LiteFold/GO huggingface dataset:
obsolete negative regulation of transcription during mitotic cell cycle (GO:0007068)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
Synonyms: down regulation of transcription during mitosis; down-regulation of transcription during mitosis; downregulation of transcription during mitosis; inhibition of transcription during mitosis; mitotic repression of transcription; negative regulation of transcription, mitotic
Comment: The reason for obsoletion is that 'during' should be captured using an annotation extension.
obsolete negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle (GO:0007069)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.
Synonyms: down regulation of transcription from RNA polymerase I promoter during mitosis; down-regulation of transcription from RNA polymerase I promoter during mitosis; downregulation of transcription from RNA polymerase I promoter during mitosis; inhibition of transcription from RNA polymerase I promoter during mitosis; mitotic repression of transcription from Pol I promoter; negative regulation of transcription from Pol I promoter during mitosis; negative regulation of transcription from RNA polymerase I promoter, mitotic
Comment: The reason for obsoletion is that 'during' should be captured using an annotation extension.
obsolete negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle (GO:0007070)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.
Synonyms: down regulation of transcription from RNA polymerase II promoter during mitosis; down-regulation of transcription from RNA polymerase II promoter during mitosis; downregulation of transcription from RNA polymerase II promoter during mitosis; inhibition of transcription from RNA polymerase II promoter during mitosis; mitotic repression of transcription from Pol II promoter; negative regulation of transcription from Pol II promoter during mitosis; negative regulation of transcription from RNA polymerase II promoter, mitotic
Comment: The reason for obsoletion is that 'during' should be captured using an annotation extension.
obsolete positive regulation of transcription involved in exit from mitosis (GO:0007072)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
Synonyms: activation of transcription on exit from mitosis
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter (GO:0007073)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
Synonyms: activation of transcription on exit from mitosis, from Pol I promoter; activation of transcription on exit from mitosis, from RNA polymerase I promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter (GO:0007074)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
Synonyms: activation of transcription on exit from mitosis, from Pol II promoter; activation of transcription on exit from mitosis, from RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter (GO:0007075)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
Synonyms: activation of transcription on exit from mitosis, from Pol III promoter; activation of transcription on exit from mitosis, from RNA polymerase III promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
mitotic chromosome condensation (GO:0007076)
Namespace: biological_process
Definition: The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
mitotic nuclear membrane disassembly (GO:0007077)
Namespace: biological_process
Definition: The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis.
Synonyms: local NEB; mitotic nuclear envelope breakdown; mitotic nuclear envelope catabolism; mitotic nuclear envelope degradation; mitotic nuclear envelope disassembly; NEB; nuclear envelope breakdown
mitotic chromosome movement towards spindle pole (GO:0007079)
Namespace: biological_process
Definition: The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
Synonyms: chromosome migration to spindle pole during mitosis; chromosome movement towards spindle pole during mitosis; mitotic chromosome movement; mitotic chromosome movement to spindle pole; mitotic sister chromosome movement towards spindle pole; sister chromosome movement towards spindle pole during mitosis
mitotic metaphase chromosome alignment (GO:0007080)
Namespace: biological_process
Definition: A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during mitotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
obsolete mitotic chromosome decondensation (GO:0007083)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.
Comment: This term was obsoleted because it is a spontaneous process.
mitotic nuclear membrane reassembly (GO:0007084)
Namespace: biological_process
Definition: The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.
Synonyms: mitotic nuclear envelope reassembly; nuclear envelope repair; nuclear envelope resealing
obsolete nuclear membrane vesicle binding to chromatin (GO:0007085)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: nuclear membrane vesicle binding to chromatin
Comment: This term was made obsolete because it represents a molecular function.
obsolete vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly (GO:0007086)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mitotic nuclear pore complex reassembly (GO:0007087)
Namespace: biological_process
Definition: The cell cycle process in which nuclear pore complexes reform during mitotic cell division.
regulation of mitotic nuclear division (GO:0007088)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mitosis.
Synonyms: regulation of mitosis
traversing start control point of mitotic cell cycle (GO:0007089)
Namespace: biological_process
Definition: A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
obsolete regulation of S phase of mitotic cell cycle (GO:0007090)
Namespace: biological_process
Definition: OBSOLETE. A cell cycle process that modulates the frequency, rate or extent of the progression through the S phase of the mitotic cell cycle.
