LiteFold/GO huggingface dataset:
3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114)
Namespace: molecular_function
Definition: Catalysis of the reaction: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate.
Synonyms: 3', 5'-cyclic nucleoside monophosphate phosphodiesterase activity; 3',5' cyclic-nucleotide phosphodiesterase activity; 3',5'-cyclic-nucleotide 5'-nucleotidohydrolase activity; 3',5'-cyclonucleotide phosphodiesterase activity; 3',5'-nucleotide phosphodiesterase activity; 3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase activity; cyclic 3',5'-mononucleotide phosphodiesterase activity; cyclic 3',5'-nucleotide phosphodiesterase activity; cyclic 3',5'-phosphodiesterase activity; cyclic 3',5-nucleotide monophosphate phosphodiesterase activity; cyclic AMP phosphodiesterase activity; cyclic nucleotide phosphodiesterase activity; cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP) activity; nucleoside 3',5'-cyclic phosphate diesterase activity; nucleoside-3',5-monophosphate phosphodiesterase activity; PDE
3',5'-cyclic-AMP phosphodiesterase activity (GO:0004115)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3',5'-cyclic AMP + H2O = AMP + H+.
Synonyms: 3',5' cAMP-specific phosphodiesterase activity; 3',5'-cAMP-specific phosphodiesterase activity; 3',5'-cyclic-AMP-specific phosphodiesterase activity; adenosine 3',5'-cyclophosphate-specific phosphodiesterase activity; cAMP-specific phosphodiesterase activity; cyclic AMP-specific phosphodiesterase activity
calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity (GO:0004117)
Namespace: molecular_function
Definition: Catalysis of the reactions: 3',5'-cyclic AMP + H2O = AMP + H+ and 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
Synonyms: calmodulin-activated cyclic-nucleotide dual specificity phosphodiesterase activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity
3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity (GO:0004118)
Namespace: molecular_function
Definition: Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.
Comment: cGMP-stimulated cyclic-nucleotide phosphodiesterase activity
3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity (GO:0004119)
Namespace: molecular_function
Definition: Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.
Comment: cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
obsolete photoreceptor cyclic-nucleotide phosphodiesterase activity (GO:0004120)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.
Comment: The reason for obsoletion is that this term represents a gene product.
obsolete cystathionine beta-lyase activity (GO:0004121)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
Comment: The reason for obsoletion is that this term is equivalent to GO:0047804 cysteine-S-conjugate beta-lyase activity.
cystathionine beta-synthase activity (GO:0004122)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
Synonyms: beta-thionase activity; L-serine hydro-lyase (adding homocysteine); L-serine hydro-lyase (adding homocysteine; L-cystathionine-forming); methylcysteine synthase activity; serine sulfhydrase activity; serine sulfhydrylase activity
cystathionine gamma-lyase activity (GO:0004123)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
Synonyms: gamma-cystathionase activity; homoserine deaminase activity; homoserine deaminase-cystathionase activity; homoserine dehydratase activity; L-cystathionine cysteine-lyase (deaminating); L-cystathionine cysteine-lyase (deaminating; 2-oxobutanoate-forming)
cysteine synthase activity (GO:0004124)
Namespace: molecular_function
Definition: Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
Synonyms: 3-O-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity; acetylserine sulfhydrylase activity; cysteine synthase activity, acting on O-acetyl-L-serine; cysteine synthetase activity; O(3)-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide) activity; O-acetyl-L-serine sulfhydrylase activity; O-acetyl-L-serine sulfohydrolase activity; O-acetylserine (thiol)-lyase A activity; O-acetylserine (thiol)-lyase activity; O-acetylserine sulfhydrylase activity; O3-acetyl-L-serine acetate-lyase (adding hydrogen-sulfide); O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase activity; OAS sulfhydrylase activity
L-seryl-tRNA(Sec) selenium transferase activity (GO:0004125)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.
