LiteFold/GO huggingface dataset:
obsolete protein histidyl modification to diphthine (GO:0017180)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine.
Synonyms: peptidyl-diphthine anabolism from peptidyl-histidine; peptidyl-diphthine biosynthetic process from peptidyl-histidine; peptidyl-diphthine formation from peptidyl-histidine; peptidyl-diphthine synthesis from peptidyl-histidine
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete peptidyl-diphthine catabolic process (GO:0017181)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue.
Synonyms: peptidyl-diphthine breakdown; peptidyl-diphthine catabolism; peptidyl-diphthine degradation
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete peptidyl-diphthamide metabolic process (GO:0017182)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.
Synonyms: peptidyl-diphthamide metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
protein histidyl modification to diphthamide (GO:0017183)
Namespace: biological_process
Definition: The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
Synonyms: peptidyl-diphthamide anabolism from peptidyl-histidine; peptidyl-diphthamide biosynthetic process from peptidyl-histidine; peptidyl-diphthamide formation from peptidyl-histidine; peptidyl-diphthamide synthesis from peptidyl-histidine
obsolete peptidyl-diphthamide catabolic process (GO:0017184)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue.
Synonyms: peptidyl-diphthamide breakdown; peptidyl-diphthamide catabolism; peptidyl-diphthamide degradation
Comment: This term was obsoleted because there is no evidence that this process exists.
peptidyl-lysine hydroxylation (GO:0017185)
Namespace: biological_process
Definition: The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.
peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase (GO:0017186)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.
Synonyms: 2-pyrrolidone-5-carboxylic acid biosynthesis; 2-pyrrolidone-5-carboxylic acid biosynthetic process; peptidyl-pyroglutamic acid anabolism, using glutaminyl-peptide cyclotransferase; peptidyl-pyroglutamic acid formation, using glutaminyl-peptide cyclotransferase; peptidyl-pyroglutamic acid synthesis, using glutaminyl-peptide cyclotransferase
Comment: See also the molecular function term 'glutaminyl-peptide cyclotransferase activity ; GO:0016603'.
L-aspartate N-acetyltransferase activity (GO:0017188)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H+.
Synonyms: acetyl-CoA:L-aspartate N-acetyltransferase activity; aspartate N-acetyltransferase activity
N-terminal peptidyl-aspartic acid acetylation (GO:0017190)
Namespace: biological_process
Definition: The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.
Comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.
N-terminal peptidyl-glutamine acetylation (GO:0017192)
Namespace: biological_process
Definition: The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.
obsolete N-terminal peptidyl-isoleucine acetylation (GO:0017194)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-lysine N2-acetylation (GO:0017195)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.
Comment: This term was obsoleted because it represents a molecular function.
N-terminal peptidyl-methionine acetylation (GO:0017196)
Namespace: biological_process
Definition: The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.
obsolete N-terminal peptidyl-proline acetylation (GO:0017197)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-serine acetylation (GO:0017198)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-threonine acetylation (GO:0017199)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-tyrosine acetylation (GO:0018000)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-valine acetylation (GO:0018001)
Namespace: biological_process
Definition: OBSOLETE. The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.
Comment: This term was obsoleted because it represents a molecular function.
N-terminal peptidyl-glutamic acid acetylation (GO:0018002)
Namespace: biological_process
Definition: The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.
Comment: See also the molecular function term 'aspartate N-acetyltransferase activity ; GO:0017188'.
peptidyl-lysine N6-acetylation (GO:0018003)
Namespace: biological_process
Definition: The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.
Comment: See also the molecular function term 'tubulin N-acetyltransferase activity ; GO:0019799'.
N-terminal protein formylation (GO:0018004)
Namespace: biological_process
Definition: The formylation of the N-terminal amino acid of proteins.
obsolete N-terminal peptidyl-glycine N-formylation (GO:0018005)
Namespace: biological_process
Definition: OBSOLETE. The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal protein amino acid glucuronylation (GO:0018006)
Namespace: biological_process
Definition: OBSOLETE. The glucuronylation of the N-terminal amino acid of proteins.
Comment: The reason for obsoletion is that this term represents a molecular function
obsolete N-terminal peptidyl-glycine N-glucuronylation (GO:0018007)
Namespace: biological_process
Definition: OBSOLETE. The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.
Comment: The reason for obsoletion is that this term represents a molecular function
N-terminal peptidyl-glycine N-myristoylation (GO:0018008)
Namespace: biological_process
Definition: The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.
Synonyms: N-terminal peptidyl-glycine N-myristylation
N-terminal peptidyl-L-cysteine N-palmitoylation (GO:0018009)
Namespace: biological_process
Definition: The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.
obsolete glycoprotein N-palmitoyltransferase activity (GO:0018010)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.
Synonyms: mucus glycoprotein fatty acyltransferase; palmitoyl-CoA:glycoprotein N-palmitoyltransferase activity
Comment: This term was obsoleted because it has been deleted from EC. The glycoprotein is the product of the reaction.
