LiteFold/GO huggingface dataset:
ciliary pocket (GO:0020016)
Namespace: cellular_component
Definition: Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.
Synonyms: cilial pocket; cilium pocket; flagellar pocket
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.
ciliary pocket membrane (GO:0020018)
Namespace: cellular_component
Definition: That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).
Synonyms: cilial pocket membrane; cilium pocket membrane; flagellar pocket membrane
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is mostly 'flagellar', but the primary term name reflects the cilium parentage.
food vacuole (GO:0020020)
Namespace: cellular_component
Definition: Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.
Synonyms: digestive vacuole
acidocalcisome (GO:0020022)
Namespace: cellular_component
Definition: An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
Synonyms: metachromatic granule; polyphosphate vacuole; volutin granule
kinetoplast (GO:0020023)
Namespace: cellular_component
Definition: A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
subpellicular microtubule (GO:0020025)
Namespace: cellular_component
Definition: Singlet microtubule that lie underneath the inner membrane pellicle complex and emanate from the basal ring of the conoid.
apicomplexan dense granule (GO:0020026)
Namespace: cellular_component
Definition: Electron-dense organelle with a granular internal matrix found in a apicomplexan parasite; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.
Synonyms: dense body
hemoglobin metabolic process (GO:0020027)
Namespace: biological_process
Definition: The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
Synonyms: haemoglobin metabolic process; haemoglobin metabolism; hemoglobin metabolism
endocytic hemoglobin import into cell (GO:0020028)
Namespace: biological_process
Definition: The directed movement of hemoglobin into a cell by receptor-mediated endocytosis.
Synonyms: endocytic hemoglobin import; haemoglobin uptake; hemoglobin uptake
infected host cell surface knob (GO:0020030)
Namespace: cellular_component
Definition: Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.
polar ring of apical complex (GO:0020031)
Namespace: cellular_component
Definition: An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.
Synonyms: anterior polar ring of apical complex; upper polar ring of apical complex
basal ring of apical complex (GO:0020032)
Namespace: cellular_component
Definition: An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.
Synonyms: lower polar ring of apical complex; posterior polar ring of apical complex; preconoidal ring of apical complex
antigenic variation (GO:0020033)
Namespace: biological_process
Definition: A process by which a symbiont evades the host adaptive immune response by changing antigenic determinants on the symbiont surface that are exposed to host antibodies.
Synonyms: surface antigen variation
adhesion of symbiont to microvasculature (GO:0020035)
Namespace: biological_process
Definition: The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.
Synonyms: cytoadherence to microvasculature, mediated by parasite protein; cytoadherence to microvasculature, mediated by symbiont protein; heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein; parasite-protein-mediated cytoadherence to microvasculature; symbiont-protein-mediated cytoadherence to microvasculature
Maurer's cleft (GO:0020036)
Namespace: cellular_component
Definition: A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.
Synonyms: Maurers cleft
heme binding (GO:0020037)
Namespace: molecular_function
Definition: Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
Synonyms: haem binding
subpellicular network (GO:0020038)
Namespace: cellular_component
Definition: A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.
pellicle (GO:0020039)
Namespace: cellular_component
Definition: The structure enclosing certain parasite cells such as certain apicomplexa and Euglenozoa; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.
prechordal plate formation (GO:0021501)
Namespace: biological_process
Definition: The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.
neural fold elevation formation (GO:0021502)
Namespace: biological_process
Definition: The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.
neural fold bending (GO:0021503)
Namespace: biological_process
Definition: The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
neural fold hinge point formation (GO:0021504)
Namespace: biological_process
Definition: The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.
Synonyms: neural fold furrowing
neural fold folding (GO:0021505)
Namespace: biological_process
Definition: The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.
anterior neuropore closure (GO:0021506)
Namespace: biological_process
Definition: The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.
posterior neuropore closure (GO:0021507)
Namespace: biological_process
Definition: The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.
floor plate formation (GO:0021508)
Namespace: biological_process
Definition: The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.
roof plate formation (GO:0021509)
Namespace: biological_process
Definition: The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.
spinal cord development (GO:0021510)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
spinal cord patterning (GO:0021511)
Namespace: biological_process
Definition: The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.
spinal cord anterior/posterior patterning (GO:0021512)
Namespace: biological_process
Definition: The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.
Synonyms: spinal cord anterior-posterior patterning; spinal cord rostrocaudal patterning
spinal cord dorsal/ventral patterning (GO:0021513)
Namespace: biological_process
Definition: The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
Synonyms: spinal cord dorsal-ventral patterning; spinal cord dorsoventral patterning
dorsal spinal cord development (GO:0021516)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.
ventral spinal cord development (GO:0021517)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.
spinal cord commissural neuron specification (GO:0021518)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.
spinal cord association neuron specification (GO:0021519)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.
spinal cord motor neuron cell fate specification (GO:0021520)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
ventral spinal cord interneuron specification (GO:0021521)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
spinal cord motor neuron differentiation (GO:0021522)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
somatic motor neuron differentiation (GO:0021523)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
visceral motor neuron differentiation (GO:0021524)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
lateral motor column neuron differentiation (GO:0021525)
Namespace: biological_process
Definition: The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.
medial motor column neuron differentiation (GO:0021526)
Namespace: biological_process
Definition: The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
spinal cord association neuron differentiation (GO:0021527)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms: spinal cord dorsal interneuron differentiation
commissural neuron differentiation in spinal cord (GO:0021528)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
spinal cord oligodendrocyte cell fate specification (GO:0021530)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.
spinal cord radial glial cell differentiation (GO:0021531)
Namespace: biological_process
Definition: The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Synonyms: radial glial cell differentiation in spinal cord
neural tube patterning (GO:0021532)
Namespace: biological_process
Definition: The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.
cell differentiation in hindbrain (GO:0021533)
Namespace: biological_process
Definition: The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
cell proliferation in hindbrain (GO:0021534)
Namespace: biological_process
Definition: The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
cell migration in hindbrain (GO:0021535)
Namespace: biological_process
Definition: The orderly movement of a cell that will reside in the hindbrain.
diencephalon development (GO:0021536)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
telencephalon development (GO:0021537)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
Synonyms: cerebrum development
epithalamus development (GO:0021538)
Namespace: biological_process
Definition: The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.
subthalamus development (GO:0021539)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.
Synonyms: ventral thalamus development
dentate gyrus development (GO:0021542)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
subpallium development (GO:0021544)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.
cranial nerve development (GO:0021545)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
rhombomere development (GO:0021546)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
midbrain-hindbrain boundary initiation (GO:0021547)
Namespace: biological_process
Definition: The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms: isthmus biosynthesis; isthmus formation; MHB biosynthesis; MHB formation; midbrain-hindbrain boundary biosynthesis; midbrain-hindbrain boundary formation
cerebellum development (GO:0021549)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
medulla oblongata development (GO:0021550)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
Synonyms: medulla development; myelencephalon development
central nervous system morphogenesis (GO:0021551)
Namespace: biological_process
Definition: The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
midbrain-hindbrain boundary structural organization (GO:0021552)
Namespace: biological_process
Definition: The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms: isthmus structural organization; MHB structural organization; midbrain-hindbrain boundary structural organisation
olfactory nerve development (GO:0021553)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
Synonyms: CN 1 development; cranial nerve 1 development; cranial nerve I development
optic nerve development (GO:0021554)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
Synonyms: CN II development; cranial nerve 2 development; cranial nerve II development
midbrain-hindbrain boundary morphogenesis (GO:0021555)
Namespace: biological_process
Definition: The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms: isthmus morphogenesis; MHB morphogenesis