LiteFold/GO huggingface dataset:
cold-induced thermogenesis (GO:0106106)
Namespace: biological_process
Definition: The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.
Synonyms: CIT
regulation of (R)-mevalonic acid biosynthetic process (GO:0106107)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
negative regulation of (R)-mevalonic acid biosynthetic process (GO:0106108)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
positive regulation of (R)-mevalonic acid biosynthetic process (GO:0106109)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.
vomitoxin biosynthetic process (GO:0106110)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.
Synonyms: deoxynivalenol biosynthetic process; DON biosynthetic process; vomitoxin anabolism; vomitoxin biosynthesis; vomitoxin formation; vomitoxin synthesis
obsolete regulation of mitotic cohesin ssDNA (lagging strand) loading (GO:0106111)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
obsolete negative regulation of mitotic cohesin ssDNA (lagging strand) loading (GO:0106112)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
obsolete positive regulation of mitotic cohesin ssDNA (lagging strand) loading (GO:0106113)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
obsolete regulation of mitotic cohesin dsDNA (leading strand) loading (GO:0106114)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
obsolete positive regulation of mitotic cohesin dsDNA (leading strand) loading (GO:0106116)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
acidocalcisome organization (GO:0106117)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an acidocalcisome. An acidocalcisome is an electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
Synonyms: acidocalcisome biogenesis; acidocalcisome organisation; acidocalcisome organization and biogenesis; metachromatic granule organization; polyphosphate vacuole organization; volutin granule organization
regulation of sterol biosynthetic process (GO:0106118)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a sterol biosynthetic process.
negative regulation of sterol biosynthetic process (GO:0106119)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of a sterol biosynthetic process.
positive regulation of cobalamin metabolic process (GO:0106121)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.
negative regulation of cobalamin metabolic process (GO:0106122)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.
reservosome (GO:0106123)
Namespace: cellular_component
Definition: A large membrane-bound endocytic organelle present only in members of the Schizotrypanum subgenus of the Trypanosoma genus and is defined as the site of storage of endocytosed macromolecules and lysosomal enzymes. It is found at the posterior end of epimastigote forms of Trypanosoma cruzi, but absent in amastigotes and trypomastigotes.
reservosome lumen (GO:0106124)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of a reservosome.
reservosome matrix (GO:0106125)
Namespace: cellular_component
Definition: A matrix composed of planar membranes, vesicles and lipid inclusions within the reservosome.
reservosome membrane (GO:0106126)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a reservosome.
negative regulation of store-operated calcium entry (GO:0106128)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium entry.
purine phosphoribosyltransferase activity (GO:0106130)
Namespace: molecular_function
Definition: Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.
positive regulation of cardiac muscle cell contraction (GO:0106134)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cardiac muscle cell contraction.
lectin-induced modified bacterial internalization (GO:0106136)
Namespace: biological_process
Definition: The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
Synonyms: LIMBI
IkappaB kinase complex binding (GO:0106137)
Namespace: molecular_function
Definition: Binding to a IkappaB kinase complex.
Sec61 translocon complex binding (GO:0106138)
Namespace: molecular_function
Definition: Binding to a Sec61 translocon complex.
symbiont cell surface (GO:0106139)
Namespace: cellular_component
Definition: The cell surface of a secondary, endosymbiont organism with which the first organism is interacting. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
Synonyms: endosymbiont cell surface
P-TEFb complex binding (GO:0106140)
Namespace: molecular_function
Definition: Binding to a P-TEFb complex.
flavin prenyltransferase activity (GO:0106141)
Namespace: molecular_function
Definition: Catalysis of the reaction: dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2.
rRNA (adenine-N1-)-methyltransferase activity (GO:0106142)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + adenine(645) in 25S rRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(645) in 25S rRNA.
Synonyms: 25S rRNA (adenine(645)-N(1))-methyltransferase; 25S rRNA m(1)A(645) methyltransferase
Comment: The m(1)A modification at position 645 in the large rRNA is highly conserved in eukaryotes.
tRNA (m7G46) methyltransferase complex (GO:0106143)
Namespace: cellular_component
Definition: A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).
Synonyms: Trm8-Trm82 complex; tRNA (m7G46) methyltransferase; tRNA m7G methylation complex
fraxetin 5-hydroxylase activity (GO:0106144)
Namespace: molecular_function
Definition: Catalyzes the reaction fraxetin+ NAD(P)H + 02= sideretin + NAD(P)(+) + H20.
scopoletin 8-hydroxylase activity (GO:0106145)
Namespace: molecular_function
Definition: Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2).
sideretin biosynthesis (GO:0106146)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of sideretin.
fraxetin biosynthesis (GO:0106147)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of fraxetin.
4-hydroxyindole-3- carbonyl nitrile biosynthesis (GO:0106148)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.
zearalenone biosynthetic process (GO:0106150)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of zearalenone, a mycotoxin produced by several Fusarium species, is most commonly found as a contaminant in stored grain and has chronic estrogenic effects on mammals.
CNBH domain intrinsic ligand binding (GO:0106151)
Namespace: molecular_function
Definition: Interacting selectivity and noncovalently with a cyclic nucleotide mimicking protein motif that is part of the same protein. The CNBHD is a domain on KCNH channels that creates a binding pocket on the KCNH channel that resembles the cyclic nucleotide- binding domain on other ion channels. It binds to a peptide motif that is part of the same protein rather than a cyclic nucleotide.
Comment: It is unclear if the motif bound by CNBHD is a specific motif or just a beta sheet with the appropriate amino acids.
obsolete phosphorylated histone binding (GO:0106153)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a histone in which a residue has been modified by phosphorylation.
