LiteFold/GO huggingface dataset:
regulation of trehalose metabolic process (GO:0090062)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide that consists of two molecules of glucose and is isomeric with sucrose.
positive regulation of microtubule nucleation (GO:0090063)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
activation of microtubule nucleation (GO:0090064)
Namespace: biological_process
Definition: Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
regulation of anatomical structure size (GO:0090066)
Namespace: biological_process
Definition: Any process that modulates the size of an anatomical structure.
regulation of thalamus size (GO:0090067)
Namespace: biological_process
Definition: Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.
positive regulation of cell cycle process (GO:0090068)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
regulation of ribosome biogenesis (GO:0090069)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
positive regulation of ribosome biogenesis (GO:0090070)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
negative regulation of ribosome biogenesis (GO:0090071)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
obsolete positive regulation of sodium ion transport via voltage-gated sodium channel activity (GO:0090072)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the directed movement of sodium ions via the activity of voltage-gated sodium channels.
Synonyms: positive regulation of sodium ion transport via voltage-gated sodium channel activity
Comment: This term was made obsolete because it is ill-defined: channel activities are part of ion transport processes, and not the other way round.
obsolete positive regulation of protein homodimerization activity (GO:0090073)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of protein homodimerization activity (GO:0090074)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
relaxation of muscle (GO:0090075)
Namespace: biological_process
Definition: A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.
relaxation of skeletal muscle (GO:0090076)
Namespace: biological_process
Definition: A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
foam cell differentiation (GO:0090077)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
smooth muscle derived foam cell differentiation (GO:0090078)
Namespace: biological_process
Definition: The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
obsolete translation regulator activity, nucleic acid binding (GO:0090079)
Namespace: molecular_function
Definition: OBSOLETE. Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
Comment: This term was added in error, unnecessary grouping term
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (GO:0090080)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.
Synonyms: positive regulation of MAPKKK cascade by fibroblast growth factor receptor signalling pathway
obsolete regulation of heart induction by regulation of canonical Wnt signaling pathway (GO:0090081)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: regulation of heart induction by regulation of canonical Wnt receptor signaling pathway; regulation of heart induction by regulation of canonical Wnt receptor signalling pathway; regulation of heart induction by regulation of canonical Wnt-activated signaling pathway
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway (GO:0090082)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway; positive regulation of heart induction by negative regulation of canonical Wnt receptor signalling pathway; positive regulation of heart induction by negative regulation of canonical Wnt-activated signaling pathway
Comment: This term was obsoleted because it represents a GO-CAM model.
regulation of inclusion body assembly (GO:0090083)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
negative regulation of inclusion body assembly (GO:0090084)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
regulation of protein deubiquitination (GO:0090085)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
negative regulation of protein deubiquitination (GO:0090086)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
regulation of dipeptide transport (GO:0090089)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of canonical Wnt signaling pathway (GO:0090090)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: negative regulation of canonical Wnt receptor signaling pathway; negative regulation of canonical Wnt receptor signalling pathway; negative regulation of canonical Wnt-activated signaling pathway; negative regulation of catenin import into nucleus; negative regulation of catenin protein nuclear translocation; negative regulation of Wnt receptor signaling pathway through beta-catenin
positive regulation of extracellular matrix disassembly (GO:0090091)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms: regulation of transmembrane receptor protein serine/threonine kinase signalling pathway
regulation of fungal-type cell wall beta-glucan biosynthetic process (GO:0090093)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
metanephric cap mesenchymal cell proliferation involved in metanephros development (GO:0090094)
Namespace: biological_process
Definition: The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
positive regulation of metanephric cap mesenchymal cell proliferation (GO:0090096)
Namespace: biological_process
Definition: Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Synonyms: negative regulation of transmembrane receptor protein serine/threonine kinase signalling pathway
cochlea development (GO:0090102)
Namespace: biological_process
Definition: The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.
pancreatic epsilon cell differentiation (GO:0090104)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.
Synonyms: pancreatic E cell differentiation
pancreatic E cell development (GO:0090105)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.
pancreatic E cell fate commitment (GO:0090106)
Namespace: biological_process
Definition: The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.
regulation of high-density lipoprotein particle assembly (GO:0090107)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
positive regulation of high-density lipoprotein particle assembly (GO:0090108)
Namespace: biological_process
Definition: Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
regulation of cell-substrate junction assembly (GO:0090109)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
COPII-coated vesicle cargo loading (GO:0090110)
Namespace: biological_process
Definition: The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
Synonyms: cargo loading into COPII vesicle; cargo loading into COPII-coated vesicle; cargo selection into COPII-coated vesicle; COPII coat-cargo complex assembly
regulation of COPII vesicle uncoating (GO:0090111)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.
obsolete regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis (GO:0090113)
Namespace: biological_process
Definition: OBSOLETE. The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles.
