LiteFold/GO huggingface dataset:
glutathione gamma-glutamylcysteinyltransferase activity (GO:0016756)
Namespace: molecular_function
Definition: Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
Synonyms: phytochelatin synthase activity
glycosyltransferase activity (GO:0016757)
Namespace: molecular_function
Definition: Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring glycosyl groups; transferase activity, transferring other glycosyl groups; transglycosidase activity; transglycosylase activity
hexosyltransferase activity (GO:0016758)
Namespace: molecular_function
Definition: Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring hexosyl groups
cellulose synthase activity (GO:0016759)
Namespace: molecular_function
Definition: Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).
Synonyms: cellulose synthetase activity
xyloglucan:xyloglucosyl transferase activity (GO:0016762)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.
Synonyms: endo-xyloglucan transferase activity; endoxyloglucan transferase activity; xyloglucan endotransglucosylase activity; xyloglucan:xyloglucan xyloglucanotransferase activity
pentosyltransferase activity (GO:0016763)
Namespace: molecular_function
Definition: Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring pentosyl groups
obsolete transferase activity, transferring other glycosyl groups (GO:0016764)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a glycosyl group, other than hexosyl or pentosyl, from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring other glycosyl groups
Comment: This term was made obsolete because it was an unnecessary grouping term.
transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765)
Namespace: molecular_function
Definition: Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring alkyl or aryl groups, other than methyl groups
obsolete geranylgeranyl-diphosphate geranylgeranyltransferase activity (GO:0016767)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.
Comment: The reason for obsoletion is that this term is a subreaction of 15-cis-phytoene synthase activity.
spermine synthase activity (GO:0016768)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
Synonyms: S-adenosylmethioninamine:spermidine 3-aminopropyltransferase activity; spermidine aminopropyltransferase activity; spermine synthetase activity
transferase activity, transferring nitrogenous groups (GO:0016769)
Namespace: molecular_function
Definition: Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring other nitrogenous groups
obsolete transferase activity, transferring other nitrogenous groups (GO:0016771)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a nitrogenous group, other than amino, amidino or oxime, from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring other nitrogenous groups
Comment: This term was made obsolete because it was an unnecessary grouping term.
transferase activity, transferring phosphorus-containing groups (GO:0016772)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
Comment: Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides.
phosphotransferase activity, alcohol group as acceptor (GO:0016773)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
phosphotransferase activity, carboxyl group as acceptor (GO:0016774)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).
phosphotransferase activity, nitrogenous group as acceptor (GO:0016775)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).
phosphotransferase activity, phosphate group as acceptor (GO:0016776)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).
diphosphotransferase activity (GO:0016778)
Namespace: molecular_function
Definition: Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).
nucleotidyltransferase activity (GO:0016779)
Namespace: molecular_function
Definition: Catalysis of the transfer of a nucleotidyl group from one compound (donor) to another (acceptor).
phosphotransferase activity, for other substituted phosphate groups (GO:0016780)
Namespace: molecular_function
Definition: Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).
phosphotransferase activity, paired acceptors (GO:0016781)
Namespace: molecular_function
Definition: Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.
transferase activity, transferring sulphur-containing groups (GO:0016782)
Namespace: molecular_function
Definition: Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).
sulfurtransferase activity (GO:0016783)
Namespace: molecular_function
Definition: Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
Synonyms: sulphurtransferase activity
3-mercaptopyruvate sulfurtransferase activity (GO:0016784)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol = [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H+. Note that 2-oxo-3-sulfanylpropanoate is also known as 3-mercaptopyruvate.
Synonyms: 3-mercaptopyruvate sulphurtransferase activity; 3-mercaptopyruvate:cyanide sulfurtransferase activity; beta-mercaptopyruvate sulfurtransferase activity; mercaptopyruvate sulfurtransferase activity
selenotransferase activity (GO:0016785)
Namespace: molecular_function
Definition: Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).
Synonyms: transferase activity, transferring selenium-containing groups
hydrolase activity (GO:0016787)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
hydrolase activity, acting on ester bonds (GO:0016788)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any ester bond.
