LiteFold/GO huggingface dataset:
activin complex (GO:0048180)
Namespace: cellular_component
Definition: A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.
Comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.
activin AB complex (GO:0048183)
Namespace: cellular_component
Definition: A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.
Synonyms: inhibin beta-A; inhibin beta-B
Comment: Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and a inhibin alpha subunit. See 'inhibin complex ; GO:0043511'.
obsolete follistatin binding (GO:0048184)
Namespace: molecular_function
Definition: OBSOLETE. Binding to the peptide hormone follistatin.
Synonyms: follistatin binding
Comment: This term was made obsolete because it represents binding to an individual protein.
activin binding (GO:0048185)
Namespace: molecular_function
Definition: Binding to activin, a dimer of inhibin-beta subunits.
Set1C/COMPASS complex (GO:0048188)
Namespace: cellular_component
Definition: A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
Synonyms: COMPASS complex; Set1/COMPASS complex; Set1C
Lid2 complex (GO:0048189)
Namespace: cellular_component
Definition: A protein complex involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid2, Ash2, Jmj3, Snt2, and Sdc1.
wing disc dorsal/ventral pattern formation (GO:0048190)
Namespace: biological_process
Definition: The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
Synonyms: wing disc dorsal-ventral pattern formation; wing disc dorsoventral pattern formation
obsolete peptide stabilization activity (GO:0048191)
Namespace: molecular_function
Definition: OBSOLETE. Strengthening of a bond between peptides. Peptides are compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
Synonyms: peptide stabilization activity
Comment: This term was made obsolete because it represents a biological process.
obsolete peptide antigen stabilization activity (GO:0048192)
Namespace: molecular_function
Definition: OBSOLETE. Strengthening of a bond with a peptide antigen; a fragment of a foreign protein derived by proteolysis within the cell.
Synonyms: peptide antigen stabilization activity
Comment: This term was made obsolete because it represents a biological process.
Golgi vesicle transport (GO:0048193)
Namespace: biological_process
Definition: The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
Synonyms: Golgi-derived vesicle transport
Golgi vesicle budding (GO:0048194)
Namespace: biological_process
Definition: The evagination of the Golgi membrane, resulting in formation of a vesicle.
Synonyms: dictyosome vesicle budding; Golgi-derived vesicle budding
Golgi membrane priming complex assembly (GO:0048195)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.
Synonyms: formation of dictyosome membrane priming complex; formation of Golgi membrane priming complex
obsolete plant extracellular matrix (GO:0048196)
Namespace: cellular_component
Definition: OBSOLETE. The matrix external to the plant plasma membrane, composed of the cell wall and middle lamella.
Synonyms: middle lamella-containing extracellular matrix; plant extracellular matrix
Comment: Note that this term does not have 'extracellular region ; GO:0005576' as a parent because in plants the extracellular matrix is considered part of the cell.
Golgi membrane coat protein complex assembly (GO:0048197)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.
Synonyms: dictyosome membrane binding by cytosolic coat proteins; dictyosome membrane bud coat oligomerisation; Golgi apparatus membrane coat protein complex assembly; Golgi membrane bud coat oligomerisation
Golgi vesicle bud deformation and release (GO:0048198)
Namespace: biological_process
Definition: The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.
Synonyms: dictyosome vesicle bud deformation; Golgi-derived vesicle bud deformation and release
vesicle targeting, to, from or within Golgi (GO:0048199)
Namespace: biological_process
Definition: The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
Synonyms: dictyosome vesicle targeting; Golgi vesicle targeting; vesicle targeting, to, from or within dictyosome
Golgi transport vesicle coating (GO:0048200)
Namespace: biological_process
Definition: The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.
Synonyms: dictyosome transport vesicle coating
vesicle targeting, plasma membrane to endosome (GO:0048201)
Namespace: biological_process
Definition: The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
Synonyms: plasma membrane to endosome targeting
clathrin coating of Golgi vesicle (GO:0048202)
Namespace: biological_process
Definition: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
Synonyms: clathrin coating of Golgi-derived vesicle
vesicle targeting, trans-Golgi to endosome (GO:0048203)
Namespace: biological_process
Definition: The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.
Synonyms: trans-Golgi to endosome targeting
vesicle targeting, inter-Golgi cisterna (GO:0048204)
Namespace: biological_process
Definition: The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.
