LiteFold/GO huggingface dataset:
symbiont genome entry into host cell via pore formation in plasma membrane (GO:0044694)
Namespace: biological_process
Definition: Entry of a symbiont's genome into a host cell by a pore formed by the symbiont in the host cell. Examples of this process include injection by a non-enveloped virus of the viral genome into the host cytoplasm, usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.
Synonyms: membrane puncture-mediated penetration of viral genome into host cell; pore-mediated entry of viral genome into host cell; pore-mediated penetration of viral genome into host cell; viral entry via genome injection; viral genome delivery via icosahedral vertex; viral genome translocation; viral pore-forming protein
Comment: This mechanism is used by animal viruses such as poliovirus. Various tailed bacteriophages also carry specialized proteins which open a pore or a channel in the host membrane(s) to allow genome delivery into host cytoplasm.
Dsc E3 ubiquitin ligase complex (GO:0044695)
Namespace: cellular_component
Definition: An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.
killing by virus of host cell by post-segregational killing (GO:0044696)
Namespace: biological_process
Definition: The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.
Synonyms: killing by virus of host cell by PSK; killing by virus of host cell by toxin-antitoxin system
Comment: Note that this process occurs after the cell division partitioning event.
HICS complex (GO:0044697)
Namespace: cellular_component
Definition: A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.
obsolete morphogenesis of symbiont in host cell (GO:0044698)
Namespace: biological_process
Definition: OBSOLETE. The process in which a symbiont undergoes a change in shape or form, within the host's cell.
Comment: This term was obsoleted because it represents both a process and a location.
multi-organism reproductive process (GO:0044703)
Namespace: biological_process
Definition: A biological process that directly contributes to the process of producing new individuals, involving another organism.
multi-multicellular organism process (GO:0044706)
Namespace: biological_process
Definition: A multicellular organism process which involves another multicellular organism of the same or different species.
8-oxo-dGDP phosphatase activity (GO:0044715)
Namespace: molecular_function
Definition: Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
8-oxo-GDP phosphatase activity (GO:0044716)
Namespace: molecular_function
Definition: Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.
siderophore transmembrane transport (GO:0044718)
Namespace: biological_process
Definition: The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.
Synonyms: siderophore membrane transport
Comment: Note that this term is not intended for use in annotating lateral movement within membranes.
regulation of imaginal disc-derived wing size (GO:0044719)
Namespace: biological_process
Definition: Any process that modulates the size of an imaginal disc-derived wing.
negative regulation of imaginal disc-derived wing size (GO:0044720)
Namespace: biological_process
Definition: Any process that reduces the size of an imaginal disc-derived wing.
protein import into peroxisome matrix, substrate release (GO:0044721)
Namespace: biological_process
Definition: The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.
renal phosphate excretion (GO:0044722)
Namespace: biological_process
Definition: The elimination of phosphate ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
Synonyms: renal phosphate ion excretion
epigenetic programming in the zygotic pronuclei (GO:0044725)
Namespace: biological_process
Definition: The global programming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.
Synonyms: chromatin reprogramming in the zygote
epigenetic programing of female pronucleus (GO:0044726)
Namespace: biological_process
Definition: The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.
Synonyms: maintenance of DNA methylation at imprinted genes; protection of DNA demethylation of female pronucleus; protection of DNA methylation in female pronucleus
epigenetic programing of male pronucleus (GO:0044727)
Namespace: biological_process
Definition: The global programming of epigenetic modifications in the male pronucleus of the newly fertilized zygote. The most major change in the paternal genome is DNA demethylation, which takes place before the first cell division.
Synonyms: DNA demethylation of male pronucleus; epigenetic reprograming of male pronucleus; epigenetic reprograming of paternal genome in zygote
obsolete DNA methylation or demethylation (GO:0044728)
Namespace: biological_process
Definition: OBSOLETE. The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.
Synonyms: changes in DNA methylation
Comment: This term was obsoleted because it is an unnecessary grouping class.
bone sialoprotein binding (GO:0044730)
Namespace: molecular_function
Definition: Binding to a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.
Synonyms: bone sialoprotein II binding
Ost-alpha/Ost-beta complex (GO:0044731)
Namespace: cellular_component
Definition: A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.
Synonyms: (Ost)2 complex; Ost alpha-Ost beta complex; SLC51 complex
mitotic spindle pole body (GO:0044732)
Namespace: cellular_component
Definition: The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
venom-mediated perturbation of pH-gated ion channel activity (GO:0044733)
Namespace: biological_process
Definition: A process in which an organism alters or subverts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.
Synonyms: envenomation resulting in modulation of acid-sensing ion channel activity in another organism; envenomation resulting in modulation of acid-sensing ion channel activity in other organism; envenomation resulting in modulation of ASIC channel activity in other organism; venom-mediated perturbation of acid-sensing ion channel activity
venom-mediated activation of pH-gated ion channel activity (GO:0044734)
Namespace: biological_process
Definition: A process in which an organism initiates, promotes, or enhances the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.
Synonyms: envenomation resulting in positive regulation of acid-sensing ion channel activity in another organism; envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism; envenomation resulting in positive regulation of ASIC channel activity in other organism; venom-mediated activation of acid-sensing ion channel activity
venom-mediated inhibition of pH-gated ion channel activity (GO:0044735)
Namespace: biological_process
Definition: A process in which an organism inhibits or disrupts the activity of a pH-gated (also known as acid-sensing ion channel (ASIC)) in another organism via the action of a venom.
Synonyms: envenomation resulting in negative regulation of acid-sensing ion channel activity in another organism; envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism; envenomation resulting in negative regulation of ASIC channel activity in other organism; venom-mediated inhibition of acid-sensing ion channel activity
obsolete acid-sensing ion channel activity (GO:0044736)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
Synonyms: ASIC activity
Comment: The reason for obsoletion is that this activity represents a gene family with GO:0160128 pH-gated channel activity.
obsolete modulation of acid-sensing ion channel in another organism (GO:0044737)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism.
Synonyms: modulation of acid-sensing ion channel in other organism; regulation of acid-sensing ion channel in other organism; regulation of ASIC channel in other organism
Comment: This term was obsoleted because it is too general.
obsolete negative regulation of acid-sensing ion channel in another organism (GO:0044738)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.
Synonyms: negative regulation of acid-sensing ion channel in other organism; negative regulation of ASIC channel in other organism
Comment: This term was obsoleted because it is too general.
obsolete positive regulation of acid-sensing ion channel in another organism (GO:0044739)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism.
Synonyms: positive regulation of acid-sensing ion channel in other organism; positive regulation of ASIC channel in other organism
Comment: This term was obsoleted because it is too general.
obsolete negative regulation of sensory perception of pain in another organism (GO:0044740)
Namespace: biological_process
Definition: OBSOLETE. A process that negatively regulates the sensory perception of pain in a different organism.
Synonyms: inhibition of sensory perception of pain in another organism; negative regulation of sensory perception of pain in other organism
Comment: This term was obsoleted because it is too general.
venom-mediated suppression of sensory perception of pain (GO:0044741)
Namespace: biological_process
Definition: A process in which an organism inhibits or disrupts sensory perception of pain in another organism via the action of a venom.
Synonyms: envenomation resulting in inhibition of sensory perception of pain in other organism; envenomation resulting in negative regulation of sensory perception of pain in another organism; envenomation resulting in negative regulation of sensory perception of pain in other organism
protein transmembrane import into intracellular organelle (GO:0044743)
Namespace: biological_process
Definition: The directed movement of proteins into an intracellular organelle, across a membrane.
pre-miRNA 3'-end processing (GO:0044747)
Namespace: biological_process
Definition: Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.
Synonyms: mature miRNA 3'-end processing; miRNA 3' end terminal trimming; miRNA 3'-end processing; miRNA trimming
3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing (GO:0044748)
Namespace: molecular_function
Definition: Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.
Synonyms: exonucleolytic trimming to generate 3' end of miRNA
high-affinity nickel cation transmembrane transporter activity (GO:0044750)
Namespace: molecular_function
Definition: Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
cellular response to human chorionic gonadotropin stimulus (GO:0044751)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
Synonyms: cellular response to human chorionic gonadotrophin stimulus
response to human chorionic gonadotropin (GO:0044752)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
Synonyms: response to human chorionic gonadotropin stimulus
amphisome (GO:0044753)
Namespace: cellular_component
Definition: Intermediate organelles formed during macroautophagy through the fusion between autophagosomes and endosomes.
autolysosome (GO:0044754)
Namespace: cellular_component
Definition: A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
Synonyms: AVd; degrading autophagic vacuole
symbiont-mediated perturbation of host synaptic transmission (GO:0044758)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts synaptic transmission, the communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.
Synonyms: modulation by symbiont of host synaptic transmission; regulation by symbiont of host synaptic transmission
symbiont-mediated perturbation of host cholinergic synaptic transmission (GO:0044760)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts cholinergic synaptic transmission, the communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
Synonyms: modulation by symbiont of host cholinergic synaptic transmission; regulation by symbiont of host cholinergic synaptic transmission
symbiont-mediated suppression of host cholinergic synaptic transmission (GO:0044761)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the normal execution of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
Synonyms: negative regulation by symbiont of host cholinergic synaptic transmission
symbiont-mediated suppression of host neurotransmitter secretion (GO:0044762)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the regulated release of a neurotransmitter from a cell in its host organism.
Synonyms: negative regulation by symbiont of host neurotransmitter secretion
obsolete multi-organism cellular process (GO:0044764)
Namespace: biological_process
Definition: OBSOLETE. Any process that is carried out at the cellular level which involves another organism of the same or different species.
Comment: This term was obsoleted because it represents an unnecessary grouping class.
obsolete multi-organism transport (GO:0044766)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
Comment: This term was obsoleted because there is no evidence that this process exists.
ATPase activity, coupled to transmembrane movement of ions, rotational mechanism (GO:0044769)
Namespace: molecular_function
Definition: Enables the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.
cell cycle phase transition (GO:0044770)
Namespace: biological_process
Definition: The cell cycle process by which a cell commits to entering the next cell cycle phase.
Synonyms: cell cycle transition
meiotic cell cycle phase transition (GO:0044771)
Namespace: biological_process
Definition: The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.
Synonyms: cell cycle transition
mitotic cell cycle phase transition (GO:0044772)
Namespace: biological_process
Definition: The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
mitotic DNA damage checkpoint signaling (GO:0044773)
Namespace: biological_process
Definition: A signal transduction process involved in mitotic DNA damage checkpoint.
Synonyms: intracellular signal transduction pathway involved in mitotic DNA damage checkpoint; intracellular signaling cascade involved in mitotic DNA damage checkpoint; intracellular signaling pathway involved in mitotic DNA damage checkpoint; mitotic DNA damage checkpoint; signal transduction involved in mitotic DNA damage checkpoint
mitotic DNA integrity checkpoint signaling (GO:0044774)
Namespace: biological_process
Definition: A signaling process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during mitosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
Synonyms: intracellular signal transduction involved in mitotic cell cycle G2/M transition decatenation checkpoint; intracellular signal transduction involved in topo II checkpoint; intracellular signal transduction pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint; intracellular signal transduction pathway involved in mitotic DNA integrity checkpoint; intracellular signal transduction pathway involved in topo II checkpoint; intracellular signal transduction pathway involved in topoisomerase II checkpoint; intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint; intracellular signaling cascade involved in mitotic DNA integrity checkpoint; intracellular signaling cascade involved in topo II checkpoint; intracellular signaling chain involved in mitotic cell cycle G2/M transition decatenation checkpoint; intracellular signaling chain involved in mitotic DNA integrity checkpoint; intracellular signaling pathway involved in mitotic cell cycle G2/M transition decatenation checkpoint; intracellular signaling pathway involved in mitotic DNA integrity checkpoint; intracellular signaling pathway involved in topo II checkpoint; intracellular signaling pathway involved in topoisomerase II checkpoint; mitotic cell cycle G2/M transition decatenation checkpoint; mitotic DNA integrity checkpoint; signal transduction involved in mitotic DNA integrity checkpoint; signal transduction via intracellular signaling cascade involved in mitotic cell cycle G2/M transition decatenation checkpoint; signal transduction via intracellular signaling cascade involved in topo II checkpoint
DNA polymerase III, beta sliding clamp processivity factor complex (GO:0044775)
Namespace: cellular_component
Definition: A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.
DNA polymerase III, core complex (GO:0044776)
Namespace: cellular_component
Definition: The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.
meiotic DNA integrity checkpoint signaling (GO:0044778)
Namespace: biological_process
Definition: A signal transduction process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA during meiosis. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
Synonyms: meiotic DNA integrity checkpoint
meiotic spindle checkpoint signaling (GO:0044779)
Namespace: biological_process
Definition: A signal transduction process that contributes to a cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.
Synonyms: intracellular signal transduction involved in meiotic spindle checkpoint; intracellular signal transduction pathway involved in meiotic spindle checkpoint; intracellular signaling cascade involved in meiotic spindle checkpoint; intracellular signaling pathway involved in meiotic spindle checkpoint; meiotic spindle checkpoint
bacterial-type flagellum assembly (GO:0044780)
Namespace: biological_process
Definition: The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
Synonyms: bacterial flagellum assembly
bacterial-type flagellum organization (GO:0044781)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
cilium organization (GO:0044782)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
Synonyms: microtubule-based flagellum organization
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
metaphase/anaphase transition of cell cycle (GO:0044784)
Namespace: biological_process
Definition: The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.
metaphase/anaphase transition of meiotic cell cycle (GO:0044785)
Namespace: biological_process
Definition: The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.
Synonyms: meiotic metaphase/anaphase transition
cell cycle DNA replication (GO:0044786)
Namespace: biological_process
Definition: The DNA-dependent DNA replication that takes place as part of the cell cycle.