LiteFold/GO huggingface dataset:
opsin binding (GO:0002046)
Namespace: molecular_function
Definition: Binding to an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
Synonyms: metarhodopsin binding
phenazine biosynthetic process (GO:0002047)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.
Synonyms: acridizine biosynthesis; acridizine biosynthetic process; azophenylene biosynthesis; azophenylene biosynthetic process; dibenzo-p-diazine biosynthesis; dibenzo-p-diazine biosynthetic process; dibenzopyrazine biosynthesis; dibenzopyrazine biosynthetic process
pyoverdine biosynthetic process (GO:0002049)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
positive regulation of neuroblast proliferation (GO:0002052)
Namespace: biological_process
Definition: Any process that activates or increases the rate of neuroblast proliferation.
Synonyms: activation of neuroblast proliferation; stimulation of neuroblast proliferation; up regulation of neuroblast proliferation; up-regulation of neuroblast proliferation; upregulation of neuroblast proliferation
positive regulation of mesenchymal cell proliferation (GO:0002053)
Namespace: biological_process
Definition: The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.
Synonyms: activation of mesenchymal cell proliferation; stimulation of mesenchymal cell proliferation; up regulation of mesenchymal cell proliferation; up-regulation of mesenchymal cell proliferation; upregulation of mesenchymal cell proliferation
nucleobase binding (GO:0002054)
Namespace: molecular_function
Definition: Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.
adenine binding (GO:0002055)
Namespace: molecular_function
Definition: Binding to adenine, a purine base.
Synonyms: 6-aminopurine binding
cytosine binding (GO:0002056)
Namespace: molecular_function
Definition: Binding to cytosine.
guanine binding (GO:0002057)
Namespace: molecular_function
Definition: Binding to guanine.
uracil binding (GO:0002058)
Namespace: molecular_function
Definition: Binding to uracil.
thymine binding (GO:0002059)
Namespace: molecular_function
Definition: Binding to thymine.
purine nucleobase binding (GO:0002060)
Namespace: molecular_function
Definition: Binding to a purine nucleobase, an organic nitrogenous base with a purine skeleton.
Synonyms: purine base binding; purine binding
pyrimidine nucleobase binding (GO:0002061)
Namespace: molecular_function
Definition: Binding to a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.
Synonyms: 1,3-diazine binding; pyrimidine base binding; pyrimidine binding
chondrocyte differentiation (GO:0002062)
Namespace: biological_process
Definition: The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
epithelial cell development (GO:0002064)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
columnar/cuboidal epithelial cell differentiation (GO:0002065)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
columnar/cuboidal epithelial cell development (GO:0002066)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
glandular epithelial cell differentiation (GO:0002067)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
glandular epithelial cell development (GO:0002068)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
columnar/cuboidal epithelial cell maturation (GO:0002069)
Namespace: biological_process
Definition: The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
epithelial cell maturation (GO:0002070)
Namespace: biological_process
Definition: The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
glandular epithelial cell maturation (GO:0002071)
Namespace: biological_process
Definition: The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
optic cup morphogenesis involved in camera-type eye development (GO:0002072)
Namespace: biological_process
Definition: The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.
Synonyms: optic cup morphogenesis involved in camera-style eye development
extraocular skeletal muscle development (GO:0002074)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
somitomeric trunk muscle development (GO:0002075)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
acrosome matrix dispersal (GO:0002077)
Namespace: biological_process
Definition: The proteolytic digestion of components in the acrosomal matrix that occurs as part of the acrosome reaction. The process can occur either in the cumulus oophorous facilitating the penetration of it by the sperm, or at the zona pellucida allowing the sperm to reach the plasma membrane of the egg where the inner acrosomal membrane of the sperm can interact with the egg plasma membrane.
membrane fusion involved in acrosome reaction (GO:0002078)
Namespace: biological_process
Definition: The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.
Synonyms: membrane fusion involved in the acrosomal reaction
inner acrosomal membrane (GO:0002079)
Namespace: cellular_component
Definition: The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
Comment: Note that this term is not a descendant of 'organelle inner membrane ; GO:0019866' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.
acrosomal membrane (GO:0002080)
Namespace: cellular_component
Definition: The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
outer acrosomal membrane (GO:0002081)
Namespace: cellular_component
Definition: The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.
Comment: Note that this term is not a descendant of 'organelle outer membrane ; GO:0031968' because the outer acrosomal membrane is a portion of the acrosomal membrane; the latter is a single lipid bilayer.
regulation of oxidative phosphorylation (GO:0002082)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
Synonyms: OXPHOS
obsolete 4-hydroxybenzoate decaprenyltransferase activity (GO:0002083)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.
Comment: This term was obsoleted because it represents a specific substrate of 4-hydroxybenzoate polyprenyltransferase activity ; GO:0008412.
protein depalmitoylation (GO:0002084)
Namespace: biological_process
Definition: The removal of palymitoyl groups from a lipoprotein.
inhibition of neuroepithelial cell differentiation (GO:0002085)
Namespace: biological_process
Definition: Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.
