LiteFold/GO huggingface dataset:
obsolete positive regulation of invadopodium assembly (GO:1905926)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium assembly.
Synonyms: activation of invadopodium assembly; activation of invadopodium formation; positive regulation of invadopodium formation; up regulation of invadopodium assembly; up regulation of invadopodium formation; up-regulation of invadopodium assembly; up-regulation of invadopodium formation; upregulation of invadopodium assembly; upregulation of invadopodium formation
Comment: This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.
obsolete regulation of invadopodium disassembly (GO:1905927)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of invadopodium disassembly.
Comment: This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.
obsolete negative regulation of invadopodium disassembly (GO:1905928)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of invadopodium disassembly.
Synonyms: down regulation of invadopodium disassembly; down-regulation of invadopodium disassembly; downregulation of invadopodium disassembly; inhibition of invadopodium disassembly
Comment: This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.
obsolete obsolete regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905930)
Namespace: biological_process
Definition: OBSOLETE. OBSOLETE. Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
Synonyms: regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; regulation of VSMC differentiation involved in phenotypic dimorphism; regulation of VSMC differentiation involved in phenotypic switching
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905931)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
Synonyms: down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; down regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; down regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; down regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; down regulation of VSMC differentiation involved in phenotypic dimorphism; down regulation of VSMC differentiation involved in phenotypic switching; down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; down-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; down-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; down-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; down-regulation of VSMC differentiation involved in phenotypic dimorphism; down-regulation of VSMC differentiation involved in phenotypic switching; downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; downregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; downregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; downregulation of vascular smooth muscle cell differentiation involved in phenotypic switching; downregulation of VSMC differentiation involved in phenotypic dimorphism; downregulation of VSMC differentiation involved in phenotypic switching; inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; inhibition of vascular associated smooth muscle cell differentiation involved in phenotypic switching; inhibition of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; inhibition of vascular smooth muscle cell differentiation involved in phenotypic switching; inhibition of VSMC differentiation involved in phenotypic dimorphism; inhibition of VSMC differentiation involved in phenotypic switching; negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; negative regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; negative regulation of VSMC differentiation involved in phenotypic dimorphism; negative regulation of VSMC differentiation involved in phenotypic switching
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905932)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation involved in phenotypic switching.
Synonyms: activation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; activation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; activation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; activation of vascular smooth muscle cell differentiation involved in phenotypic switching; activation of VSMC differentiation involved in phenotypic dimorphism; activation of VSMC differentiation involved in phenotypic switching; positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; positive regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; positive regulation of VSMC differentiation involved in phenotypic dimorphism; positive regulation of VSMC differentiation involved in phenotypic switching; up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; up regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; up regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; up regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; up regulation of VSMC differentiation involved in phenotypic dimorphism; up regulation of VSMC differentiation involved in phenotypic switching; up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; up-regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; up-regulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; up-regulation of vascular smooth muscle cell differentiation involved in phenotypic switching; up-regulation of VSMC differentiation involved in phenotypic dimorphism; up-regulation of VSMC differentiation involved in phenotypic switching; upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic dimorphism; upregulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching; upregulation of vascular smooth muscle cell differentiation involved in phenotypic dimorphism; upregulation of vascular smooth muscle cell differentiation involved in phenotypic switching; upregulation of VSMC differentiation involved in phenotypic dimorphism; upregulation of VSMC differentiation involved in phenotypic switching
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of cell fate determination (GO:1905933)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cell fate determination.
negative regulation of cell fate determination (GO:1905934)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of cell fate determination.
Synonyms: down regulation of cell fate determination; down-regulation of cell fate determination; downregulation of cell fate determination; inhibition of cell fate determination
positive regulation of cell fate determination (GO:1905935)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cell fate determination.
Synonyms: activation of cell fate determination; up regulation of cell fate determination; up-regulation of cell fate determination; upregulation of cell fate determination
regulation of germ cell proliferation (GO:1905936)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of germ cell proliferation.
negative regulation of germ cell proliferation (GO:1905937)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.
Synonyms: down regulation of germ cell proliferation; down-regulation of germ cell proliferation; downregulation of germ cell proliferation; inhibition of germ cell proliferation
positive regulation of germ cell proliferation (GO:1905938)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of germ cell proliferation.
