LiteFold/GO huggingface dataset:
orotidine-5'-phosphate decarboxylase activity (GO:0004590)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + orotidine 5'-phosphate = CO2 + UMP.
Synonyms: ODCase activity; OMP decarboxylase activity; OMP-DC; OMPdcase activity; orotate decarboxylase activity; orotate monophosphate decarboxylase activity; orotic decarboxylase activity; orotidine 5'-phosphate decarboxylase activity; orotidine monophosphate decarboxylase activity; orotidine phosphate decarboxylase activity; orotidine-5'-monophosphate decarboxylase activity; orotidine-5'-phosphate carboxy-lyase (UMP-forming); orotidine-5'-phosphate carboxy-lyase activity; orotidylic acid decarboxylase activity; orotidylic decarboxylase activity; orotodylate decarboxylase activity; UMP synthase activity; uridine 5'-monophosphate synthase activity
oxoglutarate dehydrogenase (succinyl-transferring) activity (GO:0004591)
Namespace: molecular_function
Definition: Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H+ = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2.
Synonyms: 2-ketoglutarate dehydrogenase activity; 2-oxoglutarate dehydrogenase activity; 2-oxoglutarate: lipoate oxidoreductase activity; 2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating); 2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity; AKGDH activity; alpha-ketoglutarate dehydrogenase activity; alpha-ketoglutaric acid dehydrogenase activity; alpha-ketoglutaric dehydrogenase activity; alpha-oxoglutarate dehydrogenase activity; ketoglutaric dehydrogenase activity; OGDC activity; oxoglutarate decarboxylase activity; oxoglutarate dehydrogenase (lipoamide) activity; oxoglutarate dehydrogenase activity
pantoate-beta-alanine ligase activity (GO:0004592)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
Synonyms: (R)-pantoate:beta-alanine ligase (AMP-forming); D-pantoate:beta-alanine ligase (AMP-forming); pantoate-activating enzyme activity; pantoic-activating enzyme activity; pantothenate synthetase activity
pantothenase activity (GO:0004593)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-pantothenate + H2O = (R)-pantoate + beta-alanine.
Synonyms: (R)-pantothenate amidohydrolase activity; pantothenate amidohydrolase activity; pantothenate hydrolase activity
pantetheine-phosphate adenylyltransferase activity (GO:0004595)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.
Synonyms: 3'-dephospho-CoA pyrophosphorylase activity; ATP:pantetheine-4'-phosphate adenylyltransferase activity; ATP:pantetheine-phosphate adenylyltransferase activity; dephospho-CoA diphosphorylase activity; dephospho-CoA pyrophosphorylase activity; dephospho-coenzyme A pyrophosphorylase activity; pantetheine phosphate adenylyltransferase activity; phosphopantetheine adenylyltransferase activity; PPAT activity
protein-N-terminal amino-acid acetyltransferase activity (GO:0004596)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] = CoA + H+ + N-terminal Nalpha-acetyl-L-alpha-aminoacyl-[protein].
Synonyms: acetyl-CoA:peptide alpha-N-acetyltransferase activity; acetyl-CoA:peptide nalpha-acetyltransferase activity; amino-terminal amino acid-acetylating enzyme activity; beta-endorphin acetyltransferase activity; N(alpha)-acetyltransferase activity; nalpha-acetyltransferase activity; NAT activity; peptide acetyltransferase activity; peptide alpha-N-acetyltransferase activity; protein N-terminal acetyltransferase activity
peptidylamidoglycolate lyase activity (GO:0004598)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.
Synonyms: alpha-hydroxyglycine amidating dealkylase activity; HGAD; PAL; peptidyl-alpha-hydroxyglycine alpha-amidating lyase activity; peptidylamidoglycolate peptidylamide-lyase (glyoxylate-forming); peptidylamidoglycolate peptidylamide-lyase activity; PGL
obsolete cyclophilin (GO:0004600)
Namespace: molecular_function
Definition: OBSOLETE. A protein to which cyclosporin A (an immunosuppressant) binds. Possesses peptidyl-prolyl isomerase activity.
