LiteFold/GO huggingface dataset:
short nephron development (GO:0072030)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.
proximal convoluted tubule segment 1 development (GO:0072031)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
Synonyms: S1 development
proximal convoluted tubule segment 2 development (GO:0072032)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.
Synonyms: S2 development
renal vesicle formation (GO:0072033)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
Synonyms: nephron epithelium formation
renal vesicle induction (GO:0072034)
Namespace: biological_process
Definition: Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.
Synonyms: nephron induction; positive regulation of nephron formation
pre-tubular aggregate formation (GO:0072035)
Namespace: biological_process
Definition: The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.
Synonyms: mesenchymal cell condensation involved in renal vesicle formation; nephron epithelium formation
obsolete mesenchymal to epithelial transition involved in renal vesicle formation (GO:0072036)
Namespace: biological_process
Definition: OBSOLETE. A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete mesenchymal stem cell differentiation involved in nephron morphogenesis (GO:0072037)
Namespace: biological_process
Definition: OBSOLETE. The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mesenchymal stem cell maintenance involved in nephron morphogenesis (GO:0072038)
Namespace: biological_process
Definition: The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
obsolete regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072039)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
Synonyms: regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis; regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072040)
Namespace: biological_process
Definition: Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
Synonyms: negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis; negative regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis
obsolete positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072041)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
Synonyms: positive regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis; positive regulation of mesenchymal stem cell apoptotic process involved in nephron morphogenesis
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis (GO:0072042)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
collecting duct development (GO:0072044)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
convergent extension involved in nephron morphogenesis (GO:0072045)
Namespace: biological_process
Definition: The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.
establishment of planar polarity involved in nephron morphogenesis (GO:0072046)
Namespace: biological_process
Definition: Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.
Synonyms: establishment of planar cell polarity involved in nephron morphogenesis
proximal/distal pattern formation involved in nephron development (GO:0072047)
Namespace: biological_process
Definition: The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
Synonyms: proximal-distal pattern formation involved in nephron development; proximal/distal nephron patterning
comma-shaped body morphogenesis (GO:0072049)
Namespace: biological_process
Definition: The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.
S-shaped body morphogenesis (GO:0072050)
Namespace: biological_process
Definition: The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.
juxtaglomerular apparatus development (GO:0072051)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.
juxtaglomerulus cell differentiation (GO:0072052)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.
renal inner medulla development (GO:0072053)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.
Synonyms: inner renal medulla development
renal outer medulla development (GO:0072054)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.
Synonyms: outer renal medulla development
renal cortex development (GO:0072055)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.
pyramid development (GO:0072056)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.
Synonyms: kidney pyramid development; pyramids development; renal medulla development; renal pyramid development
inner stripe development (GO:0072057)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.
outer stripe development (GO:0072058)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.
cortical collecting duct development (GO:0072059)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.
outer medullary collecting duct development (GO:0072060)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.
inner medullary collecting duct development (GO:0072061)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.
proximal convoluted tubule segment 1 cell differentiation (GO:0072062)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.
Synonyms: S1 cell differentiation
short descending thin limb development (GO:0072063)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.
long descending thin limb development (GO:0072064)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.
long descending thin limb bend development (GO:0072065)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.
prebend segment development (GO:0072066)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
early distal convoluted tubule development (GO:0072067)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.
late distal convoluted tubule development (GO:0072068)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
DCT cell differentiation (GO:0072069)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.
Synonyms: distal convoluted tubule cell differentiation
loop of Henle development (GO:0072070)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.
Synonyms: intermediate tubule development
kidney interstitial fibroblast differentiation (GO:0072071)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.
Synonyms: kidney interstitial cell differentiation
kidney epithelium development (GO:0072073)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
metanephric mesenchyme development (GO:0072075)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
renal vesicle morphogenesis (GO:0072077)
Namespace: biological_process
Definition: The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
nephron tubule morphogenesis (GO:0072078)
Namespace: biological_process
Definition: The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
nephron tubule formation (GO:0072079)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
nephron tubule development (GO:0072080)
Namespace: biological_process
Definition: The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
specification of nephron tubule identity (GO:0072081)
Namespace: biological_process
Definition: The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.
specification of proximal tubule identity (GO:0072082)
Namespace: biological_process
Definition: The process in which the proximal tubule of the kidney nephron acquires its identity.
specification of distal tubule identity (GO:0072084)
Namespace: biological_process
Definition: The process in which the distal tubule of the kidney nephron acquires its identity.
specification of connecting tubule identity (GO:0072085)
Namespace: biological_process
Definition: The process in which the connecting tubule of the kidney nephron acquires its identity.
specification of loop of Henle identity (GO:0072086)
Namespace: biological_process
Definition: The process in which the loop of Henle of the kidney nephron acquires its identity.
Synonyms: specification of intermediate tubule identity
renal vesicle development (GO:0072087)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
nephron epithelium morphogenesis (GO:0072088)
Namespace: biological_process
Definition: The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.
obsolete mesenchymal stem cell proliferation involved in nephron morphogenesis (GO:0072090)
Namespace: biological_process
Definition: OBSOLETE. The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
ureteric bud invasion (GO:0072092)
Namespace: biological_process
Definition: The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.
metanephric renal vesicle formation (GO:0072093)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of the metanephros.
Synonyms: metanephros formation
metanephric renal vesicle induction (GO:0072094)
Namespace: biological_process
Definition: Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.
Synonyms: positive regulation of metanephros formation
regulation of branch elongation involved in ureteric bud branching (GO:0072095)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
obsolete negative regulation of branch elongation involved in ureteric bud branching (GO:0072096)
Namespace: biological_process
Definition: OBSOLETE. Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway (GO:0072097)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
Synonyms: negative regulation of branch elongation involved in ureteric bud branching by BMP signalling pathway
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete anterior/posterior pattern specification involved in kidney development (GO:0072098)
Namespace: biological_process
Definition: OBSOLETE. The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
Synonyms: anterior/posterior pattern formation involved in kidney development; kidney anterior/posterior pattern formation; kidney anterior/posterior pattern specification
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
anterior/posterior pattern specification involved in ureteric bud development (GO:0072099)
Namespace: biological_process
Definition: The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
Synonyms: ureteric bud anterior/posterior pattern formation
specification of ureteric bud anterior/posterior symmetry (GO:0072100)
Namespace: biological_process
Definition: The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
Synonyms: specification of ureteric bud anterior/posterior asymmetry
obsolete specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway (GO:0072101)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
Synonyms: specification of ureteric bud anterior/posterior asymmetry by BMP signaling pathway; specification of ureteric bud anterior/posterior symmetry by BMP signalling pathway
Comment: This term was obsoleted because it represents a GO-CAM model.
glomerulus morphogenesis (GO:0072102)
Namespace: biological_process
Definition: The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.