LiteFold/GO huggingface dataset:
nuclear pore cytoplasmic filaments (GO:0044614)
Namespace: cellular_component
Definition: Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.
Synonyms: cytoplasmic fibers of the NPC; cytoplasmic fibers of the nuclear pore complex
nuclear pore nuclear basket (GO:0044615)
Namespace: cellular_component
Definition: A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
venom-mediated paralysis (GO:0044616)
Namespace: biological_process
Definition: A process in which an organism induces paralysis in another organism via the action of a venom. Paralysis is the loss of the ability to voluntarily control muscles. This can occur by blocking nerve signals at the neuromuscular junction or by directly interfering with muscle contraction.
Synonyms: envenomation resulting in paralysis in another organism; modulation of relaxation of muscle in another organism; modulation of relaxation of muscle in other organism; regulation of relaxation of muscle in other organism
venom-mediated smooth muscle relaxation (GO:0044617)
Namespace: biological_process
Definition: A process in which an organism initiates, promotes, or enhances the relaxation of smooth muscle in another organism via the action of a venom.
Synonyms: modulation of relaxation of smooth muscle in another organism; modulation of relaxation of smooth muscle in other organism; regulation of relaxation of smooth muscle in other organism
obsolete venom-mediated relaxation of uterine smooth muscle (GO:0044619)
Namespace: biological_process
Definition: OBSOLETE. The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.
Synonyms: envenomation resulting in uterine smooth muscle relaxation in another organism; positive regulation of relaxation of uterine smooth muscle in other organism
Comment: This term was obsoleted because it represents an experimental system.
ACP phosphopantetheine attachment site binding (GO:0044620)
Namespace: molecular_function
Definition: Binding to the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).
obsolete modulation of cell migration in another organism (GO:0044621)
Namespace: biological_process
Definition: OBSOLETE. The process in which an organism effects a change in the process of cell migration in a second organism.
Synonyms: envenomation resulting in modulation of cell migration in another organism; envenomation resulting in modulation of cell migration in other organism; envenomation resulting in regulation of cell migration in other organism; modulation of cell migration in other organism; regulation of cell migration in other organism
Comment: This term was obsoleted because it is too general.
obsolete negative regulation of cell migration in another organism (GO:0044622)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.
Synonyms: envenomation resulting in negative regulation of cell migration in another organism; envenomation resulting in negative regulation of cell migration in other organism; negative regulation of cell migration in other organism
Comment: This term was obsoleted because it is too general.
obsolete modulation of complement activation, classical pathway in another organism (GO:0044627)
Namespace: biological_process
Definition: OBSOLETE. A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism.
Synonyms: modulation of complement activation, classical pathway in other organism; regulation of complement activation, classical pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete positive regulation of complement activation, classical pathway in another organism (GO:0044628)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
Synonyms: positive regulation of complement activation, classical pathway in other organism
Comment: This term has been obsoleted because this process does not exist.
obsolete negative regulation of complement activation, classical pathway in another organism (GO:0044629)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
Synonyms: negative regulation of complement activation, classical pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete modulation of complement activation, lectin pathway in another organism (GO:0044630)
Namespace: biological_process
Definition: OBSOLETE. A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism.
Synonyms: modulation of complement activation, lectin pathway in other organism; regulation of complement activation, lectin pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete positive regulation of complement activation, lectin pathway in another organism (GO:0044631)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism.
Synonyms: positive regulation of complement activation, lectin pathway in other organism
Comment: This term was obsoleted because this process does not exist.
obsolete modulation of complement activation, alternative pathway in another organism (GO:0044633)
Namespace: biological_process
Definition: OBSOLETE. A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.
