LiteFold/GO huggingface dataset:
melibiose transmembrane transporter activity (GO:0015156)
Namespace: molecular_function
Definition: Enables the transfer of melibiose from one side of a membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.
raffinose transmembrane transporter activity (GO:0015158)
Namespace: molecular_function
Definition: Enables the transfer of raffinose from one side of a membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
Synonyms: raffinose permease
polysaccharide transmembrane transporter activity (GO:0015159)
Namespace: molecular_function
Definition: Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
beta-glucan transmembrane transporter activity (GO:0015160)
Namespace: molecular_function
Definition: Enables the transfer of beta-glucans from one side of a membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
lipid III floppase activity (GO:0015161)
Namespace: molecular_function
Definition: Enables the transbilayer of capsular-polysaccharides (Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III)) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of ECA. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.
Synonyms: capsular polysaccharide transmembrane transporter activity; capsule polysaccharide transporter activity; undecaprenol-pyrophosphate O-antigen flippase activity
glucuronoside transmembrane transporter activity (GO:0015164)
Namespace: molecular_function
Definition: Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
Synonyms: glucuronide transporter activity
polyol transmembrane transporter activity (GO:0015166)
Namespace: molecular_function
Definition: Enables the transfer of a polyol from one side of a membrane to the other. A polyol is any polyhydric alcohol.
Synonyms: sugar/polyol channel activity
arabitol transmembrane transporter activity (GO:0015167)
Namespace: molecular_function
Definition: Enables the transfer of an arabitol from one side of a membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
Synonyms: arabinitol transporter activity
glycerol transmembrane transporter activity (GO:0015168)
Namespace: molecular_function
Definition: Enables the transfer of glycerol from one side of a membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
glycerol-3-phosphate transmembrane transporter activity (GO:0015169)
Namespace: molecular_function
Definition: Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.
obsolete propanediol transmembrane transporter activity (GO:0015170)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
amino acid transmembrane transporter activity (GO:0015171)
Namespace: molecular_function
Definition: Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
Synonyms: amino acid permease activity; amino acid transporter activity; amino acid/choline transmembrane transporter activity; general amino acid permease activity; hydroxy/aromatic amino acid permease activity
acidic amino acid transmembrane transporter activity (GO:0015172)
Namespace: molecular_function
Definition: Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3.
Synonyms: acidic amino acid transporter activity
aromatic amino acid transmembrane transporter activity (GO:0015173)
Namespace: molecular_function
Definition: Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.
Synonyms: aromatic amino acid transporter activity; hydroxy/aromatic amino acid permease activity; valine/tyrosine/tryptophan permease activity
basic amino acid transmembrane transporter activity (GO:0015174)
Namespace: molecular_function
Definition: Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have side chains with a positive charge at pH 7.3.
Synonyms: basic amino acid permease activity; basic amino acid transporter activity; cationic amino acid transmembrane transporter activity
neutral L-amino acid transmembrane transporter activity (GO:0015175)
Namespace: molecular_function
Definition: Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3.
Synonyms: neutral amino acid transmembrane transporter activity; neutral amino acid transporter activity
obsolete holin (GO:0015176)
Namespace: molecular_function
Definition: OBSOLETE. Primary function of holins appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall of bacteria, where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some catalyze export of nucleases.
Synonyms: holin
Comment: This term was made obsolete because it represents a class of gene products.
L-amino acid transmembrane transporter activity (GO:0015179)
Namespace: molecular_function
Definition: Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
Synonyms: L-amino acid transporter activity
L-alanine transmembrane transporter activity (GO:0015180)
Namespace: molecular_function
Definition: Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.
Synonyms: L-alanine transporter activity
L-asparagine transmembrane transporter activity (GO:0015182)
Namespace: molecular_function
Definition: Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.
Synonyms: asparagine/glutamine permease activity; L-asparagine transporter activity
L-aspartate transmembrane transporter activity (GO:0015183)
Namespace: molecular_function
Definition: Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.
Synonyms: glutamate/aspartate porter activity; glutamate/aspartate:sodium symporter activity; L-aspartate transporter activity
gamma-aminobutyric acid transmembrane transporter activity (GO:0015185)
Namespace: molecular_function
Definition: Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).
Synonyms: 4-aminobutanoate transporter activity; 4-aminobutyrate transporter activity; betaine/GABA:sodium symporter activity; GABA transporter activity
L-glutamine transmembrane transporter activity (GO:0015186)
Namespace: molecular_function
Definition: Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.
