LiteFold/GO huggingface dataset:
obsolete negative regulation of cellular carbohydrate metabolic process (GO:0010677)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
Comment: This term was obsoleted because it is not different from its parent, negative regulation of carbohydrate metabolic process ; GO:0045912.
obsolete negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated (GO:0010678)
Namespace: biological_process
Definition: OBSOLETE. Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription.
Synonyms: negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent; negative regulation of cellular carbohydrate metabolic process by repression of transcription; negative regulation of cellular carbohydrate metabolic process by transcriptional repression
Comment: This term was obsoleted because it is represents a GO-CAM model.
obsolete cinnamic acid biosynthetic process involved in salicylic acid metabolism (GO:0010679)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.
Comment: This term was obsoleted because it does not represent a specific pathway.
obsolete cinnamic acid biosynthetic process involved in coumarin metabolism (GO:0010680)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.
Comment: This term was obsoleted because it does not represent a specific pathway.
obsolete cinnamic acid biosynthetic process involved in stilbene metabolism (GO:0010681)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.
Comment: This term was obsoleted because it does not represent a specific pathway.
obsolete cinnamic acid biosynthetic process involved in flavonoid metabolism (GO:0010682)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.
Comment: This term was obsoleted because it does not represent a specific pathway.
obsolete tricyclic triterpenoid metabolic process (GO:0010683)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
Synonyms: tricyclic triterpenoid metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
tricyclic triterpenoid catabolic process (GO:0010684)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
Synonyms: tricyclic triterpenoid catabolism
obsolete tetracyclic triterpenoid metabolic process (GO:0010685)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
Synonyms: tetracyclic triterpenoid metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
tetracyclic triterpenoid biosynthetic process (GO:0010686)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
Synonyms: tetracyclic triterpenoid biosynthesis
negative regulation of ribosomal protein gene transcription by RNA polymerase II (GO:0010688)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.
Synonyms: negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus (GO:0010689)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress (GO:0010690)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.
negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels (GO:0010691)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
obsolete regulation of alkaline phosphatase activity (GO:0010692)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
regulation of mitotic spindle pole body separation (GO:0010695)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
Synonyms: regulation of SPB separation
positive regulation of mitotic spindle pole body separation (GO:0010696)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
Synonyms: positive regulation of SPB separation
negative regulation of mitotic spindle pole body separation (GO:0010697)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
Synonyms: negative regulation of SPB separation
acetyltransferase activator activity (GO:0010698)
Namespace: molecular_function
Definition: Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.
Synonyms: acetyltransferase stimulator activity
negative regulation of norepinephrine secretion (GO:0010700)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.
positive regulation of norepinephrine secretion (GO:0010701)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.
obsolete negative regulation of histolysis (GO:0010703)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of the breakdown of tissues; usually, if not always, accompanied by cell death.
Synonyms: down regulation of histolysis; down-regulation of histolysis; downregulation of histolysis; inhibition of histolysis
Comment: This term was made obsolete because it refers to a phenotype. When death of a cell or tissue is a result of a true biological process, this should be captured using 'programmed cell death' or one of its descendants.
obsolete meiotic DNA double-strand break processing involved in meiotic gene conversion (GO:0010704)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (GO:0010705)
Namespace: biological_process
Definition: The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.
obsolete ganglioside biosynthetic process via lactosylceramide (GO:0010706)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
Synonyms: biosynthesis of lactosylceramide precursor to ganglioside; ganglioside biosynthesis via lactosylceramide biosynthesis; lactosylceramide biosynthesis leading to ganglioside; lactosylceramide biosynthetic process leading to ganglioside
Comment: This term was obsoleted because it represents the same process as ganglioside biosynthetic process ; GO:0001574.
obsolete globoside biosynthetic process via lactosylceramide (GO:0010707)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
Synonyms: biosynthesis of lactosylceramide precursor to globoside; globoside biosynthesis via lactosylceramide biosynthesis; lactosylceramide biosynthesis leading to globoside; lactosylceramide biosynthetic process leading to globoside
Comment: This term was obsoleted because it represents the same process as globoside biosynthetic process ; GO:0001576.
heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing (GO:0010709)
Namespace: biological_process
Definition: The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.
