LiteFold/GO huggingface dataset:
chemokine (C-X-C motif) ligand 2 production (GO:0072567)
Namespace: biological_process
Definition: The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CXCL2 production; MIP-2 production; MIP2 production; SCYB2 production
ADP-D-ribose binding (GO:0072570)
Namespace: molecular_function
Definition: Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
Synonyms: ADP-ribose binding
mono-ADP-D-ribose binding (GO:0072571)
Namespace: molecular_function
Definition: Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
Synonyms: mADPr binding; mono-ADP-ribose binding
tolerance induction to lipopolysaccharide (GO:0072573)
Namespace: biological_process
Definition: Tolerance induction directed at lipopolysaccharide antigens.
Synonyms: tolerance induction to endotoxin; tolerance induction to LPS
hepatocyte proliferation (GO:0072574)
Namespace: biological_process
Definition: The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
obsolete epithelial cell proliferation involved in liver morphogenesis (GO:0072575)
Namespace: biological_process
Definition: OBSOLETE. The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
liver morphogenesis (GO:0072576)
Namespace: biological_process
Definition: The process in which the anatomical structures of the liver are generated and organized.
endothelial cell apoptotic process (GO:0072577)
Namespace: biological_process
Definition: Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
Synonyms: apoptosis of endothelial cells; endothelial cell apoptosis; endothelial cell programmed cell death by apoptosis; killing of endothelial cells; programmed cell death of endothelial cells by apoptosis; programmed cell death, endothelial cells
neurotransmitter-gated ion channel clustering (GO:0072578)
Namespace: biological_process
Definition: The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
bacterial-type EF-P lysine modification (GO:0072580)
Namespace: biological_process
Definition: The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
Synonyms: EF-P modification pathway
Comment: The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34.
obsolete protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine (GO:0072581)
Namespace: biological_process
Definition: OBSOLETE. The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
Comment: This term was obsoleted because it represents a molecular function.
17-beta-hydroxysteroid dehydrogenase (NADP+) activity (GO:0072582)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
clathrin-dependent endocytosis (GO:0072583)
Namespace: biological_process
Definition: An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
Synonyms: clathrin coated pit-dependent endocytosis; clathrin-mediated endocytosis; CME
xanthosine nucleotidase activity (GO:0072585)
Namespace: molecular_function
Definition: Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
Synonyms: xanthosine ribohydrolase activity
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity (GO:0072586)
Namespace: molecular_function
Definition: Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity (GO:0072587)
Namespace: molecular_function
Definition: Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
box H/ACA RNP complex (GO:0072588)
Namespace: cellular_component
Definition: A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.
Synonyms: box H/ACA snoRNP pseudouridylase complex; sRNP complex
N-acetyl-L-aspartate-L-glutamate ligase activity (GO:0072590)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
citrate-L-glutamate ligase activity (GO:0072591)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
oxygen metabolic process (GO:0072592)
Namespace: biological_process
Definition: The chemical reactions and pathways involving diatomic oxygen (O2).
Synonyms: diatomic oxygen metabolic process; oxygen metabolism
reactive oxygen species metabolic process (GO:0072593)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
Synonyms: reactive oxygen species metabolism; ROS metabolic process
establishment of protein localization to organelle (GO:0072594)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
Synonyms: establishment of protein localisation to organelle
maintenance of protein localization in organelle (GO:0072595)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
Synonyms: maintenance of protein localisation to organelle; maintenance of protein localization to organelle
protein localization to chloroplast (GO:0072598)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained at, a location in a chloroplast.
Synonyms: protein localisation to chloroplast
establishment of protein localization to endoplasmic reticulum (GO:0072599)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location in the endoplasmic reticulum.
Synonyms: establishment of protein localisation to endoplasmic reticulum; establishment of protein localisation to ER; establishment of protein localization in endoplasmic reticulum; establishment of protein localization to ER
interleukin-28A production (GO:0072627)
Namespace: biological_process
Definition: The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-28A production; IL28A production; interferon lambda 2 production; interleukin-28A secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interleukin-28B production (GO:0072629)
Namespace: biological_process
Definition: The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-28B production; IL28B production; interferon lambda 3 production; interleukin-28B secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interleukin-29 production (GO:0072631)
Namespace: biological_process
Definition: The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-29 production; IL29 production; interferon lambda 1 production; interleukin-29 secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interleukin-30 production (GO:0072633)
Namespace: biological_process
Definition: The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-30 production; interleukin-30 complex production; interleukin-30 secretion
interleukin-31 production (GO:0072635)
Namespace: biological_process
Definition: The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-31 production; interleukin-31 secretion
interleukin-32 production (GO:0072637)
Namespace: biological_process
Definition: The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IL-32 production; IL32 production; interleukin-32 biosynthetic process; interleukin-32 secretion; NK4 production; TAIF production
interleukin-33 production (GO:0072639)
Namespace: biological_process
Definition: The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: C9orf26 production; IL-33 production; IL1F11 production; IL33 production; interleukin-33 biosynthetic process; interleukin-33 secretion; NF-HEV production
interferon-delta production (GO:0072645)
Namespace: biological_process
Definition: The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IFN-delta production; IFND production; interferon-delta secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interferon-kappa production (GO:0072649)
Namespace: biological_process
Definition: The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IFN-kappa production; IFNK production; interferon-kappa secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interferon-tau production (GO:0072651)
Namespace: biological_process
Definition: The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IFN-tau production; IFN-tau secretion; IFNT production; interferon-tau secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
interferon-omega production (GO:0072653)
Namespace: biological_process
Definition: The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: IFN-omega production; IFNW production; interferon-omega secretion
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
obsolete establishment of protein localization to mitochondrion (GO:0072655)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
Synonyms: establishment of protein localisation to mitochondrion; establishment of protein localization in mitochondrion
Comment: The reason for obsoletion is that this term was added in error.
maintenance of protein location in mitochondrion (GO:0072656)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
protein localization to membrane (GO:0072657)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a specific location in a membrane.
