LiteFold/GO huggingface dataset:
articular cartilage development (GO:0061975)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of articular cartilage over time, from its formation to the mature structure.
Synonyms: articular cartilage of joint development
hip joint articular cartilage development (GO:0061977)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.
mandibular condyle articular cartilage development (GO:0061978)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of mandibular joint condyle articular cartilage over time, from its formation to the mature structure.
femoral head articular cartilage development (GO:0061979)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of femoral head articular cartilage over time, from its formation to the mature structure.
regulatory RNA binding (GO:0061980)
Namespace: molecular_function
Definition: Binding to a small regulatory RNA, a short RNA (usually 50-200 nt long) that is either independently transcribed or processed from a longer RNA by an RNAse enzyme.
obsolete 3-hydroxykynureninase activity (GO:0061981)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-3-hydroxykynurenine + H2O = 3-hydroxyanthranilate + L-alanine.
Comment: This term was obsoleted because it represents the same activity as kynureninase activity ; GO:0030429.
meiosis I cell cycle process (GO:0061982)
Namespace: biological_process
Definition: A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs.
Synonyms: first meiotic cell division
catabolite repression (GO:0061984)
Namespace: biological_process
Definition: A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.
carbon catabolite repression (GO:0061985)
Namespace: biological_process
Definition: A process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of the metabolism of other carbon sources.
negative regulation of transcription by glucose (GO:0061986)
Namespace: biological_process
Definition: Any process involving glucose that decreases the frequency, rate or extent or transcription.
negative regulation of transcription from RNA polymerase II promoter by glucose (GO:0061987)
Namespace: biological_process
Definition: Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.
karyosome formation (GO:0061988)
Namespace: biological_process
Definition: The chromosome organization process in which meiotic chromosomes in the germ cell nucleus cluster together to form a compact spherical structure called the karyosome.
sperm karyosome formation (GO:0061989)
Namespace: biological_process
Definition: The chromosome organization process in which meiotic chromosomes in the spem nucleus cluster together to form a compact spherical structure called the karyosome.
beta-ketodecanoyl-[acyl-carrier-protein] synthase activity (GO:0061990)
Namespace: molecular_function
Definition: Catalysis of the reaction: octanoyl-CoA + H+ + malonyl-[ACP] = 3-oxodecanoyl-[ACP] + CO2 + CoA.
obsolete ATP-dependent chaperone mediated protein folding (GO:0061992)
Namespace: biological_process
Definition: OBSOLETE. The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and dependent on ATP hydrolysis.
Comment: This term was obsoleted because it represents a molecular function.
calcium:proton antiporter complex (GO:0061993)
Namespace: cellular_component
Definition: A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
Synonyms: CAX1 homodimer; CAX1-CAX3 complex; CAX3 homodimer
ATP-dependent protein-DNA complex displacement activity (GO:0061995)
Namespace: molecular_function
Definition: An activity that displaces proteins or protein complexes from DNA, sometimes in a 'wire stripping' fashion, driven by ATP hydrolysis.
Synonyms: ATP-dependent protein-nucleic acid complex displacement activity
regulation of cardiac endothelial to mesenchymal transition (GO:0061999)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.
positive regulation of cardiac endothelial to mesenchymal transition (GO:0062000)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cardiac endothelial to mesenchymal trnasition.
negative regulation of cardiac endothelial to mesenchymal transition (GO:0062001)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac endothelial to mesenchymal transition.
obsolete regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity (GO:0062002)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.
Comment: This term was obsoleted because it represents a molecular function.
negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity (GO:0062003)
Namespace: biological_process
Definition: Any process that decreases the frequency or rate of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity.
secondary palate development (GO:0062009)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences.
primitive palate development (GO:0062010)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure.
mitochondrial respiratory chain complex IV pre-assembly complex (GO:0062011)
Namespace: cellular_component
Definition: A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.
Synonyms: COX pre-assemply complex; COX1 preassemply complex
regulation of small molecule metabolic process (GO:0062012)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of a small molecule metabolic process.
Synonyms: regulation of small molecule metabolism
positive regulation of small molecule metabolic process (GO:0062013)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.
Synonyms: positive regulation of small molecule metabolism
negative regulation of small molecule metabolic process (GO:0062014)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
Synonyms: negative regulation of small molecule metabolism
obsolete mitotic cohesin dsDNA (leading strand) loading (GO:0062021)
Namespace: biological_process
Definition: OBSOLETE. The protein localization to chromatin by which a cohesin ring complex is topologically linked to dsDNA (leading strand) as part of the mitotic cell cycle.
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete mitotic cohesin ssDNA (lagging strand) loading (GO:0062022)
Namespace: biological_process
Definition: OBSOLETE. The ATP-dependent protein localization to chromatin by which a cohesin ring complex is topologically linked to ssDNA (lagging strand) which is already linked to a dsDNA (leading strand) molecule as part of the mitotic cell cycle.
