LiteFold/GO huggingface dataset:
meiotic G2 phase (GO:0051331)
Namespace: biological_process
Definition: The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.
Synonyms: G2 phase of meiotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic S phase (GO:0051332)
Namespace: biological_process
Definition: The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.
Synonyms: premeiotic S-phase; S phase of meiotic cell cycle; S-phase of meiotic cell cycle
Comment: Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase (i.e mitotic DNA replication for mitotic S-phase). To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during).
meiotic nuclear membrane reassembly (GO:0051333)
Namespace: biological_process
Definition: The cell cycle process in which the reformation of the nuclear membranes during meiosis occurs.
Synonyms: meiotic nuclear envelope reassembly
meiosis I nuclear membrane reassembly (GO:0051334)
Namespace: biological_process
Definition: The reformation of the nuclear membranes during meiosis I.
Synonyms: meiosis I nuclear envelope reassembly
meiosis II nuclear membrane reassembly (GO:0051335)
Namespace: biological_process
Definition: The reformation of the nuclear membrane during meiosis II.
Synonyms: meiosis II nuclear envelope reassembly
regulation of hydrolase activity (GO:0051336)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
Synonyms: hydrolase regulator
amitosis (GO:0051337)
Namespace: biological_process
Definition: Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.
Synonyms: direct nuclear division; Remak nuclear division
obsolete regulation of lyase activity (GO:0051339)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
Synonyms: lyase regulator
Comment: This term was obsoleted because it represents a molecular function.
obsolete regulation of ligase activity (GO:0051340)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
Synonyms: ligase regulator
Comment: This term was obsoleted because it represents a molecular function.
regulation of oxidoreductase activity (GO:0051341)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Synonyms: oxidoreductase regulator
obsolete regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051342)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms: 3',5' cyclic nucleotide phosphodiesterase regulator; 3',5'-cyclic-AMP phosphodiesterase regulator; cAMP phosphodiesterase regulator; phosphodiesterase regulator; regulation of 3',5' cyclic nucleotide phosphodiesterase activity; regulation of 3',5'-cyclic-AMP phosphodiesterase activity; regulation of cAMP phosphodiesterase activity; regulation of cGMP phosphodiesterase activity; regulation of cyclic nucleotide phosphodiesterase activity
Comment: This term was obsoleted because it represents a molecular function.
negative regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051344)
Namespace: biological_process
Definition: Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms: 3',5' cyclic nucleotide phosphodiesterase inhibitor; 3',5'-cyclic-AMP phosphodiesterase inhibitor; cAMP phosphodiesterase inhibitor; down regulation of cyclic nucleotide phosphodiesterase activity; down-regulation of cyclic nucleotide phosphodiesterase activity; downregulation of cyclic nucleotide phosphodiesterase activity; inhibition of cyclic nucleotide phosphodiesterase activity; negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity; negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity; negative regulation of cAMP phosphodiesterase activity; negative regulation of cGMP phosphodiesterase activity; negative regulation of cyclic nucleotide phosphodiesterase activity; phosphodiesterase inhibitor
positive regulation of hydrolase activity (GO:0051345)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
Synonyms: activation of hydrolase activity; hydrolase activator; stimulation of hydrolase activity; up regulation of hydrolase activity; up-regulation of hydrolase activity; upregulation of hydrolase activity
obsolete positive regulation of transferase activity (GO:0051347)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
Synonyms: activation of transferase activity; stimulation of transferase activity; transferase activator; up regulation of transferase activity; up-regulation of transferase activity; upregulation of transferase activity
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
obsolete negative regulation of transferase activity (GO:0051348)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
Synonyms: down regulation of transferase activity; down-regulation of transferase activity; downregulation of transferase activity; inhibition of transferase activity; transferase inhibitor
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
positive regulation of lyase activity (GO:0051349)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms: activation of lyase activity; lyase activator; stimulation of lyase activity; up regulation of lyase activity; up-regulation of lyase activity; upregulation of lyase activity
obsolete negative regulation of lyase activity (GO:0051350)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
Synonyms: down regulation of lyase activity; down-regulation of lyase activity; downregulation of lyase activity; inhibition of lyase activity; lyase inhibitor
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
positive regulation of ligase activity (GO:0051351)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
Synonyms: activation of ligase activity; ligase activator; stimulation of ligase activity; up regulation of ligase activity; up-regulation of ligase activity; upregulation of ligase activity
obsolete negative regulation of ligase activity (GO:0051352)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
Synonyms: down regulation of ligase activity; down-regulation of ligase activity; downregulation of ligase activity; inhibition of ligase activity; ligase inhibitor
Comment: This term was obsoleted because it represents a molecular function.
positive regulation of oxidoreductase activity (GO:0051353)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
Synonyms: activation of oxidoreductase activity; oxidoreductase activator; ribonucleotide reductase activating enzyme activity; stimulation of oxidoreductase activity; up regulation of oxidoreductase activity; up-regulation of oxidoreductase activity; upregulation of oxidoreductase activity
negative regulation of oxidoreductase activity (GO:0051354)
Namespace: biological_process
Definition: Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
Synonyms: down regulation of oxidoreductase activity; down-regulation of oxidoreductase activity; downregulation of oxidoreductase activity; inhibition of oxidoreductase activity; oxidoreductase inhibitor
proprioception involved in equilibrioception (GO:0051355)
Namespace: biological_process
Definition: The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
Synonyms: equilibrioception by proprioception; perception of orientation with respect to gravity by proprioception; proprioception during equilibrioception
obsolete visual perception involved in equilibrioception (GO:0051356)
Namespace: biological_process
Definition: OBSOLETE. The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
Synonyms: equilibrioception by visual perception; perception of orientation with respect to gravity by visual perception; visual perception during equilibrioception
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one (GO:0051357)
Namespace: biological_process
Definition: OBSOLETE. The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
Synonyms: biosynthesis of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine; biosynthetic process of protein-protein cross-link via L-methionyl-L-tyrosyl-2-keto-5-iminopiperazine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine (GO:0051358)
Namespace: biological_process
Definition: OBSOLETE. The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus.
