LiteFold/GO huggingface dataset:
obsolete DNA-dependent DNA replication DNA ligation (GO:0051104)
Namespace: biological_process
Definition: OBSOLETE. The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.
Synonyms: DNA ligation during DNA-dependent DNA replication; DNA ligation involved in DNA-dependent DNA replication
Comment: The reason for obsoletion is that the term represents a molecular function.
obsolete regulation of DNA ligation (GO:0051105)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
Comment: The reason for obsoletion is that the term represents a molecular function.
obsolete positive regulation of DNA ligation (GO:0051106)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
Synonyms: activation of DNA ligation; stimulation of DNA ligation; up regulation of DNA ligation; up-regulation of DNA ligation; upregulation of DNA ligation
Comment: The reason for obsoletion is that the term represents a molecular function.
obsolete negative regulation of DNA ligation (GO:0051107)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
Synonyms: down regulation of DNA ligation; down-regulation of DNA ligation; downregulation of DNA ligation; inhibition of DNA ligation
Comment: The reason for obsoletion is that the term represents a molecular function.
carnitine-CoA ligase activity (GO:0051108)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.
Synonyms: carnitine synthetase activity; crotonobetaine/carnitine-CoA ligase activity
crotonobetaine-CoA ligase activity (GO:0051109)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-carnitine + ATP + CoA = (R)-carnitinyl-CoA + AMP + diphosphate. Also catalyzes the transfer of CoA to crotonobetaine and gamma-butyrobetaine.
Synonyms: crotonobetaine-CoA synthase activity; crotonobetaine/carnitine-CoA ligase activity
obsolete peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (GO:0051110)
Namespace: biological_process
Definition: OBSOLETE. The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).
Comment: This term was obsoleted because it represents a molecular function.
peptidyl-histidine adenylylation (GO:0051111)
Namespace: biological_process
Definition: The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).
obsolete peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (GO:0051112)
Namespace: biological_process
Definition: OBSOLETE. The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).
Comment: This term was obsoleted because it represents a molecular function.
obsolete enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine (GO:0051113)
Namespace: biological_process
Definition: OBSOLETE. The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).
Comment: This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:15182206.
peptidyl-histidine uridylylation (GO:0051114)
Namespace: biological_process
Definition: The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).
obsolete enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine (GO:0051115)
Namespace: biological_process
Definition: OBSOLETE. The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).
Comment: This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:8794735.
cobaltochelatase activity (GO:0051116)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + Co(2+) + H2O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H+ + phosphate.
Synonyms: CobN-CobST; CobNST; hydrogenobyrinic acid a,c-diamide cobaltochelatase activity; hydrogenobyrinic-acid-a,c-diamide:cobalt cobalt-ligase (ADP-forming)
ATPase binding (GO:0051117)
Namespace: molecular_function
Definition: Binding to an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
glucan endo-1,3-alpha-glucosidase activity (GO:0051118)
Namespace: molecular_function
Definition: Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.
Synonyms: 1,3(1,3;1,4)-alpha-D-glucan 3-glucanohydrolase activity; cariogenanase activity; cariogenase activity; endo-(1->3)-alpha-glucanase activity; endo-1,3-alpha-D-glucanase activity; endo-1,3-alpha-glucanase activity; mutanase activity
sugar transmembrane transporter activity (GO:0051119)
Namespace: molecular_function
Definition: Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
Synonyms: sugar/polyol channel activity
obsolete hepoxilin A3 synthase activity (GO:0051120)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
Comment: The reason for obsoletion is that this term is equivalent to hydroperoxy icosatetraenoate isomerase activity.
obsolete hepoxilin metabolic process (GO:0051121)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
Synonyms: hepoxilin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
hepoxilin biosynthetic process (GO:0051122)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
Synonyms: hepoxilin anabolism; hepoxilin biosynthesis; hepoxilin formation; hepoxilin synthesis
RNA polymerase II preinitiation complex assembly (GO:0051123)
Namespace: biological_process
Definition: The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which may include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH complexes). The PIC engages RNA polymerase II on its DNA template strand and sparks polymerization of the first few RNA nucleotides of the nascent transcript, of which 8 are base-paired with the DNA template within a DNA bubble. PIC assembly may result in a pause step, which marks the end of the PIC assembly and may be followed by promoter clearance (exact synonym: promoter escape). For RNA polymerase II PIC assembly is preceded by the formation of a nucleosome-free region that allows the transcription machinery to access the promoter DNA.
