LiteFold/GO huggingface dataset:
AMPA glutamate receptor complex (GO:0032281)
Namespace: cellular_component
Definition: An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
Synonyms: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; AMPA receptor; AMPA-selective glutamate receptor complex
plastid acetyl-CoA carboxylase complex (GO:0032282)
Namespace: cellular_component
Definition: An acetyl-CoA carboxylase complex located in the stroma of a plastid.
Synonyms: plastid ACCase complex
plastid acetate CoA-transferase complex (GO:0032283)
Namespace: cellular_component
Definition: An acetate CoA-transferase complex located in the stroma of a plastid.
obsolete plastid biotin carboxylase complex (GO:0032284)
Namespace: cellular_component
Definition: OBSOLETE. A biotin carboxylase complex located in the stroma of a plastid.
Comment: This term was obsoleted because it represents a homomer.
non-myelinated axon ensheathment (GO:0032285)
Namespace: biological_process
Definition: The process in which a non-myelinating glial cell membrane closes around an axon.
Synonyms: ensheathment of non-myelinated axons
central nervous system myelin maintenance (GO:0032286)
Namespace: biological_process
Definition: The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
Synonyms: central nervous system myelin sheath maintenance; myelin maintenance in central nervous system
peripheral nervous system myelin maintenance (GO:0032287)
Namespace: biological_process
Definition: The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
Synonyms: myelin maintenance in peripheral nervous system; peripheral nervous system myelin sheath maintenance
myelin assembly (GO:0032288)
Namespace: biological_process
Definition: The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
Synonyms: myelin formation; myelin sheath assembly
central nervous system myelin formation (GO:0032289)
Namespace: biological_process
Definition: The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
Synonyms: central nervous system myelin sheath formation; myelin formation in central nervous system
peripheral nervous system myelin formation (GO:0032290)
Namespace: biological_process
Definition: The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system.
Synonyms: myelin formation in peripheral nervous system; peripheral nervous system myelin sheath formation
axon ensheathment in central nervous system (GO:0032291)
Namespace: biological_process
Definition: The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.
Synonyms: ensheathment of axons in central nervous system
non-myelinated axon ensheathment in central nervous system (GO:0032293)
Namespace: biological_process
Definition: The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.
Synonyms: ensheathment of non-myelinated axons in central nervous system
peripheral nervous system non-myelinated axon ensheathment (GO:0032294)
Namespace: biological_process
Definition: The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.
Synonyms: ensheathment of non-myelinated axons in peripheral nervous system
ensheathment of neuronal cell bodies (GO:0032295)
Namespace: biological_process
Definition: The process in which satellite glial cells isolate neuronal cell bodies.
negative regulation of DNA-templated DNA replication initiation (GO:0032297)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
Synonyms: down regulation of DNA replication initiation; down-regulation of DNA replication initiation; downregulation of DNA replication initiation; inhibition of DNA replication initiation; negative regulation of DNA replication initiation; negative regulation of DNA-dependent DNA replication initiation
positive regulation of DNA-templated DNA replication initiation (GO:0032298)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.
Synonyms: activation of DNA replication initiation; negative regulation of DNA replication initiation; positive regulation of DNA-dependent DNA replication initiation; stimulation of DNA replication initiation; up regulation of DNA replication initiation; up-regulation of DNA replication initiation; upregulation of DNA replication initiation
ribonuclease H2 complex (GO:0032299)
Namespace: cellular_component
Definition: A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.
Synonyms: RNase H2 complex
mismatch repair complex (GO:0032300)
Namespace: cellular_component
Definition: Any complex formed of proteins that act in mismatch repair.
MutSalpha complex (GO:0032301)
Namespace: cellular_component
Definition: A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
Synonyms: MMR complex; MSH2/MSH6 complex
MutSbeta complex (GO:0032302)
Namespace: cellular_component
Definition: A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.
Synonyms: MMR complex; MSH2/MSH3 complex
regulation of icosanoid secretion (GO:0032303)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.
Synonyms: regulation of eicosanoid secretion
positive regulation of icosanoid secretion (GO:0032305)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.
