LiteFold/GO huggingface dataset:
cytoplasmic microtubule minus-end (GO:0062194)
Namespace: cellular_component
Definition: A microtubule minus end that is part of a cytoplasmic microtubule.
microtubule bundle maintenance (GO:0062195)
Namespace: biological_process
Definition: The organization process that preserves a microtubule bundle in a stable functional or structural state.
regulation of lysosome size (GO:0062196)
Namespace: biological_process
Definition: Any process that modulates the size of a lysosome.
cellular response to chemical stress (GO:0062197)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.
obsolete rDNA replication pause site heterochromatin (GO:0062198)
Namespace: cellular_component
Definition: OBSOLETE. A region of heterochromatin associated with sites in rDNA repeats where replication forks pause.
Comment: This term was obsoleted because it does not represent a specific cellular component.
RAM/MOR signaling (GO:0062200)
Namespace: biological_process
Definition: An intracellular signaling cascade that starts with the activation of S. cerevisiae Kic1p, which activate Mob2p and Cbk1p. Cbk1p phosphorylates Ace2p, which results in its nuclear translocation, where it regulates transcription of genes involved in polarity and morphogenesis.
Synonyms: MOR signaling pathway; morphogenesis Orb6 network; RAM signaling pathway; RAM/MOR signaling pathway
actin wave (GO:0062201)
Namespace: cellular_component
Definition: A cellular anatomical entity that is part of the actin cytoskeleton and results in a wave-like propagation of actin networks. It consists of dynamic structures traveling on the ventral (substrate-attached) side of the cell during cell migration, cytokinesis, adhesion and neurogenesis.
Labd-13(16),14-diene-9-ol synthase activity (GO:0062202)
Namespace: molecular_function
Definition: Catalysis of the reaction: peregrinol diphosphate = diphosphate + labd-13(16),14-diene-9-ol.
Viteagnusin D synthase activity (GO:0062203)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + peregrinol diphosphate = diphosphate + viteagnusin D.
(13S)-vitexifolin A synthase activity (GO:0062204)
Namespace: molecular_function
Definition: Catalysis of the reaction:9alpha-copalyl diphosphate + H2O = (13S)-vitexifolin A + diphosphate.
miltiradiene synthase activity (GO:0062205)
Namespace: molecular_function
Definition: Catalysis of the reaction: (+)-copalyl diphosphate = diphosphate + miltiradiene.
Synonyms: multiradiene synthase activity
manoyl oxide synthase activity (GO:0062206)
Namespace: molecular_function
Definition: Catalysis of the reaction: 8-hydroxycopalyl diphosphate = (13R)-manoyl oxide + diphosphate.
regulation of pattern recognition receptor signaling pathway (GO:0062207)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.
positive regulation of pattern recognition receptor signaling pathway (GO:0062208)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of a pattern recognition receptor signaling pathway.
spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination (GO:0062209)
Namespace: biological_process
Definition: Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.
Synonyms: crossover interference; DSB interference; regulation of spatial distribution of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination; regulation of spatial distribution of meiotic DSB formation involved in reciprocal meiotic recombination
shoot regeneration (GO:0062210)
Namespace: biological_process
Definition: The regeneration process by which a damaged or lost shoot regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to produce a new shoot meristem and subsequently a new shoot.
Synonyms: shoot system regeneration
root regeneration (GO:0062211)
Namespace: biological_process
Definition: The the regeneration process by which a damaged or lost root regrows or re-differentiates. This process may occur via de-differentiation and subsequent reprogramming of somatic cells or activation of existing undifferentiated (meristematic) cells to form a new root meristem and subsequently new root.
regulation of mitotic DNA replication initiation from early origin (GO:0062212)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.
Synonyms: regulation of early replication origin firing
peroxynitrite isomerase activity (GO:0062213)
Namespace: molecular_function
Definition: Catalysis of the reaction: peroxynitrite = nitrate.
regulation of somatic muscle development (GO:0062223)
Namespace: biological_process
Definition: Any process that regulates the rate, frequency or extent of somatic muscle development.
positive regulation of somatic muscle development (GO:0062224)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of somatic muscle development.
negative regulation of somatic muscle development (GO:0062225)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of somatic muscle development.
regulation of adult somatic muscle development (GO:0062226)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of adult somatic muscle development.
positive regulation of adult somatic muscle development (GO:0062227)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of adult somatic muscle development.
regulation of larval somatic muscle development (GO:0062229)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of larval somatic muscle development.
positive regulation of larval somatic muscle development (GO:0062231)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of larval somatic muscle development.
prostanoid catabolic process (GO:0062232)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of prostanoids.
F2-isoprostane catabolic process (GO:0062233)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of F2-isoprostane.
platelet activating factor catabolic process (GO:0062234)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of platelet activating factor, 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine.