Synonyms: cysteinyl-tRNA(Sec)-selenium transferase activity; cysteinyl-tRNA(Sel)-selenium transferase activity; cysteinyl-tRNA(Ser) selenium transferase activity; cysteinyl-tRNASec-selenium transferase activity; cysteinyl-tRNASel-selenium transferase activity; L-selenocysteinyl-tRNA(Sec) synthase activity; L-selenocysteinyl-tRNA(Sel) synthase activity; L-selenocysteinyl-tRNASec synthase activity; L-selenocysteinyl-tRNASel synthase activity; L-seryl-tRNASec selenium transferase activity; selenocysteine synthase activity; selenocysteinyl-tRNA(Ser) synthase activity; selenophosphate:L-seryl-tRNASec selenium transferase activity
cytidine deaminase activity (GO:0004126)
Namespace: molecular_function
Definition: Catalysis of the reaction: cytidine + H+ + H2O = uridine + NH4 and deoxycytidine + H+ + H2O = deoxyuridine + NH4+.
Synonyms: (deoxy)cytidine deaminase activity; cytidine aminohydrolase activity; cytosine nucleoside deaminase activity; deoxycytidine deaminase activity
obsolete (d)CMP kinase activity (GO:0004127)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
cytochrome-b5 reductase activity, acting on NAD(P)H (GO:0004128)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 Fe(III)-[cytochrome b5] + NAD(P)H = 2 Fe(II)-[cytochrome b5] + NAD(P)+ + H+.
cytochrome-c oxidase activity (GO:0004129)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4 Fe(II)-[cytochrome c] + O2 + 8 H+(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H+(out).
Synonyms: aa3-type cytochrome c oxidase; ba3-type cytochrome c oxidase; caa3-type cytochrome c oxidase; cbb3-type cytochrome c oxidase; complex IV (mitochondrial electron transport) activity; cytochrome a3 activity; cytochrome aa3 activity; cytochrome c oxidase activity; cytochrome oxidase activity; indophenol oxidase; indophenolase; Warburg's respiratory enzyme activity
Comment: The reduction of O2 to water is accompanied by the extrusion of four protons from the intramitochondrial compartment.
cytochrome-c peroxidase activity (GO:0004130)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 ferrocytochrome c + H2O2 = 2 ferricytochrome c + 2 H2O.
Synonyms: apocytochrome c peroxidase activity; cytochrome c peroxidase activity; cytochrome c-551 peroxidase activity; cytochrome c-H2O oxidoreductase activity; cytochrome peroxidase activity; ferrocytochrome-c:hydrogen-peroxide oxidoreductase activity; mesocytochrome c peroxidase azide; mesocytochrome c peroxidase cyanate; mesocytochrome c peroxidase cyanide
cytosine deaminase activity (GO:0004131)
Namespace: molecular_function
Definition: Catalysis of the reaction: cytosine + H2O = uracil + NH4+.
Synonyms: cytosine aminohydrolase activity; isocytosine deaminase activity
dCMP deaminase activity (GO:0004132)
Namespace: molecular_function
Definition: Catalysis of the reaction: dCMP + H2O = dUMP + NH4+.
Synonyms: dCMP aminohydrolase activity; deoxy-CMP-deaminase activity; deoxycytidine monophosphate deaminase activity; deoxycytidine-5'-monophosphate aminohydrolase activity; deoxycytidine-5'-phosphate deaminase activity; deoxycytidylate aminohydrolase activity; deoxycytidylate deaminase activity
obsolete glycogen debranching enzyme activity (GO:0004133)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the cleavage of branch points in branched glycogen polymers.
Comment: This term was obsoleted because it represents a gene product.
4-alpha-glucanotransferase activity (GO:0004134)
Namespace: molecular_function
Definition: Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
Synonyms: 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase activity; amylomaltase activity; D-enzyme activity; debranching enzyme maltodextrin glycosyltransferase activity; dextrin glycosyltransferase activity; dextrin transglycosylase activity; disproportionating enzyme activity; oligo-1,4-1,4-glucantransferase activity
amylo-alpha-1,6-glucosidase activity (GO:0004135)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.
