LiteFold/GO huggingface dataset:
regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070428)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
Synonyms: regulation of NOD1 signaling pathway; regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070429)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
Synonyms: negative regulation of NOD1 signaling pathway; negative regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070430)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
Synonyms: positive regulation of NOD1 signaling pathway; positive regulation of nucleotide-binding oligomerization domain containing 1 signalling pathway
nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070431)
Namespace: biological_process
Definition: The series of molecular signals initiated by the binding of a ligand (such as a bacterial peptidoglycan) to a cytoplasmic nucleotide-binding oligomerization domain containing 2 (NOD2) protein receptor, and ending with regulation of a downstream cellular process.
Synonyms: NOD2 signaling pathway; nucleotide-binding oligomerization domain containing 2 signalling pathway
regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070432)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
Synonyms: regulation of NOD2 signaling pathway; regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070433)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
Synonyms: negative regulation of NOD2 signaling pathway; negative regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070434)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
Synonyms: positive regulation of NOD2 signaling pathway; positive regulation of nucleotide-binding oligomerization domain containing 2 signalling pathway
Shc-EGFR complex (GO:0070435)
Namespace: cellular_component
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms: Shc-Egfr complex, EGF stimulated
Grb2-EGFR complex (GO:0070436)
Namespace: cellular_component
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.
Synonyms: Grb2-Egfr complex, EGF stimulated
obsolete mTOR-FKBP12-rapamycin complex (GO:0070438)
Namespace: cellular_component
Definition: OBSOLETE. A protein complex that contains the mTOR (mammalian target of rapamycin) serine/threonine kinase, the peptidyl-prolyl cis-trans isomerase FKBP12 (FKBP1A) and rapamycin (sirolimus).
Synonyms: Fkbp1a-Frap1 complex; mTOR-FKBP12-rapamycin complex
Comment: This term was made obsolete because it describes a complex with a drug bound, with the drug being exogenous to the species where the experiment takes place and where that interaction would never occur naturally.
Mad-Max-mSin3A complex (GO:0070439)
Namespace: cellular_component
Definition: A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.
Mad-Max-mSin3B complex (GO:0070440)
Namespace: cellular_component
Definition: A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.
G-protein beta/gamma-Btk complex (GO:0070441)
Namespace: cellular_component
Definition: A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.
Synonyms: G protein complex (BTK, GNG1, GNG2); G protein complex (Btk, Gng2, Gnb1)
Comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.
integrin alphaIIb-beta3 complex (GO:0070442)
Namespace: cellular_component
Definition: An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.
Synonyms: alphaIIb-beta3 integrin complex; ITGA2B-ITGB3 complex
Mad-Max complex (GO:0070443)
Namespace: cellular_component
Definition: A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.
oligodendrocyte progenitor proliferation (GO:0070444)
Namespace: biological_process
Definition: The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.
Synonyms: oligodendrocyte precursor proliferation
regulation of oligodendrocyte progenitor proliferation (GO:0070445)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.
Synonyms: regulation of oligodendrocyte precursor proliferation
negative regulation of oligodendrocyte progenitor proliferation (GO:0070446)
Namespace: biological_process
Definition: Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.
Synonyms: negative regulation of oligodendrocyte precursor proliferation
positive regulation of oligodendrocyte progenitor proliferation (GO:0070447)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.
Synonyms: positive regulation of oligodendrocyte precursor proliferation
laricitrin 5'-O-methyltransferase activity (GO:0070448)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.
Synonyms: CrCOMT2; flavonoid 3',5'-O-dimethyltransferase activity; S-adenosyl-L-methionine:myricetin O-methyltransferase activity
interleukin4-interleukin-4 receptor complex (GO:0070450)
Namespace: cellular_component
Definition: A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.
Synonyms: IL4-IL4 receptor complex; IL4-IL4R-IL2RG complex
cell hair (GO:0070451)
Namespace: cellular_component
Definition: A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.
