LiteFold/GO huggingface dataset:
regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion (GO:0010969)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
transport along microtubule (GO:0010970)
Namespace: biological_process
Definition: The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
Synonyms: establishment of localization by movement along microtubule; microtubule-based transport; movement along microtubule
positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)
Namespace: biological_process
Definition: Any signaling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
Synonyms: positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle; positive regulation of mitotic entry
negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)
Namespace: biological_process
Definition: Any signaling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
Synonyms: negative regulation of mitotic entry
positive regulation of division septum assembly (GO:0010973)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
Synonyms: positive regulation of division septum formation; positive regulation of division septum formation involved in cell cycle cytokinesis; upregulation of mitotic division septum assembly
negative regulation of division septum assembly (GO:0010974)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
Synonyms: inhibition of division septum assembly involved in cell cycle cytokinesis; negative regulation of division septum formation
regulation of neuron projection development (GO:0010975)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
Synonyms: regulation of neurite biosynthesis; regulation of neurite development; regulation of neurite formation; regulation of neurite growth
positive regulation of neuron projection development (GO:0010976)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
Synonyms: positive regulation of neurite biosynthesis; positive regulation of neurite development; positive regulation of neurite formation; positive regulation of neurite growth
obsolete gene silencing involved in chronological cell aging (GO:0010978)
Namespace: biological_process
Definition: OBSOLETE. Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.
Comment: This term was obsoleted because it represent an assay - how long the cell lives -, not a true biological process.
obsolete regulation of vitamin D 24-hydroxylase activity (GO:0010979)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of vitamin D 24-hydroxylase activity (GO:0010980)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
regulation of cell wall macromolecule metabolic process (GO:0010981)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
regulation of high-density lipoprotein particle clearance (GO:0010982)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
positive regulation of high-density lipoprotein particle clearance (GO:0010983)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
regulation of lipoprotein particle clearance (GO:0010984)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
negative regulation of lipoprotein particle clearance (GO:0010985)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
positive regulation of lipoprotein particle clearance (GO:0010986)
Namespace: biological_process
Definition: Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
negative regulation of high-density lipoprotein particle clearance (GO:0010987)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
regulation of low-density lipoprotein particle clearance (GO:0010988)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
negative regulation of low-density lipoprotein particle clearance (GO:0010989)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
obsolete regulation of SMAD protein complex assembly (GO:0010990)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
Comment: This term was obsoleted because it represents a readout for regulation of SMAD protein signal transduction ; GO:0060390.
obsolete negative regulation of SMAD protein complex assembly (GO:0010991)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
Comment: This term was obsoleted because it represents a readout for negative regulation of SMAD protein signal transduction ; GO:0060392.
ubiquitin recycling (GO:0010992)
Namespace: biological_process
Definition: Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell by recycling ubiquitin from proteasome-bound ubiquitinated intermediates.
Synonyms: regulation of ubiquitin homeostasis; ubiquitin homeostasis
free ubiquitin chain polymerization (GO:0010994)
Namespace: biological_process
Definition: The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.
free ubiquitin chain depolymerization (GO:0010995)
Namespace: biological_process
Definition: The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.
response to auditory stimulus (GO:0010996)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
Synonyms: response to sound; response to sound stimulus
anaphase-promoting complex binding (GO:0010997)
Namespace: molecular_function
Definition: Binding to an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.
Synonyms: APC binding
regulation of translational initiation by eIF2 alpha phosphorylation (GO:0010998)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
Synonyms: eIF2 alpha phosphorylation in response to stress; regulation of translational initiation by eIF2 alpha phosphorylation in response to stress
Comment: Consider also annotating to 'eukaryotic translation initiation factor 2alpha kinase activity ; GO:0004694'.
regulation of eIF2 alpha phosphorylation by heme (GO:0010999)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.
replication fork arrest at mating type locus (GO:0011000)
Namespace: biological_process
Definition: A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.
programmed cell death (GO:0012501)
Namespace: biological_process
Definition: A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
Synonyms: caspase-independent apoptosis; caspase-independent cell death; non-apoptotic programmed cell death; nonapoptotic programmed cell death; PCD; RCD; regulated cell death
Comment: Note that this term should be used to annotate gene products in the organism undergoing the programmed cell death. To annotate genes in another organism whose products modulate programmed cell death in a host organism, consider the term 'modulation by symbiont of host programmed cell death ; GO:0052040'. Also, note that 'programmed cell death ; GO:0012501' should be used to refer to instances of caspase-independent cell death mechanisms, in the absence of further indications on the process taking place. At present, caspase-independent cell death is not yet represented in GO due to the lack of consensus and in-depth research on the topic. 'programmed cell death ; GO:0012501' may also be used to annotate gene products in taxa where apoptosis as defined in GO:0006915 does not occur, such as plants. You may also consider these specific children: GO:0097468 'programmed cell death in response to reactive oxygen species' (with descendants GO:0010421 'hydrogen peroxide-mediated programmed cell death' and GO:0010343 'singlet oxygen-mediated programmed cell death'), and GO:0009626 'plant-type hypersensitive response' and its children.
induction of programmed cell death (GO:0012502)
Namespace: biological_process
Definition: A process which directly activates any of the steps required for programmed cell death.