Comment: This term was obsoleted in favor of histone reader avctivity ; GO:0140566.
perithecium formation (GO:0106154)
Namespace: biological_process
Definition: The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.
peptidyl-lysine 3-dioxygenase activity (GO:0106155)
Namespace: molecular_function
Definition: Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 3-hydroxy-L-lysine + succinate + CO2.
peptidyl-lysine 4-dioxygenase activity (GO:0106156)
Namespace: molecular_function
Definition: Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.
peptidyl-arginine 3-dioxygenase activity (GO:0106157)
Namespace: molecular_function
Definition: Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.
Synonyms: L-arginine 3-hydroxylase activity
glycero-3-phosphocholine acyltransferase activity (GO:0106158)
Namespace: molecular_function
Definition: Catalysis of the reaction:acyl-CoA + glycerophosphocholine = CoA + 1-acyl-sn-glycero-3-phosphocholine.
Synonyms: glycerophosphocholine O-acyltransferase activity; GPACT activity
obsolete regulation of small RNA loading onto RISC (GO:0106159)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent small RNA loading onto RISC.
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete negative regulation of small RNA loading onto RISC (GO:0106160)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of small RNA loading onto RISC.
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete positive regulation of small RNA loading onto RISC (GO:0106161)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of small RNA loading onto RISC.
Comment: This term was obsoleted because there is no evidence that this process exists.
mRNA cytidine N-acetyltransferase activity (GO:0106162)
Namespace: molecular_function
Definition: Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H+ + phosphate.
Synonyms: mRNA N-acetyltransferase activity
obsolete regulation of exonucleolytic catabolism of deadenylated mRNA (GO:0106163)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
obsolete positive regulation of exonucleolytic catabolism of deadenylated mRNA (GO:0106164)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
obsolete negative regulation of exonucleolytic catabolism of deadenylated mRNA (GO:0106165)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay.
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.
spindle pole body-nuclear membrane anchor activity (GO:0106166)
Namespace: molecular_function
Definition: The binding activity of a molecule that brings together a mitotic spindle pole body and the nuclear membrane, in order to maintain specific membrane location of the spindle pole body.
Synonyms: nuclear membrane-spindle pole body anchor activity; spindle pole body nuclear membrane anchor activity
extracellular ATP signaling (GO:0106167)
Namespace: biological_process
Definition: The series of molecular signals mediated by the detection of extracellular ATP.
COPI-coated vesicle lumen (GO:0106172)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of a COPI-coated endocytic vesicle.
COPII-coated vesicle lumen (GO:0106173)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of a COPII-coated endocytic vesicle.
phagolysosome vesicle membrane (GO:0106175)
Namespace: cellular_component
Definition: The lipid bylayer surrounding a phagolysosome.
clathrin-coated endocytic vesicle lumen (GO:0106176)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of a clathrin-coated endocytic vesicle.
obsolete translocase activity (GO:0106178)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis the movement of ions or molecules across membranes or their separation within membranes.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic cations and their chelates (GO:0106179)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity of hydrons (GO:0106180)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of hydrons (hydron being the general name for H+ in its natural abundance).
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on amino acids and peptides. (GO:0106182)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of amino acids and peptides.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on carbohydrates and their derivatives. (GO:0106183)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of carbohydrates and their derivatives.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocation activity acting on other compounds (GO:0106184)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of other compounds not included in EC:7.1 through EC:7.5 .
Comment: This term was made obsolete because the name and scope ( other compounds not included in EC:7.1 through EC:7.5 ) is not good ontological practice.
obsolete histone H3-K37 methylation (GO:0106185)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by addition of one or more methyl groups to lysine at position 37 of the histone.
Synonyms: histone H3 K37 methylation; histone H3K37me; histone lysine H3 K37 methylation
Comment: This term was obsoleted because it represents a molecular function.
cytoplasmic side of plasma membrane, cell tip (GO:0106186)
Namespace: cellular_component
Definition: The leaflet the plasma membrane at the cell tip that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it.
obsolete translocase activity acting on hydrons linked to oxidoreductase reactions (GO:0106187)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of hydrons linked to an oxidoreduction reaction.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on hydrons linked the hydrolysis of a nucleoside triphosphate (GO:0106188)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a nucleoside triphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on hydrons linked to the hydrolysis of a diphosphate (GO:0106189)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of hydrons linked to the hydrolysis of a diphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on hydrons linked to a decarboxylation reaction (GO:0106190)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of hydrons linked to a decarboxylation reaction.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inogranic cations linked to oxidoreductase reactions (GO:0106191)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic cations linked to oxidoreductase reactions.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate (GO:0106192)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a nucleoside triphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic cations and their chelates linked to the hydrolysis of a diphosphate (GO:0106193)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic cations and their chelates linked to the hydrolysis of a diphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic cations and their chelates linked to a decarboxylation reaction (GO:0106194)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transocation of inorganic cations and their chelates linked to a decarboxylation reaction.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic anions linked to oxidoreductase reactions (GO:0106195)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic anions linked to oxidoreductase reactions.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a nucleoside triphosphate (GO:0106196)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic anions linked to the hydrolysis of a nucleoside triphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic anions linked to the hydrolysis of a diphosphate (GO:0106197)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of inorganic anions llinked to the hydrolysis of a diphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on inorganic anions linked to a decarboxylation reaction (GO:0106198)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of an inorganic anion linked to a decarboxylation reaction.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on amino acids and peptides linked to oxidoreductase reactions (GO:0106199)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to oxidoreductase reactions.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.
obsolete translocase activity acting on amio acids and peptides linked to the hydrolysis of a nucleoside triphosphate (GO:0106200)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the translocation of amino acids and peptides linked to the hydrolysis of a nucleoside triphosphate.
Comment: This term was made obsolete because the concept of using the non-4 digit EC classes as parent terms for the transporter branch of the onotolgy was consided confusing.