LiteFold/GO huggingface dataset:
acireductone synthase activity (GO:0043874)
Namespace: molecular_function
Definition: Catalysis of the reactions:5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate.
Synonyms: 5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing); E-1; E-1 enolase-phosphatase
Comment: This activity is involved in the process of methionine salvage.
2-ketobutyrate formate-lyase activity (GO:0043875)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.
Synonyms: keto-acid formate acetyltransferase; KFL; TdcE
Comment: This function is part of an anaerobic pathway for the catabolism of L-threonine.
D-threonine aldolase activity (GO:0043876)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.
Synonyms: D-allo-TA; D-allo-threonine aldolase activity; D-TA; DtaAS; low-specificity D-threonine aldolase
galactosamine-6-phosphate isomerase activity (GO:0043877)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH4+.
Synonyms: AgaI; galactosamine-6-phosphate deaminase activity
Comment: This function is part of the pathway of N-acetyl-galactosamine and galactosamine utilization.
crotonyl-CoA reductase activity (GO:0043880)
Namespace: molecular_function
Definition: Catalysis of the reaction: butanoyl-CoA + NADP+ = (2E)-butenoyl-CoA + NADPH + H+. (2E)-butenoyl-CoA is also called crotonyl-CoA.
Synonyms: CCR; crotonyl-coenzyme A reductase activity
mesaconyl-CoA hydratase activity (GO:0043881)
Namespace: molecular_function
Definition: Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.
Synonyms: beta-methylmalyl-CoA dehydratase activity; mch; mesaconyl-coenzyme A hydratase activity
Comment: This function is part of an alternate glyoxylate cycle for acetate assimilation.
CO-methylating acetyl-CoA synthase activity (GO:0043884)
Namespace: molecular_function
Definition: Catalysis of the reaction: Co(I)-[corrinoid Fe-S protein] + acetyl-CoA + H+ = methyl-Co(III)-[corrinoid Fe-S protein] + CO + CoA.
Synonyms: acetyl-CoA synthase activity; acetyl-CoA:corrinoid protein O-acetyltransferase activity; ACS; CO-methylating acetyl-coenzyme A synthase activity
anaerobic carbon-monoxide dehydrogenase activity (GO:0043885)
Namespace: molecular_function
Definition: Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.
Synonyms: carbon monoxide dehydrogenase (ferredoxin) activity; carbon monoxide dehydrogenase activity; carbon-monoxide dehydrogenase (ferredoxin) activity; carbon-monoxide dehydrogenase activity; carbon-monoxide,water:ferredoxin oxidoreductase activity; carbon-monoxide:(acceptor) oxidoreductase activity; CO dehydrogenase activity; CO-dehydrogenase (ferredoxin) activity; CO-dehydrogenase activity; CODH
structural constituent of carboxysome shell (GO:0043886)
Namespace: molecular_function
Definition: The action of a molecule that contributes to the structural integrity of a carboxysome shell, an organelle found in all cyanobacteria and some chemoautotrophs, consisting of a proteinaceous coat and enzymes for the fixation of CO2.
Synonyms: structural constituent of carboxysome
melibiose:sodium symporter activity (GO:0043887)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).
Synonyms: MelB; melibiose carrier protein; melibiose permease; melibiose-Na+ symporter activity; melibiose-sodium symporter activity; melibiose/Na+ symporter activity; melibiose/sodium symporter activity; melibiose:Na+ symporter activity; Na+ (Li+)/melibiose symporter activity; Na+-melibiose symporter activity; Na+/melibiose symporter activity; Na+:melibiose symporter activity; sodium-melibiose symporter activity; sodium/melibiose symporter activity; sodium:melibiose symporter activity; thiomethylgalactoside permease II
obsolete (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity (GO:0043888)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate = 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate.
