LiteFold/GO huggingface dataset:
secondary active p-aminobenzoyl-glutamate transmembrane transporter activity (GO:0015558)
Namespace: molecular_function
Definition: Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.
Synonyms: p-aminobenzoyl-glutamate transmembrane transporter activity; p-aminobenzoyl-glutamate transporter activity; p-aminobenzoyl-glutamate uptake permease activity; p-aminobenzoyl-glutamate uptake transmembrane transporter activity
obsolete L-idonate/D-gluconate:hydrogen symporter activity (GO:0015560)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (L-idonate or D-gluconate)(out) + H+(out) = (L-iodonate or D-gluconate)(in) + H+(in).
Synonyms: L-idonate/D-gluconate:hydrogen symporter activity; L-idonate/D-gluconate:proton symporter
Comment: This term was made obsolete because it represents a multifunctional gene product.
rhamnose:proton symporter activity (GO:0015561)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).
Synonyms: rhamnose:hydrogen symporter activity
efflux transmembrane transporter activity (GO:0015562)
Namespace: molecular_function
Definition: Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
Synonyms: efflux permease activity; efflux transporter activity; monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
obsolete acriflavine transmembrane transporter activity (GO:0015566)
Namespace: molecular_function
Definition: OBSOLETE. Enables the directed movement of acriflavin from one side of a membrane to the other. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.
Synonyms: acriflavin resistant pump activity; acriflavin transporter activity; acriflavine transporter activity
Comment: The reason for obsoletion is that these terms are beyond the scope of GO.
alkane transmembrane transporter activity (GO:0015567)
Namespace: molecular_function
Definition: Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.
L-idonate transmembrane transporter activity (GO:0015568)
Namespace: molecular_function
Definition: Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
Synonyms: L-idonate/D-gluconate:hydrogen symporter activity
N-acetylgalactosamine transmembrane transporter activity (GO:0015571)
Namespace: molecular_function
Definition: Enables the transfer of N-acetylgalactosamine from one side of a membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
Synonyms: N-acetylgalactosamine permease activity
N-acetylglucosamine transmembrane transporter activity (GO:0015572)
Namespace: molecular_function
Definition: Enables the transfer of N-acetylglucosamine from one side of a membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
Synonyms: D-GlcNAc transmembrane transporter activity; N-Acetyl-D-glucosamine permease; N-acetyl-D-glucosamine transmembrane transporter activity; N-acetylchitosamine transmembrane transporter activity; N-acetylglucosamine permease activity
beta-glucoside transmembrane transporter activity (GO:0015573)
Namespace: molecular_function
Definition: Enables the transfer of beta-glucosides from one side of a membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
Synonyms: beta-glucoside permease activity
trehalose transmembrane transporter activity (GO:0015574)
Namespace: molecular_function
Definition: Enables the transfer of trehalose from one side of a membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.
Synonyms: trehalose permease activity
mannitol transmembrane transporter activity (GO:0015575)
Namespace: molecular_function
Definition: Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
Synonyms: mannitol permease activity
sorbitol transmembrane transporter activity (GO:0015576)
Namespace: molecular_function
Definition: Enables the transfer of sorbitol from one side of a membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.
Synonyms: glucitol permease activity; glucitol transporter activity; sorbitol permease activity
galactitol transmembrane transporter activity (GO:0015577)
Namespace: molecular_function
Definition: Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
Synonyms: galactitol permease activity
mannose transmembrane transporter activity (GO:0015578)
Namespace: molecular_function
Definition: Enables the transfer of mannose from one side of a membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
Synonyms: mannose permease activity
obsolete beta-glucoside [arbutin-salicin-cellobiose] permease activity (GO:0015583)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). The beta-glucoside may be arbutin, salicin or cellobiose.
Synonyms: beta-glucoside [arbutin-salicin-cellobiose] permease activity
Comment: This term was made obsolete because it arbitrarily groups three substrates.
D-ribose transmembrane transporter activity (GO:0015591)
Namespace: molecular_function
Definition: Enables the transfer of D-ribose from one side of a membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
methylgalactoside transmembrane transporter activity (GO:0015592)
Namespace: molecular_function
Definition: Enables the transfer of methylgalactoside from one side of a membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
Synonyms: galactose/glucose (methylgalactoside) porter activity
obsolete allose transmembrane transporter activity (GO:0015593)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
Comment: This term was obsoleted because there is no evidence that this activity exists.
ABC-type putrescine transporter activity (GO:0015594)
Namespace: molecular_function
Definition: Catalysis of the reaction: putrescine(out) + ATP + H2O = putrescine(in) + ADP + phosphate + H+.
