LiteFold/GO huggingface dataset:
BRCA1-BARD1 complex (GO:0031436)
Namespace: cellular_component
Definition: A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.
obsolete regulation of mRNA cleavage (GO:0031437)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
Comment: This term was obsoleted because it represents a molecular function
obsolete negative regulation of mRNA cleavage (GO:0031438)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.
Synonyms: down regulation of mRNA cleavage; down-regulation of mRNA cleavage; downregulation of mRNA cleavage; inhibition of mRNA cleavage
Comment: This term was obsoleted because it represents a molecular function
obsolete positive regulation of mRNA cleavage (GO:0031439)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of mRNA cleavage.
Synonyms: activation of mRNA cleavage; stimulation of mRNA cleavage; up regulation of mRNA cleavage; up-regulation of mRNA cleavage; upregulation of mRNA cleavage
Comment: This term was obsoleted because it represents a molecular function
regulation of mRNA 3'-end processing (GO:0031440)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
positive regulation of mRNA 3'-end processing (GO:0031442)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
Synonyms: activation of mRNA 3'-end processing; stimulation of mRNA 3'-end processing; up regulation of mRNA 3'-end processing; up-regulation of mRNA 3'-end processing; upregulation of mRNA 3'-end processing
fast-twitch skeletal muscle fiber contraction (GO:0031443)
Namespace: biological_process
Definition: A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
Synonyms: fast-twitch skeletal fiber contraction; fast-twitch skeletal fibre contraction; fast-twitch skeletal muscle fibre contraction; fast-twitch skeletal myofiber contraction; fast-twitch skeletal myofibre contraction
slow-twitch skeletal muscle fiber contraction (GO:0031444)
Namespace: biological_process
Definition: A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
Synonyms: slow-twitch skeletal muscle fibre contraction
regulation of heterochromatin formation (GO:0031445)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
Synonyms: regulation of heterochromatin assembly
regulation of fast-twitch skeletal muscle fiber contraction (GO:0031446)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.
Synonyms: regulation of fast-twitch skeletal muscle contraction
negative regulation of fast-twitch skeletal muscle fiber contraction (GO:0031447)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.
Synonyms: down regulation of fast-twitch skeletal muscle contraction; down-regulation of fast-twitch skeletal muscle contraction; downregulation of fast-twitch skeletal muscle contraction; inhibition of fast-twitch skeletal muscle contraction; negative regulation of fast-twitch skeletal muscle contraction
positive regulation of fast-twitch skeletal muscle fiber contraction (GO:0031448)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.
Synonyms: activation of fast-twitch skeletal muscle contraction; positive regulation of fast-twitch skeletal muscle contraction; stimulation of fast-twitch skeletal muscle contraction; up regulation of fast-twitch skeletal muscle contraction; up-regulation of fast-twitch skeletal muscle contraction; upregulation of fast-twitch skeletal muscle contraction
regulation of slow-twitch skeletal muscle fiber contraction (GO:0031449)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.
Synonyms: regulation of slow-twitch skeletal muscle contraction
negative regulation of slow-twitch skeletal muscle fiber contraction (GO:0031450)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.
Synonyms: down regulation of slow-twitch skeletal muscle contraction; down-regulation of slow-twitch skeletal muscle contraction; downregulation of slow-twitch skeletal muscle contraction; inhibition of slow-twitch skeletal muscle contraction; negative regulation of slow-twitch skeletal muscle contraction
positive regulation of slow-twitch skeletal muscle fiber contraction (GO:0031451)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.
Synonyms: activation of slow-twitch skeletal muscle contraction; positive regulation of slow-twitch skeletal muscle contraction; stimulation of slow-twitch skeletal muscle contraction; up regulation of slow-twitch skeletal muscle contraction; up-regulation of slow-twitch skeletal muscle contraction; upregulation of slow-twitch skeletal muscle contraction
negative regulation of heterochromatin formation (GO:0031452)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
Synonyms: chromatin decompaction; chromatin decondensation; down regulation of heterochromatin formation; down-regulation of heterochromatin formation; downregulation of heterochromatin formation; inhibition of heterochromatin formation; negative regulation of heterochromatin assembly
positive regulation of heterochromatin formation (GO:0031453)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of heterochromatin formation.
