LiteFold/GO huggingface dataset:
neural rod formation (GO:0014023)
Namespace: biological_process
Definition: The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.
neural keel formation (GO:0014025)
Namespace: biological_process
Definition: The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.
notochord formation (GO:0014028)
Namespace: biological_process
Definition: The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.
neural crest formation (GO:0014029)
Namespace: biological_process
Definition: The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.
mesenchymal cell fate commitment (GO:0014030)
Namespace: biological_process
Definition: The process in which a cell becomes committed to become a mesenchymal cell.
mesenchymal cell development (GO:0014031)
Namespace: biological_process
Definition: The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
neural crest cell development (GO:0014032)
Namespace: biological_process
Definition: The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
neural crest cell differentiation (GO:0014033)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
neural crest cell fate commitment (GO:0014034)
Namespace: biological_process
Definition: The process in which a cell becomes committed to become a neural crest cell.
neural crest cell fate determination (GO:0014035)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.
neural crest cell fate specification (GO:0014036)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
Schwann cell differentiation (GO:0014037)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
regulation of Schwann cell differentiation (GO:0014038)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of Schwann cell differentiation.
negative regulation of Schwann cell differentiation (GO:0014039)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.
Synonyms: down regulation of Schwann cell differentiation; down-regulation of Schwann cell differentiation; downregulation of Schwann cell differentiation; inhibition of Schwann cell differentiation
positive regulation of Schwann cell differentiation (GO:0014040)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.
Synonyms: activation of Schwann cell differentiation; stimulation of Schwann cell differentiation; up regulation of Schwann cell differentiation; up-regulation of Schwann cell differentiation; upregulation of Schwann cell differentiation
regulation of neuron maturation (GO:0014041)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.
positive regulation of neuron maturation (GO:0014042)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of neuron maturation.
Synonyms: activation of neuron maturation; stimulation of neuron maturation; up regulation of neuron maturation; up-regulation of neuron maturation; upregulation of neuron maturation
negative regulation of neuron maturation (GO:0014043)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
Synonyms: down regulation of neuron maturation; down-regulation of neuron maturation; downregulation of neuron maturation; inhibition of neuron maturation
Schwann cell development (GO:0014044)
Namespace: biological_process
Definition: The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
establishment of endothelial blood-brain barrier (GO:0014045)
Namespace: biological_process
Definition: Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
Synonyms: establishment of endothelial BBB; establishment of endothelial blood/brain barrier
dopamine secretion (GO:0014046)
Namespace: biological_process
Definition: The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.
glutamate secretion (GO:0014047)
Namespace: biological_process
Definition: The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.
regulation of glutamate secretion (GO:0014048)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the controlled release of glutamate.
positive regulation of glutamate secretion (GO:0014049)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
Synonyms: activation of glutamate secretion; stimulation of glutamate secretion; up regulation of glutamate secretion; up-regulation of glutamate secretion; upregulation of glutamate secretion
negative regulation of glutamate secretion (GO:0014050)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
Synonyms: down regulation of glutamate secretion; down-regulation of glutamate secretion; downregulation of glutamate secretion; inhibition of glutamate secretion
gamma-aminobutyric acid secretion (GO:0014051)
Namespace: biological_process
Definition: The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
Synonyms: GABA secretion
regulation of gamma-aminobutyric acid secretion (GO:0014052)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
Synonyms: regulation of GABA secretion
negative regulation of gamma-aminobutyric acid secretion (GO:0014053)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
Synonyms: down regulation of gamma-aminobutyric acid secretion; down-regulation of gamma-aminobutyric acid secretion; downregulation of gamma-aminobutyric acid secretion; inhibition of gamma-aminobutyric acid secretion; negative regulation of GABA secretion
positive regulation of gamma-aminobutyric acid secretion (GO:0014054)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
Synonyms: activation of gamma-aminobutyric acid secretion; positive regulation of GABA secretion; stimulation of gamma-aminobutyric acid secretion; up regulation of gamma-aminobutyric acid secretion; up-regulation of gamma-aminobutyric acid secretion; upregulation of gamma-aminobutyric acid secretion
regulation of acetylcholine secretion, neurotransmission (GO:0014056)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
positive regulation of acetylcholine secretion, neurotransmission (GO:0014057)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
Synonyms: activation of acetylcholine secretion; stimulation of acetylcholine secretion; up regulation of acetylcholine secretion; up-regulation of acetylcholine secretion; upregulation of acetylcholine secretion
negative regulation of acetylcholine secretion, neurotransmission (GO:0014058)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.
Synonyms: down regulation of acetylcholine secretion; down-regulation of acetylcholine secretion; downregulation of acetylcholine secretion; inhibition of acetylcholine secretion
regulation of dopamine secretion (GO:0014059)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
regulation of epinephrine secretion (GO:0014060)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.
