LiteFold/GO huggingface dataset:
sphere organelle (GO:0071601)
Namespace: cellular_component
Definition: A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.
phytosphingosine biosynthetic process (GO:0071602)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.
Synonyms: phytosphingosine anabolism; phytosphingosine biosynthesis; phytosphingosine formation; phytosphingosine synthesis
endothelial cell-cell adhesion (GO:0071603)
Namespace: biological_process
Definition: The attachment of an endothelial cell to another endothelial cell via adhesion molecules.
transforming growth factor beta production (GO:0071604)
Namespace: biological_process
Definition: The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.
Synonyms: TGF-B production; TGF-beta production; TGFb production; TGFbeta production; transforming growth factor-beta production; transforming growth factor-beta secretion
monocyte chemotactic protein-1 production (GO:0071605)
Namespace: biological_process
Definition: The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL2 production; MCP-1 production
chemokine (C-C motif) ligand 4 production (GO:0071606)
Namespace: biological_process
Definition: The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL4 production; macrophage inflammatory protein production; MIP-1b production
macrophage inflammatory protein-1 gamma production (GO:0071607)
Namespace: biological_process
Definition: The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL9 production; chemokine (C-C motif) ligand 9 production; MIP-1g production
macrophage inflammatory protein-1 alpha production (GO:0071608)
Namespace: biological_process
Definition: The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL3 production; chemokine (C-C motif) ligand 3 production; macrophage inflammatory protein production; MIP-1a production
granulocyte colony-stimulating factor production (GO:0071611)
Namespace: biological_process
Definition: The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: colony stimulating factor 3 (granulocyte) production; CSF3 production; filgrastim production; G-CSF production; granulocyte colony stimulating factor production; lenograstim production; pluripoietin production
IP-10 production (GO:0071612)
Namespace: biological_process
Definition: The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: chemokine (C-C motif) ligand 10 production; CXCL10 production
granzyme B production (GO:0071613)
Namespace: biological_process
Definition: The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
linoleic acid epoxygenase activity (GO:0071614)
Namespace: molecular_function
Definition: Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.
Synonyms: linoleic acid monooxygenase activity
obsolete oxidative deethylation (GO:0071615)
Namespace: biological_process
Definition: OBSOLETE. The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.
Comment: This term was obsoleted because it represents a molecular function.
lysophospholipid acyltransferase activity (GO:0071617)
Namespace: molecular_function
Definition: Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.
lysophosphatidylethanolamine acyltransferase activity (GO:0071618)
Namespace: molecular_function
Definition: Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.
obsolete phosphorylation of RNA polymerase II C-terminal domain serine 2 residues (GO:0071619)
Namespace: biological_process
Definition: OBSOLETE. The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
Comment: This term was obsoleted because it represents a molecular function.
obsolete phosphorylation of RNA polymerase II C-terminal domain serine 5 residues (GO:0071620)
Namespace: biological_process
Definition: OBSOLETE. The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).
Comment: This term was obsoleted because it represents a molecular function.
granulocyte chemotaxis (GO:0071621)
Namespace: biological_process
Definition: The movement of a granulocyte in response to an external stimulus.
regulation of granulocyte chemotaxis (GO:0071622)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
negative regulation of granulocyte chemotaxis (GO:0071623)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
positive regulation of granulocyte chemotaxis (GO:0071624)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
vocalization behavior (GO:0071625)
Namespace: biological_process
Definition: The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
Synonyms: vocalisation behaviour
mastication (GO:0071626)
Namespace: biological_process
Definition: The process of biting and mashing food with the teeth prior to swallowing.
Synonyms: chewing
obsolete intrinsic component of fungal-type vacuolar membrane (GO:0071628)
Namespace: cellular_component
Definition: OBSOLETE. The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
cytoplasm protein quality control by the ubiquitin-proteasome system (GO:0071629)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.
Synonyms: cytoplasm-associated proteasomal ubiquitin-dependent protein breakdown; cytoplasm-associated proteasomal ubiquitin-dependent protein catabolism; cytoplasm-associated proteasomal ubiquitin-dependent protein degradation; ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome
Comment: See also the biological process terms 'unfolded protein response ; GO:0030968' and 'retrograde protein transport, ER to cytosol ; GO:0030970'.
nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630)
Namespace: biological_process
Definition: A protein quality control pathway that results in the breakdown of misfolded, damaged or unassembled proteins via a mechanism in which the proteins are ubiquitinated, and then targeted to nuclear proteasomes for degradation.
