LiteFold/GO huggingface dataset:
platelet activating factor biosynthetic process (GO:0006663)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
Synonyms: PAF biosynthesis; PAF biosynthetic process; platelet activating factor anabolism; platelet activating factor biosynthesis; platelet activating factor formation; platelet activating factor synthesis
glycolipid metabolic process (GO:0006664)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.
Synonyms: glycolipid metabolism
sphingolipid metabolic process (GO:0006665)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
Synonyms: sphingolipid metabolism
3-keto-sphinganine metabolic process (GO:0006666)
Namespace: biological_process
Definition: The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
Synonyms: 3-keto-dihydrosphingosine metabolic process; 3-keto-dihydrosphingosine metabolism; 3-keto-sphinganine metabolism
sphinganine metabolic process (GO:0006667)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.
Synonyms: dihydrosphingosine metabolic process; dihydrosphingosine metabolism; sphinganine metabolism
sphinganine-1-phosphate metabolic process (GO:0006668)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
Synonyms: dihydrosphingosine-1-phosphate metabolic process; dihydrosphingosine-1-phosphate metabolism; sphinganine-1-phosphate metabolism
sphinganine-1-phosphate biosynthetic process (GO:0006669)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
Synonyms: dihydrosphingosine-1-phosphate biosynthesis; dihydrosphingosine-1-phosphate biosynthetic process; sphinganine-1-phosphate anabolism; sphinganine-1-phosphate biosynthesis; sphinganine-1-phosphate formation; sphinganine-1-phosphate synthesis
inositol phosphoceramide metabolic process (GO:0006673)
Namespace: biological_process
Definition: The chemical reactions and pathways involving inositol phosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.
Synonyms: inositol phosphorylceramide metabolic process; inositol phosphorylceramide metabolism; inositolphosphoceramide metabolism
mannosyl-inositol phosphorylceramide metabolic process (GO:0006675)
Namespace: biological_process
Definition: The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
Synonyms: mannose inositol phosphoceramide metabolic process; mannose inositol phosphoceramide metabolism; mannose-inositol-P-ceramide (MIPC) metabolic process; mannose-inositol-P-ceramide (MIPC) metabolism; mannosyl-inositol-phosphorylceramide metabolism; MIPC metabolic process; MIPC metabolism
mannosyl diphosphorylinositol ceramide metabolic process (GO:0006676)
Namespace: biological_process
Definition: The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.
Synonyms: M(IP)2C metabolic process; M(IP)2C metabolism; mannosyl diphosphorylinositol ceramide metabolism
glycosylceramide metabolic process (GO:0006677)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
Synonyms: glycosylceramide metabolism
glucosylceramide metabolic process (GO:0006678)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
Synonyms: glucosylceramide metabolism
glucosylceramide biosynthetic process (GO:0006679)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound composed of a ceramide backbone covalently linked to a glucose. The glucose can be further elongated with the sequential addition of various carbohydrate units.
Synonyms: glucosylceramide anabolism; glucosylceramide biosynthesis; glucosylceramide formation; glucosylceramide synthesis
glucosylceramide catabolic process (GO:0006680)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
Synonyms: glucosylceramide breakdown; glucosylceramide catabolism; glucosylceramide degradation
galactosylceramide metabolic process (GO:0006681)
Namespace: biological_process
Definition: The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
Synonyms: galactosylceramide metabolism
galactosylceramide catabolic process (GO:0006683)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
Synonyms: galactosylceramide breakdown; galactosylceramide catabolism; galactosylceramide degradation
sphingomyelin metabolic process (GO:0006684)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
Synonyms: sphingomyelin metabolism
sphingomyelin catabolic process (GO:0006685)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms: sphingomyelin breakdown; sphingomyelin catabolism; sphingomyelin degradation
sphingomyelin biosynthetic process (GO:0006686)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
Synonyms: sphingomyelin anabolism; sphingomyelin biosynthesis; sphingomyelin formation; sphingomyelin synthesis
glycosphingolipid metabolic process (GO:0006687)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
Synonyms: glycosphingolipid metabolism
glycosphingolipid biosynthetic process (GO:0006688)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a glycosphingolipid, a compound composed of a ceramide backbone covalently linked to at least one carbohydrate moiety.
