LiteFold/GO huggingface dataset:
regulation of D-glucose transmembrane transport (GO:0010827)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: regulation of glucose transmembrane transport; regulation of glucose transport
positive regulation of D-glucose transmembrane transport (GO:0010828)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: positive regulation of glucose transmembrane transport; positive regulation of glucose transport
negative regulation of D-glucose transmembrane transport (GO:0010829)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: negative regulation of glucose transmembrane transport; negative regulation of glucose transport
positive regulation of myotube differentiation (GO:0010831)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
negative regulation of myotube differentiation (GO:0010832)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
telomere maintenance via telomere lengthening (GO:0010833)
Namespace: biological_process
Definition: Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.
obsolete telomere maintenance via telomere shortening (GO:0010834)
Namespace: biological_process
Definition: OBSOLETE. Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and shortening the telomeric DNA.
Synonyms: telomere maintenance via telomere shortening
Comment: This term was made obsolete because it represents a phenotype.
regulation of protein ADP-ribosylation (GO:0010835)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
Synonyms: regulation of protein amino acid ADP-ribosylation
regulation of keratinocyte proliferation (GO:0010837)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
positive regulation of keratinocyte proliferation (GO:0010838)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
negative regulation of keratinocyte proliferation (GO:0010839)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
regulation of circadian sleep/wake cycle, wakefulness (GO:0010840)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
positive regulation of circadian sleep/wake cycle, wakefulness (GO:0010841)
Namespace: biological_process
Definition: Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
retina layer formation (GO:0010842)
Namespace: biological_process
Definition: The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
Synonyms: retinal lamination; retinal layer formation
obsolete promoter binding (GO:0010843)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a regulatory region composed of the transcription start site and binding sites for transcription factor complexes of the basal transcription machinery.
Synonyms: DNA binding, transcription promoter; promoter binding
Comment: This term was made obsolete because the word "promoter" is used ambiguously in the literature. It sometimes is used to refer specifically to the "core promoter" region recognized by the basal transcription machinery, and other times is used to refer to a larger regulatory region composed of the core promoter and also the regulatory region adjacent (proximal) to the core promoter. The core promoter proximal region is typically recognized by "regulatory transcription factors", such as Gal4 in S. cerevisiae.
recombination hotspot binding (GO:0010844)
Namespace: molecular_function
Definition: Binding to a genomic region which promotes recombination.
Synonyms: DNA binding, recombination hotspot
positive regulation of reciprocal meiotic recombination (GO:0010845)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
Synonyms: positive regulation of meiotic recombination
activation of reciprocal meiotic recombination (GO:0010846)
Namespace: biological_process
Definition: Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
Synonyms: activation of meiotic recombination
obsolete regulation of chromatin assembly (GO:0010847)
Namespace: biological_process
Definition: OBSOLETE. Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
Comment: This term was obsoleted because 'chromatin assembly' was merged into 'chromatin organization'.
obsolete regulation of chromatin disassembly (GO:0010848)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.
Comment: This term has been obsoleted because this process doesn't happen independently from assembly and is always tied to chromatin remodeling.
obsolete regulation of proton-transporting ATPase activity, rotational mechanism (GO:0010849)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate of ATP hydrolysis by an ATPase. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
Synonyms: regulation of hydrogen ion transporting ATPase activity, rotational mechanism; regulation of V-type ATPase activity
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
regulation of blood pressure by chemoreceptor signaling pathway (GO:0010850)
Namespace: biological_process
Definition: A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
Synonyms: regulation of blood pressure by chemoreceptor signalling pathway
cyclase regulator activity (GO:0010851)
Namespace: molecular_function
Definition: Binds to and modulates the activity of an enzyme that catalyzes a ring closure reaction.
cyclase inhibitor activity (GO:0010852)
Namespace: molecular_function
Definition: Binds to and decreases the activity of an enzyme that catalyzes a ring closure reaction.
cyclase activator activity (GO:0010853)
Namespace: molecular_function
Definition: Binds to and increases the activity of an enzyme that catalyzes a ring closure reaction.
calcium-dependent protein kinase regulator activity (GO:0010858)
Namespace: molecular_function
Definition: Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.
calcium-dependent cysteine-type endopeptidase inhibitor activity (GO:0010859)
Namespace: molecular_function
Definition: Binds to and stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.
obsolete proteasome regulator activity (GO:0010860)
Namespace: molecular_function
Definition: OBSOLETE. Modulates the activity of the proteasome complex. The proteasome complex performs regulated ubiquitin-dependent cytosolic and nuclear proteolysis.
