LiteFold/GO huggingface dataset:
cuticle development involved in chitin-based cuticle molting cycle (GO:0042337)
Namespace: biological_process
Definition: The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.
Synonyms: chitin-based cuticle development during molting; cuticle anabolism during molting; cuticle biosynthetic process during molting; cuticle formation during molting; cuticle synthesis during molting
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
cuticle development involved in collagen and cuticulin-based cuticle molting cycle (GO:0042338)
Namespace: biological_process
Definition: Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.
Synonyms: collagen and cuticulin-based cuticle development during molting; cuticle anabolism during molting; cuticle biosynthetic process during molting; cuticle formation during molting; cuticle synthesis during molting
keratan sulfate proteoglycan metabolic process (GO:0042339)
Namespace: biological_process
Definition: The chemical reactions and pathways involving keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated.
Synonyms: keratan sulfate metabolism; keratan sulphate metabolic process; keratan sulphate metabolism
keratan sulfate proteoglycan catabolic process (GO:0042340)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of keratan sulfate proteoglycans, which consist of a core protein linked to a keratan sulfate glycosaminoglycan. The keratan sulfate chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-beta-(1,3)-galactose, both of which can be sulfated.
Synonyms: keratan sulfate breakdown; keratan sulfate catabolism; keratan sulfate degradation; keratan sulphate catabolic process; keratan sulphate catabolism
obsolete cyanogenic glycoside metabolic process (GO:0042341)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
Synonyms: cyanogenic glycoside metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
indole glucosinolate metabolic process (GO:0042343)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.
Synonyms: indole glucosinolate metabolism
indole glucosinolate catabolic process (GO:0042344)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
Synonyms: indole glucosinolate breakdown; indole glucosinolate catabolism; indole glucosinolate degradation
guiding stereospecific synthesis activity (GO:0042349)
Namespace: molecular_function
Definition: The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.
Synonyms: dirigent protein
GDP-L-fucose biosynthetic process (GO:0042350)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
Synonyms: GDP-L-fucose anabolism; GDP-L-fucose biosynthesis; GDP-L-fucose formation; GDP-L-fucose synthesis
'de novo' GDP-L-fucose biosynthetic process (GO:0042351)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
Synonyms: 'de novo' GDP-L-fucose anabolism; 'de novo' GDP-L-fucose biosynthesis; 'de novo' GDP-L-fucose formation; 'de novo' GDP-L-fucose synthesis; GDP-L-fucose biosynthesis, de novo pathway; GDP-L-fucose biosynthetic process, de novo pathway
GDP-L-fucose salvage (GO:0042352)
Namespace: biological_process
Definition: The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).
Synonyms: GDP-L-fucose biosynthesis, salvage pathway; GDP-L-fucose biosynthetic process, salvage pathway
fucose biosynthetic process (GO:0042353)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).
Synonyms: fucose anabolism; fucose biosynthesis; fucose formation; fucose synthesis
L-fucose metabolic process (GO:0042354)
Namespace: biological_process
Definition: The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.
Synonyms: L-fucose metabolism
L-fucose catabolic process (GO:0042355)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
Synonyms: L-fucose breakdown; L-fucose catabolism; L-fucose degradation
GDP-4-dehydro-D-rhamnose reductase activity (GO:0042356)
Namespace: molecular_function
Definition: Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
Synonyms: GDP-4-keto-6-deoxy-D-mannose reductase activity; GDP-4-keto-D-rhamnose reductase activity; GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase activity; guanosine diphosphate-4-keto-D-rhamnose reductase activity
thiamine diphosphate metabolic process (GO:0042357)
Namespace: biological_process
Definition: The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
Synonyms: thiamin diphosphate metabolic process; thiamin diphosphate metabolism; thiamin pyrophosphate metabolic process; thiamin pyrophosphate metabolism; thiamine diphosphate metabolism; thiamine pyrophosphate metabolic process; thiamine pyrophosphate metabolism; TPP metabolic process; TPP metabolism
vitamin D metabolic process (GO:0042359)
Namespace: biological_process
Definition: The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms: calciferol metabolic process; calciferol metabolism; cholecalciferol metabolic process; cholecalciferol metabolism; ergocalciferol metabolic process; ergocalciferol metabolism; vitamin D metabolism
vitamin E metabolic process (GO:0042360)
Namespace: biological_process
Definition: The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
Synonyms: alpha-tocopherol metabolic process; alpha-tocopherol metabolism; tocopherol metabolic process; tocopherol metabolism; vitamin E metabolism
menaquinone catabolic process (GO:0042361)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
Synonyms: menaquinone breakdown; menaquinone catabolism; menaquinone degradation; menatetrenone catabolic process; menatetrenone catabolism; multiprenylmenaquinone catabolic process; multiprenylmenaquinone catabolism; vitamin K2 catabolic process; vitamin K2 catabolism
fat-soluble vitamin biosynthetic process (GO:0042362)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms: fat-soluble vitamin anabolism; fat-soluble vitamin biosynthesis; fat-soluble vitamin formation; fat-soluble vitamin synthesis
fat-soluble vitamin catabolic process (GO:0042363)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms: fat-soluble vitamin breakdown; fat-soluble vitamin catabolism; fat-soluble vitamin degradation
water-soluble vitamin biosynthetic process (GO:0042364)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.
