LiteFold/GO huggingface dataset:
tail portion of tanycyte (GO:1990018)
Namespace: cellular_component
Definition: Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.
Synonyms: tail portion
protein storage vacuole organization (GO:1990019)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.
recurrent axon collateral (GO:1990020)
Namespace: cellular_component
Definition: Axon collateral that ramifies in the area of the soma of the cell of origin.
Synonyms: recurrent collateral
Schaffer axon collateral (GO:1990021)
Namespace: cellular_component
Definition: Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.
Synonyms: Schaffer collateral
obsolete RNA polymerase III complex import into nucleus (GO:1990022)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus.
Synonyms: DNA-directed RNA polymerase III complex import into nucleus; DNA-directed RNA polymerase III complex localization to nucleus; RNA polymerase III complex import into nucleus; RNA polymerase III complex localisation to nucleus; RNA polymerase III complex localization to nucleus
Comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.
mitotic spindle midzone (GO:1990023)
Namespace: cellular_component
Definition: The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
F bouton (GO:1990025)
Namespace: cellular_component
Definition: Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.
hippocampal mossy fiber expansion (GO:1990026)
Namespace: cellular_component
Definition: Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.
Synonyms: dentate gyrus granule cell axonal bouton; dentate gyrus mossy fiber expansion; mossy fiber expansion
intermediate voltage-gated calcium channel activity (GO:1990028)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.
Synonyms: R-type calcium channel
vasomotion (GO:1990029)
Namespace: biological_process
Definition: The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.
pericellular basket (GO:1990030)
Namespace: cellular_component
Definition: Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.
Synonyms: peri cellular basket; peri-cellular basket
pinceau fiber (GO:1990031)
Namespace: cellular_component
Definition: Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.
parallel fiber (GO:1990032)
Namespace: cellular_component
Definition: A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.
dendritic branch point (GO:1990033)
Namespace: cellular_component
Definition: The part of a dendritic tree where it branches, giving rise to a dendritic branch.
Synonyms: branch point of dendrite
calcium ion export across plasma membrane (GO:1990034)
Namespace: biological_process
Definition: The directed movement of calcium ions from inside of a cell, across the plasma membrane and into the extracellular region.
Synonyms: calcium ion efflux from cell; calcium ion export from cell
calcium ion import into sarcoplasmic reticulum (GO:1990036)
Namespace: biological_process
Definition: The directed movement of calcium ions into a sarcoplasmic reticulum.
Lewy body core (GO:1990037)
Namespace: cellular_component
Definition: The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.
Lewy body corona (GO:1990038)
Namespace: cellular_component
Definition: The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.
Synonyms: halo
hypolemmal cisterna (GO:1990039)
Namespace: cellular_component
Definition: Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.
Synonyms: hypolemmal cisternae
sub-surface cisterna (GO:1990040)
Namespace: cellular_component
Definition: Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.
Synonyms: sub-surface cisternae
obsolete glycerol dehydrogenase [NAD(P)+] activity (GO:1990042)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.
Synonyms: glycerol dehydrogenase activity, NAD or NADP as acceptor
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete 5' deoxyribonuclease (pyrimidine dimer) activity (GO:1990043)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.
Comment: The reason for obsoletion is that this term is not different from the parent term deoxyribonuclease (pyrimidine dimer) activity.
protein localization to lipid droplet (GO:1990044)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location on or within a lipid droplet.
Synonyms: protein localisation to adiposome; protein localisation to lipid body; protein localisation to lipid droplet; protein localisation to lipid particle; protein localization to adiposome; protein localization to lipid body; protein localization to lipid particle
stress-induced mitochondrial fusion (GO:1990046)
Namespace: biological_process
Definition: Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
Synonyms: mitochondrial fusion in response to stress; SIMH; stress-induced mitochondrial hyperfusion
spindle matrix (GO:1990047)
Namespace: cellular_component
Definition: A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.
anterograde neuronal dense core vesicle transport (GO:1990048)
Namespace: biological_process
Definition: The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.