Synonyms: regulation of S phase of mitotic cell cycle; regulation of S-phase of mitotic cell cycle
Comment: This term was made obsolete as part of the cell cycle overhaul. This is because it was decided that cell cycle phases are intervals and so cannot be regulated, rather it is the transitions between the phases that are regulated.
metaphase/anaphase transition of mitotic cell cycle (GO:0007091)
Namespace: biological_process
Definition: The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
Synonyms: metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; mitotic metaphase/anaphase transition
mitotic cell cycle checkpoint signaling (GO:0007093)
Namespace: biological_process
Definition: A signaling process that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
Synonyms: mitotic cell cycle checkpoint; mitotic checkpoint; signal transduction involved in mitotic cell cycle checkpoint; signal transduction involved in mitotic cell cycle G1/S checkpoint; signal transduction involved in mitotic G2/M transition checkpoint
mitotic spindle assembly checkpoint signaling (GO:0007094)
Namespace: biological_process
Definition: A mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC).
Synonyms: Dma1-dependent checkpoint; Mad2-dependent checkpoint; mitotic cell cycle spindle assembly checkpoint; mitotic checkpoint; mitotic spindle assembly checkpoint; mitotic spindle assembly checkpoint signalling; SAC-independent checkpoint; signal transduction involved in Dma1-dependent checkpoint; signal transduction involved in mitotic cell cycle spindle assembly checkpoint; signal transduction involved in mitotic spindle assembly checkpoint; signal transduction involved in SAC-independent checkpoint; signaling cascade involved in Dma1-dependent checkpoint; signaling cascade involved in SAC-independent checkpoint; signaling pathway involved in Dma1-dependent checkpoint; signaling pathway involved in SAC-independent checkpoint; signalling cascade involved in Dma1-dependent checkpoint; signalling cascade involved in SAC-independent checkpoint; signalling pathway involved in Dma1-dependent checkpoint; signalling pathway involved in SAC-independent checkpoint
mitotic G2 DNA damage checkpoint signaling (GO:0007095)
Namespace: biological_process
Definition: A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
Synonyms: down regulation of signal transduction involved in mitotic G2 DNA damage checkpoint; down regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint; down-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint; down-regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint; G2 DNA damage checkpoint; G2/M transition DNA damage checkpoint; inhibition of signal transduction involved in mitotic G2 DNA damage checkpoint; mitotic cell cycle G2/M transition DNA damage checkpoint; mitotic G2 DNA damage checkpoint; negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint; negative regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint; positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint; positive regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint; regulation of signal transduction involved in mitotic G2 DNA damage checkpoint; regulation of signal transduction involved in mitotic G2/M transition DNA damage checkpoint; signal transduction involved in G2 DNA damage checkpoint; signal transduction involved in G2/M transition DNA damage checkpoint; signal transduction involved in mitotic G2 DNA damage checkpoint; signal transduction involved in mitotic G2/M transition DNA damage checkpoint
regulation of exit from mitosis (GO:0007096)
Namespace: biological_process
Definition: Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
nuclear migration (GO:0007097)
Namespace: biological_process
Definition: The directed movement of the nucleus to a specific location within a cell.
Synonyms: establishment of cell nucleus localization; establishment of localization of nucleus; establishment of nucleus localisation; establishment of nucleus localization; establishment of position of nucleus; nuclear movement; nuclear positioning; nucleus migration; nucleus positioning; positioning of nucleus
centrosome cycle (GO:0007098)
Namespace: biological_process
Definition: The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
Synonyms: centrosome organisation; centrosome organization; centrosome organization and biogenesis
centriole replication (GO:0007099)
Namespace: biological_process
Definition: The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
Synonyms: centriole duplication; ciliary basal body duplication; microtubule basal body duplication
mitotic centrosome separation (GO:0007100)
Namespace: biological_process
Definition: Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
obsolete male meiosis centrosome cycle (GO:0007101)
Namespace: biological_process
Definition: OBSOLETE. Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.