Synonyms: protein localisation in membrane; protein localization in membrane
maintenance of protein location in membrane (GO:0072658)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
protein localization to plasma membrane (GO:0072659)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
Synonyms: protein localisation in plasma membrane; protein localization in plasma membrane; protein targeting to plasma membrane; protein-plasma membrane targeting
maintenance of protein location in plasma membrane (GO:0072660)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
protein localization to peroxisome (GO:0072662)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained at, a location in a peroxisome.
Synonyms: protein localisation to peroxisome
establishment of protein localization to peroxisome (GO:0072663)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location in a peroxisome.
Synonyms: establishment of protein localisation to peroxisome
maintenance of protein location in peroxisome (GO:0072664)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.
protein localization to vacuole (GO:0072665)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained at, a location in a vacuole.
Synonyms: protein localisation to vacuole
establishment of protein localization to vacuole (GO:0072666)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location in a vacuole.
Synonyms: establishment of protein localisation to vacuole
maintenance of protein location in vacuole (GO:0072667)
Namespace: biological_process
Definition: Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.
obsolete tubulin complex biogenesis (GO:0072668)
Namespace: biological_process
Definition: OBSOLETE. A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a tubulin complex. Includes the synthesis and folding of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex. A tubulin complex is a heterodimer of tubulins alpha and beta, from which microtubules are assembled.
Synonyms: tubulin complex biogenesis
Comment: This term was obsoleted because biogenesis should only be used for complexes where synthesis of some non-protein component is necessary for assembly.
tRNA-splicing ligase complex (GO:0072669)
Namespace: cellular_component
Definition: A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.
Synonyms: tRNA splicing ligase complex
mitochondrial tRNA threonylcarbamoyladenosine modification (GO:0072670)
Namespace: biological_process
Definition: The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).
Synonyms: mitochondrial tRNA t6A modification
mitochondria-associated ubiquitin-dependent protein catabolic process (GO:0072671)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
Synonyms: MAD; mitochondria-associated protein catabolic process; mitochondria-associated protein degradation; mitochondrion-associated protein catabolic process
neutrophil extravasation (GO:0072672)
Namespace: biological_process
Definition: The migration of a neutrophil from the blood vessels into the surrounding tissue.
lamellipodium morphogenesis (GO:0072673)
Namespace: biological_process
Definition: A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.
Synonyms: lamellipodium organization
multinuclear osteoclast differentiation (GO:0072674)
Namespace: biological_process
Definition: The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
Synonyms: multinuclear osteoclast formation; multinuclear osteoclast morphogenesis
osteoclast fusion (GO:0072675)
Namespace: biological_process
Definition: The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.
eosinophil migration (GO:0072677)
Namespace: biological_process
Definition: The movement of an eosinophil within or between different tissues and organs of the body.
T cell migration (GO:0072678)
Namespace: biological_process
Definition: The movement of a T cell within or between different tissues and organs of the body.
Synonyms: T lymphocyte migration; T-cell migration; T-lymphocyte migration
thymocyte migration (GO:0072679)
Namespace: biological_process
Definition: The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.
Synonyms: immature T cell migration; immature T lymphocyte migration; immature T-cell migration; immature T-lymphocyte migration; thymic lymphocyte migration
extracellular matrix-dependent thymocyte migration (GO:0072680)
Namespace: biological_process
Definition: The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.
Synonyms: extracellular matrix-dependent immature T cell migration; extracellular matrix-dependent immature T lymphocyte migration; extracellular matrix-dependent immature T-cell migration; extracellular matrix-dependent immature T-lymphocyte migration; extracellular matrix-dependent thymic lymphocyte migration
fibronectin-dependent thymocyte migration (GO:0072681)
Namespace: biological_process
Definition: The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.
Synonyms: fibronectin-dependent immature T cell migration; fibronectin-dependent immature T lymphocyte migration; fibronectin-dependent immature T-cell migration; fibronectin-dependent immature T-lymphocyte migration; fibronectin-dependent thymic lymphocyte migration
eosinophil extravasation (GO:0072682)
Namespace: biological_process
Definition: The migration of an eosinophil from the blood vessels into the surrounding tissue.
T cell extravasation (GO:0072683)
Namespace: biological_process
Definition: The migration of a T cell from the blood vessels into the surrounding tissue.
Synonyms: T lymphocyte extravasation; T-cell extravasation; T-lymphocyte extravasation
obsolete mitochondrial tRNA 3'-trailer cleavage, endonucleolytic (GO:0072684)
Namespace: biological_process
Definition: OBSOLETE. Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.
Synonyms: mitochondrial endonucleolytic tRNA 3'-end cleavage; mitochondrial endonucleolytic tRNA 3'-trailer cleavage; mitochondrial tRNA 3'-end cleavage, endonucleolytic
Comment: he reason for obsoletion is that these term represent molecular functions.
Mre11 complex assembly (GO:0072685)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.
Synonyms: MRN complex assembly; MRX complex assembly; Rad50 complex assembly; RAD50-MRE11-NBN complex assembly; Rad50-Rad32-Nbs1 complex assembly; RMX complex assembly
mitotic spindle (GO:0072686)
Namespace: cellular_component
Definition: A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
meiotic spindle (GO:0072687)
Namespace: cellular_component
Definition: A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
SHREC complex localization (GO:0072688)
Namespace: biological_process
Definition: Any process in which a SHREC complex is transported to, or maintained in, a specific location.
Synonyms: establishment and maintenance of SHREC complex localization; SHREC complex localisation