LiteFold/GO huggingface dataset:
host cell nuclear inner membrane (GO:0044201)
Namespace: cellular_component
Definition: The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.
host cell nuclear outer membrane (GO:0044202)
Namespace: cellular_component
Definition: The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.
host cell nuclear lamina (GO:0044203)
Namespace: cellular_component
Definition: The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.
host cell nuclear matrix (GO:0044204)
Namespace: cellular_component
Definition: A dynamic, proteinaceous framework within the nucleus of host eukaryotic cells, composed of proteins and RNA, that provides structural support for chromatin organization, gene regulation, and nuclear processes.
'de novo' UMP biosynthetic process (GO:0044205)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD+ or oxygen.
Synonyms: 'de novo' UMP biosynthesis
UMP salvage (GO:0044206)
Namespace: biological_process
Definition: Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.
Synonyms: UMP biosynthesis via nucleoside salvage pathway; UMP biosynthetic process via nucleoside salvage pathway
translation initiation ternary complex (GO:0044207)
Namespace: cellular_component
Definition: A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
Synonyms: Met-tRNA/eIF2.GTP ternary complex; translation initiation (ternary) complex
'de novo' AMP biosynthetic process (GO:0044208)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).
AMP salvage (GO:0044209)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.
Synonyms: adenosine monophosphate salvage; AMP biosynthetic process via salvage pathway
'de novo' CTP biosynthetic process (GO:0044210)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
Synonyms: 'de novo' cytidine 5'-triphosphate biosynthetic process
obsolete spanning component of plasma membrane (GO:0044214)
Namespace: cellular_component
Definition: OBSOLETE. The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
Synonyms: fully spanning plasma membrane; transmembrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete other organism cell (GO:0044216)
Namespace: cellular_component
Definition: OBSOLETE. A cell of a secondary organism with which the first organism is interacting.
Comment: This term was obsoleted because cell (and therefore 'other organism cell') was considered outside the scope of GO.
other organism part (GO:0044217)
Namespace: cellular_component
Definition: Any constituent part of a secondary organism with which the first organism is interacting.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
other organism cell membrane (GO:0044218)
Namespace: cellular_component
Definition: The cell membrane of a secondary organism with which the first organism is interacting.
Synonyms: foreign membrane; other organism membrane
host cell plasmodesma (GO:0044219)
Namespace: cellular_component
Definition: A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.
host cell perinuclear region of cytoplasm (GO:0044220)
Namespace: cellular_component
Definition: The host cell cytoplasm situated near, or occurring around, the host nucleus.
host cell synapse (GO:0044221)
Namespace: cellular_component
Definition: The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.
anammoxosome (GO:0044222)
Namespace: cellular_component
Definition: An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.
pirellulosome (GO:0044223)
Namespace: cellular_component
Definition: A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.
apical pole of neuron (GO:0044225)
Namespace: cellular_component
Definition: Portion of a neuron cell soma closest to the point where the apical dendrite emerges.
methane-oxidizing organelle (GO:0044227)
Namespace: cellular_component
Definition: A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.
Synonyms: methane-oxidizing compartment; methanotroph intracytoplasmic membrane-bound compartment
host cell surface (GO:0044228)
Namespace: cellular_component
Definition: The external part of the host cell wall and/or host plasma membrane.
host cell periplasmic space (GO:0044229)
Namespace: cellular_component
Definition: The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).
primary metabolic process (GO:0044238)
Namespace: biological_process
Definition: The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
Synonyms: primary metabolism
obsolete salivary polysaccharide catabolic process (GO:0044239)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.
Synonyms: salivary polysaccharide breakdown; salivary polysaccharide catabolism; salivary polysaccharide degradation
Comment: The reason for obsoletion is that this term represents the location of a process, which should be captured by the relation 'occurs in'.
lipid digestion (GO:0044241)
Namespace: biological_process
Definition: The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
obsolete cellular lipid catabolic process (GO:0044242)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
Synonyms: cellular lipid breakdown; cellular lipid catabolism; cellular lipid degradation
Comment: The reason for obsoletion is that this terms is redundant with GO:0016042
obsolete cellular polysaccharide catabolic process (GO:0044247)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells.
