LiteFold/GO huggingface dataset:
neuropore closure (GO:0021995)
Namespace: biological_process
Definition: The process of joining together the neural folds at either end of the neural tube.
lamina terminalis formation (GO:0021996)
Namespace: biological_process
Definition: The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.
neural plate axis specification (GO:0021997)
Namespace: biological_process
Definition: The pattern specification process in which the axes of the nervous system are established.
Synonyms: neural plate axis determination
neural plate mediolateral regionalization (GO:0021998)
Namespace: biological_process
Definition: The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.
Synonyms: neural plate mediolateral pattern formation
neural plate anterior/posterior regionalization (GO:0021999)
Namespace: biological_process
Definition: The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.
Synonyms: neural plate anterior/posterior pattern formation
forebrain induction by the anterior neural ridge (GO:0022000)
Namespace: biological_process
Definition: The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.
negative regulation of anterior neural cell fate commitment of the neural plate (GO:0022001)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.
Synonyms: caudalization of neural plate; down regulation of anterior neural cell fate of the neural plate; down-regulation of anterior neural cell fate of the neural plate; downregulation of anterior neural cell fate of the neural plate; inhibition of anterior neural cell fate of the neural plate; negative regulation of anterior neural cell fate of the neural plate; posteriorization
obsolete negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway (GO:0022002)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.
Synonyms: negative regulation of anterior neural cell fate commitment of the neural plate by Wnt receptor signaling pathway; negative regulation of anterior neural cell fate commitment of the neural plate by Wnt-activated signaling pathway; Wnt receptor signaling involved in down regulation of anterior neural cell fate of the neural plate; Wnt receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate; Wnt receptor signaling involved in downregulation of anterior neural cell fate of the neural plate; Wnt receptor signaling involved in inhibition of anterior neural cell fate of the neural plate; Wnt receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate; Wnt receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate
Comment: This term was obsoleted because it represents a GO-CAM model.
negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway (GO:0022003)
Namespace: biological_process
Definition: The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
Synonyms: fgf receptor signaling involved in down regulation of anterior neural cell fate of the neural plate; fgf receptor signaling involved in down-regulation of anterior neural cell fate of the neural plate; fgf receptor signaling involved in downregulation of anterior neural cell fate of the neural plate; fgf receptor signaling involved in inhibition of anterior neural cell fate of the neural plate; fgf receptor signaling involved in negative regulation of anterior neural cell fate of the neural plate; fgf receptor signalling involved in negative regulation of anterior neural cell fate of the neural plate
midbrain-hindbrain boundary maturation during brain development (GO:0022004)
Namespace: biological_process
Definition: A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
midbrain-hindbrain boundary maturation during neural plate development (GO:0022005)
Namespace: biological_process
Definition: A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms: midbrain-hindbrain boundary maturation involved in neural plate development
convergent extension involved in neural plate elongation (GO:0022007)
Namespace: biological_process
Definition: The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.
neurogenesis (GO:0022008)
Namespace: biological_process
Definition: Generation of cells within the nervous system.
Synonyms: nervous system cell generation; neural cell differentiation
central nervous system vasculogenesis (GO:0022009)
Namespace: biological_process
Definition: The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.
central nervous system myelination (GO:0022010)
Namespace: biological_process
Definition: The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Synonyms: myelination in central nervous system
myelination in peripheral nervous system (GO:0022011)
Namespace: biological_process
Definition: The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
Synonyms: peripheral nervous system myelination
subpallium cell proliferation in forebrain (GO:0022012)
Namespace: biological_process
Definition: The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.
pallium cell proliferation in forebrain (GO:0022013)
Namespace: biological_process
Definition: The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.
obsolete radial glial cell division in subpallium (GO:0022014)
Namespace: biological_process
Definition: OBSOLETE. The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
Comment: This term was obsoleted because it represents a GO-CAM model.
radial glial cell division in pallium (GO:0022015)
Namespace: biological_process
Definition: The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
pallium glioblast division (GO:0022016)
Namespace: biological_process
Definition: The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.
Synonyms: glioblast cell division in pallium
neuroblast division in pallium (GO:0022017)
Namespace: biological_process
Definition: The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.
lateral ganglionic eminence cell proliferation (GO:0022018)
Namespace: biological_process
Definition: The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.
dorsal lateral ganglionic eminence cell proliferation (GO:0022019)
Namespace: biological_process
Definition: The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.
medial ganglionic eminence cell proliferation (GO:0022020)
Namespace: biological_process
Definition: The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.
caudal ganglionic eminence cell proliferation (GO:0022021)
Namespace: biological_process
Definition: The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.
septal cell proliferation (GO:0022022)
Namespace: biological_process
Definition: The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.