Synonyms: cyclophilin
Comment: This term was made obsolete because it does not represent a molecular function.
peroxidase activity (GO:0004601)
Namespace: molecular_function
Definition: Catalysis of the reaction: a reduced substrate + ROOH = an oxidized substrate + ROH + H2O.
Synonyms: bacterial catalase-peroxidase activity; donor:hydrogen-peroxide oxidoreductase activity; eosinophil peroxidase activity; extensin peroxidase; guaiacol peroxidase; heme peroxidase; horseradish peroxidase (HRP); japanese radish peroxidase; lactoperoxidase activity; MPO; myeloperoxidase activity; oxyperoxidase activity; peroxidase reaction; protoheme peroxidase; pyrocatechol peroxidase; scopoletin peroxidase; secretory plant peroxidase activity; thiocyanate peroxidase; verdoperoxidase
glutathione peroxidase activity (GO:0004602)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 glutathione + H2O2 = oxidized glutathione + 2 H2O.
Synonyms: glutathione:hydrogen-peroxide oxidoreductase activity; GSH peroxidase activity; non-selenium glutathione peroxidase activity; reduced glutathione peroxidase activity; selenium-glutathione peroxidase activity
phenylethanolamine N-methyltransferase activity (GO:0004603)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.
Synonyms: noradrenalin N-methyltransferase activity; noradrenaline N-methyltransferase activity; norepinephrine methyltransferase activity; norepinephrine N-methyltransferase activity; phenethanolamine methyltransferase activity; phenethanolamine N-methyltransferase activity; S-adenosyl-L-methionine:phenylethanolamine N-methyltransferase activity
phosphoadenylyl-sulfate reductase (thioredoxin) activity (GO:0004604)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosine 3',5'-diphosphate + H+ + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
Synonyms: 3'-phosphoadenylylsulfate reductase activity; adenosine 3',5'-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming); adenosine 3',5'-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3'-phosphoadenosine-5'-phosphosulfate-forming); PAdoPS reductase activity; PAPS reductase activity; PAPS reductase, thioredoxin-dependent activity; PAPS sulfotransferase activity; phosphoadenosine-phosphosulfate reductase activity; phosphoadenylyl-sulphate reductase (thioredoxin) activity; thioredoxin:3'-phospho-adenylylsulfate reductase activity; thioredoxin:adenosine 3'-phosphate 5'-phosphosulfate reductase activity
phosphatidate cytidylyltransferase activity (GO:0004605)
Namespace: molecular_function
Definition: Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
Synonyms: CDP diglyceride pyrophosphorylase activity; CDP-DG; CDP-diacylglyceride synthetase activity; CDP-diacylglycerol synthase activity; CDP-diglyceride diphosphorylase activity; CDP-diglyceride pyrophosphorylase activity; CDP-diglyceride synthase activity; CDP-diglyceride synthetase activity; CTP-diacylglycerol synthetase activity; CTP:1,2-diacylglycerophosphate-cytidyl transferase activity; CTP:phosphatidate cytidylyltransferase activity; cytidine diphosphoglyceride pyrophosphorylase activity; DAG synthetase activity; phosphatidate cytidyltransferase activity; phosphatidic acid cytidylyltransferase activity
phosphatidylcholine-sterol O-acyltransferase activity (GO:0004607)
Namespace: molecular_function
Definition: Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.
Synonyms: LCAT (lecithin-cholesterol acyltransferase); LCAT activity; lecithin--cholesterol acyltransferase activity; lecithin:cholesterol acyltransferase activity; phosphatidylcholine:sterol O-acyltransferase activity; phospholipid--cholesterol acyltransferase activity
phosphatidylethanolamine N-methyltransferase activity (GO:0004608)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.
