LiteFold/GO huggingface dataset:
effector-mediated defense to host-produced reactive oxygen species (GO:0033661)
Namespace: biological_process
Definition: A process mediated by a molecule secreted by a symbiont that results in the suppression of reactive oxygen species produced by the host as part of its innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: down regulation by organism of defense-related host metabolic burst; down-regulation by organism of defense-related host oxidative burst; downregulation by organism of defense-related host AOS production; negative regulation by organism of defense-related host reactive oxidative species production; negative regulation by organism of defense-related host reactive oxygen intermediate production; negative regulation by organism of defense-related host respiratory burst; negative regulation by organism of defense-related host ROI production; negative regulation by organism of defense-related host ROS production; negative regulation by symbiont of defense-related host reactive oxygen species production; suppression by symbiont of defense-related host reactive oxygen species production
obsolete positive regulation by symbiont of host defense-related protein level (GO:0033664)
Namespace: biological_process
Definition: OBSOLETE. Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because it is a readout, and annotations should be made to more informative terms.
obsolete regulation of growth or development of symbiont in host (GO:0033665)
Namespace: biological_process
Definition: OBSOLETE. Any process by which the symbiont regulates the increase in its size or mass, or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.
Synonyms: modulation of growth or development of organism within host; modulation of growth or development of symbiont within host; modulation of invasive growth; regulation of growth or development of symbiont in host; regulation of growth or development of symbiont within host
Comment: This term was made obsolete because it contained a conjunction (or).
obsolete positive regulation of growth or development of symbiont in host (GO:0033666)
Namespace: biological_process
Definition: OBSOLETE. Any process by which the symbiont activates, maintains or increases its size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
Synonyms: positive regulation of growth or development of symbiont in host; positive regulation of growth or development of symbiont within host; positive regulation of invasive growth; up regulation of growth or development of organism within host; up-regulation of growth or development of organism within host; upregulation of growth or development of organism within host
Comment: This term was made obsolete because it contained a conjunction (or).
obsolete negative regulation of growth or development of symbiont in host (GO:0033667)
Namespace: biological_process
Definition: OBSOLETE. Any process by which the symbiont stops, prevents or reduces its increase in size or mass or its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
Synonyms: down regulation of growth or development of organism within host; down-regulation of growth or development of organism within host; downregulation of growth or development of organism within host; inhibition of growth of development of organism within host; negative regulation of growth or development of symbiont in host; negative regulation of growth or development of symbiont within host; negative regulation of invasive growth
Comment: This term was made obsolete because it contained a conjunction (or).
symbiont-mediated suppression of host apoptosis (GO:0033668)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the normal execution of host apoptosis, leading to a decrease in the frequency, rate or extent of apoptosis in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: down regulation by organism of host apoptotic programmed cell death; down-regulation by organism of host apoptotic programmed cell death; downregulation by organism of host apoptotic programmed cell death; inhibition by organism of host apoptotic programmed cell death; negative regulation by symbiont of host apoptosis; negative regulation by symbiont of host apoptotic process; negative regulation by virus of host apoptosis; suppression by symbiont of host apoptotic process; suppression by virus of host apoptosis
Comment: Note that term is to be used to annotate gene products in the symbiont. To annotate host gene products, consider the biological process term 'negative regulation of apoptosis ; GO:0043066'.
obsolete regulation of NAD+ kinase activity (GO:0033670)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
Synonyms: NAD kinase regulator; regulation of NAD kinase activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of NAD+ kinase activity (GO:0033671)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
Synonyms: down regulation of NAD+ kinase activity; down-regulation of NAD+ kinase activity; downregulation of NAD+ kinase activity; inhibition of NAD+ kinase activity; NAD+ kinase inhibitor
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of NAD+ kinase activity (GO:0033672)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
Synonyms: NAD+ kinase activator; stimulation of NAD+ kinase activity; up regulation of NAD+ kinase activity; up-regulation of NAD+ kinase activity; upregulation of NAD+ kinase activity
Comment: This term was obsoleted because it represents a molecular function.
positive regulation of kinase activity (GO:0033674)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
Synonyms: kinase activator; stimulation of kinase activity; up regulation of kinase activity; up-regulation of kinase activity; upregulation of kinase activity
pericanalicular vesicle (GO:0033675)
Namespace: cellular_component
Definition: A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.