Synonyms: amylo-1,6-glucosidase activity; amylopectin 1,6-glucosidase activity; dextrin 6-alpha-D-glucosidase activity; dextrin-1,6-glucosidase activity; glycogen phosphorylase-limit dextrin alpha-1,6-glucohydrolase activity
deoxyadenosine kinase activity (GO:0004136)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.
Synonyms: ATP:deoxyadenosine 5'-phosphotransferase activity; deoxyadenosine kinase (phosphorylating); purine-deoxyribonucleoside kinase activity
deoxycytidine kinase activity (GO:0004137)
Namespace: molecular_function
Definition: Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
Synonyms: 2'-deoxycytidine kinase activity; Ara-C kinase activity; arabinofuranosylcytosine kinase activity; deoxycytidine kinase (phosphorylating); deoxycytidine-cytidine kinase activity; NTP:deoxycytidine 5'-phosphotransferase activity
deoxyguanosine kinase activity (GO:0004138)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H+.
Synonyms: (dihydroxypropoxymethyl)guanine kinase activity; 2'-deoxyguanosine kinase activity; ATP:deoxyguanosine 5'-phosphotransferase activity; deoxyguanosine kinase (phosphorylating); NTP-deoxyguanosine 5'-phosphotransferase activity
deoxyribose-phosphate aldolase activity (GO:0004139)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
Synonyms: 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming); 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase activity; 2-deoxyribose-5-phosphate aldolase activity; deoxyriboaldolase activity; deoxyribose-5-phosphate aldolase activity; phosphodeoxyriboaldolase activity
dephospho-CoA kinase activity (GO:0004140)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+.
Synonyms: 3'-dephospho-CoA kinase activity; ATP:dephospho-CoA 3'-phosphotransferase activity; dephosphocoenzyme A kinase (phosphorylating); dephosphocoenzyme A kinase activity
dethiobiotin synthase activity (GO:0004141)
Namespace: molecular_function
Definition: Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO2 = ADP + dethiobiotin + 4 H+ + phosphate.
Synonyms: 7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming); desthiobiotin synthase activity; DTB synthetase activity
diacylglycerol cholinephosphotransferase activity (GO:0004142)
Namespace: molecular_function
Definition: Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.
Synonyms: 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase activity; 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase activity; 1-alkyl-2-acetylglycerol cholinephosphotransferase activity; alkylacylglycerol choline phosphotransferase activity; alkylacylglycerol cholinephosphotransferase activity; CDP-choline diglyceride phosphotransferase activity; CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity; cholinephosphotransferase activity; CPT; cytidine diphosphocholine glyceride transferase activity; cytidine diphosphorylcholine diglyceride transferase activity; diacylglycerol choline phosphotransferase activity; phosphocholine diacylglyceroltransferase activity; phosphorylcholine--glyceride transferase activity; sn-1,2-diacylglycerol cholinephosphotransferase activity
ATP-dependent diacylglycerol kinase activity (GO:0004143)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+.
Synonyms: DGK activity; diacylglycerol kinase activity; diacylglycerol kinase activity (ATP); diglyceride kinase activity
diacylglycerol O-acyltransferase activity (GO:0004144)
Namespace: molecular_function
Definition: Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
Synonyms: 1,2-diacylglycerol acyltransferase activity; acyl-CoA:1,2-diacylglycerol O-acyltransferase activity; diacylglycerol acyltransferase activity; diglyceride acyltransferase activity; diglyceride O-acyltransferase activity; palmitoyl-CoA-sn-1,2-diacylglycerol acyltransferase activity
diamine N-acetyltransferase activity (GO:0004145)
Namespace: molecular_function
Definition: Catalysis of the reaction: an alkane-alpha,omega-diamine + acetyl-CoA = an N-acetylalkane-alpha,omega-diamine + CoA + H+.