Synonyms: activation of germ cell proliferation; up regulation of germ cell proliferation; up-regulation of germ cell proliferation; upregulation of germ cell proliferation
regulation of gonad development (GO:1905939)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of gonad development.
Synonyms: regulation of gonadogenesis
negative regulation of gonad development (GO:1905940)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.
Synonyms: down regulation of gonad development; down regulation of gonadogenesis; down-regulation of gonad development; down-regulation of gonadogenesis; downregulation of gonad development; downregulation of gonadogenesis; inhibition of gonad development; inhibition of gonadogenesis; negative regulation of gonadogenesis
positive regulation of gonad development (GO:1905941)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of gonad development.
Synonyms: activation of gonad development; activation of gonadogenesis; positive regulation of gonadogenesis; up regulation of gonad development; up regulation of gonadogenesis; up-regulation of gonad development; up-regulation of gonadogenesis; upregulation of gonad development; upregulation of gonadogenesis
negative regulation of formation of growth cone in injured axon (GO:1905943)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of formation of growth cone in injured axon.
Synonyms: down regulation of formation of growth cone in injured axon; down-regulation of formation of growth cone in injured axon; downregulation of formation of growth cone in injured axon; inhibition of formation of growth cone in injured axon
positive regulation of formation of growth cone in injured axon (GO:1905944)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of formation of growth cone in injured axon.
Synonyms: activation of formation of growth cone in injured axon; up regulation of formation of growth cone in injured axon; up-regulation of formation of growth cone in injured axon; upregulation of formation of growth cone in injured axon
negative regulation of response to calcium ion (GO:1905946)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion.
Synonyms: down regulation of response to Ca2+ ion; down regulation of response to calcium ion; down-regulation of response to Ca2+ ion; down-regulation of response to calcium ion; downregulation of response to Ca2+ ion; downregulation of response to calcium ion; inhibition of response to Ca2+ ion; inhibition of response to calcium ion; negative regulation of response to Ca2+ ion
positive regulation of response to calcium ion (GO:1905947)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of response to calcium ion.
Synonyms: activation of response to Ca2+ ion; activation of response to calcium ion; positive regulation of response to Ca2+ ion; up regulation of response to Ca2+ ion; up regulation of response to calcium ion; up-regulation of response to Ca2+ ion; up-regulation of response to calcium ion; upregulation of response to Ca2+ ion; upregulation of response to calcium ion
ABC-type 3',5'-cyclic GMP transmembrane transporter activity (GO:1905948)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + 3',5'-cyclic GMP(in) = ADP + phosphate + 3',5'-cyclic GMP(out).
Synonyms: 3',5'-cyclic GMP transmembrane-transporting ATPase activity; ATP-dependent 3',5'-cyclic GMP transmembrane transporter activity; ATPase-coupled 3',5'-cyclic GMP transmembrane transporter activity; ATPase-coupled cGMP transmembrane transporter activity
negative regulation of calcium ion import across plasma membrane (GO:1905949)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import across plasma membrane.
Synonyms: down regulation of calcium ion import across plasma membrane; down-regulation of calcium ion import across plasma membrane; downregulation of calcium ion import across plasma membrane; inhibition of calcium ion import across plasma membrane
Comment: An example of this is PPP3CA in human (Q08209) in PMID:17640527 (inferred from direct assay).
mitochondrion DNA recombination (GO:1905951)
Namespace: biological_process
Definition: Any DNA recombination that takes place in mitochondrion.
Synonyms: DNA recombination in mitochondria
regulation of lipid localization (GO:1905952)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of lipid localization.
Synonyms: regulation of lipid localisation
negative regulation of lipid localization (GO:1905953)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization.
Synonyms: down regulation of lipid localisation; down regulation of lipid localization; down-regulation of lipid localisation; down-regulation of lipid localization; downregulation of lipid localisation; downregulation of lipid localization; inhibition of lipid localisation; inhibition of lipid localization; negative regulation of lipid localisation
positive regulation of lipid localization (GO:1905954)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of lipid localization.
Synonyms: activation of lipid localisation; activation of lipid localization; positive regulation of lipid localisation; up regulation of lipid localisation; up regulation of lipid localization; up-regulation of lipid localisation; up-regulation of lipid localization; upregulation of lipid localisation; upregulation of lipid localization
negative regulation of endothelial tube morphogenesis (GO:1905955)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis.
