LiteFold/GO huggingface dataset:
negative regulation of termination of RNA polymerase II transcription (GO:0120191)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription.
Synonyms: down regulation of RNA 3'-end formation by RNA polymerase II; down regulation of RNA polymerase II transcription termination; down regulation of RNA polymerase II transcription termination factor activity; down regulation of termination of RNA polymerase II transcription; down regulation of transcription termination from Pol II promoter; down regulation of transcription termination from RNA polymerase II promoter; down-regulation of RNA 3'-end formation by RNA polymerase II; down-regulation of RNA polymerase II transcription termination; down-regulation of RNA polymerase II transcription termination factor activity; down-regulation of termination of RNA polymerase II transcription; down-regulation of transcription termination from Pol II promoter; down-regulation of transcription termination from RNA polymerase II promoter; downregulation of RNA 3'-end formation by RNA polymerase II; downregulation of RNA polymerase II transcription termination; downregulation of RNA polymerase II transcription termination factor activity; downregulation of termination of RNA polymerase II transcription; downregulation of transcription termination from Pol II promoter; downregulation of transcription termination from RNA polymerase II promoter; negative regulation of RNA 3'-end formation by RNA polymerase II; negative regulation of RNA polymerase II transcription termination; negative regulation of RNA polymerase II transcription termination factor activity; negative regulation of transcription termination from Pol II promoter; negative regulation of transcription termination from RNA polymerase II promoter; repression of RNA 3'-end formation by RNA polymerase II; repression of RNA polymerase II transcription termination; repression of RNA polymerase II transcription termination factor activity; repression of termination of RNA polymerase II transcription; repression of transcription termination from Pol II promoter; repression of transcription termination from RNA polymerase II promoter
tight junction assembly (GO:0120192)
Namespace: biological_process
Definition: A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
Synonyms: occluding cell junction assembly; occluding junction assembly
tight junction organization (GO:0120193)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
Synonyms: occluding cell junction organization; occluding junction organization
regulation of anther dehiscence (GO:0120194)
Namespace: biological_process
Definition: Any process involved in the dehiscence of an anther to release the pollen grains contained within it.
positive regulation of anther dehiscence (GO:0120195)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of anther dehiscence.
positive regulation of imaginal disc-derived wing size (GO:0120198)
Namespace: biological_process
Definition: Any process that increases the size of an imaginal disc-derived wing.
cone photoreceptor outer segment (GO:0120199)
Namespace: cellular_component
Definition: The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins.
rod photoreceptor outer segment (GO:0120200)
Namespace: cellular_component
Definition: The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins.
cone photoreceptor disc membrane (GO:0120201)
Namespace: cellular_component
Definition: Stack of disc membranes located inside a cone photoreceptor outer segment, and containing densely packed molecules of opsin photoreceptor proteins that traverse the lipid bilayer. Cone disc membranes arise as evaginations of the ciliary membrane during the development of the cone outer segment and remain contiguous with the ciliary membrane.
rod photoreceptor disc membrane (GO:0120202)
Namespace: cellular_component
Definition: Stack of disc membranes located inside a rod photoreceptor outer segment, and containing densely packed molecules of rhodopsin photoreceptor proteins that traverse the lipid bilayer. It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment.
rod photoreceptor disc lumen (GO:0120203)
Namespace: cellular_component
Definition: The volume enclosed by the membrane of a rod photoreceptor cell disc membrane.
methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity (GO:0120204)
Namespace: molecular_function
Definition: Catalysis of the reaction: methylcytosine + L-ascorbate + O2 = 5-glyceryl-methylcytosine + glyoxylate + CO2.
photoreceptor proximal connecting cilium (GO:0120205)
Namespace: cellular_component
Definition: The proximal region of the photoreceptor connecting cilium is similar to the transition zone of unspecialized primary cilia and houses several major transition zone complexes, including NPHP, MKS, and RPGR.
