains. This serves as a mechanism to compartmentalize cellular activities and to establish cell polarity.
Synonyms: lipid raft polarization; membrane polarization
establishment of lymphocyte polarity (GO:0001767)
Namespace: biological_process
Definition: The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
Synonyms: lymphocyte polarization
establishment of T cell polarity (GO:0001768)
Namespace: biological_process
Definition: The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
Synonyms: establishment of T lymphocyte polarity; establishment of T-cell polarity; establishment of T-lymphocyte polarity; T cell polarization; T lymphocyte polarization; T-cell polarization