LiteFold/GO huggingface dataset:
Ycf2/FtsHi complex (GO:0062091)
Namespace: cellular_component
Definition: A protein complex located in the chloroplast inner membrane and facing the stroma that is associated with the chloroplast inner membrane translocase complex and provides the ATPase motor activity to drive import of proteins into the chloroplast stroma.
Synonyms: TIC complex associated chloroplast protein import motor
Yae1-Lto1 complex (GO:0062092)
Namespace: cellular_component
Definition: A cytosolic complex that functions as an substrate-specific adaptor, linking the cytosolic iron-sulfur protein assembly (CIA) targeting complex to apo-Rli1p, an ABC protein involved in ribosome recycling, facilitating Fe-S cluster insertion and the maturation of the Rli1p.
lysophagy (GO:0062093)
Namespace: biological_process
Definition: The selective autophagy process in which a damaged lysosome is degraded by macroautophagy.
stomach development (GO:0062094)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ.
endoplasmic reticulum-peroxisome tethering (GO:0062095)
Namespace: biological_process
Definition: The attachment of an endoplasmic reticulum membrane to a peroxisome via molecular tethers that physically bridge the two membranes and attach them to each other.
kinetochore disassembly (GO:0062096)
Namespace: biological_process
Definition: The disaggregation of a kinetochore into its constituent components.
chemosynthesis (GO:0062097)
Namespace: biological_process
Definition: The cellular metabolic process in which organic chemical compounds are synthesized from carbon-containing molecules and nutrients using energy obtained from the oxidation of inorganic compounds or methane.
regulation of programmed necrotic cell death (GO:0062098)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of programmed necrotic cell death.
negative regulation of programmed necrotic cell death (GO:0062099)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of programmed necrotic cell death.
positive regulation of programmed necrotic cell death (GO:0062100)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of programmed necrotic cell death.
peptidyl-aspartic acid 3-dioxygenase activity (GO:0062101)
Namespace: molecular_function
Definition: Catalysis of the reaction: protein L-aspartate + 2-oxoglutarate + O2 = protein 3-hydroxy-L-aspartate + succinate + CO2.
Synonyms: aspartate beta-hydroxylase activity; aspartyl/asparaginyl beta-hydroxylase activity; aspartylpeptide beta-dioxygenase activity; peptide-aspartate beta-dioxygenase activity; peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity
female germline stem cell symmetric division (GO:0062102)
Namespace: biological_process
Definition: Division of a female germline stem cell to produce two germline stem cells of the same type as the parent.
pumilio-response element binding (GO:0062104)
Namespace: molecular_function
Definition: Binding to a region of RNA containing a Pumilio-response element element. The consensus sequence for the element is UGUAAAUA.
Synonyms: PRE binding
RNA 2'-O-methyltransferase activity (GO:0062105)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.
regulation of protein localization to non-growing cell tip (GO:0062107)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.
negative regulation of protein localization to non-growing cell tip (GO:0062108)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.
regulation of DNA recombinase disassembly (GO:0062109)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of DNA recombinase disassembly, the disaggregation of a DNA recombinase complex into its constituent components.
negative regulation of DNA recombinase disassembly (GO:0062110)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.
fatty acid primary amide biosynthetic process (GO:0062112)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a fatty acid primary amide.
Synonyms: FAPA biosynthesis; FAPA biosynthetic process; fatty acid amide biosynthesis
early phagosome lumen (GO:0062113)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of an early phagosome.
Synonyms: early phagocytic vesicle lumen
phenyloplast (GO:0062116)
Namespace: cellular_component
Definition: A chloroplast-derived plastid in which the solid form of phenol is stored.
LinE complex (GO:0062119)
Namespace: cellular_component
Definition: A protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.
