LiteFold/GO huggingface dataset:
obsolete viral entry into host cell via pilus retraction (GO:0039667)
Namespace: biological_process
Definition: OBSOLETE. The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus.
Comment: This term was obsoleted because it represents the same process as virion attachment to host cell pilus ; GO:0039666.
obsolete viral entry into host cell via pilus basal pore (GO:0039668)
Namespace: biological_process
Definition: OBSOLETE. The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way.
Synonyms: filamentous viral entry into host cell via pilus retraction
Comment: This term was obsoleted because it represents the same process as virion attachment to host cell pilus ; GO:0039666.
obsolete viral entry into host cell via pilus retraction and membrane fusion (GO:0039669)
Namespace: biological_process
Definition: OBSOLETE. The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane.
Comment: This term was obsoleted because it represents the same process as virion attachment to host cell pilus ; GO:0039666.
viral capsid, turret (GO:0039670)
Namespace: cellular_component
Definition: A turret-like appendage formed at the vertices of an icosahedral capsid.
symbiont-mediated perturbation of host natural killer cell mediated immune response (GO:0039671)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts the natural killer cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: evasion by virus of host natural killer cell activity; evasion by virus of host natural killer cell response; evasion by virus of host NK cell killing; modulation of host NK-cell activity by virus; protection by virus against host NK cell cytotoxicity; suppression by virus of host natural killer cell function; viral immunoevasion of host NK cell
symbiont-mediated suppression of host dendritic cell mediated immune response (GO:0039673)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the dendritic cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: evasion by virus of host dendritic cell activity; evasion by virus of host dendritic cell response; impairing dendritic cell function by virus; modulation of host dendritic cell activity by virus
exit of virus from host cell nucleus (GO:0039674)
Namespace: biological_process
Definition: The directed movement of the viral genome or a viral particle out of the host cell nucleus.
exit of virus from host cell nucleus through nuclear pore (GO:0039675)
Namespace: biological_process
Definition: The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.
Synonyms: exit of virus from host cell nucleus through nuclear pore complex; nuclear pore exit of virus; viral enome export through nuclear pore
exit of virus from host cell nucleus via nuclear envelope disassembly (GO:0039677)
Namespace: biological_process
Definition: The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.
Synonyms: exit of virus from host cell nucleus via nuclear envelope breakdown
symbiont genome ejection through host cell envelope (GO:0039678)
Namespace: biological_process
Definition: Entry of a symbiont's genome into the host cell through the host cell envelope. Occurs in non-enveloped prokaryotic viruses. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.
Synonyms: phage genome ejection; viral genome ejection through host cell envelope; viral genome injection through bacterial membranes
actin-dependent intracellular transport of virus towards nucleus (GO:0039680)
Namespace: biological_process
Definition: The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.
Synonyms: actin-dependent intracellular transport of viral material towards nucleus; actin-dependent inwards viral transport
rolling circle double-stranded viral DNA replication (GO:0039683)
Namespace: biological_process
Definition: A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.
Synonyms: dsDNA rolling circle replication
rolling circle single-stranded viral DNA replication (GO:0039684)
Namespace: biological_process
Definition: A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.
Synonyms: ssDNA rolling circle replication
rolling hairpin viral DNA replication (GO:0039685)
Namespace: biological_process
Definition: A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.
Synonyms: ssDNA rolling hairpin viral DNA replication
bidirectional double-stranded viral DNA replication (GO:0039686)
Namespace: biological_process
Definition: A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.
Synonyms: viral bidirectional dsDNA replication
viral DNA strand displacement replication (GO:0039687)
Namespace: biological_process
Definition: A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).
viral double stranded DNA replication via reverse transcription (GO:0039688)
Namespace: biological_process
Definition: A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.
Synonyms: dsDNA replication via RNA intermediate; RNA-dependent viral DNA replication; viral RNA-dependent DNA replication
negative stranded viral RNA replication (GO:0039689)
Namespace: biological_process
Definition: A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).
Synonyms: (-)ss viral RNA replication
positive stranded viral RNA replication (GO:0039690)
Namespace: biological_process
Definition: A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.
Synonyms: ss(+) viral RNA replication
double stranded viral RNA replication (GO:0039691)
Namespace: biological_process
Definition: A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.
single stranded viral RNA replication via double stranded DNA intermediate (GO:0039692)
Namespace: biological_process
Definition: A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.