Synonyms: down regulation of endothelial tube morphogenesis; down-regulation of endothelial tube morphogenesis; downregulation of endothelial tube morphogenesis; inhibition of endothelial tube morphogenesis
positive regulation of endothelial tube morphogenesis (GO:1905956)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis.
Synonyms: activation of endothelial tube morphogenesis; up regulation of endothelial tube morphogenesis; up-regulation of endothelial tube morphogenesis; upregulation of endothelial tube morphogenesis
regulation of cellular response to alcohol (GO:1905957)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cellular response to alcohol.
negative regulation of cellular response to alcohol (GO:1905958)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.
Synonyms: down regulation of cellular response to alcohol; down-regulation of cellular response to alcohol; downregulation of cellular response to alcohol; inhibition of cellular response to alcohol
positive regulation of cellular response to alcohol (GO:1905959)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cellular response to alcohol.
Synonyms: activation of cellular response to alcohol; up regulation of cellular response to alcohol; up-regulation of cellular response to alcohol; upregulation of cellular response to alcohol
response to differentiation-inducing factor 2 (GO:1905960)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.
Synonyms: response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one; response to DIF-2; response to DIF2
protein-cysteine S-palmitoyltransferase complex (GO:1905961)
Namespace: cellular_component
Definition: A protein complex which is capable of protein-cysteine S-palmitoyltransferase activity.
Synonyms: Palmitoyltransferase ERF2-SHR5 complex; Palmitoyltransferase ERF2/SHR5 complex
Comment: An example of this is ERF2 in Saccharomyces cerevisiae (Q06551) in PMID:20851885 (inferred from direct assay)
glutamatergic neuron differentiation (GO:1905962)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.
amyloid fibril formation (GO:1990000)
Namespace: biological_process
Definition: The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins.
Synonyms: amyloid fibril assembly; amyloid structure assembly; amyloid structure formation
Comment: Although deposition of amyloid fibrils is associated with diseases, e.g. Alzheimer's disease, amyloid formation is a normal process. Disease occurs when the balance between amyloid formation and clearance is disrupted (reviewed e.g. in PMID:29654159 and PMID:28937655). An example of a normal amyloid complex is composed of human RIP1 and RIP3 kinases (PMID:22817896).
obsolete inhibition of cysteine-type endopeptidase activity involved in apoptotic process (GO:1990001)
Namespace: biological_process
Definition: OBSOLETE. Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.
Comment: The reason for obsoletion is that this term represents a GO-CAM model.
IDP phosphatase activity (GO:1990003)
Namespace: molecular_function
Definition: Catalysis of the reaction: IDP + H2O = IMP + H+ + phosphate.
Synonyms: IDP diphosphatase activity; IDPase activity; inosine diphosphatase activity; inosine-diphosphatase activity
obsolete XDP phosphatase activity (GO:1990004)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: XDP + H2O = XMP + phosphate.
Comment: This term was obsoleted because there is no evidence that this reaction exist in vivo.
granular vesicle (GO:1990005)
Namespace: cellular_component
Definition: A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
amorphous vesicle (GO:1990006)
Namespace: cellular_component
Definition: A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.
membrane stack (GO:1990007)
Namespace: cellular_component
Definition: A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.
neurosecretory vesicle (GO:1990008)
Namespace: cellular_component
Definition: A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.
retinal cell apoptotic process (GO:1990009)
Namespace: biological_process
Definition: Any apoptotic process in a retinal cell.
Synonyms: induction of retinal programmed cell death
compound eye retinal cell apoptotic process (GO:1990010)
Namespace: biological_process
Definition: Any apoptotic process in a compound eye retinal cell.
laminated body (GO:1990011)
Namespace: cellular_component
Definition: Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.
Synonyms: laminated inclusion body
orthogonal array (GO:1990014)
Namespace: cellular_component
Definition: Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).
Synonyms: OAP; orthogonal array of particles; square array
ensheathing process (GO:1990015)
Namespace: cellular_component
Definition: A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.
Synonyms: ensheathing process of Schwann cell
neck portion of tanycyte (GO:1990016)
Namespace: cellular_component
Definition: Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
Synonyms: neck portion
somatic portion of tanycyte (GO:1990017)
Namespace: cellular_component
Definition: Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
Synonyms: somatic portion