LinE complex assembly (GO:0062120)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components during meiotic prophase to form a LinE complex, the protein complex that associates with chromatin to form linear elements in fission yeast. In S. pombe, the LinE complex contains four main structural components (Rec10, Rec25, Rec27, and Mug20) and other associated proteins.
linear element maturation (GO:0062121)
Namespace: biological_process
Definition: The meiotic cell cycle chromosome organization process in which LinE complexes closely associate with chromatin during meiotic prophase to form mature linear elements.
Synonyms: LinE chromosome loading; LinE focus formation
histone H3K37 methyltransferase activity (GO:0062122)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 37) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 37). This reaction is the addition of a methyl group to the lysine residue at position 37 of the histone H3 protein.
Synonyms: histone H3K37 methylase activity; histone lysine N-methyltransferase activity (H3-K37 specific); histone methyltransferase activity (H3-K37 specific); histone-H3K37 methyltransferase activity
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
regulation of linear element maturation (GO:0062123)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of linear element maturation.
4-hydroxybutyrate receptor activity (GO:0062124)
Namespace: molecular_function
Definition: Combining with 4-hydroxybutyrte to initiate a change in cell activity.
Synonyms: gamma-hydroxybutyrate receptor activity
regulation of mitochondrial gene expression (GO:0062125)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).
fatty acid primary amide metabolic process (GO:0062126)
Namespace: biological_process
Definition: The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.
Synonyms: primary fatty amide metabolic process
fatty acid primary amide catabolic process (GO:0062127)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of primary fatty amides.
Synonyms: primary fatty amide catabolic process
MutSgamma complex (GO:0062128)
Namespace: cellular_component
Definition: A heterodimer involved in the stabilization of DNA recombination intermediates, the promotion of crossover recombination, and the proper assembly of the synaptonemal complex in meiotic prophase nuclei. In yeast the complex consists of two subunits, Msh4 and Msh5.
Synonyms: Msh4-Msh5 complex
chitin-based extracellular matrix (GO:0062129)
Namespace: cellular_component
Definition: Any constituent part of a chitin-based noncellular, hardened, or membranous extracellular matrix secreted from the apical surface of an epithelial sheet.
Synonyms: chitin-based ECM
3-butenylglucosinolate 2-hydroxylase activity (GO:0062131)
Namespace: molecular_function
Definition: Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.
Synonyms: But-3-enyl Glucosinolate-2-hydroxylase activity
regulation of L-glutamine biosynthetic process (GO:0062132)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of L-glutamine biosynthesis.
negative regulation of L-glutamine biosynthetic process (GO:0062133)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.
positive regulation of L-glutamine biosynthetic process (GO:0062134)
Namespace: biological_process
Definition: Any process that starts, increases the frequency, rate or extent of L-glutamine biosynthesis.
low-density lipoprotein receptor complex (GO:0062136)
Namespace: cellular_component
Definition: A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.
Synonyms: LDL receptor complex; LDLR complex; low-density lipoprotein particle receptor complex
cargo receptor complex (GO:0062137)
Namespace: cellular_component
Definition: Any protein complex that is part of a membrane and which functions as a cargo receptor.
camera-type eye photoreceptor cell development (GO:0062139)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a light-responsive receptor in a camera-type eye over time, from its formation to the mature structure.
hyphae septin collar (GO:0062140)
Namespace: cellular_component
Definition: A septin collar in pathogenic fungi involved in the constriction of hyphae at the plant plasmodesma enabling penetration of an adjacent cell.
Synonyms: septin collar of invasive hyphae
nuclear exosome targeting complex (GO:0062141)
Namespace: cellular_component
Definition: A protein-containing complex that functions with the RNA exosome and contributes to the degradation of abberant transcripts.
Synonyms: NEXT complex
L-beta-ethynylserine biosynthetic process (GO:0062142)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.
L-propargylglycine biosynthetic process (GO:0062143)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-propargylglycine (Pra). L-propargylglycine is an antibiotic produced by Streptomyces bacteria.
