LiteFold/GO huggingface dataset:
negative regulation of T cell mediated cytotoxicity (GO:0001915)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.
Synonyms: down regulation of T cell mediated cytotoxicity; down-regulation of T cell mediated cytotoxicity; downregulation of T cell mediated cytotoxicity; inhibition of T cell mediated cytotoxicity; negative regulation of T cell mediated apoptosis; negative regulation of T cell mediated cell death; negative regulation of T cell mediated cell killing; negative regulation of T cell mediated cytolysis; negative regulation of T lymphocyte mediated cytotoxicity; negative regulation of T-cell mediated apoptosis; negative regulation of T-cell mediated cell death; negative regulation of T-cell mediated cell killing; negative regulation of T-cell mediated cytolysis; negative regulation of T-cell mediated cytotoxicity; negative regulation of T-lymphocyte mediated cytotoxicity
positive regulation of T cell mediated cytotoxicity (GO:0001916)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.
Synonyms: activation of T cell mediated cytotoxicity; positive regulation of T cell mediated apoptosis; positive regulation of T cell mediated cell death; positive regulation of T cell mediated cell killing; positive regulation of T cell mediated cytolysis; positive regulation of T lymphocyte mediated cytotoxicity; positive regulation of T-cell mediated apoptosis; positive regulation of T-cell mediated cell death; positive regulation of T-cell mediated cell killing; positive regulation of T-cell mediated cytolysis; positive regulation of T-cell mediated cytotoxicity; positive regulation of T-lymphocyte mediated cytotoxicity; stimulation of T cell mediated cytotoxicity; up regulation of T cell mediated cytotoxicity; up-regulation of T cell mediated cytotoxicity; upregulation of T cell mediated cytotoxicity
photoreceptor inner segment (GO:0001917)
Namespace: cellular_component
Definition: The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
farnesylated protein binding (GO:0001918)
Namespace: molecular_function
Definition: Binding to a farnesylated protein.
regulation of receptor recycling (GO:0001919)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of receptor recycling.
negative regulation of receptor recycling (GO:0001920)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate of receptor recycling.
Synonyms: down regulation of receptor recycling; down-regulation of receptor recycling; downregulation of receptor recycling; inhibition of receptor recycling
positive regulation of receptor recycling (GO:0001921)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of receptor recycling.
Synonyms: activation of receptor recycling; stimulation of receptor recycling; up regulation of receptor recycling; up-regulation of receptor recycling; upregulation of receptor recycling
B-1 B cell homeostasis (GO:0001922)
Namespace: biological_process
Definition: The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
Synonyms: B-1 B lymphocyte homeostasis; B-1 B-cell homeostasis; B-1 B-lymphocyte homeostasis
Comment: Note that this term represents the return of B-1 B cell levels to stable numbers following an immune response, as well as the proliferation and elimination of B-1 B cells in a organism required to maintain stable numbers in the absence of an outside stimulus.
regulation of B-1 B cell differentiation (GO:0001924)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
Synonyms: regulation of B-1 B cell development; regulation of B-1 B lymphocyte differentiation; regulation of B-1 B-cell differentiation; regulation of B-1 B-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative regulation of B-1 B cell differentiation (GO:0001925)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.
Synonyms: down regulation of B-1 B cell differentiation; down-regulation of B-1 B cell differentiation; downregulation of B-1 B cell differentiation; inhibition of B-1 B cell differentiation; negative regulation of B-1 B cell development; negative regulation of B-1 B lymphocyte differentiation; negative regulation of B-1 B-cell differentiation; negative regulation of B-1 B-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of B-1 B cell differentiation (GO:0001926)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.
Synonyms: activation of B-1 B cell differentiation; positive regulation of B-1 B cell development; positive regulation of B-1 B lymphocyte differentiation; positive regulation of B-1 B-cell differentiation; positive regulation of B-1 B-lymphocyte differentiation; stimulation of B-1 B cell differentiation; up regulation of B-1 B cell differentiation; up-regulation of B-1 B cell differentiation; upregulation of B-1 B cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
exocyst assembly (GO:0001927)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.
regulation of exocyst assembly (GO:0001928)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of exocyst assembly.
Comment: Note that the assembly is regulated by several small GTPases of the Rab and Rho families.
positive regulation of exocyst assembly (GO:0001930)
Namespace: biological_process
Definition: Any process that increases the rate or extent of exocyst assembly.
