LiteFold/GO huggingface dataset:
ciliary transition fiber (GO:0097539)
Namespace: cellular_component
Definition: A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).
Synonyms: centriolar distal appendage; cilial transition fiber; cilial transition fibre; ciliary transition fibre; cilium transition fiber; cilium transition fibre; distal appendage of basal body; distal appendage of centriole; distal appendage of mother centriole; transition fiber; transition fibre
Comment: In mammals, ciliary transition fibers comprise at least five components (Ccdc41/Cep83, Cep89/Cep123, Sclt1, Fbf1, and Cep164) (PMID:24469809).
axonemal central pair (GO:0097540)
Namespace: cellular_component
Definition: Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.
Synonyms: axonemal microtubule central pair; axoneme central pair; axoneme microtubule central pair; central pair; central-pair microtubules
ciliary tip (GO:0097542)
Namespace: cellular_component
Definition: Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
Synonyms: cilial tip; cilium tip; flagellar tip; flagellum tip
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent.
ciliary inversin compartment (GO:0097543)
Namespace: cellular_component
Definition: Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.
Synonyms: cilial inversin compartment; cilium inversin compartment; flagellar inversin compartment; flagellum inversin compartment; Inv compartment of the cilium; inversin compartment
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent.
ciliary shaft (GO:0097544)
Namespace: cellular_component
Definition: The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.
Synonyms: cilial shaft; cilium shaft; flagellar shaft; flagellum shaft
Comment: Note that 'ciliary shaft' is sparingly used in the literature to denote the projecting part of the cilium; many authors would refer to the axoneme instead. However, the definition of GO:0005930 'axoneme' is rather stringent, and the localization of many ciliary proteins would not fit that definition. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.
axonemal doublet microtubule (GO:0097545)
Namespace: cellular_component
Definition: A cellular anatomical entity that is part of an axoneme consisting of a doublet microtubule.
Synonyms: axonemal outer doublet; axoneme outer doublet; DMT; outer doublet; outer-doublet microtubules
synaptic vesicle protein transport vesicle (GO:0097547)
Namespace: cellular_component
Definition: A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.
Synonyms: STV
Comment: This term should not be confused with GO:0008021 'synaptic vesicle'. STVs and synaptic vesicles differ both functionally and morphologically. Functionally, STVs are transport vesicles that deliver synaptic vesicle proteins to synapses, while synaptic vesicles are responsible for transmitter release at synapses. Morphologically, synaptic vesicles are very homogeneous, while STVs are very heterogeneous in size and shape. STVs might be a precursor for synaptic vesicles.
seed abscission (GO:0097548)
Namespace: biological_process
Definition: The controlled shedding of a seed.
obsolete chromatin organization involved in negative regulation of transcription (GO:0097549)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization.
Synonyms: negative regulation of gene-specific transcription from RNA polymerase II promoter by histone modification; negative regulation of global transcription from Pol II promoter by histone modification; negative regulation of transcription by chromatin organization; negative regulation of transcription from Pol II promoter by histone modification; negative regulation of transcription from RNA polymerase II promoter by histone modification; negative regulation of transcription from RNA polymerase II promoter, global by histone modification
Comment: This term was obsoleted because these it was redundant with other terms: heterochromatin assembly and negative regulation of gene expression, epigenetic.
transcription preinitiation complex (GO:0097550)
Namespace: cellular_component
Definition: A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
Synonyms: DNA-templated transcriptional preinitiation complex; PIC; preinitiation complex; transcriptional pre-initiation complex; transcriptional preinitiation complex
mitochondrial double-strand break repair (GO:0097551)
Namespace: biological_process
Definition: The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
Synonyms: mtDSB repair
Comment: Note that the processes of nuclear double-strand break repair and mitochondrial double-strand break repair are genetically separable.
left anterior flagellum (GO:0097554)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.
Synonyms: left anterior cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right anterior flagellum (GO:0097555)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.
Synonyms: right anterior cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right posteriolateral flagellum (GO:0097557)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.
Synonyms: right posteriolateral cilium; right posterolateral cilium; right posterolateral flagellum
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
left ventral flagellum (GO:0097558)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
Synonyms: left ventral cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right ventral flagellum (GO:0097559)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
Synonyms: right ventral cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
left caudal flagellum (GO:0097560)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
Synonyms: left caudal cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right caudal flagellum (GO:0097561)
Namespace: cellular_component
Definition: A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
Synonyms: right caudal cilium
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent; the primary term name reflects frequency of use. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
left middle basal body pair (GO:0097563)
Namespace: cellular_component
Definition: Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right lateral basal body pair (GO:0097564)
Namespace: cellular_component
Definition: Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right middle basal body pair (GO:0097565)
Namespace: cellular_component
Definition: Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
left tetrad (GO:0097566)
Namespace: cellular_component
Definition: Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
median body (GO:0097568)
Namespace: cellular_component
Definition: A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.
