LiteFold/GO huggingface dataset:
obsolete regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0072335)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation; regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation; regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0072336)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: negative regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; negative regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation; negative regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation; negative regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation
Comment: This term was obsoleted because it represents a GO-CAM model.
modified amino acid transport (GO:0072337)
Namespace: biological_process
Definition: The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: amino acid derivative transport
lactam metabolic process (GO:0072338)
Namespace: biological_process
Definition: The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
Synonyms: cellular lactam metabolic process; cellular lactam metabolism
lactam biosynthetic process (GO:0072339)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
Synonyms: cellular lactam anabolism; cellular lactam biosynthesis; cellular lactam biosynthetic process; cellular lactam formation; cellular lactam synthesis
lactam catabolic process (GO:0072340)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
Synonyms: cellular lactam breakdown; cellular lactam catabolic process; cellular lactam catabolism; cellular lactam degradation
modified amino acid binding (GO:0072341)
Namespace: molecular_function
Definition: Binding to a modified amino acid.
Synonyms: amino acid derivative binding
response to anion stress (GO:0072342)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.
pancreatic stellate cell proliferation (GO:0072343)
Namespace: biological_process
Definition: The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.
rescue of stalled cytosolic ribosome (GO:0072344)
Namespace: biological_process
Definition: A process of cytosolic translational elongation that takes place when a cytosolic ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.
NAADP-sensitive calcium-release channel activity (GO:0072345)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.
cADPR-sensitive calcium-release channel activity (GO:0072346)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.
response to anesthetic (GO:0072347)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
Synonyms: response to anaesthetic
sulfur compound transport (GO:0072348)
Namespace: biological_process
Definition: The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: sulfur-containing compound transport
modified amino acid transmembrane transporter activity (GO:0072349)
Namespace: molecular_function
Definition: Enables the transfer of modified amino acids from one side of a membrane to the other.
Synonyms: amino acid derivative transmembrane transporter activity; modified amino acid transporter activity
tricarboxylic acid metabolic process (GO:0072350)
Namespace: biological_process
Definition: The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).
Synonyms: tricarboxylic acid metabolism
tricarboxylic acid biosynthetic process (GO:0072351)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
Synonyms: tricarboxylate biosynthesis; tricarboxylate biosynthetic process; tricarboxylic acid anabolism; tricarboxylic acid biosynthesis; tricarboxylic acid formation; tricarboxylic acid synthesis
tricarboxylic acid catabolic process (GO:0072352)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
Synonyms: tricarboxylate catabolic process; tricarboxylate catabolism; tricarboxylic acid breakdown; tricarboxylic acid catabolism; tricarboxylic acid degradation
obsolete cellular age-dependent response to reactive oxygen species (GO:0072353)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
Comment: This term was obsoleted because it represents a phenotype.
histone H3T3 kinase activity (GO:0072354)
Namespace: molecular_function
Definition: Catalysis of the reaction: histone H3-threonine (position 3) + ATP = histone H3-phosphothreonine (position 3) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 3 of histone H3.
Synonyms: histone H3-T3 kinase activity; histone kinase activity (H3-T3 specific); histone threonine kinase activity (H3-T3 specific); histone-threonine kinase activity (H3-T3 specific)
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
obsolete histone H3-T3 phosphorylation (GO:0072355)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone.
Comment: This term was obsoleted because it represents a molecular function.
chromosome passenger complex localization to kinetochore (GO:0072356)
Namespace: biological_process
Definition: A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.
Synonyms: chromosomal passenger complex localization to kinetochore; chromosome passenger complex localisation to kinetochore; CPC complex localization to kinetochore; CPC localization to kinetochore
PTW/PP1 phosphatase complex (GO:0072357)
Namespace: cellular_component
Definition: A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
circulatory system development (GO:0072359)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
Synonyms: cardiovascular system development
vascular cord development (GO:0072360)
Namespace: biological_process
Definition: The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.
obsolete regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter (GO:0072361)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter (GO:0072362)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of glycolysis by negative regulation of transcription from an RNA polymerase II promoter
Comment: The reason for obsoletion is that this term represented a GO-CAM model.
obsolete regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter (GO:0072363)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of glycolysis by positive regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter (GO:0072364)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of cellular ketone metabolic process by regulation of transcription from an RNA polymerase II promoter; regulation of cellular ketone metabolism by regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter (GO:0072365)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter; regulation of cellular ketone metabolism by negative regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter (GO:0072366)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of cellular ketone metabolic process by positive regulation of transcription from an RNA polymerase II promoter; regulation of cellular ketone metabolism by positive regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter (GO:0072368)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of lipid transport by negative regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter (GO:0072369)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: regulation of lipid transport by positive regulation of transcription from an RNA polymerase II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete histone H2A-S121 phosphorylation (GO:0072370)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone.
