LiteFold/GO huggingface dataset:
Entner-Doudoroff pathway through gluconate (GO:0061679)
Namespace: biological_process
Definition: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.
Synonyms: gluconate pathway
Entner-Doudoroff pathway through gluconate to D-glyceraldehyde (GO:0061680)
Namespace: biological_process
Definition: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.
Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate (GO:0061681)
Namespace: biological_process
Definition: The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.
seminal vesicle morphogenesis (GO:0061682)
Namespace: biological_process
Definition: The process in which the anatomical structures of a seminal vesicle are generated and organized.
obsolete branching involved in seminal vesicle morphogenesis (GO:0061683)
Namespace: biological_process
Definition: OBSOLETE. The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.
Synonyms: gonecyst branching morphogenesis; seminal gland branching morphogenesis; seminal vesicle branching; seminal vesicle branching morphogenesis
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
chaperone-mediated autophagy (GO:0061684)
Namespace: biological_process
Definition: The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
Synonyms: CASA; chaperone-assisted selective autophagy; CMA
diphthine methylesterase activity (GO:0061685)
Namespace: molecular_function
Definition: Catalysis of the reaction: diphthine methyl ester + H2O = diphthine + H+ + methanol.
hercynylcysteine sulfoxide synthase activity (GO:0061686)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (hercynine) + O2 = hercynylcysteine sulfoxide + H2O.
Synonyms: hercynylcysteine S-oxide synthase; hercynylcysteine sulfoxide synthase
detoxification of inorganic compound (GO:0061687)
Namespace: biological_process
Definition: Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.
glycolytic process via Entner-Doudoroff Pathway (GO:0061688)
Namespace: biological_process
Definition: A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.
Synonyms: gluconate pathway
tricellular tight junction (GO:0061689)
Namespace: cellular_component
Definition: An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.
lipoamidase activity (GO:0061690)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] = (R)-lipoate + L-lysyl-[lipoyl-carrier protein].
Synonyms: lipoyl-X-hydrolase
detoxification of hydrogen peroxide (GO:0061691)
Namespace: biological_process
Definition: Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
cellular detoxification of hydrogen peroxide (GO:0061692)
Namespace: biological_process
Definition: Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex (GO:0061694)
Namespace: cellular_component
Definition: A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.
Comment: An example of this complex is PhnI (P16687) in Escherichia coli.
transferase complex, transferring phosphorus-containing groups (GO:0061695)
Namespace: cellular_component
Definition: A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
pituitary gonadotropin complex (GO:0061696)
Namespace: cellular_component
Definition: A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.
protein-glutaryllysine deglutarylase activity (GO:0061697)
Namespace: molecular_function
Definition: Catalysis of the reaction: N(6)-glutaryl-L-lysyl-[protein] + NAD+ + H2O = 2''-O-glutaryl-ADP-D-ribose + nicotinamide + L-lysyl-[protein].
Comment: This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide.
protein deglutarylation (GO:0061698)
Namespace: biological_process
Definition: The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.
obsolete peptidyl-lysine deglutarylation (GO:0061699)
Namespace: biological_process
Definition: OBSOLETE. The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.
Comment: This term was obsoleted because it represents a molecular function.
GATOR2 complex (GO:0061700)
Namespace: cellular_component
Definition: A multiprotein subcomplex of the GATOR complex that regulates TORC1 signaling by interacting with the Rag GTPase. In human, this complex consists of WDR24, WDR59, MIOS, SEH1L, and SEC13. In S. cerevisiae, this complex is referred to as SEACAT and contains the Sea2p, Sea3p, Sea4p, Seh1p, Sec13p proteins.
Synonyms: SEACAT complex
Comment: The Rag GTPase complex corresponds to Gtr1-Gtr2 GTPase complex ; GO:1990131.
bacterial outer membrane vesicle (GO:0061701)
Namespace: cellular_component
Definition: A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.
canonical inflammasome complex (GO:0061702)
Namespace: cellular_component
Definition: A cytosolic protein complex that is capable of activating caspase-1.
pyroptosome complex (GO:0061703)
Namespace: cellular_component
Definition: A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.
Synonyms: ASC pyroptosome
glycolytic process from sucrose (GO:0061704)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
sucrose catabolic process to fructose-6-phosphate through glucose and fructose (GO:0061705)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.
glycolytic process from sucrose through glucose and fructose (GO:0061706)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
extracellular exosome macropinocytosis (GO:0061707)
Namespace: biological_process
Definition: The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.
tRNA-5-taurinomethyluridine 2-sulfurtransferase activity (GO:0061708)
Namespace: molecular_function
Definition: Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.
reticulophagy (GO:0061709)
Namespace: biological_process
Definition: The selective autohagy process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.
