LiteFold/GO huggingface dataset:
epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)
Namespace: biological_process
Definition: The movement of cilia of epithelial cells of the Left Right Organizer (LRO), also referred to as the node in mouse or the Kupffer's vesicle in zebrafish, resulting in the leftward fluid flow across the LRO and generation or transport of a signal which determines asymmetry in an organism's body plan with respect to the left and right halves.
Synonyms: cilium movement involved in determinationof L/R asymmetry; Kuppfer's vesicle cilium movement involved in determination of left/right asymmetry; nodal cilium movement involved in determination of left/right asymmetry
formation of a compartment boundary (GO:0060288)
Namespace: biological_process
Definition: Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
Synonyms: compartment boundary formation
compartment boundary maintenance (GO:0060289)
Namespace: biological_process
Definition: A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
transdifferentiation (GO:0060290)
Namespace: biological_process
Definition: The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.
long-term synaptic potentiation (GO:0060291)
Namespace: biological_process
Definition: A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
Synonyms: long-term potentiation; LTP
long-term synaptic depression (GO:0060292)
Namespace: biological_process
Definition: A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
Synonyms: long term depression; long term synaptic depression; LTD
germ plasm (GO:0060293)
Namespace: cellular_component
Definition: Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.
regulation of cilium movement involved in cell motility (GO:0060295)
Namespace: biological_process
Definition: Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.
regulation of cilium beat frequency involved in ciliary motility (GO:0060296)
Namespace: biological_process
Definition: Any process that modulates the frequency of cilium beating involved in ciliary motility.
regulation of sarcomere organization (GO:0060297)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms: regulation of sarcomere organisation
positive regulation of sarcomere organization (GO:0060298)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms: positive regulation of sarcomere organisation
negative regulation of sarcomere organization (GO:0060299)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
Synonyms: negative regulation of sarcomere organisation
regulation of cytokine activity (GO:0060300)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
obsolete positive regulation of cytokine activity (GO:0060301)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
Comment: This term was obsoleted because it represents a molecular function.
negative regulation of cytokine activity (GO:0060302)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
obsolete regulation of nucleosome density (GO:0060303)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the number of nucleosomes in a given region of a chromosome.
Comment: This term was obsoleted because it represents a readout and in some cases a phenotype, and the term can be misconstrued for chromatin compaction.
regulation of phosphatidylinositol dephosphorylation (GO:0060304)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
Synonyms: regulation of phosphoinositide dephosphorylation
regulation of membrane repolarization (GO:0060306)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.
regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
Synonyms: electrocardiogram T wave; regulation of ventricular cardiac muscle cell repolarization; regulation of ventricular cardiac muscle repolarization; regulation of ventricular cardiomyocyte membrane repolarization; ventricular repolarization
GTP cyclohydrolase I regulator activity (GO:0060308)
Namespace: molecular_function
Definition: Binds to and modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
elastin catabolic process (GO:0060309)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms: elastin breakdown; elastin catabolism; elastin degradation
regulation of elastin catabolic process (GO:0060310)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
Synonyms: regulation of elastin breakdown; regulation of elastin catabolism; regulation of elastin degradation
negative regulation of elastin catabolic process (GO:0060311)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
Synonyms: down-regulation of elastin catabolic process; negative regulation of elastin breakdown; negative regulation of elastin catabolism; negative regulation of elastin degradation
regulation of blood vessel remodeling (GO:0060312)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
Synonyms: regulation of blood vessel remodelling
negative regulation of blood vessel remodeling (GO:0060313)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
Synonyms: down-regulation of blood vessel remodeling; inhibition of blood vessel remodeling; negative regulation of blood vessel remodelling
regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)
Namespace: biological_process
Definition: Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)
Namespace: biological_process
Definition: Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
obsolete positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
Comment: This term was obsoleted because it represents a molecular function.
cardiac epithelial to mesenchymal transition (GO:0060317)
Namespace: biological_process
Definition: A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
Synonyms: heart epithelial to mesenchymal transition
definitive erythrocyte differentiation (GO:0060318)
Namespace: biological_process
Definition: Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.
Synonyms: definitive erythropoiesis; definitive RBC differentiation; definitive red blood cell differentiation
primitive erythrocyte differentiation (GO:0060319)
Namespace: biological_process
Definition: Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
Synonyms: primitive erythropoiesis; primitive RBC differentiation; primitive red blood cell differentiation
rejection of self pollen (GO:0060320)
Namespace: biological_process
Definition: The recognition and rejection of self pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.
Synonyms: self-incompatibility
acceptance of pollen (GO:0060321)
Namespace: biological_process
Definition: The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.
Synonyms: acceptance of non-self pollen; acceptance of self pollen; self-compatibility
head development (GO:0060322)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
head morphogenesis (GO:0060323)
Namespace: biological_process
Definition: The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
face development (GO:0060324)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.
face morphogenesis (GO:0060325)
Namespace: biological_process
Definition: The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
cell chemotaxis (GO:0060326)
Namespace: biological_process
Definition: The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
cytoplasmic actin-based contraction involved in cell motility (GO:0060327)
Namespace: biological_process
Definition: The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
cytoplasmic actin-based contraction involved in forward cell motility (GO:0060328)
Namespace: biological_process
Definition: The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.
