LiteFold/GO huggingface dataset:
T cell differentiation in thymus (GO:0033077)
Namespace: biological_process
Definition: The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
Synonyms: T cell development in thymus; thymic T cell differentiation; thymocyte cell differentiation; thymocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
extrathymic T cell differentiation (GO:0033078)
Namespace: biological_process
Definition: The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
Synonyms: extrathymic T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
immature T cell proliferation in thymus (GO:0033080)
Namespace: biological_process
Definition: The expansion of an immature T cell population by cell division in the thymus.
Synonyms: thymic T cell proliferation; thymocyte cell proliferation; thymocyte proliferation
regulation of T cell differentiation in thymus (GO:0033081)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
Synonyms: regulation of T cell development in thymus; regulation of thymic T cell differentiation; regulation of thymocyte cell differentiation; regulation of thymocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
regulation of extrathymic T cell differentiation (GO:0033082)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.
Synonyms: regulation of extrathymic T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
regulation of immature T cell proliferation (GO:0033083)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of immature T cell proliferation.
negative regulation of extrathymic T cell differentiation (GO:0033086)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.
Synonyms: negative regulation of extrathymic T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative regulation of immature T cell proliferation (GO:0033087)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.
negative regulation of immature T cell proliferation in thymus (GO:0033088)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.
Synonyms: negative regulation of thymic T cell proliferation; negative regulation of thymocyte cell proliferation; negative regulation of thymocyte proliferation
positive regulation of T cell differentiation in thymus (GO:0033089)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.
Synonyms: positive regulation of T cell development in thymus; positive regulation of thymic T cell differentiation; positive regulation of thymocyte cell differentiation; positive regulation of thymocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of extrathymic T cell differentiation (GO:0033090)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.
Synonyms: positive regulation of extrathymic T cell development
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of immature T cell proliferation (GO:0033091)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.
positive regulation of immature T cell proliferation in thymus (GO:0033092)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.
Synonyms: positive regulation of thymic T cell proliferation; positive regulation of thymocyte cell proliferation; positive regulation of thymocyte proliferation
Weibel-Palade body (GO:0033093)
Namespace: cellular_component
Definition: A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.
putrescine:2-oxoglutarate transaminase activity (GO:0033094)
Namespace: molecular_function
Definition: Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline.
Synonyms: butane-1,4-diamine:2-oxoglutarate aminotransferase activity; PAT activity; putrescine aminotransferase activity; putrescine transaminase activity; putrescine--2-oxoglutarate transaminase activity; putrescine-alpha-ketoglutarate transaminase activity; putrescine:2-oxoglutarate aminotransferase activity; putrescine:alpha-ketoglutarate aminotransferase activity; YgjG
aleurone grain (GO:0033095)
Namespace: cellular_component
Definition: A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.
Synonyms: aleurone body
amyloplast envelope (GO:0033096)
Namespace: cellular_component
Definition: The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
amyloplast membrane (GO:0033097)
Namespace: cellular_component
Definition: Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.
amyloplast inner membrane (GO:0033098)
Namespace: cellular_component
Definition: The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.
attachment organelle (GO:0033099)
Namespace: cellular_component
Definition: A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.
NuA3 histone acetyltransferase complex (GO:0033100)
Namespace: cellular_component
Definition: A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.
cellular bud membrane (GO:0033101)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding a cellular bud.
Synonyms: cellular bud plasma membrane
acidocalcisome membrane (GO:0033102)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an acidocalcisome.
chlorosome envelope (GO:0033105)
Namespace: cellular_component
Definition: The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.
Synonyms: chlorosome membrane
Comment: Note that the chlorosome envelope is not a single or double lipid bilayer, so this term is not a child of 'organelle membrane ; GO:0031090' or 'organelle envelope ; GO:0031967'.
Cvt vesicle (GO:0033107)
Namespace: cellular_component
Definition: A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).
Synonyms: cytoplasm to vacuole targeting vesicle; cytoplasm-to-vacuole targeting vesicle
mitochondrial respiratory chain complex assembly (GO:0033108)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex or between respiratory chain complexes to form high-order structures.
Cvt vesicle membrane (GO:0033110)
Namespace: cellular_component
Definition: Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.
Synonyms: cytoplasm to vacuole targeting vesicle membrane; cytoplasm-to-vacuole targeting vesicle membrane
attachment organelle membrane (GO:0033111)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.
cyanelle envelope (GO:0033112)
Namespace: cellular_component
Definition: The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
cyanelle membrane (GO:0033113)
Namespace: cellular_component
Definition: Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.
cyanelle thylakoid lumen (GO:0033114)
Namespace: cellular_component
Definition: The volume enclosed by a cyanelle thylakoid membrane.
endoplasmic reticulum-Golgi intermediate compartment membrane (GO:0033116)
Namespace: cellular_component
Definition: The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
Synonyms: ER-Golgi intermediate compartment membrane
esterosome (GO:0033117)
Namespace: cellular_component
Definition: A vesicle filled with crystalline protein that shows sequence similarities with various esterases.
esterosome membrane (GO:0033118)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.
positive regulation of RNA splicing (GO:0033120)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of RNA splicing.
regulation of purine nucleotide catabolic process (GO:0033121)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
Synonyms: regulation of purine nucleotide breakdown; regulation of purine nucleotide catabolism; regulation of purine nucleotide degradation
negative regulation of purine nucleotide catabolic process (GO:0033122)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
Synonyms: negative regulation of purine nucleotide breakdown; negative regulation of purine nucleotide catabolism; negative regulation of purine nucleotide degradation
positive regulation of purine nucleotide catabolic process (GO:0033123)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
Synonyms: positive regulation of purine nucleotide breakdown; positive regulation of purine nucleotide catabolism; positive regulation of purine nucleotide degradation
obsolete regulation of GTP catabolic process (GO:0033124)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.