Synonyms: imaginal disc-derived wing hair; non-sensory hair
positive regulation of ergosterol biosynthetic process (GO:0070452)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
Synonyms: activation of ergosterol biosynthetic process; positive regulation of ergosterol anabolism; positive regulation of ergosterol biosynthesis; positive regulation of ergosterol formation; positive regulation of ergosterol synthesis; stimulation of ergosterol biosynthetic process; up regulation of ergosterol biosynthetic process; up-regulation of ergosterol biosynthetic process; upregulation of ergosterol biosynthetic process
regulation of heme biosynthetic process (GO:0070453)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
Synonyms: regulation of haem biosynthesis; regulation of haem biosynthetic process; regulation of heme anabolism; regulation of heme biosynthesis; regulation of heme formation; regulation of heme synthesis
negative regulation of heme biosynthetic process (GO:0070454)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
Synonyms: down regulation of heme biosynthetic process; down-regulation of heme biosynthetic process; downregulation of heme biosynthetic process; inhibition of heme biosynthetic process; negative regulation of haem biosynthetic process; negative regulation of heme anabolism; negative regulation of heme biosynthesis; negative regulation of heme formation; negative regulation of heme synthesis
positive regulation of heme biosynthetic process (GO:0070455)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
Synonyms: activation of heme biosynthetic process; positive regulation of haem biosynthetic process; positive regulation of heme anabolism; positive regulation of heme biosynthesis; positive regulation of heme formation; positive regulation of heme synthesis; stimulation of heme biosynthetic process; up regulation of heme biosynthetic process; up-regulation of heme biosynthetic process; upregulation of heme biosynthetic process
galactose-1-phosphate phosphatase activity (GO:0070456)
Namespace: molecular_function
Definition: Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.
D-galactose-1-phosphate phosphatase activity (GO:0070457)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.
cellular detoxification of nitrogen compound (GO:0070458)
Namespace: biological_process
Definition: Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
Synonyms: cellular detoxification of nitrogenous compound
thyroid-stimulating hormone secretion (GO:0070460)
Namespace: biological_process
Definition: The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.
Synonyms: thyroid stimulating hormone secretion; TSH secretion
SAGA-type complex (GO:0070461)
Namespace: cellular_component
Definition: A histone acetyltransferase complex that acetylates nucleosomal histones H2B, H3, or H4 and is required for the expression of a subset of Pol II-transcribed genes. This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs).
Synonyms: SAGA family complex
plus-end specific microtubule depolymerization (GO:0070462)
Namespace: biological_process
Definition: The removal of tubulin heterodimers from the plus end of a microtubule.
tubulin-dependent ATPase activity (GO:0070463)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.
Synonyms: tubulin-activated ATPase activity
alphav-beta3 integrin-collagen alpha3(VI) complex (GO:0070464)
Namespace: cellular_component
Definition: A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.
alpha2-beta1 integrin-alpha3(VI) complex (GO:0070466)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
Synonyms: ITGA2-ITGB1-COL6A3 complex
RC-1 DNA recombination complex (GO:0070467)
Namespace: cellular_component
Definition: A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.
Synonyms: DNA recombination complex RC-1; RC-1 complex (recombination complex 1)
dentin extracellular matrix secretion (GO:0070468)
Namespace: biological_process
Definition: The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.
Synonyms: dentin secretion; dentine secretion; predentin secretion
obsolete respirasome (GO:0070469)
Namespace: cellular_component
Definition: OBSOLETE. The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
Synonyms: membrane electron transport chain; respiratory chain
Comment: The reason for obsoletion is that this term is equivalent to respiratory chain complex.
obsolete plasma membrane respirasome (GO:0070470)
Namespace: cellular_component
Definition: OBSOLETE. A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
Synonyms: plasma membrane electron transport chain; plasma membrane respiratory chain
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
uterine smooth muscle contraction (GO:0070471)
Namespace: biological_process
Definition: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.
Synonyms: myometrial contraction; myometrial smooth muscle contraction; myometrium contraction
regulation of uterine smooth muscle contraction (GO:0070472)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.
Synonyms: regulation of myometrial contraction; regulation of myometrial smooth muscle contraction; regulation of myometrium contraction
negative regulation of uterine smooth muscle contraction (GO:0070473)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.
