LiteFold/GO huggingface dataset:
primary miRNA processing (GO:0031053)
Namespace: biological_process
Definition: A process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
Synonyms: pri-miRNA processing; primary microRNA processing; primary miRNA methylation; primary miRNA modification
obsolete chromatin remodeling at centromere (GO:0031055)
Namespace: biological_process
Definition: OBSOLETE. Dynamic structural changes in centromeric DNA.
Synonyms: chromatin remodelling at centromere
Comment: This term was obsoleted because it represents the same process as CENP-A containing chromatin assembly ; GO:0034080.
obsolete regulation of histone modification (GO:0031056)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of histone modification (GO:0031057)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone.
Synonyms: down regulation of histone modification; down-regulation of histone modification; downregulation of histone modification; inhibition of histone modification
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of histone modification (GO:0031058)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone.
Synonyms: activation of histone modification; stimulation of histone modification; up regulation of histone modification; up-regulation of histone modification; upregulation of histone modification
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone deacetylation at centromere (GO:0031059)
Namespace: biological_process
Definition: OBSOLETE. The removal of acetyl groups from histones in centromeric DNA.
Comment: This term was obsoleted because it represents a molecular function as a biological process, and contains cellular component information.
obsolete regulation of histone methylation (GO:0031060)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of histone methylation (GO:0031061)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
Synonyms: down regulation of histone methylation; down-regulation of histone methylation; downregulation of histone methylation; inhibition of histone methylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of histone deacetylation (GO:0031063)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of histone deacetylation (GO:0031064)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones.
Synonyms: down regulation of histone deacetylation; down-regulation of histone deacetylation; downregulation of histone deacetylation; inhibition of histone deacetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of histone deacetylation at centromere (GO:0031066)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.
Comment: This term was obsoleted because it represents a molecular function as a biological process, and contains cellular component information.
obsolete negative regulation of histone deacetylation at centromere (GO:0031067)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA.
Synonyms: down regulation of histone deacetylation at centromere; down-regulation of histone deacetylation at centromere; downregulation of histone deacetylation at centromere; inhibition of histone deacetylation at centromere
Comment: This term was obsoleted because it represents a molecular function as a biological process, and contains cellular component information.
obsolete positive regulation of histone deacetylation at centromere (GO:0031068)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.
Synonyms: activation of histone deacetylation at centromere; stimulation of histone deacetylation at centromere; up regulation of histone deacetylation at centromere; up-regulation of histone deacetylation at centromere; upregulation of histone deacetylation at centromere
Comment: This term was obsoleted because it represents a molecular function as a biological process, and contains cellular component information.
hair follicle morphogenesis (GO:0031069)
Namespace: biological_process
Definition: The process in which the anatomical structures of the hair follicle are generated and organized.
intronic snoRNA processing (GO:0031070)
Namespace: biological_process
Definition: The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.
heat shock protein binding (GO:0031072)
Namespace: molecular_function
Definition: Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.
cholesterol 26-hydroxylase activity (GO:0031073)
Namespace: molecular_function
Definition: Catalysis of the reaction: cholesterol + H+ NADPH + O2 = 26-hydroxycholesterol + H2O + NADP+.
nucleocytoplasmic transport complex (GO:0031074)
Namespace: cellular_component
Definition: Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.
Synonyms: nucleocytoplasmic shuttling complex
embryonic camera-type eye development (GO:0031076)
Namespace: biological_process
Definition: The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
Synonyms: embryonic eye development
post-embryonic camera-type eye development (GO:0031077)
Namespace: biological_process
Definition: The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.
Synonyms: post-embryonic camera-style eye development
histone H3K14 deacetylase activity, hydrolytic mechanism (GO:0031078)
Namespace: molecular_function
Definition: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
Synonyms: histone deacetylase activity (H3-K14 specific); histone H3-K14 deacetylase activity; histone H3K14 deacetylase activity
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
obsolete picornain 3C activity (GO:0031079)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the selective cleavage of GlnGly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Synonyms: 3C protease activity; 3C proteinase activity; coxsackievirus 3C proteinase activity; cysteine proteinase 3C; foot-and-mouth protease 3C activity; foot-and-mouth-disease virus proteinase 3C; hepatitis A virus 3C proteinase activity; picornain 3C activity; picornavirus endopeptidase 3C activity; poliovirus protease 3C activity; poliovirus proteinase 3C; protease 3C; rhinovirus protease 3C activity; rhinovirus proteinase 3C; tomato ringspot nepovirus 3C-related protease
Comment: This term was made obsolete because it represents a gene product.
nuclear pore outer ring (GO:0031080)
Namespace: cellular_component
Definition: A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).