N-terminal peptidyl-alanine methylation (GO:0018011)
Namespace: biological_process
Definition: The methylation of the N-terminal alanine of proteins.
N-terminal peptidyl-alanine trimethylation (GO:0018012)
Namespace: biological_process
Definition: The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.
N-terminal peptidyl-glycine methylation (GO:0018013)
Namespace: biological_process
Definition: The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
obsolete N-terminal peptidyl-methionine methylation (GO:0018014)
Namespace: biological_process
Definition: OBSOLETE. The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-phenylalanine methylation (GO:0018015)
Namespace: biological_process
Definition: OBSOLETE. The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.
Comment: This term was obsoleted because it represents a molecular function.
N-terminal peptidyl-proline dimethylation (GO:0018016)
Namespace: biological_process
Definition: The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
obsolete N-terminal peptidyl-glutamine methylation (GO:0018019)
Namespace: biological_process
Definition: OBSOLETE. The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.
Comment: This term was obsoleted because it represents a molecular function.
obsolete peptidyl-glutamic acid methylation (GO:0018020)
Namespace: biological_process
Definition: OBSOLETE. The addition of a methyl group to a glutamic acid residue in a protein.
Comment: This term was obsoleted because it represents a molecular function.
peptidyl-histidine methylation (GO:0018021)
Namespace: biological_process
Definition: The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).
peptidyl-lysine methylation (GO:0018022)
Namespace: biological_process
Definition: The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
peptidyl-lysine trimethylation (GO:0018023)
Namespace: biological_process
Definition: The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
obsolete histone lysine N-methyltransferase activity (GO:0018024)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
Synonyms: histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase activity; histone-lysine N-methylase activity; histone-lysine N-methyltransferase activity; S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase activity; S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase activity
Comment: This term was obsoleted because it is an unnecessary grouping class.
calmodulin-lysine N-methyltransferase activity (GO:0018025)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.
Synonyms: S-adenosyl-L-methionine:calmodulin-L-lysine 6-N-methyltransferase activity; S-adenosyl-L-methionine:calmodulin-L-lysine N6-methyltransferase activity; S-adenosylmethionine:calmodulin (lysine) N-methyltransferase activity
peptidyl-lysine monomethylation (GO:0018026)
Namespace: biological_process
Definition: The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
peptidyl-lysine dimethylation (GO:0018027)
Namespace: biological_process
Definition: The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.
obsolete peptidyl-lysine myristoylation (GO:0018028)
Namespace: biological_process
Definition: OBSOLETE. The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.
Synonyms: peptidyl-lysine myristylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete peptidyl-lysine palmitoylation (GO:0018029)
Namespace: biological_process
Definition: OBSOLETE. The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.
Comment: This term was obsoleted because it represents a molecular function.
peptidyl-lysine N6-myristoyltransferase activity (GO:0018030)
Namespace: molecular_function
Definition: Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.
obsolete protein amidation (GO:0018032)
Namespace: biological_process
Definition: OBSOLETE. Addition of an amide group from a glycine to a protein amino acid.
Synonyms: protein amino acid amidation
Comment: This term was obsoleted because it represents a molecular function.
obsolete protein C-terminal amidation (GO:0018033)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function.
obsolete C-terminal peptidyl-alanine amidation (GO:0018034)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-arginine amidation (GO:0018035)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-aspartic acid amidation (GO:0018037)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-cysteine amidation (GO:0018038)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-glutamine amidation (GO:0018039)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-glutamic acid amidation (GO:0018040)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-histidine amidation (GO:0018042)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-isoleucine amidation (GO:0018043)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-leucine amidation (GO:0018044)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-lysine amidation (GO:0018045)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-methionine amidation (GO:0018046)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-phenylalanine amidation (GO:0018047)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-proline amidation (GO:0018048)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-serine amidation (GO:0018049)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-threonine amidation (GO:0018050)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-tryptophan amidation (GO:0018051)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-tyrosine amidation (GO:0018052)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete C-terminal peptidyl-valine amidation (GO:0018053)
Namespace: biological_process
Definition: OBSOLETE. The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.
Comment: This term was obsoleted because it represents a molecular function, and this modification is not known to exist; only c-terminal peptidylglycine has been identified, see PMID:35124797.
obsolete peptidyl-lysine biotinylation (GO:0018054)
Namespace: biological_process
Definition: OBSOLETE. The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.
Comment: This terms was obsoleted because it represents a molecular function as a biological process.
peptidyl-lysine oxidation (GO:0018057)
Namespace: biological_process
Definition: The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.
obsolete N-terminal peptidyl-serine deamination (GO:0018059)
Namespace: biological_process
Definition: OBSOLETE. The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-cysteine deamination (GO:0018060)
Namespace: biological_process
Definition: OBSOLETE. The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
Comment: This term was obsoleted because it represents a molecular function.