LiteFold/GO huggingface dataset:
obsolete juvenile hormone acid methyltransferase activity (GO:0035049)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a methyl group to juvenile hormone acid.
Comment: This term was obsoleted because it represents the same activity as farnesoic acid O-methyltransferase activity ; GO:0019010.
embryonic heart tube development (GO:0035050)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
dorsal vessel aortic cell fate commitment (GO:0035052)
Namespace: biological_process
Definition: The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.
dorsal vessel heart proper cell fate commitment (GO:0035053)
Namespace: biological_process
Definition: The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.
embryonic heart tube anterior/posterior pattern specification (GO:0035054)
Namespace: biological_process
Definition: The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
RCAF complex (GO:0035059)
Namespace: cellular_component
Definition: A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.
Synonyms: replication-coupling assembly factor complex
brahma complex (GO:0035060)
Namespace: cellular_component
Definition: A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the Drosophila brm (brahma) or mammalian SMARCA2/BAF190B/BRM gene, or an ortholog thereof.
Synonyms: BRM complex
interchromatin granule (GO:0035061)
Namespace: cellular_component
Definition: A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
Synonyms: ICG
omega speckle (GO:0035062)
Namespace: cellular_component
Definition: A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).
nuclear speck organization (GO:0035063)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.
Synonyms: nuclear speck organisation; nuclear speck organization and biogenesis; nuclear speckle assembly; nuclear speckle organization
Comment: See also the cellular component term 'nuclear speck ; GO:0016607'.
obsolete methylated histone binding (GO:0035064)
Namespace: molecular_function
Definition: OBSOLETE. Binding to a histone in which a residue has been modified by methylation.
Comment: This term was obsoleted because it should be captured as histone reader activity ; GO:0140566 or a child.
obsolete regulation of histone acetylation (GO:0035065)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of histone acetylation (GO:0035066)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
Synonyms: activation of histone acetylation; stimulation of histone acetylation; up regulation of histone acetylation; up-regulation of histone acetylation; upregulation of histone acetylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of histone acetylation (GO:0035067)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.
Synonyms: down regulation of histone acetylation; down-regulation of histone acetylation; downregulation of histone acetylation; inhibition of histone acetylation
Comment: This term was obsoleted because it represents a molecular function.
larval midgut histolysis (GO:0035069)
Namespace: biological_process
Definition: The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
Synonyms: larval midgut regression
salivary gland histolysis (GO:0035070)
Namespace: biological_process
Definition: The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
Synonyms: salivary gland regression
obsolete salivary gland cell autophagic cell death (GO:0035071)
Namespace: biological_process
Definition: OBSOLETE. The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
Comment: The reason for obsoletion is that this term was added in error.
pupariation (GO:0035073)
Namespace: biological_process
Definition: The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.
Synonyms: puparium biosynthesis; puparium formation
pupation (GO:0035074)
Namespace: biological_process
Definition: The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.
Synonyms: head eversion; prepupal-pupal transition
response to ecdysone (GO:0035075)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
ecdysone receptor signaling pathway (GO:0035076)
Namespace: biological_process
Definition: A nuclear receptor-mediated signaling pathway initiated by an ecdysone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms: ecdysone receptor-mediated signalling pathway; nuclear receptor-mediated ecdysone signaling pathway
ecdysone-mediated polytene chromosome puffing (GO:0035077)
Namespace: biological_process
Definition: The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.
polytene chromosome puffing (GO:0035079)
Namespace: biological_process
Definition: The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.
heat shock-mediated polytene chromosome puffing (GO:0035080)
Namespace: biological_process
Definition: The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.
induction of programmed cell death by hormones (GO:0035081)
Namespace: biological_process
Definition: Any process induced by hormones that directly activates any of the steps required for programmed cell death.
axoneme assembly (GO:0035082)
Namespace: biological_process
Definition: The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
Synonyms: axoneme biogenesis; ciliary axoneme assembly; cilium axoneme assembly; cilium axoneme biogenesis; flagellar axoneme assembly; flagellum axoneme assembly
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent.
establishment or maintenance of apical/basal cell polarity (GO:0035088)
Namespace: biological_process
Definition: Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
maintenance of apical/basal cell polarity (GO:0035090)
Namespace: biological_process
Definition: Retaining the established polarization of a cell along its apical/basal axis.
phosphatidylinositol binding (GO:0035091)
Namespace: molecular_function
Definition: Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
Synonyms: phosphoinositide binding
sperm DNA condensation (GO:0035092)
Namespace: biological_process
Definition: The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
Synonyms: sperm chromatin condensation; spermatogenesis, exchange of chromosomal proteins
response to nicotine (GO:0035094)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
behavioral response to nicotine (GO:0035095)
Namespace: biological_process
Definition: Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
Synonyms: behavioural response to nicotine
larval midgut cell programmed cell death (GO:0035096)
Namespace: biological_process
Definition: The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.
Synonyms: larval midgut cell death; programmed cell death of larval midgut cells
histone methyltransferase complex (GO:0035097)
Namespace: cellular_component
Definition: A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.
hemocyte migration (GO:0035099)
Namespace: biological_process
Definition: The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.
