LiteFold/GO huggingface dataset:
oxysterol transfer activity (GO:0120021)
Namespace: molecular_function
Definition: Removes oxysterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: intermembrane oxysterol transfer activity; oxysterol carrier activity
glucagon family peptide binding (GO:0120022)
Namespace: molecular_function
Definition: Binding to a member of the glucagon family peptide hormone (e.g. glucagon, glucagon-like peptides, oxyntomodulin, glicentin, ADCYAP1, GHRH, secretin, VIP, GIP).
Synonyms: glucagon binding; glucagon-like peptide binding
somatostatin binding (GO:0120023)
Namespace: molecular_function
Definition: Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin.
plasma membrane bounded cell projection (GO:0120025)
Namespace: cellular_component
Definition: A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
host cell uropod (GO:0120026)
Namespace: cellular_component
Definition: A host cell membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
Synonyms: host cell uropodium
obsolete regulation of osmosensory signaling pathway (GO:0120027)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete negative regulation of osmosensory signaling pathway (GO:0120028)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of osmosensory signaling pathway.
Comment: This term was obsoleted because it is an unnecessary grouping term.
proton export across plasma membrane (GO:0120029)
Namespace: biological_process
Definition: The directed movement of hydrogen ions (protons) from inside a cell, across the plasma membrane and into the extracellular region.
Synonyms: hydrogen ion export across plasma membrane; hydrogen ion export from cell; proton export from cell
positive regulation of cilium beat frequency involved in ciliary motility (GO:0120030)
Namespace: biological_process
Definition: Any process that activates or increases the frequency of cilium beating involved in ciliary motility.
plasma membrane bounded cell projection assembly (GO:0120031)
Namespace: biological_process
Definition: Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon.
Synonyms: eupodium
regulation of plasma membrane bounded cell projection assembly (GO:0120032)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly.
negative regulation of plasma membrane bounded cell projection assembly (GO:0120033)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.
positive regulation of plasma membrane bounded cell projection assembly (GO:0120034)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.
regulation of plasma membrane bounded cell projection organization (GO:0120035)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.
plasma membrane bounded cell projection organization (GO:0120036)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon.
obsolete plasma membrane bounded cell projection part (GO:0120038)
Namespace: cellular_component
Definition: OBSOLETE. Any constituent part of a plasma membrane bounded cell projection, a prolongation or process extending from a cell, e.g. a cilium or axon.
plasma membrane bounded cell projection morphogenesis (GO:0120039)
Namespace: biological_process
Definition: The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized.
regulation of macrophage proliferation (GO:0120040)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of macrophage proliferation.
positive regulation of macrophage proliferation (GO:0120041)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of macrophage proliferation.
negative regulation of macrophage proliferation (GO:0120042)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage proliferation.
stereocilium shaft (GO:0120043)
Namespace: cellular_component
Definition: The shaft comprises the majority of the length of the stereocilium. This region is notable for the extreme stability of actin filaments, which are highly crosslinked into a parallel bundle.
stereocilium base (GO:0120044)
Namespace: cellular_component
Definition: The tapered base of the stereocilium adjacent to where it joins the hair cell body. This region contains a rootlet comprised of bundled actin filaments which spans the joint and stabilizes the stereocilium.
Synonyms: stereocilium taper
stereocilium maintenance (GO:0120045)
Namespace: biological_process
Definition: The organization process that preserves a stereocilium in a stable functional or structural state.
regulation of protein localization to medial cortical node (GO:0120046)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein localization to a medial cortical node.
positive regulation of protein localization to medial cortical node (GO:0120047)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein localization to a medial cortical node.
U6 snRNA (adenine(43)-N6)-methyltransferase activity (GO:0120048)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosine in U6 snRNA + S-adenosyl-L-methionine = H+ + N(6)-methyladenosine in U6 snRNA + S-adenosyl-L-homocysteine.
Synonyms: U6 snRNA m(6)A methyltransferase activity
snRNA (adenine-N6)-methylation (GO:0120049)
Namespace: biological_process
Definition: The posttranscriptional N6-methylation of an adenine residue in an snRNA molecule.
intestinal motility (GO:0120054)
Namespace: biological_process
Definition: Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).
small intestinal transit (GO:0120055)
Namespace: biological_process
Definition: Migration of ingested material along the length of the small intestine.
Synonyms: small bowel transit; small intestine transit
large intestinal transit (GO:0120056)
Namespace: biological_process
Definition: Migration of ingested material along the length of the large intestine.
Synonyms: colon transit; colonic transit; large bowel transit; large intestine transit
regulation of small intestinal transit (GO:0120057)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
Synonyms: regulation of small bowel transit; regulation of small intestine transit
positive regulation of small intestinal transit (GO:0120058)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
Synonyms: positive regulation of small bowel transit; positive regulation of small intestine transit
negative regulation of small intestinal transit (GO:0120059)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.