Synonyms: second-DNA capture
Comment: The reason for obsoletion is that this term represents a molecular function.
obsolete collagen-containing extracellular matrix (GO:0062023)
Namespace: cellular_component
Definition: OBSOLETE. An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
Synonyms: collagen-containing ECM
Comment: This term was obsoleted because it was not clearly defined and usage has been inconsistent.
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process (GO:0062026)
Namespace: biological_process
Definition: Any process that stops or decreases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
positive regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process (GO:0062027)
Namespace: biological_process
Definition: Any process that starts or increases the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
regulation of stress granule assembly (GO:0062028)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
negative regulation of stress granule assembly (GO:0062030)
Namespace: biological_process
Definition: Any process that stops or decreases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
filamentous growth MAPK cascade (GO:0062031)
Namespace: biological_process
Definition: A MAPK cascade containing at least the Kss1 MAP kinase. It starts with the activation of Ste20, a MAP4K, which activates Ste11, a MAP3K, which in turn activate Ste7, a MAP2K, which activates Kss1. The kinases in each tier phosphorylate and activate the kinases in the downstream tier. The filamentous growth MAPK cascade is activated as a result of partial nutrient deprivation and  results in filamentous growth.
cichorine biosynthetic process (GO:0062032)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cichorine, a secondary metabolite found in some species of fungi.
Synonyms: cichorine anabolism; cichorine biosynthesis; cichorine formation; cichorine synthesis
positive regulation of mitotic sister chromatid segregation (GO:0062033)
Namespace: biological_process
Definition: Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis.
L-pipecolic acid biosynthetic process (GO:0062034)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-pipecolic acid, a metabolite of lysine.
Synonyms: L-pipecolate biosynthetic process
sensory perception of cold stimulus (GO:0062035)
Namespace: biological_process
Definition: The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
sensory perception of hot stimulus (GO:0062036)
Namespace: biological_process
Definition: The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.
D-loop DNA binding (GO:0062037)
Namespace: molecular_function
Definition: Binding to a DNA D-loop. A D-loop is a three-stranded DNA structure formed by the invasion of a single DNA strand that base pairs with one strand of duplex DNA, while the rest of the double-stranded DNA does not unwind.
Synonyms: DNA displacement loop binding
positive regulation of pheromone response MAPK cascade (GO:0062038)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a pheromone response MAPK cascade.
fungal biofilm matrix (GO:0062040)
Namespace: cellular_component
Definition: An extracellular matrix lying external to fungal cells. The fungal biofilm matrix consists of polysaccharides, proteins, lipids, and nucleic acids. Fungal biofilms mediate adherence to host tissues, and provide protection from host immune defenses.
regulation of cardiac epithelial to mesenchymal transition (GO:0062042)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
positive regulation of cardiac epithelial to mesenchymal transition (GO:0062043)
Namespace: biological_process
Definition: Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
negative regulation of cardiac epithelial to mesenchymal transition (GO:0062044)
Namespace: biological_process
Definition: Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
L-lysine:pyruvate alpha-transaminase activity (GO:0062045)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-lysine + pyruvate= epsilon-amino-alpha-ketocaproic acid (KAC) + alanine.
Synonyms: L-lysine alpha-aminotransferase activity
dehydropipecolic acid reductase activity (GO:0062046)
Namespace: molecular_function
Definition: Catalysis of the reaction: dehydropipecolic acid + NAD(P)H + H+ = L-pipecolic acid + NAD(P)+.
pipecolic acid N-hydroxylase activity (GO:0062047)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-pipecolic acid + NAD(P)H + O2 + H+ = N-hydroxypipecolic acid + NAD(P)+ + H2O.
lymphotoxin complex (GO:0062048)
Namespace: cellular_component
Definition: A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations.
Synonyms: lymphotoxin alpha-beta
protein phosphatase inhibitor complex (GO:0062049)
Namespace: cellular_component
Definition: A protein-containing complex that inhibits protein phosphatase activity by directly binding to a protein phosphatase.
GPI-mannose ethanolamine phosphate phosphodiesterase activity (GO:0062050)
Namespace: molecular_function
Definition: A phosphoric diester hydrolase activity that removes the ethanolamine phosphate from mannose 2 of a GPI anchor.
lipopolysaccharide transport system (GO:0062051)
Namespace: cellular_component
Definition: A protein-containing complex that functions to transport lipopolysaccharide from its site of synthesis at the cytoplasmic membrane across the periplasm to the outer membrane in an ATP-dependent manner.
starch granule initiation (GO:0062052)
Namespace: biological_process
Definition: The sequence of events that initiates (or primes) the synthesis of semi-crystalline starch granules within photosynthetic chloroplasts or non-photosynthetic amyloplasts.
photosynthetic state transition (GO:0062055)
Namespace: biological_process
Definition: A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.
compound eye pigment cell differentiation (GO:0062056)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.
