LiteFold/GO huggingface dataset:
DNA-binding transcription activator activity, RNA polymerase II-specific (GO:0001228)
Namespace: molecular_function
Definition: A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
Synonyms: copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription; distal enhancer DNA-binding transcription activator activity, RNA polymerase II-specific; metal ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription; metal ion regulated sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA-binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcriptional activator activity, copper ion regulated proximal promoter sequence-specific DNA binding; RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding; RNA polymerase II transcriptional activator activity, metal ion regulated proximal promoter sequence-specific DNA binding; RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding; RNA polymerase II transcriptional activator activity, zinc ion regulated proximal promoter sequence-specific DNA binding; sequence-specific distal enhancer binding RNA polymerase II transcription factor activity involved in positive regulation of transcription; transcriptional activator activity, metal ion regulated sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding; zinc ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity involved in positive regulation of transcription
Comment: For usage guidance, see comment in GO:0003700 ; DNA-binding transcription factor activity.
obsolete chronological cell aging (GO:0001300)
Namespace: biological_process
Definition: OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.
Synonyms: chronological cell ageing
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
obsolete progressive alteration of chromatin involved in cell aging (GO:0001301)
Namespace: biological_process
Definition: OBSOLETE. Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.
Synonyms: age-dependent accumulation of genetic damage; progressive alteration of chromatin during cell ageing; progressive alteration of chromatin during cell aging
Comment: This term was obsoleted because it represents a phenotype.
obsolete replicative cell aging (GO:0001302)
Namespace: biological_process
Definition: OBSOLETE. The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.
Synonyms: replicative cell ageing
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete nucleolar fragmentation involved in replicative aging (GO:0001303)
Namespace: biological_process
Definition: OBSOLETE. A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells.
Synonyms: nucleolar fragmentation during replicative ageing; nucleolar fragmentation during replicative aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete progressive alteration of chromatin involved in chronological cell aging (GO:0001305)
Namespace: biological_process
Definition: OBSOLETE. A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells.
Synonyms: progressive alteration of chromatin during chronological cell ageing; progressive alteration of chromatin during chronological cell aging
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging (GO:0001307)
Namespace: biological_process
Definition: OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
Synonyms: extrachromosomal circular DNA accumulation during replicative cell ageing; extrachromosomal circular DNA accumulation during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete negative regulation of chromatin silencing involved in replicative cell aging (GO:0001308)
Namespace: biological_process
Definition: OBSOLETE. The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.
Synonyms: loss of chromatin silencing during replicative cell ageing; loss of chromatin silencing involved in replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete age-dependent telomere shortening (GO:0001309)
Namespace: biological_process
Definition: OBSOLETE. Progressive reduction in length of the telomeres, the termini of eukaryotic chromosomes, that occurs as part of the cellular aging process.
Synonyms: age-dependent telomere shortening
Comment: This term was made obsolete because it represents a phenotype.
obsolete extrachromosomal rDNA circle accumulation involved in replicative cell aging (GO:0001310)
Namespace: biological_process
Definition: OBSOLETE. Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
Synonyms: extrachromosomal rDNA circle accumulation during replicative cell ageing; extrachromosomal rDNA circle accumulation during replicative cell aging; extrachromosomal ribosomal DNA circle accumulation during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging (GO:0001311)
Namespace: biological_process
Definition: OBSOLETE. Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.
Synonyms: assembly of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging; formation of extrachromosomal circular rDNA by homologous recombination during replicative cell ageing; formation of extrachromosomal circular rDNA by homologous recombination during replicative cell aging; formation of extrachromosomal circular ribosomal DNA by homologous recombination during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete replication of extrachromosomal rDNA circles involved in replicative cell aging (GO:0001312)
Namespace: biological_process
Definition: OBSOLETE. Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication.
Synonyms: replication of extrachromosomal rDNA circles during replicative cell ageing; replication of extrachromosomal rDNA circles during replicative cell aging; replication of extrachromosomal ribosomal DNA circles during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete formation of extrachromosomal circular DNA involved in replicative cell aging (GO:0001313)
Namespace: biological_process
Definition: OBSOLETE. Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age.
Synonyms: assembly of extrachromosomal circular DNA involved in replicative cell aging; formation of extrachromosomal circular DNA during replicative cell ageing; formation of extrachromosomal circular DNA during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete replication of extrachromosomal circular DNA involved in replicative cell aging (GO:0001314)
Namespace: biological_process
Definition: OBSOLETE. Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
Synonyms: replication of extrachromosomal circular DNA during replicative cell ageing; replication of extrachromosomal circular DNA during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete age-dependent response to reactive oxygen species (GO:0001315)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
Synonyms: age-dependent response to active oxygen species; age-dependent response to AOS; age-dependent response to reactive oxidative species; age-dependent response to reactive oxygen intermediate; age-dependent response to ROI; age-dependent response to ROS
Comment: This term was obsoleted because it represents a phenotype.
obsolete age-dependent response to reactive oxygen species involved in replicative cell aging (GO:0001316)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
Synonyms: age-dependent response to active oxygen species during replicative cell aging; age-dependent response to AOS during replicative cell aging; age-dependent response to reactive oxidative species during replicative cell aging; age-dependent response to reactive oxygen intermediate during replicative cell aging; age-dependent response to reactive oxygen species during replicative cell ageing; age-dependent response to reactive oxygen species during replicative cell aging; age-dependent response to ROI during replicative cell aging; age-dependent response to ROS during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete accumulation of oxidatively modified proteins involved in replicative cell aging (GO:0001317)
Namespace: biological_process
Definition: OBSOLETE. Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.