Synonyms: nucleus-associated proteasomal ubiquitin-dependent protein breakdown; nucleus-associated proteasomal ubiquitin-dependent protein catabolism; nucleus-associated proteasomal ubiquitin-dependent protein degradation; ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
mating pheromone secretion involved in positive regulation of conjugation with cellular fusion (GO:0071631)
Namespace: biological_process
Definition: The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that positively regulates a conjugation process that results in the union of cellular and genetic information from compatible mating types.
Synonyms: mating-type pheromone secretion involved in conjugation with cellular fusion; peptide pheromone export involved in positive regulation of conjugation with cellular fusion
optomotor response (GO:0071632)
Namespace: biological_process
Definition: Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.
obsolete dihydroceramidase activity (GO:0071633)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine.
Comment: The reason for obsoletion is that this term represents a specific substrate of GO:0017040 N-acylsphingosine amidohydrolase activity.
regulation of transforming growth factor beta production (GO:0071634)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms: regulation of TGF-B production; regulation of TGF-beta production; regulation of TGFB production; regulation of TGFbeta production; regulation of transforming growth factor-beta production; regulation of transforming growth factor-beta secretion
negative regulation of transforming growth factor beta production (GO:0071635)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms: negative regulation of TGF-B production; negative regulation of TGF-beta production; negative regulation of TGFB production; negative regulation of TGFbeta production; negative regulation of transforming growth factor-beta production; negative regulation of transforming growth factor-beta secretion
positive regulation of transforming growth factor beta production (GO:0071636)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
Synonyms: positive regulation of TGF-B production; positive regulation of TGF-beta production; positive regulation of TGFB production; positive regulation of TGFbeta production; positive regulation of transforming growth factor-beta production; positive regulation of transforming growth factor-beta secretion
regulation of monocyte chemotactic protein-1 production (GO:0071637)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.
Synonyms: regulation of CCL2 production; regulation of MCP-1 production
negative regulation of monocyte chemotactic protein-1 production (GO:0071638)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.
Synonyms: negative regulation of CCL2 production; negative regulation of MCP-1 production
positive regulation of monocyte chemotactic protein-1 production (GO:0071639)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.
Synonyms: positive regulation of CCL2 production; positive regulation of MCP-1 production
regulation of macrophage inflammatory protein 1 alpha production (GO:0071640)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
Synonyms: regulation of CCL3 production; regulation of chemokine (C-C motif) ligand 3 production; regulation of macrophage inflammatory protein production; regulation of MIP-1a production
negative regulation of macrophage inflammatory protein 1 alpha production (GO:0071641)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
Synonyms: negative regulation of CCL3 production; negative regulation of chemokine (C-C motif) ligand 3 production; negative regulation of macrophage inflammatory protein production; negative regulation of MIP-1a production
positive regulation of macrophage inflammatory protein 1 alpha production (GO:0071642)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
Synonyms: positive regulation of CCL3 production; positive regulation of chemokine (C-C motif) ligand 3 production; positive regulation of macrophage inflammatory protein production; positive regulation of MIP-1a production
regulation of chemokine (C-C motif) ligand 4 production (GO:0071643)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
Synonyms: regulation of CCL4 production; regulation of macrophage inflammatory protein production; regulation of MIP-1b production
negative regulation of chemokine (C-C motif) ligand 4 production (GO:0071644)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
Synonyms: negative regulation of CCL4 production; negative regulation of macrophage inflammatory protein production; negative regulation of MIP-1b production
positive regulation of chemokine (C-C motif) ligand 4 production (GO:0071645)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
Synonyms: positive regulation of CCL4 production; positive regulation of macrophage inflammatory protein production; positive regulation of MIP-1b production
regulation of macrophage inflammatory protein-1 gamma production (GO:0071646)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
Synonyms: regulation of CCL9 production; regulation of chemokine (C-C motif) ligand 9 production; regulation of MIP-1g production
negative regulation of macrophage inflammatory protein-1 gamma production (GO:0071647)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