Synonyms: induction of non-apoptotic programmed cell death; induction of nonapoptotic programmed cell death
vesicle membrane (GO:0012506)
Namespace: cellular_component
Definition: The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
ER to Golgi transport vesicle membrane (GO:0012507)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
Synonyms: COPII coated vesicle membrane; endoplasmic reticulum to Golgi transport vesicle membrane; endoplasmic reticulum-Golgi transport vesicle membrane; ER to Golgi constitutive secretory pathway transport vesicle membrane; ER-Golgi transport vesicle membrane
Golgi to ER transport vesicle membrane (GO:0012508)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.
Synonyms: Golgi to endoplasmic reticulum transport vesicle membrane; Golgi to ER constitutive secretory pathway transport vesicle membrane; Golgi-endoplasmic reticulum transport vesicle membrane; Golgi-ER transport vesicle membrane
inter-Golgi transport vesicle membrane (GO:0012509)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a vesicle transporting substances within the Golgi.
Synonyms: inter-Golgi transport constitutive secretory pathway transport vesicle membrane
trans-Golgi network transport vesicle membrane (GO:0012510)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
Synonyms: TGN transport vesicle membrane; trans-Golgi network constitutive secretory pathway transport vesicle membrane
monolayer-surrounded lipid storage body (GO:0012511)
Namespace: cellular_component
Definition: A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
Synonyms: oil body; oilbody; oleosome; spherosome
morula development (GO:0014000)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum.
sclerenchyma cell differentiation (GO:0014001)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.
oligodendrocyte development (GO:0014003)
Namespace: biological_process
Definition: The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
Synonyms: oligodendrocyte cell development
microglia differentiation (GO:0014004)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
Synonyms: microglial cell differentiation
microglia development (GO:0014005)
Namespace: biological_process
Definition: The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
Synonyms: microglial cell development
regulation of microglia differentiation (GO:0014006)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
Synonyms: regulation of microglial cell differentiation
negative regulation of microglia differentiation (GO:0014007)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
Synonyms: down regulation of microglia differentiation; down-regulation of microglia differentiation; downregulation of microglia differentiation; inhibition of microglia differentiation; negative regulation of microglial cell differentiation
positive regulation of microglia differentiation (GO:0014008)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
Synonyms: activation of microglia differentiation; positive regulation of microglial cell differentiation; stimulation of microglia differentiation; up regulation of microglia differentiation; up-regulation of microglia differentiation; upregulation of microglia differentiation
glial cell proliferation (GO:0014009)
Namespace: biological_process
Definition: The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
Synonyms: glia proliferation
Schwann cell proliferation (GO:0014010)
Namespace: biological_process
Definition: The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
obsolete Schwann cell proliferation involved in axon regeneration (GO:0014011)
Namespace: biological_process
Definition: OBSOLETE. The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
peripheral nervous system axon regeneration (GO:0014012)
Namespace: biological_process
Definition: The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.
Synonyms: axon regeneration in peripheral nervous system
negative regulation of gliogenesis (GO:0014014)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.
Synonyms: down regulation of gliogenesis; down-regulation of gliogenesis; downregulation of gliogenesis; inhibition of gliogenesis
positive regulation of gliogenesis (GO:0014015)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.
Synonyms: activation of gliogenesis; stimulation of gliogenesis; up regulation of gliogenesis; up-regulation of gliogenesis; upregulation of gliogenesis
neuroblast differentiation (GO:0014016)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
neuroblast fate commitment (GO:0014017)
Namespace: biological_process
Definition: The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.
neuroblast fate specification (GO:0014018)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
neuroblast development (GO:0014019)
Namespace: biological_process
Definition: The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.
primary neural tube formation (GO:0014020)
Namespace: biological_process
Definition: The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
Synonyms: neural rod cavitation; primary neural tube morphogenesis; primary neurulation
secondary neural tube formation (GO:0014021)
Namespace: biological_process
Definition: The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.
Synonyms: medullary cord biosynthesis; medullary cord formation; medullary rod cavitation; neural rod formation; secondary neural tube rod cavitation; secondary neurulation
neural plate elongation (GO:0014022)
Namespace: biological_process
Definition: The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.