LiteFold/GO huggingface dataset:
positive regulation of compound eye pigmentation (GO:0048078)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
Synonyms: activation of eye pigmentation; positive regulation of eye pigmentation; stimulation of eye pigmentation; up regulation of eye pigmentation; up-regulation of eye pigmentation; upregulation of eye pigmentation
regulation of cuticle pigmentation (GO:0048079)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
negative regulation of cuticle pigmentation (GO:0048080)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
Synonyms: down regulation of cuticle pigmentation; down-regulation of cuticle pigmentation; downregulation of cuticle pigmentation; inhibition of cuticle pigmentation
positive regulation of cuticle pigmentation (GO:0048081)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
Synonyms: activation of cuticle pigmentation; stimulation of cuticle pigmentation; up regulation of cuticle pigmentation; up-regulation of cuticle pigmentation; upregulation of cuticle pigmentation
regulation of adult chitin-containing cuticle pigmentation (GO:0048082)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
negative regulation of adult chitin-containing cuticle pigmentation (GO:0048083)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
Synonyms: down regulation of adult chitin-containing cuticle pigmentation; down-regulation of adult chitin-containing cuticle pigmentation; downregulation of adult chitin-containing cuticle pigmentation; inhibition of adult chitin-containing cuticle pigmentation
positive regulation of adult chitin-containing cuticle pigmentation (GO:0048084)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
Synonyms: activation of adult chitin-containing cuticle pigmentation; stimulation of adult chitin-containing cuticle pigmentation; up regulation of adult chitin-containing cuticle pigmentation; up-regulation of adult chitin-containing cuticle pigmentation; upregulation of adult chitin-containing cuticle pigmentation
adult chitin-containing cuticle pigmentation (GO:0048085)
Namespace: biological_process
Definition: Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.
Synonyms: adult cuticle pigmentation
negative regulation of developmental pigmentation (GO:0048086)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
Synonyms: down regulation of developmental pigmentation; down-regulation of developmental pigmentation; downregulation of developmental pigmentation; inhibition of pigmentation
positive regulation of developmental pigmentation (GO:0048087)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
Synonyms: activation of developmental pigmentation; stimulation of developmental pigmentation; up regulation of developmental pigmentation; up-regulation of developmental pigmentation; upregulation of developmental pigmentation
regulation of male pigmentation (GO:0048088)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.
regulation of female pigmentation (GO:0048089)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.
negative regulation of female pigmentation (GO:0048090)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.
Synonyms: down regulation of female pigmentation; down-regulation of female pigmentation; downregulation of female pigmentation; inhibition of female pigmentation
positive regulation of female pigmentation (GO:0048091)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.
Synonyms: activation of female pigmentation; stimulation of female pigmentation; up regulation of female pigmentation; up-regulation of female pigmentation; upregulation of female pigmentation
negative regulation of male pigmentation (GO:0048092)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.
Synonyms: down regulation of male pigmentation; down-regulation of male pigmentation; downregulation of male pigmentation; inhibition of male pigmentation
male pigmentation (GO:0048094)
Namespace: biological_process
Definition: Establishment of a pattern of pigment in males.
obsolete long-term maintenance of gene activation (GO:0048097)
Namespace: biological_process
Definition: OBSOLETE. Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term.
Comment: This term has been obsoleted because its definition was not clear, and had no references and no annotations.
antennal joint development (GO:0048098)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.
anterior/posterior lineage restriction, imaginal disc (GO:0048099)
Namespace: biological_process
Definition: Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.