Synonyms: negative regulation of small bowel transit; negative regulation of small intestine transit
regulation of gastric emptying (GO:0120060)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
Synonyms: regulation of small bowel emptying; regulation of small intestine emptying
negative regulation of gastric emptying (GO:0120061)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
stomach smooth muscle contraction (GO:0120063)
Namespace: biological_process
Definition: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs throughout the length of the stomach.
stomach pylorus smooth muscle contraction (GO:0120064)
Namespace: biological_process
Definition: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the most distal part of the stomach.
pyloric antrum smooth muscle contraction (GO:0120065)
Namespace: biological_process
Definition: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the widest part of the pylorus that is continuous with the body of the stomach.
Synonyms: antrum smooth muscle contraction
pyloric canal smooth muscle contraction (GO:0120066)
Namespace: biological_process
Definition: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.
pyloric sphincter smooth muscle contraction (GO:0120067)
Namespace: biological_process
Definition: A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.
regulation of stomach fundus smooth muscle contraction (GO:0120068)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.
positive regulation of stomach fundus smooth muscle contraction (GO:0120069)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.
negative regulation of stomach fundus smooth muscle contraction (GO:0120070)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of any stomach fundus smooth muscle contraction.
regulation of pyloric antrum smooth muscle contraction (GO:0120071)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
positive regulation of pyloric antrum smooth muscle contraction (GO:0120072)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
negative regulation of pyloric antrum smooth muscle contraction (GO:0120073)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.
regulation of endocardial cushion cell differentiation (GO:0120074)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cell differentiation, the process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.
positive regulation of endocardial cushion cell differentiation (GO:0120075)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of endocardial cushion cell differentiation.
negative regulation of endocardial cushion cell differentiation (GO:0120076)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of endocardial cushion cell differentiation.
angiogenic sprout fusion (GO:0120077)
Namespace: biological_process
Definition: The connection of an angiogenic sprout to another vessel or sprout during the formation of vascular networks by sprouting angiogenesis.
Synonyms: blood vessel anastomosis
cell adhesion involved in sprouting angiogenesis (GO:0120078)
Namespace: biological_process
Definition: The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.
Synonyms: cell adhesion involved in blood vessel anastomosis; cell adhesion involved in vascular anastomosis
obsolete regulation of microfilament motor activity (GO:0120079)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of microfilament motor activity.
Synonyms: regulation of actin filament motor activity; regulation of actin-activated ATPase activity; regulation of actin-dependent ATPase activity; regulation of actin-filament motor activity; regulation of muscle motor activity; regulation of myosin ATPase activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of microfilament motor activity (GO:0120080)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of microfilament motor activity.
Synonyms: down regulation of actin-activated ATPase activity; down regulation of actin-dependent ATPase activity; inhibition of actin-activated ATPase activity; inhibition of actin-dependent ATPase activity; negative regulation of actin filament motor activity; negative regulation of actin-activated ATPase activity; negative regulation of actin-dependent ATPase activity; negative regulation of actin-filament motor activity; negative regulation of muscle motor activity; negative regulation of myosin ATPase activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of microfilament motor activity (GO:0120081)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of microfilament motor activity.
Synonyms: activation of actin-activated ATPase activity; activation of actin-dependent ATPase activity; positive regulation of actin filament motor activity; positive regulation of actin-activated ATPase activity; positive regulation of actin-dependent ATPase activity; positive regulation of actin-filament motor activity; positive regulation of muscle motor activity; positive regulation of myosin ATPase activity; upregulation of actin-dependent ATPase activity
Comment: This term was obsoleted because it represents a molecular function.
smooth endoplasmic reticulum cisterna (GO:0120082)
Namespace: cellular_component
Definition: A subcompartment of the smooth endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.
endothelial tip cell filopodium assembly (GO:0120084)
Namespace: biological_process
Definition: The assembly of a filopodium, a thin, stiff protrusion extended by the endothelial tip cell of a vascular sprout.
(3S)-(+)-asterisca-2(9),6-diene synthase activity (GO:0120086)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate.
Synonyms: asterisca-2(9),6-diene synthase activity
jasmonic acid hydrolase activity (GO:0120091)
Namespace: molecular_function
Definition: Catalysis of the reaction: jasmonate + 2-oxoglutarate + O2 = (1R,2R)-12-hydroxyjasmonate + succinate + CO2.
Synonyms: 2-oxoglutarate dioxygenase
(2E)-butenoyl-CoA hydratase activity (GO:0120092)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O. (2E)-butenoyl-CoA is also known as crotonoyl-CoA.