Synonyms: anterograde dense core granule trafficking; anterograde dense core granule transport
retrograde neuronal dense core vesicle transport (GO:1990049)
Namespace: biological_process
Definition: The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.
Synonyms: retrograde dense core granule trafficking; retrograde dense core granule transport
phosphatidic acid transfer activity (GO:1990050)
Namespace: molecular_function
Definition: Removes a phosphatidic acid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.
Synonyms: intermembrane PA transfer activity; intermembrane phosphatidic acid transfer activity; phosphatidic acid carrier activity; phosphatidic acid transporter activity
activation of protein kinase C activity (GO:1990051)
Namespace: biological_process
Definition: Any process that initiates the activity of the inactive enzyme protein kinase C.
Synonyms: PKC activation; protein kinase C activation
ER to chloroplast lipid transport (GO:1990052)
Namespace: biological_process
Definition: The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.
Synonyms: endoplasmic reticulum to chloroplast lipid transport; ER to chloroplast lipid trafficking
response to temozolomide (GO:1990054)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
Comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. It was created to be used for cross-referencing by other ontologies. Direct annotations to this term may be amended during annotation QC.
phenylacetaldehyde synthase activity (GO:1990055)
Namespace: molecular_function
Definition: Catalyzes the reaction: L-phenylalanine + O2 + H2O + H+ = 2-phenylacetaldehyde + H2O2 + NH4+ + CO2.
Synonyms: aromatic aldehyde synthase
obsolete protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process (GO:1990056)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the phosphorylation of an amino acid residue in a substrate protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP, thereby targeting the substrate to the proteasomal ubiquitin mediated protein catabolic process.
Synonyms: protein kinase activity required for targeting substrate to proteasomal ubiquitin-dependent protein catabolic process
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
obsolete cell cycle arrest in response to DNA damage stimulus (GO:1990057)
Namespace: biological_process
Definition: OBSOLETE. The cell cycle regulatory process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of DNA damage from environmental insults or errors during metabolism.
Synonyms: cell cycle arrest in response to DNA damage stimulus
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
fruit replum development (GO:1990058)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.
fruit valve development (GO:1990059)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.
maltose transport complex (GO:1990060)
Namespace: cellular_component
Definition: Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.
Synonyms: maltose ABC transporter complex; maltose ATP-binding cassette transporter complex
bacterial degradosome (GO:1990061)
Namespace: cellular_component
Definition: The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.
Bam protein complex (GO:1990063)
Namespace: cellular_component
Definition: Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.
Synonyms: OMP complex
ground tissue pattern formation (GO:1990064)
Namespace: biological_process
Definition: The regionalization process that gives rise to the patterning of the ground tissue.
Synonyms: ground tissue patterning
Dxr protein complex (GO:1990065)
Namespace: cellular_component
Definition: A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Synonyms: 1-deoxy-D-xylulose 5-phosphate reductoisomerase complex
energy quenching (GO:1990066)
Namespace: biological_process
Definition: The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.
intrachromosomal DNA recombination (GO:1990067)
Namespace: biological_process
Definition: The process of DNA recombination occurring within a single chromosome.
Synonyms: intrastrand DNA recombination
seed dehydration (GO:1990068)
Namespace: biological_process
Definition: The seed development process whose outcome is the drying of a maturing seed.
stomatal opening (GO:1990069)
Namespace: biological_process
Definition: The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
TRAPPI protein complex (GO:1990070)
Namespace: cellular_component
Definition: A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.
Synonyms: TRAPP core complex
TRAPPII protein complex (GO:1990071)
Namespace: cellular_component
Definition: A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.
TRAPPIII protein complex (GO:1990072)
Namespace: cellular_component
Definition: A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.
perforation plate (GO:1990073)
Namespace: cellular_component
Definition: A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).