Synonyms: lipid methyl transferase activity; LMTase activity; PEMT; phosphatidylethanolamine methyltransferase activity; phosphatidylethanolamine-N-methylase activity; phosphatidylethanolamine-S-adenosylmethionine methyltransferase activity; S-adenosyl-L-methionine:phosphatidylethanolamine N-methyltransferase activity
phosphatidylserine decarboxylase activity (GO:0004609)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + phosphatidyl-L-serine = CO2 + phosphatidylethanolamine.
Synonyms: phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming); phosphatidyl-L-serine carboxy-lyase activity; PS decarboxylase activity
phosphoacetylglucosamine mutase activity (GO:0004610)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.
Synonyms: acetylaminodeoxyglucose phosphomutase activity; acetylglucosamine phosphomutase activity; N-acetyl-alpha-D-glucosamine 1,6-phosphomutase activity; N-acetyl-D-glucosamine 1,6-phosphomutase activity; N-acetylglucosamine-phosphate mutase activity; phospho-N-acetylglucosamine mutase activity
phosphoenolpyruvate carboxykinase activity (GO:0004611)
Namespace: molecular_function
Definition: Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.
Synonyms: PEP carboxykinase activity; PEPCK activity; phosphopyruvate carboxylase activity
phosphoenolpyruvate carboxykinase (ATP) activity (GO:0004612)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + oxaloacetate = ADP + CO2 + H+ + phosphoenolpyruvate.
Synonyms: ATP:oxaloacetate carboxy-lyase (transphosphorylating); ATP:oxaloacetate carboxy-lyase (transphosphorylating; phosphoenolpyruvate-forming); PEPCK (ATP); PEPK; phosphoenolpyruvate carboxylase (ATP); phosphoenolpyruvic carboxykinase; phosphopyruvate carboxykinase; phosphopyruvate carboxykinase (adenosine triphosphate); phosphopyruvate carboxylase (ATP)
phosphoenolpyruvate carboxykinase (GTP) activity (GO:0004613)
Namespace: molecular_function
Definition: Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.
Synonyms: GTP:oxaloacetate carboxy-lyase (adding GTP; phosphoenolpyruvate-forming); GTP:oxaloacetate carboxy-lyase (transphosphorylating); phosphoenolpyruvate carboxylase (GTP); phosphoenolpyruvic carboxykinase; phosphoenolpyruvic carboxykinase (GTP); phosphoenolpyruvic carboxylase (GTP); phosphopyruvate (guanosine triphosphate) carboxykinase activity; phosphopyruvate carboxylase (GTP)
phosphoglucomutase activity (GO:0004614)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Synonyms: alpha-D-glucose 1,6-phosphomutase activity; glucose phosphomutase activity; phosphoglucose mutase activity
phosphomannomutase activity (GO:0004615)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
Synonyms: alpha-D-mannose 1,6-phosphomutase activity; D-mannose 1,6-phosphomutase activity; mannose phosphomutase activity; phosphomannose mutase activity
phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616)
Namespace: molecular_function
Definition: Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
Synonyms: 6-phospho-D-gluconate dehydrogenase activity; 6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating); 6-phosphogluconate dehydrogenase (decarboxylating); 6-phosphogluconic carboxylase activity; 6-phosphogluconic dehydrogenase activity; 6PGD activity; phosphogluconic acid dehydrogenase activity
phosphoglycerate dehydrogenase activity (GO:0004617)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.
Synonyms: 3-phospho-D-glycerate:NAD+ 2-oxidoreductase activity; 3-phosphoglycerate dehydrogenase activity; 3-phosphoglycerate:NAD+ 2-oxidoreductase activity; 3-phosphoglyceric acid dehydrogenase activity; 3PHP reductase activity; alpha-KG reductase activity; alpha-phosphoglycerate dehydrogenase activity; alphaKG reductase activity; D- and L-HGA; D-3-phosphoglycerate dehydrogenase activity; D-3-phosphoglycerate:NAD+ oxidoreductase activity; glycerate 3-phosphate dehydrogenase activity; glycerate-1,3-phosphate dehydrogenase activity; PGDH activity; phosphoglycerate oxidoreductase activity; phosphoglyceric acid dehydrogenase activity; SerA; SerA 3PG dehydrogenase activity
phosphoglycerate kinase activity (GO:0004618)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H+.
