LiteFold/GO huggingface dataset:
obsolete proton-transporting ATP synthase complex, coupling factor F(o) (GO:0045263)
Namespace: cellular_component
Definition: OBSOLETE. All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.
Synonyms: hydrogen-transporting ATP synthase complex, coupling factor F(o); hydrogen-transporting ATP synthase, coupling factor CF(0); hydrogen-transporting ATP synthase, F0 sector; proton-transporting ATP synthase complex, coupling factor F(0)
Comment: The reason for obsoletion is that this term represents a subcomplex that does not perform a distinct function.
obsolete plasma membrane proton-transporting ATP synthase complex, coupling factor F(o) (GO:0045264)
Namespace: cellular_component
Definition: OBSOLETE. All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.
Synonyms: hydrogen-transporting ATP synthase, F0 sector; proton-transporting ATP synthase complex, coupling factor F(0); proton-transporting ATP synthase complex, coupling factor F(o)
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
obsolete proton-transporting ATP synthase, stator stalk (GO:0045265)
Namespace: cellular_component
Definition: OBSOLETE. One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.
Synonyms: hydrogen-transporting ATP synthase, stator stalk
Comment: The reason for obsoletion is that this term represents a subcomplex that does not perform a distinct function.
obsolete plasma membrane proton-transporting ATP synthase, stator stalk (GO:0045266)
Namespace: cellular_component
Definition: OBSOLETE. One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species.
Synonyms: hydrogen-transporting ATP synthase, stator stalk; proton-transporting ATP synthase, stator stalk
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
obsolete proton-transporting ATP synthase, catalytic core (GO:0045267)
Namespace: cellular_component
Definition: OBSOLETE. The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
Synonyms: hydrogen-transporting ATP synthase, catalytic core
Comment: The reason for obsoletion is that this term represents a subcomplex that does not perform a distinct function.
obsolete plasma membrane proton-transporting ATP synthase, catalytic core (GO:0045268)
Namespace: cellular_component
Definition: OBSOLETE. The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species.
Synonyms: hydrogen-transporting ATP synthase, catalytic core; proton-transporting ATP synthase, catalytic core
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
obsolete proton-transporting ATP synthase, central stalk (GO:0045269)
Namespace: cellular_component
Definition: OBSOLETE. One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.
Synonyms: hydrogen-transporting ATP synthase, central stalk
Comment: The reason for obsoletion is that this term represents a subcomplex that does not perform a distinct function.
obsolete plasma membrane proton-transporting ATP synthase, central stalk (GO:0045270)
Namespace: cellular_component
Definition: OBSOLETE. One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species.
Synonyms: hydrogen-transporting ATP synthase, central stalk; proton-transporting ATP synthase, central stalk
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
respiratory chain complex I (GO:0045271)
Namespace: cellular_component
Definition: Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.
Synonyms: electron transport complex I; NADH dehydrogenase (ubiquinone) complex; NADH dehydrogenase complex (ubiquinone); NADH-Q oxidoreductase complex
Comment: Note that this term represents a location and not a function; the activity possessed by this complex is mentioned in the definition for the purpose of describing and distinguishing the complex. The function possessed by this complex is represented by the molecular function term 'NADH dehydrogenase (ubiquinone) activity ; GO:0008137'.
obsolete plasma membrane respiratory chain complex I (GO:0045272)
Namespace: cellular_component
Definition: OBSOLETE. A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.
Synonyms: NADH dehydrogenase (ubiquinone) complex; respiratory chain complex I
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
respiratory chain complex II (succinate dehydrogenase) (GO:0045273)
Namespace: cellular_component
Definition: A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
Synonyms: electron transport complex II
respiratory chain complex III (GO:0045275)
Namespace: cellular_component
Definition: A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
Synonyms: coenzyme Q-cytochrome c oxidoreductase complex; coenzyme Q-cytochrome c reductase complex; complex III; CoQH2-cytochrome c reductase complex; cytochrome bc(1) complex; cytochrome bc1 complex; electron transport complex III; ubiquinol-cytochrome c oxidoreductase complex; ubiquinol-cytochrome-c reductase complex
obsolete plasma membrane respiratory chain complex III (GO:0045276)
Namespace: cellular_component
Definition: OBSOLETE. A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species.
Synonyms: plasma membrane coenzyme Q-cytochrome c oxidoreductase complex; plasma membrane coenzyme Q-cytochrome c reductase complex; plasma membrane cytochrome bc1 complex; plasma membrane ubiquinol-cytochrome-c reductase complex; respiratory chain complex III; ubiquinol-cytochrome c oxidoreductase complex; ubiquinol-cytochrome-c reductase complex
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
respiratory chain complex IV (GO:0045277)
Namespace: cellular_component
Definition: A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
Synonyms: cytochrome c oxidase complex; electron transport complex IV
obsolete plasma membrane respiratory chain complex IV (GO:0045278)
Namespace: cellular_component
Definition: OBSOLETE. A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species.