Synonyms: 2,3-dGGGPS; DGGGP synthase activity; DGGGPS; UbiA
Comment: This function is involved in archaeal lipid synthesis. The reason for obsoletion is that this term is equivalent to GO:0047295 geranylgeranylglycerol-phosphate geranylgeranyltransferase activity.
N-acetylgalactosamine-6-sulfatase activity (GO:0043890)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.
Synonyms: acetylgalactosamine 6-sulfatase activity; chondroitin sulfatase; chondroitinase; chondroitinsulfatase; galactose-6-sulfate sulfatase activity; N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity; N-acetylgalactosamine 6-sulfatase activity; N-acetylgalactosamine-6-sulfate sulfatase activity
methylglyoxal reductase (NADPH) activity (GO:0043892)
Namespace: molecular_function
Definition: Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.
Synonyms: Gre2; lactaldehyde dehydrogenase (NADP+); lactaldehyde:NADP+ oxidoreductase activity; methylglyoxal reductase (NADPH-dependent) activity
acetate:monoatomic cation symporter activity (GO:0043893)
Namespace: molecular_function
Definition: Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).
Synonyms: acetate permease; acetate-cation symporter activity; acetate/cation symporter activity; acetate:cation symporter activity; ActP; cation-acetate symporter activity; cation/acetate symporter activity; cation:acetate symporter activity
acetyl-CoA synthetase acetyltransferase activity (GO:0043894)
Namespace: molecular_function
Definition: Catalysis of the acetylation of a lysine of the enzyme acetyl-CoA ligase, using acetyl-CoA as substrate. In Bacillus subtilis, this is Lys609, but it may correspond to another position in orthologs. This acetylation results in inhibition of acetyl-CoA synthetase.
Synonyms: acetate CoA ligase acetyltransferase activity; acetate-CoA ligase acetyltransferase activity; acetyl CoA synthetase acetyltransferase activity; Pat enzyme; protein acetyltransferase activity
cyclomaltodextrin glucanotransferase activity (GO:0043895)
Namespace: molecular_function
Definition: Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.
Synonyms: 1,4-alpha-D-glucan 4-alpha-D-(1,4-alpha-D-glucano)-transferase (cyclizing); alpha-1,4-glucan 4-glycosyltransferase, cyclizing; alpha-cyclodextrin glucanotransferase; alpha-cyclodextrin glycosyltransferase; Bacillus macerans amylase; beta-cyclodextrin glucanotransferase; beta-cyclodextrin glycosyltransferase; BMA; CGTase; cyclodextrin glucanotransferase; cyclodextrin glycosyltransferase; cyclomaltodextrin glucotransferase; cyclomaltodextrin glycosyltransferase; gamma-cyclodextrin glycosyltransferase; konchizaimu; neutral-cyclodextrin glycosyltransferase
glucan 1,6-alpha-glucosidase activity (GO:0043896)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.
Synonyms: exo-1,6-alpha-glucosidase activity; exo-1,6-beta-glucosidase; glucan alpha-1,6-D-glucohydrolase activity; glucan-1,6-alpha-glucosidase activity; glucodextranase activity; glucodextrinase
glucan 1,4-alpha-maltohydrolase activity (GO:0043897)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.
Synonyms: 1,4-alpha-D-glucan alpha-maltohydrolase activity; glucan-1,4-alpha-maltohydrolase activity; maltogenic alpha-amylase activity
2,3-dihydroxybiphenyl 1,2-dioxygenase activity (GO:0043898)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.
Synonyms: 2,3-dihydroxybiphenyl-1,2-dioxygenase activity; BphC
phosphoserine:homoserine phosphotransferase activity (GO:0043899)
Namespace: molecular_function
Definition: Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.