wing disc anterior/posterior pattern formation (GO:0048100)
Namespace: biological_process
Definition: The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
autophagic cell death (GO:0048102)
Namespace: biological_process
Definition: A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
Synonyms: autophagic death; autosis; programmed cell death by autophagy; programmed cell death by macroautophagy; type II programmed cell death
Comment: The precise nature of autophagic cell death is still being debated, and the link between autophagy and cell death unclear. As autophagy is often induced under conditions of stress that could also lead to cell death, there has been a propagation of the idea that autophagy can act as a cell death mechanism; but others suggest that autophagy may simply be an attempt of dying cells to adapt to lethal stress rather than a mechanism to execute a cell death program. Further studies are required to resolve this controversy (see e.g. PMID:22082964, PMID:22052193, PMID:25236395). In the meantime, curators should carefully examine the experimental evidence presented in papers concerning autophagic cell death, and annotate accordingly. Recently, an instance of autophagic cell death, termed autosis, was discovered that relies on the plasma membrane Na+/K+-ATPase. Autosis was observed in vivo in the brain of rats subjected to an ischemic insult. It's still unclear if all cases of autophagic cell death require the Na+/K+-ATPase or not.
somatic stem cell division (GO:0048103)
Namespace: biological_process
Definition: The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
Synonyms: somatic stem cell renewal
establishment of body hair or bristle planar orientation (GO:0048104)
Namespace: biological_process
Definition: Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.
establishment of thoracic bristle planar orientation (GO:0048106)
Namespace: biological_process
Definition: Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.
Synonyms: establishment of body bristle planar orientation
4-amino-3-isothiazolidinone biosynthetic process (GO:0048107)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.
Synonyms: 4-amino-3-isothiazolidinone anabolism; 4-amino-3-isothiazolidinone biosynthesis; 4-amino-3-isothiazolidinone formation; 4-amino-3-isothiazolidinone synthesis
obsolete peptide cross-linking via 4-amino-3-isothiazolidinone (GO:0048108)
Namespace: biological_process
Definition: OBSOLETE. The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.
Comment: This term was obsoleted because it represents a non-entymatic protein modification, see PMID:12802338.
female germ-line stem cell asymmetric division (GO:0048132)
Namespace: biological_process
Definition: The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
Synonyms: female germ-line stem cell renewal
male germ-line stem cell asymmetric division (GO:0048133)
Namespace: biological_process
Definition: The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
Synonyms: male germ-line stem cell renewal
germ-line cyst formation (GO:0048134)
Namespace: biological_process
Definition: Formation of a group of interconnected cells derived from a single gonial founder cell.
Synonyms: germline cyst formation
female germ-line cyst formation (GO:0048135)
Namespace: biological_process
Definition: Formation of a group of interconnected cells derived from a single female gonial founder cell.
Synonyms: female germline cyst formation
male germ-line cyst formation (GO:0048136)
Namespace: biological_process
Definition: Formation of a group of interconnected cells derived from a single male gonial founder cell.
Synonyms: male germline cyst formation
spermatocyte division (GO:0048137)
Namespace: biological_process
Definition: The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.
Synonyms: spermatocyte cell division
germ-line cyst encapsulation (GO:0048138)
Namespace: biological_process
Definition: Formation of a single follicular epithelium around the germ-line derived cells of a cyst.
male germ-line cyst encapsulation (GO:0048140)
Namespace: biological_process
Definition: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.
germarium-derived cystoblast division (GO:0048142)
Namespace: biological_process
Definition: The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.
Synonyms: germarium-derived cystoblast cell division
astrocyte activation (GO:0048143)
Namespace: biological_process
Definition: A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
fibroblast proliferation (GO:0048144)
Namespace: biological_process
Definition: The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
positive regulation of fibroblast proliferation (GO:0048146)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
Synonyms: activation of fibroblast proliferation; stimulation of fibroblast proliferation; up regulation of fibroblast proliferation; up-regulation of fibroblast proliferation; upregulation of fibroblast proliferation
negative regulation of fibroblast proliferation (GO:0048147)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
Synonyms: down regulation of fibroblast proliferation; down-regulation of fibroblast proliferation; downregulation of fibroblast proliferation; inhibition of fibroblast proliferation
behavioral response to cocaine (GO:0048148)
Namespace: biological_process
Definition: Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
Synonyms: behavioural response to cocaine
behavioral response to ethanol (GO:0048149)
Namespace: biological_process
Definition: Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
Synonyms: behavioural response to ethanol
behavioral response to ether (GO:0048150)
Namespace: biological_process
Definition: Any process that results in a change in the behavior of an organism as a result of an ether stimulus.