Synonyms: Nup107-120 complex; Nup107-160 complex; Nup84 complex
BLOC complex (GO:0031082)
Namespace: cellular_component
Definition: Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.
Synonyms: BLOC-1 related complex
BLOC-2 complex (GO:0031084)
Namespace: cellular_component
Definition: A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.
BLOC-3 complex (GO:0031085)
Namespace: cellular_component
Definition: A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.
deadenylation-independent decapping of nuclear-transcribed mRNA (GO:0031087)
Namespace: biological_process
Definition: Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.
Synonyms: deadenylation-independent decapping of nuclear mRNA; deadenylylation-independent decapping
platelet dense granule membrane (GO:0031088)
Namespace: cellular_component
Definition: The lipid bilayer surrounding the platelet dense granule.
platelet dense granule lumen (GO:0031089)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of the platelet dense granule.
organelle membrane (GO:0031090)
Namespace: cellular_component
Definition: A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
Synonyms: intracellular membrane
platelet alpha granule (GO:0031091)
Namespace: cellular_component
Definition: A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
Synonyms: platelet alpha-granule
platelet alpha granule membrane (GO:0031092)
Namespace: cellular_component
Definition: The lipid bilayer surrounding the platelet alpha granule.
Synonyms: platelet alpha-granule membrane
platelet alpha granule lumen (GO:0031093)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of the platelet alpha granule.
Synonyms: platelet alpha-granule lumen
platelet dense tubular network (GO:0031094)
Namespace: cellular_component
Definition: A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.
platelet dense tubular network membrane (GO:0031095)
Namespace: cellular_component
Definition: The lipid bilayer surrounding the platelet dense tubular network.
platelet dense tubular network lumen (GO:0031096)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of the platelet dense tubular network.
medial cortex (GO:0031097)
Namespace: cellular_component
Definition: A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
Synonyms: medial ring
regeneration (GO:0031099)
Namespace: biological_process
Definition: The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).
animal organ regeneration (GO:0031100)
Namespace: biological_process
Definition: The regrowth of a lost or destroyed animal organ.
neuron projection regeneration (GO:0031102)
Namespace: biological_process
Definition: The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.
Synonyms: neurite regeneration
axon regeneration (GO:0031103)
Namespace: biological_process
Definition: The regrowth of axons following their loss or damage.
dendrite regeneration (GO:0031104)
Namespace: biological_process
Definition: The regrowth of dendrites in response to their loss or damage.
septin complex (GO:0031105)
Namespace: cellular_component
Definition: A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
septin ring organization (GO:0031106)
Namespace: biological_process
Definition: Control of the formation, spatial distribution, and breakdown of the septin ring.
Synonyms: septin ring organisation
septin ring disassembly (GO:0031107)
Namespace: biological_process
Definition: The controlled breakdown of a septin ring.
holo-[acyl-carrier-protein] biosynthetic process (GO:0031108)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].
Synonyms: holo-[acyl-carrier protein] biosynthesis; holo-[acyl-carrier-protein] anabolism; holo-[acyl-carrier-protein] biosynthesis; holo-[acyl-carrier-protein] formation; holo-[acyl-carrier-protein] synthesis
microtubule polymerization or depolymerization (GO:0031109)
Namespace: biological_process
Definition: Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
Synonyms: microtubule dynamics
regulation of microtubule polymerization or depolymerization (GO:0031110)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
negative regulation of microtubule polymerization or depolymerization (GO:0031111)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.
Synonyms: down regulation of microtubule polymerization or depolymerization; down-regulation of microtubule polymerization or depolymerization; downregulation of microtubule polymerization or depolymerization; inhibition of microtubule polymerization or depolymerization
positive regulation of microtubule polymerization or depolymerization (GO:0031112)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.
Synonyms: activation of microtubule polymerization or depolymerization; stimulation of microtubule polymerization or depolymerization; up regulation of microtubule polymerization or depolymerization; up-regulation of microtubule polymerization or depolymerization; upregulation of microtubule polymerization or depolymerization
regulation of microtubule polymerization (GO:0031113)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of microtubule polymerization.
regulation of microtubule depolymerization (GO:0031114)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of microtubule depolymerization.