Synonyms: glycosphingolipid anabolism; glycosphingolipid biosynthesis; glycosphingolipid formation; glycosphingolipid synthesis; glycosylceramide biosynthetic process
ganglioside catabolic process (GO:0006689)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
Synonyms: ganglioside breakdown; ganglioside catabolism; ganglioside degradation
icosanoid metabolic process (GO:0006690)
Namespace: biological_process
Definition: The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
Synonyms: eicosanoid metabolic process; eicosanoid metabolism; icosanoid metabolism
leukotriene metabolic process (GO:0006691)
Namespace: biological_process
Definition: The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
Synonyms: leukotriene metabolism
prostanoid metabolic process (GO:0006692)
Namespace: biological_process
Definition: The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.
Synonyms: prostanoid metabolism
prostaglandin metabolic process (GO:0006693)
Namespace: biological_process
Definition: The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
Synonyms: prostaglandin metabolism
steroid biosynthetic process (GO:0006694)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
Synonyms: steroid anabolism; steroid biosynthesis; steroid formation; steroid synthesis; steroidogenesis
cholesterol biosynthetic process (GO:0006695)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms: cholesterol anabolism; cholesterol biosynthesis; cholesterol formation; cholesterol synthesis
ergosterol biosynthetic process (GO:0006696)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
Synonyms: ergosterol anabolism; ergosterol biosynthesis; ergosterol formation; ergosterol synthesis
ecdysone biosynthetic process (GO:0006697)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
Synonyms: ecdysone anabolism; ecdysone biosynthesis; ecdysone formation; ecdysone synthesis
obsolete ecdysone modification (GO:0006698)
Namespace: biological_process
Definition: OBSOLETE. The covalent or conformational alteration of ecdysone, resulting in a change in its properties.
Synonyms: ecdysone modification
Comment: This term was made obsolete because it was created to cover the conversion of ecdysone to its active form ecdysterone (20-hydroxyecdysone), but this reaction is carried out in a single step by ecdysone 20-monooxygenase (EC:1.14.99.22) and so is a function rather than a process.
bile acid biosynthetic process (GO:0006699)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
Synonyms: bile acid anabolism; bile acid biosynthesis; bile acid formation; bile acid synthesis
progesterone biosynthetic process (GO:0006701)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
Synonyms: progesterone anabolism; progesterone biosynthesis; progesterone formation; progesterone synthesis
androgen biosynthetic process (GO:0006702)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
Synonyms: androgen anabolism; androgen biosynthesis; androgen formation; androgen synthesis
estrogen biosynthetic process (GO:0006703)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
Synonyms: estrogen anabolism; estrogen biosynthesis; estrogen formation; estrogen synthesis; oestrogen biosynthesis; oestrogen biosynthetic process
glucocorticoid biosynthetic process (GO:0006704)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms: glucocorticoid anabolism; glucocorticoid biosynthesis; glucocorticoid formation; glucocorticoid synthesis
mineralocorticoid biosynthetic process (GO:0006705)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms: mineralocorticoid anabolism; mineralocorticoid biosynthesis; mineralocorticoid formation; mineralocorticoid synthesis
steroid catabolic process (GO:0006706)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
Synonyms: steroid breakdown; steroid catabolism; steroid degradation
cholesterol catabolic process (GO:0006707)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
Synonyms: cholesterol breakdown; cholesterol catabolism; cholesterol degradation
ecdysone catabolic process (GO:0006708)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
Synonyms: ecdysone breakdown; ecdysone catabolism; ecdysone degradation
progesterone catabolic process (GO:0006709)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
Synonyms: progesterone breakdown; progesterone catabolism; progesterone degradation
androgen catabolic process (GO:0006710)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
Synonyms: androgen breakdown; androgen catabolism; androgen degradation
estrogen catabolic process (GO:0006711)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
Synonyms: estrogen breakdown; estrogen catabolism; estrogen degradation; oestrogen catabolic process; oestrogen catabolism
mineralocorticoid catabolic process (GO:0006712)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms: mineralocorticoid breakdown; mineralocorticoid catabolism; mineralocorticoid degradation
glucocorticoid catabolic process (GO:0006713)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
Synonyms: glucocorticoid breakdown; glucocorticoid catabolism; glucocorticoid degradation
sesquiterpenoid metabolic process (GO:0006714)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.
