LiteFold/GO huggingface dataset:
TSC1-TSC2 complex (GO:0033596)
Namespace: cellular_component
Definition: A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.
Synonyms: tuberin-hamartin complex; tuberous sclerosis complex
mitotic checkpoint complex (GO:0033597)
Namespace: cellular_component
Definition: A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.
Synonyms: MCC
regulation of mammary gland epithelial cell proliferation (GO:0033599)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.
negative regulation of mammary gland epithelial cell proliferation (GO:0033600)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.
Synonyms: down regulation of mammary gland epithelial cell proliferation; down-regulation of mammary gland epithelial cell proliferation; downregulation of mammary gland epithelial cell proliferation; inhibition of mammary gland epithelial cell proliferation
positive regulation of mammary gland epithelial cell proliferation (GO:0033601)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.
Synonyms: activation of mammary gland epithelial cell proliferation; stimulation of mammary gland epithelial cell proliferation; up regulation of mammary gland epithelial cell proliferation; up-regulation of mammary gland epithelial cell proliferation; upregulation of mammary gland epithelial cell proliferation
negative regulation of dopamine secretion (GO:0033602)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.
Synonyms: down regulation of dopamine secretion; down-regulation of dopamine secretion; downregulation of dopamine secretion; inhibition of dopamine secretion
positive regulation of dopamine secretion (GO:0033603)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
Synonyms: activation of dopamine secretion; stimulation of dopamine secretion; up regulation of dopamine secretion; up-regulation of dopamine secretion; upregulation of dopamine secretion
negative regulation of catecholamine secretion (GO:0033604)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.
Synonyms: down regulation of catecholamine secretion; down-regulation of catecholamine secretion; downregulation of catecholamine secretion; inhibition of catecholamine secretion
positive regulation of catecholamine secretion (GO:0033605)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.
Synonyms: activation of catecholamine secretion; stimulation of catecholamine secretion; up regulation of catecholamine secretion; up-regulation of catecholamine secretion; upregulation of catecholamine secretion
chemokine receptor transport within lipid bilayer (GO:0033606)
Namespace: biological_process
Definition: The directed movement of a chemokine receptor within a lipid bilayer.
Synonyms: chemokine receptor translocation within membrane
SOD1-Bcl-2 complex (GO:0033607)
Namespace: cellular_component
Definition: A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.
formyl-CoA transferase activity (GO:0033608)
Namespace: molecular_function
Definition: Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.
Synonyms: formyl-CoA oxalate CoA-transferase activity; formyl-CoA:oxalate CoA-transferase activity; formyl-coenzyme A transferase activity
oxalate metabolic process (GO:0033609)
Namespace: biological_process
Definition: The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
Synonyms: ethanedioate metabolic process; ethanedioic acid metabolic process; oxalate metabolism; oxalic acid metabolic process
oxalate biosynthetic process (GO:0033610)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.
Synonyms: ethanedioate biosynthetic process; ethanedioic acid biosynthetic process; oxalate anabolism; oxalate biosynthesis; oxalate formation; oxalate synthesis; oxalic acid biosynthetic process
receptor serine/threonine kinase binding (GO:0033612)
Namespace: molecular_function
Definition: Binding to a receptor that possesses protein serine/threonine kinase activity.
Synonyms: transmembrane receptor protein serine/threonine kinase ligand binding
chloroplast proton-transporting ATP synthase complex assembly (GO:0033614)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.
mitochondrial proton-transporting ATP synthase complex assembly (GO:0033615)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
plasma membrane proton-transporting ATP synthase complex assembly (GO:0033616)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.
mitochondrial respiratory chain complex IV assembly (GO:0033617)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
Synonyms: mitochondrial cytochrome c oxidase assembly; mitochondrial cytochrome c oxidase biogenesis; mitochondrial cytochrome c oxidase complex assembly
plasma membrane respiratory chain complex IV assembly (GO:0033618)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.
Synonyms: plasma membrane cytochrome c oxidase biogenesis; plasma membrane cytochrome c oxidase complex assembly
membrane protein proteolysis (GO:0033619)
Namespace: biological_process
Definition: The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
Mei2 nuclear dot complex (GO:0033620)
Namespace: cellular_component
Definition: A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.
Synonyms: Mei2 dot; Mei2 nuclear dot; nuclear body
nuclear mRNA surveillance of meiosis-specific transcripts (GO:0033621)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
Synonyms: degradation of meiosis-specific transcripts; mRNA breakdown, meiosis-specific transcripts; mRNA catabolism, meiosis-specific transcripts; mRNA degradation, meiosis-specific transcripts; nuclear mRNA catabolic process, meiosis-specific transcripts; nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts
Comment: Note that it is speculated that higher eukaryotic YTH-family protein may be involved in similar mechanisms to suppress gene regulation during gametogenesis or general silencing.
integrin activation (GO:0033622)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
Synonyms: integrin complex activation; integrin complex assembly
regulation of integrin activation (GO:0033623)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of integrin activation.
Synonyms: regulation of integrin complex activation
positive regulation of integrin activation (GO:0033625)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of integrin activation.