Synonyms: down regulation of uterine smooth muscle contraction; down-regulation of uterine smooth muscle contraction; downregulation of uterine smooth muscle contraction; inhibition of uterine smooth muscle contraction; negative regulation of myometrial contraction; negative regulation of myometrial smooth muscle contraction; negative regulation of myometrium contraction; uterine smooth muscle relaxation
positive regulation of uterine smooth muscle contraction (GO:0070474)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.
Synonyms: activation of uterine smooth muscle contraction; positive regulation of myometrial contraction; positive regulation of myometrial smooth muscle contraction; positive regulation of myometrium contraction; stimulation of uterine smooth muscle contraction; up regulation of uterine smooth muscle contraction; up-regulation of uterine smooth muscle contraction; upregulation of uterine smooth muscle contraction
rRNA base methylation (GO:0070475)
Namespace: biological_process
Definition: The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
rRNA (guanine-N7)-methylation (GO:0070476)
Namespace: biological_process
Definition: The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
endospore core (GO:0070477)
Namespace: cellular_component
Definition: An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
Synonyms: 3'-5' NMD; 3'-5' nonsense-mediated decay; 3'-5' nonsense-mediated mRNA decay; nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay; nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay; nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay (GO:0070479)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.
Synonyms: 5'-3' NMD; 5'-3' nonsense-mediated decay; 5'-3' nonsense-mediated mRNA decay; nuclear-transcribed mRNA breakdown, 5'-3' exonucleolytic nonsense-mediated decay; nuclear-transcribed mRNA catabolism, 5'-3' exonucleolytic nonsense-mediated decay; nuclear-transcribed mRNA degradation, 5'-3' exonucleolytic nonsense-mediated decay
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay (GO:0070480)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
nuclear-transcribed mRNA catabolic process, non-stop decay (GO:0070481)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
Synonyms: non-stop decay; non-stop mRNA decay; nonstop mRNA decay; nuclear-transcribed mRNA breakdown, non-stop decay; nuclear-transcribed mRNA catabolism, non-stop decay; nuclear-transcribed mRNA degradation, non-stop decay
response to oxygen levels (GO:0070482)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
detection of hypoxia (GO:0070483)
Namespace: biological_process
Definition: The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
Synonyms: detection of reduced oxygen levels
obsolete dehydro-D-arabinono-1,4-lactone metabolic process (GO:0070484)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
Synonyms: dehydro-D-arabinono-1,4-lactone metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
dehydro-D-arabinono-1,4-lactone biosynthetic process (GO:0070485)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
Synonyms: dehydro-D-arabinono-1,4-lactone anabolism; dehydro-D-arabinono-1,4-lactone biosynthesis; dehydro-D-arabinono-1,4-lactone formation; dehydro-D-arabinono-1,4-lactone synthesis
monocyte aggregation (GO:0070487)
Namespace: biological_process
Definition: The adhesion of one monocyte to one or more other monocytes via adhesion molecules.
Synonyms: mononuclear phagocyte aggregation
neutrophil aggregation (GO:0070488)
Namespace: biological_process
Definition: The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.
Synonyms: neutrocyte aggregation; neutrophil leucocyte aggregation; neutrophil leukocyte aggregation; neutrophilic leucocyte aggregation; neutrophilic leukocyte aggregation
T cell aggregation (GO:0070489)
Namespace: biological_process
Definition: The adhesion of one T cell to one or more other T cells via adhesion molecules.
Synonyms: T lymphocyte aggregation; T-cell aggregation; T-lymphocyte aggregation
protein pupylation (GO:0070490)
Namespace: biological_process
Definition: The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxy-terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.
Synonyms: Pup-protein conjugation; pupylation
oligosaccharide binding (GO:0070492)
Namespace: molecular_function
Definition: Binding to an oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
thrombin-activated receptor signaling pathway (GO:0070493)
Namespace: biological_process
Definition: A G protein-coupled receptor signaling pathway initiated by thrombin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
Synonyms: thrombin receptor signaling pathway; thrombin receptor signalling pathway
negative regulation of thrombin-activated receptor signaling pathway (GO:0070495)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
Synonyms: negative regulation of thrombin receptor signaling pathway; negative regulation of thrombin receptor signalling pathway