LiteFold/GO huggingface dataset:
diacylglycerol diphosphate phosphatase activity (GO:0000810)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.
Synonyms: DGPP phosphatase activity; DGPP phosphohydrolase activity; diacylglycerol pyrophosphate phosphatase activity
GINS complex (GO:0000811)
Namespace: cellular_component
Definition: A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.
Synonyms: Go, Ichi, Ni and San complex
Swr1 complex (GO:0000812)
Namespace: cellular_component
Definition: A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
Synonyms: SWR-C
ESCRT I complex (GO:0000813)
Namespace: cellular_component
Definition: An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
Synonyms: endosomal sorting complex required for transport
ESCRT II complex (GO:0000814)
Namespace: cellular_component
Definition: An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
Synonyms: endosomal sorting complex required for transport
ESCRT III complex (GO:0000815)
Namespace: cellular_component
Definition: A complex with membrane scission activity that plays a major role in many processes where membranes are remodelled - including endosomal transport (vesicle budding), nuclear envelope organisation (membrane closure, mitotic bridge cleavage), and cytokinesis (abscission).
Synonyms: endosomal sorting complex required for transport
COMA complex (GO:0000817)
Namespace: cellular_component
Definition: A kinetochore multiprotein complex that bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly. In yeast, consists of Ctf19p, Okp1p, Mcm21p, and Ame1p.
Synonyms: Ctf19p-Okp1p-Mcm1p-Ame1p complex
sister chromatid segregation (GO:0000819)
Namespace: biological_process
Definition: The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.
obsolete regulation of glutamine family amino acid metabolic process (GO:0000820)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
Synonyms: regulation of glutamine family amino acid metabolism
Comment: The reason for obsoletion is that this is an unnecessary grouping term.
obsolete regulation of arginine metabolic process (GO:0000821)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
Synonyms: regulation of arginine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
inositol hexakisphosphate binding (GO:0000822)
Namespace: molecular_function
Definition: Binding to inositol hexakisphosphate.
Synonyms: InsP6 binding; IP6 binding
inositol-1,4,5-trisphosphate 6-kinase activity (GO:0000823)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H+.
Synonyms: inositol polyphosphate multikinase activity; inositol trisphosphate 6-kinase activity; IpmK
inositol-1,4,5,6-tetrakisphosphate 3-kinase activity (GO:0000824)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.
Synonyms: 1D-myo-inositol-tetrakisphosphate 3-kinase activity; inositol 1,4,5,6-tetrakisphosphate 3-kinase activity; inositol polyphosphate multikinase activity; inositol tetrakisphosphate 3-kinase activity; IpmK
inositol-1,3,4,5-tetrakisphosphate 6-kinase activity (GO:0000825)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H+.
Synonyms: 1D-myo-inositol-tetrakisphosphate 6-kinase activity; inositol 1,3,4,5-tetrakisphosphate 6-kinase activity; inositol tetrakisphosphate 6-kinase activity
obsolete inositol pyrophosphate synthase activity (GO:0000826)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the phosphorylation of inositol phosphates which possess diphosphate bonds.
Synonyms: inositol diphosphate synthase activity; inositol pyrophosphate synthase activity
Comment: This term was made obsolete because it is incorrectly defined; 'inositol pyrophosphate' is a inositol derivative to which one (or more) pyrophosphate moieties are attached. 'Inositol pyrophosphate synthase' refers to a class of enzymes that catalyze various different reactions that result in the formation of an IP, so one cannot formulate a general reaction for them.
inositol-1,3,4,5,6-pentakisphosphate kinase activity (GO:0000827)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
inositol hexakisphosphate kinase activity (GO:0000828)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
Synonyms: IP6 kinase
diphosphoinositol pentakisphosphate kinase activity (GO:0000829)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
Synonyms: inositol heptakisphosphate kinase activity; PP-IP5 kinase activity
inositol hexakisphosphate 6-kinase activity (GO:0000831)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.
inositol hexakisphosphate 5-kinase activity (GO:0000832)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP.
Synonyms: ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase activity
5-diphosphoinositol pentakisphosphate 4-kinase activity (GO:0000833)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = ADP + 4,5-bis(diphospho)-1D-myo-inositol (1,2,3,6)tetrakisphosphate.