Synonyms: inter-Golgi cisterna targeting
COPI coating of Golgi vesicle (GO:0048205)
Namespace: biological_process
Definition: The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
Synonyms: COPI coating of Golgi-derived vesicle; COPI vesicle coating
vesicle targeting, cis-Golgi to rough endoplasmic reticulum (GO:0048206)
Namespace: biological_process
Definition: The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.
Synonyms: cis-Golgi to rough endoplasmic reticulum targeting; cis-Golgi to rough ER targeting; vesicle targeting, cis-Golgi to rough ER
vesicle targeting, rough ER to cis-Golgi (GO:0048207)
Namespace: biological_process
Definition: The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.
Synonyms: rough endoplasmic reticulum to cis-Golgi targeting; rough ER to cis-Golgi targeting; vesicle targeting, rough endoplasmic reticulum to cis-Golgi
COPII vesicle coating (GO:0048208)
Namespace: biological_process
Definition: The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
Synonyms: COPII coating of ER-derived vesicle; COPII vesicle coat assembly; COPII vesicle coat formation
regulation of vesicle targeting, to, from or within Golgi (GO:0048209)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
Synonyms: regulation of Golgi vesicle targeting
Golgi vesicle fusion to target membrane (GO:0048210)
Namespace: biological_process
Definition: The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.
Synonyms: dictyosome vesicle fusion to target membrane; Golgi-derived vesicle fusion to target membrane
Golgi vesicle docking (GO:0048211)
Namespace: biological_process
Definition: The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.
Synonyms: dictyosome vesicle docking to target membrane; Golgi vesicle docking with target membrane; Golgi vesicle to membrane docking; Golgi-derived vesicle docking
Golgi vesicle uncoating (GO:0048212)
Namespace: biological_process
Definition: The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.
Synonyms: dictyosome vesicle coat depolymerization; Golgi vesicle coat depolymerization; Golgi vesicle coat protein depolymerization; Golgi-derived vesicle uncoating
obsolete Golgi vesicle prefusion complex stabilization (GO:0048213)
Namespace: biological_process
Definition: OBSOLETE. The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.
Synonyms: dictyosome vesicle prefusion complex stabilisation; Golgi vesicle prefusion complex assembly; Golgi-derived vesicle prefusion complex stabilization
Comment: The reason for obsoletion is that it is too specific and there is no evidence for a Golgi vesicle prefusion complex.
regulation of Golgi vesicle fusion to target membrane (GO:0048214)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.
Comment: Note that GTP-binding Rab proteins serve as regulators of vesicle targeting and fusion.
positive regulation of Golgi vesicle fusion to target membrane (GO:0048215)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.
Synonyms: activation of Golgi vesicle fusion to target membrane; stimulation of Golgi vesicle fusion to target membrane; up regulation of Golgi vesicle fusion to target membrane; up-regulation of Golgi vesicle fusion to target membrane; upregulation of Golgi vesicle fusion to target membrane
negative regulation of Golgi vesicle fusion to target membrane (GO:0048216)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.
Synonyms: down regulation of Golgi vesicle fusion to target membrane; down-regulation of Golgi vesicle fusion to target membrane; downregulation of Golgi vesicle fusion to target membrane; inhibition of Golgi vesicle fusion to target membrane
pectic matrix (GO:0048217)
Namespace: cellular_component
Definition: The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.
inter-Golgi cisterna vesicle-mediated transport (GO:0048219)
Namespace: biological_process
Definition: The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.
Synonyms: inter-Golgi cisterna transport
glycoprotein network (GO:0048222)
Namespace: cellular_component
Definition: An extracellular matrix part that consists of cross-linked glycoproteins.
Synonyms: extensin
hemicellulose network (GO:0048223)
Namespace: cellular_component
Definition: Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.
lignin network (GO:0048224)
Namespace: cellular_component
Definition: An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.
suberin network (GO:0048225)
Namespace: cellular_component
Definition: An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.
Casparian strip (GO:0048226)
Namespace: cellular_component
Definition: Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.
plasma membrane to endosome transport (GO:0048227)
Namespace: biological_process
Definition: Transport of a vesicle from the plasma membrane to the endosome.
obsolete actin cortical patch distribution (GO:0048228)
Namespace: biological_process
Definition: OBSOLETE. Any process that establishes the spatial arrangement of actin cortical patches. An actin cortical patch is a discrete actin-containing structure found at the plasma membrane in fungal cells.
Synonyms: actin cortical patch distribution
Comment: This term was made obsolete because its definition is very similar to that of its parent term, actin cortical patch localization (GO:0051666), but somewhat unclear, and not similar enough to merge the terms.
gametophyte development (GO:0048229)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.