Synonyms: PCC; photoreceptor PCC
photoreceptor distal connecting cilium (GO:0120206)
Namespace: cellular_component
Definition: The distal region of the photoreceptor connecting cilium is structurally unique to the photoreceptor and is maintained by retina-specific protein, SPATA7, and its interacting partners RPGR and RPGRIP1. It is essential for photoreceptor sensory cilium stability.
Synonyms: DCC; photoreceptor DCC
endocytosis, site selection (GO:0120207)
Namespace: biological_process
Definition: The process of selecting and or marking the position where endocytosis will occur.
telodendria (GO:0120208)
Namespace: cellular_component
Definition: Telodendria are projections that originate from the axon pedicle and form gap junctions with other neurons.
cone telodendria (GO:0120209)
Namespace: cellular_component
Definition: Cone telodendria are projections that originate from the cone pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.
proacrosomal vesicle fusion (GO:0120211)
Namespace: biological_process
Definition: Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.
regulation of histidine biosynthetic process (GO:0120213)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of histidine biosynthetic process.
Synonyms: regulation of histidine anabolism; regulation of histidine biosynthesis; regulation of histidine formation; regulation of histidine synthesis
negative regulation of histidine biosynthetic process (GO:0120214)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of histidine biosynthetic process.
Synonyms: down regulation of histidine anabolism; down regulation of histidine biosynthesis; down regulation of histidine biosynthetic process; down regulation of histidine formation; down regulation of histidine synthesis; down-regulation of histidine anabolism; down-regulation of histidine biosynthesis; down-regulation of histidine biosynthetic process; down-regulation of histidine formation; down-regulation of histidine synthesis; downregulation of histidine anabolism; downregulation of histidine biosynthesis; downregulation of histidine biosynthetic process; downregulation of histidine formation; downregulation of histidine synthesis; inhibition of histidine anabolism; inhibition of histidine biosynthesis; inhibition of histidine biosynthetic process; inhibition of histidine formation; inhibition of histidine synthesis; negative regulation of histidine anabolism; negative regulation of histidine biosynthesis; negative regulation of histidine formation; negative regulation of histidine synthesis
positive regulation of histidine biosynthetic process (GO:0120215)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.
Synonyms: activation of histidine anabolism; activation of histidine biosynthesis; activation of histidine biosynthetic process; activation of histidine formation; activation of histidine synthesis; positive regulation of histidine anabolism; positive regulation of histidine biosynthesis; positive regulation of histidine formation; positive regulation of histidine synthesis; up regulation of histidine anabolism; up regulation of histidine biosynthesis; up regulation of histidine biosynthetic process; up regulation of histidine formation; up regulation of histidine synthesis; up-regulation of histidine anabolism; up-regulation of histidine biosynthesis; up-regulation of histidine biosynthetic process; up-regulation of histidine formation; up-regulation of histidine synthesis; upregulation of histidine anabolism; upregulation of histidine biosynthesis; upregulation of histidine biosynthetic process; upregulation of histidine formation; upregulation of histidine synthesis
matrilin complex (GO:0120216)
Namespace: cellular_component
Definition: A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. Exists as an obligate homotrimer.
Synonyms: matrilin family complex; matrilin-1 complex; matrilin-2 complex; matrilin-3 complex; matrilin-4 complex
DNA gyrase complex (GO:0120217)
Namespace: cellular_component
Definition: A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB).
Synonyms: topoisomerase II complex
host interaction involved in quorum sensing (GO:0120218)
Namespace: biological_process
Definition: A quorum sensing process that is modulated by some interaction with a host cell or organism.
subapical part of cell (GO:0120219)
Namespace: cellular_component
Definition: The region of a polarized cell that is just below the apical region. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue so the subapical region is further from the exposed surface and closer to the basal lamina.
Synonyms: subapical region of cell
basal body patch (GO:0120220)
Namespace: cellular_component
Definition: The region in the apical portion of multiciliated epithelial cells where the ciliary basal bodies cluster.