DNA/RNA helicase activity (GO:0033677)
Namespace: molecular_function
Definition: Unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA, driven by ATP hydrolysis.
Synonyms: ATP-dependent DNA/RNA helicase activity
5'-3' DNA/RNA helicase activity (GO:0033678)
Namespace: molecular_function
Definition: Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.
Synonyms: 5' to 3' DNA/RNA helicase activity; ATP-dependent 5' to 3' DNA/RNA helicase activity; ATP-dependent 5'-3' DNA/RNA helicase activity
3'-5' DNA/RNA helicase activity (GO:0033679)
Namespace: molecular_function
Definition: Unwinding of a DNA/RNA duplex in the 3' to 5' direction, driven by ATP hydrolysis.
Synonyms: 3' to 5' DNA/RNA helicase activity; ATP-dependent 3' to 5' DNA/RNA helicase activity; ATP-dependent 3'-5' DNA/RNA helicase activity
obsolete nucleotide-excision repair, DNA incision (GO:0033683)
Namespace: biological_process
Definition: OBSOLETE. A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.
Synonyms: DNA incision involved in nucleotide-excision repair; nucleic acid cleavage involved in nucleotide-excision repair
Comment: This term was obsoleted because it represents a molecular function.
regulation of luteinizing hormone secretion (GO:0033684)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.
negative regulation of luteinizing hormone secretion (GO:0033685)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.
Synonyms: down regulation of luteinizing hormone secretion; down-regulation of luteinizing hormone secretion; downregulation of luteinizing hormone secretion; inhibition of luteinizing hormone secretion
positive regulation of luteinizing hormone secretion (GO:0033686)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.
Synonyms: activation of luteinizing hormone secretion; stimulation of luteinizing hormone secretion; up regulation of luteinizing hormone secretion; up-regulation of luteinizing hormone secretion; upregulation of luteinizing hormone secretion
osteoblast proliferation (GO:0033687)
Namespace: biological_process
Definition: The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
regulation of osteoblast proliferation (GO:0033688)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of osteoblast proliferation.
negative regulation of osteoblast proliferation (GO:0033689)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.
Synonyms: down regulation of osteoblast proliferation; down-regulation of osteoblast proliferation; downregulation of osteoblast proliferation; inhibition of osteoblast proliferation
positive regulation of osteoblast proliferation (GO:0033690)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of osteoblast proliferation.
Synonyms: activation of osteoblast proliferation; stimulation of osteoblast proliferation; up regulation of osteoblast proliferation; up-regulation of osteoblast proliferation; upregulation of osteoblast proliferation
sialic acid binding (GO:0033691)
Namespace: molecular_function
Definition: Binding to a sialic acid, a N- or O- substituted derivative of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
Synonyms: N-acetylneuraminic acid binding
obsolete cellular polysaccharide biosynthetic process (GO:0033692)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.
Synonyms: cellular glycan biosynthesis; cellular glycan biosynthetic process; cellular polysaccharide anabolism; cellular polysaccharide biosynthesis; cellular polysaccharide formation; cellular polysaccharide synthesis
Comment: This term was obsoleted because it is not different from its parent, polysaccharide biosynthetic process ; GO:0000271.
neurofilament bundle assembly (GO:0033693)
Namespace: biological_process
Definition: The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.
Synonyms: NF bundle assembly
oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor (GO:0033694)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor (GO:0033695)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.
heterochromatin boundary formation (GO:0033696)
Namespace: biological_process
Definition: A process that forms a boundary that limits the spreading of heterochromatin along a chromosome.
Synonyms: maintenance of heterochromatin boundaries; negative regulation of extent of heterochromatin assembly; negative regulation of extent of heterochromatin formation; negative regulation of heterochromatin spreading; regulation of extent of heterochromatin assembly; regulation of extent of heterochromatin formation; regulation of heterochromatin spreading
obsolete positive regulation of extent of heterochromatin assembly (GO:0033697)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.