Synonyms: retroviral genome replication; viral ssRNA replication via dsDNA intermediate
viral DNA genome replication (GO:0039693)
Namespace: biological_process
Definition: The replication of a viral DNA genome.
Synonyms: DNA-dependent viral DNA replication; viral DNA replication; viral DNA-dependent DNA replication
viral RNA genome replication (GO:0039694)
Namespace: biological_process
Definition: The replication of a viral RNA genome.
negative stranded viral RNA transcription (GO:0039697)
Namespace: biological_process
Definition: A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.
fusion of viral membrane with host outer nuclear membrane (GO:0039700)
Namespace: biological_process
Definition: Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.
Synonyms: fusion of viral membrane with host outer nuclear membrane involved in nuclear egress; viral primary envelope fusion with host outer nuclear membrane
microtubule-dependent intracellular transport of viral material towards cell periphery (GO:0039701)
Namespace: biological_process
Definition: The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.
viral budding via host ESCRT complex (GO:0039702)
Namespace: biological_process
Definition: Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.
Synonyms: host-assisted viral budding; viral budding through the ESCRT machinery
RNA replication (GO:0039703)
Namespace: biological_process
Definition: The cellular metabolic process in which a cell duplicates one or more molecules of RNA.
viral translational shunt (GO:0039704)
Namespace: biological_process
Definition: A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.
Synonyms: ribosomal shunt initiation pathway
Comment: This term is intended to annotate gene products involved in the process of viral translational shunt, not viral proteins produced by this translation process.
viral translational readthrough (GO:0039705)
Namespace: biological_process
Definition: The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.
Synonyms: viral RNA suppression of termination; viral stop codon readthrough
Comment: This term is intended to annotate gene products involved in the process of viral translational readthrough, not viral proteins produced by this translation process.
co-receptor binding (GO:0039706)
Namespace: molecular_function
Definition: Binding to a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.
obsolete virus-mediated pore formation in host cell membrane (GO:0039707)
Namespace: biological_process
Definition: OBSOLETE. The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.
Synonyms: pore formation by virus in membrane of host cell; pore formation in membrane of host cell by virus; viroporin
Comment: This term represents a taxon-specific version of the same process, symbiont entry into host cell via pore formation in plasma membrane ; GO:0044694.
nuclear capsid assembly (GO:0039708)
Namespace: biological_process
Definition: The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.
cytoplasmic capsid assembly (GO:0039709)
Namespace: biological_process
Definition: The assembly of a virus capsid that occurs in the cytoplasm.
cytoplasmic icosahedral capsid assembly (GO:0039710)
Namespace: biological_process
Definition: The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.
cytoplasmic helical capsid assembly (GO:0039711)
Namespace: biological_process
Definition: The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.
obsolete induction by virus of host catalytic activity (GO:0039712)
Namespace: biological_process
Definition: OBSOLETE. Any viral process that activates or increases the frequency, rate or extent of host catalytic activity.
Synonyms: induction by virus of host enzyme activity
Comment: This term was obsoleted because it represents a molecular function.
viral factory (GO:0039713)
Namespace: cellular_component
Definition: An intracellular compartment in a host cell which increases the efficiency of viral replication, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.
Synonyms: virus factory
cytoplasmic viral factory (GO:0039714)
Namespace: cellular_component
Definition: A viral factory located in the cytoplasm of a host cell.
nuclear viral factory (GO:0039715)
Namespace: cellular_component
Definition: A viral factory located in the nucleus of a host cell.
viroplasm viral factory (GO:0039716)
Namespace: cellular_component
Definition: A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.
tube viral factory (GO:0039719)
Namespace: cellular_component
Definition: A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.
virogenic stroma (GO:0039720)
Namespace: cellular_component
Definition: A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.
Synonyms: VS
peristromal region viral factory (GO:0039721)
Namespace: cellular_component
Definition: A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.
Synonyms: PR
symbiont-mediated suppression of host toll-like receptor signaling pathway (GO:0039722)
Namespace: biological_process
Definition: A process in which a symbiont interferes with, inhibits or disrupts a toll-like receptor signaling pathway in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: inhibition of host TLR pathway by virus; suppression by virus of host TLR signaling pathway; suppression by virus of host toll-like receptor signaling pathway
symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity (GO:0039723)
Namespace: biological_process
Definition: Any process in which a symbiont stops, prevents, or reduces a cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.