Synonyms: histone H2A phosphorylation at S121; histone H2AS121 phosphorylation
Comment: This term was obsoleted because it represents a molecular function.
histone H2AS121 kinase activity (GO:0072371)
Namespace: molecular_function
Definition: Catalysis of the reaction: histone H2A-serine (position 121) + ATP = histone H2A-phosphoserine (position 121) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 121 of histone H2A. This serine residue is present inthe histone H2A of fungi and Tetrahymena. This position corresponds to T120 in metazoa.
Synonyms: histone H2A-S121 kinase activity; histone kinase activity (H2A-S121 specific); histone serine kinase activity (H2A-S121 specific); histone-serine kinase activity (H2A-S121 specific)
obsolete alpha-carotene epsilon hydroxylase activity (GO:0072373)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.
Comment: This term was obsoleted because it represents a specific substrate of carotene epsilon hydroxylase activity ; GO:0072374
carotene epsilon hydroxylase activity (GO:0072374)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]. Zeinoxanthin may also be used as the substrate, in which case lutein is produced.
medium-term memory (GO:0072375)
Namespace: biological_process
Definition: The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
Synonyms: middle-term memory; MTM
protein activation cascade (GO:0072376)
Namespace: biological_process
Definition: A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.
Synonyms: protein activation pathway; protein activitory cascade
blood coagulation, common pathway (GO:0072377)
Namespace: biological_process
Definition: A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated Factor Xa by either the intrinsic or extrinsic pathway, to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.
Comment: See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.
blood coagulation, fibrin clot formation (GO:0072378)
Namespace: biological_process
Definition: A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
Comment: See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.
ER membrane insertion complex (GO:0072379)
Namespace: cellular_component
Definition: A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.
Synonyms: endoplasmic reticulum membrane insertion complex
TRC complex (GO:0072380)
Namespace: cellular_component
Definition: A protein complex found in yeast that contains GET4, MDY2 (GET5), SGT2, and at least two heat shock proteins, HSP104 and YBR137W. The TRC complex transfers tail-anchored (TA) proteins to GET3 for targeting to the endoplasmic reticulum membrane.
Synonyms: GET4-GET5 transmembrane domain recognition complex; TMD recognition complex
obsolete positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation (GO:0072381)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Synonyms: positive regulation of canonical Wnt receptor signaling pathway involved in neural crest cell differentiation; positive regulation of canonical Wnt receptor signalling pathway involved in neural crest cell differentiation; positive regulation of canonical Wnt-activated signaling pathway involved in neural crest cell differentiation; positive regulation of Wnt receptor signaling pathway through beta-catenin involved in neural crest cell differentiation
Comment: This term was obsoleted because it represents a GO-CAM model.
minus-end-directed vesicle transport along microtubule (GO:0072382)
Namespace: biological_process
Definition: The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
Synonyms: microtubule minus-end-directed vesicle distribution; microtubule minus-end-directed vesicle localization
plus-end-directed vesicle transport along microtubule (GO:0072383)
Namespace: biological_process
Definition: The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
Synonyms: microtubule plus-end-directed vesicle distribution; microtubule plus-end-directed vesicle localization
organelle transport along microtubule (GO:0072384)
Namespace: biological_process
Definition: The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
Synonyms: microtubule-based organelle localization
minus-end-directed organelle transport along microtubule (GO:0072385)
Namespace: biological_process
Definition: The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
Synonyms: microtubule minus-end-directed organelle distribution; microtubule minus-end-directed organelle localization
plus-end-directed organelle transport along microtubule (GO:0072386)
Namespace: biological_process
Definition: The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
Synonyms: microtubule plus-end-directed organelle distribution; microtubule plus-end-directed organelle localization
flavin adenine dinucleotide metabolic process (GO:0072387)
Namespace: biological_process
Definition: The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
Synonyms: FAD or FADH2 metabolic process; flavin adenine dinucleotide metabolism; flavin-adenine dinucleotide metabolic process