Synonyms: arthropod blood cell migration; hemocyte cell migration
ecdysone binding (GO:0035100)
Namespace: molecular_function
Definition: Binding to 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.
FACT complex (GO:0035101)
Namespace: cellular_component
Definition: A histone chaperone complex that facilitates nucleosome disassembly and reassembly upon DNA or RNA polymerase passage.
Synonyms: Facilitates chromatin transcription complex
obsolete sterol regulatory element binding protein cleavage (GO:0035103)
Namespace: biological_process
Definition: OBSOLETE. The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.
Synonyms: SREBP cleavage; sterol depletion response, SREBP cleavage; sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway
Comment: This term was obsoleted because it represents a molecular function.
obsolete sterol regulatory element binding protein import into nucleus (GO:0035105)
Namespace: biological_process
Definition: OBSOLETE. The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.
Synonyms: SREBP import into nucleus; SREBP import into nucleus involved in sterol depletion response; SREBP nuclear translocation; sterol depletion response, SREBP import into nucleus; sterol depletion response, SREBP nuclear translocation; sterol depletion response, sterol regulatory element binding protein import into nucleus; sterol depletion response, sterol regulatory element binding protein nuclear translocation; sterol regulatory element binding protein import into nucleus involved in sterol depletion response; sterol regulatory element binding protein nuclear translocation; sterol regulatory element binding protein nuclear translocation involved in sterol depletion response
Comment: The reason for obsoletion is that all proteins are imported into the nucleus via the same mechanism, so the import of individual proteins should be captured with extensions or by GO-CAM models.
operant conditioning (GO:0035106)
Namespace: biological_process
Definition: Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
Synonyms: instrumental conditioning
appendage morphogenesis (GO:0035107)
Namespace: biological_process
Definition: The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
limb morphogenesis (GO:0035108)
Namespace: biological_process
Definition: The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
Synonyms: limb bud morphogenesis
obsolete imaginal disc-derived limb morphogenesis (GO:0035109)
Namespace: biological_process
Definition: OBSOLETE. The process in which the anatomical structures of limbs that are derived from an imaginal disc are generated and organized. A limb is an appendage of an animal used for locomotion or grasping. An example of this process is found in Drosophila melanogaster.
Synonyms: imaginal disc-derived limb morphogenesis
Comment: This term was made obsolete because the term 'limb' is not widely used in the insect community. In GO, 'limb' is used to describe the vertebrate hindlimbs and forelimbs.
obsolete leg morphogenesis (GO:0035110)
Namespace: biological_process
Definition: OBSOLETE. The process in which the anatomical structures of a leg are generated and organized. A leg is a limb on which an animal walks and stands.
Synonyms: leg morphogenesis
Comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.
genitalia morphogenesis (GO:0035112)
Namespace: biological_process
Definition: The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.
Synonyms: genital morphogenesis
embryonic appendage morphogenesis (GO:0035113)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
imaginal disc-derived appendage morphogenesis (GO:0035114)
Namespace: biological_process
Definition: The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.
embryonic forelimb morphogenesis (GO:0035115)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
Synonyms: embryonic arm morphogenesis
embryonic hindlimb morphogenesis (GO:0035116)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
embryonic pectoral fin morphogenesis (GO:0035118)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
embryonic pelvic fin morphogenesis (GO:0035119)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
post-embryonic appendage morphogenesis (GO:0035120)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
obsolete tail morphogenesis (GO:0035121)
Namespace: biological_process
Definition: OBSOLETE. The process in which the anatomical structures of the tail are generated and organized. The tail is the hindmost part of some animals.
Synonyms: tail morphogenesis
Comment: This term was made obsolete because 'tail' has different meanings in different organisms, and is therefore not a useful grouping term.
embryonic medial fin morphogenesis (GO:0035122)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
Synonyms: embryonic unpaired fin morphogenesis
embryonic dorsal fin morphogenesis (GO:0035123)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
embryonic caudal fin morphogenesis (GO:0035124)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
embryonic anal fin morphogenesis (GO:0035125)
Namespace: biological_process
Definition: The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
post-embryonic genitalia morphogenesis (GO:0035126)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.
Synonyms: post-embryonic genital morphogenesis
post-embryonic limb morphogenesis (GO:0035127)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
post-embryonic forelimb morphogenesis (GO:0035128)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.
post-embryonic pectoral fin morphogenesis (GO:0035130)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
post-embryonic pelvic fin morphogenesis (GO:0035131)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
post-embryonic medial fin morphogenesis (GO:0035132)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
Synonyms: post-embryonic unpaired fin morphogenesis
post-embryonic caudal fin morphogenesis (GO:0035133)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
post-embryonic dorsal fin morphogenesis (GO:0035134)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
post-embryonic anal fin morphogenesis (GO:0035135)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
forelimb morphogenesis (GO:0035136)
Namespace: biological_process
Definition: The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
Synonyms: arm morphogenesis
hindlimb morphogenesis (GO:0035137)
Namespace: biological_process
Definition: The process in which the anatomical structures of the hindlimb are generated and organized.
pectoral fin morphogenesis (GO:0035138)
Namespace: biological_process
Definition: The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.