regulation of collagen catabolic process (GO:0010710)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
Synonyms: regulation of collagen breakdown; regulation of collagen catabolism; regulation of collagen degradation
negative regulation of collagen catabolic process (GO:0010711)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
Synonyms: down regulation of collagen catabolic process; down-regulation of collagen catabolic process; downregulation of collagen catabolic process; inhibition of collagen catabolic process; negative regulation of collagen breakdown; negative regulation of collagen catabolism; negative regulation of collagen degradation
negative regulation of collagen metabolic process (GO:0010713)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
positive regulation of collagen metabolic process (GO:0010714)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
Synonyms: positive regulation of collagen metabolism
regulation of extracellular matrix disassembly (GO:0010715)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
Synonyms: regulation of extracellular matrix breakdown; regulation of extracellular matrix degradation
negative regulation of extracellular matrix disassembly (GO:0010716)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
Synonyms: down regulation of extracellular matrix disassembly; down-regulation of extracellular matrix disassembly; downregulation of extracellular matrix disassembly; inhibition of extracellular matrix disassembly; negative regulation of extracellular matrix breakdown; negative regulation of extracellular matrix degradation
positive regulation of epithelial to mesenchymal transition (GO:0010718)
Namespace: biological_process
Definition: Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
negative regulation of epithelial to mesenchymal transition (GO:0010719)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
positive regulation of cell development (GO:0010720)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
negative regulation of cell development (GO:0010721)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
obsolete regulation of ferrochelatase activity (GO:0010722)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.
Comment: This term was obsoleted because it represents a molecular function.
regulation of definitive erythrocyte differentiation (GO:0010724)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
Synonyms: regulation of definitive erythropoiesis; regulation of definitive RBC differentiation; regulation of definitive red blood cell differentiation
regulation of primitive erythrocyte differentiation (GO:0010725)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.
Synonyms: regulation of primitive erythropoeisis; regulation of primitive RBC differentiation; regulation of primitive red blood cell differentiation
negative regulation of hydrogen peroxide metabolic process (GO:0010727)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
Synonyms: negative regulation of hydrogen peroxide metabolism
regulation of hydrogen peroxide biosynthetic process (GO:0010728)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms: regulation of hydrogen peroxide biosynthesis
positive regulation of hydrogen peroxide biosynthetic process (GO:0010729)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms: positive regulation of hydrogen peroxide biosynthesis
negative regulation of hydrogen peroxide biosynthetic process (GO:0010730)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms: negative regulation of hydrogen peroxide biosynthesis
protein glutathionylation (GO:0010731)
Namespace: biological_process
Definition: The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
Synonyms: protein amino acid glutathionylation
regulation of protein glutathionylation (GO:0010732)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
Synonyms: regulation of protein amino acid glutathionylation
positive regulation of protein glutathionylation (GO:0010733)
Namespace: biological_process
Definition: Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
Synonyms: positive regulation of protein amino acid glutathionylation
negative regulation of protein glutathionylation (GO:0010734)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
Synonyms: negative regulation of protein amino acid glutathionylation
obsolete positive regulation of transcription via serum response element binding (GO:0010735)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
Comment: This term was obsoleted because it represents a molecular function.
serum response element binding (GO:0010736)
Namespace: molecular_function
Definition: Binding to a serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
obsolete protein kinase A signaling (GO:0010737)
Namespace: biological_process
Definition: OBSOLETE. An intracellular signaling cassette that starts with the activation of protein kinase A (PKA), and ends with the regulation of a downstream cellular process, e.g. transcription. The PKA catalytic subunit (PKA-C) is normally present in a complex with its regulatory subunit, PKA-R. The inhibitory action of PKA-R is released upon cAMP binding, which results in the activation of PKA-C.
Synonyms: PKA signaling cascade; protein kinase A signal transduction; protein kinase A signaling cascade; protein kinase A signalling cascade
Comment: This term was obsoleted because it does not represent a specific pathway. Consider cAMP/PKA signal transduction ; GO:0141156 or adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0007189.
obsolete positive regulation of protein kinase A signaling (GO:0010739)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
Synonyms: positive regulation of PKA signaling cascade; positive regulation of protein kinase A signaling cascade; positive regulation of protein kinase A signalling cascade
Comment: This term was obsoleted because it does not represent the regulation of a specific pathway. Consider positive regulation of cAMP/PKA signal transduction ; GO:0141163 or positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway ; GO:0106071.
regulation of macrophage derived foam cell differentiation (GO:0010743)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
positive regulation of macrophage derived foam cell differentiation (GO:0010744)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
negative regulation of macrophage derived foam cell differentiation (GO:0010745)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.