LiteFold/GO huggingface dataset:
S-adenosylmethionine catabolic process (GO:0050843)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
Synonyms: S-adenosyl methionine catabolic process; S-adenosyl methionine catabolism; S-adenosylmethionine breakdown; S-adenosylmethionine catabolism; S-adenosylmethionine degradation; SAM catabolic process
peptidyl-selenocysteine modification (GO:0050844)
Namespace: biological_process
Definition: The modification of peptidyl-selenocysteine.
obsolete teichuronic acid metabolic process (GO:0050846)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.
Synonyms: teichuronic acid metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
progesterone receptor signaling pathway (GO:0050847)
Namespace: biological_process
Definition: A nuclear receptor-mediated signaling pathway initiated by a progesterone binding to an intracellular receptor of the nuclear receptor protein family, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms: intracellular progesterone receptor signaling pathway; nuclear receptor-mediated progesterone signaling pathway; progesterone receptor signalling pathway
regulation of calcium-mediated signaling (GO:0050848)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
Synonyms: regulation of calcium-mediated signalling
negative regulation of calcium-mediated signaling (GO:0050849)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
Synonyms: down regulation of calcium-mediated signaling; down-regulation of calcium-mediated signaling; downregulation of calcium-mediated signaling; inhibition of calcium-mediated signaling; negative regulation of calcium-mediated signalling
positive regulation of calcium-mediated signaling (GO:0050850)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.
Synonyms: activation of calcium-mediated signaling; positive regulation of calcium-mediated signalling; stimulation of calcium-mediated signaling; up regulation of calcium-mediated signaling; up-regulation of calcium-mediated signaling; upregulation of calcium-mediated signaling
antigen receptor-mediated signaling pathway (GO:0050851)
Namespace: biological_process
Definition: The series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.
Synonyms: antigen receptor-mediated signalling pathway
T cell receptor signaling pathway (GO:0050852)
Namespace: biological_process
Definition: The series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms: T lymphocyte receptor signaling pathway; T lymphocyte receptor signalling pathway; T-cell receptor signaling pathway; T-cell receptor signalling pathway; T-lymphocyte receptor signaling pathway; T-lymphocyte receptor signalling pathway; TCR signaling pathway
B cell receptor signaling pathway (GO:0050853)
Namespace: biological_process
Definition: The series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms: B cell receptor signalling pathway; B lymphocyte receptor signaling pathway; B lymphocyte receptor signalling pathway; B-cell receptor signaling pathway; B-cell receptor signalling pathway; B-lymphocyte receptor signaling pathway; B-lymphocyte receptor signalling pathway
regulation of antigen receptor-mediated signaling pathway (GO:0050854)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms: regulation of antigen receptor mediated signalling pathway
regulation of B cell receptor signaling pathway (GO:0050855)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms: regulation of B cell receptor signalling pathway; regulation of B lymphocyte receptor signaling pathway; regulation of B lymphocyte receptor signalling pathway; regulation of B-cell receptor signaling pathway; regulation of B-cell receptor signalling pathway; regulation of B-lymphocyte receptor signaling pathway; regulation of B-lymphocyte receptor signalling pathway
regulation of T cell receptor signaling pathway (GO:0050856)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms: regulation of T lymphocyte receptor signaling pathway; regulation of T lymphocyte receptor signalling pathway; regulation of T-cell receptor signaling pathway; regulation of T-cell receptor signalling pathway; regulation of T-lymphocyte receptor signaling pathway; regulation of T-lymphocyte receptor signalling pathway; regulation of TCR signaling pathway
positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms: activation of antigen receptor-mediated signaling pathway; positive regulation of antigen receptor mediated signalling pathway; stimulation of antigen receptor-mediated signaling pathway; up regulation of antigen receptor-mediated signaling pathway; up-regulation of antigen receptor-mediated signaling pathway; upregulation of antigen receptor-mediated signaling pathway
negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
Synonyms: down regulation of antigen receptor-mediated signaling pathway; down-regulation of antigen receptor-mediated signaling pathway; downregulation of antigen receptor-mediated signaling pathway; inhibition of antigen receptor-mediated signaling pathway; negative regulation of antigen receptor mediated signalling pathway
negative regulation of B cell receptor signaling pathway (GO:0050859)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms: down regulation of B cell receptor signaling pathway; down-regulation of B cell receptor signaling pathway; downregulation of B cell receptor signaling pathway; inhibition of B cell receptor signaling pathway; negative regulation of B cell receptor signalling pathway; negative regulation of B lymphocyte receptor signaling pathway; negative regulation of B lymphocyte receptor signalling pathway; negative regulation of B-cell receptor signaling pathway; negative regulation of B-cell receptor signalling pathway; negative regulation of B-lymphocyte receptor signaling pathway; negative regulation of B-lymphocyte receptor signalling pathway