Synonyms: ATPase-coupled putrescine transmembrane transporter activity; putrescine porter activity; putrescine-importing ATPase activity
obsolete glycine betaine/proline porter activity (GO:0015596)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).
Synonyms: glycine betaine/proline porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
obsolete histidine/arginine/lysine/ornithine porter activity (GO:0015597)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).
Synonyms: histidine/arginine/lysine/ornithine porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
ATPase-coupled L-glutamine transmembrane transporter activity (GO:0015599)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + ATP + H2O = L-glutamine(in) + ADP + phosphate + H+.
Synonyms: ATPase-coupled glutamine transmembrane transporter activity; glutamine porter activity; glutamine-importing ATPase activity
obsolete glutamate/aspartate porter activity (GO:0015600)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).
Synonyms: glutamate/aspartate porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
obsolete cystine/diaminopimelate porter activity (GO:0015601)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).
Synonyms: cystine/diaminopimelate porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
obsolete leucine/isoleucine/valine porter activity (GO:0015602)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).
Synonyms: leucine/isoleucine/valine porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
iron chelate transmembrane transporter activity (GO:0015603)
Namespace: molecular_function
Definition: Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
organophosphate ester transmembrane transporter activity (GO:0015605)
Namespace: molecular_function
Definition: Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.
spermidine transmembrane transporter activity (GO:0015606)
Namespace: molecular_function
Definition: Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
ABC-type fatty-acyl-CoA transporter activity (GO:0015607)
Namespace: molecular_function
Definition: Catalysis of the reaction ATP + H2O + fatty acyl CoA(Side 1) = ADP + phosphate + fatty acyl CoA(Side 2). A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.
Synonyms: ABC-type fatty-acyl-CoA transporter; ATPase-coupled fatty-acyl-CoA transmembrane transporter activity; fatty acyl CoA transporter activity; fatty-acyl-CoA transmembrane transporter activity; fatty-acyl-CoA-transporting ATPase
obsolete carbohydrate-importing ABC transporter activity (GO:0015608)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).
Comment: This term was obsoleted because it had no annotations and no PMID references, and the TC:3.A.1.1.1 xref specifically refers to the Maltooligosaccharide porter which is already covered by GO:0015423.
ABC-type L-arabinose transporter activity (GO:0015612)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) = ADP + phosphate + L-arabinose(in).
Synonyms: L-arabinose porter activity; L-arabinose-importing ATPase activity
obsolete galactose/glucose (methylgalactoside) porter activity (GO:0015613)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: galactose/glucose (methylgalactoside) porter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
ABC-type D-xylose transporter activity (GO:0015614)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) = ADP + phosphate + D-xylose(in).
Synonyms: ATPase-coupled D-xylose transmembrane transporter activity; D-xylose porter activity; D-xylose-importing ATPase activity
DNA translocase activity (GO:0015616)
Namespace: molecular_function
Definition: Generation of movement along a single- or double-stranded DNA molecule, driven by ATP hydrolysis.
Comment: Note that some gene products that possess DNA translocase activity, such as members of the FtsK/SpoIIIE family, can be fixed in place by interactions with other components of the cell; the relative movement between the protein and DNA bound to it results in movement of the DNA within the cell, often across a membrane.
obsolete pilin/fimbrilin exporter activity (GO:0015617)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: pilin/fimbrilin exporter activity
Comment: This term was made obsolete because it represents a gene product.
ferric-enterobactin transmembrane transporter activity (GO:0015620)
Namespace: molecular_function
Definition: Enables the transfer of ferric-enterobactin from one side of a membrane to the other.
ferric triacetylfusarinine C transmembrane transporter activity (GO:0015621)
Namespace: molecular_function
Definition: Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.
ABC-type ferric hydroxamate transporter activity (GO:0015625)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).
Synonyms: ATP-dependent ferric-hydroxamate transmembrane transporter activity; ATP-dependent iron-chelate transporter activity; ATPase-coupled ferric-hydroxamate transmembrane transporter activity; ATPase-coupled iron-chelate transporter activity; ferric-hydroxamate ABC transporter; ferric-hydroxamate porter activity; ferric-hydroxamate transmembrane transporter activity; ferric-hydroxamate-transporting ATPase activity; iron-chelate-transporting ATPase activity
L-diaminopimelate transmembrane transporter activity (GO:0015626)
Namespace: molecular_function
Definition: Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.