Synonyms: centriolar patch
regulation of blastocyst development (GO:0120222)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of blastocyst development.
larynx morphogenesis (GO:0120223)
Namespace: biological_process
Definition: The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.
Synonyms: laryngeal morphogenesis
larynx development (GO:0120224)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.
coenzyme A binding (GO:0120225)
Namespace: molecular_function
Definition: Binding to coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms: CoA binding
succinyl-CoA binding (GO:0120226)
Namespace: molecular_function
Definition: Binding to succinyl-CoA, an omega-carboxyacyl-CoA having succinoyl as the S-acyl component.
Synonyms: succinyl-coenzyme A binding
acyl-CoA binding (GO:0120227)
Namespace: molecular_function
Definition: Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.
Synonyms: acyl binding; acyl-coenzyme A binding
protein localization to motile cilium (GO:0120229)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within a motile cilium.
Synonyms: protein localization to nonmotile primary cilium
recombinase activator activity (GO:0120230)
Namespace: molecular_function
Definition: Binds to and increases the activity of a recombinase.
DNA recombinase auxiliary factor complex (GO:0120231)
Namespace: cellular_component
Definition: A protein complex that binds to a recombinase and incrseases its activity.
Synonyms: DNA recombinase accessory factor complex; DNA recombinase activator complex
prenyl-FMNH2 biosynthetic process (GO:0120232)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.
Synonyms: prenyl-FMNH2 anabolism; prenyl-FMNH2 biosynthesis; prenyl-FMNH2 formation; prenyl-FMNH2 synthesis; prenylated FMNH2 anabolism; prenylated FMNH2 biosynthesis; prenylated FMNH2 biosynthetic process; prenylated FMNH2 formation; prenylated FMNH2 synthesis
prenyl-FMNH2 binding (GO:0120233)
Namespace: molecular_function
Definition: Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.
Synonyms: prenylated FMNH2 binding
stereocilium coat (GO:0120234)
Namespace: cellular_component
Definition: A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle.
Synonyms: auditory hair cell glycocalyx; stereocilium glycocalyx
regulation of post-translational protein targeting to membrane, translocation (GO:0120235)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.
Synonyms: regulation of N-terminal signal peptide-independent translocation into the ER; regulation of posttranslational endoplasmic reticulum membrane protein translocation; regulation of posttranslational protein targeting to membrane, translocation; regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation
negative regulation of post-translational protein targeting to membrane, translocation (GO:0120236)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of posttranslational protein translocation through the ER membrane.
Synonyms: negative regulation of N-terminal signal peptide-independent translocation into the ER; negative regulation of posttranslational endoplasmic reticulum membrane protein translocation; negative regulation of posttranslational protein targeting to membrane, translocation; negative regulation of SRP-independent endoplasmic reticulum protein-membrane targeting, translocation
obsolete terminal acetylenic compound biosynthetic process (GO:0120237)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
Synonyms: terminal alkyne substituted compound anabolic process; terminal alkyne substituted compound anabolism; terminal alkyne substituted compound biosynthesis; terminal alkyne substituted compound biosynthetic process; terminal alkyne substituted compound synthesis
Comment: This term was obsoleted because it is an unnecessary grouping class.
vascular endothelial glycocalyx (GO:0120239)
Namespace: cellular_component
Definition: The carbohydrate-rich layer lining the vascular endothelium connected to the endothelium through a variety of molecules, mainly proteoglycans and glycoproteins. These form a network in which soluble molecules, either plasma- or endothelium-derived, are incorporated.
Synonyms: endothelial glycocalyx
platelet glycocalyx (GO:0120240)
Namespace: cellular_component
Definition: The carbohydrate rich layer at the outermost periphery of a platelet.
2-iminobutanoate/2-iminopropanoate deaminase activity (GO:0120241)
Namespace: molecular_function
Definition: Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.
