LiteFold/GO huggingface dataset:
IgD immunoglobulin complex (GO:0071738)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgD immunoglobulin complex, circulating (GO:0071739)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: IgD antibody
Comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgD B cell receptor complex (GO:0071740)
Namespace: cellular_component
Definition: An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
Synonyms: membrane-bound IgD; surface IgD
Comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgD immunoglobulin complex, GPI-anchored (GO:0071741)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.
Synonyms: GPI-anchored IgD
Comment: Note that an IgD immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgE immunoglobulin complex (GO:0071742)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgE immunoglobulin complex, circulating (GO:0071743)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: IgE antibody
Comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgE B cell receptor complex (GO:0071744)
Namespace: cellular_component
Definition: An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
Synonyms: membrane-bound IgE; surface IgE
Comment: Note that an IgE immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgA immunoglobulin complex (GO:0071745)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: IgA1 antibody; IgA2 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgA immunoglobulin complex, circulating (GO:0071746)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: IgA antibody; IgA1 antibody; IgA2 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgA B cell receptor complex (GO:0071747)
Namespace: cellular_component
Definition: An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
Synonyms: membrane-bound IgA; membrane-bound IgA1; membrane-bound IgA2; surface IgA; surface IgA1; surface IgA2
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
monomeric IgA immunoglobulin complex (GO:0071748)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: monomeric IgA antibody; monomeric IgA1 antibody; monomeric IgA2 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
polymeric IgA immunoglobulin complex (GO:0071749)
Namespace: cellular_component
Definition: A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: pIgA antibody; pIgA1 antibody; polymeric IgA antibody; polymeric IgA1 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a polymeric forms.
dimeric IgA immunoglobulin complex (GO:0071750)
Namespace: cellular_component
Definition: A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: dimeric IgA antibody; dimeric IgA1 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.
secretory IgA immunoglobulin complex (GO:0071751)
Namespace: cellular_component
Definition: A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.
Synonyms: secretory IgA antibody; sIgA antibody; sIgA1 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.
secretory dimeric IgA immunoglobulin complex (GO:0071752)
Namespace: cellular_component
Definition: A dimeric form of secretory IgA immunoglobulin complex.
Synonyms: secretory dimeric IgA antibody; secretory dimeric IgA1 antibody
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.
IgM immunoglobulin complex (GO:0071753)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgM immunoglobulin complex, circulating (GO:0071754)
Namespace: cellular_component
Definition: A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.
Synonyms: IgM antibody
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgM B cell receptor complex (GO:0071755)
Namespace: cellular_component
Definition: An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
Synonyms: membrane-bound IgM; surface IgM
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
pentameric IgM immunoglobulin complex (GO:0071756)
Namespace: cellular_component
Definition: A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.
Synonyms: pentameric IgM antibody
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
hexameric IgM immunoglobulin complex (GO:0071757)
Namespace: cellular_component
Definition: A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.
Synonyms: hexameric IgM antibody
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgW immunoglobulin complex (GO:0071758)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgW immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgW is found in fish.
IgX immunoglobulin complex (GO:0071759)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgX immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgX is found in amphibians.
IgY immunoglobulin complex (GO:0071760)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Comment: Note that an IgY immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgY is found in amphibians, reptiles, and birds.
IgZ immunoglobulin complex (GO:0071761)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.
Synonyms: IgT antibody; IgT immunoglobulin complex; IgZ antibody
Comment: Note that an IgZ immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgZ is found in bony fish, and called IgT in certain species, such as trout.
heavy chain immunoglobulin complex (GO:0071762)
Namespace: cellular_component
Definition: A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.
Synonyms: HCab; Ig NAR immunoglobulin complex; IgNAR antibody; IgNAR immunoglobulin complex
Comment: Note that a heavy chain immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Note that IgNAR is found in serum of cartilaginous fish as a heavy chain dimer without immunoglobulin light chains. Note that HCab is found in camels as a heavy chain dimer without immunoglobulin light chains.
nuclear membrane organization (GO:0071763)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.
Synonyms: nuclear membrane organisation; nuclear membrane organization and biogenesis
nuclear inner membrane organization (GO:0071765)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.