Synonyms: cystine/diaminopimelate porter activity; L-diaminopimelate transporter activity
type II protein secretion system complex (GO:0015627)
Namespace: cellular_component
Definition: A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
Synonyms: general secretion pathway-associated complex; main terminal branch; MTB; Sec-dependent secretion system-associated complex; T2SS-associated complexes
Comment: Note that the type II protein secretion system complex does not include components of the Sec or Tat pathways. For components of these pathways, consider annotating to 'cell envelope Sec complex ; GO:0031522' or 'TAT protein translocation system complex ; GO:0033281'.
protein secretion by the type II secretion system (GO:0015628)
Namespace: biological_process
Definition: The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.
Synonyms: protein secretion by the general secretion pathway; protein secretion by the general secretory pathway; protein secretion by the T2S; protein secretion by the T2SS; protein secretion by the type II protein secretion system; type II protein secretion system
Comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular component term 'type II protein secretion system complex ; GO:0015627'. This process refers specifically to secretion across the outer membrane. For components of the Sec and Tat pathways, consider annotating to 'protein transport by the Sec complex ; GO:0043952' and 'protein transport by the Tat complex ; GO:0043953'. Note that this term is used for annotation of proteins that compose the secretion complex but not the proteins being secreted.
actin cytoskeleton (GO:0015629)
Namespace: cellular_component
Definition: The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
microtubule cytoskeleton (GO:0015630)
Namespace: cellular_component
Definition: The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
tubulin binding (GO:0015631)
Namespace: molecular_function
Definition: Binding to monomeric or multimeric forms of tubulin, including microtubules.
ABC-type zinc transporter activity (GO:0015633)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).
Synonyms: ATP-dependent zinc transmembrane transporter activity; ATPase-coupled zinc transmembrane transporter activity; zinc porter activity; zinc transporting ATPase activity; zinc-transporting ATPase activity
obsolete lipopolysaccharide exporter activity (GO:0015634)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
Synonyms: LPS exporter activity
Comment: This term was obsoleted because export is a process, not a function.
short-chain fatty acid transmembrane transporter activity (GO:0015636)
Namespace: molecular_function
Definition: Enables the transfer of short-chain fatty acids from one side of a membrane to the other. A short-chain fatty acid has an aliphatic tail containing fewer than 6 carbons.
Synonyms: short-chain fatty acid transporter activity; short-chain fatty acid uptake transporter activity
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
microcin transmembrane transporter activity (GO:0015638)
Namespace: molecular_function
Definition: Enables the transfer of a microcin from one side of a membrane to the other.
Synonyms: microcin uptake permease activity
peptidoglycan peptide transmembrane transporter activity (GO:0015640)
Namespace: molecular_function
Definition: Enables the transfer of peptidoglycan peptides from one side of a membrane to the other. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.
Synonyms: murein peptide transporter activity; muropeptide transporter activity
obsolete lipoprotein toxin (GO:0015641)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: lipoprotein toxin
Comment: This term was made obsolete because it represents a gene product.
obsolete bacteriolytic toxin activity (GO:0015642)
Namespace: molecular_function
Definition: OBSOLETE. Acts as to cause lysis of bacterial cells.
Synonyms: bacteriolytic toxin activity
Comment: This term was made obsolete because it represents a class of gene products and not a molecular function.
obsolete lipoprotein antitoxin (GO:0015644)
Namespace: molecular_function
Definition: OBSOLETE. Binds to a lipoprotein toxin, which is usually derived from a microorganism, thereby neutralizing it.
Synonyms: lipoprotein antitoxin
Comment: This term was made obsolete because it does not represent a function distinct from its parent term.
fatty acid ligase activity (GO:0015645)
Namespace: molecular_function
Definition: Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.
Synonyms: fatty acid CoA ligase activity; fatty acyl-coenzyme A synthetase activity; fatty-acid ligase activity
peptidoglycan transmembrane transporter activity (GO:0015647)
Namespace: molecular_function
Definition: Enables the transfer of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, from one side of a membrane to the other.
Synonyms: murein transporter activity
lipid-linked peptidoglycan transporter activity (GO:0015648)
Namespace: molecular_function
Definition: Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.
Synonyms: lipid-linked murein transporter activity
2-keto-3-deoxygluconate:proton symporter activity (GO:0015649)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).
Synonyms: 2-keto-3-deoxygluconate:hydrogen symporter activity
lactate:proton symporter activity (GO:0015650)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).
Synonyms: lactate permease; lactate:hydrogen porter activity; lactate:hydrogen symporter activity; lactate:proton porter activity
quaternary ammonium group transmembrane transporter activity (GO:0015651)
Namespace: molecular_function
Definition: Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
Synonyms: quaternary amine transmembrane transporter activity; quaternary ammonium compound transporter activity
quaternary ammonium group:proton symporter activity (GO:0015652)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).
Synonyms: quaternary ammonium group:hydrogen symporter activity