Synonyms: negative regulation of CCL9 production; negative regulation of chemokine (C-C motif) ligand 9 production; negative regulation of MIP-1g production
positive regulation of macrophage inflammatory protein-1 gamma production (GO:0071648)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
Synonyms: positive regulation of CCL9 production; positive regulation of chemokine (C-C motif) ligand 9 production; positive regulation of MIP-1g production
regulation of chemokine (C-C motif) ligand 5 production (GO:0071649)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
Synonyms: regulation of CCL5 production; regulation of RANTES production; regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production
negative regulation of chemokine (C-C motif) ligand 5 production (GO:0071650)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
Synonyms: negative regulation of CCL5 production; negative regulation of RANTES production; negative regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production
regulation of chemokine (C-C motif) ligand 1 production (GO:0071652)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
Synonyms: regulation of CCL1 production; regulation of T cell activation 3 production; regulation of TCA-3 production
negative regulation of chemokine (C-C motif) ligand 1 production (GO:0071653)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
Synonyms: negative regulation of CCL1 production; negative regulation of T cell activation 3 production; negative regulation of TCA-3 production
positive regulation of chemokine (C-C motif) ligand 1 production (GO:0071654)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
Synonyms: positive regulation of CCL1 production; positive regulation of T cell activation 3 production; positive regulation of TCA-3 production
regulation of granulocyte colony-stimulating factor production (GO:0071655)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
Synonyms: regulation of colony stimulating factor 3 (granulocyte) production; regulation of CSF3 production; regulation of filgrastim production; regulation of G-CSF production; regulation of granulocyte colony stimulating factor production; regulation of lenograstim production; regulation of pluripoietin production
negative regulation of granulocyte colony-stimulating factor production (GO:0071656)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.
Synonyms: negative regulation of colony stimulating factor 3 (granulocyte) production; negative regulation of CSF3 production; negative regulation of filgrastim production; negative regulation of G-CSF production; negative regulation of granulocyte colony stimulating factor production; negative regulation of lenograstim production; negative regulation of pluripoietin production
positive regulation of granulocyte colony-stimulating factor production (GO:0071657)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
Synonyms: positive regulation of colony stimulating factor 3 (granulocyte) production; positive regulation of CSF3 production; positive regulation of filgrastim production; positive regulation of G-CSF production; positive regulation of granulocyte colony stimulating factor production; positive regulation of lenograstim production; positive regulation of pluripoietin production
regulation of IP-10 production (GO:0071658)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of IP-10.
Synonyms: regulation of chemokine (C-C motif) ligand 10 production; regulation of CXCL10 production
negative regulation of IP-10 production (GO:0071659)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.
Synonyms: negative regulation of chemokine (C-C motif) ligand 10 production; negative regulation of CXCL10 production
positive regulation of IP-10 production (GO:0071660)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of IP-10.
Synonyms: positive regulation of chemokine (C-C motif) ligand 10 production; positive regulation of CXCL10 production
regulation of granzyme B production (GO:0071661)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of production of granzyme B.
negative regulation of granzyme B production (GO:0071662)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.
positive regulation of granzyme B production (GO:0071663)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of granzyme B.
catenin-TCF7L2 complex (GO:0071664)
Namespace: cellular_component
Definition: A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
Synonyms: catenin-TCF4 complex
gamma-catenin-TCF7L2 complex (GO:0071665)
Namespace: cellular_component
Definition: A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
Synonyms: gamma-catenin-TCF4 complex; plakoglobin-TCF4 complex
Slit-Robo signaling complex (GO:0071666)
Namespace: cellular_component
Definition: A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.
Synonyms: Slit-Robo signalling complex
DNA/RNA hybrid binding (GO:0071667)
Namespace: molecular_function
Definition: Binding to a RNA/DNA hybrid.
Synonyms: RNA/DNA hybrid binding
plant-type cell wall assembly (GO:0071668)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.
Synonyms: plant cell wall assembly
smooth muscle cell chemotaxis (GO:0071670)
Namespace: biological_process
Definition: The directed movement of a smooth muscle cell in response to an external stimulus.