Synonyms: RNA polymerase II transcription PIC biosynthesis; RNA polymerase II transcription PIC formation; RNA polymerase II transcriptional preinitiation complex assembly; RNA polymerase II transcriptional preinitiation complex formation
synaptic assembly at neuromuscular junction (GO:0051124)
Namespace: biological_process
Definition: The assembly of a synapse at a neuromuscular junction.
Synonyms: cholinergic synaptogenesis; synaptic growth at neuromuscular junction
regulation of actin nucleation (GO:0051125)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
negative regulation of actin nucleation (GO:0051126)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms: down regulation of actin nucleation; down-regulation of actin nucleation; downregulation of actin nucleation; inhibition of actin nucleation
positive regulation of actin nucleation (GO:0051127)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms: activation of actin nucleation; stimulation of actin nucleation; up regulation of actin nucleation; up-regulation of actin nucleation; upregulation of actin nucleation
regulation of cellular component organization (GO:0051128)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
Synonyms: regulation of cell organisation; regulation of cell organization; regulation of cellular component organisation; regulation of cellular component organization and biogenesis
negative regulation of cellular component organization (GO:0051129)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
Synonyms: down regulation of cell organization; down-regulation of cell organization; downregulation of cell organization; inhibition of cell organization; negative regulation of cell organisation; negative regulation of cellular component organization and biogenesis
positive regulation of cellular component organization (GO:0051130)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
Synonyms: activation of cell organization; positive regulation of cell organisation; positive regulation of cellular component organization and biogenesis; stimulation of cell organization; up regulation of cell organization; up-regulation of cell organization; upregulation of cell organization
chaperone-mediated protein complex assembly (GO:0051131)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
Synonyms: cellular chaperone-mediated protein complex assembly; chaperone activity; protein complex assembly, multichaperone pathway
NK T cell activation (GO:0051132)
Namespace: biological_process
Definition: The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms: natural killer T cell activation; natural T cell activation; NK T lymphocyte activation; NK T-cell activation; NK T-lymphocyte activation; NKT cell activation; NT cell activation
Comment: Note that NK T cells are a distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments.
regulation of NK T cell activation (GO:0051133)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of natural killer T cell activation.
Synonyms: regulation of natural killer T cell activation; regulation of natural T cell activation; regulation of NK T lymphocyte activation; regulation of NK T-cell activation; regulation of NK T-lymphocyte activation; regulation of NKT cell activation; regulation of NT cell activation
negative regulation of NK T cell activation (GO:0051134)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.
Synonyms: down regulation of NK T cell activation; down-regulation of NK T cell activation; downregulation of NK T cell activation; inhibition of NK T cell activation; negative regulation of natural killer T cell activation; negative regulation of natural T cell activation; negative regulation of NK T lymphocyte activation; negative regulation of NK T-cell activation; negative regulation of NK T-lymphocyte activation; negative regulation of NKT cell activation; negative regulation of NT cell activation
regulation of NK T cell differentiation (GO:0051136)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.
Synonyms: regulation of natural killer T cell differentiation; regulation of natural T cell differentiation; regulation of NK T cell development; regulation of NK T lymphocyte differentiation; regulation of NK T-cell differentiation; regulation of NK T-lymphocyte differentiation; regulation of NKT cell differentiation; regulation of NT cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
negative regulation of NK T cell differentiation (GO:0051137)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.
Synonyms: down regulation of NK T cell differentiation; down-regulation of NK T cell differentiation; downregulation of NK T cell differentiation; inhibition of NK T cell differentiation; negative regulation of natural killer T cell differentiation; negative regulation of natural T cell differentiation; negative regulation of NK T cell development; negative regulation of NK T lymphocyte differentiation; negative regulation of NK T-cell differentiation; negative regulation of NK T-lymphocyte differentiation; negative regulation of NKT cell differentiation; negative regulation of NT cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
positive regulation of NK T cell differentiation (GO:0051138)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.