Synonyms: proteasome regulator activity
Comment: The term was made obsolete because 'proteasome' is not a valid molecular function term.
obsolete positive regulation of phospholipase C activity (GO:0010863)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate of phospholipase C activity.
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete positive regulation of protein histidine kinase activity (GO:0010864)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of protein histidine kinase activity.
Comment: This term was obsoleted because it represents a molecular function.
stipule development (GO:0010865)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.
regulation of triglyceride biosynthetic process (GO:0010866)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
Synonyms: regulation of triacylglycerol biosynthetic process
positive regulation of triglyceride biosynthetic process (GO:0010867)
Namespace: biological_process
Definition: Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
Synonyms: positive regulation of triacylglycerol biosynthetic process
negative regulation of triglyceride biosynthetic process (GO:0010868)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
Synonyms: negative regulation of triacylglycerol biosynthetic process
obsolete regulation of receptor biosynthetic process (GO:0010869)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Comment: The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.
obsolete positive regulation of receptor biosynthetic process (GO:0010870)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Comment: The reason for obsoletion is that those represent specific gene products, and genes annotated to those terms should be annotated to 'regulation of gene expression' or 'regulation of transcription' or some signaling term.
obsolete regulation of cholesterol esterification (GO:0010872)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of cholesterol esterification (GO:0010873)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
Comment: This term was obsoleted because it represents a molecular function.
regulation of cholesterol efflux (GO:0010874)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
positive regulation of cholesterol efflux (GO:0010875)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
lipid localization (GO:0010876)
Namespace: biological_process
Definition: Any process in which a lipid is transported to, or maintained in, a specific location.
Synonyms: lipid localisation
cholesterol transport involved in cholesterol storage (GO:0010879)
Namespace: biological_process
Definition: The directed movement of cholesterol into cells that is part of their accumulation and maintenance.
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO:0010881)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.
Synonyms: regulation of cardiac muscle contraction by calcium ion signalling
regulation of lipid storage (GO:0010883)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
Synonyms: regulation of lipid sequestration
positive regulation of lipid storage (GO:0010884)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
Synonyms: positive regulation of lipid sequestration
regulation of cholesterol storage (GO:0010885)
Namespace: biological_process
Definition: Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
positive regulation of cholesterol storage (GO:0010886)
Namespace: biological_process
Definition: Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms: positive regulation of cholesterol sequestration
negative regulation of lipid storage (GO:0010888)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
regulation of triglyceride storage (GO:0010889)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
Synonyms: regulation of sequestering of triacylglycerol; regulation of sequestering of triglyceride; regulation of triacylglycerol sequestration
positive regulation of triglyceride storage (GO:0010890)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
Synonyms: positive regulation of sequestering of triacylglycerol; positive regulation of sequestering of triglyceride; positive regulation of triglyceride sequestration
negative regulation of triglyceride storage (GO:0010891)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
Synonyms: negative regulation of sequestering of triacylglycerol; negative regulation of sequestering of triglyceride; negative regulation of triglyceride sequestration
positive regulation of mitochondrial translation in response to stress (GO:0010892)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.
positive regulation of steroid biosynthetic process (GO:0010893)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
negative regulation of steroid biosynthetic process (GO:0010894)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
regulation of triglyceride catabolic process (GO:0010896)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
Synonyms: regulation of triacylglycerol catabolic process
negative regulation of triglyceride catabolic process (GO:0010897)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
Synonyms: negative regulation of triacylglycerol catabolic process
regulation of phosphatidylcholine catabolic process (GO:0010899)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.