LiteFold/GO huggingface dataset:
thiamine binding (GO:0030975)
Namespace: molecular_function
Definition: Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
Synonyms: thiamin binding; vitamin B1 binding
thiamine pyrophosphate binding (GO:0030976)
Namespace: molecular_function
Definition: Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
Synonyms: aneurine pyrophosphate binding; cocarboxylase binding; diphosphothiamin binding; thiamin pyrophosphate binding; TPP binding
taurine binding (GO:0030977)
Namespace: molecular_function
Definition: Binding to taurine.
alpha-glucan metabolic process (GO:0030978)
Namespace: biological_process
Definition: The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
Synonyms: alpha-glucan metabolism
alpha-glucan biosynthetic process (GO:0030979)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
Synonyms: alpha-glucan anabolism; alpha-glucan biosynthesis; alpha-glucan formation; alpha-glucan synthesis
cortical microtubule cytoskeleton (GO:0030981)
Namespace: cellular_component
Definition: The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.
adventurous gliding motility (GO:0030982)
Namespace: biological_process
Definition: A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.
Synonyms: adventurous gliding movement
mismatched DNA binding (GO:0030983)
Namespace: molecular_function
Definition: Binding to a double-stranded DNA region containing one or more mismatches.
Synonyms: mispair binding; mispaired DNA binding
kininogen binding (GO:0030984)
Namespace: molecular_function
Definition: Binding to a kininogen, a kinin precursor.
low molecular weight kininogen binding (GO:0030986)
Namespace: molecular_function
Definition: Binding to a kininogen of low molecular mass.
Synonyms: LK binding; LMW kininogen binding
high molecular weight kininogen receptor binding (GO:0030987)
Namespace: molecular_function
Definition: Binding to a high molecular weight kininogen receptor.
high molecular weight kininogen receptor complex (GO:0030988)
Namespace: cellular_component
Definition: A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.
dynein-driven meiotic oscillatory nuclear movement (GO:0030989)
Namespace: biological_process
Definition: Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.
Synonyms: HNM; horsetail movement; horsetail nuclear movement
Comment: Dynein-driven meiotic oscillatory nuclear movement precedes meiotic recombination.
intraciliary transport particle (GO:0030990)
Namespace: cellular_component
Definition: A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
Synonyms: IFT complex; intraflagellar transport complex; intraflagellar transport particle
Comment: Note that we deem cilia and microtubule-based flagella to be equivalent.
intraciliary transport particle A (GO:0030991)
Namespace: cellular_component
Definition: The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
Synonyms: IFT A complex; IFT complex A; intraflagellar transport complex A; intraflagellar transport particle A
Comment: Note that we deem cilia and microtubule-based flagella to be equivalent.
intraciliary transport particle B (GO:0030992)
Namespace: cellular_component
Definition: The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
Synonyms: IFT B complex; IFT complex B; intraflagellar transport complex B; intraflagellar transport particle B
Comment: Note that we deem cilia and microtubule-based flagella to be equivalent.
axonemal heterotrimeric kinesin-II complex (GO:0030993)
Namespace: cellular_component
Definition: A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.
primary cell septum disassembly (GO:0030994)
Namespace: biological_process
Definition: Dissolution of the primary septum during cell separation.
Synonyms: hydrolysis of primary cell septum; primary cell septum hydrolysis; primary septum hydrolysis
cell septum edging catabolic process (GO:0030995)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.
Synonyms: cell septum edging hydrolysis; hydrolysis of cell septum edging; hydrolysis of edging of cell septum; septum edging hydrolysis
obsolete mitotic cell cycle arrest in response to nitrogen starvation (GO:0030996)
Namespace: biological_process
Definition: OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of nitrogen.
Synonyms: cell cycle arrest in response to nitrogen starvation
Comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G1 cell cycle arrest in response to nitrogen starvation' has been observed.
regulation of centriole-centriole cohesion (GO:0030997)
Namespace: biological_process
Definition: Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.
linear element (GO:0030998)
Namespace: cellular_component
Definition: A proteinaceous scaffold associated with fission yeast chromosomes during meiotic prophase. Linear elements consist of a protein complex, LinE, with four main structural components (Rec10, Rec25, Rec27, and Mug20 in S. pombe) associated with chromatin. The resulting structure is related to but not equivalent to the synaptonemal complex.
linear element assembly (GO:0030999)
Namespace: biological_process
Definition: The cell cycle process in which linear elements are assembled in association with fission yeast chromosomes during meiotic prophase. Linear element assembly begins with LinE complex formation and ends when LinE complexes are associated with chromatin in structures visible as nuclear foci. A linear element is a proteinaceous scaffold related to the synaptonemal complex.