Synonyms: 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine catabolic process; PAF catabolic process
axonemal basal plate assembly (GO:0062235)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an axonemal basal plate.
Synonyms: axonemal basal plate formation; axoneme basal plate assembly; basal plate assembly
ionocyte differentiation (GO:0062236)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an ionocyte. Ionocytes are specialized epithelial cells that contribute to osmotic homeostasis.
protein localization to postsynapse (GO:0062237)
Namespace: biological_process
Definition: Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell.
Smp focus (GO:0062238)
Namespace: cellular_component
Definition: A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.
Synonyms: Smp dot
heterochromatin-nuclear membrane anchor activity (GO:0062239)
Namespace: molecular_function
Definition: Binding to heterochromatin and the nuclear inner membrane, in order to establish and maintain the heterochromatin location and organization.
Synonyms: heterochromatin-nuclear membrane tether activity; nuclear membrane-heterochromatin anchor activity; nuclear membrane-heterochromatin tether activity
euchromatin-nuclear membrane anchor activity (GO:0062240)
Namespace: molecular_function
Definition: Binding to euchromatin and the nuclear inner membrane, in order to establish and maintain the euchromatin location and organization.
Synonyms: euchromatin-nuclear membrane tether activity; nuclear membrane-euchromatin anchor activity; nuclear membrane-euchromatin tether activity
double strand break-nuclear membrane anchor activity (GO:0062241)
Namespace: molecular_function
Definition: Binding to DNA double strand breaks and the nuclear inner membrane, in order to facilitate DNA repair.
Synonyms: DNA repair factory
double membrane vesicle viral factory membrane (GO:0062242)
Namespace: cellular_component
Definition: One of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
Synonyms: membrane of double membrane vesicle viral factory
double membrane vesicle viral factory outer membrane (GO:0062243)
Namespace: cellular_component
Definition: The outer of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
Synonyms: outer membrane of double membrane vesicle viral factory
double membrane vesicle viral factory lumen (GO:0062244)
Namespace: cellular_component
Definition: The volume surrounded by the inner membrane of a double membrane vesicle viral factory.
Synonyms: lumen of double membrane vesicle viral factory
double membrane vesicle viral factory inner membrane (GO:0062245)
Namespace: cellular_component
Definition: The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory.
Synonyms: inner membrane of double membrane vesicle viral factory
exocytic vesicle lumen (GO:0062246)
Namespace: cellular_component
Definition: The volume enclosed by an exocytic vesicle.
chloroplast vesicle (GO:0062247)
Namespace: cellular_component
Definition: A intracellular vesicle that is part of a chloroplast.
cleistothecium formation (GO:0062248)
Namespace: biological_process
Definition: The process of producing a cleistothecium, a closed sexual fruiting body that contains ascospores in linear asci. Cleistothecia are present in some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
specification of axis polarity (GO:0065001)
Namespace: biological_process
Definition: The pattern specification process in which the polarity of a body or organ axis is established and maintained.
intracellular protein transmembrane transport (GO:0065002)
Namespace: biological_process
Definition: The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
Synonyms: intracellular membrane translocation of a protein; intracellular protein membrane transport; intracellular protein transport across a membrane
Comment: Note that this term is not intended for use in annotating lateral movement within membranes.
protein-containing complex assembly (GO:0065003)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
Synonyms: cellular macromolecule complex assembly; cellular protein complex assembly; cellular protein-containing complex assembly; chaperone activity; macromolecular complex assembly; macromolecule complex assembly; protein complex assembly; protein complex formation
protein-DNA complex assembly (GO:0065004)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.
Synonyms: DNA-protein complex assembly
protein-lipid complex assembly (GO:0065005)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.
biological regulation (GO:0065007)
Namespace: biological_process
Definition: Any process that modulates a measurable attribute of any biological process, quality or function.
Synonyms: regulation
regulation of biological quality (GO:0065008)
Namespace: biological_process
Definition: Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
Synonyms: regulation of biological attribute; regulation of biological characteristic
regulation of molecular function (GO:0065009)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
Synonyms: regulation of a molecular function
extracellular membrane-bounded organelle (GO:0065010)
Namespace: cellular_component
Definition: Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.
Synonyms: extracellular membrane-enclosed organelle
aspartic-type peptidase activity (GO:0070001)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
glutamic-type peptidase activity (GO:0070002)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
threonine-type peptidase activity (GO:0070003)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
cysteine-type exopeptidase activity (GO:0070004)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
cysteine-type aminopeptidase activity (GO:0070005)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
metalloaminopeptidase activity (GO:0070006)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
obsolete glutamic-type endopeptidase activity (GO:0070007)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
Comment: This term was obsoleted because it represents a specific substrate.
serine-type exopeptidase activity (GO:0070008)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
serine-type aminopeptidase activity (GO:0070009)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
oligopeptidase activity (GO:0070012)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.
intracellular organelle lumen (GO:0070013)
Namespace: cellular_component
Definition: An organelle lumen that is part of an intracellular organelle.
sucrase-isomaltase complex (GO:0070014)
Namespace: cellular_component
Definition: A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.