Synonyms: crotonyl-CoA hydratase activity
regulation of peptidyl-lysine crotonylation (GO:0120093)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of crotonylation of a lysine residue in a protein.
negative regulation of peptidyl-lysine crotonylation (GO:0120094)
Namespace: biological_process
Definition: Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.
glycosylphosphatidylinositol-mannosyltransferase II complex (GO:0120097)
Namespace: cellular_component
Definition: A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.
Synonyms: GPI-MT-I complex
procentriole (GO:0120098)
Namespace: cellular_component
Definition: A cellular structure that is the site of a developing centriole, which will become a microtubule organizing center. During the canonical pathway of centriole duplication that occurs during the cell division cycle, procentrioles grow at the proximal ends of both mother and daughter centrioles. In the newly divided cells, the original mother and daughter centrioles become mother centrioles while the procentrioles become the new daughter centrioles. Procentrioles can also arise from de novo pathways that occur in multiciliated cells. In ciliated epithelial cells, numerous procentrioles arise form electron dense material referred to as fibrous granules and deuterosomes. The pathway of procentriole formation in multiciliated protists appears to be similar to that in mammalian multiciliated epithelium. In sperm of primitive land plants, multiple procentrioles are formed from a blepharoplast giving rise to multicilated sperm cells.
procentriole replication complex (GO:0120099)
Namespace: cellular_component
Definition: A protein complex that acts as a chaperone or scaffold for centriolar proteins during the maturation of the procentriole. Some of its members may become integrated into the growing centriole. Examples are the CPAP(CENPJ)-STIL complex, CEP192-PLK4 complex or CEP152-PLK4 complex in vertebrates.
bacterial-type flagellum motor (GO:0120100)
Namespace: cellular_component
Definition: A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. The motor consists of a membrane-anchored rotor complex surrounded by one or more stator complexes in the cytoplasmic membrane. The stator consists of a hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. Examples are the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species. The rotor complex consists of a membrane-anchored ring and the motor switch complex, which controls the direction of flagellar rotation.
bacterial-type flagellum stator complex (GO:0120101)
Namespace: cellular_component
Definition: A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species.
Synonyms: bacterial-type flagellum motor force generator complex; bacterial-type flagellum torque generator complex
bacterial-type flagellum secretion apparatus (GO:0120102)
Namespace: cellular_component
Definition: A part of the bacterial-type flagellum that is located at the cytoplasmic side of the MS ring and composed of six membrane proteins (FlhA, FlhB, FliP, FliQ, FliR, and FliO, or orthologs thereof) and three soluble proteins (FliI, FliH, and FliJ, or orthologs thereof) in the cytoplasm. It is responsible for secretion of flagellar type III protein substrates, including the proteins of the flagellar rod, hook, and filament.
Synonyms: bacterial-type flagellum export apparatus
centriolar subdistal appendage (GO:0120103)
Namespace: cellular_component
Definition: A protein complex which assembles on the mother centriole during cilium formation, adjacent and proximal to a centriolar distal appendage. In human, it contains ODF2, CNTRL, NIN, CCDC120c and CCDC68.
Synonyms: subdistal appendage of basal body; subdistal appendage of centriole; subdistal appendage of mother centriole
mitotic actomyosin contractile ring, proximal layer (GO:0120104)
Namespace: cellular_component
Definition: The region of the mitotic actomyosin ring adjacent to the plasma membrane where membrane bound scaffolds are located.
Synonyms: actomyosin contractile ring, proximal layer
mitotic actomyosin contractile ring, intermediate layer (GO:0120105)
Namespace: cellular_component
Definition: The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer.
Synonyms: actomyosin contractile ring, intermediate layer
mitotic actomyosin contractile ring, distal actin filament layer (GO:0120106)
Namespace: cellular_component
Definition: The region of the mitotic actomyosin ring containing actin filaments and cross linkers, myosin motors, and connections to the plasma membrane through the intermediate layer. It is further from the plasma membrane than the intermediate layer which it is adjacent to.
Synonyms: actomyosin contractile ring, distal actin filament layer
bacterial-type flagellum rotor complex (GO:0120107)
Namespace: cellular_component
Definition: The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.
mitotic telomere clustering and tethering at nuclear periphery (GO:0120109)
Namespace: biological_process
Definition: The process in which the telomeres are gathered together to a small number of foci per chromosome (usually one per chromosome or fewer), and moved to and tethered at the nuclear periphery, as part of a mitotic cell cycle.
interphase mitotic telomere clustering (GO:0120110)
Namespace: biological_process
Definition: The process whereby the mitotic telomeres are gathered together during, or prior to, attachment to the nuclear envelope.
Synonyms: mitotic telomere clustering during interphase
Comment: It is likely that both intra chromosome telomere clustering and inter-chromosome occur because a single focus is sometimes observed, although this has yet to be proven.