Synonyms: septum cell proliferation
radial glial cell fate commitment in forebrain (GO:0022023)
Namespace: biological_process
Definition: The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.
obsolete BMP signaling pathway involved in forebrain neuron fate commitment (GO:0022024)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
Synonyms: BMP signalling pathway involved in forebrain neuron fate commitment; bone morphogenetic protein signaling pathway involved in forebrain neuron fate commitment; bone morphogenetic protein signalling pathway involved in forebrain neuron fate commitment
Comment: This term was obsoleted because it represents a GO-CAM model.
interkinetic nuclear migration (GO:0022027)
Namespace: biological_process
Definition: The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.
telencephalon cell migration (GO:0022029)
Namespace: biological_process
Definition: The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.
telencephalon glial cell migration (GO:0022030)
Namespace: biological_process
Definition: The orderly movement of glial cells through the telencephalon.
telencephalon astrocyte cell migration (GO:0022031)
Namespace: biological_process
Definition: The orderly movement of an astrocyte cell through the telencephalon.
telencephalon oligodendrocyte cell migration (GO:0022032)
Namespace: biological_process
Definition: The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.
telencephalon microglial cell migration (GO:0022033)
Namespace: biological_process
Definition: The orderly movement of microglial cells through the telencephalon.
rhombomere cell proliferation (GO:0022034)
Namespace: biological_process
Definition: The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.
rhombomere cell migration (GO:0022035)
Namespace: biological_process
Definition: The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
rhombomere cell differentiation (GO:0022036)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.
metencephalon development (GO:0022037)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.
corpus callosum development (GO:0022038)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.
regulation of opsin-mediated signaling pathway (GO:0022400)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of opsin-mediated signaling.
Synonyms: regulation of rhodopsin mediated signaling pathway; regulation of rhodopsin mediated signalling; regulation of rhodopsin-mediated signaling pathway
negative adaptation of signaling pathway (GO:0022401)
Namespace: biological_process
Definition: The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
Synonyms: negative adaptation of signal transduction pathway; negative adaptation of signalling pathway
cell cycle phase (GO:0022403)
Namespace: biological_process
Definition: One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
molting cycle process (GO:0022404)
Namespace: biological_process
Definition: A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.
hair cycle process (GO:0022405)
Namespace: biological_process
Definition: A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
membrane docking (GO:0022406)
Namespace: biological_process
Definition: The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
regulation of cell-cell adhesion (GO:0022407)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
positive regulation of cell-cell adhesion (GO:0022409)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of cell adhesion to another cell.
Synonyms: activation of cell-cell adhesion; stimulation of cell-cell adhesion; up regulation of cell-cell adhesion; up-regulation of cell-cell adhesion; upregulation of cell-cell adhesion
circadian sleep/wake cycle process (GO:0022410)
Namespace: biological_process
Definition: A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
cellular component disassembly (GO:0022411)
Namespace: biological_process
Definition: A cellular process that results in the breakdown of a cellular component.
Synonyms: cell structure disassembly; cellular component disassembly at cellular level
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cellular process involved in reproduction in multicellular organism (GO:0022412)
Namespace: biological_process
Definition: A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.
Synonyms: reproductive cellular process in multicellular organism
reproductive process in single-celled organism (GO:0022413)
Namespace: biological_process
Definition: A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.
reproductive process (GO:0022414)
Namespace: biological_process
Definition: A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
Synonyms: single organism reproductive process
chaeta development (GO:0022416)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
Synonyms: bristle development
obsolete protein maturation by protein folding (GO:0022417)
Namespace: biological_process
Definition: OBSOLETE. The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.
Comment: The reason for obsoletion is that these BP terms represent MFs.
menstrual cycle phase (GO:0022601)
Namespace: biological_process
Definition: The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
ovulation cycle process (GO:0022602)
Namespace: biological_process
Definition: A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
Synonyms: estrous cycle process; menstrual cycle process
regulation of anatomical structure morphogenesis (GO:0022603)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
Synonyms: regulation of morphogenesis
regulation of cell morphogenesis (GO:0022604)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
Synonyms: negative regulation of cell shape and cell size; positive regulation of cell shape and cell size; regulation of cell shape and cell size
establishment of proximal/distal cell polarity (GO:0022606)
Namespace: biological_process
Definition: The specification and formation of the polarity of a cell along its proximal/distal axis.
cellular component assembly (GO:0022607)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a cellular component.
Synonyms: cell structure assembly; cellular component assembly at cellular level
multicellular organism adhesion (GO:0022608)
Namespace: biological_process
Definition: The attachment of a multicellular organism to a substrate or other organism.
multicellular organism adhesion to substrate (GO:0022609)
Namespace: biological_process
Definition: The attachment of a multicellular organism to a surface or material.
obsolete biological adhesion (GO:0022610)
Namespace: biological_process
Definition: OBSOLETE. The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
Comment: This term was obsoleted because it represents an unnecessary grouping class by mixing cellular and multi-cellular organism level processes.
dormancy process (GO:0022611)
Namespace: biological_process
Definition: A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.
Synonyms: multicellular organism dormancy process; spore dormancy process
Comment: In plants and animals, dormancy may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. In plants, dormancy may involve the formation of dormant buds, and may be preceded by the senescence of plant parts such as leaves in woody plants or most of the shoot system in herbaceous perennials. The exit from dormancy in vascular plants is marked by resumed growth of buds and/or growth of vascular cambium.
gland morphogenesis (GO:0022612)
Namespace: biological_process
Definition: The process in which the anatomical structures of a gland are generated and organized.
ribonucleoprotein complex biogenesis (GO:0022613)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.
Synonyms: ribonucleoprotein complex biogenesis and assembly; RNA-protein complex biogenesis
membrane to membrane docking (GO:0022614)
Namespace: biological_process
Definition: The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.
Synonyms: membrane-membrane docking
protein to membrane docking (GO:0022615)
Namespace: biological_process
Definition: The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.
Synonyms: protein-membrane docking
extracellular matrix disassembly (GO:0022617)
Namespace: biological_process
Definition: A process that results in the breakdown of the extracellular matrix.