Synonyms: centrosome cycle involved in male meiotic cell cycle
Comment: false
cytokinesis, division site positioning (GO:0007105)
Namespace: biological_process
Definition: The process in which a contractile ring is positioned in a specific location. This process is critical for both for both symmetric and asymmetric cell divisions.
Synonyms: contractile ring localization; cytokinesis, site selection; division plane positioning; site selection involved in cell cycle cytokinesis; site selection involved in cytokinesis
obsolete cytokinesis, protein recruitment (GO:0007106)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytokinesis, protein recruitment
Comment: This term was made obsolete because it was not defined.
membrane addition at site of cytokinesis (GO:0007107)
Namespace: biological_process
Definition: Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
Synonyms: cytokinesis, membrane recruitment/generation
obsolete cytokinesis, initiation of separation (GO:0007108)
Namespace: biological_process
Definition: OBSOLETE. The process involved in starting cell separation.
Synonyms: cytokinesis, initiation of separation; initiation of separation involved in cytokinesis
Comment: This term was obsoleted because it was vaguely defined and had very likely been used in error. Consider the child terms of cytokinesis related to ring positioning, assembly, ring constriction etc. which would be more appropriate.
meiosis I cytokinesis (GO:0007110)
Namespace: biological_process
Definition: A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
Synonyms: cytokinesis after meiosis I
meiosis II cytokinesis (GO:0007111)
Namespace: biological_process
Definition: A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
Synonyms: cytokinesis after meiosis II
male meiosis cytokinesis (GO:0007112)
Namespace: biological_process
Definition: A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.
Synonyms: cytokinesis after male meiosis; cytokinesis involved in male meiotic cell cycle
endomitotic cell cycle (GO:0007113)
Namespace: biological_process
Definition: A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
Synonyms: endomitosis
Comment: Note that this term should not be confused with 'abortive mitotic cell cycle ; GO:0033277'. Although abortive mitosis is sometimes called endomitosis, GO:0033277 refers to a process in which a mitotic spindle forms and chromosome separation begins.
cell budding (GO:0007114)
Namespace: biological_process
Definition: A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
Synonyms: budding
obsolete bud site selection/establishment of cell polarity (sensu Saccharomyces) (GO:0007115)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: bud site selection/establishment of cell polarity (sensu Saccharomyces)
Comment: This term was made obsolete because it represents two processes.
regulation of cell budding (GO:0007116)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.
Synonyms: regulation of budding
budding cell isotropic bud growth (GO:0007119)
Namespace: biological_process
Definition: Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.
Synonyms: isotropic bud growth
axial cellular bud site selection (GO:0007120)
Namespace: biological_process
Definition: The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.
Synonyms: axial bud site selection; axial budding
bipolar cellular bud site selection (GO:0007121)
Namespace: biological_process
Definition: The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
Synonyms: bipolar bud site selection; bipolar budding; polar budding
obsolete loss of asymmetric budding (GO:0007122)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: loss of asymmetric budding
Comment: This term was made obsolete because it is a phenotype rather than a biological process.
obsolete bud scar accumulation (GO:0007123)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: bud scar accumulation
Comment: This term was made obsolete because it is a phenotype rather than a biological process.
pseudohyphal growth (GO:0007124)
Namespace: biological_process
Definition: The process in which cells grow as a chain of physically attached, elongated cells in response to an environmental stimulus or stimuli.
obsolete invasive growth (GO:0007125)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: invasive growth
Comment: This term was made obsolete because it has been split into two new terms.
meiosis I (GO:0007127)
Namespace: biological_process
Definition: The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
Synonyms: meiosis I nuclear division
meiotic prophase I (GO:0007128)
Namespace: biological_process
Definition: The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
homologous chromosome pairing at meiosis (GO:0007129)
Namespace: biological_process
Definition: The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
Synonyms: chromosomal pairing; chromosomal synapsis; synapsis
synaptonemal complex assembly (GO:0007130)
Namespace: biological_process
Definition: The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
Synonyms: synaptonemal complex formation
reciprocal meiotic recombination (GO:0007131)
Namespace: biological_process
Definition: The cell cycle process in which double strand breaks are formed and repaired through a single or double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
Synonyms: female meiotic recombination; gene conversion with reciprocal crossover