LiteFold/GO huggingface dataset:
pentacyclic triterpenoid biosynthetic process (GO:0019745)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
Synonyms: pentacyclic triterpenoid anabolism; pentacyclic triterpenoid biosynthesis; pentacyclic triterpenoid formation; pentacyclic triterpenoid synthesis
hopanoid biosynthetic process (GO:0019746)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
Synonyms: hopanoid anabolism; hopanoid biosynthesis; hopanoid formation; hopanoid synthesis
regulation of isoprenoid metabolic process (GO:0019747)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.
Synonyms: regulation of isoprenoid metabolism
secondary metabolic process (GO:0019748)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
Synonyms: secondary metabolism; secondary metabolite metabolic process; secondary metabolite metabolism
cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte (GO:0019749)
Namespace: biological_process
Definition: The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.
chloroplast localization (GO:0019750)
Namespace: biological_process
Definition: Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.
Synonyms: chloroplast localisation
polyol metabolic process (GO:0019751)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
Synonyms: polyhydric alcohol metabolic process; polyol metabolism
carboxylic acid metabolic process (GO:0019752)
Namespace: biological_process
Definition: The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
Synonyms: carboxylic acid metabolism
one-carbon compound transport (GO:0019755)
Namespace: biological_process
Definition: The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: one carbon compound transport
cyanogenic glycoside biosynthetic process (GO:0019756)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
Synonyms: cyanogenic glycoside anabolism; cyanogenic glycoside biosynthesis; cyanogenic glycoside formation; cyanogenic glycoside synthesis
obsolete glycosinolate metabolic process (GO:0019757)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
Synonyms: glycosinolate metabolism
Comment: The reason for obsoletion is that this term was an unnecessary grouping term for glucosinolate.
obsolete glycosinolate biosynthetic process (GO:0019758)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
Synonyms: glycosinolate anabolism; glycosinolate biosynthesis; glycosinolate formation; glycosinolate synthesis
Comment: The reason for obsoletion is that this term was an unnecessary grouping term for glucosinolate.
obsolete glycosinolate catabolic process (GO:0019759)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
Synonyms: glycosinolate breakdown; glycosinolate catabolism; glycosinolate degradation
Comment: The reason for obsoletion is that this term was an unnecessary grouping term for glucosinolate.
glucosinolate metabolic process (GO:0019760)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
Synonyms: glucosinolate metabolism
glucosinolate biosynthetic process (GO:0019761)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
Synonyms: glucosinolate anabolism; glucosinolate biosynthesis; glucosinolate formation; glucosinolate synthesis
glucosinolate catabolic process (GO:0019762)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
Synonyms: glucosinolate breakdown; glucosinolate catabolism; glucosinolate degradation
immunoglobulin receptor activity (GO:0019763)
Namespace: molecular_function
Definition: Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: FC receptor activity
obsolete high affinity Fc receptor activity (GO:0019764)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: high affinity Fc receptor activity
Comment: This term was made obsolete because it is an unnecessary grouping term.
obsolete low affinity Fc receptor activity (GO:0019765)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: low affinity Fc receptor activity
Comment: This term was made obsolete because it is undefined and is an unnecessary grouping term.
IgA receptor activity (GO:0019766)
Namespace: molecular_function
Definition: Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
IgE receptor activity (GO:0019767)
Namespace: molecular_function
Definition: Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
low-affinity IgE receptor activity (GO:0019769)
Namespace: molecular_function
Definition: Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: low affinity Fc receptor activity; low affinity IgE receptor activity
IgG receptor activity (GO:0019770)
Namespace: molecular_function
Definition: Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
high-affinity IgG receptor activity (GO:0019771)
Namespace: molecular_function
Definition: Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: high affinity Fc receptor activity; high affinity IgG receptor activity
low-affinity IgG receptor activity (GO:0019772)
Namespace: molecular_function
Definition: Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: low affinity Fc receptor activity; low affinity IgG receptor activity
proteasome core complex, alpha-subunit complex (GO:0019773)
Namespace: cellular_component
Definition: The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.
proteasome core complex, beta-subunit complex (GO:0019774)
Namespace: cellular_component
Definition: The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.
FAT10 transferase activity (GO:0019775)
Namespace: molecular_function
Definition: Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.
