LiteFold/GO huggingface dataset:
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
Synonyms: cross presentation; cross-presentation; exogenous peptide antigen processing and presentation via MHC class I, TAP-dependent; TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-dependent exogenous peptide antigen processing and presentation via MHC class I
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (GO:0002480)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.
Synonyms: cross presentation; cross-presentation; exogenous peptide antigen processing and presentation via MHC class I, TAP-independent; TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class I; TAP-independent exogenous peptide antigen processing and presentation via MHC class I
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent (GO:0002481)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms: exogenous peptide antigen processing and presentation via MHC class Ib, TAP-dependent; TAP-dependent antigen processing and presentation of exogenous peptide antigen via MHC class Ib; TAP-dependent exogenous peptide antigen processing and presentation via MHC class Ib
antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent (GO:0002482)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms: exogenous peptide antigen processing and presentation via MHC class Ib, TAP-independent; TAP-independent antigen processing and presentation of exogenous peptide antigen via MHC class Ib; TAP-independent exogenous peptide antigen processing and presentation via MHC class Ib
antigen processing and presentation of endogenous peptide antigen (GO:0002483)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
Synonyms: endogenous peptide antigen processing and presentation
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway (GO:0002484)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
Synonyms: endogenous peptide antigen processing and presentation via MHC class I via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (GO:0002485)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
Synonyms: endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-dependent; TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway; TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway (GO:0002487)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.
Synonyms: endogenous peptide antigen processing and presentation via MHC class I via endolysosomal pathway
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway (GO:0002488)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms: endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (GO:0002489)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms: endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-dependent; TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway; TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent (GO:0002490)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
Synonyms: endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway, TAP-independent; TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway; TAP-independent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
peptide antigen assembly with MHC class Ib protein complex (GO:0002492)
Namespace: biological_process
Definition: The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
lipid antigen assembly with MHC class Ib protein complex (GO:0002493)
Namespace: biological_process
Definition: The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.
lipid antigen transport (GO:0002494)
Namespace: biological_process
Definition: The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
antigen processing and presentation of peptide antigen via MHC class II (GO:0002495)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
Synonyms: peptide antigen processing and presentation via MHC class II
proteolysis associated with antigen processing and presentation (GO:0002496)
Namespace: biological_process
Definition: The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
proteasomal proteolysis associated with antigen processing and presentation (GO:0002497)
Namespace: biological_process
Definition: The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.
proteolysis within endoplasmic reticulum associated with antigen processing and presentation (GO:0002498)
Namespace: biological_process
Definition: The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
Synonyms: endoplasmic reticulum proteolysis associated with antigen processing and presentation; ER proteolysis associated with antigen processing and presentation; proteolysis within ER associated with antigen processing and presentation
proteolysis within endosome associated with antigen processing and presentation (GO:0002499)
Namespace: biological_process
Definition: The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
Synonyms: endosomal proteolysis associated with antigen processing and presentation
proteolysis within lysosome associated with antigen processing and presentation (GO:0002500)
Namespace: biological_process
Definition: The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
Synonyms: lysosomal proteolysis associated with antigen processing and presentation
peptide antigen assembly with MHC protein complex (GO:0002501)
Namespace: biological_process
Definition: The binding of a peptide to the antigen binding groove of an MHC protein complex.
peptide antigen assembly with MHC class I protein complex (GO:0002502)
Namespace: biological_process
Definition: The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.
peptide antigen assembly with MHC class II protein complex (GO:0002503)
Namespace: biological_process
Definition: The binding of a peptide to the antigen binding groove of an MHC class II protein complex.
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
Synonyms: peptide or polysaccharide antigen processing and presentation of via MHC class II
antigen processing and presentation of polysaccharide antigen via MHC class II (GO:0002505)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
Synonyms: polysaccharide antigen processing and presentation via MHC class II
tolerance induction (GO:0002507)
Namespace: biological_process
Definition: A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
central tolerance induction (GO:0002508)
Namespace: biological_process
Definition: Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
central tolerance induction to self antigen (GO:0002509)
Namespace: biological_process
Definition: Tolerance induction in the central lymphoid organs directed at self antigens.
central B cell tolerance induction (GO:0002510)
Namespace: biological_process
Definition: Tolerance induction of B cells in the bone marrow.
Synonyms: central B lymphocyte tolerance induction; central B-cell tolerance induction; central B-lymphocyte tolerance induction
central B cell receptor editing (GO:0002511)
Namespace: biological_process
Definition: Receptor editing occurring in B cells in the bone marrow.
Synonyms: central B lymphocyte receptor editing; central B-cell receptor editing; central B-lymphocyte receptor editing
central T cell tolerance induction (GO:0002512)
Namespace: biological_process
Definition: Tolerance induction of T cells in the thymus.