Synonyms: autophagy of the endoplasmic reticulum; autophagy of the ER; endoplasmic reticulum autophagy; endoplasmic reticulum degradation; ER autophagy; ER degradation; ER-phagy
L-threonylcarbamoyladenylate synthase activity (GO:0061710)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O.
tRNA N(6)-L-threonylcarbamoyladenine synthase activity (GO:0061711)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.
Synonyms: N(6)-L-threonylcarbamoyladenine synthase activity; t6A synthase activity
obsolete tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase (GO:0061712)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.
Comment: The reason for obsoletion is that this term is equivalent to N6-threonylcarbomyladenosine methylthiotransferase activity.
anterior neural tube closure (GO:0061713)
Namespace: biological_process
Definition: The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.
folic acid receptor activity (GO:0061714)
Namespace: molecular_function
Definition: Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.
Synonyms: folate receptor activity
obsolete miRNA 2'-O-methylation (GO:0061715)
Namespace: biological_process
Definition: OBSOLETE. The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule.
Comment: This term was obsoleted because it represents a molecular function.
miRNA export from nucleus (GO:0061716)
Namespace: biological_process
Definition: The directed movement of a processed miRNA from the nucleus to the cytoplasm.
glucose catabolic process to pyruvate (GO:0061718)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.
Synonyms: glucose catabolism to pyruvate
glucose catabolic process to pyruvate utilizing ADP (GO:0061719)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.
6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde (GO:0061720)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-) (GO:0061721)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).
sulphoglycolysis (GO:0061722)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.
Synonyms: sulfoglycolysis
glycophagy (GO:0061723)
Namespace: biological_process
Definition: The selective degradation of glycogen by macroautophagy.
lipophagy (GO:0061724)
Namespace: biological_process
Definition: The selective degradation of lipid droplets by macroautophagy.
cytosolic lipolysis (GO:0061725)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.
obsolete mitochondrion disassembly (GO:0061726)
Namespace: biological_process
Definition: OBSOLETE. The disaggregation of a mitochondrion into its constituent components.
Synonyms: mitochondrion degradation
Comment: This term is obsoleted because it was an unnecessary grouping class
GDP-mannose biosynthetic process from mannose (GO:0061728)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.
GDP-D-mannose biosynthetic process from fructose-6-phosphate (GO:0061729)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of GDP-D-mannose from D-fructose-6-phosphate.
Synonyms: GDP-mannose biosynthetic process from fructose-6-phosphate; GDP-mannose biosynthetic process from glucose
C-rich strand telomeric DNA binding (GO:0061730)
Namespace: molecular_function
Definition: Binding to C-rich, single-stranded, telomere-associated DNA.
ribonucleoside-diphosphate reductase activity (GO:0061731)
Namespace: molecular_function
Definition: Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
Synonyms: adenosylcobalamin-dependent ribonucleotide reductase activity; aerobic non-heme iron-dependent ribonucleotide reductase activity; anaerobic iron-sulfur-dependent ribonucleotide reductase activity; class I ribonucleotide reductase activity; class II ribonucleoside-diphosphate reductase activity; class II ribonucleotide reductase activity; class III ribonucleotide reductase activity; nucleoside diphosphate reductase activity; purine/pyrimidine nucleoside diphosphate reduction; ribonucleoside 5'-diphosphate reductase activity; ribonucleotide diphosphate reductase activity; ribonucleotide reductase activity; RNR
obsolete mitochondrial acetyl-CoA biosynthetic process from pyruvate (GO:0061732)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.
Comment: This term was obsoleted because it was representing the same process as its parent.
protein-lysine-acetyltransferase activity (GO:0061733)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-lysyl-[protein] + acetyl-CoA = N6-acetyl-L-lysyl-[protein] + CoA + H+.
Synonyms: peptide-lysine-acetyltransferase activity; peptide-lysine-N-acetylase activity; peptide-lysine-N-acetyltransferase activity; protein acetylase activity; protein acetyltransferase activity; protein-lysine-N-acetylase activity
type 2 mitophagy (GO:0061734)
Namespace: biological_process
Definition: The selective autophagy process in which a mitochondrion is degraded by macroautophagy in a process initiated by mitochondrial depolarization (mtDepo) followed by Parkin binding, and ubiquitination of outer membrane proteins, to remove potentially harm-inducing dysfunctional/damaged mitochondria.
Synonyms: Park2-mediated mitophagy in response to mitochondrial depolarization; parkin-mediated mitophagy in response to mitochondrial depolarization; PRKN-mediated mitophagy in response to mitochondrial depolarization
obsolete DNM1L-mediated stimulation of mitophagy in response to mitochondrial depolarization (GO:0061735)
Namespace: biological_process
Definition: OBSOLETE. A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a DNM1L-family molecule.
