LiteFold/GO huggingface dataset:
obsolete positive regulation of prostaglandin-endoperoxide synthase activity (GO:0060585)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
Synonyms: positive regulation of (PG)H synthase activity; positive regulation of fatty acid cyclooxygenase activity; positive regulation of PG synthetase activity; positive regulation of prostaglandin synthetase activity
Comment: This term was obsoleted because it represents a molecular function.
multicellular organismal-level iron ion homeostasis (GO:0060586)
Namespace: biological_process
Definition: A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms: multicellular organismal iron ion homeostasis
regulation of lipoprotein lipid oxidation (GO:0060587)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.
nucleoside-triphosphatase regulator activity (GO:0060589)
Namespace: molecular_function
Definition: Binds to and modulates the activity of an NTPase.
Synonyms: NTPase regulator activity
ATPase regulator activity (GO:0060590)
Namespace: molecular_function
Definition: Binds to and modulates the activity of an ATP hydrolysis activity.
Synonyms: ATP hydrolysis regulator activity
chondroblast differentiation (GO:0060591)
Namespace: biological_process
Definition: The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.
Synonyms: chondrocyte progenitor cell differentiation
mammary gland formation (GO:0060592)
Namespace: biological_process
Definition: The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.
Synonyms: mammary bud formation; mammary line formation; mammary placode formation; mammary sprout formation
obsolete Wnt signaling pathway involved in mammary gland specification (GO:0060593)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
Synonyms: Wnt receptor signaling pathway involved in mammary gland specification; Wnt receptor signalling pathway involved in mammary gland specification; Wnt-activated signaling pathway involved in mammary gland specification
Comment: This term was obsoleted because it represents a GO-CAM model.
fibroblast growth factor receptor signaling pathway involved in mammary gland specification (GO:0060595)
Namespace: biological_process
Definition: The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
Synonyms: fibroblast growth factor receptor signalling pathway involved in mammary gland specification
mammary placode formation (GO:0060596)
Namespace: biological_process
Definition: The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.
obsolete regulation of transcription from RNA polymerase II promoter involved in mammary gland formation (GO:0060597)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud.
Comment: This term was obsoleted because it represents a GO-CAM model.
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis (GO:0060598)
Namespace: biological_process
Definition: The process in which the terminal end of a mammary duct bifurcates.
Synonyms: primary mammary duct branching
lateral sprouting involved in mammary gland duct morphogenesis (GO:0060599)
Namespace: biological_process
Definition: The process in which a branch forms along the side of a mammary duct.
Synonyms: mammary gland duct secondary branching
dichotomous subdivision of an epithelial terminal unit (GO:0060600)
Namespace: biological_process
Definition: The process in which an epithelial cord, rod or tube bifurcates at its end.
Synonyms: primary branching of an epithelium
lateral sprouting from an epithelium (GO:0060601)
Namespace: biological_process
Definition: The process in which a branch forms along the side of an epithelium.
branch elongation of an epithelium (GO:0060602)
Namespace: biological_process
Definition: The growth process in which a branch increases in length from its base to its tip.
mammary gland duct morphogenesis (GO:0060603)
Namespace: biological_process
Definition: The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
mammary gland duct cavitation (GO:0060604)
Namespace: biological_process
Definition: Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.
Synonyms: milk duct cavitation
tube lumen cavitation (GO:0060605)
Namespace: biological_process
Definition: The formation of a lumen by hollowing out a solid rod or cord.
tube closure (GO:0060606)
Namespace: biological_process
Definition: Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.
obsolete cell-cell adhesion involved in sealing an epithelial fold (GO:0060607)
Namespace: biological_process
Definition: OBSOLETE. The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete cell-cell adhesion involved in neural tube closure (GO:0060608)
Namespace: biological_process
Definition: OBSOLETE. The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete apoptotic process involved in tube lumen cavitation (GO:0060609)
Namespace: biological_process
Definition: OBSOLETE. Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.
Synonyms: apoptosis involved in tube lumen cavitation
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mammary gland fat development (GO:0060611)
Namespace: biological_process
Definition: The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.
adipose tissue development (GO:0060612)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.
Synonyms: adipogenesis
fat pad development (GO:0060613)
Namespace: biological_process
Definition: The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.
obsolete negative regulation of mammary gland development in males by androgen receptor signaling pathway (GO:0060614)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.
Synonyms: negative regulation of mammary gland development in males by androgen receptor signalling pathway
Comment: This term was obsoleted because it is a pre-composed term that represents a GO-CAM model
mammary gland bud formation (GO:0060615)
Namespace: biological_process
Definition: The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.
mammary gland cord formation (GO:0060616)
Namespace: biological_process
Definition: The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.
Synonyms: mammary gland sprout formation
nipple development (GO:0060618)
Namespace: biological_process
Definition: The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.
obsolete cell migration involved in mammary placode formation (GO:0060619)
Namespace: biological_process
Definition: OBSOLETE. The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of cholesterol import (GO:0060620)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.
regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process (GO:0060624)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.