Synonyms: positive regulation of extent of heterochromatin formation; positive regulation of heterochromatin spreading
Comment: This term has been obsoleted because there is no evidence it exists.
Rpd3L complex (GO:0033698)
Namespace: cellular_component
Definition: A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors.
Synonyms: Clr6 histone deacetylase complex I/I'; Clr6L complex; Rpd3C(L); Sin3L complex
DNA 5'-adenosine monophosphate hydrolase activity (GO:0033699)
Namespace: molecular_function
Definition: Catalysis of the reactions: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H+; and: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O = a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H+. Nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.
Synonyms: AMP-removal activity; DNA 5'-adenylate hydrolase activity; DNA adenylate hydrolysis activity; DNA de-adenylation; DNA deadenylation
phospholipid efflux (GO:0033700)
Namespace: biological_process
Definition: The directed movement of a phospholipid out of a cell or organelle.
Synonyms: phospholipid export
dTDP-galactose 6-dehydrogenase activity (GO:0033701)
Namespace: molecular_function
Definition: Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.
Synonyms: dTDP-D-galactose:NADP+ 6-oxidoreductase activity; dTDPgalactose 6-dehydrogenase activity; thymidine-diphosphate-galactose dehydrogenase activity
(+)-trans-carveol dehydrogenase activity (GO:0033702)
Namespace: molecular_function
Definition: Catalysis of the reaction: (1R,5S)-carveol + NAD+ = (S)-carvone + H+ + NADH.
Synonyms: (+)-trans-carveol:NAD+ oxidoreductase activity
3-beta-hydroxy-5-beta-steroid dehydrogenase (NADP+) activity (GO:0033703)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-beta-hydroxy-5-beta-pregnane-20-one + NADP+ = 5-beta-pregnan-3,20-dione + H+ + NADPH.
Synonyms: 3beta-hydroxy-5beta-steroid:NADP+ 3-oxidoreductase activity; 3beta-hydroxysteroid 5beta-oxidoreductase activity; 3beta-hydroxysteroid 5beta-progesterone oxidoreductase activity
3-beta-hydroxy-5-alpha-steroid dehydrogenase (NADP+) activity (GO:0033704)
Namespace: molecular_function
Definition: Catalysis of the reaction: -3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5-alpha-pregnane-3,20-dione + H+ + NADPH.
Synonyms: 3beta-hydroxy-5alpha-steroid:NADP+ 3-oxidoreductase activity
3''-deamino-3''-oxonicotianamine reductase activity (GO:0033707)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.
Synonyms: 2'-deoxymugineic acid:NAD(P)+ 3''-oxidoreductase activity
D-arabinitol dehydrogenase (NADP+) activity (GO:0033709)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+. Can also produce D-ribulose.
Synonyms: ARD1p; D-arabinitol dehydrogenase 1 activity; D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity; D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity; D-arabinitol:NADP+ dehydrogenase activity; NADP+-dependent D-arabinitol dehydrogenase activity
4-phosphoerythronate dehydrogenase activity (GO:0033711)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4-phospho-D-erythronate + NAD+ = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H+ + NADH.
Synonyms: 4-O-phosphoerythronate dehydrogenase activity; 4-phospho-D-erythronate:NAD+ 2-oxidoreductase activity; 4PE dehydrogenase activity; erythronate-4-phosphate dehydrogenase activity; PdxB; PdxB 4PE dehydrogenase activity
1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity (GO:0033712)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP+ = 1,5-anhydro-D-fructose + H+ + NADPH.
Synonyms: 1,5-anhydro-D-mannitol:NADP+ oxidoreductase activity; AFR
choline:oxygen 1-oxidoreductase activity (GO:0033713)
Namespace: molecular_function
Definition: Catalysis of the reaction: choline + O2 = betaine aldehyde + H2O2.
Synonyms: choline oxidase activity
secondary-alcohol oxidase activity (GO:0033714)
Namespace: molecular_function
Definition: Catalysis of the reaction: secondary alcohol + O2 = H2O2 + ketone.