Synonyms: activation of exocyst assembly; stimulation of exocyst assembly; up regulation of exocyst assembly; up-regulation of exocyst assembly; upregulation of exocyst assembly
uropod (GO:0001931)
Namespace: cellular_component
Definition: A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
Synonyms: distal pole complex; retractile pole; uropodium
regulation of protein phosphorylation (GO:0001932)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
Synonyms: regulation of protein amino acid phosphorylation
negative regulation of protein phosphorylation (GO:0001933)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
Synonyms: down regulation of protein amino acid phosphorylation; down-regulation of protein amino acid phosphorylation; downregulation of protein amino acid phosphorylation; inhibition of protein amino acid phosphorylation; negative regulation of protein amino acid phosphorylation
positive regulation of protein phosphorylation (GO:0001934)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
Synonyms: activation of protein amino acid phosphorylation; positive regulation of protein amino acid phosphorylation; stimulation of protein amino acid phosphorylation; up regulation of protein amino acid phosphorylation; up-regulation of protein amino acid phosphorylation; upregulation of protein amino acid phosphorylation
endothelial cell proliferation (GO:0001935)
Namespace: biological_process
Definition: The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
negative regulation of endothelial cell proliferation (GO:0001937)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
Synonyms: down regulation of endothelial cell proliferation; down-regulation of endothelial cell proliferation; downregulation of endothelial cell proliferation; inhibition of endothelial cell proliferation
positive regulation of endothelial cell proliferation (GO:0001938)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of endothelial cell proliferation.
Synonyms: activation of endothelial cell proliferation; stimulation of endothelial cell proliferation; up regulation of endothelial cell proliferation; up-regulation of endothelial cell proliferation; upregulation of endothelial cell proliferation
male pronucleus (GO:0001940)
Namespace: cellular_component
Definition: The pronucleus originating from the spermatozoa that was involved in fertilization.
postsynaptic membrane organization (GO:0001941)
Namespace: biological_process
Definition: A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
Synonyms: post-synaptic membrane organization; postsynaptic membrane organisation
hair follicle development (GO:0001942)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
vasculature development (GO:0001944)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
Synonyms: vascular system development
lymph vessel development (GO:0001945)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
lymphangiogenesis (GO:0001946)
Namespace: biological_process
Definition: Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
Synonyms: lymph vessel formation
heart looping (GO:0001947)
Namespace: biological_process
Definition: The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceding septation.
Synonyms: cardiac looping
sebaceous gland cell differentiation (GO:0001949)
Namespace: biological_process
Definition: The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
Synonyms: sebocytes differentiation
obsolete plasma membrane enriched fraction (GO:0001950)
Namespace: cellular_component
Definition: OBSOLETE. The fraction of cells, prepared by disruptive biochemical methods, that is enriched for plasma membranes.
Synonyms: plasma membrane enriched fraction; PME fraction
Comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.
intestinal D-glucose absorption (GO:0001951)
Namespace: biological_process
Definition: Uptake of D-glucose into the blood by absorption from the small intestine.
negative regulation of cell-matrix adhesion (GO:0001953)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
Synonyms: down regulation of cell-matrix adhesion; down-regulation of cell-matrix adhesion; downregulation of cell-matrix adhesion; inhibition of cell-matrix adhesion
positive regulation of cell-matrix adhesion (GO:0001954)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
Synonyms: activation of cell-matrix adhesion; stimulation of cell-matrix adhesion; up regulation of cell-matrix adhesion; up-regulation of cell-matrix adhesion; upregulation of cell-matrix adhesion
blood vessel maturation (GO:0001955)
Namespace: biological_process
Definition: A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.
positive regulation of neurotransmitter secretion (GO:0001956)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.
Synonyms: activation of neurotransmitter secretion; stimulation of neurotransmitter secretion; up regulation of neurotransmitter secretion; up-regulation of neurotransmitter secretion; upregulation of neurotransmitter secretion
intramembranous ossification (GO:0001957)
Namespace: biological_process
Definition: Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
Synonyms: dermal ossification; intramembranous bone ossification
Comment: An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.