Synonyms: negative regulation of neural plate formation; repression of premature neural plate formation
diaphragm contraction (GO:0002086)
Namespace: biological_process
Definition: A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.
regulation of respiratory gaseous exchange by nervous system process (GO:0002087)
Namespace: biological_process
Definition: A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
Synonyms: neurological control of breathing; regulation of respiratory gaseous exchange by neurological system process
lens development in camera-type eye (GO:0002088)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms: lens development; lens development in camera-style eye
lens morphogenesis in camera-type eye (GO:0002089)
Namespace: biological_process
Definition: The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
Synonyms: lens morphogenesis; lens morphogenesis in camera-style eye
negative regulation of receptor internalization (GO:0002091)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
Synonyms: down regulation of receptor internalization; down-regulation of receptor internalization; downregulation of receptor internalization; inhibition of receptor internalization
auditory receptor cell morphogenesis (GO:0002093)
Namespace: biological_process
Definition: Any process that alters the size or shape of an auditory receptor cell.
Synonyms: hair cell morphogenesis
obsolete polyprenyltransferase activity (GO:0002094)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
caveolar macromolecular signaling complex (GO:0002095)
Namespace: cellular_component
Definition: A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).
Synonyms: caveolar macromolecular signalling complex
polkadots (GO:0002096)
Namespace: cellular_component
Definition: A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
Comment: Note that polkadots also contains some amount of MALT1. Interaction with MALT1 is required for formation of the polkadots.
tRNA wobble base modification (GO:0002097)
Namespace: biological_process
Definition: The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.
tRNA wobble uridine modification (GO:0002098)
Namespace: biological_process
Definition: The process in which a uridine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.
tRNA wobble guanine modification (GO:0002099)
Namespace: biological_process
Definition: The process in which a guanine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.
tRNA wobble adenosine to inosine editing (GO:0002100)
Namespace: biological_process
Definition: The process in which an adenosine at position 34 of a tRNA is post-transcriptionally converted to inosine. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.
tRNA wobble cytosine modification (GO:0002101)
Namespace: biological_process
Definition: The process in which a cytosine at position 34 of a tRNA is post-transcriptionally modified. The wobble nucleoside of the tRNA sequence  (position 34) corresponds to the first position of the anticodon.
podosome (GO:0002102)
Namespace: cellular_component
Definition: An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
Comment: Note that podosomes can be distinguished from other F-actin-rich structures or from other matrix contacts. For example, focal adhesions and focal contacts do not display a core structure of F-actin. Unlike focal adhesions, podosome assembly does not require de novo protein synthesis. However, most of the podosome ring components are found in focal adhesions and other cell-matrix contacts. Podosomes are typically found in cells that cross tissue boundaries, recruited to the leading edge of migrating cells, and are often sites of extracellular matrix degradation.
endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) (GO:0002103)
Namespace: biological_process
Definition: Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) (GO:0002104)
Namespace: biological_process
Definition: Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) (GO:0002105)
Namespace: biological_process
Definition: Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA) (GO:0002106)
Namespace: biological_process
Definition: Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
generation of mature 3'-end of 5S rRNA generated by RNA polymerase III (GO:0002107)
Namespace: biological_process
Definition: The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) (GO:0002108)
Namespace: biological_process
Definition: Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S) (GO:0002109)
Namespace: biological_process
Definition: Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
cotranscriptional mitochondrial rRNA nucleotide insertion (GO:0002110)
Namespace: biological_process
Definition: The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.
BRCA2-BRAF35 complex (GO:0002111)
Namespace: cellular_component
Definition: A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.
interleukin-33 receptor binding (GO:0002112)
Namespace: molecular_function
Definition: Binding to an interleukin-33 receptor.
Synonyms: IL-33; interleukin-33 receptor ligand
interleukin-33 binding (GO:0002113)
Namespace: molecular_function
Definition: Binding to interleukin-33.
Synonyms: IL-33 binding
interleukin-33 receptor activity (GO:0002114)
Namespace: molecular_function
Definition: Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: IL-33 receptor activity; IL-33R
store-operated calcium entry (GO:0002115)
Namespace: biological_process
Definition: A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.
Synonyms: calcium ion import; capacitative calcium entry; SOCE; store-operated calcium import
Comment: SOCE is initiated by response to stiumlation of membrane receptors leading to the hydrolysis ofphosphatidylinositol bisphosphate (PIP2), inositol 1,4,5-trisphosphate (IP3) generation, and IP3-mediated calcium ion release from the endoplasmic reticulum.
semaphorin receptor complex (GO:0002116)
Namespace: cellular_component
Definition: A stable binary complex of a semaphorin and a plexin, together forming a functional semaphorin receptor.
Synonyms: plexin-neurophilin complex
amphibian larval development (GO:0002117)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.