Synonyms: activation of icosanoid secretion; positive regulation of eicosanoid secretion; stimulation of icosanoid secretion; up regulation of icosanoid secretion; up-regulation of icosanoid secretion; upregulation of icosanoid secretion
regulation of prostaglandin secretion (GO:0032306)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
Synonyms: regulation of prostacyclin secretion
negative regulation of prostaglandin secretion (GO:0032307)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
Synonyms: down regulation of prostaglandin secretion; down-regulation of prostaglandin secretion; downregulation of prostaglandin secretion; inhibition of prostaglandin secretion; negative regulation of prostacyclin secretion
positive regulation of prostaglandin secretion (GO:0032308)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
Synonyms: activation of prostaglandin secretion; positive regulation of prostacyclin secretion; stimulation of prostaglandin secretion; up regulation of prostaglandin secretion; up-regulation of prostaglandin secretion; upregulation of prostaglandin secretion
icosanoid secretion (GO:0032309)
Namespace: biological_process
Definition: The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.
Synonyms: eicosanoid secretion
prostaglandin secretion (GO:0032310)
Namespace: biological_process
Definition: The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
Synonyms: prostacyclin secretion
angiogenin-PRI complex (GO:0032311)
Namespace: cellular_component
Definition: A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.
Synonyms: angiogenin-placental ribonuclease inhibitor complex
ubiquinone catabolic process (GO:0032322)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.
Synonyms: ubiquinone breakdown; ubiquinone catabolism; ubiquinone degradation
lipoate catabolic process (GO:0032323)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lipoate.
Synonyms: lipoic acid breakdown; lipoic acid catabolism; lipoic acid degradation
molybdopterin cofactor biosynthetic process (GO:0032324)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms: molybdopterin cofactor anabolism; molybdopterin cofactor biosynthesis; molybdopterin cofactor formation; molybdopterin cofactor synthesis
molybdopterin cofactor catabolic process (GO:0032325)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
W-molybdopterin cofactor catabolic process (GO:0032327)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
Synonyms: Moco catabolic process; Moco catabolism; W-molybdopterin cofactor breakdown; W-molybdopterin cofactor catabolism; W-molybdopterin cofactor degradation
alanine transport (GO:0032328)
Namespace: biological_process
Definition: The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
serine transport (GO:0032329)
Namespace: biological_process
Definition: The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: serine import
regulation of chondrocyte differentiation (GO:0032330)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
negative regulation of chondrocyte differentiation (GO:0032331)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
Synonyms: down regulation of chondrocyte differentiation; down-regulation of chondrocyte differentiation; downregulation of chondrocyte differentiation; inhibition of chondrocyte differentiation
positive regulation of chondrocyte differentiation (GO:0032332)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
Synonyms: activation of chondrocyte differentiation; stimulation of chondrocyte differentiation; up regulation of chondrocyte differentiation; up-regulation of chondrocyte differentiation; upregulation of chondrocyte differentiation
activin secretion (GO:0032333)
Namespace: biological_process
Definition: The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
inhibin secretion (GO:0032334)
Namespace: biological_process
Definition: The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
regulation of activin secretion (GO:0032335)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.
negative regulation of activin secretion (GO:0032336)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.
Synonyms: down regulation of activin secretion; down-regulation of activin secretion; downregulation of activin secretion; inhibition of activin secretion
positive regulation of activin secretion (GO:0032337)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.
Synonyms: activation of activin secretion; stimulation of activin secretion; up regulation of activin secretion; up-regulation of activin secretion; upregulation of activin secretion
regulation of inhibin secretion (GO:0032338)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.
negative regulation of inhibin secretion (GO:0032339)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.