Synonyms: FAT10 conjugating enzyme activity
Atg8-family ligase activity (GO:0019776)
Namespace: molecular_function
Definition: Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 family modifier to phosphatidylethanolamine or phosphatidylserine on a membrane.
Synonyms: APG8 ligase activity; Atg8 ligase activity; Atg8-like ligase activity
Atg12 activating enzyme activity (GO:0019778)
Namespace: molecular_function
Definition: Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
Synonyms: APG12 activating enzyme activity
Atg8 activating enzyme activity (GO:0019779)
Namespace: molecular_function
Definition: Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
Synonyms: APG7; APG8 activating enzyme activity
FAT10 activating enzyme activity (GO:0019780)
Namespace: molecular_function
Definition: Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.
ISG15 activating enzyme activity (GO:0019782)
Namespace: molecular_function
Definition: Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
Synonyms: UBE1L
ubiquitin-like protein peptidase activity (GO:0019783)
Namespace: molecular_function
Definition: An isopeptidase activity that cleaves ubiquitin or ubiquitin-like proteins (ULP; e.g. ATG8, ISG15, NEDD8, SUMO) from target proteins.
Synonyms: small conjugating protein-specific isopeptidase activity; small conjugating protein-specific protease activity; ubiquitin-like hydrolase activity; ubiquitin-like protein-specific isopeptidase activity; ubiquitin-like protein-specific protease activity; ubiquitin-like specific protease activity; ubiquitin-like-protein-specific protease activity; ubiquitin-specific protease activity involved in negative regulation of ERAD pathway; ubiquitin-specific protease activity involved in positive regulation of ERAD pathway; ubiquitinyl-like hydrolase activity
Comment: While ubiquitin-like proteins can be rarely linked to substrates via bonds other than isopeptide bonds, all known ubiquitin-like peptidases cleave the isopeptide bond.
deNEDDylase activity (GO:0019784)
Namespace: molecular_function
Definition: An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.
Synonyms: NEDD8-specific protease activity
ISG15-specific peptidase activity (GO:0019785)
Namespace: molecular_function
Definition: A thiol-dependent isopeptidase activity that cleaves ISG15 from a target protein to which it is conjugated.
Synonyms: ISG15-specific protease activity
protein-phosphatidylethanolamide deconjugating activity (GO:0019786)
Namespace: molecular_function
Definition: Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue.
Synonyms: APG8-PE hydrolase; APG8-specific protease activity; ATG8-PE deconjugation activity; ATG8-PE hydrolase activity; Atg8-specific peptidase activity; Atg8-specific protease activity
ubiquitin-like protein transferase activity (GO:0019787)
Namespace: molecular_function
Definition: Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
Synonyms: E2; E3; small conjugating protein ligase activity; small conjugating protein transferase activity; small protein conjugating enzyme activity; ubiquitin-like conjugating enzyme activity; ubiquitin-like-protein ligase activity
NEDD8 transferase activity (GO:0019788)
Namespace: molecular_function
Definition: Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y = Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.
Synonyms: Hub1 conjugating enzyme activity; NEDD8 conjugating enzyme activity; RUB1 conjugating enzyme activity
obsolete ubiquitin-like hydrolase activity (GO:0019790)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: ubiquitin-like hydrolase activity
Comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.
obsolete FAT10 hydrolase activity (GO:0019791)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: FAT10 hydrolase activity
Comment: This term was made obsolete because it cannot be determined what its intended meaning was, because the term name is not found in the literature.
obsolete ISG15 carrier activity (GO:0019793)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of ISG15 (interferon-stimulated gene-15) from one side of the membrane to the other.
Synonyms: interferon-stimulated gene-15 carrier activity; ISG15 carrier activity
Comment: This term was made obsolete because it is gene product-specific.
obsolete nonprotein amino acid biosynthetic process (GO:0019795)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of any amino acid that does not normally occur as a constituent residue of proteins.
Synonyms: nonprotein amino acid anabolism; nonprotein amino acid biosynthesis; nonprotein amino acid biosynthetic process; nonprotein amino acid formation; nonprotein amino acid synthesis
Comment: This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.
obsolete nonprotein amino acid catabolic process (GO:0019796)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of any amino acid not found, or rarely found, in peptide linkage in proteins.
