LiteFold/GO huggingface dataset:
obsolete coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity (GO:0045331)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: coenzyme-M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide + H2 = coenzyme-M + N-(7-mercaptoheptanoyl)threonine O3-phosphate.
Synonyms: coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase activity; coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulphide hydrogenase activity; heterodisulfide reductase activity
Comment: This term was made obsolete because it represents two activities.
phospholipid translocation (GO:0045332)
Namespace: biological_process
Definition: The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
Synonyms: flippase; phospholipid scrambling
Comment: Note that this term describes the transbilayer motion of individual phospholipid molecules, and should not be confused with 'phospholipid scrambling ; GO:0017121'.
cellular respiration (GO:0045333)
Namespace: biological_process
Definition: The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
Synonyms: oxidative metabolic process; oxidative metabolism; respiration
clathrin-coated endocytic vesicle (GO:0045334)
Namespace: cellular_component
Definition: A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
phagocytic vesicle (GO:0045335)
Namespace: cellular_component
Definition: A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
Synonyms: phagosome
clathrin-coated phagocytic vesicle (GO:0045336)
Namespace: cellular_component
Definition: A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
Synonyms: clathrin-coated phagosome
farnesyl diphosphate biosynthetic process (GO:0045337)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
Synonyms: farnesyl diphosphate anabolism; farnesyl diphosphate biosynthesis; farnesyl diphosphate formation; farnesyl diphosphate synthesis
farnesyl diphosphate metabolic process (GO:0045338)
Namespace: biological_process
Definition: The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
Synonyms: farnesyl diphosphate metabolism
farnesyl diphosphate catabolic process (GO:0045339)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.
Synonyms: farnesyl diphosphate breakdown; farnesyl diphosphate catabolism; farnesyl diphosphate degradation
mercury ion binding (GO:0045340)
Namespace: molecular_function
Definition: Binding to a mercury ion (Hg2+).
Synonyms: Hg ion binding; mercury binding
MHC class I biosynthetic process (GO:0045341)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.
Synonyms: major histocompatibility complex class I biosynthesis; major histocompatibility complex class I biosynthetic process; MHC class I anabolism; MHC class I biosynthesis; MHC class I formation; MHC class I synthesis
MHC class II biosynthetic process (GO:0045342)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.
Synonyms: major histocompatibility complex class II biosynthesis; major histocompatibility complex class II biosynthetic process; MHC class II anabolism; MHC class II biosynthesis; MHC class II formation; MHC class II synthesis
regulation of MHC class I biosynthetic process (GO:0045343)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
Synonyms: regulation of major histocompatibility complex class I biosynthesis; regulation of major histocompatibility complex class I biosynthetic process; regulation of MHC class I anabolism; regulation of MHC class I biosynthesis; regulation of MHC class I formation; regulation of MHC class I synthesis
negative regulation of MHC class I biosynthetic process (GO:0045344)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
Synonyms: down regulation of MHC class I biosynthetic process; down-regulation of MHC class I biosynthetic process; downregulation of MHC class I biosynthetic process; inhibition of MHC class I biosynthetic process; negative regulation of major histocompatibility complex class I biosynthesis; negative regulation of major histocompatibility complex class I biosynthetic process; negative regulation of MHC class I anabolism; negative regulation of MHC class I biosynthesis; negative regulation of MHC class I formation; negative regulation of MHC class I synthesis
positive regulation of MHC class I biosynthetic process (GO:0045345)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
Synonyms: activation of MHC class I biosynthetic process; positive regulation of major histocompatibility complex class I biosynthesis; positive regulation of major histocompatibility complex class I biosynthetic process; positive regulation of MHC class I anabolism; positive regulation of MHC class I biosynthesis; positive regulation of MHC class I formation; positive regulation of MHC class I synthesis; stimulation of MHC class I biosynthetic process; up regulation of MHC class I biosynthetic process; up-regulation of MHC class I biosynthetic process; upregulation of MHC class I biosynthetic process
regulation of MHC class II biosynthetic process (GO:0045346)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms: regulation of major histocompatibility complex class II biosynthesis; regulation of major histocompatibility complex class II biosynthetic process; regulation of MHC class II anabolism; regulation of MHC class II biosynthesis; regulation of MHC class II formation; regulation of MHC class II synthesis
negative regulation of MHC class II biosynthetic process (GO:0045347)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms: down regulation of MHC class II biosynthetic process; down-regulation of MHC class II biosynthetic process; downregulation of MHC class II biosynthetic process; inhibition of MHC class II biosynthetic process; negative regulation of major histocompatibility complex class II biosynthesis; negative regulation of major histocompatibility complex class II biosynthetic process; negative regulation of MHC class II anabolism; negative regulation of MHC class II biosynthesis; negative regulation of MHC class II formation; negative regulation of MHC class II synthesis
positive regulation of MHC class II biosynthetic process (GO:0045348)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
Synonyms: activation of MHC class II biosynthetic process; positive regulation of major histocompatibility complex class II biosynthesis; positive regulation of major histocompatibility complex class II biosynthetic process; positive regulation of MHC class II anabolism; positive regulation of MHC class II biosynthesis; positive regulation of MHC class II formation; positive regulation of MHC class II synthesis; stimulation of MHC class II biosynthetic process; up regulation of MHC class II biosynthetic process; up-regulation of MHC class II biosynthetic process; upregulation of MHC class II biosynthetic process
interleukin-1 type I receptor antagonist activity (GO:0045352)
Namespace: molecular_function
Definition: Blocks the binding of interleukin-1 to interleukin-1 type I receptors.