Synonyms: thrH
obsolete regulation of multi-organism process (GO:0043900)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete negative regulation of multi-organism process (GO:0043901)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete positive regulation of multi-organism process (GO:0043902)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
Comment: This term was obsoleted because it is an unnecessary grouping term.
regulation of biological process involved in symbiotic interaction (GO:0043903)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
Synonyms: regulation of interspecies interactions between organisms; regulation of symbiosis, encompassing mutualism through parasitism; regulation of symbiotic process
Comment: regulation of interspecies interactions between organisms
isochorismate pyruvate lyase activity (GO:0043904)
Namespace: molecular_function
Definition: Catalysis of the reaction: isochorismate = salicylate + pyruvate.
Synonyms: IPL; isochorismate-pyruvate lyase activity
L-seryl-tRNA(Thr) hydrolase activity (GO:0043905)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).
Synonyms: Ser-tRNA(Thr) hydrolase activity; Ser-tRNAThr hydrolase activity
Ala-tRNA(Pro) deacylase activity (GO:0043906)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).
Synonyms: Ala-tRNAPro hydrolase activity
Cys-tRNA(Pro) deacylase activity (GO:0043907)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-cysteinyl-tRNA(Pro) + H2O = tRNA(Pro) + L-cysteine + H+.
Synonyms: Cys-tRNA(Pro) deacetylase activity; Cys-tRNAPro hydrolase activity
Ser(Gly)-tRNA(Ala) hydrolase activity (GO:0043908)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).
Synonyms: Ser(Gly)-tRNAAla hydrolase activity
N-acetylcitrulline deacetylase activity (GO:0043909)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.
Synonyms: acetylcitrulline deacetylase activity; N-acetyl-L-citrulline deacetylase activity
ATP:coenzyme F420 adenylyltransferase activity (GO:0043910)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.
Synonyms: ATP:coenzyme F420 adenyltransferase activity; coenzyme F390-A synthetase activity
obsolete D-lysine oxidase activity (GO:0043912)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: D-lysine + H2O + O2 = 6-amino-2-oxohexanoate + H2O2 + NH4+.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete chromosome segregation-directing complex (GO:0043913)
Namespace: cellular_component
Definition: OBSOLETE. A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology.
Synonyms: chromosome segregation directing complex; longitudinal peptidoglycan synthesis-directing complex; MreBCD complex
Comment: This term was obsoleted because the three proteins mentioned in the definition are not part of the same complex.
NAD(P)H sulfur oxidoreductase (CoA-dependent) activity (GO:0043914)
Namespace: molecular_function
Definition: Catalysis of the reaction: hydrogen sulfide + NAD(P)+ = sulfur + NAD(P)H.
Synonyms: CoA-dependent NAD(P)H sulfur oxidoreductase activity; coenzyme A-dependent NAD(P)H sulfur oxidoreductase activity; NAD(P)H elemental sulfur oxidoreductase activity; NAD(P)H sulfur oxidoreductase activity; NAD(P)H sulphur oxidoreductase activity; NAD(P)H:sulfur oxidoreductase activity; NADPH:sulfur oxidoreductase activity; NADPH:sulphur oxidoreductase activity; NSR
L-seryl-tRNA(Sec) kinase activity (GO:0043915)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
Synonyms: O-phosphoseryl-tRNA(Sec) kinase activity
DNA-7-methylguanine glycosylase activity (GO:0043916)
Namespace: molecular_function
Definition: Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.
ribose 1,5-bisphosphate isomerase activity (GO:0043917)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.
Synonyms: ribose-1,5-bisphosphate isomerase activity
cadaverine aminopropyltransferase activity (GO:0043918)
Namespace: molecular_function
Definition: Catalysis of the reaction: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine = aminopropylcadaverine + H+ + S-methyl-5'-thioadenosine.
Synonyms: cadaverine aminopropyl transferase activity
agmatine aminopropyltransferase activity (GO:0043919)
Namespace: molecular_function
Definition: Catalysis of the reaction: agmatine + S-adenosyl 3-(methylsulfanyl)propylamine = H+ + N1-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine.