Synonyms: modulation of complement activation, alternative pathway in other organism; regulation of complement activation, alternative pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete negative regulation of complement activation, alternative pathway in another organism (GO:0044634)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
Synonyms: negative regulation of complement activation, alternative pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete positive regulation of complement activation, alternative pathway in another organism (GO:0044635)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
Synonyms: positive regulation of complement activation, alternative pathway in other organism
Comment: This term was obsoleted because this process does not exist.
obsolete envenomation resulting in negative regulation of complement activation, classical pathway in another organism (GO:0044637)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism.
Synonyms: envenomation resulting in negative regulation of complement activation, classical pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete envenomation resulting in negative regulation of complement activation, lectin pathway in another organism (GO:0044640)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism.
Synonyms: envenomation resulting in negative regulation of complement activation, lectin pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete envenomation resulting in positive regulation of complement activation, lectin pathway in another organism (GO:0044641)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism.
Synonyms: envenomation resulting in positive regulation of complement activation, lectin pathway in other organism
Comment: This term was obsoleted because this process does not exist.
obsolete envenomation resulting in modulation of complement activation, alternative pathway in another organism (GO:0044642)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism.
Synonyms: envenomation resulting in modulation of complement activation, alternative pathway in other organism; envenomation resulting in regulation of complement activation, alternative pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete envenomation resulting in negative regulation of complement activation, alternative pathway in another organism (GO:0044644)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.
Synonyms: envenomation resulting in negative regulation of complement activation, alternative pathway in other organism
Comment: This term was obsoleted because it is too specific.
obsolete envenomation resulting in modulation of complement activation in another organism (GO:0044646)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism.
Synonyms: envenomation resulting in modulation of complement activation in other organism; envenomation resulting in regulation of complement activation in other organism
Comment: This term was obsoleted because it is too specific.
host-symbiont bicellular tight junction (GO:0044647)
Namespace: cellular_component
Definition: An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.
Synonyms: host-parasite tight junction; host-pathogen tight junction
obsolete histone H3-K4 dimethylation (GO:0044648)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.
Comment: This term was obsoleted because it represents a molecular function.
adhesion of symbiont to host cell (GO:0044650)
Namespace: biological_process
Definition: The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.
adhesion of symbiont to host endothelial cell (GO:0044652)
Namespace: biological_process
Definition: The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
obsolete dextrin alpha-glucosidase activity (GO:0044653)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.
Comment: This term was obsoleted because it represents a specific substrate of alpha-1,4-glucosidase activity ; GO:0004558.
phagosome reneutralization (GO:0044655)
Namespace: biological_process
Definition: Any process that increases the pH of the phagosome, corresponding to a decrease in hydrogen ion concentration, as part of the process of phagosome maturation.
Synonyms: phagosomal reneutralization; phagosome pH elevation
regulation of post-lysosomal vacuole size (GO:0044656)
Namespace: biological_process
Definition: Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.
Synonyms: regulation of post-lysosome size; regulation of postlysosomal vacuole size; regulation of postlysosome vacuole size
obsolete pore formation in membrane of other organism during symbiotic interaction (GO:0044657)
Namespace: biological_process
Definition: OBSOLETE. The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction.
Comment: This term was obsoleted because it represents an unnecessary grouping class.
symbiont-mediated pore formation in host plasma membrane (GO:0044658)
Namespace: biological_process
Definition: The disruption of host plasma membrane integrity by formation of a pore, resulting in deregulated ion homeostasis, and cellular dysfunction that can result in cell death.
Synonyms: pore formation in host plasma membrane; pore formation in membrane of host by symbiont
viral release from host cell by cytolysis (GO:0044659)
Namespace: biological_process
Definition: The dissemination of mature viral particles from a host cell by the rupture of cell membranes and the loss of cytoplasm.
Synonyms: cytolysis by virus of host cell; lytic viral life cycle; lytic viral release; viral exit from host cell by cytolysis; viral release by cell lysis; viral release by host cell lysis
establishment or maintenance of cell type involved in phenotypic switching (GO:0044663)
Namespace: biological_process
Definition: A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
obsolete reversion of cell type to default state involved in phenotypic switching (GO:0044664)
Namespace: biological_process
Definition: OBSOLETE. The cellular process of the reversion of cells to their original cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
Comment: This term was made obsolete because it is ambiguous.