Synonyms: sesquiterpenoid metabolism
farnesol biosynthetic process (GO:0006715)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
Synonyms: farnesol anabolism; farnesol biosynthesis; farnesol formation; farnesol synthesis
juvenile hormone metabolic process (GO:0006716)
Namespace: biological_process
Definition: The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
Synonyms: juvenile hormone metabolism
obsolete juvenile hormone binding (GO:0006717)
Namespace: biological_process
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: juvenile hormone binding
Comment: This term was made obsolete because it represents a molecular function and not a biological process.
juvenile hormone biosynthetic process (GO:0006718)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
Synonyms: juvenile hormone anabolism; juvenile hormone biosynthesis; juvenile hormone formation; juvenile hormone synthesis
juvenile hormone catabolic process (GO:0006719)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
Synonyms: juvenile hormone breakdown; juvenile hormone catabolism; juvenile hormone degradation
isoprenoid metabolic process (GO:0006720)
Namespace: biological_process
Definition: The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
Synonyms: isoprenoid metabolism; polyisoprenoid metabolic process; polyisoprenoid metabolism; polyterpene metabolic process; polyterpene metabolism
terpenoid metabolic process (GO:0006721)
Namespace: biological_process
Definition: The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
Synonyms: terpenoid metabolism
cuticle hydrocarbon biosynthetic process (GO:0006723)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
Synonyms: cuticle hydrocarbon anabolism; cuticle hydrocarbon biosynthesis; cuticle hydrocarbon formation; cuticle hydrocarbon synthesis
eye pigment biosynthetic process (GO:0006726)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
Synonyms: eye pigment anabolism; eye pigment biosynthesis; eye pigment formation; eye pigment synthesis
ommochrome biosynthetic process (GO:0006727)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
Synonyms: ommochrome anabolism; ommochrome biosynthesis; ommochrome formation; ommochrome synthesis
pteridine biosynthetic process (GO:0006728)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
Synonyms: pteridine anabolism; pteridine biosynthesis; pteridine formation; pteridine synthesis; pterin biosynthesis; pterin biosynthetic process
tetrahydrobiopterin biosynthetic process (GO:0006729)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
Synonyms: 5,6,7,8-tetrahydrobiopterin biosynthetic process; tetrahydrobiopterin anabolism; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin formation; tetrahydrobiopterin synthesis
one-carbon metabolic process (GO:0006730)
Namespace: biological_process
Definition: The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
Synonyms: one carbon metabolic process; one carbon metabolism; one-carbon metabolism; one-carbon transfer metabolic process; one-carbon transfer metabolism
obsolete coenzyme and prosthetic group metabolic process (GO:0006731)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving coenzymes and prosthetic groups.
Synonyms: coenzyme and prosthetic group metabolic process
Comment: This term was made obsolete because it was replaced by more specific terms.
obsolete coenzyme metabolic process (GO:0006732)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
Synonyms: coenzyme and prosthetic group metabolic process; coenzyme and prosthetic group metabolism; coenzyme metabolism; group transfer coenzyme metabolic process; group transfer coenzyme metabolism
Comment: 1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.
obsolete oxidoreduction coenzyme metabolic process (GO:0006733)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.
Synonyms: oxidoreduction coenzyme metabolism
Comment: 1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group metabolic processes that are not all metabolically related by the fact that they may be used as a coenzyme.