Synonyms: oligo-1,6-glucosidase complex
alphav-beta3 integrin-thrombospondin complex (GO:0070017)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.
Synonyms: ITGAV-ITGB3-THBS1 complex
obsolete transforming growth factor beta type I receptor homodimeric complex (GO:0070018)
Namespace: cellular_component
Definition: OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers.
Synonyms: TGF-beta type I receptor complex; TGF-beta type I receptor dimer; TGFBR1 homodimer; transforming growth factor beta type I receptor complex
Comment: This term was made obsolete because it does not represent a physiological complex.
obsolete transforming growth factor beta type II receptor homodimeric complex (GO:0070019)
Namespace: cellular_component
Definition: OBSOLETE. A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.
Synonyms: TGF-beta type II receptor complex; TGF-beta type II receptor dimer; TGFBR2 homodimer; transforming growth factor beta type II receptor complex
Comment: This term was made obsolete because it does not represent a physiological complex.
obsolete transforming growth factor beta1-type II receptor complex (GO:0070020)
Namespace: cellular_component
Definition: OBSOLETE. A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer.
Synonyms: TGF-beta receptor II-TGF-beta1 complex; TGF-beta1-type II receptor complex
Comment: This term was made obsolete because it does not represent a physiological complex.
obsolete transforming growth factor beta receptor complex (GO:0070022)
Namespace: cellular_component
Definition: OBSOLETE. A homodimeric receptor complex that consists of two TGF-beta receptor monomers.
Synonyms: TGF-beta receptor complex; transforming growth factor beta receptor complex
Comment: This term was made obsolete because it does not represent a physiological complex.
interleukin-12-interleukin-12 receptor complex (GO:0070023)
Namespace: cellular_component
Definition: A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.
Synonyms: IL12-IL12 receptor complex; IL12B-IL12RB1-IL12RB2 complex
CD19-Vav-PIK3R1 complex (GO:0070024)
Namespace: cellular_component
Definition: A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).
Synonyms: CD19-Vav-PI 3-kinase (p85 subunit) complex
carbon monoxide binding (GO:0070025)
Namespace: molecular_function
Definition: Binding to carbon monoxide (CO).
Synonyms: CO binding
carbon monoxide sensor activity (GO:0070027)
Namespace: molecular_function
Definition: Binding to and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).
Synonyms: carbon monoxide sensing activity
obsolete regulation of transcription by carbon monoxide (GO:0070028)
Namespace: biological_process
Definition: OBSOLETE. Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.
Synonyms: regulation of transcription by CO
Comment: This term was obsoleted because it represents a GO-CAM model.
alphav-beta3 integrin-osteopontin complex (GO:0070029)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.
Synonyms: ITGAV-ITGB3-SPP1 complex
alphav-beta1 integrin-osteopontin complex (GO:0070030)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.
Synonyms: ITGAV-ITGB1-SPP1 complex
alphav-beta5 integrin-osteopontin complex (GO:0070031)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.
Synonyms: ITGAV-ITGB5-SPP1 complex
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex (GO:0070033)
Namespace: cellular_component
Definition: A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).
Synonyms: SNARE complex (Vamp2, Snap25, Stx1a, Cplx2); Vamp2-Snap25-Stx1a-Cplx2 complex
telomerase RNA binding (GO:0070034)
Namespace: molecular_function
Definition: Binding to the telomerase RNA template.
Synonyms: TERC binding
obsolete purine NTP-dependent helicase activity (GO:0070035)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
Comment: The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo), therefore this term was an unnecessary grouping term.
obsolete GTP-dependent helicase activity (GO:0070036)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.
Comment: The reason for obsoletion is that helicases only and always use ATP (although under very specific experimental conditions GTP can perhaps be used; this is not the case in vivo).
rRNA (pseudouridine) methyltransferase activity (GO:0070037)
Namespace: molecular_function
Definition: Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
rRNA (pseudouridine-N3-)-methyltransferase activity (GO:0070038)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
rRNA (guanosine-2'-O-ribose)-methyltransferase activity (GO:0070039)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.
Synonyms: rRNA (guanosine-2'-O-)-methyltransferase activity
rRNA (adenine(2503)-C2-)-methyltransferase activity (GO:0070040)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosine2503 in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine2503 in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine.
Synonyms: rRNA (adenine-C2-)-methyltransferase activity