Synonyms: esterase activity
thiolester hydrolase activity (GO:0016790)
Namespace: molecular_function
Definition: Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
Synonyms: thiolesterase activity
triphosphoric monoester hydrolase activity (GO:0016793)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.
diphosphoric monoester hydrolase activity (GO:0016794)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a diphosphoester, releasing a diphosphate and a free hydroxyl group.
phosphoric triester hydrolase activity (GO:0016795)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a phosphoric triester.
obsolete exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (GO:0016796)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
Synonyms: exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5' phosphomonoesters
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters (GO:0016797)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
Comment: This term was obsoleted because it is an unnecessary grouping term.
hydrolase activity, acting on glycosyl bonds (GO:0016798)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any glycosyl bond.
Synonyms: glycosidase activity; glycosylase; N-glycosylase
trialkylsulfonium hydrolase activity (GO:0016802)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a thioether bond, -S-.
Synonyms: thioether hydrolase activity; trialkylsulphonium hydrolase activity
ether hydrolase activity (GO:0016803)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of an ether bond, -O-.
obsolete prolyl aminopeptidase activity (GO:0016804)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the release of a N-terminal proline from a peptide.
Synonyms: cytosol aminopeptidase V; Pro-X aminopeptidase activity; proline aminopeptidase; proline iminopeptidase activity; prolyl aminopeptidase activity
Comment: This term was made obsolete because it represents a gene product, and the substrate specificity it refers to is not cleanly defined.
dipeptidase activity (GO:0016805)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a dipeptide.
Synonyms: cytosolic dipeptidase activity
obsolete dipeptidyl-peptidase and tripeptidyl-peptidase activity (GO:0016806)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of N-terminal di- or tripeptides from a polypeptide chain.
Synonyms: dipeptidyl-peptidase and tripeptidyl-peptidase activity
Comment: This term was made obsolete because it represents two activities.
cysteine-type carboxypeptidase activity (GO:0016807)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
Synonyms: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (GO:0016812)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines (GO:0016813)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles (GO:0016815)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.
obsolete hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds (GO:0016816)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in substances other than amides, amidines and nitriles.
Synonyms: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in other compounds
Comment: This term was made obsolete because it was an unnecessary grouping term.
hydrolase activity, acting on acid anhydrides (GO:0016817)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any acid anhydride.
Synonyms: hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides (GO:0016819)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.
Synonyms: hydrolase activity, acting on acid anhydrides, in sulphonyl-containing anhydrides
obsolete hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement (GO:0016821)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: hydrolase activity, acting on acid anhydrides, involved in cellular and subcellular movement
Comment: This term was made obsolete because it incorporates process information.
hydrolase activity, acting on carbon-carbon bonds, in ketonic substances (GO:0016823)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.
hydrolase activity, acting on halide bonds (GO:0016824)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any halide bond.
hydrolase activity, acting on phosphorus-nitrogen bonds (GO:0016825)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any phosphorus-nitrogen bond.
hydrolase activity, acting on sulfur-nitrogen bonds (GO:0016826)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any sulfur-nitrogen bond.
Synonyms: hydrolase activity, acting on sulphur-nitrogen bonds
hydrolase activity, acting on carbon-phosphorus bonds (GO:0016827)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of any carbon-phosphorus bond.
lyase activity (GO:0016829)
Namespace: molecular_function
Definition: Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
carbon-carbon lyase activity (GO:0016830)
Namespace: molecular_function
Definition: Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms: other carbon-carbon lyase activity
carboxy-lyase activity (GO:0016831)
Namespace: molecular_function
Definition: Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
Synonyms: decarboxylase activity
aldehyde-lyase activity (GO:0016832)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
Synonyms: aldolase activity
oxo-acid-lyase activity (GO:0016833)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
Synonyms: oxo-acid lyase activity; oxoacid lyase activity
obsolete other carbon-carbon lyase activity (GO:0016834)
Namespace: molecular_function
Definition: OBSOLETE. A grouping term for carbon-carbon lyases that cannot be more accurately categorized.
Synonyms: other carbon-carbon lyase activity
Comment: This term was made obsolete because it was an unnecessary grouping term.
carbon-oxygen lyase activity (GO:0016835)
Namespace: molecular_function
Definition: Catalysis of the breakage of a carbon-oxygen bond.