Synonyms: acetyl-CoA:alkane-alpha,omega-diamine N-acetyltransferase activity; acetyl-coenzyme A-1,4-diaminobutane N-acetyltransferase activity; diamine acetyltransferase activity; putrescine (diamine)-acetylating enzyme activity; putrescine acetylase activity; putrescine acetyltransferase activity; putrescine N-acetyltransferase activity; spermidine acetyltransferase activity; spermidine N(1)-acetyltransferase activity; spermidine N1-acetyltransferase activity; spermidine/spermine N1-acetyltransferase activity; spermine acetyltransferase; spermine N(1)-acetyltransferase; spermine N-acetyltransferase
dihydrofolate reductase activity (GO:0004146)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
Synonyms: 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase activity; 7,8-dihydrofolate reductase activity; DHFR; dihydrofolate reductase:thymidylate synthase activity; dihydrofolate reduction; dihydrofolic acid reductase activity; dihydrofolic reductase activity; folic acid reductase activity; folic reductase activity; NADPH-dihydrofolate reductase activity; pteridine reductase:dihydrofolate reductase activity; tetrahydrofolate dehydrogenase activity; thymidylate synthetase-dihydrofolate reductase activity
dihydrolipoyl dehydrogenase (NADH) activity (GO:0004148)
Namespace: molecular_function
Definition: Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD+ = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H+.
Synonyms: dehydrolipoate dehydrogenase activity; diaphorase activity; dihydrolipoamide dehydrogenase activity; dihydrolipoamide reduction; dihydrolipoamide:NAD+ oxidoreductase; dihydrolipoic dehydrogenase activity; dihydrolipoylprotein reduction; dihydrothioctic dehydrogenase activity; E3 component of alpha-ketoacid dehydrogenase complexes activity; glycine-cleavage system L-protein activity; L-protein activity; LDP-Glc activity; LDP-Val activity; lipoamide dehydrogenase (NADH) activity; lipoamide oxidoreductase (NADH) activity; lipoamide reductase (NADH) activity; lipoamide reductase activity; lipoate dehydrogenase activity; lipoic acid dehydrogenase activity; lipoyl dehydrogenase activity; protein-6-N-(dihydrolipoyl)lysine:NAD+ oxidoreductase; protein-N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
dihydrolipoyllysine-residue succinyltransferase activity (GO:0004149)
Namespace: molecular_function
Definition: Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA.
Synonyms: dihydrolipoamide S-succinyltransferase activity; dihydrolipoamide succinyltransferase activity; dihydrolipoic transsuccinylase activity; dihydrolipolyl transsuccinylase activity; dihydrolipoyl transsuccinylase activity; enzyme-dihydrolipoyllysine:succinyl-CoA S-succinyltransferase activity; lipoate succinyltransferase (Escherichia coli) activity; lipoate succinyltransferase activity; lipoic transsuccinylase activity; lipoyl transsuccinylase activity; succinyl-CoA:dihydrolipoamide S-succinyltransferase activity; succinyl-CoA:dihydrolipoate S-succinyltransferase activity; succinyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-succinyltransferase activity; succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase activity
dihydroneopterin aldolase activity (GO:0004150)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.
Synonyms: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase (2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-forming); 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine glycolaldehyde-lyase activity
dihydroorotase activity (GO:0004151)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate + H+.
Synonyms: (S)-dihydroorotate amidohydrolase activity; carbamoylaspartic dehydrase activity; DHOase activity; dihydroorotate hydrolase activity
dihydroorotate dehydrogenase activity (GO:0004152)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
dihydropterin deaminase activity (GO:0004153)
Namespace: molecular_function
Definition: Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH4+.
dihydropterin oxidase activity (GO:0004154)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 7,8-dihydropteridine compound + O2 = an oxidized 7,8-dihydropteridine compound + H2O2. Specific substrates and their fully oxidized products include: 7,8-dihydropteridin/pterin, 7,8-dihydrobiopterin/biopterin, 7,8-dihydroxanthopterin/xanthopterin and sepiapterin/oxidized sepiapterin.
