LiteFold/GO huggingface dataset:
glutathione-dependent sulfide quinone oxidoreductase activity (GO:0106436)
Namespace: molecular_function
Definition: Catalysis of the reaction: a quinone + glutathione + H+ + hydrogen sulfide = a quinol + S-sulfanylglutathione.
Synonyms: eukaryotic sulfide quinone oxidoreductase
protein-glutamic acid ligase activity, initiating (GO:0106437)
Namespace: molecular_function
Definition: Catalytic reaction: ATP + L-glutamate + L-glutamyl-[protein] = ADP + H+ + L-gamma-glutamyl-L-glutamyl-[protein] + phosphate.
protein-glutamic acid ligase activity, elongating (GO:0106438)
Namespace: molecular_function
Definition: Catalytic reaction :(L-glutamyl)n-L-gamma-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate = (L-glutamyl)n+1-L-gamma-glutamyl-L-glutamyl-[protein] + ADP + H+ + phosphate.
L-lysine:L-arginine antiporter activity (GO:0106439)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out).
Comment: L-arginine:L-lysine antiporter activity
toxin-antitoxin complex (GO:0110001)
Namespace: cellular_component
Definition: A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.
Comment: An example is YoeB (P69348) in Escherichia coli in PMID:16109374 (inferred by direct evidence).
regulation of tRNA methylation (GO:0110002)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.
regulation of tRNA C5-cytosine methylation (GO:0110003)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA C5-cytosine methylation.
positive regulation of tRNA methylation (GO:0110004)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of tRNA methylation.
positive regulation of tRNA C5-cytosine methylation (GO:0110005)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of tRNA C5-cytosine methylation.
formin-nucleated actin cable organization (GO:0110009)
Namespace: biological_process
Definition: A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.
basolateral protein secretion (GO:0110010)
Namespace: biological_process
Definition: The controlled release of proteins from a cell at the sides which interface adjacent cells and near the base.
regulation of basement membrane organization (GO:0110011)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane.
protein localization to P-body (GO:0110012)
Namespace: biological_process
Definition: Any process in which a protein is transported to, or maintained at, a P-body.
Synonyms: protein localisation to P-body; protein localization to cytoplasmic mRNA processing body; protein localization to P body
positive regulation of aggregation involved in sorocarp development (GO:0110013)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
negative regulation of aggregation involved in sorocarp development (GO:0110014)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of aggregation involved in sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
B-WICH complex (GO:0110016)
Namespace: cellular_component
Definition: A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. Located in the nucleolus where it assembles on RNA Polymerase I (Pol I) and possibly on RNA Polymerase III (Pol III) promoter and coding regions during early G1 phase and activates the post-initiation phases of Pol I transcription. May also activate RNA Polymerase II (Pol II) gene transcription. In mammals, B-WICH contains the WICH complex core of BAZ1B and SMARCA5, additional protein subunits and possibly rRNAs. Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself.
Comment: An example is BAZ1B (Q9UIG0) in human in PMID:16603771 (by IPI).
cap-independent translational initiation of circular RNA (GO:0110018)
Namespace: biological_process
Definition: The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.
Synonyms: cap-independent translational initiation of circRNA
IRES-dependent translational initiation of circular RNA (GO:0110019)
Namespace: biological_process
Definition: The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.
Synonyms: IRES-dependent translational initiation of circRNA
regulation of actomyosin structure organization (GO:0110020)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin.
cardiac muscle myoblast proliferation (GO:0110021)
Namespace: biological_process
Definition: The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
regulation of cardiac muscle myoblast proliferation (GO:0110022)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.
negative regulation of cardiac muscle myoblast proliferation (GO:0110023)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation.
positive regulation of cardiac muscle myoblast proliferation (GO:0110024)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.
regulation of DNA strand resection involved in replication fork processing (GO:0110026)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.
negative regulation of DNA strand resection involved in replication fork processing (GO:0110027)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of DNA strand resection involved in replication fork processing.
positive regulation of mitotic spindle organization (GO:0110028)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of mitotic spindle organization.
negative regulation of meiosis I (GO:0110029)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
regulation of G2/MI transition of meiotic cell cycle (GO:0110030)
Namespace: biological_process
Definition: Any signaling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
negative regulation of G2/MI transition of meiotic cell cycle (GO:0110031)
Namespace: biological_process
Definition: Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
positive regulation of G2/MI transition of meiotic cell cycle (GO:0110032)
Namespace: biological_process
Definition: Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to MI phase of the meiotic cell cycle.
regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway (GO:0110033)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway, the series of molecular signals generated as a consequence of glucose binding to a G protein-coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
Synonyms: regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway
negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway (GO:0110034)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.
Synonyms: negative regulation of adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway
obsolete rDNA spacer replication fork barrier binding, bending (GO:0110035)
Namespace: molecular_function
Definition: OBSOLETE. The activity of binding selectively, and in a sequence-specific manner, a replication fork barrier found in rDNA spacers, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
Comment: This term was obsoleted because it is precomposed.
C2 domain binding (GO:0110036)
Namespace: molecular_function
Definition: Binding to the C2 domain of a protein, a protein structural domain involved in targeting proteins to cell membranes.
regulation of nematode male tail tip morphogenesis (GO:0110037)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of nematode male tail tip morphogenesis, the process in which the anatomical structure of the adult male tail tip is generated and organized.
negative regulation of nematode male tail tip morphogenesis (GO:0110038)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.
positive regulation of nematode male tail tip morphogenesis (GO:0110039)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of nematode male tail tip morphogenesis.
nematode pharynx morphogenesis (GO:0110040)
Namespace: biological_process
Definition: The process in which the anatomical structures of the nematode pharynx are generated and organized.
negative regulation of nematode pharynx morphogenesis (GO:0110042)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of nematode pharynx morphogenesis.
regulation of cell cycle switching, mitotic to meiotic cell cycle (GO:0110044)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
Synonyms: sexual differentiation
negative regulation of cell cycle switching, mitotic to meiotic cell cycle (GO:0110045)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of mitotic to meiotic cell cycle switching, the process in which a cell switches cell cycle mode from mitotic to meiotic division.
deaminated glutathione amidase activity (GO:0110050)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.