Synonyms: inhibition of host TBK1 by virus; suppression by virus of host TBK1 activity; suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity; symbiont-mediated suppression of host TKB signaling
Comment: This term is for annotation of symbiont proteins that counteract the host anti-microbial innate immune response.
symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity (GO:0039724)
Namespace: biological_process
Definition: A process in which a symbiont interferes with, inhibits or disrupts a cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).
Synonyms: inhibition of host IKBKE by virus; suppression by virus of host IKBKE activity; suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity
establishment of mitotic spindle localization (GO:0040001)
Namespace: biological_process
Definition: The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
Synonyms: establishment of mitotic spindle localisation; mitotic spindle positioning; mitotic spindle positioning and orientation; mitotic spindle positioning or orientation; spindle positioning during mitosis; spindle positioning involved in mitotic cell cycle
collagen and cuticulin-based cuticle development (GO:0040002)
Namespace: biological_process
Definition: Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.
Synonyms: collagen and cuticulin-based cuticle anabolism; collagen and cuticulin-based cuticle biosynthetic process; collagen and cuticulin-based cuticle formation; collagen and cuticulin-based cuticle synthesis
chitin-based cuticle development (GO:0040003)
Namespace: biological_process
Definition: Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
Synonyms: chitin-based cuticle anabolism; chitin-based cuticle biosynthetic process; chitin-based cuticle formation; chitin-based cuticle synthesis
collagen and cuticulin-based cuticle attachment to epithelium (GO:0040004)
Namespace: biological_process
Definition: Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.
Synonyms: cuticular attachment to epithelium
chitin-based cuticle attachment to epithelium (GO:0040005)
Namespace: biological_process
Definition: Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.
Synonyms: cuticular attachment to epithelium
obsolete protein-based cuticle attachment to epithelium (GO:0040006)
Namespace: biological_process
Definition: OBSOLETE. Attaching of a protein-based cuticle to the epithelium underlying it.
Synonyms: cuticular attachment to epithelium; protein-based cuticle attachment to epithelium
Comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.
growth (GO:0040007)
Namespace: biological_process
Definition: The increase in size or mass of an entire organism, a part of an organism or a cell.
Synonyms: growth pattern; non-developmental growth
Comment: See also the biological process term 'cell growth ; GO:0016049'.
regulation of growth (GO:0040008)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
regulation of growth rate (GO:0040009)
Namespace: biological_process
Definition: Any process that modulates the rate of growth of all or part of an organism.
Comment: Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.
positive regulation of growth rate (GO:0040010)
Namespace: biological_process
Definition: Any process that increases the rate of growth of all or part of an organism.
Synonyms: activation of growth rate; stimulation of growth rate; up regulation of growth rate; up-regulation of growth rate; upregulation of growth rate
Comment: Note that this term and its definition depart from the usual conventions for GO 'regulation' process terms; regulation of rate is not usually distinguished from regulation of extent or frequency, but it makes sense to do so for growth regulation.
locomotion (GO:0040011)
Namespace: biological_process
Definition: Self-propelled movement of a cell or organism from one location to another.
regulation of locomotion (GO:0040012)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
negative regulation of locomotion (GO:0040013)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
Synonyms: down regulation of locomotion; down-regulation of locomotion; downregulation of locomotion; inhibition of locomotion
regulation of multicellular organism growth (GO:0040014)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
Synonyms: regulation of body growth; regulation of body size
negative regulation of multicellular organism growth (GO:0040015)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
Synonyms: negative regulation of body growth; negative regulation of body size
embryonic cleavage (GO:0040016)
Namespace: biological_process
Definition: The first few specialized divisions of an activated animal egg.
positive regulation of locomotion (GO:0040017)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
Synonyms: activation of locomotion; stimulation of locomotion; up regulation of locomotion; up-regulation of locomotion; upregulation of locomotion
positive regulation of multicellular organism growth (GO:0040018)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
Synonyms: positive regulation of body growth; positive regulation of body size
positive regulation of embryonic development (GO:0040019)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of embryonic development.
Synonyms: activation of embryonic development; stimulation of embryonic development; up regulation of embryonic development; up-regulation of embryonic development; upregulation of embryonic development
regulation of meiotic nuclear division (GO:0040020)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
Synonyms: regulation of meiosis
hermaphrodite germ-line sex determination (GO:0040021)
Namespace: biological_process
Definition: The determination of sex and sexual phenotype in the germ line of a hermaphrodite.
feminization of hermaphroditic germ-line (GO:0040022)
Namespace: biological_process
Definition: The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.
dauer larval development (GO:0040024)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
vulval development (GO:0040025)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.