6,7-dihydropteridine reductase activity (GO:0004155)
Namespace: molecular_function
Definition: Catalysis of the reaction: NAD(P)+ + 5,6,7,8-tetrahydropteridine = NAD(P)H + H+ + 6,7-dihydropteridine.
Synonyms: 5,6,7,8-tetrahydropteridine:NAD(P)+ oxidoreductase activity; 5,6,7,8-tetrahydropteridine:NAD(P)H+ oxidoreductase activity; 6,7-dihydropteridine:NAD(P)H oxidoreductase activity; DHPR activity; dihydropteridine (reduced nicotinamide adenine dinucleotide) reductase activity; dihydropteridine reductase (NADH) activity; dihydropteridine reductase activity; dihydropteridine reduction; NAD(P)H(2):6,7-dihydropteridine oxidoreductase activity; NAD(P)H2:6,7-dihydropteridine oxidoreductase activity; NADH-dihydropteridine reductase activity; NADPH-dihydropteridine reductase activity; NADPH-specific dihydropteridine reductase activity
dihydropteroate synthase activity (GO:0004156)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.
Synonyms: (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase activity; 7,8-dihydropteroate synthase activity; 7,8-dihydropteroate synthetase activity; 7,8-dihydropteroic acid synthetase activity; DHPS activity; dihydropteroate diphosphorylase activity; dihydropteroate pyrophosphorylase activity; dihydropteroate synthetase activity; dihydropteroic synthetase activity
dihydropyrimidinase activity (GO:0004157)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.
Synonyms: 5,6-dihydropyrimidine amidohydrolase activity; D-hydantoinase activity; hydantoin peptidase activity; hydantoinase activity; hydropyrimidine hydrase activity; pyrimidine hydrase activity
obsolete dihydroorotate oxidase activity (GO:0004158)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (S)-dihydroorotate + O2 = H2O2 + orotate.
Synonyms: (S)-dihydroorotate:oxygen oxidoreductase activity; 4,5-L-dihydroorotate:oxygen oxidoreductase activity
Comment: There appears to be no evidence for this reaction. The original EC used for this reaction was not appropriate.
dihydropyrimidine dehydrogenase (NAD+) activity (GO:0004159)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.
Synonyms: 5,6-dihydrouracil:NAD+ oxidoreductase activity; dihydrothymine dehydrogenase (NAD+) activity; dihydrouracil dehydrogenase (NAD+) activity; pyrimidine reductase activity; thymine reductase activity; uracil reductase activity
dimethylallyltranstransferase activity (GO:0004161)
Namespace: molecular_function
Definition: Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = (2E)-geranyl diphosphate + diphosphate.
Synonyms: (2E,6E)-farnesyl diphosphate synthetase activity; dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase activity; dimethylallyltransferase activity; diprenyltransferase activity; DMAPP:IPP-dimethylallyltransferase activity; geranyl diphosphate synthase activity; geranyl pyrophosphate synthase activity; geranyl pyrophosphate synthetase activity; geranyl-diphosphate synthase activity; trans-farnesyl pyrophosphate synthetase activity
Comment: Note that this is the first step in the formation of farnesyl diphosphate. The second step is 'geranyltranstransferase activity ; GO:0004337'. Consider also annotating to the biological process term 'farnesyl diphosphate biosynthetic process ; GO:0045337'.
diphosphomevalonate decarboxylase activity (GO:0004163)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.
Synonyms: 5-pyrophosphomevalonate decarboxylase activity; ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming); ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating); mevalonate 5-diphosphate decarboxylase activity; mevalonate diphosphate decarboxylase activity; mevalonate pyrophosphate decarboxylase activity; mevalonate-5-pyrophosphate decarboxylase activity; pyrophosphomevalonate decarboxylase activity; pyrophosphomevalonic acid decarboxylase activity