Synonyms: activation of heterochromatin formation; positive regulation of heterochromatin assembly; stimulation of heterochromatin formation; up regulation of heterochromatin formation; up-regulation of heterochromatin formation; upregulation of heterochromatin formation
obsolete glycine betaine metabolic process (GO:0031455)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.
Synonyms: glycine betaine metabolism; N-trimethylglycine metabolic process; N-trimethylglycine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
glycine betaine biosynthetic process (GO:0031456)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.
Synonyms: glycine betaine anabolism; glycine betaine biosynthesis; glycine betaine formation; glycine betaine synthesis; N-trimethylglycine biosynthesis; N-trimethylglycine biosynthetic process
glycine betaine catabolic process (GO:0031457)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.
Synonyms: glycine betaine breakdown; glycine betaine catabolism; glycine betaine degradation; N-trimethylglycine catabolic process; N-trimethylglycine catabolism
ABC-type betaine transporter activity (GO:0031458)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).
Synonyms: ABC-type betaine transmembrane transporter activity; ATP-dependent betaine transporter activity; ATPase-coupled betaine transporter activity; betaine ABC transporter; betaine-transporting ATPase activity
ABC-type glycine betaine transporter activity (GO:0031459)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).
Synonyms: ATP-dependent glycine betaine transporter activity; ATPase-coupled glycine betaine transporter activity; glycine betaine ABC transporter; glycine betaine-transporting ATPase activity; N-trimethylglycine-transporting ATPase activity
glycine betaine transport (GO:0031460)
Namespace: biological_process
Definition: The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: N-trimethylglycine transport
cullin-RING ubiquitin ligase complex (GO:0031461)
Namespace: cellular_component
Definition: Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.
Synonyms: CRL complex; cullin complex; cullin-RING ligase
Cul2-RING ubiquitin ligase complex (GO:0031462)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
Synonyms: CBC complex; CDL2 complex; CRL2 complex; cullin-RING ligase 2; EC2S complex; ECS complex; SCF2 complex; VBC complex
Cul3-RING ubiquitin ligase complex (GO:0031463)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
Synonyms: BC3B complex; BCR3 complex; CDL3 complex; CRL3 complex; cullin-RING ligase 3; SCF3 complex
Cul4A-RING E3 ubiquitin ligase complex (GO:0031464)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
Synonyms: CDL4 complex; CRL4 complex; cullin-RING ligase 4A; DCX complex; SCF4 complex; VDC complex
Cul4B-RING E3 ubiquitin ligase complex (GO:0031465)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.
Synonyms: cullin-RING ligase 4B
Cul7-RING ubiquitin ligase complex (GO:0031467)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.
Synonyms: CDL7 complex; CRL7 complex; cullin-RING ligase 7; SCF7 complex
nuclear membrane reassembly (GO:0031468)
Namespace: biological_process
Definition: The reformation of the nuclear membranes following their breakdown in the context of a normal process.
Synonyms: nuclear envelope reassembly
bacterial microcompartment (GO:0031469)
Namespace: cellular_component
Definition: An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
Synonyms: BAC; BMC; MCP; polyhedral organelle
carboxysome (GO:0031470)
Namespace: cellular_component
Definition: An organelle consisting of a proteinaceous coat and enzymes for the fixation of CO2. It augments the concentration of CO2 in the vicinity of RuBisCO to increase the efficiency of CO2 fixation under atmospheric conditions.
ethanolamine degradation polyhedral organelle (GO:0031471)
Namespace: cellular_component
Definition: An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.