Comment: N-(4-oxoglutarate)-L-cysteinylglycine = deaminated glutathione
metabolite repair (GO:0110051)
Namespace: biological_process
Definition: A cellular process that, through single- or multi-step enzymatic reactions, repairs useless or toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
toxic metabolite repair (GO:0110052)
Namespace: biological_process
Definition: A cellular process that, through single- or multi-step enzymatic reactions, repairs toxic endogenous compounds, formed as by-products of primary metabolism, by converting them into useful metabolites.
regulation of actin filament organization (GO:0110053)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of actin filament organization.
regulation of actin filament annealing (GO:0110054)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
negative regulation of actin filament annealing (GO:0110055)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
regulation of blood vessel endothelial cell differentiation (GO:0110057)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.
positive regulation of blood vessel endothelial cell differentiation (GO:0110058)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation.
negative regulation of blood vessel endothelial cell differentiation (GO:0110059)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation.
regulation of angiotensin-activated signaling pathway (GO:0110061)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.
negative regulation of angiotensin-activated signaling pathway (GO:0110062)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the angiotensin-activated signaling pathway.
positive regulation of angiotensin-activated signaling pathway (GO:0110063)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.
lncRNA catabolic process (GO:0110064)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lncRNAs, non-coding RNAs over 200 nucleotides in length.
Synonyms: lncRNA breakdown; lncRNA catabolism; lncRNA degradation
regulation of interphase mitotic telomere clustering (GO:0110065)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.
Synonyms: regulation of mitotic telomere clustering during interphase
negative regulation of interphase mitotic telomere clustering (GO:0110066)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of mitotic telomere clustering during interphase.
Synonyms: negative regulation of mitotic telomere clustering during interphase; telomere dispersion during interphase
ammonium transmembrane transporter complex (GO:0110067)
Namespace: cellular_component
Definition: High affinity ammonium transporter complex that enables the transfer of ammonium from one side of a membrane to the other.
Synonyms: AMT1 complex
glucosylglycerate phosphorylase activity (GO:0110068)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate = (R)-glycerate + alpha-D-glucose 1-phosphate.
syncytial embryo cellularization (GO:0110069)
Namespace: biological_process
Definition: The separation of a syncytial embryo into individual cells.
cellularization cleavage furrow (GO:0110070)
Namespace: cellular_component
Definition: A plasma membrane invagination at the site of separation of a multi-nucleate cell or syncytium into individual cells.
cellularization cleavage furrow invagination front (GO:0110071)
Namespace: cellular_component
Definition: The base of the cellularization invagination or cleavage furrow most distal to the original multi-nucleate cell or syncytium plasma membrane.
apical constriction involved in ventral furrow formation (GO:0110072)
Namespace: biological_process
Definition: The actin-mediated process that results in contraction of the apical end of a polarized columnar epithelial cell, contributing to formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
regulation of apical constriction involved in ventral furrow formation (GO:0110073)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of apical constriction involved in ventral furrow formation.
positive regulation of apical constriction involved in ventral furrow formation (GO:0110074)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.
regulation of ferroptosis (GO:0110075)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of ferroptosis.
vesicle-mediated intercellular transport (GO:0110077)
Namespace: biological_process
Definition: A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane.
Synonyms: endosomal trafficking
TTT Hsp90 cochaperone complex (GO:0110078)
Namespace: cellular_component
Definition: A Hsp90 cochaperone complex acting as an adapter between Hps90 and its substrates, members of the PIKK kinase family.
Synonyms: Tel2-Tti1-Tti2; TELO2-TTI1-TTI2; Triple T complex; TTT complex
positive regulation of placenta blood vessel development (GO:0110080)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of placenta blood vessel development.
negative regulation of placenta blood vessel development (GO:0110081)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.
regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly (GO:0110082)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
positive regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly (GO:0110083)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
obsolete negative regulation of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly (GO:0110084)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to cell division site involved in mitotic actomyosin contractile ring assembly.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
mitotic actomyosin contractile ring (GO:0110085)
Namespace: cellular_component
Definition: A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the mitotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the mitotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the mitotic contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.
meiotic actomyosin contractile ring (GO:0110086)
Namespace: cellular_component
Definition: A cytoskeletal structure composed of actin filaments, myosin, and myosin-associated proteins that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the meiotic spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two future daughter cells. In animal cells, the meiotic contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In fungal cells, the meiotic contractile ring forms beneath the plasma membrane of the prospore envelope in preparation for completing cytokinesis.
obsolete suppression by virus of host protease activator activity (GO:0110087)
Namespace: biological_process
Definition: OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protease activator activity.
Comment: This term was obsoleted because it represents a molecular function.
hippocampal neuron apoptotic process (GO:0110088)
Namespace: biological_process
Definition: Any apoptotic process that occurs in a hippocampal neuron.
regulation of hippocampal neuron apoptotic process (GO:0110089)
Namespace: biological_process
Definition: Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.
positive regulation of hippocampal neuron apoptotic process (GO:0110090)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.
nucleus leading edge (GO:0110092)
Namespace: cellular_component
Definition: The area of a motile nucleus closest to the direction of movement.
Synonyms: horsetail nucleus leading edge
nucleus lagging edge (GO:0110093)
Namespace: cellular_component
Definition: The area of a motile nucleus furthest from the direction of movement.