Synonyms: 3-PGK; 3-phosphoglycerate kinase activity; 3-phosphoglycerate phosphokinase activity; 3-phosphoglyceric acid kinase activity; 3-phosphoglyceric acid phosphokinase activity; 3-phosphoglyceric kinase activity; ATP-3-phospho-D-glycerate-1-phosphotransferase activity; ATP:3-phospho-D-glycerate 1-phosphotransferase activity; ATP:D-3-phosphoglycerate 1-phosphotransferase activity; glycerate 3-phosphate kinase activity; glycerophosphate kinase activity; PGK; phosphoglyceric acid kinase activity; phosphoglyceric kinase activity; phosphoglycerokinase activity
phosphoglycerate mutase activity (GO:0004619)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate.
Synonyms: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity; D-phosphoglycerate 2,3-phosphomutase activity; PGA mutase activity; PGAM activity; PGM; phosphoglycerate phosphomutase activity; phosphoglyceromutase activity
glycerophospholipase activity (GO:0004620)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a glycerophospholipid.
Synonyms: glycerophospholipid hydrolase activity; phospholipase activity
GPI anchor phospholipase D activity (GO:0004621)
Namespace: molecular_function
Definition: Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol, by cleavage of the second phosphodiester bond between the phosphate and phospholipid.
Synonyms: glycoprotein phospholipase D activity; glycoprotein-phosphatidylinositol phosphatidohydrolase activity; glycosylphosphatidyl inositol-anchor protein phospholipase D activity; GPI-PLD activity
phosphatidylcholine lysophospholipase A1 activity (GO:0004622)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholine.
Synonyms: 2-lysophosphatidylcholine acylhydrolase activity; lecithinase B activity; lecitholipase activity; lysolecithinase activity; lysophopholipase L2; lysophosphatidase activity; lysophosphatidylcholine hydrolase activity; lysophospholipase A1; lysophospholipase activity; phosphatidase B; phosphatidylcholine lysophospholipase A1-type activity; phospholipase B activity
A2-type glycerophospholipase activity (GO:0004623)
Namespace: molecular_function
Definition: A glycerophospholipase activity that cleaves the fatty acid attached to the sn-2 position of the glycerol group of a glycerophospholipid. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.
Synonyms: cytosolic phospholipase A2 activity; lecithinase A activity; phosphatidase activity; phosphatidolipase activity; phosphatidylcholine 2-acylhydrolase activity; phospholipase A2 activity; phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine); phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine); secreted phospholipase A2 activity
obsolete secreted phospholipase A2 activity (GO:0004624)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.
Synonyms: secreted phospholipase A2 activity
Comment: This term was made obsolete because it represents component and function information.
obsolete calcium-dependent secreted phospholipase A2 activity (GO:0004625)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.
Synonyms: calcium-dependent secreted phospholipase A2 activity
Comment: This term was made obsolete because it represents component and function information.
obsolete cytosolic phospholipase A2 activity (GO:0004626)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.
Synonyms: cytosolic phospholipase A2 activity
Comment: This term was made obsolete because it represents component and function information.
obsolete calcium-independent cytosolic phospholipase A2 activity (GO:0004628)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a fatty acid anion.
Synonyms: calcium-independent cytosolic phospholipase A2 activity
Comment: This term was made obsolete because it represents component and function information.
C-type glycerophospholipase activity (GO:0004629)
Namespace: molecular_function
Definition: A glycerophospholipase activity that cleaves the first phosphodiester bond between the phosphate and glycerol, producing a mono- or a diacylglycerol, depending on whether the substrate is a lysoglycerophospholipid or a glycerophospholipid.
Synonyms: C-type phospholipase activity; phosphatidase C; phospholipase C activity
D-type glycerophospholipase activity (GO:0004630)
Namespace: molecular_function
Definition: A glycerophospholipase activity that cleaves the second phosphodiester bond between the phosphate and phospholipid, releasing a phosphatidic acid.