Synonyms: nuclear inner membrane organisation; nuclear inner membrane organization and biogenesis
Actinobacterium-type cell wall biogenesis (GO:0071766)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
obsolete mycolic acid metabolic process (GO:0071767)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
Synonyms: mycolate metabolic process; mycolic acid metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
mycolic acid biosynthetic process (GO:0071768)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
Synonyms: mycolate biosynthetic process; mycolic acid anabolism; mycolic acid biosynthesis; mycolic acid formation; mycolic acid synthesis
mycolate cell wall layer assembly (GO:0071769)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.
Synonyms: mycolate cell wall layer biogenesis
DIM/DIP cell wall layer assembly (GO:0071770)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
Synonyms: DIM cell wall layer assembly; DIM/DIP cell wall layer biogenesis; PDIM cell wall layer assembly
aldehyde oxygenase (deformylating) activity (GO:0071771)
Namespace: molecular_function
Definition: Catalysis of the reaction: a long-chain fatty aldehyde + H+ + 2 NADPH + O2 = a long-chain alkane + formate + H2O + 2 NADP+.
Synonyms: aldehyde decarbonylase activity; decarbonylase activity
response to BMP (GO:0071772)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
Synonyms: response to BMP stimulus; response to bone morphogenetic protein stimulus
cellular response to BMP stimulus (GO:0071773)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
Synonyms: cellular response to bone morphogenetic protein stimulus
response to fibroblast growth factor (GO:0071774)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.
Synonyms: response to FGF stimulus; response to fibroblast growth factor stimulus
obsolete WINAC complex (GO:0071778)
Namespace: cellular_component
Definition: OBSOLETE. A SWI/SNF-type complex that directly interacts with the vitamin D receptor (VDR) through the Williams syndrome transcription factor (WSTF), and mediates the recruitment of unliganded VDR to VDR target sites in promoters. The WINAC complex contains at least 13 subunits, including WSTF, several SWI/SNF components, and DNA replication-related factors.
Synonyms: WINAC complex
Comment: This term was made obsolete because the paper describing the characterization of this complex, which was used to create this term, has been retracted.
endoplasmic reticulum cisternal network (GO:0071781)
Namespace: cellular_component
Definition: A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells.
Synonyms: ER cisternal network
endoplasmic reticulum tubular network (GO:0071782)
Namespace: cellular_component
Definition: A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
Synonyms: ER tubular network
endoplasmic reticulum cisternal network organization (GO:0071783)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
Synonyms: endoplasmic reticulum cisternal network organisation; ER cisternal network organisation; ER cisternal network organization
endoplasmic reticulum cisternal network maintenance (GO:0071785)
Namespace: biological_process
Definition: The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
Synonyms: ER cisternal network maintenance
endoplasmic reticulum tubular network organization (GO:0071786)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
Synonyms: endoplasmic reticulum tubular network organisation; ER tubular network organisation; ER tubular network organization
endoplasmic reticulum tubular network maintenance (GO:0071788)
Namespace: biological_process
Definition: The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
Synonyms: ER tubular network maintenance
chemokine (C-C motif) ligand 5 binding (GO:0071791)
Namespace: molecular_function
Definition: Binding to chemokine (C-C motif) ligand 5.
Synonyms: CCL5 binding; RANTES binding; Regulated upon Activation, Normal T-cell Expressed, and Secreted binding
obsolete bacillithiol metabolic process (GO:0071792)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
Synonyms: bacillithiol metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
bacillithiol biosynthetic process (GO:0071793)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
Synonyms: bacillithiol anabolism; bacillithiol biosynthesis; bacillithiol formation; bacillithiol synthesis
CAP-Gly domain binding (GO:0071794)
Namespace: molecular_function
Definition: Binding to a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.
K11-linked polyubiquitin modification-dependent protein binding (GO:0071795)
Namespace: molecular_function
Definition: Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 11 in the target protein.
K6-linked polyubiquitin modification-dependent protein binding (GO:0071796)
Namespace: molecular_function
Definition: Binding to a protein upon poly-ubiquitination formed by linkages between lysine residues at position 6 in the target protein.