Synonyms: diphosphoinositol-pentakisphosphate 4-kinase activity; inositol heptakisphosphate 4-kinase activity; IP7 4-kinase activity
ER ubiquitin ligase complex (GO:0000835)
Namespace: cellular_component
Definition: A ubiquitin ligase complex found in the ER.
Hrd1p ubiquitin ligase complex (GO:0000836)
Namespace: cellular_component
Definition: A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
Synonyms: HRD1 ubiquitin ligase complex
Doa10p ubiquitin ligase complex (GO:0000837)
Namespace: cellular_component
Definition: A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
Synonyms: Ssm4p ubiquitin ligase complex
Hrd1p ubiquitin ligase ERAD-M complex (GO:0000838)
Namespace: cellular_component
Definition: A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
Hrd1p ubiquitin ligase ERAD-L complex (GO:0000839)
Namespace: cellular_component
Definition: A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
translation repressor activity, non-nucleic acid binding (GO:0000901)
Namespace: molecular_function
Definition: Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.
cell morphogenesis (GO:0000902)
Namespace: biological_process
Definition: The developmental process in which the size or shape of a cell is generated and organized.
Synonyms: cellular morphogenesis
obsolete regulation of cell shape during vegetative growth phase (GO:0000903)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.
Synonyms: cell morphogenesis during vegetative growth phase; cellular morphogenesis during vegetative growth; regulation of cell morphogenesis during vegetative growth phase
Comment: The reason for obsoletion is that biological phases should be captured as extensions.
obsolete cell morphogenesis involved in differentiation (GO:0000904)
Namespace: biological_process
Definition: OBSOLETE. The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
Comment: This term is equivalent to cell morphogenesis.
sporocarp development involved in asexual reproduction (GO:0000905)
Namespace: biological_process
Definition: The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.
Synonyms: conidium development; fruiting body formation involved in asexual reproduction; haploid fruiting; homokaryotic fruiting; imperfect stage fruiting body development; monokaryotic fruiting
6,7-dimethyl-8-ribityllumazine synthase activity (GO:0000906)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.
Synonyms: lumazine synthase activity
sulfonate dioxygenase activity (GO:0000907)
Namespace: molecular_function
Definition: Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.
Synonyms: sulfonate/alpha-ketoglutarate dioxygenase activity; sulphonate dioxygenase activity
taurine dioxygenase activity (GO:0000908)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.
Synonyms: 2-aminoethanesulfonate dioxygenase activity; alpha-ketoglutarate-dependent taurine dioxygenase activity; taurine, 2-oxoglutarate:O2 oxidoreductase (sulfite-forming)
sporocarp development involved in sexual reproduction (GO:0000909)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
Synonyms: ascus development; fruiting body development involved in sexual reproduction; fruiting body formation involved in sexual reproduction; perfect stage fruiting body development
assembly of actomyosin apparatus involved in cytokinesis (GO:0000912)
Namespace: biological_process
Definition: The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
Synonyms: actomyosin apparatus assembly involved in cytokinesis; cytokinesis, formation of actomyosin apparatus; formation of actomyosin apparatus involved in cytokinesis
preprophase band assembly (GO:0000913)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.
Synonyms: preprophase band formation
phragmoplast assembly (GO:0000914)
Namespace: biological_process
Definition: The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).