Synonyms: cellular polysaccharide breakdown; cellular polysaccharide catabolism; cellular polysaccharide degradation
Comment: This term was obsoleted because it is not different from its parent, polysaccharide catabolic process ; GO:0000272.
obsolete cellular catabolic process (GO:0044248)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
Synonyms: cellular breakdown; cellular catabolism; cellular degradation
Comment: The reason for obsoletion is that cellular x metabolic process are being replaced with corresponding 'x metabolic process'
obsolete cellular biosynthetic process (GO:0044249)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
Synonyms: cellular anabolism; cellular biosynthesis; cellular formation; cellular synthesis
Comment: The reason for obsoletion is that this term is now redundant with GO:0009058, biosynthetic process
obsolete negative regulation of metabolic activity involved in hibernation (GO:0044250)
Namespace: biological_process
Definition: OBSOLETE. The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.
Synonyms: down regulation of metabolic activity during hibernation; down-regulation of metabolic activity during hibernation; downregulation of metabolic activity during hibernation; inhibition of metabolic activity during hibernation; negative regulation of metabolic activity during hibernation
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete protein catabolic process by pepsin (GO:0044251)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).
Synonyms: protein breakdown by pepsin; protein degradation by pepsin
Comment: The reason for obsoletion is that this term represents a specific gene product.
obsolete cellular lipid metabolic process (GO:0044255)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving lipids, as carried out by individual cells.
Synonyms: cellular lipid metabolism
Comment: The reason for obsoletion is that this term is redundant to GO:0006629
protein digestion (GO:0044256)
Namespace: biological_process
Definition: The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.
intestinal lipid catabolic process (GO:0044258)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.
Synonyms: intestinal lipid breakdown; intestinal lipid catabolism; intestinal lipid degradation
obsolete cellular macromolecule metabolic process (GO:0044260)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
Synonyms: cellular biopolymer metabolic process; cellular macromolecule metabolism
Comment: This term was obsoleted because it is not different from its parent, macromolecule metabolic process ; GO:0043170.
obsolete cellular carbohydrate metabolic process (GO:0044262)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
Synonyms: cellular carbohydrate metabolism; main pathways of carbohydrate metabolic process; main pathways of carbohydrate metabolism
Comment: This term was obsoleted because it is not different from its parent, carbohydrate metabolic process ; GO:0005975.
obsolete cellular polysaccharide metabolic process (GO:0044264)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
Synonyms: cellular glycan metabolic process; cellular glycan metabolism; cellular polysaccharide metabolism
Comment: This term was obsoleted because it is not different from its parent, polysaccharide metabolic process ; GO:0005976.
obsolete cellular macromolecule catabolic process (GO:0044265)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
Synonyms: cellular biopolymer catabolic process; cellular macromolecule breakdown; cellular macromolecule catabolism; cellular macromolecule degradation
Comment: This term was obsoleted because it is not different from its parent, macromolecule catabolic process ; GO:0009057.
glycerol ether catabolic process (GO:0044269)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
Synonyms: glycerol ether breakdown; glycerol ether catabolism; glycerol ether degradation
obsolete cellular nitrogen compound catabolic process (GO:0044270)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete cellular nitrogen compound biosynthetic process (GO:0044271)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
sulfur compound biosynthetic process (GO:0044272)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
Synonyms: sulfur biosynthesis; sulfur biosynthetic process; sulfur compound anabolism; sulfur compound biosynthesis; sulfur compound formation; sulfur compound synthesis
sulfur compound catabolic process (GO:0044273)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
Synonyms: sulfur catabolic process; sulfur catabolism; sulfur compound breakdown; sulfur compound catabolism; sulfur compound degradation
obsolete cellular carbohydrate catabolic process (GO:0044275)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
Synonyms: cellular carbohydrate breakdown; cellular carbohydrate catabolism; cellular carbohydrate degradation
Comment: This term was obsoleted because it is not different from its parent, carbohydrate catabolic process ; GO:0016052.
cell wall disassembly (GO:0044277)
Namespace: biological_process
Definition: A process that results in the breakdown of the cell wall.