Synonyms: linear element formation
response to caffeine (GO:0031000)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
response to brefeldin A (GO:0031001)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.
actin rod (GO:0031002)
Namespace: cellular_component
Definition: A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Actin rod structures are found in diverse organisms, having been observed in spores of Dictyostelium discoideum, Drosophila melanogaster oocytes, as well as in numerous animal cells under stress conditions.
actin tubule (GO:0031003)
Namespace: cellular_component
Definition: A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.
filamin binding (GO:0031005)
Namespace: molecular_function
Definition: Binding to a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
Synonyms: ABP-278/276 binding; ABP-280 binding; ABPL binding; alpha-filamin binding; beta-filamin binding; filamin A binding; filamin B binding; filamin C binding; filamin-1 binding; filamin-2 binding; filamin-3 binding; filamin-A binding; filamin-B binding; filamin-C binding; gamma-filamin binding
plastid ADPG pyrophosphorylase complex (GO:0031009)
Namespace: cellular_component
Definition: An ADPG pyrophosphorylase complex found in a plastid.
ISWI-type complex (GO:0031010)
Namespace: cellular_component
Definition: Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.
Ino80 complex (GO:0031011)
Namespace: cellular_component
Definition: A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.
Synonyms: INO80 chromatin remodeling complex
extracellular matrix (GO:0031012)
Namespace: cellular_component
Definition: A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
Synonyms: matrisome; proteinaceous extracellular matrix
troponin I binding (GO:0031013)
Namespace: molecular_function
Definition: Binding to troponin I, the inhibitory subunit of the troponin complex.
troponin T binding (GO:0031014)
Namespace: molecular_function
Definition: Binding to troponin T, the tropomyosin-binding subunit of the troponin complex.
obsolete karyopherin docking complex (GO:0031015)
Namespace: cellular_component
Definition: OBSOLETE. A subcomplex of the nuclear pore complex that interacts with karyopherin-cargo complexes; a well-characterized example in Saccharomyces contains Asm4p, Nup53p, and Nup170p.
Synonyms: Asm4p-containing complex; karyopherin docking complex; nuclear pore subcomplex
pancreas development (GO:0031016)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones.
exocrine pancreas development (GO:0031017)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
endocrine pancreas development (GO:0031018)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
mitochondrial mRNA editing complex (GO:0031019)
Namespace: cellular_component
Definition: An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
Synonyms: mitochondrial editosome
plastid mRNA editing complex (GO:0031020)
Namespace: cellular_component
Definition: An mRNA editing complex found in a plastid.
Synonyms: plastid editosome
interphase microtubule organizing center (GO:0031021)
Namespace: cellular_component
Definition: A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.
Synonyms: iMTOC; interphase microtubule organising center; interphase MTOC
nuclear migration along microfilament (GO:0031022)
Namespace: biological_process
Definition: The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.
Synonyms: nuclear migration, microfilament-mediated
microtubule organizing center organization (GO:0031023)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
Synonyms: microtubule organising center organisation; microtubule organizing center organization and biogenesis
interphase microtubule organizing center assembly (GO:0031024)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.
Synonyms: interphase microtubule organising center biosynthesis; interphase microtubule organising center formation; interphase microtubule organizing center biogenesis; interphase microtubule organizing centre assembly
equatorial microtubule organizing center disassembly (GO:0031025)
Namespace: biological_process
Definition: The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.
Synonyms: equatorial microtubule organising center disassembly
glutamate synthase complex (GO:0031026)
Namespace: cellular_component
Definition: A complex that possesses glutamate synthase activity.
glutamate synthase complex (NADH) (GO:0031027)
Namespace: cellular_component
Definition: A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.
septation initiation signaling (GO:0031028)
Namespace: biological_process
Definition: The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.
Synonyms: septation initiation network; septation initiation signaling cascade; septation initiation signalling; SIN
regulation of septation initiation signaling (GO:0031029)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of septation initiation signaling.
Synonyms: regulation of septation initiation network; regulation of septation initiation signaling cascade; regulation of septation initiation signalling
negative regulation of septation initiation signaling (GO:0031030)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.