Comment: Part of a vessel member (PO:0002003). May be simple, with one perforation, or multiperforate, with more than one perforation. Perforation plates are usually on the end walls of a cell, but may also be on the side walls.
polyuridylation-dependent mRNA catabolic process (GO:1990074)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.
periciliary membrane compartment (GO:1990075)
Namespace: cellular_component
Definition: A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.
Synonyms: PCMC
obsolete cell wall polysaccharide catabolic process involved in abscission (GO:1990076)
Namespace: biological_process
Definition: OBSOLETE. Any cell wall polysaccharide catabolic process that is involved in abscission.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
primosome complex (GO:1990077)
Namespace: cellular_component
Definition: Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.
Synonyms: primosome
replication inhibiting complex (GO:1990078)
Namespace: cellular_component
Definition: A protein complex that inhibits multiple events of replication initiation during one replication cycle.
cartilage homeostasis (GO:1990079)
Namespace: biological_process
Definition: A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.
Synonyms: negative regulation of cartilage homeostasis; positive regulation of cartilage homeostasis; regulation of cartilage homeostasis
2-phenylethylamine receptor activity (GO:1990080)
Namespace: molecular_function
Definition: Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.
Synonyms: beta-phenylethylamine receptor activity
trimethylamine receptor activity (GO:1990081)
Namespace: molecular_function
Definition: Combining with the biogenic amine trimethylamine to initiate a change in cell activity.
DnaA-L2 complex (GO:1990082)
Namespace: cellular_component
Definition: A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.
DnaA-Hda complex (GO:1990083)
Namespace: cellular_component
Definition: A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.
DnaA-Dps complex (GO:1990084)
Namespace: cellular_component
Definition: A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.
Hda-beta clamp complex (GO:1990085)
Namespace: cellular_component
Definition: A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.
Synonyms: Hda-DnaN complex; Hda-dpo3b complex
lens fiber cell apoptotic process (GO:1990086)
Namespace: biological_process
Definition: Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity (GO:1990088)
Namespace: molecular_function
Definition: Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-coenzyme M + a [Co(I) methanol-specific corrinoid protein] + H+.
Synonyms: methanol-specific methylcobalamin: coenzyme M methyltransferase activity; methanol-specific methylcobalamin:coenzyme M methyltransferase activity; methanol-specific methylcobalamin:CoM methyltransferase activity; methylcobamide:coenzyme M methyltransferase activity; methylcobamide:CoM methyltransferase activity
Comment: This function is the second step in the pathway of methanogenesis from methanol.
response to nerve growth factor (GO:1990089)
Namespace: biological_process
Definition: A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
Synonyms: response to nerve growth factor stimulus
cellular response to nerve growth factor stimulus (GO:1990090)
Namespace: biological_process
Definition: A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
Synonyms: cellular response to NGF
sodium-dependent self proteolysis (GO:1990091)
Namespace: biological_process
Definition: The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
calcium-dependent self proteolysis (GO:1990092)
Namespace: biological_process
Definition: The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
obsolete negative regulation of N-methyl-D-aspartate receptor clustering (GO:1990093)
Namespace: biological_process
Definition: OBSOLETE. The negative regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
Synonyms: negative regulation of N-methyl-D-aspartate receptor clustering; negative regulation of NMDA receptor clustering
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
obsolete positive regulation of N-methyl-D-aspartate receptor clustering (GO:1990094)
Namespace: biological_process
Definition: OBSOLETE. The positive regulation of the receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
Synonyms: positive regulation of N-methyl-D-aspartate receptor clustering; positive regulation of NMDA receptor clustering
Comment: This term was obsoleted at the TermGenie Gatekeeper stage.
obsolete positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species (GO:1990095)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of transcription from RNA polymerase II promoter in response to superoxide (GO:1990096)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
Comment: This term was obsoleted because it represents a GO-CAM model.