Synonyms: choline phosphatase activity; D-type phospholipase activity; lecithinase D activity; lipophosphodiesterase II activity; phosphatidylcholine phosphatidohydrolase activity; phospholipase D activity
phosphomevalonate kinase activity (GO:0004631)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H+.
Synonyms: 5-phosphomevalonate kinase activity; ATP:(R)-5-phosphomevalonate phosphotransferase activity; ATP:5-phosphomevalonate phosphotransferase activity; mevalonate phosphate kinase activity; mevalonate-5-phosphate kinase activity; mevalonic acid phosphate kinase activity
phosphopantothenoylcysteine decarboxylase activity (GO:0004633)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H+ = CO2 + pantetheine 4'-phosphate.
Synonyms: 4-phosphopantothenoyl-L-cysteine decarboxylase activity; 4-phosphopantotheoylcysteine decarboxylase activity; N-((R)-4'-phosphopantothenoyl)-L-cysteine carboxy-lyase activity; N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase (pantotheine-4'-phosphate-forming); N-[(R)-4'-phosphopantothenoyl]-L-cysteine carboxy-lyase activity; PPC-decarboxylase activity
phosphopyruvate hydratase activity (GO:0004634)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
Synonyms: 14-3-2-protein; 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming); 2-phospho-D-glycerate hydro-lyase activity; 2-phospho-D-glycerate-hydrolase activity; 2-phosphoglycerate dehydratase activity; 2-phosphoglycerate enolase activity; 2-phosphoglyceric dehydratase activity; enolase activity; gamma-enolase activity; nervous-system specific enolase; phosphoenolpyruvate hydratase activity
phosphoribosyl-AMP cyclohydrolase activity (GO:0004635)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H2O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.
Synonyms: 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity; phosphoribosyladenosine monophosphate cyclohydrolase activity; PRAMP-cyclohydrolase activity
phosphoribosylamine-glycine ligase activity (GO:0004637)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.
Synonyms: 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase activity; 5'-phosphoribosylglycinamide synthetase activity; 5-phospho-D-ribosylamine:glycine ligase (ADP-forming); GAR; GAR synthetase activity; GARS activity; glycinamide ribonucleotide synthetase activity; glycineamide ribonucleotide synthetase activity; phosphoribosylglycinamide synthetase activity; phosphoribosylglycineamide synthetase activity
phosphoribosylaminoimidazole carboxylase activity (GO:0004638)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H+ = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2.
Synonyms: 1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase activity; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase [5-amino-1-(5-phospho-D-ribosyl)imidazole-forming]; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase activity; 5-amino-1-ribosylimidazole 5-phosphate carboxylase activity; 5-phosphoribosyl-5-aminoimidazole carboxylase activity; ADE2; AIR carboxylase activity; class II PurE
phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (GO:0004639)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H+ + phosphate.
Synonyms: 4-((N-succinylamino)carbonyl)-5-aminoimidazole ribonucleotide synthetase activity; 4-(N-succinocarboxamide)-5-aminoimidazole synthetase activity; 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase activity; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate:L-aspartate ligase (ADP-forming); 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase activity; phosphoribosylaminoimidazole-succinocarboxamide synthase activity; phosphoribosylaminoimidazole-succinocarboxamide synthetase activity; phosphoribosylaminoimidazolesuccinocarboxamide synthetase activity; PurC; SAICAR synthase activity; SAICAR synthetase activity; SAICARs activity
phosphoribosylanthranilate isomerase activity (GO:0004640)
Namespace: molecular_function
Definition: Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
Synonyms: IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex); N-(5'-phosphoribosyl)anthranilate isomerase activity; N-(5-phospho-beta-D-ribosyl)anthranilate aldose-ketose-isomerase activity; N-(5-phospho-beta-D-ribosyl)anthranilate ketol-isomerase activity; PRA isomerase activity; PRAI activity