Synonyms: accumulation of oxidatively modified proteins during replicative cell ageing; accumulation of oxidatively modified proteins during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete formation of oxidatively modified proteins involved in replicative cell aging (GO:0001318)
Namespace: biological_process
Definition: OBSOLETE. Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.
Synonyms: formation of oxidatively modified proteins during replicative cell ageing; formation of oxidatively modified proteins during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete inheritance of oxidatively modified proteins involved in replicative cell aging (GO:0001319)
Namespace: biological_process
Definition: OBSOLETE. A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.
Synonyms: inheritance of oxidatively modified proteins during replicative cell ageing; inheritance of oxidatively modified proteins during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete age-dependent response to reactive oxygen species involved in chronological cell aging (GO:0001320)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
Synonyms: age-dependent response to active oxygen species during chronological cell aging; age-dependent response to AOS during chronological cell aging; age-dependent response to reactive oxidative species during chronological cell aging; age-dependent response to reactive oxygen intermediate during chronological cell aging; age-dependent response to reactive oxygen species during chronological cell ageing; age-dependent response to reactive oxygen species during chronological cell aging; age-dependent response to ROI during chronological cell aging; age-dependent response to ROS during chronological cell aging
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
obsolete age-dependent general metabolic decline involved in replicative cell aging (GO:0001321)
Namespace: biological_process
Definition: OBSOLETE. A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.
Synonyms: age-dependent general metabolic decline during replicative cell ageing; age-dependent general metabolic decline involved in replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete age-dependent response to oxidative stress involved in replicative cell aging (GO:0001322)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.
Synonyms: age-dependent response to oxidative stress during replicative cell ageing; age-dependent response to oxidative stress during replicative cell aging
Comment: This term was obsoleted because it represents an assay, not a true biological process.
obsolete age-dependent general metabolic decline involved in chronological cell aging (GO:0001323)
Namespace: biological_process
Definition: OBSOLETE. A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.
Synonyms: age-dependent general metabolic decline during chronological cell ageing; age-dependent general metabolic decline during chronological cell aging
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
obsolete age-dependent response to oxidative stress involved in chronological cell aging (GO:0001324)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.
Synonyms: age-dependent response to oxidative stress during chronological cell ageing; age-dependent response to oxidative stress during chronological cell aging
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
formation of extrachromosomal circular DNA (GO:0001325)
Namespace: biological_process
Definition: Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
Synonyms: assembly of extrachromosomal circular DNA
replication of extrachromosomal circular DNA (GO:0001326)
Namespace: biological_process
Definition: Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
mating projection base (GO:0001400)
Namespace: cellular_component
Definition: The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.
Synonyms: base of shmoo tip; conjugation tube base
SAM complex (GO:0001401)
Namespace: cellular_component
Definition: A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.
Synonyms: mitochondrial sorting and assembly machinery complex; TOB complex
Comment: See also the cellular component term 'mitochondrial outer membrane translocase complex ; GO:0005742'.
invasive growth in response to glucose limitation (GO:0001403)
Namespace: biological_process
Definition: A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
Synonyms: colony morphology
Comment: Note that this term should not be used to describe the invasion of host tissues by pathogenic organisms, which is described by the biological process term 'entry into host ; GO:0044409', nor should it be used to describe growth of diseased cells of an organism into the surrounding normal tissue, which is outside of the scope of GO.
obsolete invasive growth (GO:0001404)
Namespace: biological_process
Definition: OBSOLETE. Growth of a pathogenic organism that results in penetration into cells or tissues of the host organism. This often (but not necessarily) includes a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue.
Synonyms: invasive growth; tissue invasion
Comment: This term was made obsolete because more appropriate terms were created.
PAM complex, Tim23 associated import motor (GO:0001405)
Namespace: cellular_component
Definition: Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.
Synonyms: mitochondrial import motor; PAM complex; pre-sequence translocase-associated import motor; presequence translocase-associated import motor
glycerophosphodiester transmembrane transporter activity (GO:0001406)
Namespace: molecular_function
Definition: Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
glycerophosphodiester transmembrane transport (GO:0001407)
Namespace: biological_process
Definition: The process in which a glycerophosphodiester is transported across a membrane. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
guanine nucleotide transport (GO:0001408)
Namespace: biological_process
Definition: The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
hyphal tip (GO:0001411)
Namespace: cellular_component
Definition: The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
skeletal system development (GO:0001501)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
Synonyms: skeletal development
cartilage condensation (GO:0001502)
Namespace: biological_process
Definition: The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
neurotransmitter uptake (GO:0001504)
Namespace: biological_process
Definition: The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
Synonyms: neurotransmitter import; neurotransmitter import into glial cell; neurotransmitter import into neuron; neurotransmitter recycling
obsolete regulation of neurotransmitter levels (GO:0001505)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates levels of neurotransmitter.
Comment: The reason for obsoletion is that 'neurotransmitter' is unnecessary grouping in the metabolism branch of the ontology, and it creates true path violations.
obsolete neurotransmitter biosynthetic process and storage (GO:0001506)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of neurotransmitters and the storage of the synthesized molecules.
Synonyms: neurotransmitter anabolism and storage; neurotransmitter biosynthetic process and storage; neurotransmitter formation and storage; neurotransmitter synthesis and storage
Comment: This term was made obsolete because it is an amalgamation of its two children.