Synonyms: regulation of ascospore wall 1,3-beta-D-glucan biosynthetic process; regulation of ascospore wall 1,3-beta-glucan biosynthetic process
regulation of protein deneddylation (GO:0060625)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.
Synonyms: regulation of cullin deneddylation
regulation of vesicle-mediated transport (GO:0060627)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
regulation of ER to Golgi vesicle-mediated transport (GO:0060628)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
regulation of homologous chromosome segregation (GO:0060629)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
obsolete regulation of M/G1 transition of mitotic cell cycle (GO:0060630)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency, or extent of M/G1 transition of the mitotic cell cycle, the progression from M phase to G1 phase of the mitotic cell cycle.
Synonyms: regulation of M/G1 transition of mitotic cell cycle
Comment: This term was made obsolete because it does not refer to a real biological process.
regulation of microtubule-based movement (GO:0060632)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
negative regulation of transcription initiation by RNA polymerase II (GO:0060633)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
Synonyms: negative regulation of transcription initiation from RNA polymerase II promoter
regulation of 4,6-pyruvylated galactose residue biosynthetic process (GO:0060634)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.
positive regulation of (1->3)-beta-D-glucan biosynthetic process (GO:0060635)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
Synonyms: positive regulation of 1,3-beta-D-glucan biosynthetic process
positive regulation of lactation by mesenchymal-epithelial cell signaling (GO:0060637)
Namespace: biological_process
Definition: The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.
Synonyms: positive regulation of lactation by mesenchymal-epithelial cell signalling
mesenchymal-epithelial cell signaling (GO:0060638)
Namespace: biological_process
Definition: Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.
Synonyms: mesenchymal-epithelial cell signalling
positive regulation of salivary gland formation by mesenchymal-epithelial signaling (GO:0060639)
Namespace: biological_process
Definition: Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.
Synonyms: positive regulation of salivary gland formation by mesenchymal-epithelial signalling
positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling (GO:0060640)
Namespace: biological_process
Definition: Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.
Synonyms: positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signaling; positive regulation of dentine-containing tooth bud formation by mesenchymal-epithelial signalling
mammary gland duct regression in males (GO:0060641)
Namespace: biological_process
Definition: The process in which the epithelium of the mammary duct is destroyed in males.
obsolete white fat cell differentiation involved in mammary gland fat development (GO:0060642)
Namespace: biological_process
Definition: OBSOLETE. The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mammary gland epithelial cell differentiation (GO:0060644)
Namespace: biological_process
Definition: The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.
peripheral mammary gland bud epithelial cell differentiation (GO:0060645)
Namespace: biological_process
Definition: The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.
internal mammary gland bud epithelial cell differentiation (GO:0060646)
Namespace: biological_process
Definition: The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.
obsolete mesenchymal cell condensation involved in mammary fat development (GO:0060647)
Namespace: biological_process
Definition: OBSOLETE. The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mammary gland bud morphogenesis (GO:0060648)
Namespace: biological_process
Definition: The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.
mammary gland bud elongation (GO:0060649)
Namespace: biological_process
Definition: The process in which the mammary gland bud grows along its axis.
obsolete epithelial cell proliferation involved in mammary gland bud elongation (GO:0060650)
Namespace: biological_process
Definition: OBSOLETE. The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete regulation of epithelial cell proliferation involved in mammary gland bud elongation (GO:0060651)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mammary gland cord morphogenesis (GO:0060652)
Namespace: biological_process
Definition: The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.
Synonyms: mammary gland sprout morphogenesis
obsolete epithelial cell differentiation involved in mammary gland cord morphogenesis (GO:0060653)
Namespace: biological_process
Definition: OBSOLETE. The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.
Synonyms: epithelial cell differentiation involved in mammary gland sprout morphogenesis
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mammary gland cord elongation (GO:0060654)
Namespace: biological_process
Definition: The process in which the mammary gland sprout grows along its axis.
obsolete branching involved in mammary gland cord morphogenesis (GO:0060655)
Namespace: biological_process
Definition: OBSOLETE. The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling (GO:0060656)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.
Synonyms: regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signalling
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling (GO:0060657)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.
Synonyms: regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signalling
nipple morphogenesis (GO:0060658)
Namespace: biological_process
Definition: The process in which the nipple is generated and organized.
nipple sheath formation (GO:0060659)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.
obsolete epidermis morphogenesis involved in nipple formation (GO:0060660)
Namespace: biological_process
Definition: OBSOLETE. The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
submandibular salivary gland formation (GO:0060661)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.
salivary gland cavitation (GO:0060662)
Namespace: biological_process
Definition: The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.
Synonyms: salivary gland invagination
obsolete apoptotic process involved in salivary gland cavitation (GO:0060663)
Namespace: biological_process
Definition: OBSOLETE. Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.
Synonyms: apoptosis involved in salivary gland cavitation
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
epithelial cell proliferation involved in salivary gland morphogenesis (GO:0060664)
Namespace: biological_process
Definition: The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.