L-aspartate:fumarate antiporter activity (GO:0062057)
Namespace: molecular_function
Definition: Enables the transport of L-aspartate and fumarate across a membrane according to the reaction L-aspartate (out) + fumarate (in) = L-aspartate (in) + fumarate (out).
transcription factor TFIIH holo complex binding (GO:0062058)
Namespace: molecular_function
Definition: Binding to a transcription factor TFIIH holo complex.
FACT complex binding (GO:0062059)
Namespace: molecular_function
Definition: Binding to a FACT complex.
NuA4 histone acetyltransferase complex binding (GO:0062060)
Namespace: molecular_function
Definition: Binding to a NuA4 histone acetyltransferase complex.
TAP complex binding (GO:0062061)
Namespace: molecular_function
Definition: Binding to a TAP complex.
oligosaccharyltransferase complex binding (GO:0062062)
Namespace: molecular_function
Definition: Binding to an oligosaccharyltransferase complex.
BBSome binding (GO:0062063)
Namespace: molecular_function
Definition: Binding to a BBSome complex.
box C/D methylation guide snoRNP complex binding (GO:0062064)
Namespace: molecular_function
Definition: Binding to a box C/D methylation guide snoRNP complex.
box H/ACA snoRNP complex binding (GO:0062065)
Namespace: molecular_function
Definition: Binding to a box H/ACA snoRNP complex.
chloroplast photosystem I binding (GO:0062067)
Namespace: molecular_function
Definition: Binding to a chloroplast photosystem I.
chloroplast photosystem II binding (GO:0062068)
Namespace: molecular_function
Definition: Binding to a chloroplast photosystem II.
GARP complex binding (GO:0062069)
Namespace: molecular_function
Definition: Binding to a GARP complex.
SAGA complex binding (GO:0062070)
Namespace: molecular_function
Definition: Binding to a SAGA complex.
histone H3K9me2/3 reader activity (GO:0062072)
Namespace: molecular_function
Definition: A histone reader that recognizes a histone H3 trimethylated at lysine 9. In some organisms, there is only H3K9me2, not H3K9me3, but this modification is recognized by homologous readers.
Synonyms: H3K9me3 modified histone binding; histone H3K9me2 reader activity; histone H3K9me3 reader activity
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
pollen aperture (GO:0062074)
Namespace: cellular_component
Definition: An area where exine is reduced or absent, in the pollen wall.
pollen aperture formation (GO:0062075)
Namespace: biological_process
Definition: The cellular component assembly process of forming pollen apertures, areas where exine is reduced or absent, in the pollen cell wall.
acyl-CoA (8-3)-desaturase activity (GO:0062076)
Namespace: molecular_function
Definition: Catalysis of the reaction: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA) and add a fourth double bond (a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA).
Synonyms: acyl-CoA D5-desaturase activity; acyl-CoA delta(5)-desaturase activity; acyl-CoA delta5-desaturase activity
phenylacetyl-CoA 1,2-epoxidase complex (GO:0062077)
Namespace: cellular_component
Definition: A protein complex capable of catalysing the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.
Synonyms: paaABCE complex
TSC1-TSC2 complex binding (GO:0062078)
Namespace: molecular_function
Definition: Binding to a TSC1-TSC2 complex.
Synonyms: tuberin sclerosis complex binding; tuberin-hamartin complex binding
ATG2-ATG18 complex (GO:0062079)
Namespace: cellular_component
Definition: A protein complex essential for autophagy during nutrient deprivation, a catabolic process that sequesters undesired cellular material into autophagosomes for delivery to lysosomes for degradation. Contributes to nutrition homeostasis and damage control in eukaryotic cells. Functions at a late step of autophagosome formation for efficient completion of sequestration, probably through facilitating recruitment of ATG8-phosphatidylethanolamine (PE) to the preautophagosomal structure (PAS) and/or its protection from deconjugation by ATG4. Composed of ATG2 and ATG18 in Saccharomyces cerevisiae.
activating MHC class Ib receptor activity (GO:0062081)
Namespace: molecular_function
Definition: Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.
HLA-E specific inhibitory MHC class Ib receptor activity (GO:0062082)
Namespace: molecular_function
Definition: Combining with a MHC class Ib molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
HLA-G specific inhibitory MHC class Ib receptor activity (GO:0062083)
Namespace: molecular_function
Definition: Combining with a MHC class Ib molecule of the HLA-G subclass to mediate signaling that inhibits activation of a lymphocyte.
regulation of capsule polysaccharide biosynthetic process (GO:0062084)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
positive regulation of capsule polysaccharide biosynthetic process (GO:0062085)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
regulation of vein smooth muscle contraction (GO:0062086)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of vein smooth muscle contraction.
positive regulation of vein smooth muscle contraction (GO:0062087)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of vein smooth muscle contraction.
negative regulation of vein smooth muscle contraction (GO:0062088)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of vein smooth muscle contraction.
regulation of taurine biosynthetic process (GO:0062089)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of taurine biosynthesis.