LiteFold/GO huggingface dataset:
regulation of long-chain fatty acid import across plasma membrane (GO:0010746)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: regulation of plasma membrane long-chain fatty acid transport
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
positive regulation of long-chain fatty acid import across plasma membrane (GO:0010747)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: positive regulation of plasma membrane long-chain fatty acid transport
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
negative regulation of long-chain fatty acid import across plasma membrane (GO:0010748)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.
Synonyms: negative regulation of plasma membrane long-chain fatty acid transport
regulation of nitric oxide mediated signal transduction (GO:0010749)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
Synonyms: regulation of nitric oxide-mediated signal transduction
positive regulation of nitric oxide mediated signal transduction (GO:0010750)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is The series of molecular signals mediated by the detection of nitric oxide (NO).
Synonyms: positive regulation of nitric oxide-mediated signal transduction
obsolete regulation of cGMP-mediated signaling (GO:0010752)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of cGMP-mediated signaling.
Synonyms: regulation of cGMP-mediated signalling
Comment: This term was obsoleted because it does not represents the regulation of a specific pathway; many pathways use cGMP as a second messenger.
negative regulation of receptor guanylyl cyclase signaling pathway (GO:0010754)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of receptor guanylyl cyclase signaling pathway.
Synonyms: negative regulation of cGMP-mediated signaling; negative regulation of cGMP-mediated signalling
regulation of plasminogen activation (GO:0010755)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
positive regulation of plasminogen activation (GO:0010756)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
regulation of macrophage chemotaxis (GO:0010758)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
positive regulation of macrophage chemotaxis (GO:0010759)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
negative regulation of macrophage chemotaxis (GO:0010760)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
fibroblast migration (GO:0010761)
Namespace: biological_process
Definition: Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
Synonyms: fibroblast cell migration
regulation of fibroblast migration (GO:0010762)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
Synonyms: regulation of fibroblast cell migration
positive regulation of fibroblast migration (GO:0010763)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
Synonyms: positive regulation of fibroblast cell migration
negative regulation of fibroblast migration (GO:0010764)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
Synonyms: negative regulation of fibroblast cell migration
positive regulation of sodium ion transport (GO:0010765)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
negative regulation of sodium ion transport (GO:0010766)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
obsolete regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage (GO:0010767)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage (GO:0010768)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
Comment: This term was obsoleted because it represents a GO-CAM model.
positive regulation of cell morphogenesis (GO:0010770)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
negative regulation of cell morphogenesis (GO:0010771)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
meiotic DNA recombinase assembly involved in reciprocal meiotic recombination (GO:0010772)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
obsolete meiotic DNA recombinase assembly involved in meiotic gene conversion (GO:0010773)
Namespace: biological_process
Definition: OBSOLETE. The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
meiotic strand invasion involved in reciprocal meiotic recombination (GO:0010774)
Namespace: biological_process
Definition: The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
obsolete meiotic strand invasion involved in meiotic gene conversion (GO:0010775)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete meiotic mismatch repair involved in meiotic gene conversion (GO:0010776)
Namespace: biological_process
Definition: OBSOLETE. A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
meiotic mismatch repair involved in reciprocal meiotic recombination (GO:0010777)
Namespace: biological_process
Definition: A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
meiotic DNA repair synthesis involved in reciprocal meiotic recombination (GO:0010778)
Namespace: biological_process
Definition: The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
obsolete meiotic DNA repair synthesis involved in meiotic gene conversion (GO:0010779)
Namespace: biological_process
Definition: OBSOLETE. The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
meiotic DNA double-strand break formation involved in reciprocal meiotic recombination (GO:0010780)
Namespace: biological_process
Definition: The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
obsolete meiotic DNA double-strand break formation involved in meiotic gene conversion (GO:0010781)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
proboscis morphogenesis, eye-antennal disc-derived (GO:0010783)
Namespace: biological_process
Definition: The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.
proboscis morphogenesis, clypeo-labral disc-derived (GO:0010784)
Namespace: biological_process
Definition: The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.
clathrin coating of Golgi vesicle, plasma membrane to endosome targeting (GO:0010785)
Namespace: biological_process
Definition: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.
clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting (GO:0010786)
Namespace: biological_process
Definition: The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.
COPI coating of Golgi vesicle, inter-Golgi cisterna (GO:0010787)
Namespace: biological_process
Definition: The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.
COPI coating of Golgi vesicle, cis-Golgi to rough ER (GO:0010788)
Namespace: biological_process
Definition: The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.
meiosis II sister chromatid cohesion (GO:0010790)
Namespace: biological_process
Definition: The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.
Synonyms: meiotic sister chromatid cohesion involved in meiosis II
DNA double-strand break processing involved in repair via single-strand annealing (GO:0010792)
Namespace: biological_process
Definition: The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.
regulation of mRNA export from nucleus (GO:0010793)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.
regulation of ubiquinone biosynthetic process (GO:0010795)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
obsolete regulation of multivesicular body size (GO:0010796)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.
Comment: The reason for obsoletion is that this term represents an assay and not a real GO process.
obsolete regulation of multivesicular body size involved in endosome transport (GO:0010797)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.
Comment: The reason for obsoletion is that this term represents an assay and not a real GO process.
obsolete regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism (GO:0010798)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.
Comment: The reason for obsoletion is that this term represents an assay and not a real GO process.
regulation of peptidyl-threonine phosphorylation (GO:0010799)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
positive regulation of peptidyl-threonine phosphorylation (GO:0010800)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
regulation of synaptic vesicle priming (GO:0010807)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
positive regulation of synaptic vesicle priming (GO:0010808)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
negative regulation of synaptic vesicle priming (GO:0010809)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
regulation of cell-substrate adhesion (GO:0010810)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
positive regulation of cell-substrate adhesion (GO:0010811)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
neuropeptide catabolic process (GO:0010813)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.
substance P catabolic process (GO:0010814)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.
bradykinin catabolic process (GO:0010815)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.
calcitonin catabolic process (GO:0010816)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.
regulation of hormone levels (GO:0010817)
Namespace: biological_process
Definition: Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.
T cell chemotaxis (GO:0010818)
Namespace: biological_process
Definition: The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
Synonyms: T-cell chemotaxis
regulation of T cell chemotaxis (GO:0010819)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
positive regulation of T cell chemotaxis (GO:0010820)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
regulation of mitochondrion organization (GO:0010821)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
Synonyms: regulation of mitochondrion organisation
obsolete positive regulation of mitochondrion organization (GO:0010822)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
Synonyms: positive regulation of mitochondrion organisation
Comment: The reason for obsoletion is that the meaning of the term is ambiguous.
obsolete negative regulation of mitochondrion organization (GO:0010823)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
Synonyms: negative regulation of mitochondrion organisation
regulation of centrosome duplication (GO:0010824)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
positive regulation of centrosome duplication (GO:0010825)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
negative regulation of centrosome duplication (GO:0010826)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.