regulation of cytokine-mediated signaling pathway (GO:0001959)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
Synonyms: regulation of cytokine and chemokine mediated signaling pathway; regulation of cytokine mediated signaling pathway; regulation of cytokine mediated signalling pathway
negative regulation of cytokine-mediated signaling pathway (GO:0001960)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
Synonyms: down regulation of cytokine mediated signaling pathway; down-regulation of cytokine mediated signaling pathway; downregulation of cytokine mediated signaling pathway; inhibition of cytokine mediated signaling pathway; negative regulation of cytokine and chemokine mediated signaling pathway; negative regulation of cytokine mediated signaling pathway; negative regulation of cytokine mediated signalling pathway
positive regulation of cytokine-mediated signaling pathway (GO:0001961)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
Synonyms: activation of cytokine mediated signaling pathway; positive regulation of cytokine and chemokine mediated signaling pathway; positive regulation of cytokine mediated signaling pathway; positive regulation of cytokine mediated signalling pathway; stimulation of cytokine mediated signaling pathway; up regulation of cytokine mediated signaling pathway; up-regulation of cytokine mediated signaling pathway; upregulation of cytokine mediated signaling pathway
alpha-1,3-galactosyltransferase activity (GO:0001962)
Namespace: molecular_function
Definition: Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
Synonyms: isoglobotriaosylceramide synthase
synaptic transmission, dopaminergic (GO:0001963)
Namespace: biological_process
Definition: The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
Synonyms: dopaminergic synaptic transmission
G-protein alpha-subunit binding (GO:0001965)
Namespace: molecular_function
Definition: Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
Synonyms: G-alpha protein subunit binding
thigmotaxis (GO:0001966)
Namespace: biological_process
Definition: The directed movement of an organism along a spatial gradient of mechanical contact with solid surfaces, typically manifested as a preference for maintaining proximity to walls, edges, or boundaries.
Synonyms: taxis in response to mechanical stimulus; taxis in response to touch stimulus; thigmotactic behavior; wall-following behavior
Comment: In behavioral neuroscience, thigmotaxis commonly refers to the tendency of animals to remain close to walls or edges when placed in an open arena, often used as an index of anxiety-related behavior. This is observed across taxa including rodents, fish, insects, and nematodes. The behavior is mediated by mechanosensory pathways and in some contexts involves dopaminergic signaling.
suckling behavior (GO:0001967)
Namespace: biological_process
Definition: Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
Synonyms: nursing behavior
positive regulation of activation of membrane attack complex (GO:0001970)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms: activation of activation of membrane attack complex; positive regulation of activation of MAC; positive regulation of activation of TCC; positive regulation of activation of terminal complement complex; positive regulation of activation of the terminal complement cascade; positive regulation of MAC assembly; positive regulation of MAC formation; positive regulation of membrane attack complex assembly; positive regulation of membrane attack complex formation; stimulation of activation of membrane attack complex; up regulation of activation of membrane attack complex; up-regulation of activation of membrane attack complex; upregulation of activation of membrane attack complex
negative regulation of activation of membrane attack complex (GO:0001971)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms: down regulation of activation of membrane attack complex; down-regulation of activation of membrane attack complex; downregulation of activation of membrane attack complex; inhibition of activation of membrane attack complex; negative regulation of activation of MAC; negative regulation of activation of TCC; negative regulation of activation of terminal complement complex; negative regulation of activation of the terminal complement cascade; negative regulation of MAC assembly; negative regulation of MAC formation; negative regulation of membrane attack complex assembly; negative regulation of membrane attack complex formation
retinoic acid binding (GO:0001972)
Namespace: molecular_function
Definition: Binding to retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
G protein-coupled adenosine receptor signaling pathway (GO:0001973)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
Synonyms: adenosine receptor signaling pathway; adenosine receptor signaling pathway, G-protein coupled; adenosine receptor signalling pathway; P1 receptor signaling pathway
blood vessel remodeling (GO:0001974)
Namespace: biological_process
Definition: The reorganization or renovation of existing blood vessels.
Synonyms: blood vessel remodelling
response to amphetamine (GO:0001975)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
nervous system process involved in regulation of systemic arterial blood pressure (GO:0001976)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by detection of stimuli and a neurological response.
Synonyms: blood pressure regulation by neurological process; fast control of arterial pressure; neurological process involved in regulation of systemic arterial blood pressure; neurological system process involved in regulation of systemic arterial blood pressure
obsolete renal system process involved in regulation of blood volume (GO:0001977)
Namespace: biological_process
Definition: OBSOLETE. A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.
Synonyms: renal blood volume control of blood pressure; renal regulation of blood volume
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback (GO:0001978)
Namespace: biological_process
Definition: The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.
Synonyms: baroreceptor feedback control of blood pressure; baroreceptor pressure buffer system; carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure
regulation of systemic arterial blood pressure by chemoreceptor signaling (GO:0001979)
Namespace: biological_process
Definition: The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
Synonyms: chemoreceptor control of blood pressure; chemoreceptor regulation of systemic arterial blood pressure; regulation of systemic arterial blood pressure by chemoreceptor signalling
baroreceptor detection of arterial stretch (GO:0001981)
Namespace: biological_process
Definition: The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.