L-propargylglycine synthase activity (GO:0062144)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate = chloride + H+ + L-propargylglycine.
L-propargylglycine--L-glutamate ligase activity (GO:0062145)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate.
4-chloro-allylglycine synthase activity (GO:0062146)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4-chloro-L-lysine + AH2 + O2 = A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4+.
L-lysine 4-chlorinase activity (GO:0062147)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.
L-gamma-glutamyl-L-propargylglycine hydroxylase activity (GO:0062148)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate.
obsolete detection of stimulus involved in sensory perception of pain (GO:0062149)
Namespace: biological_process
Definition: OBSOLETE. The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
amorpha-4,11-diene 12-monooxygenase activity (GO:0062150)
Namespace: molecular_function
Definition: Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].
mRNA (cytidine-5-)-methyltransferase activity (GO:0062152)
Namespace: molecular_function
Definition: Catalysis of the reaction: a cytidine in mRNA + S-adenosyl-L-methionine = a 5-methylcytidine in mRNA + H+ + S-adenosyl-L-homocysteine.
Synonyms: mRNA (cytosine-5-)-methyltransferase activity
C5-methylcytidine-containing RNA reader activity (GO:0062153)
Namespace: molecular_function
Definition: A protein adaptor that recognizes and binds an RNA molecule modified by C5-methylcytidine.
Synonyms: C5-methylcytidine-containing RNA binding; C5-methylcytosine-containing RNA binding
N6-methyl-AMP deaminase activity (GO:0062154)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + H2O + N6-methyl-AMP = IMP + methylamine. Can also use N6-methyl-dAMP as a substrate.
Synonyms: MAPDA; N6-mAMP deaminase activity; N6-methyl-AMP/dAMP aminohydrolase
mitochondrial ATP-gated potassium channel activity (GO:0062156)
Namespace: molecular_function
Definition: Enables the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.
Synonyms: mitochondrial potassium channel activity; mitoK-ATP activity
mitochondrial ATP-gated potassium channel complex (GO:0062157)
Namespace: cellular_component
Definition: A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.
chloride:proton antiporter activity (GO:0062158)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: chloride(out) + proton(in) = chloride(in) + proton(out).
contractile vacuole complex (GO:0062159)
Namespace: cellular_component
Definition: A non-membrane-bounded organelle of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally. One of its functions is osmoregulatory.
Synonyms: CVC
spongiome (GO:0062160)
Namespace: cellular_component
Definition: A cellular anatomical entity which is a network of tubules and vessicles and is part of the contractile vacuole complex. It is involved in the discharge of water externally. One of its functions is osmoregulatory.
regulation of pyocyanine biosynthetic process (GO:0062161)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.
Synonyms: regulation of pyocyanin biosynthetic process
positive regulation of pyocyanine biosynthetic process (GO:0062162)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.
Synonyms: positive regulation of pyocyanin biosynthetic process
pseudohyphal septin ring assembly (GO:0062163)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.
regulation of pseudohyphal septin ring assembly (GO:0062164)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of pseudohyphal septin ring assembly.
positive regulation of pseudohyphal septin ring assembly (GO:0062165)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.
negative regulation of pseudohyphal septin ring assembly (GO:0062166)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of pseudohyphal septin ring assembly.
complement component C1q complex (GO:0062167)
Namespace: cellular_component
Definition: A protein-containing complex composed of six subunits of each of the three homologous polypeptide chains C1QA, C1QB, and C1QB. It is a subunit of the complement C1 complex. In addition to complement activation, C1q appears to have roles in homeostasis and cellular development, superoxide (O2-) production by neutrophils, blood coagulation and neurological synapse pruning.
Synonyms: C1q; Complement 1q
negative regulation of plus-end directed microtubule sliding (GO:0062168)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of plus-end directed microtubule sliding.
regulation of plus-end directed microtubule sliding (GO:0062169)
Namespace: biological_process
Definition: Any process that mediates the frequency, rate, or extent of plus-end directed microtubule sliding.
obsolete lutein metabolic process (GO:0062170)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.
