LiteFold/GO huggingface dataset:
negative regulation of phosphatidylcholine catabolic process (GO:0010900)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
regulation of very-low-density lipoprotein particle remodeling (GO:0010901)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms: regulation of very-low-density lipoprotein particle remodelling; regulation of VLDL remodeling; regulation of VLDL remodelling
negative regulation of very-low-density lipoprotein particle remodeling (GO:0010903)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms: negative regulation of very-low-density lipoprotein particle remodelling; negative regulation of VLDL remodeling; negative regulation of VLDL remodelling
obsolete regulation of UDP-glucose catabolic process (GO:0010904)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
Synonyms: regulation of UDP-glucose catabolism
Comment: The reason for obsoletion is that this term is not clearly defined.
obsolete negative regulation of UDP-glucose catabolic process (GO:0010905)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
Synonyms: negative regulation of UDP-glucose catabolism
Comment: The reason for obsoletion is that this term is not clearly defined.
regulation of glucose metabolic process (GO:0010906)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
Synonyms: regulation of glucose metabolism
positive regulation of glucose metabolic process (GO:0010907)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
Synonyms: positive regulation of glucose metabolism
regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010908)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, which consists of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid.
positive regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010909)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, which consists of a core protein linked to a heparan sulfate glycosaminoglycan. The heparan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid.
obsolete positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity (GO:0010910)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of isomerase activity (GO:0010911)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of isomerase activity (GO:0010912)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
Comment: This term was obsoleted because it represents a molecular function.
regulation of sterigmatocystin biosynthetic process (GO:0010913)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
positive regulation of sterigmatocystin biosynthetic process (GO:0010914)
Namespace: biological_process
Definition: Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
regulation of very-low-density lipoprotein particle clearance (GO:0010915)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms: regulation of VLDL clearance; regulation of VLDL particle clearance
negative regulation of very-low-density lipoprotein particle clearance (GO:0010916)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms: negative regulation of VLDL clearance; negative regulation of VLDL particle clearance
negative regulation of mitochondrial membrane potential (GO:0010917)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
Synonyms: reduction of mitochondrial membrane potential
positive regulation of mitochondrial membrane potential (GO:0010918)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
Synonyms: elevation of mitochondrial membrane potential
regulation of inositol phosphate biosynthetic process (GO:0010919)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms: regulation of inositol phosphate biosynthesis
negative regulation of inositol phosphate biosynthetic process (GO:0010920)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms: negative regulation of inositol phosphate biosynthesis
regulation of phosphatase activity (GO:0010921)
Namespace: biological_process
Definition: Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing phosphate.
positive regulation of phosphatase activity (GO:0010922)
Namespace: biological_process
Definition: Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
negative regulation of phosphatase activity (GO:0010923)
Namespace: biological_process
Definition: Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
obsolete regulation of inositol-polyphosphate 5-phosphatase activity (GO:0010924)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of inositol-polyphosphate 5-phosphatase activity (GO:0010925)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
Comment: This term was obsoleted because it represents a molecular function.
cellular component assembly involved in morphogenesis (GO:0010927)
Namespace: biological_process
Definition: The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
regulation of auxin mediated signaling pathway (GO:0010928)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
Synonyms: regulation of auxin mediated signalling pathway
positive regulation of auxin mediated signaling pathway (GO:0010929)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
Synonyms: positive regulation of auxin mediated signalling pathway
negative regulation of auxin mediated signaling pathway (GO:0010930)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
Synonyms: negative regulation of auxin mediated signalling pathway
macrophage tolerance induction (GO:0010931)
Namespace: biological_process
Definition: A process involving any mechanism for tolerance induction in macrophages.
regulation of macrophage tolerance induction (GO:0010932)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.
positive regulation of macrophage tolerance induction (GO:0010933)
Namespace: biological_process
Definition: Any process that increases the frequency, rate, or extent of B cell tolerance induction.
macrophage cytokine production (GO:0010934)
Namespace: biological_process
Definition: The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
regulation of macrophage cytokine production (GO:0010935)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
negative regulation of macrophage cytokine production (GO:0010936)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
regulation of cytoplasmic microtubule depolymerization (GO:0010937)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.
cytoplasmic microtubule depolymerization (GO:0010938)
Namespace: biological_process
Definition: The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.
obsolete regulation of necrotic cell death (GO:0010939)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
Comment: This term was made obsolete because it represents a phenotype.
obsolete positive regulation of necrotic cell death (GO:0010940)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
Comment: This term was obsoleted because it represent a phenotype.
obsolete positive regulation of cell death (GO:0010942)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
Comment: The reason for obsoletion is that this term represent an assay and not a GO process.
NADPH pyrophosphatase activity (GO:0010943)
Namespace: molecular_function
Definition: Catalysis of the reaction: NADPH + H2O = NMNH + ADP.
obsolete negative regulation of transcription by competitive promoter binding (GO:0010944)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.
Comment: This term was obsoleted because it represents a mechanism and is outside the scope of GO.
coenzyme A diphosphatase activity (GO:0010945)
Namespace: molecular_function
Definition: Catalysis of the reaction: an acyl-coenzyme A or its derivatives + H2O = adenosine 3',5'-bisphosphate + an acyl-4'-phosphopantetheine + 2 H+. This reaction can also use coenzyme A as a substrate.
Synonyms: CoA diphosphatase activity; CoA pyrophosphatase activity; coenzyme A pyrophosphatase activity
regulation of meiotic joint molecule formation (GO:0010946)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
negative regulation of intestinal phytosterol absorption (GO:0010949)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.
positive regulation of endopeptidase activity (GO:0010950)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
negative regulation of endopeptidase activity (GO:0010951)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
positive regulation of peptidase activity (GO:0010952)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
positive regulation of protein processing (GO:0010954)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.
Synonyms: positive regulation of protein maturation by peptide bond cleavage
negative regulation of protein processing (GO:0010955)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
Synonyms: negative regulation of protein maturation by peptide bond cleavage
obsolete negative regulation of calcidiol 1-monooxygenase activity (GO:0010956)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
Comment: This term was obsoleted because it represents a molecular function.
negative regulation of vitamin D biosynthetic process (GO:0010957)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
regulation of amino acid import across plasma membrane (GO:0010958)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of amino acid import into a cell.
Synonyms: regulation of amino acid import
regulation of metal ion transport (GO:0010959)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
magnesium ion homeostasis (GO:0010960)
Namespace: biological_process
Definition: Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
intracellular magnesium ion homeostasis (GO:0010961)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a steady state level of magnesium ions within a cell.
Synonyms: cellular magnesium ion homeostasis
regulation of glucan biosynthetic process (GO:0010962)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
regulation of regulatory ncRNA-mediated heterochromatin formation (GO:0010964)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.
Synonyms: regulation of chromatin silencing by small RNA; regulation of heterochromatin assembly by small RNA; regulation of ncRNA-mediated heterochromatin formation; regulation of RNAi-mediated heterochromatin assembly; regulation of small non-coding RNA-mediated heterochromatin formation
regulation of mitotic sister chromatid separation (GO:0010965)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.
regulation of phosphate transport (GO:0010966)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of polyamine biosynthetic process (GO:0010967)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
regulation of microtubule nucleation (GO:0010968)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.