Synonyms: regulation of GTP breakdown; regulation of GTP catabolism; regulation of GTP degradation
Comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.
obsolete negative regulation of GTP catabolic process (GO:0033125)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.
Synonyms: negative regulation of GTP breakdown; negative regulation of GTP catabolism; negative regulation of GTP degradation
Comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.
obsolete positive regulation of GTP catabolic process (GO:0033126)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of GTP, guanosine triphosphate.
Synonyms: positive regulation of GTP breakdown; positive regulation of GTP catabolism; positive regulation of GTP degradation
Comment: The reason for making this term obsolete is that it gets misused in cases where phosphates are simply being removed from a small molecule. We found no cases where these molecules genuinely underwent catabolism.
obsolete regulation of histone phosphorylation (GO:0033127)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of histone phosphorylation (GO:0033128)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of histone phosphorylation (GO:0033129)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
Comment: This term was obsoleted because it represents a molecular function.
acetylcholine receptor binding (GO:0033130)
Namespace: molecular_function
Definition: Binding to an acetylcholine receptor.
obsolete regulation of glucokinase activity (GO:0033131)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
Synonyms: glucokinase regulator
Comment: This term was obsoleted because it represents a molecular function.
negative regulation of glucokinase activity (GO:0033132)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
Synonyms: down regulation of glucokinase activity; down-regulation of glucokinase activity; downregulation of glucokinase activity; glucokinase inhibitor; inhibition of glucokinase activity
obsolete positive regulation of glucokinase activity (GO:0033133)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
Synonyms: glucokinase activator; stimulation of glucokinase activity; up regulation of glucokinase activity; up-regulation of glucokinase activity; upregulation of glucokinase activity
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
ubiquitin activating enzyme binding (GO:0033134)
Namespace: molecular_function
Definition: Binding to a ubiquitin activating enzyme, any of the E1 proteins.
regulation of peptidyl-serine phosphorylation (GO:0033135)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
negative regulation of peptidyl-serine phosphorylation (GO:0033137)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
positive regulation of peptidyl-serine phosphorylation (GO:0033138)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
Synonyms: regulation of serine phosphorylation of STAT3 protein
negative regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033140)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
Synonyms: down regulation of serine phosphorylation of STAT3 protein; down-regulation of serine phosphorylation of STAT3 protein; downregulation of serine phosphorylation of STAT3 protein; inhibition of serine phosphorylation of STAT3 protein; negative regulation of serine phosphorylation of STAT3 protein
positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
Synonyms: activation of serine phosphorylation of STAT3 protein; positive regulation of serine phosphorylation of STAT3 protein; up regulation of serine phosphorylation of STAT3 protein; up-regulation of serine phosphorylation of STAT3 protein; upregulation of serine phosphorylation of STAT3 protein
nuclear progesterone receptor binding (GO:0033142)
Namespace: molecular_function
Definition: Binding to a nuclear progesterone receptor.
Synonyms: progesterone receptor binding
regulation of intracellular steroid hormone receptor signaling pathway (GO:0033143)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
Synonyms: regulation of steroid hormone receptor signaling pathway; regulation of steroid hormone receptor signalling pathway
negative regulation of intracellular steroid hormone receptor signaling pathway (GO:0033144)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
Synonyms: negative regulation of steroid hormone receptor signaling pathway; negative regulation of steroid hormone receptor signalling pathway
positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
Synonyms: positive regulation of steroid hormone receptor signaling pathway; positive regulation of steroid hormone receptor signalling pathway
regulation of intracellular estrogen receptor signaling pathway (GO:0033146)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
Synonyms: regulation of estrogen receptor signaling pathway; regulation of estrogen receptor signalling pathway
negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
Synonyms: negative regulation of estrogen receptor signaling pathway; negative regulation of estrogen receptor signalling pathway
positive regulation of intracellular estrogen receptor signaling pathway (GO:0033148)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
Synonyms: positive regulation of estrogen receptor signaling pathway; positive regulation of estrogen receptor signalling pathway
FFAT motif binding (GO:0033149)
Namespace: molecular_function
Definition: Binding to a FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
cytoskeletal calyx (GO:0033150)
Namespace: cellular_component
Definition: A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.
V(D)J recombination (GO:0033151)
Namespace: biological_process
Definition: The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
Synonyms: V(D)J joining; V-D-J joining; V-D-J recombination; V-J joining; V-J recombination
immunoglobulin V(D)J recombination (GO:0033152)
Namespace: biological_process
Definition: The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
Synonyms: immunoglobulin V(D)J joining; immunoglobulin V-D-J joining; immunoglobulin V-D-J recombination; immunoglobulin V-J joining; immunoglobulin V-J recombination