LiteFold/GO huggingface dataset:
negative regulation of leucine import in response to ammonium ion (GO:0060360)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.
Synonyms: negative regulation of leucine uptake in response to ammonium ion
flight (GO:0060361)
Namespace: biological_process
Definition: Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
obsolete flight involved in flight behavior (GO:0060362)
Namespace: biological_process
Definition: OBSOLETE. Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
cranial suture morphogenesis (GO:0060363)
Namespace: biological_process
Definition: The process in which any suture between cranial bones is generated and organized.
frontal suture morphogenesis (GO:0060364)
Namespace: biological_process
Definition: The process in which the frontal suture is generated and organized.
Synonyms: interfrontal suture morphogenesis
coronal suture morphogenesis (GO:0060365)
Namespace: biological_process
Definition: The process in which the coronal suture is generated and organized.
lambdoid suture morphogenesis (GO:0060366)
Namespace: biological_process
Definition: The process in which the lambdoid suture is generated and organized.
sagittal suture morphogenesis (GO:0060367)
Namespace: biological_process
Definition: The process in which the sagittal suture is generated and organized.
regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060368)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway..
Synonyms: regulation of Fc receptor mediated stimulatory signalling pathway
positive regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060369)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway.
Synonyms: positive regulation of Fc receptor mediated stimulatory signalling pathway
susceptibility to T cell mediated cytotoxicity (GO:0060370)
Namespace: biological_process
Definition: The process of causing a cell to become susceptible to T cell mediated cytotoxicity.
regulation of atrial cardiac muscle cell membrane repolarization (GO:0060372)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.
Synonyms: atrial repolarization; electrocardiogram QRS complex; regulation of atrial cardiac muscle cell repolarization; regulation of atrial cardiomyocyte membrane repolarization
regulation of ventricular cardiac muscle cell membrane depolarization (GO:0060373)
Namespace: biological_process
Definition: Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.
Synonyms: electrocardiogram QRS complex; regulation of ventricular cardiomyocyte membrane depolarization; ventricular depolarization
mast cell differentiation (GO:0060374)
Namespace: biological_process
Definition: The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
regulation of mast cell differentiation (GO:0060375)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
positive regulation of mast cell differentiation (GO:0060376)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
negative regulation of mast cell differentiation (GO:0060377)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
regulation of brood size (GO:0060378)
Namespace: biological_process
Definition: Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
cardiac muscle cell myoblast differentiation (GO:0060379)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
Synonyms: cardiac myoblast differentiation; myocardial precursor cell differentiation
obsolete regulation of single-stranded telomeric DNA binding (GO:0060380)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.
Synonyms: regulation of telomeric ssDNA binding
Comment: This term was obsoleted because it represents a molecular function.
regulation of DNA strand elongation (GO:0060382)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
positive regulation of DNA strand elongation (GO:0060383)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
innervation (GO:0060384)
Namespace: biological_process
Definition: The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
axonogenesis involved in innervation (GO:0060385)
Namespace: biological_process
Definition: The neurite development process that generates a long process of a neuron, as it invades a target tissue.
synapse assembly involved in innervation (GO:0060386)
Namespace: biological_process
Definition: The assembly of a synapse within a target tissue in which a nerve is invading.
Synonyms: synapse biogenesis involved in innervation; synaptogenesis involved in innervation
fertilization envelope (GO:0060387)
Namespace: cellular_component
Definition: A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.
Synonyms: fertilization membrane
vitelline envelope (GO:0060388)
Namespace: cellular_component
Definition: A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.
Synonyms: fertilization membrane
obsolete pathway-restricted SMAD protein phosphorylation (GO:0060389)
Namespace: biological_process
Definition: OBSOLETE. The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
Synonyms: pathway restricted SMAD protein phosphorylation; R-SMAD protein phosphorylation; receptor regulated SMAD protein phosphorylation; receptor-regulated SMAD protein phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
regulation of SMAD protein signal transduction (GO:0060390)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of SMAD protein signal transduction.
Synonyms: regulation of SMAD protein nuclear translocation; SMAD protein import into nucleus
negative regulation of SMAD protein signal transduction (GO:0060392)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of the SMAD protein signaling pathway.
Synonyms: negative regulation of SMAD protein import into nucleus; negative regulation of SMAD protein nuclear translocation
obsolete regulation of pathway-restricted SMAD protein phosphorylation (GO:0060393)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
Comment: This term was obsoleted because it represents a molecular function.
obsolete negative regulation of pathway-restricted SMAD protein phosphorylation (GO:0060394)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
Comment: This term was obsoleted because it represents a molecular function.