Synonyms: positive regulation of integrin complex activation
positive regulation of integrin activation by cell surface receptor linked signal transduction (GO:0033626)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of integrin activation by cell surface receptor linked signal transduction. This can occur by increased affinity of an integrin for its extracellular ligands.
Synonyms: cell surface receptor linked signal transduction leading to integrin activation; cell surface receptor linked signal transduction leading to integrin complex activation
cell adhesion mediated by integrin (GO:0033627)
Namespace: biological_process
Definition: The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
Synonyms: cell adhesion mediated by integrin complex
regulation of cell adhesion mediated by integrin (GO:0033628)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
Synonyms: regulation of cell adhesion mediated by integrin complex
negative regulation of cell adhesion mediated by integrin (GO:0033629)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.
Synonyms: negative regulation of cell adhesion mediated by integrin complex
positive regulation of cell adhesion mediated by integrin (GO:0033630)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
Synonyms: positive regulation of cell adhesion mediated by integrin complex
cell-cell adhesion mediated by integrin (GO:0033631)
Namespace: biological_process
Definition: The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
Synonyms: cell-cell adhesion mediated by integrin complex
regulation of cell-cell adhesion mediated by integrin (GO:0033632)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
Synonyms: regulation of cell-cell adhesion mediated by integrin complex
negative regulation of cell-cell adhesion mediated by integrin (GO:0033633)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
Synonyms: negative regulation of cell-cell adhesion mediated by integrin complex
positive regulation of cell-cell adhesion mediated by integrin (GO:0033634)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
Synonyms: positive regulation of cell-cell adhesion mediated by integrin complex
symbiont-mediated perturbation of host response to abiotic stimulus (GO:0033635)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts the response of its host to an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modulation by symbiont of host response to abiotic stimulus
obsolete modulation by symbiont of host response to temperature stimulus (GO:0033636)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modulation by symbiont of host response to thermal stimulus
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete modulation by symbiont of host response to cold (GO:0033637)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: freezing tolerance
Comment: This term was obsoleted because there is no evidence that this process exists.
symbiont-mediated perturbation of host heat acclimation (GO:0033638)
Namespace: biological_process
Definition: A process in which a symbiont alters or subverts the response of its host to heat acclimation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modulation by symbiont of host heat acclimation; modulation by symbiont of host response to heat; response to heat shock
obsolete modulation by symbiont of host response to water (GO:0033639)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete modulation by symbiont of host response to pH (GO:0033641)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because there is no evidence that this process exists.
host cell part (GO:0033643)
Namespace: cellular_component
Definition: Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
host cell membrane (GO:0033644)
Namespace: cellular_component
Definition: Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell endomembrane system (GO:0033645)
Namespace: cellular_component
Definition: A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host intracellular part (GO:0033646)
Namespace: cellular_component
Definition: Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: host cell intracellular part
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
host intracellular organelle (GO:0033647)
Namespace: cellular_component
Definition: Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host intracellular membrane-bounded organelle (GO:0033648)
Namespace: cellular_component
Definition: Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: host intracellular membrane-enclosed organelle
host cell mitochondrion (GO:0033650)
Namespace: cellular_component
Definition: A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: host mitochondria
host cell plastid (GO:0033651)
Namespace: cellular_component
Definition: Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell chloroplast (GO:0033652)
Namespace: cellular_component
Definition: A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell chloroplast part (GO:0033653)
Namespace: cellular_component
Definition: Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: host chloroplast component
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
host cell chloroplast thylakoid membrane (GO:0033654)
Namespace: cellular_component
Definition: Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell cytoplasm part (GO:0033655)
Namespace: cellular_component
Definition: Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: cytoplasm component
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
symbiont-mediated disruption of host chloroplast (GO:0033656)
Namespace: biological_process
Definition: The process in which an organism effects a change that impairs the structure or function of the host chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: disruption by symbiont of host chloroplast; modification by symbiont of host chloroplast
obsolete disruption by symbiont of host chloroplast part (GO:0033657)
Namespace: biological_process
Definition: OBSOLETE. The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modification by symbiont of host chloroplast part
Comment: This term was obsoleted because it was an unnecessary grouping class.
symbiont-mediated disruption of host chloroplast thylakoid (GO:0033658)
Namespace: biological_process
Definition: The process in which an organism effects a change that impairs the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: disruption by symbiont of host chloroplast thylakoid; modification by symbiont of host chloroplast thylakoid
symbiont-mediated disruption of host mitochondrion (GO:0033659)
Namespace: biological_process
Definition: The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: disruption by symbiont of host mitochondrion; modification by symbiont of host mitochondrion
symbiont-mediated suppression of host resistance gene-dependent defense response (GO:0033660)
Namespace: biological_process
Definition: A process in which a symbiont inhibits or disrupts the normal execution of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: down regulation by symbiont of defense response in host by specific elicitors; down-regulation by symbiont of host gene-for-gene resistance; downregulation by symbiont of pathogen-race/host plant cultivar-specific resistance in symbiont; inhibition by symbiont of host resistance gene-dependent defense response; negative regulation by symbiont of host resistance gene-dependent defense response; suppression by symbiont of host resistance gene-dependent defense response