Synonyms: dynamin-like protein-mediated stimulation of mitophagy in response to mitochondrial depolarization
Comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using another term
engulfment of target by autophagosome (GO:0061736)
Namespace: biological_process
Definition: The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.
leukotriene signaling pathway (GO:0061737)
Namespace: biological_process
Definition: A G protein-coupled receptor signaling pathway initiated by leukotriene binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.
late endosomal microautophagy (GO:0061738)
Namespace: biological_process
Definition: The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.
protein lipidation involved in autophagosome assembly (GO:0061739)
Namespace: biological_process
Definition: The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.
protein targeting to lysosome involved in chaperone-mediated autophagy (GO:0061740)
Namespace: biological_process
Definition: The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.
obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy (GO:0061741)
Namespace: biological_process
Definition: OBSOLETE. The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy.
Comment: This term was obsoleted because it represents a function within a process.
chaperone-mediated autophagy translocation complex (GO:0061742)
Namespace: cellular_component
Definition: A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.
Synonyms: chaperone-mediated autophagy receptor complex; CMA receptor complex; CMA translocation complex
motor learning (GO:0061743)
Namespace: biological_process
Definition: Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.
motor behavior (GO:0061744)
Namespace: biological_process
Definition: The specific neuromuscular movement of a single organism in response to external or internal stimuli.
forked DNA-dependent helicase activity (GO:0061749)
Namespace: molecular_function
Definition: Unwinding a DNA helix containing forked DNA, driven by ATP hydrolysis.
acid sphingomyelin phosphodiesterase activity (GO:0061750)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in an acidic environment.
Synonyms: acid SMase; acid sphingomyelinase
neutral sphingomyelin phosphodiesterase activity (GO:0061751)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in a neutral environment.
Synonyms: neutral SMase; neutral sphingomyelinase
negative regulation of circulating fibrinogen levels (GO:0061754)
Namespace: biological_process
Definition: Any process that reduces the quantity of fibrinogen circulating in the bloodstream.
positive regulation of circulating fibrinogen levels (GO:0061755)
Namespace: biological_process
Definition: Any process that increases the quantity of fibrinogen circulating in the bloodstream.
leukocyte adhesion to vascular endothelial cell (GO:0061756)
Namespace: biological_process
Definition: The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.
leukocyte adhesion to arterial endothelial cell (GO:0061757)
Namespace: biological_process
Definition: The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.
obsolete (S)-2-hydroxyglutarate dehydrogenase activity, forward reaction (GO:0061758)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor => 2-oxoglutarate + reduced acceptor.
Synonyms: 2-hydroxyglutarate dehydrogenase activity, forward reaction; alpha-ketoglutarate reductase activity, reverse reaction
Comment: The reason for obsoletion is that this term is more specific than the specificity of any known gene product.
obsolete 2-oxoglutarate reductase activity (GO:0061759)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-oxoglutarate + reduced acceptor => (S)-2-hydroxyglutarate + acceptor.
Synonyms: 2-hydroxyglutarate dehydrogenase activity, reverse reaction; 2-ketoglutarate reductase activity; alpha-ketoglutarate reductase activity; D-2HG reductase activity
Comment: The reason for obsoletion is that this term is more specific than the specificity of any known gene product.
antifungal innate immune response (GO:0061760)
Namespace: biological_process
Definition: An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
alpha-latrotoxin receptor binding (GO:0061761)
Namespace: molecular_function
Definition: Binding to an alpha-latrotoxin receptor.
Synonyms: lasso receptor binding; latrophilin binding
multivesicular body-lysosome fusion (GO:0061763)
Namespace: biological_process
Definition: The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.
Synonyms: endosome-lysosome fusion; fusion of multivesicular body to lysosome; fusion of MVB to lysosome; late endosome-lysosome fusion; MVB-lysosome fusion
late endosome to lysosome transport via multivesicular body sorting pathway (GO:0061764)
Namespace: biological_process
Definition: The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
obsolete perturbation by virus of host non-canonical NF-kappaB signal transduction (GO:0061765)
Namespace: biological_process
Definition: OBSOLETE. A process in which a symbiont alters or subverts a non-canonical NF-kappaB signaling cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modulation by virus of host NIK/NF-kappaB cascade; modulation by virus of host NIK/NF-kappaB signaling; perturbation by virus of host NIK/NF-kappaB cascade
Comment: This term was obsoleted because it represents the same process as symbiont-mediated suppression of host NF-kappaB cascade ; GO:0085032.
positive regulation of lung blood pressure (GO:0061766)
Namespace: biological_process
Definition: The process that increases the force with which blood travels through the lungs.
Synonyms: positive regulation of pulmonary blood pressure
negative regulation of lung blood pressure (GO:0061767)
Namespace: biological_process
Definition: The process that decreases the force with which blood travels through the lungs.
Synonyms: negative regulation of pulmonary blood pressure