LiteFold/GO huggingface dataset:
obsolete inorganic cation transmembrane transporter activity (GO:0022890)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
Synonyms: di-, tri-valent inorganic cation transmembrane transporter activity; divalent inorganic cation transmembrane transporter activity; monovalent inorganic cation transmembrane transporter activity; trivalent inorganic cation transmembrane transporter activity
Comment: The reason for obsoletion is that this term was an unnecessary and confusing grouping term.
low-affinity tryptophan transmembrane transporter activity (GO:0022893)
Namespace: molecular_function
Definition: Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
Synonyms: low-affinity tryptophan permease activity
intermediate conductance calcium-activated potassium channel activity (GO:0022894)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
Synonyms: IK calcium-activated potassium channel activity; IK KCa channels; intermediate conductance KCa channels
obsolete proton-dependent peptide secondary active transmembrane transporter activity (GO:0022897)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.
Synonyms: hydrogen/oligopeptide symporter
Comment: This term was obsoleted because it does not define a specific transport mechanism.
regulation of transmembrane transporter activity (GO:0022898)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
electron transport chain (GO:0022900)
Namespace: biological_process
Definition: A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.
respiratory electron transport chain (GO:0022904)
Namespace: biological_process
Definition: A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
Synonyms: 6-phosphofructokinase reduction; dihydrobiopterin reduction; dihydrolipoamide reduction; dihydrolipoylprotein reduction; dihydropteridine reduction; electron transfer; other pathways of electron transport; oxidized glutathione reduction; protein-disulfide reduction
nuclear migration to embryo sac poles (GO:0023002)
Namespace: biological_process
Definition: Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.
Synonyms: nuclear migration to female gametophyte poles; nuclear migration to megagametophyte poles; nucleus migration to embryo sac poles; nucleus migration to female gametophyte poles; nucleus migration to megagametophyte poles
nuclear migration to the embryo sac center (GO:0023003)
Namespace: biological_process
Definition: Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.
Synonyms: nuclear migration to the embryo sac centre; nuclear migration to the female gametophyte center; nuclear migration to the female gametophyte centre; nuclear migration to the megagametophyte center; nuclear migration to the megagametophyte centre; nucleus migration to the female gametophyte center; nucleus migration to the female gametophyte centre
obsolete activation of dopamine receptor signaling pathway (GO:0023004)
Namespace: biological_process
Definition: OBSOLETE. Any process that initiates the dopamine receptor protein signaling pathway through stimulation of the dopamine receptor.
Synonyms: activation of dopamine receptor signaling pathway; activation of dopamine receptor signalling pathway; initiation of dopamine receptor signaling pathway; stimulation of dopamine receptor signaling pathway
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by neurotransmitter (GO:0023005)
Namespace: biological_process
Definition: OBSOLETE. The process in which a neurotransmitter signal causes activation of a receptor.
Synonyms: signal initiation by neurotransmitter
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by amino acid (GO:0023006)
Namespace: biological_process
Definition: OBSOLETE. The process in which an amino acid signal causes activation of a receptor.
Synonyms: signal initiation by amino acid
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete ligand binding to T cell receptor (GO:0023007)
Namespace: biological_process
Definition: OBSOLETE. Binding of a diffusible ligand to a T cell receptor as part of a signaling process.
Synonyms: ligand binding to T cell receptor
Comment: This term was made obsolete because it is describing a binding molecular function.
obsolete initiation of T cell receptor signaling (GO:0023009)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal causes activation of T cell receptor signaling.
Synonyms: initiation of T cell receptor signaling; initiation of T cell receptor signalling
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete regulation of initiation of T cell receptor signaling (GO:0023010)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the initiation of T cell receptor signaling.
Synonyms: regulation of initiation of T cell receptor signaling; regulation of initiation of T cell receptor signalling
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor (GO:0023012)
Namespace: biological_process
Definition: OBSOLETE. The process in which binding of an MHC complex to T cell receptor causes activation of T cell receptor signaling.
Synonyms: initiation of T cell receptor signaling by binding of a MHC complex to T cell receptor; initiation of T cell receptor signalling by binding of a MHC complex to T cell receptor
Comment: This term was made obsolete because it is describing a binding molecular function.
obsolete signal transmission via diffusible molecule (GO:0023017)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via a diffusible molecule.
Synonyms: signal transmission via diffusible molecule; signaling via diffusible mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete T cell activation of signal transmission via diffusible molecule (GO:0023018)
Namespace: biological_process
Definition: OBSOLETE. The process in which signal transmission via a diffusible molecule is initiated by a T cell.