MLL1/2 complex (GO:0044665)
Namespace: cellular_component
Definition: A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.
Synonyms: Trx-containing complex
MLL3/4 complex (GO:0044666)
Namespace: cellular_component
Definition: A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.
Synonyms: Trr/COMPASS-like complex
(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity (GO:0044667)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).
Synonyms: (R)-carnitine:gamma-butyrobetaine antiporter activity; L-carnitine:4-(trimethylammonio)butanoate antiporter activity; L-carnitine:gamma-butyrobetaine antiporter activity
sodium:malonate symporter activity (GO:0044668)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).
sodium:galactoside symporter activity (GO:0044669)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).
sorocarp spore cell differentiation (GO:0044671)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex (GO:0044673)
Namespace: cellular_component
Definition: A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.
Synonyms: FO-synthase complex
methyl coenzyme M reductase complex (GO:0044674)
Namespace: cellular_component
Definition: A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.
formyl-methanofuran dehydrogenase (tungsten enzyme) complex (GO:0044675)
Namespace: cellular_component
Definition: A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
formyl-methanofuran dehydrogenase (molybdenum enzyme) complex (GO:0044676)
Namespace: cellular_component
Definition: A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex (GO:0044677)
Namespace: cellular_component
Definition: A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.
Synonyms: 5-methyl-5,6,7,8-tetrahydromethanopterin:2-mercaptoethane sulfonate 2-methyltransferase complex; coenzyme M methyltransferase complex; methyl-H4MPT; N5-methyltetrahydromethanopterin-coenzyme M methyltransferase complex
CoB-CoM heterodisulfide reductase complex (GO:0044678)
Namespace: cellular_component
Definition: A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.
Synonyms: coenzyme M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase complex; hydrogen:coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide oxidoreductase complex
methanophenazine reducing hydrogenase complex (GO:0044679)
Namespace: cellular_component
Definition: A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.
sulfopyruvate decarboxylase complex (GO:0044681)
Namespace: cellular_component
Definition: A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.
GTP cyclohydrolase IV activity (GO:0044682)
Namespace: molecular_function
Definition: Catalysis of the reaction: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.
Synonyms: archaeal-specific GTP cyclohydrolase activity; Fe(2+)-dependent archaeal-specific GTP cyclohydrolase activity; MptA activity
methylthiol:coenzyme M methyltransferase activity (GO:0044683)
Namespace: molecular_function
Definition: Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.
Synonyms: methylthiol:coenzyme M methyl transferase activity
Comment: This reaction is achieved by the catalysis of two successive steps carried out by the same enzyme - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, EC:2.1.1.90, methanol-corrinoid protein Co-methyltransferase, and EC:2.1.1.246, methylated methanol-specific corrinoid protein:coenzyme M methyltransferase). The cobalt is oxidized during methylation from the Co(I) state to the Co(III) state, and is reduced back to the Co(I) form during demethylation.
dihydromethanopterin reductase activity (GO:0044684)
Namespace: molecular_function
Definition: Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.
obsolete tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity (GO:0044685)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
cysteate synthase activity (GO:0044686)
Namespace: molecular_function
Definition: Catalysis of the reaction: O-phospho-L-serine + sulfite + H+ = L-cysteate + phosphate.
7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity (GO:0044688)
Namespace: molecular_function
Definition: Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.
tooth eruption (GO:0044691)
Namespace: biological_process
Definition: The tooth development process in which the teeth enter the mouth and become visible.
exoribonuclease activator activity (GO:0044692)
Namespace: molecular_function
Definition: Binds to and increases the activity of an exoribonuclease.
trehalose:proton symporter activity (GO:0044693)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).
Synonyms: trehalose:hydrogen symporter activity