Synonyms: asparagine/glutamine permease activity
glycine transmembrane transporter activity (GO:0015187)
Namespace: molecular_function
Definition: Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
Synonyms: glycine betaine/proline porter activity; glycine transporter activity; proline/glycine/betaine:hydrogen/sodium symporter activity
L-isoleucine transmembrane transporter activity (GO:0015188)
Namespace: molecular_function
Definition: Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.
Synonyms: isoleucine/valine:sodium symporter activity; L-isoleucine transporter activity; leucine/isoleucine/valine porter activity; leucine/valine/isoleucine permease activity
L-lysine transmembrane transporter activity (GO:0015189)
Namespace: molecular_function
Definition: Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
Synonyms: histidine/arginine/lysine/ornithine porter activity; L-lysine permease; lysine permease activity
L-leucine transmembrane transporter activity (GO:0015190)
Namespace: molecular_function
Definition: Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.
Synonyms: L-leucine transporter activity; leucine/isoleucine/valine porter activity; leucine/valine/isoleucine permease activity
L-methionine transmembrane transporter activity (GO:0015191)
Namespace: molecular_function
Definition: Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.
Synonyms: L-methionine transporter activity
L-phenylalanine transmembrane transporter activity (GO:0015192)
Namespace: molecular_function
Definition: Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.
Synonyms: L-phenylalanine permease activity; L-phenylalanine transporter activity
L-proline transmembrane transporter activity (GO:0015193)
Namespace: molecular_function
Definition: Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.
Synonyms: glycine betaine/proline porter activity; L-proline permease activity; L-proline transporter activity; proline/glycine/betaine:hydrogen/sodium symporter activity
L-serine transmembrane transporter activity (GO:0015194)
Namespace: molecular_function
Definition: Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.
Synonyms: L-serine permease activity; L-serine transporter activity; serine transporter activity; threonine/serine:sodium symporter activity
L-threonine transmembrane transporter activity (GO:0015195)
Namespace: molecular_function
Definition: Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.
Synonyms: L-threonine permease activity; L-threonine transporter activity; threonine/serine:sodium symporter activity
L-tryptophan transmembrane transporter activity (GO:0015196)
Namespace: molecular_function
Definition: Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.
Synonyms: L-tryptophan permease activity; L-tryptophan transporter activity; valine/tyrosine/tryptophan permease activity
amino-acid betaine transmembrane transporter activity (GO:0015199)
Namespace: molecular_function
Definition: Enables the transfer of betaine from one side of a membrane to the other. Betaine is the N-trimethyl derivative of an amino acid.
Synonyms: betaine transmembrane transporter activity; betaine/GABA:sodium symporter activity; glycine betaine/proline porter activity; proline/glycine/betaine:hydrogen/sodium symporter activity
methylammonium transmembrane transporter activity (GO:0015200)
Namespace: molecular_function
Definition: Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.
polyamine transmembrane transporter activity (GO:0015203)
Namespace: molecular_function
Definition: Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.
Synonyms: amine/amide/polyamine channel activity
urea transmembrane transporter activity (GO:0015204)
Namespace: molecular_function
Definition: Enables the transfer of urea from one side of a membrane to the other. Urea is the water soluble compound H2N-CO-NH2.
Synonyms: urea transporter activity
nucleobase transmembrane transporter activity (GO:0015205)
Namespace: molecular_function
Definition: Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.
adenine transmembrane transporter activity (GO:0015207)
Namespace: molecular_function
Definition: Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.
guanine transmembrane transporter activity (GO:0015208)
Namespace: molecular_function
Definition: Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.
cytosine transmembrane transporter activity (GO:0015209)
Namespace: molecular_function
Definition: Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.
uracil transmembrane transporter activity (GO:0015210)
Namespace: molecular_function
Definition: Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.
Synonyms: uracil/uridine permease activity
purine nucleoside transmembrane transporter activity (GO:0015211)
Namespace: molecular_function
Definition: Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.
cytidine transmembrane transporter activity (GO:0015212)
Namespace: molecular_function
Definition: Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.
uridine transmembrane transporter activity (GO:0015213)
Namespace: molecular_function
Definition: Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
Synonyms: uracil/uridine permease activity
nucleotide transmembrane transporter activity (GO:0015215)
Namespace: molecular_function
Definition: Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.
ADP transmembrane transporter activity (GO:0015217)
Namespace: molecular_function
Definition: Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.
pyrimidine nucleotide transmembrane transporter activity (GO:0015218)
Namespace: molecular_function
Definition: Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
obsolete protein-DNA complex transmembrane transporter activity (GO:0015219)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of protein-DNA complexes from one side of a membrane to the other.