Synonyms: 2-iminobutanoate deaminase; 2-iminopropanoate deaminase; enamine/imine deaminase; imine intermediate deaminase activity
Comment: This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17. The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates (from EC:3.5.99.10).
2-iminobutanoate deaminase activity (GO:0120242)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-iminobutanoate + H2O = 2-oxobutanoate + NH4+.
Synonyms: 2-iminobutanoate/2-iminopropanoate deaminase
2-iminopropanoate deaminase activity (GO:0120243)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-iminopropanoate + H2O = NH4+ + pyruvate.
Synonyms: 2-iminobutanoate/2-iminopropanoate deaminase
obsolete terminal acetylenic compound metabolic process (GO:0120244)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving a terminal acetylenic compound, involving a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
Synonyms: terminal alkyne substituted compound metabolic process; terminal alkyne substituted compound metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete acetylenic compound metabolic process (GO:0120246)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
Synonyms: alkyne substituted compound metabolic process; alkyne substituted compound metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete acetylenic compound biosynthetic process (GO:0120247)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
Synonyms: alkyne substituted compound anabolic process; alkyne substituted compound anabolism; alkyne substituted compound biosynthesis; alkyne substituted compound biosynthetic process; alkyne substituted compound synthesis
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete acetylenic compound catabolic process (GO:0120248)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).
Synonyms: alkyne substituted compound breakdown; alkyne substituted compound catabolic process; alkyne substituted compound catabolism; alkyne substituted compound degradation
Comment: This term was obsoleted because it is an unnecessary grouping class.
lateral wall of outer hair cell (GO:0120249)
Namespace: cellular_component
Definition: The lateral wall of an outer hair cell (OHC) is a unique trilaminate composite consisting of the plasma membrane, an underlying cytoskeletal network containing an actin-spectrin cortical lattice, and an adjacent system of circumferential lamellar organelles known as the subsurface cisternae.
Synonyms: lateral wall of OHC; OHC lateral wall; outer hair cell lateral wall
fatty acid omega-hydroxylase activity (GO:0120250)
Namespace: molecular_function
Definition: Catalysis of the reaction: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
Synonyms: omega-hydroxylase activity
hydrocarbon biosynthetic process (GO:0120251)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a hydrocarbon, a compound consisting of carbon and hydrogen only.
Synonyms: hydrocarbon anabolism; hydrocarbon biosynthesis; hydrocarbon formation; hydrocarbon synthesis
hydrocarbon metabolic process (GO:0120252)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.
Synonyms: hydrocarbon metabolism
hydrocarbon catabolic process (GO:0120253)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.
Synonyms: hydrocarbon breakdown; hydrocarbon catabolism; hydrocarbon degradation
olefinic compound biosynthetic process (GO:0120255)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms: alkene substituted compound anabolic process; alkene substituted compound anabolism; alkene substituted compound biosynthesis; alkene substituted compound biosynthetic process; alkene substituted compound synthesis
olefinic compound catabolic process (GO:0120256)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms: alkene substituted compound breakdown; alkene substituted compound catabolic process; alkene substituted compound catabolism; alkene substituted compound degradation
peptidyl-threonine acetylation (GO:0120257)
Namespace: biological_process
Definition: The acetylation of peptidyl-threonine.
peptidyl-threonine O-acetylation (GO:0120258)
Namespace: biological_process
Definition: The acetylation of peptidyl-threonine to form peptidyl-O-acetyl-L-threonine.
7SK snRNP (GO:0120259)
Namespace: cellular_component
Definition: A ribonucleoprotein complex that contains the 7SK snRNA. The 7SK snRNP plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb.
Synonyms: snRNP 7SK
ciliary microtubule quartet (GO:0120260)
Namespace: cellular_component
Definition: A set of four specialized microtubules that originates from the basal bodies and wraps around the ciliary pocket membrane, likely supporting its distinct flask shape.
Synonyms: ciliary MtQ
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane.