LiteFold/GO huggingface dataset:
oxytocin production (GO:0036162)
Namespace: biological_process
Definition: The appearance of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG, due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior. It also acts as a neurotransmitter in the brain.
Synonyms: oxytocin biosynthesis; oxytocin secretion
Comment: Note that this term is intended for use when a gene product is seen to cause apparent increases in intracellular or extracellular oxytocin levels, without specific regard as to whether the increase is due to increased biosynthesis, increased secretion of preexisting oxytocin molecules, or increased conversion from precursor molecules.
obsolete 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity (GO:0036163)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 4-hydroxy-3-methoxy-5-(all-trans-hexaprenyl)benzoate + H+ = 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2.
Comment: This term was obsoleted because it represents a specific substrate of GO:0120539 '4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity'.
invasive growth in response to heat (GO:0036165)
Namespace: biological_process
Definition: The growth of colonies in filamentous chains of cells as a result of an increase in temperature.
Synonyms: invasive growth in response to elevated temperature; invasive growth in response to high temperature; invasive growth in response to temperature stimulus
phenotypic switching (GO:0036166)
Namespace: biological_process
Definition: A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
Synonyms: phenotypic dimorphism
Comment: Mating type switching is not considered a type of phenotypic switching: for mating type switching, consider instead annotating to 'mating type switching ; GO:0007533'.
obsolete phenotypic switching in response to host (GO:0036167)
Namespace: biological_process
Definition: OBSOLETE. A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
Comment: This term was obsoleted because it represents the same process as phenotypic switching ; GO:0036166, but under a specific condition.
filamentous growth of a population of unicellular organisms in response to heat (GO:0036168)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.
obsolete 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity (GO:0036169)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.
Comment: The reason for obsoletion is that this term is equivalent to 4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity.
filamentous growth of a population of unicellular organisms in response to starvation (GO:0036170)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
filamentous growth of a population of unicellular organisms in response to chemical stimulus (GO:0036171)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
thiamine salvage (GO:0036172)
Namespace: biological_process
Definition: A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.
thiosulfate binding (GO:0036173)
Namespace: molecular_function
Definition: Binding to a thiosulfate, a sulfur oxide that has formula O3S2.
butane monooxygenase activity (GO:0036174)
Namespace: molecular_function
Definition: Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.
Synonyms: sBMO; soluble butane monooxygenase
ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor (GO:0036175)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O = ribonucleoside diphosphate + glutaredoxin.
filamentous growth of a population of unicellular organisms in response to pH (GO:0036177)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
filamentous growth of a population of unicellular organisms in response to neutral pH (GO:0036178)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
osteoclast maturation (GO:0036179)
Namespace: biological_process
Definition: A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.
Synonyms: chondroclast maturation
filamentous growth of a population of unicellular organisms in response to biotic stimulus (GO:0036180)
Namespace: biological_process
Definition: The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
protein localization to linear element (GO:0036181)
Namespace: biological_process
Definition: A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.
Synonyms: protein localisation to linear element
asperthecin metabolic process (GO:0036182)
Namespace: biological_process
Definition: The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
Synonyms: asperthecin metabolism
asperthecin catabolic process (GO:0036183)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
Synonyms: asperthecin breakdown; asperthecin catabolism; asperthecin degradation
asperthecin biosynthetic process (GO:0036184)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
Synonyms: asperthecin biosynthesis; asperthecin formation; asperthecin synthesis
13-lipoxin reductase activity (GO:0036185)
Namespace: molecular_function
Definition: Catalysis of the reaction: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H+ = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD+.
early phagosome membrane (GO:0036186)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an early phagosome.
Synonyms: early phagocytic vesicle membrane
cell growth mode switching, budding to filamentous (GO:0036187)
Namespace: biological_process
Definition: The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.
Synonyms: yeast to hyphal transition
indole-2-monooxygenase activity (GO:0036190)
Namespace: molecular_function
Definition: Catalysis of the reaction: indole + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase].
2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity (GO:0036193)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase] = DIBOA + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
muscle cell projection (GO:0036194)
Namespace: cellular_component
Definition: A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
Synonyms: muscle arm; myocyte projection; myopodia
zymosterol metabolic process (GO:0036196)
Namespace: biological_process
Definition: The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
zymosterol biosynthetic process (GO:0036197)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
Synonyms: zymosterol anabolism; zymosterol biosynthesis; zymosterol formation; zymosterol synthesis
dTMP salvage (GO:0036198)
Namespace: biological_process
Definition: Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.
Synonyms: deoxythymidine monophosphate biosynthesis via salvage pathway; dTMP biosynthesis via salvage pathway
cholest-4-en-3-one 26-monooxygenase activity (GO:0036199)
Namespace: molecular_function
Definition: Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
3-ketosteroid 9-alpha-monooxygenase activity (GO:0036200)
Namespace: molecular_function
Definition: Catalysis of the reaction: androsta-1,4-diene-3,17-dione + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].
Synonyms: 3-ketosteroid 9alpha-hydroxylase activity; KshAB activity
ent-isokaurene C2-hydroxylase activity (GO:0036201)
Namespace: molecular_function
Definition: Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.
ent-cassa-12,15-diene 11-hydroxylase activity (GO:0036202)
Namespace: molecular_function
Definition: Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.
Synonyms: ent-cassadiene C11alpha-hydroxylase activity
taxoid 14-beta-hydroxylase activity (GO:0036203)
Namespace: molecular_function
Definition: Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.
histone catabolic process (GO:0036205)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
Synonyms: histone protein catabolic process
Comment: This term was created even though it describes a process relating to a group of gene products, because histones are highly conserved proteins that are essential components of cellular chromatin in eukaryotic cells.
obsolete regulation of histone gene expression (GO:0036206)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
Synonyms: regulation of expression of histone-encoding gene
Comment: This term was obsoleted because it refers to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.
obsolete positive regulation of histone gene expression (GO:0036207)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
Synonyms: activation of histone gene expression; positive regulation of expression of histone-encoding gene; up-regulation of histone gene expression; upregulation of histone gene expression
Comment: This term was obsoleted because it refers to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.
obsolete negative regulation of histone gene expression (GO:0036208)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
Synonyms: down-regulation of histone gene expression; downregulation of histone gene expression; inhibition of histone gene expression; negative regulation of expression of histone-encoding gene
Comment: This term was obsoleted because the gene product should be captured as an annotation extension using 'has input'.
9beta-pimara-7,15-diene oxidase activity (GO:0036209)
Namespace: molecular_function
Definition: Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].
Synonyms: 9-beta-stemod-13(17)-ene oxidase activity
protein modification process (GO:0036211)
Namespace: biological_process
Definition: The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
Synonyms: cellular protein modification process; process resulting in protein modification; protein modification
obsolete contractile ring maintenance (GO:0036212)
Namespace: biological_process
Definition: OBSOLETE. The process in which the contractile ring is maintained, typically in response to an internal or external cue.
Comment: The reason for obsoletion is that this represents a phenotype.
obsolete contractile ring localization (GO:0036214)
Namespace: biological_process
Definition: OBSOLETE. The process in which a contractile ring is positioned or maintained in a specific location.
Comment: This term was an unnecessary grpuping term.
response to stem cell factor (GO:0036215)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
Synonyms: response to hematopoietic growth factor KL; response to KIT ligand; response to SCF; response to stem cell factor stimulus
cellular response to stem cell factor stimulus (GO:0036216)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
Synonyms: cellular response to hematopoietic growth factor KL; cellular response to KIT ligand; cellular response to KITLG; cellular response to SCF
dTTP diphosphatase activity (GO:0036218)
Namespace: molecular_function
Definition: Catalysis of the reaction: dTTP + H2O = dTMP + H+ + diphosphate.
Synonyms: dTTP pyrophosphatase activity
GTP diphosphatase activity (GO:0036219)
Namespace: molecular_function
Definition: Catalysis of the reaction: GTP + H2O = GMP + H+ + diphosphate.
Synonyms: GTP diphosphohydrolase (diphosphate-forming); guanosine 5'-triphosphate pyrophosphohydrolase; GTP diphosphohydrolase activity; GTP pyrophosphatase activity
ITP diphosphatase activity (GO:0036220)
Namespace: molecular_function
Definition: Catalysis of the reaction: ITP + H2O = IMP + H+ + diphosphate.
Synonyms: inosine-5'-triphosphate pyrophosphohydrolase activity; ITP pyrophosphatase activity
UTP diphosphatase activity (GO:0036221)
Namespace: molecular_function
Definition: Catalysis of the reaction: UTP + H2O = UMP + H+ + diphosphate.
Synonyms: uridine triphosphate pyrophosphohydrolase activity
XTP diphosphatase activity (GO:0036222)
Namespace: molecular_function
Definition: Catalysis of the reaction: XTP + H2O = XMP + H+ + diphosphate.
Synonyms: hypoxanthine/xanthine dNTP pyrophosphatase; XTP pyrophosphohydrolase activity; XTP/dITP diphosphatase; XTPase activity
Comment: While XTP is not produced by cells, deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP, and dXTP. XTPase contributes to the removal of these abnormal bases from the cellular pool of nucleotide triphosphates.
cellular response to adenine starvation (GO:0036223)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.
Synonyms: cellular response to adenine deprivation
pairing center (GO:0036224)
Namespace: cellular_component
Definition: A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.
Synonyms: homolog recognition region
cellular response to vitamin B1 starvation (GO:0036225)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).
Synonyms: cellular response to thiamin starvation; cellular response to vitamin B1 deprivation
obsolete mitotic cell cycle arrest in response to glucose starvation (GO:0036226)
Namespace: biological_process
Definition: OBSOLETE. The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M) as a result of deprivation of glucose.
Synonyms: cell cycle arrest in response to glucose starvation
Comment: This term was made obsolete because it is superfluous, as only the more specific 'mitotic G2 cell cycle arrest in response to glucose starvation' has been observed.
mitotic G2 cell cycle arrest in response to glucose starvation (GO:0036227)
Namespace: biological_process
Definition: The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.
granulocyte activation (GO:0036230)
Namespace: biological_process
Definition: The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
obsolete deglucuronidation (GO:0036234)
Namespace: biological_process
Definition: OBSOLETE. The removal of glucuronic acid from a conjugated substrate.
Comment: The reason for obsoletion is that the term represents a molecular function.
obsolete acyl deglucuronidation (GO:0036235)
Namespace: biological_process
Definition: OBSOLETE. The removal of glucuronic acid from an acyl-glucuronide.
Comment: The reason for obsoletion is that the term represents a molecular function.
obsolete acyl glucuronidation (GO:0036236)
Namespace: biological_process
Definition: OBSOLETE. The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).
Comment: The reason for obsoletion is that the term represents a molecular function.
acyl-glucuronidase activity (GO:0036237)
Namespace: molecular_function
Definition: Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.
Synonyms: acyl-glucuronide deglucuronidation activity
gallate dioxygenase activity (GO:0036238)
Namespace: molecular_function
Definition: Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.
taxoid 7beta-hydroxylase activity (GO:0036239)
Namespace: molecular_function
Definition: Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O. Also converts 2alpha-hydroxytaxusin to 2alpha,7beta-dihydroxytaxusin.
septal periplasm (GO:0036240)
Namespace: cellular_component
Definition: The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.
Synonyms: cell wall-enclosed septal periplasm
obsolete glutamate catabolic process to 4-hydroxybutyrate (GO:0036241)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.
Comment: This term was obsoleted because it represents a specific instance of a pathway that should be captured as a GO-CAM model.
obsolete glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity (GO:0036242)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.
Comment: The reason for obsoletion is that this term was added in error (unnecessary specificity, these are steps in a single pathway)
succinate-semialdehyde dehydrogenase (NADP+) activity (GO:0036243)
Namespace: molecular_function
Definition: Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.
Synonyms: NADP-dependent succinate-semialdehyde dehydrogenase activity; succinate semialdehyde:NADP+ oxidoreductase activity; succinic semialdehyde dehydrogenase (NADP+) activity; succinyl semialdehyde dehydrogenase (NADP+) activity
Comment: This function is similar to EC:1.2.1.24 [succinate-semialdehyde dehydrogenase (NAD+)], and EC:1.2.1.16 [succinate-semialdehyde dehydrogenase (NAD(P)+)], but is specific for NADP+.
cellular response to neutral pH (GO:0036244)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.