Synonyms: regulation of adrenaline secretion
regulation of norepinephrine secretion (GO:0014061)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.
Synonyms: regulation of noradrenaline secretion
negative regulation of serotonin secretion (GO:0014063)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.
Synonyms: down regulation of serotonin secretion; down-regulation of serotonin secretion; downregulation of serotonin secretion; inhibition of serotonin secretion; positive regulation of serotonin release
positive regulation of serotonin secretion (GO:0014064)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.
Synonyms: activation of serotonin secretion; positive regulation of serotonin release; stimulation of serotonin secretion; up regulation of serotonin secretion; up-regulation of serotonin secretion; upregulation of serotonin secretion
obsolete phosphatidylinositol 3-kinase signaling (GO:0014065)
Namespace: biological_process
Definition: OBSOLETE. A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
Synonyms: phosphatidylinositol 3-kinase cascade; phosphatidylinositol 3-kinase signal transduction; phosphoinositide 3-kinase cascade; PI 3-kinase cascade; PI3K cascade; PI3K signal transduction; PI3K signaling
Comment: This term was obsoleted because it represents the same signal transduction cassette as phosphatidylinositol 3-kinase signaling/protein kinase B signal transductiong ; GO:0043491.
obsolete regulation of phosphatidylinositol 3-kinase signaling (GO:0014066)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms: regulation of phosphatidylinositol 3-kinase cascade; regulation of phosphoinositide 3-kinase cascade; regulation of PI 3-kinase cascade; regulation of PI3K cascade
Comment: This term was obsoleted because it represents the same signal transduction cassette as regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction ; GO:0051896.
obsolete negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms: down regulation of phosphatidylinositol 3-kinase cascade; down-regulation of phosphatidylinositol 3-kinase cascade; downregulation of phosphatidylinositol 3-kinase cascade; inhibition of phosphatidylinositol 3-kinase cascade; negative regulation of phosphatidylinositol 3-kinase cascade; negative regulation of phosphoinositide 3-kinase cascade; negative regulation of PI 3-kinase cascade; negative regulation of PI3K cascade
Comment: This term was obsoleted because it represents the same signal transduction cassette as negative regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction ; GO:0051898.
obsolete positive regulation of phosphatidylinositol 3-kinase signaling (GO:0014068)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
Synonyms: activation of phosphoinositide 3-kinase cascade; positive regulation of phosphatidylinositol 3-kinase cascade; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of PI 3-kinase cascade; positive regulation of PI3K cascade; stimulation of phosphatidylinositol 3-kinase cascade; up regulation of phosphatidylinositol 3-kinase cascade; up-regulation of phosphatidylinositol 3-kinase cascade; upregulation of phosphatidylinositol 3-kinase cascade
Comment: This term was obsoleted because it represents the same signal transduction cassette as positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction ; GO:0051897.
postsynaptic density (GO:0014069)
Namespace: cellular_component
Definition: An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
Synonyms: neuronal postsynaptic density; post synaptic density; post-synaptic density; postsynaptic density of dendrite
response to cycloalkane (GO:0014071)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.
response to tropane (GO:0014073)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.
response to purine-containing compound (GO:0014074)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
Synonyms: response to purine
response to amine (GO:0014075)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
Synonyms: response to amine stimulus
response to fluoxetine (GO:0014076)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
Synonyms: response to selective serotonin reuptake inhibitor; response to SSRI
Comment: Note that this term is in the subset of terms that should not be used for direct manual annotation of gene products. Direct annotations to this term may be amended during annotation QC.
junctional sarcoplasmic reticulum membrane (GO:0014701)
Namespace: cellular_component
Definition: The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.
free sarcoplasmic reticulum membrane (GO:0014702)
Namespace: cellular_component
Definition: The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.
intercalated disc (GO:0014704)
Namespace: cellular_component
Definition: A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
Synonyms: intercalated disk
branchiomeric skeletal muscle development (GO:0014707)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.
regulation of somitomeric trunk muscle development (GO:0014708)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.
negative regulation of somitomeric trunk muscle development (GO:0014710)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
regulation of branchiomeric skeletal muscle development (GO:0014711)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
positive regulation of branchiomeric skeletal muscle development (GO:0014712)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
negative regulation of branchiomeric skeletal muscle development (GO:0014713)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
myoblast fate commitment in head (GO:0014714)
Namespace: biological_process
Definition: The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast fate commitment in trunk (GO:0014715)
Namespace: biological_process
Definition: The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
obsolete skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration (GO:0014716)
Namespace: biological_process
Definition: OBSOLETE. Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt.
Synonyms: satellite cell asymmetric division involved in skeletal muscle regeneration
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014717)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
positive regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014718)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.