Synonyms: behavioural response to ether
obsolete S100 beta biosynthetic process (GO:0048152)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
Synonyms: S100 beta anabolism; S100 beta biosynthesis; S100 beta formation; S100 beta synthesis
Comment: The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.
obsolete S100 alpha biosynthetic process (GO:0048153)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
Synonyms: S100 alpha anabolism; S100 alpha biosynthesis; S100 alpha formation; S100 alpha synthesis
Comment: The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.
tau protein binding (GO:0048156)
Namespace: molecular_function
Definition: Binding to tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
oogonium stage (GO:0048158)
Namespace: biological_process
Definition: The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.
Synonyms: mammalian oogenesis stage 1
primary oocyte stage (GO:0048159)
Namespace: biological_process
Definition: The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.
Synonyms: mammalian oogenesis stage 2
primary follicle stage (GO:0048160)
Namespace: biological_process
Definition: The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
Synonyms: mammalian oogenesis stage 3
double layer follicle stage (GO:0048161)
Namespace: biological_process
Definition: The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.
Synonyms: mammalian oogenesis stage 4
multi-layer follicle stage (GO:0048162)
Namespace: biological_process
Definition: The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.
Synonyms: mammalian oogenesis stage 5
scattered antral spaces stage (GO:0048163)
Namespace: biological_process
Definition: The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.
Synonyms: mammalian oogenesis stage 6
distinct antral spaces stage (GO:0048164)
Namespace: biological_process
Definition: The stage in oogenesis when the antral spaces become distinct and the first polar body forms.
Synonyms: mammalian oogenesis stage 7
fused antrum stage (GO:0048165)
Namespace: biological_process
Definition: The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.
Synonyms: mammalian oogenesis stage 8
regulation of synaptic plasticity (GO:0048167)
Namespace: biological_process
Definition: A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
regulation of neuronal synaptic plasticity (GO:0048168)
Namespace: biological_process
Definition: A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
regulation of long-term neuronal synaptic plasticity (GO:0048169)
Namespace: biological_process
Definition: A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
positive regulation of long-term neuronal synaptic plasticity (GO:0048170)
Namespace: biological_process
Definition: A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
Synonyms: activation of long-term neuronal synaptic plasticity; stimulation of long-term neuronal synaptic plasticity; up regulation of long-term neuronal synaptic plasticity; up-regulation of long-term neuronal synaptic plasticity; upregulation of long-term neuronal synaptic plasticity
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
negative regulation of long-term neuronal synaptic plasticity (GO:0048171)
Namespace: biological_process
Definition: A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
Synonyms: down regulation of long-term neuronal synaptic plasticity; down-regulation of long-term neuronal synaptic plasticity; downregulation of long-term neuronal synaptic plasticity; inhibition of long-term neuronal synaptic plasticity
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
regulation of short-term neuronal synaptic plasticity (GO:0048172)
Namespace: biological_process
Definition: A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
positive regulation of short-term neuronal synaptic plasticity (GO:0048173)
Namespace: biological_process
Definition: A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
Synonyms: activation of short-term neuronal synaptic plasticity; stimulation of short-term neuronal synaptic plasticity; up regulation of short-term neuronal synaptic plasticity; up-regulation of short-term neuronal synaptic plasticity; upregulation of short-term neuronal synaptic plasticity
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
negative regulation of short-term neuronal synaptic plasticity (GO:0048174)
Namespace: biological_process
Definition: A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
Synonyms: down regulation of short-term neuronal synaptic plasticity; down-regulation of short-term neuronal synaptic plasticity; downregulation of short-term neuronal synaptic plasticity; inhibition of short-term neuronal synaptic plasticity
Comment: Note that the syntax of the definition of this term is different from the usual regulation syntax because it describes regulation of a trait rather than regulation of a process.
activin receptor complex (GO:0048179)
Namespace: cellular_component
Definition: A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.