Synonyms: parabasal body
Comment: Note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
lateral shield (GO:0097569)
Namespace: cellular_component
Definition: Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent. Also note that, due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
left nucleus (GO:0097571)
Namespace: cellular_component
Definition: One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
right nucleus (GO:0097572)
Namespace: cellular_component
Definition: One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
obsolete glutathione oxidoreductase activity (GO:0097573)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione.
Comment: This term was obsoleted because it is redundant with other terms.
lateral part of cell (GO:0097574)
Namespace: cellular_component
Definition: The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.
lateral cell cortex (GO:0097575)
Namespace: cellular_component
Definition: The region directly beneath the plasma membrane of the lateral portion of the cell.
vacuole fusion (GO:0097576)
Namespace: biological_process
Definition: Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
obsolete sequestering of iron ion (GO:0097577)
Namespace: biological_process
Definition: OBSOLETE. The process of binding or confining iron ions such that they are separated from other components of a biological system.
Synonyms: iron ion retention; iron ion sequestering; iron ion sequestration; iron ion storage; retention of iron ion; sequestration of iron ion; storage of iron ion
Comment: The reason for obsoletion is that this term represents a molecular function, not a biological process.
obsolete sequestering of copper ion (GO:0097578)
Namespace: biological_process
Definition: OBSOLETE. The process of binding or confining copper ions such that they are separated from other components of a biological system.
Synonyms: copper ion retention; copper ion sequestering; copper ion sequestration; copper ion storage; retention of copper ion; sequestration of copper ion; storage of copper ion
Comment: The reason for obsoletion is that this term represents a molecular function, not a biological process
obsolete extracellular sequestering of copper ion (GO:0097579)
Namespace: biological_process
Definition: OBSOLETE. The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.
Synonyms: extracellular copper ion retention; extracellular copper ion sequestering; extracellular copper ion sequestration; extracellular copper ion storage; extracellular retention of copper ion; extracellular sequestration of copper ion; extracellular storage of copper ion
Comment: The reason for obsoletion is that this term represents a molecular function, not a biological process.
obsolete intracellular sequestering of copper ion (GO:0097580)
Namespace: biological_process
Definition: OBSOLETE. The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.
Synonyms: intracellular copper ion retention; intracellular copper ion sequestering; intracellular copper ion sequestration; intracellular copper ion storage; intracellular retention of copper ion; intracellular sequestration of copper ion; intracellular storage of copper ion
Comment: The reason for obsoletion is that this term represents a molecular function, not a biological process.
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex (GO:0097582)
Namespace: cellular_component
Definition: A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.
Synonyms: Pmt1p-Pmt2p complex
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex (GO:0097583)
Namespace: cellular_component
Definition: A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.
Synonyms: Pmt1p-Pmt3p complex
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex (GO:0097584)
Namespace: cellular_component
Definition: A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.
Synonyms: Pmt5p-Pmt2p complex
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex (GO:0097585)
Namespace: cellular_component
Definition: A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.
Synonyms: Pmt5p-Pmt3p complex
dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex (GO:0097586)
Namespace: cellular_component
Definition: A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.
Synonyms: dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p dimer; dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p-Pmt4p dimer complex; Pmt4p-Pmt4p complex
MutLgamma complex (GO:0097587)
Namespace: cellular_component
Definition: A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.
archaeal or bacterial-type flagellum-dependent cell motility (GO:0097588)
Namespace: biological_process
Definition: Cell motility due to movement of bacterial- or archaeal-type flagella.
Comment: Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. This term was added for mapping to the UniProt keyword "flagellar rotation". For manual annotation, please use one of the child terms of GO:0097588 that refer specifically to either archaeal- or bacterial-type flagella.
archaeal-type flagellum (GO:0097589)
Namespace: cellular_component
Definition: A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function.
Synonyms: archaeal flagellum; archaella; archaellum
archaeal-type flagellum-dependent cell motility (GO:0097590)
Namespace: biological_process
Definition: Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.
Synonyms: archaeal-type flagellar cell motility
ventral disc lateral crest (GO:0097591)
Namespace: cellular_component
Definition: Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.
Synonyms: lateral crest; ventral disk lateral crest
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
ventral disc overlap zone (GO:0097592)
Namespace: cellular_component
Definition: A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).
Synonyms: overlap zone; ventral disk overlap zone
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.
ventral disc microtubule array (GO:0097593)
Namespace: cellular_component
Definition: A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.
Synonyms: spiral microtubule array; ventral disc spiral microtubule array; ventral disk microtubule array
Comment: Due to the asymmetric nature of the Giardia trophozoite, this term is defined spatially as the trophozoite is viewed from the dorsal side, with the two nuclei dorsal to the ventral disc, and the ventral disc toward the anterior.