Synonyms: gametogenesis
male gamete generation (GO:0048232)
Namespace: biological_process
Definition: Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
pollen sperm cell differentiation (GO:0048235)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
Synonyms: male gamete generation; male gametophyte sperm cell differentiation; sperm cell differentiation
plant-type sporogenesis (GO:0048236)
Namespace: biological_process
Definition: The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.
Synonyms: plant spore formation
rough endoplasmic reticulum lumen (GO:0048237)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of the rough endoplasmic reticulum.
Synonyms: RER lumen; rough ER lumen
smooth endoplasmic reticulum lumen (GO:0048238)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of the smooth endoplasmic reticulum.
Synonyms: SER lumen; smooth ER lumen
negative regulation of DNA recombination at telomere (GO:0048239)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.
Synonyms: down regulation of telomeric recombination at telomere; down-regulation of telomeric recombination at telomere; downregulation of telomeric recombination at telomere; inhibition of telomeric recombination at telomere; negative regulation of telomeric recombination at telomere; suppression of telomeric recombination at telomere
sperm capacitation (GO:0048240)
Namespace: biological_process
Definition: A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
Synonyms: sperm activation
Comment: Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract.
epinephrine transport (GO:0048241)
Namespace: biological_process
Definition: The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: adrenaline transport
epinephrine secretion (GO:0048242)
Namespace: biological_process
Definition: The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
Synonyms: adrenaline secretion
norepinephrine secretion (GO:0048243)
Namespace: biological_process
Definition: The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
Synonyms: noradrenaline secretion
phytanoyl-CoA dioxygenase activity (GO:0048244)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate.
Synonyms: phytanoyl-CoA 2 oxoglutarate dioxygenase activity; phytanoyl-CoA 2-hydroxylase activity; phytanoyl-CoA alpha-hydroxylase activity; phytanoyl-CoA hydroxylase activity; phytanoyl-CoA, 2-oxoglutarate:oxygen oxidoreductase (2-hydroxylating)
eosinophil chemotaxis (GO:0048245)
Namespace: biological_process
Definition: The movement of an eosinophil in response to an external stimulus.
macrophage chemotaxis (GO:0048246)
Namespace: biological_process
Definition: The movement of a macrophage in response to an external stimulus.
lymphocyte chemotaxis (GO:0048247)
Namespace: biological_process
Definition: The directed movement of a lymphocyte in response to an external stimulus.
CXCR3 chemokine receptor binding (GO:0048248)
Namespace: molecular_function
Definition: Binding to a CXCR3 chemokine receptor.
high-affinity phosphate transmembrane transporter activity (GO:0048249)
Namespace: molecular_function
Definition: Enables the transfer of phosphate from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
Synonyms: high affinity phosphate transmembrane transporter activity
iron import into the mitochondrion (GO:0048250)
Namespace: biological_process
Definition: The process in which iron is transported from the cytosol into the mitochondrial matrix.
Synonyms: mitochondrial iron cation transmembrane transport; mitochondrial iron ion transmembrane transport; mitochondrial iron ion transport; mitochondrial iron transport
snoRNA localization (GO:0048254)
Namespace: biological_process
Definition: Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.
Synonyms: establishment and maintenance of snoRNA localization; small nucleolar RNA localization; snoRNA localisation
mRNA stabilization (GO:0048255)
Namespace: biological_process
Definition: Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
flap endonuclease activity (GO:0048256)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.
3'-flap endonuclease activity (GO:0048257)
Namespace: molecular_function
Definition: Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.
Synonyms: 3' flap endonuclease activity
obsolete 3-ketoglucose-reductase activity (GO:0048258)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.
Comment: This term was obsoleted because it represents a specific substrate.
regulation of receptor-mediated endocytosis (GO:0048259)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms: regulation of receptor mediated endocytosis
positive regulation of receptor-mediated endocytosis (GO:0048260)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms: activation of receptor mediated endocytosis; positive regulation of receptor mediated endocytosis; stimulation of receptor mediated endocytosis; up regulation of receptor mediated endocytosis; up-regulation of receptor mediated endocytosis; upregulation of receptor mediated endocytosis
negative regulation of receptor-mediated endocytosis (GO:0048261)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
Synonyms: down regulation of receptor mediated endocytosis; down-regulation of receptor mediated endocytosis; downregulation of receptor mediated endocytosis; inhibition of receptor mediated endocytosis; negative regulation of receptor mediated endocytosis