Synonyms: nonprotein amino acid breakdown; nonprotein amino acid catabolic process; nonprotein amino acid catabolism; nonprotein amino acid degradation
Comment: This term was made obsolete because it was a grouping term that was poorly defined and did not provide a particularly meaningful grouping, since even for those amino acids commonly found in proteins, not all molecules necessarily end up incorporated into proteins. The term also violated the principle of positivity.
procollagen-proline 3-dioxygenase activity (GO:0019797)
Namespace: molecular_function
Definition: Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.
Synonyms: procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity; procollagen-proline,2-oxoglutarate 3-dioxygenase activity; proline,2-oxoglutarate 3-dioxygenase activity; prolyl 3-hydroxylase activity; prolyl-4-hydroxyprolyl-glycyl-peptide, 2-oxoglutarate: oxygen oxidoreductase, 3-hydroxylating activity; protocollagen proline 3-hydroxylase activity
procollagen-proline dioxygenase activity (GO:0019798)
Namespace: molecular_function
Definition: Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.
tubulin N-acetyltransferase activity (GO:0019799)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine. In most organisms it acetylates L-lysine at position 40 of alpha- tubulin.
Synonyms: acetyl-CoA:alpha-tubulin-L-lysine 6-N-acetyltransferase activity; acetyl-CoA:alpha-tubulin-L-lysine N6-acetyltransferase activity; acetyl-CoA:alpha-tubulin-lysine N-acetyltransferase activity; alpha-tubulin acetylase activity; alpha-tubulin acetyltransferase activity; alpha-tubulin N-acetyltransferase activity; TAT activity; tubulin acetyltransferase activity
obsolete peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)
Namespace: biological_process
Definition: OBSOLETE. The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.
Synonyms: peptide cross-linking via chondroitin 4-sulphate glycosaminoglycan
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined.
obsolete cyclization of asparagine involved in intein-mediated protein splicing (GO:0019801)
Namespace: biological_process
Definition: OBSOLETE. The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.
Synonyms: cyclization of asparagine, during protein splicing
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete cyclization of glutamine involved in intein-mediated protein splicing (GO:0019802)
Namespace: biological_process
Definition: OBSOLETE. The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.
Synonyms: cyclization of glutamine, during protein splicing
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete peptidyl-aspartic acid carboxylation (GO:0019803)
Namespace: biological_process
Definition: OBSOLETE. The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid.
Comment: This term was obsoleted because it represents a molecular function.
obsolete quinolinate synthetase complex (GO:0019804)
Namespace: cellular_component
Definition: OBSOLETE. A heterodimer which acts as a quinolinate synthetase; quinolinate synthetase B (L-aspartate oxidase) catalyzes the oxidation of L-aspartate to L-iminoaspartate; quinolinate synthetase A condenses L-imidoaspartate and dihydroxyacetone to quinolinate.
Synonyms: quinolinate synthetase complex
Comment: This term was made obsolete because there is no evidence that a physical complex forms; although the phrase "quinolinate synthetase complex" is occasionally used in the literature, it refers to two enzymes that act as monomers.
quinolinate biosynthetic process (GO:0019805)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
Synonyms: quinolinate anabolism; quinolinate biosynthesis; quinolinate formation; quinolinate synthesis
bromide peroxidase activity (GO:0019806)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.
Synonyms: bromoperoxidase activity
aspartoacylase activity (GO:0019807)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.
Synonyms: acetyl-aspartic deaminase activity; acylase II; aminoacylase II activity; N-acetylaspartate amidohydrolase activity; N-acyl-L-aspartate amidohydrolase activity
spermidine binding (GO:0019809)
Namespace: molecular_function
Definition: Binding to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
putrescine binding (GO:0019810)
Namespace: molecular_function
Definition: Binding to putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
cocaine binding (GO:0019811)
Namespace: molecular_function
Definition: Binding to cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.
type I site-specific deoxyribonuclease complex (GO:0019812)
Namespace: cellular_component
Definition: A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
Synonyms: type I restriction enzyme complex
type III site-specific deoxyribonuclease complex (GO:0019813)
Namespace: cellular_component
Definition: A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
Synonyms: type III restriction enzyme complex
immunoglobulin complex (GO:0019814)
Namespace: cellular_component
Definition: A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
Synonyms: antibody
Comment: Note that an immunoglobulin complex has the function of antigen binding if a suitable antigen is available.