Synonyms: water-soluble vitamin anabolism; water-soluble vitamin biosynthesis; water-soluble vitamin formation; water-soluble vitamin synthesis
cobalamin catabolic process (GO:0042366)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
Synonyms: cobalamin breakdown; cobalamin catabolism; cobalamin degradation; vitamin B12 catabolic process; vitamin B12 catabolism
biotin catabolic process (GO:0042367)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
Synonyms: biotin breakdown; biotin catabolism; biotin degradation; vitamin B7 catabolic process; vitamin B7 catabolism; vitamin H catabolic process; vitamin H catabolism
vitamin D biosynthetic process (GO:0042368)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms: calciferol biosynthesis; calciferol biosynthetic process; cholecalciferol biosynthesis; cholecalciferol biosynthetic process; ergocalciferol biosynthesis; ergocalciferol biosynthetic process; vitamin D anabolism; vitamin D biosynthesis; vitamin D formation; vitamin D synthesis
vitamin D catabolic process (GO:0042369)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms: calciferol catabolic process; calciferol catabolism; cholecalciferol biosynthesis; cholecalciferol biosynthetic process; ergocalciferol biosynthesis; ergocalciferol biosynthetic process; vitamin D breakdown; vitamin D catabolism; vitamin D degradation
thiamine diphosphate dephosphorylation (GO:0042370)
Namespace: biological_process
Definition: The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
Synonyms: thiamin diphosphate dephosphorylation; TPP dephosphorylation
vitamin K biosynthetic process (GO:0042371)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
Synonyms: naphthoquinone metabolic process; naphthoquinone metabolism; vitamin K anabolism; vitamin K biosynthesis; vitamin K formation; vitamin K synthesis
phylloquinone biosynthetic process (GO:0042372)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
Synonyms: phylloquinone anabolism; phylloquinone biosynthesis; phylloquinone formation; phylloquinone synthesis; phytomenadione biosynthesis; phytomenadione biosynthetic process; phytonadione biosynthesis; phytonadione biosynthetic process; phytylmenaquinone biosynthesis; phytylmenaquinone biosynthetic process; vitamin K1 biosynthesis; vitamin K1 biosynthetic process
vitamin K metabolic process (GO:0042373)
Namespace: biological_process
Definition: The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
Synonyms: naphthoquinone metabolic process; naphthoquinone metabolism; vitamin K metabolism
obsolete phylloquinone metabolic process (GO:0042374)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.
Synonyms: phylloquinone metabolism; phytomenadione metabolic process; phytomenadione metabolism; phytonadione metabolic process; phytonadione metabolism; phytylmenaquinone metabolic process; phytylmenaquinone metabolism; vitamin K1 metabolic process; vitamin K1 metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
phylloquinone catabolic process (GO:0042376)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
Synonyms: phylloquinone breakdown; phylloquinone catabolism; phylloquinone degradation; phytomenadione catabolic process; phytomenadione catabolism; phytonadione catabolic process; phytonadione catabolism; phytylmenaquinone catabolic process; phytylmenaquinone catabolism; vitamin K1 catabolic process; vitamin K1 catabolism
vitamin K catabolic process (GO:0042377)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
Synonyms: naphthoquinone catabolic process; naphthoquinone catabolism; vitamin K breakdown; vitamin K catabolism; vitamin K degradation
chemokine receptor binding (GO:0042379)
Namespace: molecular_function
Definition: Binding to a chemokine receptor.