Comment: This term was obsoleted because it represents a molecular function and a biological process.
COPII-coated vesicle budding (GO:0090114)
Namespace: biological_process
Definition: The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
Synonyms: COPII vesicle budding; ER exit; ER vesicle budding
obsolete C-5 methylation on cytosine involved in chromatin silencing (GO:0090115)
Namespace: biological_process
Definition: OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing.
Comment: This term was obsoleted because it represents a molecular function.
obsolete C-5 methylation of cytosine (GO:0090116)
Namespace: biological_process
Definition: OBSOLETE. The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.
Comment: This term was obsoleted because it represents a molecular function.
endosome to lysosome transport of low-density lipoprotein particle (GO:0090117)
Namespace: biological_process
Definition: The directed movement of low-density lipoprotein particle from endosomes to lysosomes.
Synonyms: endosome to lysosome transport of LDL
receptor-mediated endocytosis involved in cholesterol transport (GO:0090118)
Namespace: biological_process
Definition: A receptor-mediated endocytosis process involved in intracellular cholesterol transport.
Synonyms: receptor-mediated endocytosis involved in intracellular cholesterol transport; receptor-mediated endocytosis of LDL; receptor-mediated endocytosis of low-density lipoprotein involved in cholesterol transport; receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport
vesicle-mediated cholesterol transport (GO:0090119)
Namespace: biological_process
Definition: The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.
lysosome to ER cholesterol transport (GO:0090120)
Namespace: biological_process
Definition: The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.
Synonyms: lysosome to endoplasmic reticulum cholesterol transport
obsolete low-density lipoprotein particle disassembly involved in cholesterol transport (GO:0090121)
Namespace: biological_process
Definition: OBSOLETE. The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
cholesterol ester hydrolysis involved in cholesterol transport (GO:0090122)
Namespace: biological_process
Definition: The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
lysosomal glycocalyx (GO:0090123)
Namespace: cellular_component
Definition: The polysaccharide-based coating on the inner side of a lysosomal membrane. It may be involved in protecting the membrane from digestion by lysosomal enzymes.
obsolete N-4 methylation of cytosine (GO:0090124)
Namespace: biological_process
Definition: OBSOLETE. The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule.
Comment: This term was obsoleted because it represents a molecular function.
protein-containing complex assembly involved in synapse maturation (GO:0090126)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.
Synonyms: protein complex assembly involved in synapse maturation
positive regulation of synapse maturation by synaptic transmission (GO:0090127)
Namespace: biological_process
Definition: Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.
regulation of synapse maturation (GO:0090128)
Namespace: biological_process
Definition: Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
positive regulation of synapse maturation (GO:0090129)
Namespace: biological_process
Definition: Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
tissue migration (GO:0090130)
Namespace: biological_process
Definition: The process in which the population of cells that make up a tissue undergo directed movement.
mesenchyme migration (GO:0090131)
Namespace: biological_process
Definition: The process in which the population of cells that make up a mesenchyme undergo directed movement.
epithelium migration (GO:0090132)
Namespace: biological_process
Definition: The process in which the population of cells that make up an epithelium undergo directed movement.
mesendoderm migration (GO:0090133)
Namespace: biological_process
Definition: The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.
cell migration involved in mesendoderm migration (GO:0090134)
Namespace: biological_process
Definition: The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.
actin filament branching (GO:0090135)
Namespace: biological_process
Definition: The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.
epithelial cell-cell adhesion (GO:0090136)
Namespace: biological_process
Definition: The attachment of an epithelial cell to another epithelial cell via adhesion molecules.
obsolete epithelial cell-cell adhesion involved in epithelium migration (GO:0090137)
Namespace: biological_process
Definition: OBSOLETE. The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mitochondrial chromosome packaging (GO:0090139)
Namespace: biological_process
Definition: A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure.
Synonyms: mitochondrial DNA packaging
regulation of mitochondrial fission (GO:0090140)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
Synonyms: regulation of mitochondrial division
positive regulation of mitochondrial fission (GO:0090141)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
Synonyms: positive regulation of mitochondrial division