Synonyms: cytochrome c oxidase complex; respiratory chain complex IV
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
obsolete succinate dehydrogenase complex (GO:0045281)
Namespace: cellular_component
Definition: OBSOLETE. A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
obsolete plasma membrane succinate dehydrogenase complex (GO:0045282)
Namespace: cellular_component
Definition: OBSOLETE. A multimeric complex which consists of flavoprotein (subunit A ; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species.
Synonyms: succinate dehydrogenase complex
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
fumarate reductase complex (GO:0045283)
Namespace: cellular_component
Definition: A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)).
Comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.
obsolete plasma membrane fumarate reductase complex (GO:0045284)
Namespace: cellular_component
Definition: OBSOLETE. A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.
Synonyms: fumarate reductase complex
Comment: See also the molecular function term 'succinate dehydrogenase (ubiquinone) activity ; GO:0008177'.\nThe reason for obsoletion is that this term unnecssarily specified a cellular compartment.
D-arabinose 1-dehydrogenase [NAD(P)+] activity (GO:0045290)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.
Synonyms: D-arabinose:NAD(P)+ 1-oxidoreductase activity
mRNA trans splicing, SL addition (GO:0045291)
Namespace: biological_process
Definition: The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.
Synonyms: nuclear mRNA trans splicing, SL addition; nuclear mRNA trans splicing, spliced leader addition
mRNA cis splicing, via spliceosome (GO:0045292)
Namespace: biological_process
Definition: The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
Synonyms: nuclear mRNA cis splicing, via spliceosome; nuclear mRNA cis splicing, via U2-type spliceosome; splicing
mRNA editing complex (GO:0045293)
Namespace: cellular_component
Definition: A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.
Synonyms: editosome
alpha-catenin binding (GO:0045294)
Namespace: molecular_function
Definition: Binding to catenin complex alpha subunit.
cadherin binding (GO:0045296)
Namespace: molecular_function
Definition: Binding to cadherin, a type I membrane protein involved in cell adhesion.
obsolete post-mating behavior (GO:0045297)
Namespace: biological_process
Definition: OBSOLETE. The specific behavior of an organism following mating.
Synonyms: post-mating behaviour
Comment: This term was obsoleted because it was not precisely defined.
tubulin complex (GO:0045298)
Namespace: cellular_component
Definition: A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.
otolith mineralization (GO:0045299)
Namespace: biological_process
Definition: The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.
stearoyl-[ACP] desaturase activity (GO:0045300)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 H+ + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] = (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin].
Synonyms: acyl-[acyl-carrier-protein] desaturase activity; acyl-acyl-carrier-protein desaturase activity; acyl-acyl-carrier-protein, hydrogen-donor:oxygen oxidoreductase activity; stearyl acyl carrier protein desaturase activity; stearyl-ACP desaturase activity
tRNA 2-(methylsulfanyl)-N(6)-isopentenyladenosine(37) hydroxylase activity (GO:0045301)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + acceptor-H2 + O2 = N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA + acceptor + H2O.
Synonyms: 2-methylthio-cis-ribozeatin hydroxylase activity; tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity; tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyladenosine)-hydroxylase activity; tRNA-(ms2io6A)-hydroxylase activity
choloylglycine hydrolase activity (GO:0045302)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
Synonyms: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-oylglycine amidohydrolase activity; bile salt hydrolase activity; choloyltaurine hydrolase activity; glycocholase activity
L-2,4-diaminobutyrate:2-oxoglutarate transaminase activity (GO:0045303)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-2,4-diaminobutanoate + 2-oxoglutarate = L-aspartate 4-semialdehyde + L-glutamate.
Synonyms: 2,4-diaminobutyrate 4-aminotransferase activity; DAB aminotransferase activity; DABA aminotransferase activity; diaminibutyric acid aminotransferase activity; diaminobutyrate transaminase activity; diaminobutyrate--2-oxoglutarate aminotransferase activity; diaminobutyrate-2-oxoglutarate transaminase activity; EctB; L-2,4-diaminobutanoate:2-oxoglutarate 4-aminotransferase activity; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase activity; L-2,4-diaminobutyrate:2-oxoglutarate 4-aminotransferase activity
obsolete regulator of establishment of competence for transformation activity (GO:0045305)
Namespace: molecular_function
Definition: OBSOLETE. Functions to either promote or inhibit the establishment of competence for transformation.