Synonyms: other carbon-oxygen lyase activity
hydro-lyase activity (GO:0016836)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
carbon-oxygen lyase activity, acting on polysaccharides (GO:0016837)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
carbon-oxygen lyase activity, acting on phosphates (GO:0016838)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
obsolete other carbon-oxygen lyase activity (GO:0016839)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the cleavage of a carbon-oxygen bond. Enzymes with this activity are 'miscellaneous' carbon-oxygen lyases that cannot be grouped into one of the specific subclasses of the carbon-oxygen lyases.
Synonyms: other carbon-oxygen lyase activity
Comment: This term was made obsolete because it was an unnecessary grouping term.
carbon-nitrogen lyase activity (GO:0016840)
Namespace: molecular_function
Definition: Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH4+, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
Synonyms: other carbon-nitrogen lyase activity
ammonia-lyase activity (GO:0016841)
Namespace: molecular_function
Definition: Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
amidine-lyase activity (GO:0016842)
Namespace: molecular_function
Definition: Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.
strictosidine synthase activity (GO:0016844)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3alpha(S)-strictosidine + H2O = secologanin + tryptamine.
Synonyms: 3-alpha(S)-strictosidine tryptamine-lyase (secologanin-forming); 3-alpha(S)-strictosidine tryptamine-lyase activity; STR activity; strictosidine synthetase activity
obsolete other carbon-nitrogen lyase activity (GO:0016845)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the cleavage of a carbon-nitrogen bond. Enzymes with this activity are 'miscellaneous' carbon-nitrogen lyases that cannot be grouped into one of the specific subclasses of the carbon-nitrogen lyases.
Synonyms: other carbon-nitrogen lyase activity
Comment: This term was made obsolete because it was an unnecessary grouping term.
carbon-sulfur lyase activity (GO:0016846)
Namespace: molecular_function
Definition: Catalysis of the elimination of hydrogen sulfide or substituted H2S.
Synonyms: carbon-sulphur lyase activity
carbon-halide lyase activity (GO:0016848)
Namespace: molecular_function
Definition: Catalysis of the breakage of a bond between carbon and any halogen atom.
phosphorus-oxygen lyase activity (GO:0016849)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
magnesium chelatase activity (GO:0016851)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O + Mg2+ + protoporphyrin IX = ADP + 3 H+ + Mg-protoporphyrin IX + phosphate.
Synonyms: magnesium-chelatase activity; magnesium-protoporphyrin chelatase activity; magnesium-protoporphyrin IX chelatase activity; Mg-chelatase activity; Mg-protoporphyrin IX chelatase activity; Mg-protoporphyrin IX magnesio-lyase activity; Mg-protoporphyrin IX magnesium-lyase activity; protoporphyrin IX magnesium-chelatase activity; protoporphyrin IX Mg-chelatase activity
sirohydrochlorin cobaltochelatase activity (GO:0016852)
Namespace: molecular_function
Definition: Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
Synonyms: anaerobic cobalt chelatase activity; cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming); cobaltochelatase; sirohydrochlorin cobalt-lyase activity
isomerase activity (GO:0016853)
Namespace: molecular_function
Definition: Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
Synonyms: other isomerase activity
racemase and epimerase activity (GO:0016854)
Namespace: molecular_function
Definition: Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
Synonyms: racemase and epimerase activity, acting on other compounds
Comment: Note that 'epimerase' refers to the conversion of an epimer into its diastereoisomer, and 'racemase' refers to the interconversion of the two enantiomers of a chiral compound.
racemase and epimerase activity, acting on amino acids and derivatives (GO:0016855)
Namespace: molecular_function
Definition: Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.
racemase and epimerase activity, acting on carbohydrates and derivatives (GO:0016857)
Namespace: molecular_function
Definition: Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.
obsolete racemase and epimerase activity, acting on other compounds (GO:0016858)
Namespace: molecular_function
Definition: OBSOLETE. Racemase and epimerase activity on compounds other than amino acids, hydroxy acids, carbohydrates or their derivatives.
Synonyms: racemase and epimerase activity, acting on other compounds
Comment: This term was made obsolete because it was an unnecessary grouping term.
cis-trans isomerase activity (GO:0016859)
Namespace: molecular_function
Definition: Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
intramolecular oxidoreductase activity (GO:0016860)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.
Synonyms: intramolecular isomerase activity; intramolecular oxidoreductase activity, other intramolecular oxidoreductases