Synonyms: central T lymphocyte tolerance induction; central T-cell tolerance induction; central T-lymphocyte tolerance induction
tolerance induction to self antigen (GO:0002513)
Namespace: biological_process
Definition: Tolerance induction directed at self antigens.
B cell tolerance induction (GO:0002514)
Namespace: biological_process
Definition: A process involving any mechanism for tolerance induction in B cells.
Synonyms: B lymphocyte tolerance induction; B-cell tolerance induction; B-lymphocyte tolerance induction
B cell anergy (GO:0002515)
Namespace: biological_process
Definition: Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
Synonyms: B lymphocyte anergy; B-cell anergy; B-lymphocyte anergy
B cell deletion (GO:0002516)
Namespace: biological_process
Definition: The apoptotic death of B cells which is part of B cell tolerance induction.
Synonyms: B lymphocyte deletion; B-cell deletion; B-lymphocyte deletion
T cell tolerance induction (GO:0002517)
Namespace: biological_process
Definition: A process involving any mechanism for tolerance induction in T cells.
Synonyms: T lymphocyte tolerance induction; T-cell tolerance induction; T-lymphocyte tolerance induction
lymphocyte chemotaxis across high endothelial venule (GO:0002518)
Namespace: biological_process
Definition: The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.
natural killer cell tolerance induction (GO:0002519)
Namespace: biological_process
Definition: Tolerance induction of natural killer cells.
Synonyms: NK cell tolerance induction
immune system development (GO:0002520)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
leukocyte differentiation (GO:0002521)
Namespace: biological_process
Definition: The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
Synonyms: immune cell differentiation; leucocyte differentiation
leukocyte migration involved in immune response (GO:0002522)
Namespace: biological_process
Definition: The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.
Synonyms: immune cell migration during immune response; immune cell trafficking during immune response; leucocyte migration during immune response; leucocyte trafficking during immune response; leukocyte trafficking during immune response
leukocyte migration involved in inflammatory response (GO:0002523)
Namespace: biological_process
Definition: The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
Synonyms: immune cell migration during inflammatory response; immune cell trafficking during inflammatory response; leucocyte migration during inflammatory response; leucocyte trafficking during inflammatory response; leukocyte migration during inflammatory response; leukocyte trafficking during inflammatory response
hypersensitivity (GO:0002524)
Namespace: biological_process
Definition: An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
Synonyms: hypersensitivity response
acute inflammatory response to non-antigenic stimulus (GO:0002525)
Namespace: biological_process
Definition: An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
acute inflammatory response (GO:0002526)
Namespace: biological_process
Definition: Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
obsolete vasodilation involved in acute inflammatory response (GO:0002527)
Namespace: biological_process
Definition: OBSOLETE. An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.
Synonyms: vasodilation during acute inflammatory response
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of vascular permeability involved in acute inflammatory response (GO:0002528)
Namespace: biological_process
Definition: Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.
Synonyms: regulation of vascular permeability during acute inflammatory response
regulation of plasma kallikrein-kinin cascade (GO:0002529)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
production of molecular mediator involved in inflammatory response (GO:0002532)
Namespace: biological_process
Definition: The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: production of cellular mediator of acute inflammation; production of molecular mediator involved in acute inflammatory response
obsolete lysosomal enzyme secretion involved in inflammatory response (GO:0002533)
Namespace: biological_process
Definition: OBSOLETE. The regulated release of lysosomal enzymes by a cell as part of an inflammatory response.
Synonyms: lysosomal enzyme secretion involved in acute inflammatory response; secretion of lysosomal enzymes involved in acute inflammatory response; secretion of lysosomal enzymes involved in inflammatory response
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
cytokine production involved in inflammatory response (GO:0002534)
Namespace: biological_process
Definition: The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
Synonyms: cytokine production involved in acute inflammatory response
respiratory burst involved in inflammatory response (GO:0002536)
Namespace: biological_process
Definition: A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
Synonyms: oxidative burst during acute inflammatory response; production of reactive oxygen species during acute inflammatory response; respiratory burst involved in acute inflammatory response
nitric oxide production involved in inflammatory response (GO:0002537)
Namespace: biological_process
Definition: The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
Synonyms: nitric oxide production involved in acute inflammatory response; production of nitric oxide involved in acute inflammatory response; production of nitric oxide involved in inflammatory response
arachidonate metabolite production involved in inflammatory response (GO:0002538)
Namespace: biological_process
Definition: The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.
Synonyms: arachidonic acid metabolite production involved in acute inflammatory response; arachidonic acid metabolite production involved in inflammatory response; production of arachidonic acid metabolites involved in acute inflammatory response; production of arachidonic acid metabolites involved in inflammatory response
prostaglandin production involved in inflammatory response (GO:0002539)
Namespace: biological_process
Definition: The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
Synonyms: prostaglandin production involved in acute inflammatory response