LiteFold/GO huggingface dataset:
obsolete envenomation resulting in positive regulation of argininosuccinate synthase activity in another organism (GO:0099127)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism.
Synonyms: envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism
Comment: This term was obsoleted because it represents a molecular function.
mitochondrial [2Fe-2S] assembly complex (GO:0099128)
Namespace: cellular_component
Definition: A protein complex capable of forming 2Fe-2S clusters in mitochondria. In humans it consists of ISCU, NFS1, LYRM4, NDUFAB1 and FXN.
Synonyms: mitochondrial iron-sulfur cluster assembly complex; mitochondrial ISCU complex
cochlear outer hair cell electromotile response (GO:0099129)
Namespace: biological_process
Definition: A rapid, force generating length change of an outer hair cell in response to electrical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification.
estrogen binding (GO:0099130)
Namespace: molecular_function
Definition: Binding to an estrogen.
chimeric sorocarp development (GO:0099134)
Namespace: biological_process
Definition: Development of a sorocarp formed by aggregation of cells with different genotypes.
chimeric colonial development (GO:0099135)
Namespace: biological_process
Definition: Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.
chimeric non-reproductive fruiting body development (GO:0099136)
Namespace: biological_process
Definition: Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.
altruistic, chimeric, non-reproductive fruiting body development (GO:0099137)
Namespace: biological_process
Definition: Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.
Synonyms: fully co-operative, chimeric, non-reproductive fruiting body development
altruistic, chimeric sorocarp development (GO:0099138)
Namespace: biological_process
Definition: Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.
Synonyms: fully co-operative, chimeric sorocarp development
cheating during chimeric sorocarp development (GO:0099139)
Namespace: biological_process
Definition: Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.
presynaptic actin cytoskeleton organization (GO:0099140)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.
cellular response to protozoan (GO:0099141)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
intracellularly ATP-gated ion channel activity (GO:0099142)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts on the intracellular side of the plasma membrane.
presynaptic actin cytoskeleton (GO:0099143)
Namespace: cellular_component
Definition: The actin cytoskeleton that is part of a presynapse.
obsolete anchored component of synaptic membrane (GO:0099144)
Namespace: cellular_component
Definition: OBSOLETE. The component of the synaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane (GO:0099145)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane.
obsolete intrinsic component of postsynaptic density membrane (GO:0099146)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic density membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to postsynaptic specialization membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
extrinsic component of postsynaptic density membrane (GO:0099147)
Namespace: cellular_component
Definition: The component of the postsynaptic density membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
regulation of postsynaptic neurotransmitter receptor internalization (GO:0099149)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.
Synonyms: regulation of postsynaptic neurotransmitter receptor endocytosis
regulation of postsynaptic specialization assembly (GO:0099150)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.
regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0099152)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
synaptic transmission, serotonergic (GO:0099153)
Namespace: biological_process
Definition: The vesicular release of serotonin from a presynapse, across a chemical synapse, the subsequent activation of serotonin receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Synonyms: serotonergic synaptic transmission
serotonergic synapse (GO:0099154)
Namespace: cellular_component
Definition: A synapse that uses serotonin as a neurotransmitter.
synaptic transmission, noradrenergic (GO:0099155)
Namespace: biological_process
Definition: The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Synonyms: noradrenergic synaptic transmission
cell-cell signaling via exosome (GO:0099156)
Namespace: biological_process
Definition: Cell-cell signaling in which the ligand is carried between cells by an exosome.
Synonyms: exosome mediated
trans-synaptic signaling via exosome (GO:0099157)
Namespace: biological_process
Definition: Transynaptic signaling in which the ligand is carried across the synapse by an exosome.
Synonyms: exosome mediated transynaptic signalling; trans-synaptic signalling via exosome
regulation of recycling endosome localization within postsynapse (GO:0099158)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.
regulation of modification of postsynaptic structure (GO:0099159)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.
Synonyms: regulation of postsynapse remodelling
postsynaptic intermediate filament cytoskeleton (GO:0099160)
Namespace: cellular_component
Definition: The intermediate filament cytoskeleton that is part of a postsynapse.
regulation of presynaptic dense core granule exocytosis (GO:0099161)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.