negative regulation of T cell receptor signaling pathway (GO:0050860)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms: down regulation of T cell receptor signaling pathway; down-regulation of T cell receptor signaling pathway; downregulation of T cell receptor signaling pathway; inhibition of T cell receptor signaling pathway; negative regulation of T cell receptor signalling pathway; negative regulation of T lymphocyte receptor signaling pathway; negative regulation of T lymphocyte receptor signalling pathway; negative regulation of T-cell receptor signaling pathway; negative regulation of T-lymphocyte receptor signaling pathway; negative regulation of T-lymphocyte receptor signalling pathway; negative regulation of TCR signaling pathway
positive regulation of B cell receptor signaling pathway (GO:0050861)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
Synonyms: activation of B cell receptor signaling pathway; positive regulation of B cell receptor signalling pathway; positive regulation of B lymphocyte receptor signaling pathway; positive regulation of B lymphocyte receptor signalling pathway; positive regulation of B-cell receptor signaling pathway; positive regulation of B-cell receptor signalling pathway; positive regulation of B-lymphocyte receptor signaling pathway; positive regulation of B-lymphocyte receptor signalling pathway; stimulation of B cell receptor signaling pathway; up regulation of B cell receptor signaling pathway; up-regulation of B cell receptor signaling pathway; upregulation of B cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway (GO:0050862)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
Synonyms: activation of T cell receptor signaling pathway; positive regulation of T cell receptor signalling pathway; positive regulation of T lymphocyte receptor signaling pathway; positive regulation of T lymphocyte receptor signalling pathway; positive regulation of T-cell receptor signaling pathway; positive regulation of T-lymphocyte receptor signaling pathway; positive regulation of T-lymphocyte receptor signalling pathway; positive regulation of TCR signaling pathway; stimulation of T cell receptor signaling pathway; up regulation of T cell receptor signaling pathway; up-regulation of T cell receptor signaling pathway; upregulation of T cell receptor signaling pathway
regulation of T cell activation (GO:0050863)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of T cell activation.
Synonyms: regulation of T lymphocyte activation; regulation of T-cell activation; regulation of T-lymphocyte activation
regulation of B cell activation (GO:0050864)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of B cell activation.
Synonyms: regulation of B lymphocyte activation; regulation of B-cell activation; regulation of B-lymphocyte activation
regulation of cell activation (GO:0050865)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
negative regulation of cell activation (GO:0050866)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
Synonyms: down regulation of cell activation; down-regulation of cell activation; downregulation of cell activation; inhibition of cell activation
positive regulation of cell activation (GO:0050867)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of activation.
Synonyms: activation of cell activation; stimulation of cell activation; up regulation of cell activation; up-regulation of cell activation; upregulation of cell activation
negative regulation of B cell activation (GO:0050869)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
Synonyms: down regulation of B cell activation; down-regulation of B cell activation; downregulation of B cell activation; inhibition of B cell activation; negative regulation of B lymphocyte activation; negative regulation of B-cell activation; negative regulation of B-lymphocyte activation
positive regulation of T cell activation (GO:0050870)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of T cell activation.
Synonyms: activation of T cell activation; positive regulation of T lymphocyte activation; positive regulation of T-cell activation; positive regulation of T-lymphocyte activation; stimulation of T cell activation; up regulation of T cell activation; up-regulation of T cell activation; upregulation of T cell activation
positive regulation of B cell activation (GO:0050871)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of B cell activation.
Synonyms: activation of B cell activation; positive regulation of B lymphocyte activation; positive regulation of B-cell activation; positive regulation of B-lymphocyte activation; stimulation of B cell activation; up regulation of B cell activation; up-regulation of B cell activation; upregulation of B cell activation
white fat cell differentiation (GO:0050872)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
Synonyms: white adipocyte cell differentiation; white adipocyte differentiation
brown fat cell differentiation (GO:0050873)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
Synonyms: brown adipocyte cell differentiation; brown adipocyte differentiation
nervous system process (GO:0050877)
Namespace: biological_process
Definition: An organ system process carried out by any of the organs or tissues of the neurological system.