Synonyms: ethanolamine metabolosome
propanediol degradation polyhedral organelle (GO:0031472)
Namespace: cellular_component
Definition: An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.
myosin III binding (GO:0031473)
Namespace: molecular_function
Definition: Binding to a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
myosin IV complex (GO:0031474)
Namespace: cellular_component
Definition: A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.
myosin V complex (GO:0031475)
Namespace: cellular_component
Definition: A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.
myosin VII complex (GO:0031477)
Namespace: cellular_component
Definition: A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.
myosin VIII complex (GO:0031478)
Namespace: cellular_component
Definition: A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.
myosin IX complex (GO:0031479)
Namespace: cellular_component
Definition: A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.
myosin X complex (GO:0031480)
Namespace: cellular_component
Definition: A myosin complex containing one or more class X myosin heavy chains and associated light chains.
myosin XI complex (GO:0031481)
Namespace: cellular_component
Definition: A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.
myosin XII complex (GO:0031482)
Namespace: cellular_component
Definition: A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.
myosin XIII complex (GO:0031483)
Namespace: cellular_component
Definition: A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.
myosin XIV complex (GO:0031484)
Namespace: cellular_component
Definition: A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
myosin XV complex (GO:0031485)
Namespace: cellular_component
Definition: A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.
myosin XVI complex (GO:0031486)
Namespace: cellular_component
Definition: A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.
myosin XVII complex (GO:0031487)
Namespace: cellular_component
Definition: A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.
myosin XVIII complex (GO:0031488)
Namespace: cellular_component
Definition: A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.
myosin V binding (GO:0031489)
Namespace: molecular_function
Definition: Binding to a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
chromatin DNA binding (GO:0031490)
Namespace: molecular_function
Definition: Binding to DNA that is assembled into chromatin.
nucleosome binding (GO:0031491)
Namespace: molecular_function
Definition: Binding to a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
nucleosomal DNA binding (GO:0031492)
Namespace: molecular_function
Definition: Binding to the DNA portion of a nucleosome.
obsolete nucleosomal histone binding (GO:0031493)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a histone that is assembled into a nucleosome.
Comment: This term was obsoleted because it represents both an activity and a cellular component.
regulation of mating type switching (GO:0031494)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.
negative regulation of mating type switching (GO:0031495)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.
Synonyms: down regulation of mating type switching; down-regulation of mating type switching; downregulation of mating type switching; inhibition of mating type switching
obsolete chromatin disassembly (GO:0031498)
Namespace: biological_process
Definition: OBSOLETE. The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.
Synonyms: chromatin maintenance
Comment: This term has been obsoleted because this process doesn't happen independently from assembly and is always tied to chromatin remodeling.
TRAMP complex (GO:0031499)
Namespace: cellular_component
Definition: A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
Synonyms: TRAMP4 complex; TRAMP5 complex; Trf4 complex; Trf4 poly(A) polymerase complex; Trf4p-Air2p-Mtr4p polyadenylation complex
Tea1 cell-end complex (GO:0031500)
Namespace: cellular_component
Definition: A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
mannosyltransferase complex (GO:0031501)
Namespace: cellular_component
Definition: A complex that possesses mannosyltransferase activity.
dolichyl-phosphate-mannose-protein mannosyltransferase complex (GO:0031502)
Namespace: cellular_component
Definition: A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.
Synonyms: PMT family mannosyltransferase complex; protein O-mannosyltransferase complex
Comment: Note that GO:0004169 'dolichyl-phosphate-mannose-protein mannosyltransferase activity' (part of protein O-linked mannosylation) has never been observed in green plants. However, N- and C-mannosylation may occur in these species; see figure 1 in PMID:21558543.
protein-containing complex localization (GO:0031503)
Namespace: biological_process
Definition: A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
Synonyms: cellular protein complex localisation; cellular protein complex localization; cellular protein-containing complex localization; establishment and maintenance of cellular protein complex localization; establishment and maintenance of protein complex localization; protein complex localisation; protein complex localization
peptidoglycan-based cell wall organization (GO:0031504)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.
Synonyms: peptidoglycan-based cell wall organisation; peptidoglycan-based cell wall organization and biogenesis
fungal-type cell wall organization (GO:0031505)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
Synonyms: beta-glucan-containing cell wall organization and biogenesis; chitin- and beta-glucan-containing cell wall organisation; chitin- and beta-glucan-containing cell wall organization and biogenesis; chitin-containing cell wall organization and biogenesis; fungal-type cell wall organization and biogenesis
cell wall glycoprotein biosynthetic process (GO:0031506)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.
Synonyms: cell wall glycoprotein anabolism; cell wall glycoprotein biosynthesis; cell wall glycoprotein formation; cell wall glycoprotein synthesis