LiteFold/GO huggingface dataset:
uracil import across plasma membrane (GO:0098721)
Namespace: biological_process
Definition: The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
Synonyms: uracil import into cell
asymmetric stem cell division (GO:0098722)
Namespace: biological_process
Definition: Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.
skeletal muscle myofibril (GO:0098723)
Namespace: cellular_component
Definition: A myofibril of a skeletal muscle fiber.
symmetric stem cell division (GO:0098724)
Namespace: biological_process
Definition: Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.
Comment: Examples include the self-renewal of spermatogonial stem cells and (some) division during amplification of skeletal muscle satellite cell populations.
symmetric cell division (GO:0098725)
Namespace: biological_process
Definition: Cell division in which both daughter cells are of the same type.
maintenance of cell number (GO:0098727)
Namespace: biological_process
Definition: Any process by which the numbers of cells of a particular type or in a tissue are maintained.
germline stem cell asymmetric division (GO:0098728)
Namespace: biological_process
Definition: The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.
germline stem cell symmetric division (GO:0098729)
Namespace: biological_process
Definition: Division of a germline stem cell to produce two germline stem cells of the same type as the parent.
male germline stem cell symmetric division (GO:0098730)
Namespace: biological_process
Definition: The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.
obsolete skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration (GO:0098731)
Namespace: biological_process
Definition: OBSOLETE. Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
hemidesmosome associated protein complex (GO:0098733)
Namespace: cellular_component
Definition: Any protein complex that is part of or has some part in a hemidesmosome.
macromolecule depalmitoylation (GO:0098734)
Namespace: biological_process
Definition: The removal of palymitoyl groups from a macromolecule.
positive regulation of the force of heart contraction (GO:0098735)
Namespace: biological_process
Definition: Any process that increases the force of heart muscle contraction.
negative regulation of the force of heart contraction (GO:0098736)
Namespace: biological_process
Definition: Any process that decreases the force of heart muscle contraction.
protein insertion into plasma membrane (GO:0098737)
Namespace: biological_process
Definition: The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
import across plasma membrane (GO:0098739)
Namespace: biological_process
Definition: The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.
Synonyms: uptake
obsolete multi organism cell adhesion (GO:0098740)
Namespace: biological_process
Definition: OBSOLETE. Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms.
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)
Namespace: biological_process
Definition: OBSOLETE. The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
Comment: The reason for obsoletion is that this term represents a method of annotation rather than a distinct biological process.
cell aggregation (GO:0098743)
Namespace: biological_process
Definition: The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
1-phosphatidylinositol 4-kinase activator activity (GO:0098744)
Namespace: molecular_function
Definition: Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.
RNA decapping complex (GO:0098745)
Namespace: cellular_component
Definition: A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.
Synonyms: Dcp1-Dcp2 complex
Comment: Additional components may be present, for example in ascomycetes this complex includes an additional regulatory subunit, Edc1.
fast, calcium ion-dependent exocytosis of neurotransmitter (GO:0098746)
Namespace: biological_process
Definition: The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Synonyms: synchronous, calcium ion-dependent exocytosis of neurotransmitter
slow, calcium ion-dependent exocytosis of neurotransmitter (GO:0098747)
Namespace: biological_process
Definition: The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.
FYXD domain binding (GO:0098750)
Namespace: molecular_function
Definition: Binding to a FXYD domain.
bone cell development (GO:0098751)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Comment: Not to be used for manual annotation. Please choose a more specific cell development term or if not possible, bone or bone tissue development.
obsolete anchored component of the cytoplasmic side of the plasma membrane (GO:0098753)
Namespace: cellular_component
Definition: OBSOLETE. The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
detoxification (GO:0098754)
Namespace: biological_process
Definition: Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
maintenance of seed dormancy by absisic acid (GO:0098755)
Namespace: biological_process
Definition: The process by which seed dormancy is maintained by the presence of absisic acid.
response to interleukin-21 (GO:0098756)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
Synonyms: response to IL-21
cellular response to interleukin-21 (GO:0098757)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
Synonyms: cellular response to IL-21
cellular response to interleukin-8 (GO:0098759)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.
Synonyms: cellular response to IL-8
response to interleukin-7 (GO:0098760)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
Synonyms: response to IL-7
cellular response to interleukin-7 (GO:0098761)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
Synonyms: cellular response to IL-7
meiotic cell cycle phase (GO:0098762)
Namespace: biological_process
Definition: One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
Comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
mitotic cell cycle phase (GO:0098763)
Namespace: biological_process
Definition: One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
Comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiosis I cell cycle phase (GO:0098764)
Namespace: biological_process
Definition: A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiosis II cell cycle phase (GO:0098765)
Namespace: biological_process
Definition: A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).
Comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
obsolete meiosis I M phase (GO:0098766)
Namespace: biological_process
Definition: OBSOLETE. M phase during meiosis I.
Comment: Obsoleted because added in error.
obsolete meiosis II M phase (GO:0098767)
Namespace: biological_process
Definition: OBSOLETE. M phase during meiosis II.
Comment: Obsoleted because added in error.
meiotic prometaphase I (GO:0098768)
Namespace: biological_process
Definition: The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.
Comment: This term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation should be to 'regulation of x/y phase transition' or to a process which occurs during the reported phase (e.g. mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
TIMP family protein binding (GO:0098769)
Namespace: molecular_function
Definition: Binding to a member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family.