Synonyms: chemokine receptor ligand
obsolete hydroxymethylbutenyl pyrophosphate reductase activity (GO:0042380)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
Synonyms: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming)
Comment: The reason for obsoletion is that this term is equivalent to 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity.
sarcolemma (GO:0042383)
Namespace: cellular_component
Definition: The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
myosin III complex (GO:0042385)
Namespace: cellular_component
Definition: A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.
plasmatocyte differentiation (GO:0042387)
Namespace: biological_process
Definition: The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.
gibberellic acid mediated signaling pathway, G-alpha-dependent (GO:0042388)
Namespace: biological_process
Definition: The series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
Synonyms: gibberellic acid mediated signalling, G-alpha-dependent
omega-3 fatty acid desaturase activity (GO:0042389)
Namespace: molecular_function
Definition: Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.
gibberellic acid mediated signaling pathway, G-alpha-independent (GO:0042390)
Namespace: biological_process
Definition: The series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
Synonyms: gibberellic acid mediated signalling, G-alpha-independent
regulation of membrane potential (GO:0042391)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
sphingosine-1-phosphate phosphatase activity (GO:0042392)
Namespace: molecular_function
Definition: Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.
Synonyms: sphingosine-1-phosphate phosphohydrolase activity; SPP phosphatase activity; SPPase activity
histone binding (GO:0042393)
Namespace: molecular_function
Definition: Binding to a histone, any of a group of water-soluble proteins found in association with the DNA of eukaryotic or archaeal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in gene regulation and DNA replication. They may be chemically modified (methylated, acetlyated and others) to regulate gene transcription.
Synonyms: histone-specific chaperone activity
obsolete ecdysis, protein-based cuticle (GO:0042394)
Namespace: biological_process
Definition: OBSOLETE. The shedding of the old protein-based cuticular fragments during the molting cycle. Examples of this process are found in invertebrates.
Synonyms: ecdysis, protein-based cuticle
Comment: This term was made obsolete because 'protein-based cuticle' is an unnecessary grouping term.
ecdysis, collagen and cuticulin-based cuticle (GO:0042395)
Namespace: biological_process
Definition: The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.
phosphagen biosynthetic process (GO:0042396)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
Synonyms: phosphagen anabolism; phosphagen biosynthesis; phosphagen formation; phosphagen synthesis
phosphagen catabolic process (GO:0042397)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
Synonyms: phosphagen breakdown; phosphagen catabolism; phosphagen degradation
modified amino acid biosynthetic process (GO:0042398)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
Synonyms: amino acid derivative biosynthetic process; cellular amino acid derivative anabolism; cellular amino acid derivative biosynthesis; cellular amino acid derivative biosynthetic process; cellular amino acid derivative formation; cellular amino acid derivative synthesis; cellular modified amino acid anabolism; cellular modified amino acid biosynthesis; cellular modified amino acid formation; cellular modified amino acid synthesis
obsolete ectoine metabolic process (GO:0042399)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
Synonyms: ectoine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
ectoine catabolic process (GO:0042400)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
Synonyms: ectoine breakdown; ectoine catabolism; ectoine degradation
biogenic amine catabolic process (GO:0042402)
Namespace: biological_process
Definition: The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
Synonyms: biogenic amine breakdown; biogenic amine catabolism; biogenic amine degradation
thyroid hormone catabolic process (GO:0042404)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
Synonyms: thyroid hormone breakdown; thyroid hormone catabolism; thyroid hormone degradation
nuclear inclusion body (GO:0042405)
Namespace: cellular_component
Definition: An intranuclear focus at which aggregated proteins have been sequestered.
extrinsic component of endoplasmic reticulum membrane (GO:0042406)
Namespace: cellular_component
Definition: The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
Synonyms: extrinsic to endoplasmic reticulum membrane; extrinsic to ER membrane
cristae formation (GO:0042407)
Namespace: biological_process
Definition: The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
obsolete myrcene/(E)-beta-ocimene synthase activity (GO:0042408)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the conversion of geranyl diphosphate (GPP) into the acyclic monoterpenes beta-myrcene, (E)-beta-ocimene, and other minor cyclic monoterpenes.
Synonyms: myrcene/(E)-beta-ocimene synthase activity; myrcene/ocimene synthase activity
Comment: This term was made obsolete because it represents two activities.