Synonyms: IL-1ra type I
interleukin-1 type II receptor antagonist activity (GO:0045353)
Namespace: molecular_function
Definition: Blocks the binding of interleukin-1 to interleukin-1 type II receptors.
Synonyms: IL-1ra type II
obsolete enzyme active site formation via (phospho-5'-guanosine)-L-histidine (GO:0045427)
Namespace: biological_process
Definition: OBSOLETE. The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.
Comment: This term was obsoleted because it represents a reaction intermediate, not a biological process, see PMID:10529169.
regulation of nitric oxide biosynthetic process (GO:0045428)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
Synonyms: regulation of nitric oxide anabolism; regulation of nitric oxide biosynthesis; regulation of nitric oxide formation; regulation of nitric oxide synthesis
positive regulation of nitric oxide biosynthetic process (GO:0045429)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
Synonyms: activation of nitric oxide biosynthetic process; positive regulation of nitric oxide anabolism; positive regulation of nitric oxide biosynthesis; positive regulation of nitric oxide formation; positive regulation of nitric oxide synthesis; stimulation of nitric oxide biosynthetic process; up regulation of nitric oxide biosynthetic process; up-regulation of nitric oxide biosynthetic process; upregulation of nitric oxide biosynthetic process
chalcone isomerase activity (GO:0045430)
Namespace: molecular_function
Definition: Catalysis of the reaction: a chalcone = a flavanone.
Synonyms: chalcone--flavonone isomerase activity; chalcone-flavanone isomerase activity; flavanone lyase (decyclizing)
flavonol synthase activity (GO:0045431)
Namespace: molecular_function
Definition: Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
Synonyms: dihydroflavonol,2-oxoglutarate:oxygen oxidoreductase activity; flavonoid 2-oxoglutarate-dependent dioxygenase activity; FLS activity
negative regulation of female receptivity, post-mating (GO:0045434)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.
Synonyms: down regulation of female receptivity, post-mating; down-regulation of female receptivity, post-mating; downregulation of female receptivity, post-mating; inhibition of female receptivity, post-mating
lycopene epsilon cyclase activity (GO:0045435)
Namespace: molecular_function
Definition: Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).
Synonyms: lycopene cyclase
lycopene beta cyclase activity (GO:0045436)
Namespace: molecular_function
Definition: Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.
Synonyms: crtL; lycopene cyclase
uridine nucleosidase activity (GO:0045437)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + uridine = ribofuranose + uracil.
Synonyms: uridine hydrolase activity; uridine ribohydrolase activity
obsolete delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity (GO:0045438)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
Synonyms: ACV synthetase activity
Comment: The reason for obsoletion is that this term is equivalent to N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity.
isopenicillin-N epimerase activity (GO:0045439)
Namespace: molecular_function
Definition: Catalysis of the reaction: isopenicillin N = penicillin N.
Synonyms: isopenicillin N epimerase activity; penicillin-N 5-amino-5-carboxypentanoyl-epimerase activity
deacetoxycephalosporin-C hydroxylase activity (GO:0045442)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O2 = CO2 + deacetylcephalosporin C + succinate.
Synonyms: 3'-methylcephem hydroxylase activity; beta-lactam hydroxylase activity; DACS; DAOC hydroxylase activity; deacetoxycephalosporin C hydroxylase activity; deacetoxycephalosporin-C,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity; deacetylcephalosporin C synthase activity
juvenile hormone secretion (GO:0045443)
Namespace: biological_process
Definition: The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
fat cell differentiation (GO:0045444)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
Synonyms: adipocyte cell differentiation; adipocyte differentiation; adipogenesis; adipose cell differentiation
myoblast differentiation (GO:0045445)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
Synonyms: myoblast cell differentiation
mitotic cell cycle, embryonic (GO:0045448)
Namespace: biological_process
Definition: The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.
bicoid mRNA localization (GO:0045450)
Namespace: biological_process
Definition: Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.
Synonyms: bicoid mRNA localisation; establishment and maintenance of bicoid mRNA localization
pole plasm oskar mRNA localization (GO:0045451)
Namespace: biological_process
Definition: Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
Synonyms: establishment and maintenance of oskar mRNA localization in pole plasm; establishment and maintenance of pole plasm oskar mRNA localization; oocyte pole plasm oskar mRNA localization; pole plasm oskar mRNA localisation
bone resorption (GO:0045453)
Namespace: biological_process
Definition: The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
cell redox homeostasis (GO:0045454)
Namespace: biological_process
Definition: Any process that maintains the redox environment of a cell or compartment within a cell.