Synonyms: DNA-protein complex transmembrane transporter activity
Comment: This term was obsoleted because there is no experimental evidence that this function exists.
choline transmembrane transporter activity (GO:0015220)
Namespace: molecular_function
Definition: Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
Synonyms: amino acid/choline transmembrane transporter activity; choline permease activity
lipopolysaccharide transmembrane transporter activity (GO:0015221)
Namespace: molecular_function
Definition: Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
Synonyms: LPS transmembrane transporter activity
obsolete vitamin or cofactor transporter activity (GO:0015223)
Namespace: molecular_function
Definition: OBSOLETE. Enables the directed transport of vitamins or cofactors into, out of or within a cell, or between cells.
Synonyms: vitamin or cofactor transporter activity; vitamin/cofactor transporter activity
Comment: This term was made obsolete because it was replaced by more specific terms.
biopterin transmembrane transporter activity (GO:0015224)
Namespace: molecular_function
Definition: Enables the transfer of biopterin from one side of a membrane to the other. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
Synonyms: biopterin transporter activity
biotin transmembrane transporter activity (GO:0015225)
Namespace: molecular_function
Definition: Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
Synonyms: biotin transporter activity; vitamin B7 transporter activity; vitamin H transporter activity
carnitine transmembrane transporter activity (GO:0015226)
Namespace: molecular_function
Definition: Enables the transfer of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
Synonyms: vitamin Bt transporter activity
O-acyl-L-carnitine transmembrane transporter activity (GO:0015227)
Namespace: molecular_function
Definition: Enables the transfer of O-acyl-L-carnitine from one side of a membrane to the other. O-acyl-L-carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.
Synonyms: acylcarnitine transporter activity
coenzyme A transmembrane transporter activity (GO:0015228)
Namespace: molecular_function
Definition: Enables the transfer of coenzyme A from one side of a membrane to the other. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms: coenzyme A transporter activity
L-ascorbic acid transmembrane transporter activity (GO:0015229)
Namespace: molecular_function
Definition: Enables the transfer of L-ascorbate from one side of a membrane to the other. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.
Synonyms: L-ascorbate transporter activity; vitamin C transporter activity
FAD transmembrane transporter activity (GO:0015230)
Namespace: molecular_function
Definition: Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
Synonyms: FAD carrier activity; FAD transporter activity; flavin adenine dinucleotide carrier activity; flavin adenine dinucleotide transmembrane transporter activity; flavin-adenine dinucleotide carrier activity; flavin-adenine dinucleotide transmembrane transporter activity
5-formyltetrahydrofolate transmembrane transporter activity (GO:0015231)
Namespace: molecular_function
Definition: Enables the transfer of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, from one side of a membrane to the other.
Synonyms: 5-formyltetrahydrofolate transporter activity
heme transmembrane transporter activity (GO:0015232)
Namespace: molecular_function
Definition: Enables the transfer of heme from one side of a membrane to the other.
Synonyms: haem transporter activity; heme transporter activity
pantothenate transmembrane transporter activity (GO:0015233)
Namespace: molecular_function
Definition: Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
Synonyms: pantothenate transporter activity; vitamin B5 transmembrane transporter activity
thiamine transmembrane transporter activity (GO:0015234)
Namespace: molecular_function
Definition: Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
Synonyms: thiamin permease activity; thiamin transmembrane transporter activity; thiamin uptake transporter activity; thiamine permease activity; thiamine uptake transmembrane transporter activity; vitamin B1 transporter activity
obsolete amiloride transmembrane transporter activity (GO:0015240)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of amiloride from one side of a membrane to the other. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.
Synonyms: amiloride transporter activity
Comment: The reason for obsoletion is that these terms are beyond the scope of GO.
fluconazole transmembrane transporter activity (GO:0015244)
Namespace: molecular_function
Definition: Enables the transfer of fluconazole from one side of a membrane to the other. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
Synonyms: fluconazole transporter activity
fatty acid transmembrane transporter activity (GO:0015245)
Namespace: molecular_function
Definition: Enables the transfer of fatty acids from one side of a membrane to the other. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
Synonyms: fatty acid transporter activity; fatty acyl transporter activity; fatty-acyl group transporter activity; peroxisomal fatty acyl transporter
aminophospholipid flippase activity (GO:0015247)
Namespace: molecular_function
Definition: Enables the transfer of aminophospholipids from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.
Synonyms: aminophospholipid transmembrane transporter activity; aminophospholipid transporter activity
obsolete sterol transporter activity (GO:0015248)
Namespace: molecular_function
Definition: OBSOLETE. Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Comment: This term was obsoleted because it is an unnecessary grouping term.
water channel activity (GO:0015250)
Namespace: molecular_function
Definition: Enables the energy-independent facilitated diffusion of water through a transmembrane aqueous pore or channel.
Synonyms: aquaporin