Synonyms: lutein metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
lutein biosynthetic process (GO:0062171)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of lutein.
Synonyms: lutein anabolism; lutein biosynthesis; lutein formation
lutein catabolic process (GO:0062172)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lutein.
Synonyms: lutein breakdown; lutein catabolism; lutein degradation
brexanolone metabolic process (GO:0062173)
Namespace: biological_process
Definition: The chemical reactions and pathways by which living organisms transform brexanolone.
Synonyms: allopregnanolone metabolic process; allopregnanolone metabolism; allotetrahydroprogesterone metabolic process; allotetrahydroprogesterone metabolism; brexanolone metabolism
brexanolone biosynthetic process (GO:0062174)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of brexanolone.
Synonyms: allopregnanolone anabolism; allopregnanolone biosynthesis; allopregnanolone biosynthetic process; allopregnanolone synthesis; allotetrahydroprogesterone anabolism; allotetrahydroprogesterone biosynthesis; allotetrahydroprogesterone biosynthetic process; allotetrahydroprogesterone synthesis; brexanolone anabolism; brexanolone biosynthesis; brexanolone synthesis
brexanolone catabolic process (GO:0062175)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of brexanolone.
Synonyms: allopregnanolone breakdown; allopregnanolone catabolic process; allopregnanolone catabolism; allopregnanolone degradation; allotetrahydroprogesterone breakdown; allotetrahydroprogesterone catabolic process; allotetrahydroprogesterone catabolism; allotetrahydroprogesterone degradation; brexanolone breakdown; brexanolone catabolism; brexanolone degradation
R-loop processing (GO:0062176)
Namespace: biological_process
Definition: A DNA metabolic process that results in the disassembly of R-loops. R-loops are three-stranded nucleic acid structures consisitng of an RNA:DNA heteroduplex and a looped-out non-template strand. Aberrant formation and persistence of R-loops block transcription elongation and cause DNA damage. Mechanisms that resolve R-loops are essential for genome stability.
Synonyms: R-loop disassembly
radial spoke assembly (GO:0062177)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the radial spoke, a protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules.
vitamin D 23-hydroxylase activity (GO:0062179)
Namespace: molecular_function
Definition: Catalysis of the hydroxylation of C-23 of any form of vitamin D.
25-hydroxycholecalciferol-23-hydroxylase activity (GO:0062180)
Namespace: molecular_function
Definition: Catalysis of the reaction: calcidiol + 2 H+ + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin].
all-trans retinoic acid 4-hydrolase activity (GO:0062182)
Namespace: molecular_function
Definition: Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
all-trans retinoic acid 18-hydroxylase activity (GO:0062183)
Namespace: molecular_function
Definition: Catalysis of the reaction: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-18-hydroxyretinoate + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
testosterone 16-beta-hydroxylase activity (GO:0062184)
Namespace: molecular_function
Definition: Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
secalciferol 1-monooxygenase activity (GO:0062185)
Namespace: molecular_function
Definition: Catalysis of the reaction:2 H+ + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].
anandamide epoxidase activity (GO:0062186)
Namespace: molecular_function
Definition: Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.
Synonyms: arachidonoylethanolamide epoxidase activity
anandamide 8,9 epoxidase activity (GO:0062187)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
anandamide 11,12 epoxidase activity (GO:0062188)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
anandamide 14,15 epoxidase activity (GO:0062189)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(14,15-epoxy-5Z,8Z,11Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].
L-rhamnose mutarotase activity (GO:0062192)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.
D-ribose pyranase activity (GO:0062193)
Namespace: molecular_function
Definition: Catalysis of the reactions: beta-D-ribopyranose = beta-D-ribofuranose, and beta-allofuranose = beta-allopyranose.