Synonyms: regulation of microtubule disassembly
negative regulation of microtubule polymerization (GO:0031115)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
Synonyms: down regulation of microtubule polymerization; down-regulation of microtubule polymerization; downregulation of microtubule polymerization; inhibition of microtubule polymerization
positive regulation of microtubule polymerization (GO:0031116)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
Synonyms: activation of microtubule polymerization; stimulation of microtubule polymerization; up regulation of microtubule polymerization; up-regulation of microtubule polymerization; upregulation of microtubule polymerization
positive regulation of microtubule depolymerization (GO:0031117)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
Synonyms: activation of microtubule depolymerization; microtubule destabilization; positive regulation of microtubule catastrophe; positive regulation of microtubule disassembly; stimulation of microtubule depolymerization; up regulation of microtubule depolymerization; up-regulation of microtubule depolymerization; upregulation of microtubule depolymerization
rRNA pseudouridine synthesis (GO:0031118)
Namespace: biological_process
Definition: The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
tRNA pseudouridine synthesis (GO:0031119)
Namespace: biological_process
Definition: The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
snRNA pseudouridine synthesis (GO:0031120)
Namespace: biological_process
Definition: The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
equatorial microtubule organization (GO:0031121)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.
Synonyms: equatorial microtubule organisation; equatorial microtubule organization and biogenesis
cytoplasmic microtubule organization (GO:0031122)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
Synonyms: cytoplasmic microtubule organisation; cytoplasmic microtubule organization and biogenesis
RNA 3'-end processing (GO:0031123)
Namespace: biological_process
Definition: Any process involved in forming the mature 3' end of an RNA molecule.
Synonyms: RNA 3' end processing
mRNA 3'-end processing (GO:0031124)
Namespace: biological_process
Definition: Any process involved in forming the mature 3' end of an mRNA molecule.
Synonyms: mRNA 3' end processing
sno(s)RNA 3'-end processing (GO:0031126)
Namespace: biological_process
Definition: Any process involved in forming the mature 3' end of a snoRNA family molecule, also referred to as an sRNA in Archaea.
Synonyms: sno(s)RNA 3' end processing; snoRNA 3'-end processing; sRNA 3'-end processing
alpha-(1,2)-fucosyltransferase activity (GO:0031127)
Namespace: molecular_function
Definition: Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.
Synonyms: alpha-(1->2)-fucosyltransferase activity; alpha-1,2-fucosyltransferase activity
developmental induction (GO:0031128)
Namespace: biological_process
Definition: A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).
inductive cell-cell signaling (GO:0031129)
Namespace: biological_process
Definition: Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.
Synonyms: inductive cell-cell signalling
obsolete creation of an inductive signal (GO:0031130)
Namespace: biological_process
Definition: OBSOLETE. The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter.
Comment: The reason for obsoletion is that the term is not clearly defined and there is no annotations.
obsolete reception of an inductive signal (GO:0031131)
Namespace: biological_process
Definition: OBSOLETE. The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.
Comment: The reason for obsoletion is that these are pre-composed terms that represent a cell-surface signaling pathway during some developmental process.
serine 3-dehydrogenase activity (GO:0031132)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-serine + NADP+ = L-alpha-formylglycine + 2 H+ + NADPH.
Synonyms: L-serine:NADP+ 3-oxidoreductase activity
sister chromatid biorientation (GO:0031134)
Namespace: biological_process
Definition: The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
Synonyms: chromosome biorientation; sister kinetochore biorientation
obsolete negative regulation of conjugation (GO:0031135)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate of conjugation.
Synonyms: down regulation of conjugation; down-regulation of conjugation; downregulation of conjugation; inhibition of conjugation
Comment: This term was obsoleted because its target (conjugation) was not clearly defined.
obsolete positive regulation of conjugation (GO:0031136)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate or frequency of conjugation.
Synonyms: activation of conjugation; stimulation of conjugation; up regulation of conjugation; up-regulation of conjugation; upregulation of conjugation
Comment: This term was obsoleted because its target (conjugation) was not clearly defined.
regulation of conjugation with cellular fusion (GO:0031137)
Namespace: biological_process
Definition: Any process that modulates the rate or frequency of conjugation with cellular fusion.
negative regulation of conjugation with cellular fusion (GO:0031138)
Namespace: biological_process
Definition: Any process that decreases the rate or frequency of conjugation with cellular fusion.
Synonyms: down regulation of conjugation with cellular fusion; down-regulation of conjugation with cellular fusion; downregulation of conjugation with cellular fusion; inhibition of conjugation with cellular fusion