Synonyms: down regulation of septation initiation signaling; down-regulation of septation initiation signaling; downregulation of septation initiation signaling; inhibition of septation initiation signaling; negative regulation of septation initiation network; negative regulation of septation initiation signaling cascade; negative regulation of septation initiation signalling
positive regulation of septation initiation signaling (GO:0031031)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of septation initiation signaling.
Synonyms: activation of septation initiation signaling; positive regulation of septation initiation network; positive regulation of septation initiation signaling cascade; positive regulation of septation initiation signalling; stimulation of septation initiation signaling; up regulation of septation initiation signaling; up-regulation of septation initiation signaling; upregulation of septation initiation signaling
actomyosin structure organization (GO:0031032)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.
Synonyms: actomyosin organization; actomyosin structure organisation; actomyosin structure organization and biogenesis
Comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins.
myosin filament organization (GO:0031033)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.
Synonyms: myosin filament assembly or disassembly; myosin filament organisation; myosin polymerization or depolymerization
Comment: Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins; myosin structures are sufficiently closely associated with actin filaments to be included with the actin cytoskeleton.
myosin filament assembly (GO:0031034)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a filament composed of myosin molecules.
Synonyms: myosin polymerization
myosin filament disassembly (GO:0031035)
Namespace: biological_process
Definition: The disassembly of a filament composed of myosin molecules.
Synonyms: myosin depolymerization
myosin II filament assembly (GO:0031036)
Namespace: biological_process
Definition: The formation of a bipolar filament composed of myosin II molecules.
Synonyms: myosin II polymerization
myosin II filament disassembly (GO:0031037)
Namespace: biological_process
Definition: The disassembly of a bipolar filament composed of myosin II molecules.
Synonyms: myosin II depolymerization
myosin II filament organization (GO:0031038)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
Synonyms: myosin II filament assembly or disassembly; myosin II filament organisation; myosin II polymerization or depolymerization
macronucleus (GO:0031039)
Namespace: cellular_component
Definition: A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.
micronucleus (GO:0031040)
Namespace: cellular_component
Definition: A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.
obsolete O-glycan processing, core 5 (GO:0031041)
Namespace: biological_process
Definition: OBSOLETE. The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.
Comment: This term was obsoleted because it represents a molecular function.
obsolete O-glycan processing, core 6 (GO:0031042)
Namespace: biological_process
Definition: OBSOLETE. The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.
Comment: This term was obsoleted because it represents a molecular function.
obsolete O-glycan processing, core 7 (GO:0031043)
Namespace: biological_process
Definition: OBSOLETE. The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.
Comment: This term was obsoleted because it represents a molecular function.
obsolete O-glycan processing, core 8 (GO:0031044)
Namespace: biological_process
Definition: OBSOLETE. The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.
Comment: This term was obsoleted because it represents a molecular function.
dense core granule (GO:0031045)
Namespace: cellular_component
Definition: Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
Synonyms: dense core vesicle
regulatory ncRNA-mediated gene silencing (GO:0031047)
Namespace: biological_process
Definition: A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.
Synonyms: gene silencing by RNA; RNA-dependent gene silencing; RNA-mediated gene silencing
regulatory ncRNA-mediated heterochromatin formation (GO:0031048)
Namespace: biological_process
Definition: A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginning of trancription.
Synonyms: chromatin silencing by small RNA; heterochromatin assembly by small RNA; heterochromatin assembly involved in chromatin silencing by small RNA; heterochromatin formation involved in chromatin silencing by small RNA; ncRNA-mediated heterochromatin formation; pre-transcriptional gene silencing by RNA; pre-transcriptional gene silencing by small non-coding RNA; RNA interference-like chromatin silencing; RNA-dependent heterochromatin formation; RNA-mediated chromatin silencing; RNA-mediated heterochromatin formation; RNA-mediated TGS; RNA-mediated transcriptional silencing; RNAi-directed chromatin silencing; RNAi-like chromatin silencing; small ncRNA-mediated heterochromatin formation; small non-coding RNA-dependent heterochromatin formation; small RNA-mediated heterochromatic silencing; small RNA-mediated heterochromatin formation
programmed DNA elimination (GO:0031049)
Namespace: biological_process
Definition: A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.
programmed DNA elimination by chromosome breakage (GO:0031052)
Namespace: biological_process
Definition: Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
Synonyms: chromosome breakage
Comment: Note that this term refers to breakage of chromosomes during normal DNA well characterized in ciliates but also present in many vertebrates; it is not to be used for DNA damage or other abnormal occurrences.