Synonyms: activation of NK T cell differentiation; positive regulation of natural killer T cell differentiation; positive regulation of natural T cell differentiation; positive regulation of NK T cell development; positive regulation of NK T lymphocyte differentiation; positive regulation of NK T-cell differentiation; positive regulation of NK T-lymphocyte differentiation; positive regulation of NKT cell differentiation; positive regulation of NT cell differentiation; stimulation of NK T cell differentiation; up regulation of NK T cell differentiation; up-regulation of NK T cell differentiation; upregulation of NK T cell differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
metal cation:proton antiporter activity (GO:0051139)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).
Synonyms: metal ion:hydrogen antiporter activity; metal ion:proton antiporter activity
regulation of NK T cell proliferation (GO:0051140)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.
Synonyms: regulation of natural killer T cell proliferation; regulation of natural T cell proliferation; regulation of NK T lymphocyte proliferation; regulation of NK T-cell proliferation; regulation of NK T-lymphocyte proliferation; regulation of NKT cell proliferation; regulation of NT cell proliferation
positive regulation of NK T cell proliferation (GO:0051142)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.
Synonyms: activation of NK T cell proliferation; positive regulation of natural killer T cell proliferation; positive regulation of natural T cell proliferation; positive regulation of NK T lymphocyte proliferation; positive regulation of NK T-cell proliferation; positive regulation of NK T-lymphocyte proliferation; positive regulation of NKT cell proliferation; positive regulation of NT cell proliferation; stimulation of NK T cell proliferation; up regulation of NK T cell proliferation; up-regulation of NK T cell proliferation; upregulation of NK T cell proliferation
obsolete propanediol metabolic process (GO:0051143)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.
Synonyms: 1,2-dihydroxypropane metabolic process; 1,2-dihydroxypropane metabolism; propanediol metabolism; propylene glycol metabolic process; propylene glycol metabolism
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
smooth muscle cell differentiation (GO:0051145)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
Synonyms: nonstriated muscle cell differentiation
striated muscle cell differentiation (GO:0051146)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
Synonyms: voluntary muscle cell differentiation
regulation of muscle cell differentiation (GO:0051147)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of muscle cell differentiation.
negative regulation of muscle cell differentiation (GO:0051148)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.
Synonyms: down regulation of muscle cell differentiation; down-regulation of muscle cell differentiation; downregulation of muscle cell differentiation; inhibition of muscle cell differentiation
positive regulation of muscle cell differentiation (GO:0051149)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.
Synonyms: activation of muscle cell differentiation; stimulation of muscle cell differentiation; up regulation of muscle cell differentiation; up-regulation of muscle cell differentiation; upregulation of muscle cell differentiation
regulation of smooth muscle cell differentiation (GO:0051150)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.
positive regulation of smooth muscle cell differentiation (GO:0051152)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.
Synonyms: activation of smooth muscle cell differentiation; stimulation of smooth muscle cell differentiation; up regulation of smooth muscle cell differentiation; up-regulation of smooth muscle cell differentiation; upregulation of smooth muscle cell differentiation
regulation of striated muscle cell differentiation (GO:0051153)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.
negative regulation of striated muscle cell differentiation (GO:0051154)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
Synonyms: down regulation of striated muscle cell differentiation; down-regulation of striated muscle cell differentiation; downregulation of striated muscle cell differentiation; inhibition of striated muscle cell differentiation
arabitol catabolic process (GO:0051157)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
Synonyms: arabitol breakdown; arabitol catabolism; arabitol degradation; arabitol utilization
L-arabitol catabolic process (GO:0051158)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
Synonyms: L-arabitol breakdown; L-arabitol catabolism; L-arabitol degradation
D-arabitol catabolic process (GO:0051159)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
Synonyms: D-arabitol breakdown; D-arabitol catabolism; D-arabitol degradation
xylitol catabolic process (GO:0051160)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.
Synonyms: L-xylitol breakdown; L-xylitol catabolism; L-xylitol degradation
Comment: Note that xylitol is a meso compound, thus there are no L or D-versions.
obsolete L-arabitol metabolic process (GO:0051162)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
Synonyms: L-arabitol metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.