Synonyms: cytoplasmic actin-based contraction involved in forward cell locomotion
obsolete cytoplasmic actin-based contraction involved in rearward cell motility (GO:0060329)
Namespace: biological_process
Definition: OBSOLETE. The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.
Synonyms: cytoplasmic actin-based contraction involved in rearward cell locomotion
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of response to type II interferon (GO:0060330)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
Synonyms: regulation of response to gamma-interferon; regulation of response to immune interferon; regulation of response to interferon-gamma; regulation of response to type II IFN
negative regulation of response to type II interferon (GO:0060331)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
Synonyms: negative regulation of response to gamma-interferon; negative regulation of response to immune interferon; negative regulation of response to interferon-gamma; negative regulation of response to type II IFN
positive regulation of response to type II interferon (GO:0060332)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
Synonyms: positive regulation of response to gamma-interferon; positive regulation of response to immune interferon; positive regulation of response to interferon-gamma; positive regulation of response to type II IFN
type II interferon-mediated signaling pathway (GO:0060333)
Namespace: biological_process
Definition: The series of molecular signals initiated by interferon-gamma binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
Synonyms: gamma-interferon-mediated signaling pathway; immune interferon signaling pathway; interferon-gamma-mediated signaling pathway; interferon-gamma-mediated signalling pathway; type II IFN-mediated signaling pathway
regulation of type II interferon-mediated signaling pathway (GO:0060334)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
Synonyms: regulation of gamma-interferon-mediated signaling pathway; regulation of immune interferon signaling pathway; regulation of interferon-gamma-mediated signaling pathway; regulation of interferon-gamma-mediated signalling pathway; regulation of type II IFN-mediated signaling pathway
positive regulation of type II interferon-mediated signaling pathway (GO:0060335)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of an interferon-gamma-mediated signaling pathway.
Synonyms: positive regulation of gamma-interferon-mediated signaling pathway; positive regulation of immune interferon-mediated signaling pathway; positive regulation of interferon-gamma-mediated signaling pathway; positive regulation of interferon-gamma-mediated signalling pathway; positive regulation of type II IFN-mediated pathway
type I interferon-mediated signaling pathway (GO:0060337)
Namespace: biological_process
Definition: The series of molecular signals initiated by type I interferon binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
Synonyms: type I interferon signaling pathway; type I interferon-activated signaling pathway
regulation of type I interferon-mediated signaling pathway (GO:0060338)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway.
Synonyms: regulation of type I interferon-mediated signalling pathway
positive regulation of type I interferon-mediated signaling pathway (GO:0060340)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway.
Synonyms: positive regulation of type I interferon-mediated signalling pathway
regulation of cellular localization (GO:0060341)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
Synonyms: regulation of cellular localisation
photoreceptor inner segment membrane (GO:0060342)
Namespace: cellular_component
Definition: The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
trabecula formation (GO:0060343)
Namespace: biological_process
Definition: The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
Synonyms: trabecula biogenesis; trabeculation
liver trabecula formation (GO:0060344)
Namespace: biological_process
Definition: The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.
Synonyms: liver trabecula biogenesis; liver trabeculation
bone trabecula formation (GO:0060346)
Namespace: biological_process
Definition: The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
Synonyms: bone trabecula biogenesis; bone trabeculation; skeletal trabecula biogenesis; skeletal trabecula formation; skeletal trabeculation
heart trabecula formation (GO:0060347)
Namespace: biological_process
Definition: The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.
Synonyms: cardiac trabecula formation; cardiac trabeculation; heart trabecula biogenesis; heart trabeculation
bone development (GO:0060348)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
bone morphogenesis (GO:0060349)
Namespace: biological_process
Definition: The process in which bones are generated and organized.
endochondral bone morphogenesis (GO:0060350)
Namespace: biological_process
Definition: The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.
cartilage development involved in endochondral bone morphogenesis (GO:0060351)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.
cell adhesion molecule production (GO:0060352)
Namespace: biological_process
Definition: The appearance of a cell adhesion molecule due to biosynthesis or secretion.
regulation of cell adhesion molecule production (GO:0060353)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
negative regulation of cell adhesion molecule production (GO:0060354)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
positive regulation of cell adhesion molecule production (GO:0060355)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
obsolete regulation of L-leucine import (GO:0060357)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.
Synonyms: regulation of L-leucine import; regulation of L-leucine uptake; regulation of leucine import; regulation of leucine uptake
Comment: This term was obsoleted because it is not specific enough relative to the localization of the substrate ; consider annotating to regulation of L-leucine import across plasma membrane ; GO:1905532.
obsolete negative regulation of L-leucine import (GO:0060358)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of L-leucine import. L-leucine import is the directed movement of leucine into a cell or organelle.
Synonyms: negative regulation of leucine import
Comment: This term was obsoleted because it is not specific enough relative to the localization of the substrate ; consider annotating to negative regulation of L-leucine import across plasma membrane ; GO:1905533.
response to ammonium ion (GO:0060359)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus.
Synonyms: response to ammonia