Synonyms: regulation of cell redox homeostasis; regulation of redox homeostasis
ecdysteroid metabolic process (GO:0045455)
Namespace: biological_process
Definition: The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.
Synonyms: ecdysteroid metabolism
ecdysteroid biosynthetic process (GO:0045456)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
Synonyms: ecdysteroid anabolism; ecdysteroid biosynthesis; ecdysteroid formation; ecdysteroid synthesis
ecdysteroid secretion (GO:0045457)
Namespace: biological_process
Definition: The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
recombination within rDNA repeats (GO:0045458)
Namespace: biological_process
Definition: Genetic recombination within the DNA of the genes coding for ribosomal RNA.
Synonyms: recombination within ribosomal DNA repeats
Comment: Note that this term was reinstated from obsolete.
obsolete iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide (GO:0045459)
Namespace: biological_process
Definition: OBSOLETE. The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.
Synonyms: iron incorporation into iron-sulphur cluster via tetrakis-L-cysteinyl triiron tetrasulphide
Comment: This term was obsoleted because it represents a molecular function.
sterigmatocystin metabolic process (GO:0045460)
Namespace: biological_process
Definition: The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
Synonyms: sterigmatocystin metabolism
sterigmatocystin biosynthetic process (GO:0045461)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
Synonyms: sterigmatocystin anabolism; sterigmatocystin biosynthesis; sterigmatocystin formation; sterigmatocystin synthesis
R8 cell development (GO:0045463)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.
R8 cell fate specification (GO:0045464)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
R8 cell differentiation (GO:0045465)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.
R7 cell development (GO:0045467)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.
regulation of R8 cell spacing in compound eye (GO:0045468)
Namespace: biological_process
Definition: Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.
Synonyms: R8 cell spacing in compound eye; regulation of R8 spacing
negative regulation of R8 cell spacing in compound eye (GO:0045469)
Namespace: biological_process
Definition: Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.
Synonyms: down regulation of R8 spacing; down-regulation of R8 spacing; downregulation of R8 spacing; inhibition of R8 spacing
R8 cell-mediated photoreceptor organization (GO:0045470)
Namespace: biological_process
Definition: The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.
Synonyms: R8-mediated photoreceptor organisation
response to ethanol (GO:0045471)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
obsolete response to ethanol (sensu Insecta) (GO:0045473)
Namespace: biological_process
Definition: OBSOLETE. A change in state or activity of an insect (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
Synonyms: response to ethanol (sensu Insecta)
Comment: This term was made obsolete because there is no clear difference between the sensu Insecta term and the generic term.
locomotor rhythm (GO:0045475)
Namespace: biological_process
Definition: The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
Synonyms: circadian locomotor activity rhythm
nurse cell apoptotic process (GO:0045476)
Namespace: biological_process
Definition: Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
Synonyms: apoptosis of nurse cells; invertebrate nurse cell apoptosis; nurse cell apoptosis; nurse cell programmed cell death by apoptosis; programmed cell death of nurse cells by apoptosis
regulation of nurse cell apoptotic process (GO:0045477)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.
Synonyms: regulation of nurse cell apoptosis
fusome organization (GO:0045478)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.
Synonyms: fusome organisation; fusome organization and biogenesis
vesicle targeting to fusome (GO:0045479)
Namespace: biological_process
Definition: The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.
Synonyms: vesicle-fusome targeting
galactose oxidase activity (GO:0045480)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + H2O2.
Synonyms: beta-galactose oxidase activity; D-galactose oxidase activity; D-galactose:oxygen 6-oxidoreductase activity
6-endo-hydroxycineole dehydrogenase activity (GO:0045481)
Namespace: molecular_function
Definition: Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.
Synonyms: 6-endo-hydroxycineole:NAD+ 6-oxidoreductase activity
aristolochene synthase activity (GO:0045483)
Namespace: molecular_function
Definition: Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.
Synonyms: 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming); sesquiterpene cyclase activity; trans,trans-farnesyl diphosphate aristolochene-lyase activity; trans,trans-farnesyl-diphosphate diphosphate-lyase (cyclizing, aristolochene-forming)
L-lysine:2-oxoglutarate 6-transaminase activity (GO:0045484)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.
Synonyms: L-lysine 6-transaminase activity; L-lysine aminotransferase activity; L-lysine transaminase activity; L-lysine-alpha-ketoglutarate 6-aminotransferase activity; L-lysine-alpha-ketoglutarate aminotransferase activity; L-lysine:2-oxoglutarate 6-aminotransferase activity; lysine 6-aminotransferase activity; lysine epsilon-aminotransferase activity; lysine epsilon-transaminase activity; lysine:2-ketoglutarate 6-aminotransferase activity
omega-6 fatty acid desaturase activity (GO:0045485)
Namespace: molecular_function
Definition: Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.