Synonyms: phragmoplast formation
actomyosin contractile ring assembly (GO:0000915)
Namespace: biological_process
Definition: The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
Synonyms: constriction ring assembly; contractile ring assembly; cytokinesis, actomyosin contractile ring assembly; cytokinesis, actomyosin contractile ring formation; cytokinesis, actomyosin ring biosynthesis; cytokinesis, actomyosin ring formation; cytokinesis, contractile ring assembly; myosin filament organisation involved in cytokinetic actomyosin contractile ring assembly; myosin filament organization involved in cytokinetic actomyosin contractile ring assembly; myosin filament organization of constriction ring assembly; myosin filament organization of contractile ring assembly
actomyosin contractile ring contraction (GO:0000916)
Namespace: biological_process
Definition: The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
Synonyms: actomyosin contractile ring constriction; contractile ring contraction involved in cell cycle cytokinesis; cytokinesis, actomyosin ring contraction; cytokinesis, contractile ring contraction
division septum assembly (GO:0000917)
Namespace: biological_process
Definition: The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
Synonyms: division septum assembly involved in cell cycle cytokinesis; division septum assembly involved in cell cycle cytokinesis involved in mitotic cell cycle; division septum formation; division septum formation involved in cell cycle cytokinesis; division septum formation involved in cell cycle cytokinesis involved in mitotic cell cycle; division septum formation involved in mitotic cell cycle; formation of division septum; formation of division septum involved in mitotic cell cycle; mitotic division septum assembly; septation; septin assembly and septum biosynthesis; septin assembly and septum biosynthesis involved in mitotic cell cycle; septin assembly and septum formation; septin assembly and septum formation involved in mitotic cell cycle
division septum site selection (GO:0000918)
Namespace: biological_process
Definition: The process of marking the site where a division septum will form.
Synonyms: selection of site for barrier cell septum biosynthesis; selection of site for barrier cell septum formation; selection of site for division septum formation; septin assembly and septum biosynthesis; septin assembly and septum formation; septum positioning
septum digestion after cytokinesis (GO:0000920)
Namespace: biological_process
Definition: The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
Synonyms: cell separation after cytokinesis; cell separation following cytokinesis; cytokinetic cell separation; daughter cell separation; mitotic cytokinetic cell separation
Comment: This term should not be used to describe the last step of cytokinesis in organisms without a cell wall, ie, the cell resealing of the plasma membrane via abscission. Consider annotating to 'GO:0061952 midbody abscission' to capture this process.
septin ring assembly (GO:0000921)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
Synonyms: septin assembly and septum biosynthesis; septin assembly and septum formation
spindle pole (GO:0000922)
Namespace: cellular_component
Definition: Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
gamma-tubulin complex (GO:0000930)
Namespace: cellular_component
Definition: A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.
gamma-tubulin ring complex (GO:0000931)
Namespace: cellular_component
Definition: A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.
Synonyms: gamma-tubulin large complex; gamma-tubulin large complex, centrosomal; gamma-tubulin large complex, eMTOC; gamma-tubulin large complex, equatorial microtubule organizing center; gamma-tubulin large complex, equatorial microtubule organizing centre; gamma-tubulin large complex, iMTOC; gamma-tubulin large complex, interphase microtubule organizing center; gamma-tubulin large complex, interphase microtubule organizing centre; gamma-tubulin large complex, mitotic spindle pole body; gamma-tubulin large complex, spindle pole body; gamma-tubulin ring complex, centrosomal; gamma-TuRC
P-body (GO:0000932)
Namespace: cellular_component
Definition: A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
Synonyms: cytoplasmic foci; cytoplasmic mRNA processing body; P body
adventitious septum (GO:0000933)
Namespace: cellular_component
Definition: A cell septum whose formation is independent of nuclear division.
porous cell septum (GO:0000934)
Namespace: cellular_component
Definition: A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.
Synonyms: porous septum
division septum (GO:0000935)
Namespace: cellular_component
Definition: A cell septum which forms as part of the division site and functions in the compartmentalization of a cell into two daughter cells at division. A division septum spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
Synonyms: cell septum surface; complete septum; septum surface
primary cell septum (GO:0000936)
Namespace: cellular_component
Definition: A cell septum that forms following nuclear division.
Synonyms: primary septum
dolipore septum (GO:0000937)
Namespace: cellular_component
Definition: A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).
outer kinetochore (GO:0000940)
Namespace: cellular_component
Definition: The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
Synonyms: condensed chromosome outer kinetochore; condensed nuclear chromosome outer kinetochore; outer kinetochore of condensed chromosome; outer kinetochore of condensed nuclear chromosome; outer kinetochore plate
retrotransposon nucleocapsid (GO:0000943)
Namespace: cellular_component
Definition: A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.
Synonyms: Virus-like particle; VLP
amino acid catabolic process to carboxylic acid via Ehrlich pathway (GO:0000948)
Namespace: biological_process
Definition: The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
aromatic amino acid family catabolic process to alcohol via Ehrlich pathway (GO:0000949)
Namespace: biological_process
Definition: The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.