Synonyms: agmatine aminopropyl transferase activity
host-mediated perturbation of viral transcription (GO:0043921)
Namespace: biological_process
Definition: A process in which a host organism alters or subverts viral transcription.
Synonyms: modulation by host of viral transcription; regulation by host of viral transcription; regulation of viral transcription by host
host-mediated suppression of viral transcription (GO:0043922)
Namespace: biological_process
Definition: A process in which a host organism interferes with, inhibits or disrupts viral transcription.
Synonyms: negative regulation by host of viral transcription; negative regulation of viral transcription by host
host-mediated activation of viral transcription (GO:0043923)
Namespace: biological_process
Definition: A process in which a host organism initiates, promotes, or enhances the normal execution of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
Synonyms: positive regulation by host of viral transcription; positive regulation of viral transcription by host
suramin binding (GO:0043924)
Namespace: molecular_function
Definition: Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.
Synonyms: Germanin binding
obsolete exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay (GO:0043927)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap.
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
obsolete exonucleolytic catabolism of deadenylated mRNA (GO:0043928)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete primary ovarian follicle growth involved in primary follicle stage (GO:0043930)
Namespace: biological_process
Definition: OBSOLETE. Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis.
Synonyms: primary ovarian follicle growth during primary follicle stage
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
ossification involved in bone maturation (GO:0043931)
Namespace: biological_process
Definition: The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
Synonyms: ossification involved in bone modeling; ossification involved in skeletal development
ossification involved in bone remodeling (GO:0043932)
Namespace: biological_process
Definition: The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
Synonyms: ossification involved in bone remodelling
protein-containing complex organization (GO:0043933)
Namespace: biological_process
Definition: Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
Synonyms: cellular macromolecular complex organization; cellular macromolecular complex subunit organisation; cellular macromolecular complex subunit organization; macromolecular complex organization; macromolecular complex subunit organisation; macromolecular complex subunit organization; protein complex subunit organisation; protein complex subunit organization; protein-containing complex subunit organization
sporulation (GO:0043934)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.
sexual sporulation resulting in formation of a cellular spore (GO:0043935)
Namespace: biological_process
Definition: The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.
asexual sporulation resulting in formation of a cellular spore (GO:0043936)
Namespace: biological_process
Definition: The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction.
Synonyms: asexual reproduction resulting in the formation of a cellular spore; asexual sporulation resulting in the formation of a viable spore
regulation of sporulation (GO:0043937)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
positive regulation of sporulation (GO:0043938)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
negative regulation of sporulation (GO:0043939)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
regulation of sexual sporulation resulting in formation of a cellular spore (GO:0043940)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
positive regulation of sexual sporulation resulting in formation of a cellular spore (GO:0043941)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
negative regulation of sexual sporulation resulting in formation of a cellular spore (GO:0043942)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
regulation of asexual sporulation resulting in formation of a cellular spore (GO:0043943)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
negative regulation of asexual sporulation resulting in formation of a cellular spore (GO:0043944)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
positive regulation of asexual sporulation resulting in formation of a cellular spore (GO:0043945)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
obsolete positive regulation by host of symbiont catalytic activity (GO:0043947)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
Synonyms: activation by host of symbiont enzyme activity; activation of symbiont enzyme activity; positive regulation by host of symbiont enzyme activity; up regulation by host of symbiont enzyme activity; up-regulation by host of symbiont enzyme activity; upregulation by host of symbiont enzyme activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete induction by symbiont of host catalytic activity (GO:0043948)
Namespace: biological_process
Definition: OBSOLETE. Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: activation by symbiont of host enzyme activity; activation of host enzyme activity; positive regulation by symbiont of host catalytic activity; positive regulation by symbiont of host enzyme activity; up regulation by symbiont of host enzyme activity; up-regulation by symbiont of host enzyme activity; upregulation by symbiont of host enzyme activity
Comment: This term was obsoleted because it represents a molecular function.