Synonyms: down regulation of inhibin secretion; down-regulation of inhibin secretion; downregulation of inhibin secretion; inhibition of inhibin secretion
aldosterone metabolic process (GO:0032341)
Namespace: biological_process
Definition: The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
Synonyms: aldosterone metabolism
aldosterone biosynthetic process (GO:0032342)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
regulation of aldosterone metabolic process (GO:0032344)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
Synonyms: regulation of aldosterone metabolism
obsolete positive regulation of aldosterone metabolic process (GO:0032346)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
Synonyms: activation of aldosterone metabolic process; positive regulation of aldosterone metabolism; stimulation of aldosterone metabolic process; up regulation of aldosterone metabolic process; up-regulation of aldosterone metabolic process; upregulation of aldosterone metabolic process
Comment: This term was obsoleted because it is an unnecessary grouping class.
regulation of aldosterone biosynthetic process (GO:0032347)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
positive regulation of aldosterone biosynthetic process (GO:0032349)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
Synonyms: activation of aldosterone biosynthetic process; stimulation of aldosterone biosynthetic process; up regulation of aldosterone biosynthetic process; up-regulation of aldosterone biosynthetic process; upregulation of aldosterone biosynthetic process
regulation of hormone metabolic process (GO:0032350)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
Synonyms: regulation of hormone metabolism
negative regulation of hormone metabolic process (GO:0032351)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
Synonyms: down regulation of hormone metabolic process; down-regulation of hormone metabolic process; downregulation of hormone metabolic process; inhibition of hormone metabolic process; negative regulation of hormone metabolism
positive regulation of hormone metabolic process (GO:0032352)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
Synonyms: activation of hormone metabolic process; positive regulation of hormone metabolism; stimulation of hormone metabolic process; up regulation of hormone metabolic process; up-regulation of hormone metabolic process; upregulation of hormone metabolic process
negative regulation of hormone biosynthetic process (GO:0032353)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
Synonyms: down regulation of hormone biosynthetic process; down-regulation of hormone biosynthetic process; downregulation of hormone biosynthetic process; inhibition of hormone biosynthetic process
response to follicle-stimulating hormone (GO:0032354)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
Synonyms: response to follicle stimulating hormone stimulus; response to follicle-stimulating hormone stimulus; response to FSH stimulus
response to estradiol (GO:0032355)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
Synonyms: response to E2 stimulus; response to estradiol stimulus
oxidized DNA binding (GO:0032356)
Namespace: molecular_function
Definition: Binding to a DNA region containing an oxidized residue.
Synonyms: oxidised DNA binding
oxidized purine DNA binding (GO:0032357)
Namespace: molecular_function
Definition: Binding to a DNA region containing an oxidized purine residue.
Synonyms: oxidised purine DNA binding; oxidized purine base DNA binding; oxidized purine nucleobase DNA binding
oxidized pyrimidine DNA binding (GO:0032358)
Namespace: molecular_function
Definition: Binding to a DNA region containing an oxidized pyrimidine residue.
Synonyms: oxidised pyrimidine DNA binding; oxidized pyrimidine base DNA binding; oxidized pyrimidine nucleobase DNA binding
provirus excision (GO:0032359)
Namespace: biological_process
Definition: The molecular events that lead to the excision of a viral genome from the host genome.
Synonyms: prophage excision
pyridoxal 5'-phosphate catabolic process (GO:0032361)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
obsolete FAD catabolic process (GO:0032362)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of FAD, the oxidized form of flavin-adenine dinucleotide.
Synonyms: FAD breakdown; FAD catabolism; FAD degradation; oxidized flavin adenine dinucleotide catabolic process
Comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.
FMN catabolic process (GO:0032363)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
intracellular oxygen homeostasis (GO:0032364)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell.
Synonyms: cellular oxygen homeostasis; oxygen homeostasis
intracellular lipid transport (GO:0032365)
Namespace: biological_process
Definition: The directed movement of lipids within cells.
intracellular sterol transport (GO:0032366)
Namespace: biological_process
Definition: The directed movement of sterols within cells.
intracellular cholesterol transport (GO:0032367)
Namespace: biological_process
Definition: The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
regulation of lipid transport (GO:0032368)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of lipid transport (GO:0032369)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: down regulation of lipid transport; down-regulation of lipid transport; downregulation of lipid transport; inhibition of lipid transport
positive regulation of lipid transport (GO:0032370)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: activation of lipid transport; stimulation of lipid transport; up regulation of lipid transport; up-regulation of lipid transport; upregulation of lipid transport
regulation of sterol transport (GO:0032371)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.