LiteFold/GO huggingface dataset:
obsolete N-acetylgalactosamine lectin (GO:0005533)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: N-acetylgalactosamine lectin
Comment: This term was made obsolete because it refers to a class of gene products.
galactose binding (GO:0005534)
Namespace: molecular_function
Definition: Binding to aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
Synonyms: galactose binding lectin
D-glucose binding (GO:0005536)
Namespace: molecular_function
Definition: Binding to D-enantiomers of glucose.
Synonyms: glucose binding
D-mannose binding (GO:0005537)
Namespace: molecular_function
Definition: Binding to mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
Synonyms: mannose binding; mannose binding lectin
glycosaminoglycan binding (GO:0005539)
Namespace: molecular_function
Definition: Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
hyaluronic acid binding (GO:0005540)
Namespace: molecular_function
Definition: Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
Synonyms: hyaluronan binding
obsolete acyl-CoA or acyl binding (GO:0005541)
Namespace: molecular_function
Definition: OBSOLETE. Interacting selectively with acyl-CoA or acyl, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group, or any group formally derived by removal of a hydroxyl group from the acid function of an organic acid.
Synonyms: acyl-CoA or acyl binding
Comment: This term was made obsolete because it was replaced by more appropriate terms.
folic acid binding (GO:0005542)
Namespace: molecular_function
Definition: Binding to folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
Synonyms: folate binding; vitamin B9 binding; vitamin M binding
phospholipid binding (GO:0005543)
Namespace: molecular_function
Definition: Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester.
calcium-dependent phospholipid binding (GO:0005544)
Namespace: molecular_function
Definition: Binding to a phospholipid, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
phosphatidylinositol-4,5-bisphosphate binding (GO:0005546)
Namespace: molecular_function
Definition: Binding to phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
Synonyms: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate binding; phosphatidylinositol 4,5-bisphosphate binding; PIP2 binding; PtdIns(4,5)P2 binding
phosphatidylinositol-3,4,5-trisphosphate binding (GO:0005547)
Namespace: molecular_function
Definition: Binding to phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
Synonyms: PIP3 binding
obsolete phospholipid transporter activity (GO:0005548)
Namespace: molecular_function
Definition: OBSOLETE. Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
Comment: This term was obsoleted because it refers to the substrate rather than to the transport mechanism as a primary classification.
pheromone binding (GO:0005550)
Namespace: molecular_function
Definition: Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
obsolete ubiquitin (GO:0005551)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Comment: This term was made obsolete because it represents a gene product.
obsolete ubiquitin-ribosomal protein fusion protein (GO:0005553)
Namespace: molecular_function
Definition: OBSOLETE. A protein encoded by some ubiquitin genes which consists of a single copy of ubiquitin fused to a ribosomal protein.
Synonyms: ubiquitin-ribosomal protein fusion protein
Comment: This term was made obsolete because it describes a gene product.
obsolete blood group antigen (GO:0005555)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: blood group antigen
Comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.
obsolete lymphocyte antigen (GO:0005557)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: lymphocyte antigen
Comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.
obsolete minor histocompatibility antigen (GO:0005558)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: minor histocompatibility antigen
Comment: This term was made obsolete because it represents a gene product, and because describing something as an 'antigen' means that an organism can produce antibodies to it, which says nothing about the gene product activity.
obsolete ribozyme (GO:0005559)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: ribozyme
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete nucleic acid (GO:0005561)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: nucleic acid
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete RNA (GO:0005562)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: RNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete transfer RNA (GO:0005563)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: transfer RNA
Comment: This term was made obsolete because it represents a gene product.
obsolete cytosolic tRNA (GO:0005564)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytosolic tRNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete mitochondrial tRNA (GO:0005565)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: mitochondrial tRNA
Comment: Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete ribosomal RNA (GO:0005566)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: ribosomal RNA
Comment: This term was made obsolete because it represents a gene product.
obsolete cytosolic ribosomal RNA (GO:0005567)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: cytosolic ribosomal RNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete mitochondrial rRNA (GO:0005568)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: mitochondrial rRNA
Comment: Note that this term was deleted from GO rather than being made obsolete and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete small nucleolar RNA (GO:0005569)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: small nucleolar RNA
Comment: This term was made obsolete because it represents gene products.
obsolete small nuclear RNA (GO:0005570)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: small nuclear RNA
Comment: This term was made obsolete because it represents gene products.
obsolete untranslated RNA (GO:0005571)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: untranslated RNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete RNA polymerase II transcribed untranslated RNA (GO:0005572)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: RNA polymerase II transcribed untranslated RNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
obsolete telomerase RNA (GO:0005573)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: telomerase RNA
Comment: This term was made obsolete because it represents a gene product.
obsolete DNA (GO:0005574)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: DNA
Comment: Note that this term was deleted from GO and was restored to the ontology in Feb 2003 to ensure that the ID is not reused.
cellular_component (GO:0005575)
Namespace: cellular_component
Definition: A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
Synonyms: cell or subcellular entity; cellular component; subcellular entity
Comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this.
extracellular region (GO:0005576)
Namespace: cellular_component
Definition: The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
Synonyms: extracellular
Comment: Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'.
fibrinogen complex (GO:0005577)
Namespace: cellular_component
Definition: A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
Synonyms: fibrinogen; fibrinogen alpha chain; fibrinogen beta chain; fibrinogen gamma chain
membrane attack complex (GO:0005579)
Namespace: cellular_component
Definition: A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
Synonyms: MAC; membrane attack complex protein alphaM chain; membrane attack complex protein beta2 chain; TCC; terminal complement complex
collagen trimer (GO:0005581)
Namespace: cellular_component
Definition: A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.