FBXO family protein binding (GO:0098770)
Namespace: molecular_function
Definition: Binding to a member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.
inorganic ion homeostasis (GO:0098771)
Namespace: biological_process
Definition: Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
molecular function regulator activity (GO:0098772)
Namespace: molecular_function
Definition: A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition.
Synonyms: molecular function regulator
Comment: This term should only be used in cases when the regulator directly interacts with the enzyme, but does not result in a covalent modification.
skin epidermis development (GO:0098773)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.
curli (GO:0098774)
Namespace: cellular_component
Definition: A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.
Synonyms: tafi; thin aggregative fimbrae
curli assembly (GO:0098775)
Namespace: biological_process
Definition: The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.
protein transport across the cell outer membrane (GO:0098776)
Namespace: biological_process
Definition: The directed movement of proteins across the cell outer membrane.
protein secretion by the type VIII secretion system (GO:0098777)
Namespace: biological_process
Definition: Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.
Synonyms: T8SS
Comment: This term is defined so as to leave open the possibility that things other than curli subunits are secreted via same secretory system as that used by curli subunits.
curli subunit secretion coupled to curli assembly (GO:0098778)
Namespace: biological_process
Definition: The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.
Synonyms: extracellular nucleation-precipitation pathway
obsolete positive regulation of mitophagy in response to mitochondrial depolarization (GO:0098779)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
Comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using another term.
response to mitochondrial depolarisation (GO:0098780)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.
obsolete ncRNA transcription (GO:0098781)
Namespace: biological_process
Definition: OBSOLETE. The transcription of non (protein) coding RNA from a DNA template.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
mechanosensitive potassium channel activity (GO:0098782)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.
Synonyms: mechanically-gated potassium channel activity
biofilm matrix organization (GO:0098784)
Namespace: biological_process
Definition: A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.
Synonyms: biofilm matrix organization and biogenesis
biofilm matrix disassembly (GO:0098786)
Namespace: biological_process
Definition: A process that results in the disassembly of a biofilm matrix.
obsolete mRNA cleavage involved in mRNA processing (GO:0098787)
Namespace: biological_process
Definition: OBSOLETE. Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.
Comment: This term was obsoleted because it represents a molecular function
dendritic knob (GO:0098788)
Namespace: cellular_component
Definition: The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.
Synonyms: apical dendritic knob
obsolete pre-mRNA cleavage required for polyadenylation (GO:0098789)
Namespace: biological_process
Definition: OBSOLETE. The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
Synonyms: cleavage and polyadenylylation specificity factor activity; pre-mRNA cleavage factor activity
obsolete ncRNA transcription associated with protein coding gene TSS/TES (GO:0098790)
Namespace: biological_process
Definition: OBSOLETE. The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes.
Synonyms: pasRNA transcription
Comment: The reason for obsoletion is that this term was added in error.
Golgi apparatus subcompartment (GO:0098791)
Namespace: cellular_component
Definition: A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi apparatus.
Synonyms: Golgi subcompartment
xenophagy (GO:0098792)
Namespace: biological_process
Definition: The selective degradation of intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) by macroautophagy.
postsynapse (GO:0098794)
Namespace: cellular_component
Definition: The part of a synapse that is part of the post-synaptic cell.
global gene silencing by mRNA cleavage (GO:0098795)
Namespace: biological_process
Definition: A posttranscriptional gene silencing pathway that involves the cleavage of mRNAs in a non-gene-specific manner.
Synonyms: gene silencing by mRNA cleavage; mRNA cleavage involved in gene silencing; mRNA destabilization-mediated gene silencing; RNA interference, targeting of mRNA for destruction; targeting of mRNA for destruction involved in RNA interference
membrane protein complex (GO:0098796)
Namespace: cellular_component
Definition: Any protein complex that is part of a membrane.
plasma membrane protein complex (GO:0098797)
Namespace: cellular_component
Definition: Any protein complex that is part of the plasma membrane.
mitochondrial protein-containing complex (GO:0098798)
Namespace: cellular_component
Definition: A protein complex that is part of a mitochondrion.
Synonyms: mitochondrial protein complex
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
inner mitochondrial membrane protein complex (GO:0098800)
Namespace: cellular_component
Definition: Any protein complex that is part of the inner mitochondrial membrane.
regulation of renal system process (GO:0098801)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.
plasma membrane signaling receptor complex (GO:0098802)
Namespace: cellular_component
Definition: Any protein complex that is part of the plasma membrane and which functions as a signaling receptor.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
respiratory chain complex (GO:0098803)
Namespace: cellular_component
Definition: Any protein complex that is part of a respiratory chain.
Synonyms: respirasome
non-motile cilium membrane (GO:0098804)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding a non-motile cilium.
Synonyms: nonmotile primary cilium membrane
obsolete miRNA-mediated gene silencing by mRNA deadenylation (GO:0098806)
Namespace: biological_process
Definition: OBSOLETE. An RNA interference pathway in which a miRNA binding to mRNA triggers shortening of the poly(A) tail of a nuclear-transcribed mRNA, resulting in destabilization of the mRNA and a reduction the amount of translated transcript.
Synonyms: deadenylation involved in gene silencing by miRNA; mRNA deadenylation-mediated gene silencing by miRNA
Comment: This term was obsoleted because it represents the same process as miRNA-mediated gene silencing by mRNA destabilization ; GO:0035279.
chloroplast thylakoid membrane protein complex (GO:0098807)
Namespace: cellular_component
Definition: A protein complex that is part of a chloroplast thylakoid membrane.
mRNA cap binding (GO:0098808)
Namespace: molecular_function
Definition: Binding to a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.