Synonyms: T cell activation of signal transmission via diffusible molecule
Comment: This term was made obsolete because the meaning of the term is ambiguous.
signal transduction involved in regulation of gene expression (GO:0023019)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
Synonyms: regulation of gene expression as a consequence of signal transmission
obsolete regulation of gene expression as a consequence of T cell signal transmission (GO:0023020)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a T cell signal is released and/or conveyed from one location to another.
Synonyms: regulation of gene expression as a consequence of T cell signal transmission
Comment: This term was made obsolete because the meaning of the term is ambiguous.
termination of T cell signal transduction (GO:0023022)
Namespace: biological_process
Definition: The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
MHC protein complex binding (GO:0023023)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex.
MHC class I protein complex binding (GO:0023024)
Namespace: molecular_function
Definition: Binding to a class I major histocompatibility complex.
MHC class Ib protein complex binding (GO:0023025)
Namespace: molecular_function
Definition: Binding to a class Ib major histocompatibility complex.
MHC class II protein complex binding (GO:0023026)
Namespace: molecular_function
Definition: Binding to a class II major histocompatibility complex.
MHC class I protein binding, via antigen binding groove (GO:0023027)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex class I molecules via the antigen binding groove.
MHC class I protein binding, via lateral surface (GO:0023028)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex class I molecules via the lateral surface.
MHC class Ib protein binding (GO:0023029)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex class Ib molecules.
MHC class Ib protein binding, via antigen binding groove (GO:0023030)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex class Ib molecules via the antigen binding groove.
MHC class Ib protein binding, via lateral surface (GO:0023031)
Namespace: molecular_function
Definition: Binding to a major histocompatibility complex class Ib molecules via the lateral surface.
CD40 signaling pathway (GO:0023035)
Namespace: biological_process
Definition: The series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms: CD40 signalling pathway
obsolete initiation of signal transduction (GO:0023036)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal causes activation of a receptor, for example, via a conformation change.
Synonyms: initiation of signal transduction; signal reception
Comment: This term was made obsolete because the meaning of the term is ambiguous. Note that this term was intended for the annotation of both ligands and receptors.
obsolete signal initiation by light (GO:0023037)
Namespace: biological_process
Definition: OBSOLETE. The process in which a light signal causes activation of a receptor.
Synonyms: signal initiation by light
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by diffusible mediator (GO:0023038)
Namespace: biological_process
Definition: OBSOLETE. The process in which a diffusible signal causes activation of a receptor.
Synonyms: signal initiation by diffusible mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by physical damage (GO:0023039)
Namespace: biological_process
Definition: OBSOLETE. The process in which a physical damage signal causes activation of a receptor.
Synonyms: signal initiation by physical damage
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signaling via ionic flux (GO:0023040)
Namespace: biological_process
Definition: OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via ionic flux.
Synonyms: signaling via ionic flux; signalling via ionic flux
Comment: This term was made obsolete because the meaning of the term is ambiguous.
neuronal signal transduction (GO:0023041)
Namespace: biological_process
Definition: The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.
obsolete signaling via protein/peptide mediator (GO:0023042)
Namespace: biological_process
Definition: OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a protein/peptide mediator.
Synonyms: signaling via protein/peptide mediator; signalling via protein/peptide mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signaling via lipid mediator (GO:0023043)
Namespace: biological_process
Definition: OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a lipid mediator.
Synonyms: signaling via lipid mediator; signalling via lipid mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signaling via chemical mediator (GO:0023044)
Namespace: biological_process
Definition: OBSOLETE. The process in which information is sent from one location to another, within a living organism or between living organisms, via a chemical mediator.
Synonyms: signaling via chemical mediator; signalling via chemical mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by chemical mediator (GO:0023047)
Namespace: biological_process
Definition: OBSOLETE. The process in which a chemical signal causes activation of a receptor.
Synonyms: signal initiation by chemical mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by lipid mediator (GO:0023048)
Namespace: biological_process
Definition: OBSOLETE. The process in which a lipid signal causes activation of a receptor.
Synonyms: signal initiation by lipid mediator
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete consequence of signal transmission (GO:0023050)
Namespace: biological_process
Definition: OBSOLETE. The steps whereby the downstream processes started by a signal are brought to a conclusion. Examples include destruction of cAMP by PDE, or endocytosis resulting from receptor phosphorylation. The termination process ends when the receptor has returned to its inactive state.
Synonyms: consequence of signal transmission; signal termination
Comment: This term was made obsolete because the term is no longer needed.
regulation of signaling (GO:0023051)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a signaling process.
Synonyms: regulation of signaling process; regulation of signalling process
signaling (GO:0023052)
Namespace: biological_process
Definition: The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
Synonyms: biological signaling; signaling process; signalling; signalling process; single organism signaling
Comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change.
obsolete signal initiation by mechanical effect (GO:0023053)
Namespace: biological_process
Definition: OBSOLETE. The process in which a mechanical signal causes activation of a receptor.