Synonyms: biosynthesis of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine; biosynthetic process of protein-protein cross-link via 2-imino-glutamic acid 5-imidazolinone glycine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine (GO:0051359)
Namespace: biological_process
Definition: OBSOLETE. The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor.
Synonyms: biosynthesis of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine; biosynthetic process of protein-protein cross-link via 2-imino-methionine 5-imidazolinone glycine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptide cross-linking via L-asparagine 5-imidazolinone glycine (GO:0051360)
Namespace: biological_process
Definition: OBSOLETE. The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
Synonyms: biosynthesis of protein-protein cross-link via L-asparagine 5-imidazolinone glycine; biosynthetic process of protein-protein cross-link via L-asparagine 5-imidazolinone glycine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein (GO:0051363)
Namespace: biological_process
Definition: OBSOLETE. The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
Comment: This term was obsoleted because it represents a molecular function.
obsolete N-terminal peptidyl-proline N-formylation (GO:0051364)
Namespace: biological_process
Definition: OBSOLETE. The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.
Comment: This term was obsoleted because it represents a molecular function.
cellular response to potassium ion starvation (GO:0051365)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.
Synonyms: cellular response to K+ ion deprivation; cellular response to K+ ion starvation; cellular response to potassium ion deprivation; cellular response to potassium starvation
protein decanoylation (GO:0051366)
Namespace: biological_process
Definition: The modification of a protein amino acid by formation of an ester or amide with decanoic acid.
Synonyms: protein amino acid decanoylation
obsolete peptidyl-threonine octanoylation (GO:0051368)
Namespace: biological_process
Definition: OBSOLETE. The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.
Comment: This term was obsoleted because it represents a molecular function.
obsolete peptidyl-threonine decanoylation (GO:0051369)
Namespace: biological_process
Definition: OBSOLETE. The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.
Comment: This term was obsoleted because it represents a molecular function.
obsolete ZASP binding (GO:0051370)
Namespace: molecular_function
Definition: OBSOLETE. Binding to Z-band alternatively spliced PDZ motif protein (ZASP). ZASP is a Z-band protein specifically expressed in heart and skeletal muscle. This protein contains N-terminal PDZ domain and C-terminal LIM domain.
Synonyms: Z-band alternatively spliced PDZ-motif protein binding; ZASP binding
Comment: This term was made obsolete because it represents binding to an individual protein.
muscle alpha-actinin binding (GO:0051371)
Namespace: molecular_function
Definition: Binding to muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
Synonyms: alpha-actinin 2 binding; alpha-actinin 3 binding
FATZ binding (GO:0051373)
Namespace: molecular_function
Definition: Binding to a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.
Synonyms: calsarcin 1 binding; calsarcin 2 binding; calsarcin 3 binding; calsarcin binding; FATZ 1 binding; FATZ 2 binding; FATZ 3 binding; filamin-, actinin- and telethonin-binding protein of the Z-disc of striated muscle
mannose-ethanolamine phosphotransferase activity (GO:0051377)
Namespace: molecular_function
Definition: Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.
Synonyms: addition of ethanolamine phosphate to mannose of GPI precursor; ethanolamine phosphate transferase activity; EtN-P transferase activity; phosphoethanolamine transferase activity
epinephrine binding (GO:0051379)
Namespace: molecular_function
Definition: Binding to epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
Synonyms: adrenaline binding
norepinephrine binding (GO:0051380)
Namespace: molecular_function
Definition: Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
Synonyms: noradrenaline binding
histamine binding (GO:0051381)
Namespace: molecular_function
Definition: Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
kinetochore organization (GO:0051383)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
Synonyms: kinetochore organisation; kinetochore organization and biogenesis
response to glucocorticoid (GO:0051384)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
Synonyms: response to glucocorticoid stimulus
response to mineralocorticoid (GO:0051385)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
Synonyms: response to mineralocorticoid stimulus
regulation of neurotrophin TRK receptor signaling pathway (GO:0051386)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
Synonyms: regulation of nerve growth factor receptor signaling pathway; regulation of nerve growth factor receptor signalling pathway; regulation of NGF receptor signaling pathway; regulation of NGF receptor signalling pathway
negative regulation of neurotrophin TRK receptor signaling pathway (GO:0051387)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
Synonyms: down regulation of nerve growth factor receptor signaling pathway; down-regulation of nerve growth factor receptor signaling pathway; downregulation of nerve growth factor receptor signaling pathway; inhibition of nerve growth factor receptor signaling pathway; negative regulation of nerve growth factor receptor signaling pathway; negative regulation of nerve growth factor receptor signalling pathway; negative regulation of NGF receptor signaling pathway; negative regulation of NGF receptor signalling pathway