Synonyms: regulator of establishment of competence for transformation activity
Comment: This term was made obsolete because it does not represent a true function.
obsolete inhibitor of the establishment of competence for transformation activity (GO:0045306)
Namespace: molecular_function
Definition: OBSOLETE. Inhibits the establishment of competence for transformation.
Synonyms: inhibitor of the establishment of competence for transformation activity
Comment: This term was made obsolete because it does not represent a true function.
protein phosphorylated amino acid binding (GO:0045309)
Namespace: molecular_function
Definition: Binding to a phosphorylated amino acid residue within a protein.
Synonyms: phosphoprotein amino acid binding
obsolete phosphoserine/phosphothreonine binding (GO:0045310)
Namespace: molecular_function
Definition: OBSOLETE. Interacting selectively with a phosphorylated serine or threonine residue within a protein.
Synonyms: phosphoserine/phosphothreonine binding
Comment: This term was made obsolete because it represents two functions.
invasive growth in response to pheromone (GO:0045311)
Namespace: biological_process
Definition: The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.
nor-spermidine biosynthetic process (GO:0045312)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
Synonyms: nor-spermidine anabolism; nor-spermidine biosynthesis; nor-spermidine formation; nor-spermidine synthesis
rhabdomere membrane biogenesis (GO:0045313)
Namespace: biological_process
Definition: A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.
regulation of compound eye photoreceptor development (GO:0045314)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.
Synonyms: regulation of eye photoreceptor development
positive regulation of compound eye photoreceptor development (GO:0045315)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.
Synonyms: activation of eye photoreceptor development; positive regulation of eye photoreceptor development; stimulation of eye photoreceptor development; up regulation of eye photoreceptor development; up-regulation of eye photoreceptor development; upregulation of eye photoreceptor development
negative regulation of compound eye photoreceptor development (GO:0045316)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.
Synonyms: down regulation of eye photoreceptor development; down-regulation of eye photoreceptor development; downregulation of eye photoreceptor development; inhibition of eye photoreceptor development; negative regulation of eye photoreceptor development
equator specification (GO:0045317)
Namespace: biological_process
Definition: The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
obsolete SRP-independent cotranslational protein-membrane targeting, translocation (GO:0045319)
Namespace: biological_process
Definition: OBSOLETE. The process during cotranslational membrane targeting wherein proteins move across a membrane. This process is independent of SRP and signal recognition.
Synonyms: SRP-independent cotranslational membrane targeting, translocation; SRP-independent cotranslational protein-membrane targeting, translocation
Comment: This term was made obsolete because there is no evidence for the existence of this process.
obsolete chloroplast proton-transporting ATP synthase complex (GO:0045320)
Namespace: cellular_component
Definition: OBSOLETE. A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.
Synonyms: chloroplast hydrogen-translocating F-type ATPase complex; chloroplast proton-transporting F-type ATPase complex; hydrogen-translocating F-type ATPase complex
Comment: The reason for obsoletion is that this term unnecssarily specified a cellular compartment.
leukocyte activation (GO:0045321)
Namespace: biological_process
Definition: A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
Synonyms: immune cell activation; leucocyte activation
unmethylated CpG binding (GO:0045322)
Namespace: molecular_function
Definition: Binding to uan nmethylated CpG motif. Unmethylated CpG dinucleotides are often associated with gene promoters.
interleukin-1 receptor complex (GO:0045323)
Namespace: cellular_component
Definition: A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.
Synonyms: IL-1 receptor complex
obsolete peptidyl-tryptophan hydroxylation (GO:0045325)
Namespace: biological_process
Definition: OBSOLETE. The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.
Comment: This term was obsoleted because it represents a molecular function.
obsolete protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine (GO:0045326)
Namespace: biological_process
Definition: OBSOLETE. The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.
Synonyms: DNA-protein covalent cross-linking via the 3'-end to peptidyl-tyrosine
Comment: The reason for obsoletion is that is not known to be catalyzed by any gene product.
obsolete cytochrome P450 4A1-heme linkage (GO:0045328)
Namespace: biological_process
Definition: OBSOLETE. The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.
Synonyms: cytochrome P450 4A1-haem linkage
Comment: This term was obsoleted because it represents a molecular function.
carnitine biosynthetic process (GO:0045329)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
Synonyms: carnitine anabolism; carnitine biosynthesis; carnitine formation; carnitine synthesis; vitamin Bt biosynthesis; vitamin Bt biosynthetic process
obsolete aspartyl esterase activity (GO:0045330)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.
Comment: This term was obsoleted because it does not correspond to a precise activity.