Synonyms: regulation of presynaptic dense core vesicle exocytosis
regulation of neurotransmitter loading into synaptic vesicle (GO:0099162)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.
Synonyms: regulation of neurotransmitter uptake into synaptic vesicle; regulation of synaptic vesicle neurotransmitter loading
synaptic signaling by nitric oxide (GO:0099163)
Namespace: biological_process
Definition: Cell-cell signaling to or from a synapse, mediated by nitric oxide.
postsynaptic specialization membrane of symmetric synapse (GO:0099164)
Namespace: cellular_component
Definition: The membrane component of the postsynaptic specialization of a symmetric synapse. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
postsynaptic specialization of symmetric synapse, intracellular component (GO:0099165)
Namespace: cellular_component
Definition: A network of proteins adjacent to the postsynaptic membrane of a symmetric synapse. Its major components include that spatially and functionally organize neurotransmitter receptors in the adjacent membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components. This structure is not as thick or electron dense as the postsynaptic density found in asymmetric synapses.
obsolete intrinsic component of postsynaptic specialization membrane of symmetric synapse (GO:0099166)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to postsynaptic specialization membrane of symmetric synapse
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete integral component of postsynaptic specialization membrane of symmetric synapse (GO:0099167)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete extrinsic component of postsynaptic specialization membrane of symmetric synapse (GO:0099168)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic specialization membrane of a symmetric synapse consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete anchored component of postsynaptic specialization membrane of symmetric synapse (GO:0099169)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic specialization membrane of a symmetric synapse consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
postsynaptic modulation of chemical synaptic transmission (GO:0099170)
Namespace: biological_process
Definition: Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission.
presynaptic modulation of chemical synaptic transmission (GO:0099171)
Namespace: biological_process
Definition: Any process, acting in the presynapse that results in modulation of chemical synaptic transmission.
postsynapse organization (GO:0099173)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.
Synonyms: postsynapse development; postsynapse morphogenesis; postsynapse organisation; postsynapse organization and biogenesis
regulation of presynapse organization (GO:0099174)
Namespace: biological_process
Definition: Any process that modulates the physical form of a presynapse.
Synonyms: regulation of presynapse organisation; regulation of presynapse organization and biogenesis; regulation of presynapse structure
regulation of retrograde trans-synaptic signaling by trans-synaptic protein complex (GO:0099176)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by a trans-synaptic complex.
Synonyms: regulation of trans-synaptic complex mediated retrograde trans-synaptic signaling
regulation of trans-synaptic signaling (GO:0099177)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of trans-synaptic signaling.
regulation of retrograde trans-synaptic signaling by endocanabinoid (GO:0099178)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by an endocannabinoid.
Synonyms: regulation of endocannabinoid-mediated retrograde trans-synaptic signaling
regulation of synaptic membrane adhesion (GO:0099179)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.
Synonyms: regulation of synapse adhesion between pre- and post-synapse
zinc ion import into synaptic vesicle (GO:0099180)
Namespace: biological_process
Definition: The directed movement of Zn2+ ions from the cytoplasm into the lumen of a cytoplasmic vesicle.
Synonyms: zinc import into synaptic vesicle; Zn2+ import into synaptic vesicle
structural constituent of presynapse (GO:0099181)
Namespace: molecular_function
Definition: The action of a molecule that contributes to the structural integrity of a presynapse.
presynaptic intermediate filament cytoskeleton (GO:0099182)
Namespace: cellular_component
Definition: The intermediate filament cytoskeleton that is part of a presynapse.
trans-synaptic signaling by BDNF, modulating synaptic transmission (GO:0099183)
Namespace: biological_process
Definition: Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of brain derived neurotrophic factor (BDNF), that modulates the synaptic transmission properties of the synapse.
Comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
structural constituent of postsynaptic intermediate filament cytoskeleton (GO:0099184)
Namespace: molecular_function
Definition: The action of a molecule that contributes to the structural integrity of a postsynaptic intermediate filament cytoskeleton.
postsynaptic intermediate filament cytoskeleton organization (GO:0099185)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprised of intermediate filament and their associated proteins in the postsynaptic cytoskeleton.
structural constituent of postsynapse (GO:0099186)
Namespace: molecular_function
Definition: The action of a molecule that contributes to the structural integrity of a postsynapse.
presynaptic cytoskeleton organization (GO:0099187)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton.
postsynaptic cytoskeleton organization (GO:0099188)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton.
postsynaptic spectrin-associated cytoskeleton (GO:0099189)
Namespace: cellular_component
Definition: The portion of the spectrin-associated cytoskeleton contained within the postsynapse.
postsynaptic spectrin-associated cytoskeleton organization (GO:0099190)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of spectrin-associated cytoskeleton and associated proteins in the postsynapse.
trans-synaptic signaling by BDNF (GO:0099191)
Namespace: biological_process
Definition: Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.
Synonyms: trans-synaptic signaling by brain-derived neurotrophic factor
cerebellar Golgi cell to granule cell synapse (GO:0099192)
Namespace: cellular_component
Definition: A synapse formed by a cerebellar Golgi cell synapsing on to a cerebellar granule cell.
obsolete intrinsic component of synaptic membrane (GO:0099240)
Namespace: cellular_component
Definition: OBSOLETE. The component of the synaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to synaptic membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
extrinsic component of synaptic membrane (GO:0099243)
Namespace: cellular_component
Definition: The component of the synaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
caveola neck (GO:0099400)
Namespace: cellular_component
Definition: A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.
caveola bulb (GO:0099401)
Namespace: cellular_component
Definition: The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins.
Synonyms: caveola crater
plant organ development (GO:0099402)
Namespace: biological_process
Definition: Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
Synonyms: development of a plant organ
mitotic sister chromatid cohesion, telomeric (GO:0099404)
Namespace: biological_process
Definition: The cell cycle process in which telomeres of sister chromatids are joined during mitosis.
Synonyms: mitotic sister chromatid cohesion at telomere; sister chromatid cohesion at telomere at mitosis; telomeric mitotic sister chromatin cohesion
vesicle fusion to plasma membrane (GO:0099500)
Namespace: biological_process
Definition: Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
exocytic vesicle membrane (GO:0099501)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an exocytic vesicle.
Synonyms: secretory vesicle membrane
calcium-dependent activation of synaptic vesicle fusion (GO:0099502)
Namespace: biological_process
Definition: The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.
secretory vesicle (GO:0099503)
Namespace: cellular_component
Definition: A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
synaptic vesicle cycle (GO:0099504)
Namespace: biological_process
Definition: A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.
regulation of presynaptic membrane potential (GO:0099505)
Namespace: biological_process
Definition: Any process that modulates the potential difference across a presynaptic membrane.
Synonyms: regulation of pre-synaptic membrane potential
synaptic vesicle transport along actin filament (GO:0099506)
Namespace: biological_process
Definition: The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.
ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (GO:0099507)
Namespace: molecular_function
Definition: Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
Synonyms: ligand gated ion channel activity involved in regulation of presynaptic membrane potential; ligand-dependent ion channel activity involved in regulation of pre-synaptic membrane potential; ligand-dependent ion channel activity involved in regulation of presynaptic membrane potential; ligand-gated ion channel activity involved in regulation of pre-synaptic membrane potential; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential
voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (GO:0099508)
Namespace: molecular_function
Definition: Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
Synonyms: voltage gated ion channel activity involved in regulation of presynaptic membrane potential; voltage-dependent ion channel activity involved in regulation of pre-synaptic membrane potential; voltage-dependent ion channel activity involved in regulation of presynaptic membrane potential; voltage-gated ion channel activity involved in regulation of pre-synaptic membrane potential; voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
regulation of presynaptic cytosolic calcium ion concentration (GO:0099509)
Namespace: biological_process
Definition: Any process that regulates the concentration of calcium in the presynaptic cytosol.
Synonyms: regulation of presynaptic cytosolic calcium levels