Synonyms: neurological system process; neurophysiological process; pan-neural process
musculoskeletal movement (GO:0050881)
Namespace: biological_process
Definition: The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.
musculoskeletal movement, spinal reflex action (GO:0050883)
Namespace: biological_process
Definition: Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.
neuromuscular process controlling posture (GO:0050884)
Namespace: biological_process
Definition: Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
Synonyms: regulation of posture
neuromuscular process controlling balance (GO:0050885)
Namespace: biological_process
Definition: Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
Synonyms: regulation of balance
determination of stimulus location (GO:0050888)
Namespace: biological_process
Definition: The determination of where on the body surface, within the body or in the environment a stimulus originates.
determination of stimulus intensity (GO:0050889)
Namespace: biological_process
Definition: The determination of the perceived strength of a sensory stimulus.
cognition (GO:0050890)
Namespace: biological_process
Definition: The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
multicellular organismal-level water homeostasis (GO:0050891)
Namespace: biological_process
Definition: A chemical homeostatic process involved in the maintenance of a steady state level of water within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms: body fluid osmoregulation; multicellular organismal water homeostasis
intestinal absorption (GO:0050892)
Namespace: biological_process
Definition: A process in which nutrients are taken up from the contents of the intestine.
sensory processing (GO:0050893)
Namespace: biological_process
Definition: Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.
determination of affect (GO:0050894)
Namespace: biological_process
Definition: Any process in which an emotional response is associated with a particular sensory stimulation.
response to stimulus (GO:0050896)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
Synonyms: physiological response to stimulus
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
cobalt ion binding (GO:0050897)
Namespace: molecular_function
Definition: Binding to a cobalt ion (Co2+).
Synonyms: Co ion binding; cobalt binding
nitrile metabolic process (GO:0050898)
Namespace: biological_process
Definition: The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.
Synonyms: nitrile metabolism
leukocyte migration (GO:0050900)
Namespace: biological_process
Definition: The movement of a leukocyte within or between different tissues and organs of the body.
Synonyms: immune cell migration; immune cell trafficking; leucocyte migration; leucocyte trafficking; leukocyte trafficking
leukocyte tethering or rolling (GO:0050901)
Namespace: biological_process
Definition: Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).
leukocyte adhesive activation (GO:0050902)
Namespace: biological_process
Definition: The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.
Synonyms: leukocyte adhesive triggering
leukocyte activation-dependent arrest (GO:0050903)
Namespace: biological_process
Definition: The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.
diapedesis (GO:0050904)
Namespace: biological_process
Definition: The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
Comment: Note that the term diapedesis, although sometimes used as a direct synonym for cellular extravasation, is used here for the specific final step of the process, in concordance with recent reviews of the topic.
neuromuscular process (GO:0050905)
Namespace: biological_process
Definition: Any process pertaining to the functions of the nervous and muscular systems of an organism.
Synonyms: neuromotor process; neuromuscular physiological process
detection of stimulus involved in sensory perception (GO:0050906)
Namespace: biological_process
Definition: The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.
Synonyms: sensory detection of stimulus; sensory perception, sensory transduction of stimulus; sensory perception, stimulus detection; sensory transduction
detection of chemical stimulus involved in sensory perception (GO:0050907)
Namespace: biological_process
Definition: The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.
Synonyms: sensory detection of chemical stimulus; sensory detection of chemical stimulus during sensory perception; sensory perception, sensory detection of chemical stimulus; sensory perception, sensory transduction of chemical stimulus; sensory transduction of chemical stimulus; sensory transduction of chemical stimulus during sensory perception
detection of light stimulus involved in visual perception (GO:0050908)
Namespace: biological_process
Definition: The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
Synonyms: sensory detection of light during visual perception; sensory detection of light stimulus during visual perception; sensory transduction of light during visual perception; sensory transduction of light stimulus during visual perception; visual perception, detection of light stimulus; visual perception, sensory transduction during perception of light; visual perception, sensory transduction of light stimulus
sensory perception of taste (GO:0050909)
Namespace: biological_process
Definition: The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
Synonyms: gustation; sense of taste; taste; taste perception
detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)
Namespace: biological_process
Definition: The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.
Synonyms: detection of sound; hearing, sensory transduction of sound; perception of sound, detection of mechanical stimulus; perception of sound, sensory detection of mechanical stimulus; perception of sound, sensory transduction of mechanical stimulus; sensory detection of mechanical stimulus during perception of sound; sensory transduction of mechanical stimulus during perception of sound; sensory transduction of sound