collagen type XV trimer (GO:0005582)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.
fibrillar collagen trimer (GO:0005583)
Namespace: cellular_component
Definition: Any triple helical collagen trimer that forms fibrils.
collagen type II trimer (GO:0005585)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.
collagen type III trimer (GO:0005586)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
collagen type IV trimer (GO:0005587)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.
collagen type V trimer (GO:0005588)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.
collagen type VI trimer (GO:0005589)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.
collagen type VII trimer (GO:0005590)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue. It binds laminin.
collagen type VIII trimer (GO:0005591)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.
collagen type XI trimer (GO:0005592)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type XI and type II alpha chains in alpha1(XI) alpha2(XI) alpha1(II) trimers; type XI collagen triple helices associate to form fibrils.
FACIT collagen trimer (GO:0005593)
Namespace: cellular_component
Definition: A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.
Comment: The acronym FACIT stands for fibril-associated collagen with interrupted triple helix.
collagen type IX trimer (GO:0005594)
Namespace: cellular_component
Definition: A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.
collagen type XII trimer (GO:0005595)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
collagen type XIV trimer (GO:0005596)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
collagen type XVI trimer (GO:0005597)
Namespace: cellular_component
Definition: A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.
obsolete short-chain collagen trimer (GO:0005598)
Namespace: cellular_component
Definition: OBSOLETE. Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.
Comment: This term was obsoleted because it was an unnecessary grouping term.
collagen type X trimer (GO:0005599)
Namespace: cellular_component
Definition: A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).
Comment: Collagen X trimers have been observed to form hexagonal lattices in vitro, but in vivo they have been found in a fibril associated form (PMID:19693541).
classical-complement-pathway C3/C5 convertase complex (GO:0005601)
Namespace: cellular_component
Definition: A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.
complement component C1 complex (GO:0005602)
Namespace: cellular_component
Definition: A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.
Synonyms: complement component C1q complex
obsolete complement component C2 complex (GO:0005603)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: complement component C2 complex
Comment: This term was made obsolete because prior to cleavage, complement component C2 is a single polypeptide rather than a complex, and after cleavage the products do not remain physically associated; there is thus no known biological entity corresponding to "complement C2 complex".
basement membrane (GO:0005604)
Namespace: cellular_component
Definition: A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
Synonyms: basal lamina; basement lamina; lamina densa
Comment: Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer.
laminin-111 trimer (GO:0005606)
Namespace: cellular_component
Definition: A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
Synonyms: laminin-1 complex; laminin-111 complex
laminin-211 trimer (GO:0005607)
Namespace: cellular_component
Definition: A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
Synonyms: laminin-2 complex; laminin-211 complex
laminin-121 trimer (GO:0005608)
Namespace: cellular_component
Definition: A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
Synonyms: laminin-121 complex; laminin-3 complex
laminin-221 trimer (GO:0005609)
Namespace: cellular_component
Definition: A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
Synonyms: laminin-221 complex; laminin-4 complex
laminin-311 trimer (GO:0005611)
Namespace: cellular_component
Definition: A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
Synonyms: laminin-311 complex; laminin-6 complex; laminin-6A complex
laminin-321 trimer (GO:0005612)
Namespace: cellular_component
Definition: A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
Synonyms: laminin-321 complex; laminin-7 complex; laminin-7A
obsolete laminin receptor protein (GO:0005613)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: laminin receptor protein
Comment: This term was made obsolete because it is out of date. It seems to be referring to the non-integrin 34/67kDa laminin receptor, which new research has shown to actually be a ribosomal protein of the SP2 family.
interstitial matrix (GO:0005614)
Namespace: cellular_component
Definition: A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
obsolete extracellular space (GO:0005615)
Namespace: cellular_component
Definition: OBSOLETE. That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
Synonyms: intercellular space
Comment: This term was obsoleted because it represents the same concept as extracellular region; GO:0005576.
larval serum protein complex (GO:0005616)
Namespace: cellular_component
Definition: A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.
cell wall (GO:0005618)
Namespace: cellular_component
Definition: The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
Comment: Not to be used for manual annotation. Please choose a more specific term: for bacteria, annotate to GO:0009274; peptidoglycan-based cell wall, for plants: annotate to GO:0009505 ; plant-type cell wall, for fungi: GO:0009277 ; fungal-type cell wall, and for archae, use GO:0030115 S-layer (see PMID:31214995).
ascospore wall (GO:0005619)
Namespace: cellular_component
Definition: The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
Synonyms: fungal-type spore wall
cellular bud scar (GO:0005621)
Namespace: cellular_component
Definition: Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
intracellular anatomical structure (GO:0005622)
Namespace: cellular_component
Definition: A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm.
Synonyms: internal to cell; intracellular; nucleocytoplasm; protoplasm; protoplast
obsolete cell (GO:0005623)
Namespace: cellular_component
Definition: OBSOLETE. The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
Comment: This term was obsoleted because it was redundant with the root class of the cell ontology, CL:0000000.
obsolete membrane fraction (GO:0005624)
Namespace: cellular_component
Definition: OBSOLETE. That fraction of cells, prepared by disruptive biochemical methods, that includes the plasma and other membranes.
Synonyms: membrane fraction
Comment: This term was made obsolete because it refers to a cell fractionation experimental result and not a bona fide cellular component.