Synonyms: polyvinyl alcohol oxidase activity; secondary alcohol oxidase activity; secondary-alcohol:oxygen oxidoreductase activity
nucleoside oxidase activity (GO:0033715)
Namespace: molecular_function
Definition: Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.
Synonyms: nucleoside:oxygen 5'-oxidoreductase activity
gluconate 2-dehydrogenase (acceptor) activity (GO:0033717)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.
Synonyms: 2-ketogluconate reductase activity; D-gluconate dehydrogenase activity; D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding activity; D-gluconate:(acceptor) 2-oxidoreductase activity; D-gluconate:acceptor 2-oxidoreductase activity; gluconate oxidase activity; gluconic acid dehydrogenase activity; gluconic dehydrogenase activity
pyranose dehydrogenase (acceptor) activity (GO:0033718)
Namespace: molecular_function
Definition: Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.
Synonyms: PDH; pyranose dehydrogenase activity; pyranose-quinone oxidoreductase activity; pyranose:acceptor oxidoreductase activity; quinone-dependent pyranose dehydrogenase activity
(2R)-oxo-acid reductase activity (GO:0033719)
Namespace: molecular_function
Definition: Catalysis of the reaction: a (2R)-hydroxycarboxylate + acceptor = a 2-oxocarboxylate + reduced acceptor.
Synonyms: (2R)-hydroxy-carboxylate:acceptor oxidoreductase activity; (2R)-hydroxycarboxylate-viologen-oxidoreductase activity; 2-oxo-acid reductase activity; 2-oxoacid reductase activity; HVOR
(S)-mandelate dehydrogenase activity (GO:0033720)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.
Synonyms: (S)-2-hydroxy-2-phenylacetate:acceptor 2-oxidoreductase activity; L(+)-mandelate dehydrogenase activity; MDH
aldehyde dehydrogenase (NADP+) activity (GO:0033721)
Namespace: molecular_function
Definition: Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
Synonyms: aldehyde:NADP+ oxidoreductase activity; NADP-acetaldehyde dehydrogenase activity; NADP-dependent aldehyde dehydrogenase activity
fluoroacetaldehyde dehydrogenase (NAD+) activity (GO:0033723)
Namespace: molecular_function
Definition: Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.
Synonyms: fluoroacetaldehyde:NAD+ oxidoreductase activity
aldehyde ferredoxin oxidoreductase activity (GO:0033726)
Namespace: molecular_function
Definition: Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.
Synonyms: aldehyde:ferredoxin oxidoreductase activity; AOR; tungsten-containing aldehyde ferredoxin oxidoreductase activity
3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activity (GO:0033728)
Namespace: molecular_function
Definition: Catalysis of the reaction: protochlorophyllide a + NADP+ = 3,8-divinyl protochlorophyllide a + NADPH + H+, and chlorophyllide a + NADP+ = 3,8-divinyl chlorophyllide a + NADPH + H+.
Synonyms: 3,8-divinyl protochlorophyllide a 8-vinyl reductase activity; 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activit; 4VCR; [4-vinyl]chlorophyllide a reductase activity; chlorophyllide-a:NADP+ oxidoreductase activity
arogenate dehydrogenase (NADP+) activity (GO:0033730)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.
Synonyms: arogenic dehydrogenase activity; L-arogenate:NADP+ oxidoreductase (decarboxylating) activity; pretyrosine dehydrogenase activity; TyrAa; TyrAAT1; TyrAAT2
pyrroloquinoline-quinone synthase activity (GO:0033732)
Namespace: molecular_function
Definition: Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = 2 H2O + 2 H2O2 + H+ + pyrroloquinoline quinone.
Synonyms: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,5,6,7,8-octahydroquinoline-2,4-dicarboxylate:oxygen oxidoreductase (cyclizing) activity; PqqC
(R)-benzylsuccinyl-CoA dehydrogenase activity (GO:0033734)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.
Synonyms: (R)-benzylsuccinyl-CoA:(acceptor) oxidoreductase activity; (R)-benzylsuccinyl-CoA:acceptor oxidoreductase activity; BbsG