Synonyms: cellular cell wall disassembly
venom-mediated disruption of cell wall in another organism (GO:0044278)
Namespace: biological_process
Definition: The disruption of the cell wall of another organism by a venom, leading to damage or temporary subversion of the cell wall.
Synonyms: cell wall disruption in another organism; cell wall disruption in other organism
subplasmalemmal coating (GO:0044280)
Namespace: cellular_component
Definition: Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.
small molecule metabolic process (GO:0044281)
Namespace: biological_process
Definition: The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
Synonyms: small molecule metabolism
Comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
small molecule catabolic process (GO:0044282)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.
Synonyms: small molecule catabolism
Comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
mitochondrial crista junction (GO:0044284)
Namespace: cellular_component
Definition: A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.
Synonyms: crista junction; cristae junction
peg and socket contact (GO:0044286)
Namespace: cellular_component
Definition: A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.
Synonyms: ball and socket contact
puncta adhaerentia (GO:0044288)
Namespace: cellular_component
Definition: A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.
mitochondrial inner-outer membrane contact site (GO:0044289)
Namespace: cellular_component
Definition: Sites of close apposition of the inner and outer mitochondrial membrane.
Synonyms: bridge contact site; contact site
mitochondrial intracristal space (GO:0044290)
Namespace: cellular_component
Definition: The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.
cell-cell contact zone (GO:0044291)
Namespace: cellular_component
Definition: Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
Synonyms: cell cell contact zone
dendrite terminus (GO:0044292)
Namespace: cellular_component
Definition: A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.
Synonyms: dendrite terminal; dendrite terminal specialization; terminal specialization; terminal specialization of a dendrite
dendriole (GO:0044293)
Namespace: cellular_component
Definition: Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).
dendritic growth cone (GO:0044294)
Namespace: cellular_component
Definition: The migrating motile tip of a growing nerve cell dendrite.
Synonyms: dendrite growth cone
axonal growth cone (GO:0044295)
Namespace: cellular_component
Definition: The migrating motile tip of a growing nerve cell axon.
Synonyms: axon growth cone
dendritic tuft (GO:0044296)
Namespace: cellular_component
Definition: The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.
Synonyms: dendrite tuft
cell body membrane (GO:0044298)
Namespace: cellular_component
Definition: The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.
Synonyms: cell soma membrane
C-fiber (GO:0044299)
Namespace: cellular_component
Definition: The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.
Synonyms: C-fibre
cerebellar mossy fiber (GO:0044300)
Namespace: cellular_component
Definition: An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations.
Synonyms: cerebellar mossy fibre
climbing fiber (GO:0044301)
Namespace: cellular_component
Definition: The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to climb along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.
Synonyms: climbing fibre
dentate gyrus mossy fiber (GO:0044302)
Namespace: cellular_component
Definition: Hippocampal mossy fiber produced by dentate gyrus granule cells.
Synonyms: dentate gyrus mossy fibre; granule cell axon
axon collateral (GO:0044303)
Namespace: cellular_component
Definition: Any of the smaller branches of an axon that emanate from the main axon cylinder.
main axon (GO:0044304)
Namespace: cellular_component
Definition: The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.
Synonyms: axon shaft; axon trunk; axonal shaft
calyx of Held (GO:0044305)
Namespace: cellular_component
Definition: The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
neuron projection terminus (GO:0044306)
Namespace: cellular_component
Definition: The specialized, terminal region of a neuron projection such as an axon or a dendrite.
Synonyms: nerve terminal; neuron projection terminal; neuron terminal specialization
dendritic branch (GO:0044307)
Namespace: cellular_component
Definition: A dendrite arising from another dendrite.
Synonyms: dendrite branch; secondary dendrite
axonal spine (GO:0044308)
Namespace: cellular_component
Definition: A spine that originates from the axon, usually from the initial segment.
Synonyms: axon spine
neuron spine (GO:0044309)
Namespace: cellular_component
Definition: A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
Synonyms: spine
osmiophilic body (GO:0044310)
Namespace: cellular_component
Definition: A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.
exoneme (GO:0044311)
Namespace: cellular_component
Definition: A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.