Synonyms: signal initiation by mechanical effect
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by stretch effect (GO:0023054)
Namespace: biological_process
Definition: OBSOLETE. The process in which a stretch signal causes activation of a receptor.
Synonyms: signal initiation by stretch effect
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal initiation by peptide hormone (GO:0023055)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is initiated by a peptide hormone.
Synonyms: signal initiation by peptide hormone
Comment: This term was made obsolete because the meaning of the term is ambiguous.
positive regulation of signaling (GO:0023056)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
Synonyms: positive regulation of signaling process; positive regulation of signalling process
negative regulation of signaling (GO:0023057)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
Synonyms: negative regulation of signaling process; negative regulation of signalling process
adaptation of signaling pathway (GO:0023058)
Namespace: biological_process
Definition: The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
Synonyms: adaptation of signalling pathway
positive adaptation of signaling pathway (GO:0023059)
Namespace: biological_process
Definition: The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
Synonyms: positive adaptation of signalling pathway
obsolete signal transmission (GO:0023060)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is released and/or conveyed from one location to another.
Synonyms: signal transmission
Comment: This term was made obsolete because it was an unnecessary grouping term.
signal release (GO:0023061)
Namespace: biological_process
Definition: The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
Synonyms: signal secretion
obsolete signal transmission via blood (GO:0023065)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via blood.
Synonyms: signal transmission via blood
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal transmission via vascular system (GO:0023066)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via the vascular system.
Synonyms: signal transmission via vascular system
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal transmission via phloem (GO:0023068)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via the phloem.
Synonyms: signal transmission via phloem
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal transmission via xylem (GO:0023069)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via the xylem.
Synonyms: signal transmission via xylem
Comment: This term was made obsolete because the meaning of the term is ambiguous.
obsolete signal transmission via air (GO:0023070)
Namespace: biological_process
Definition: OBSOLETE. The process in which a signal is conveyed via the air.
Synonyms: signal transmission via air
Comment: This term was made obsolete because the meaning of the term is ambiguous.
metal ion transport (GO:0030001)
Namespace: biological_process
Definition: The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: divalent metal ion export; divalent metal ion transport; heavy metal ion transport; metal ion export
intracellular monoatomic anion homeostasis (GO:0030002)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a steady state level of monoatomic anions within a cell. Monatomic anions (also called simple anions) are anions consisting of exactly one atom.
Synonyms: cellular anion homeostasis; cellular monoatomic anion homeostasis
intracellular monoatomic cation homeostasis (GO:0030003)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom.
Synonyms: cellular cation homeostasis; cellular monoatomic cation homeostasis
obsolete cellular monovalent inorganic cation homeostasis (GO:0030004)
Namespace: biological_process
Definition: OBSOLETE. Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete cellular di-, tri-valent inorganic cation homeostasis (GO:0030005)
Namespace: biological_process
Definition: OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent or trivalent cations at the level of a cell.
Synonyms: cellular di-, tri-valent inorganic cation homeostasis
obsolete heavy cellular metal ion homeostasis (GO:0030006)
Namespace: biological_process
Definition: OBSOLETE. Regulation of the levels, transport, and metabolism of ions of a heavy metal, a metal that can form a coordination bond with a protein, as opposed to an alkali or alkaline-earth metal that can only form an ionic bond; this definition includes the following biologically relevant heavy metals: Cd, Co, Cu, Fe, Hg, Mn, Mo, Ni, V, W, Zn.
Synonyms: heavy cellular metal ion homeostasis
Comment: This term was made obsolete because 'heavy metal' is an ambiguous grouping term which has no set meaning (see Pure Appl. Chem. Vol. 74, No. 5, pp. 793-807, 2002, for more information).
intracellular potassium ion homeostasis (GO:0030007)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a steady state level of potassium ions within a cell.
Synonyms: cellular potassium ion homeostasis
TRAPP complex (GO:0030008)
Namespace: cellular_component
Definition: A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.
Synonyms: transport protein particle; transport protein particle complex; TRAPP1; TRAPP2
obsolete complement factor H activity (GO:0030009)
Namespace: molecular_function
Definition: OBSOLETE. A cofactor for the serine protease complement factor I.
Synonyms: complement factor H activity
Comment: This term was made obsolete because it represents a gene product.
establishment of cell polarity (GO:0030010)
Namespace: biological_process
Definition: The specification and formation of anisotropic intracellular organization or cell growth patterns.
Synonyms: bud site selection/establishment of cell polarity; cell polarization
maintenance of cell polarity (GO:0030011)
Namespace: biological_process
Definition: The maintenance of established anisotropic intracellular organization or cell growth patterns.