SMAD protein signal transduction (GO:0060395)
Namespace: biological_process
Definition: An intracellular signaling cassette that starts with the activation of a SMAD protein, leading to the formation of a complex with co-SMADs, which translocates to the nucleus and regulates transcription of specific target genes.
Comment: Note that the upstream receptor and its ligand regulate the pathway (and are not part of the SMAD pathway), since it is an intracellular signaling pathway.
growth hormone receptor signaling pathway (GO:0060396)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
Synonyms: cellular response to growth hormone; GH receptor signaling pathway; growth hormone receptor signalling pathway
growth hormone receptor signaling pathway via JAK-STAT (GO:0060397)
Namespace: biological_process
Definition: The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
Synonyms: JAK-STAT cascade involved in growth hormone signalling pathway
regulation of growth hormone receptor signaling pathway (GO:0060398)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
Synonyms: regulation of growth hormone receptor signalling pathway
positive regulation of growth hormone receptor signaling pathway (GO:0060399)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
Synonyms: positive regulation of growth hormone receptor signalling pathway
negative regulation of growth hormone receptor signaling pathway (GO:0060400)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
Synonyms: negative regulation of growth hormone receptor signalling pathway
calcium ion transport into cytosol (GO:0060402)
Namespace: biological_process
Definition: The directed movement of calcium ions (Ca2+) into the cytosol.
axonemal microtubule depolymerization (GO:0060404)
Namespace: biological_process
Definition: The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
regulation of penile erection (GO:0060405)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
positive regulation of penile erection (GO:0060406)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
negative regulation of penile erection (GO:0060407)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
regulation of acetylcholine metabolic process (GO:0060408)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
positive regulation of acetylcholine metabolic process (GO:0060409)
Namespace: biological_process
Definition: Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
cardiac septum morphogenesis (GO:0060411)
Namespace: biological_process
Definition: The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.
Synonyms: heart septum morphogenesis
ventricular septum morphogenesis (GO:0060412)
Namespace: biological_process
Definition: The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
Synonyms: interventricular septum morphogenesis
atrial septum morphogenesis (GO:0060413)
Namespace: biological_process
Definition: The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
Synonyms: interatrial septum morphogenesis
aorta smooth muscle tissue morphogenesis (GO:0060414)
Namespace: biological_process
Definition: The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
muscle tissue morphogenesis (GO:0060415)
Namespace: biological_process
Definition: The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.
response to growth hormone (GO:0060416)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
Synonyms: response to growth hormone stimulus
yolk (GO:0060417)
Namespace: cellular_component
Definition: The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.
yolk plasma (GO:0060418)
Namespace: cellular_component
Definition: Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.
heart growth (GO:0060419)
Namespace: biological_process
Definition: The increase in size or mass of the heart.
regulation of heart growth (GO:0060420)
Namespace: biological_process
Definition: Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
positive regulation of heart growth (GO:0060421)
Namespace: biological_process
Definition: Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
peptidyl-dipeptidase inhibitor activity (GO:0060422)
Namespace: molecular_function
Definition: Binds to and stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.
foregut regionalization (GO:0060423)
Namespace: biological_process
Definition: The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.
lung field specification (GO:0060424)
Namespace: biological_process
Definition: The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.
Synonyms: lung specification
lung morphogenesis (GO:0060425)
Namespace: biological_process
Definition: The process in which the anatomical structures of the lung are generated and organized.
lung vasculature development (GO:0060426)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.
Synonyms: pulmonary vasculature development
lung connective tissue development (GO:0060427)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.
Synonyms: pulmonary connective tissue development
lung epithelium development (GO:0060428)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
Synonyms: pulmonary epithelium development
epithelium development (GO:0060429)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
lung saccule development (GO:0060430)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.
Synonyms: lung saccular development
primary lung bud formation (GO:0060431)
Namespace: biological_process
Definition: The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.
Synonyms: lung formation
lung pattern specification process (GO:0060432)
Namespace: biological_process
Definition: Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.
bronchus development (GO:0060433)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.
bronchus morphogenesis (GO:0060434)
Namespace: biological_process
Definition: The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.
bronchiole development (GO:0060435)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
bronchiole morphogenesis (GO:0060436)
Namespace: biological_process
Definition: The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
lung growth (GO:0060437)
Namespace: biological_process
Definition: The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.