LiteFold/GO huggingface dataset:
regulation of circulating fibrinogen levels (GO:0044537)
Namespace: biological_process
Definition: Any process that modulates the quantity of fibrinogen circulating in the bloodstream.
host cell periphery (GO:0044538)
Namespace: cellular_component
Definition: The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.
long-chain fatty acid import into cell (GO:0044539)
Namespace: biological_process
Definition: The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: long-chain fatty acid import; long-chain fatty acid uptake
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
L-cystine L-cysteine-lyase (deaminating) activity (GO:0044540)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-cystine + H2O = S-sulfanyl-L-cysteine + pyruvate + NH4+.
obsolete zymogen activation in another organism (GO:0044541)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.
Synonyms: zymogen activation in other organism
Comment: This term was obsoleted because it is too general.
symbiont-mediated activation of host plasminogen (GO:0044542)
Namespace: biological_process
Definition: A process in which a symbiont initiates, promotes, or enhances the normal activation of plasminogen, the pathway resulting in the processing of inactive plasminogen to active plasmin in the host organism. This can facilitate the dissemination of the symbiont into host tissues. It can also be used to destroy complement, opsonins as well as antibacterial proteins like histones.
Synonyms: plasminogen activation in another organism; plasminogen activation in other organism
obsolete envenomation resulting in zymogen activation in another organism (GO:0044543)
Namespace: biological_process
Definition: OBSOLETE. The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form.
Synonyms: envenomation resulting in zymogen activation in other organism
Comment: This term was obsoleted because it represents a molecular function.
venom-mediated plasminogen activation (GO:0044544)
Namespace: biological_process
Definition: A process in which an organism initiates, promotes, or enhances the activation of plasminogen into plasmin in another organism via the action of a venom. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
Synonyms: envenomation resulting in plasminogen activation in another organism; envenomation resulting in plasminogen activation in other organism
NSL complex (GO:0044545)
Namespace: cellular_component
Definition: A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.
Synonyms: non-specific lethal complex
NLRP3 inflammasome complex assembly (GO:0044546)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.
Synonyms: NALP3 inflammasome complex assembly; NLRP3 inflammasome activation
DNA topoisomerase binding (GO:0044547)
Namespace: molecular_function
Definition: Binding to a DNA topoisomerase.
Synonyms: DNA topoisomerase I binding
GTP cyclohydrolase binding (GO:0044549)
Namespace: molecular_function
Definition: Binding to a GTP cyclohydrolase.
Synonyms: GTP cyclohydrolase I binding
secondary metabolite biosynthetic process (GO:0044550)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
Synonyms: secondary metabolite biosynthesis
venom-mediated vasodilation (GO:0044551)
Namespace: biological_process
Definition: A process in which an organism initiates, promotes, or enhances the widening of blood vessels by small muscles in their walls in another organism via the action of a venom, concomittantly reducing blood pressure in the bitten/stung organism.
Synonyms: envenomation resulting in modulation of vasodilation in other organism; envenomation resulting in regulation of vasodilation in other organism; envenomation resulting in vasodilation in another organism; envenomation resulting in vasodilation in other organism; venom-mediated vasorelaxation
obsolete symbiont-mediated vasodilation in host (GO:0044552)
Namespace: biological_process
Definition: OBSOLETE. A process in which a symbiont causes vasodilation of blood vessels in its host organism, usually causing a reduction in blood pressure. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: modulation of vasodilation in other organism; regulation of vasodilation in other organism; vasodilation in other organism
Comment: This term was obsoleted because it is too general.
obsolete modulation of biological quality in another organism (GO:0044553)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
Synonyms: modulation of biological quality in other organism; regulation of biological quality in other organism
Comment: This term was obsoleted because it is too general.
obsolete modulation of heart rate in another organism (GO:0044554)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency or rate of heart contraction of another organism.
Synonyms: modulation of heart rate in other organism; regulation of heart rate in other organism
Comment: This term was obsoleted because it is too general.
obsolete negative regulation of heart rate in another organism (GO:0044555)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency of heart contraction of another organism.
Synonyms: negative regulation of heart rate in other organism
Comment: This term was obsoleted because it is too general.
venom-mediated reduction of heart rate (GO:0044556)
Namespace: biological_process
Definition: A process in which an organism slows down the heart rate in another organism via the action of a venom.
Synonyms: envenomation reducing heart rate; envenomation resulting in negative regulation of heart rate in another organism; envenomation resulting in negative regulation of heart rate of other organism; venom-mediated bradycardia; venom-mediated heart rate lowering
relaxation of smooth muscle (GO:0044557)
Namespace: biological_process
Definition: A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
Synonyms: smooth muscle relaxation
uterine smooth muscle relaxation (GO:0044558)
Namespace: biological_process
Definition: A process in which the extent of smooth muscle contraction is reduced in the uterus.
Synonyms: smooth muscle relaxation of the uterus
venom-mediated perturbation of voltage-gated potassium channel activity (GO:0044559)
Namespace: biological_process
Definition: A process in which an organism alters or subverts the activity of a voltage-gated potassium channel in another organism via the action of a venom.
Synonyms: envenomation resulting in modulation of voltage-gated potassium channel activity in another organism; envenomation resulting in modulation of voltage-gated potassium channel activity in other organism
obsolete modulation of ion channel activity in another organism (GO:0044561)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism.
Synonyms: modulation of ion channel activity in other organism; regulation of ion channel activity in other organism
Comment: This term was obsoleted because it is too general.
venom-mediated inhibition of voltage-gated potassium channel activity (GO:0044562)
Namespace: biological_process
Definition: A process in which an organism inhibits or disrupts the activity of a  voltage-gated potassium channel in another organism via the action of a venom.
Synonyms: envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism; envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism
obsolete envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel (GO:0044563)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.
Synonyms: envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism; voltage-dependence of activation shift (to the left)
Comment: This term was obsoleted because it represents a substep of the inhibited activity and is outside the scope of GO.
obsolete envenomation resulting in occlusion of the pore of voltage-gated potassium channel (GO:0044564)
Namespace: biological_process
Definition: OBSOLETE. A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism.
Synonyms: envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism
Comment: This term was obsoleted because it represents a substep of the inhibited activity and is outside the scope of GO.
dendritic cell proliferation (GO:0044565)
Namespace: biological_process
Definition: The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
chondrocyte activation (GO:0044566)
Namespace: biological_process
Definition: A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.
primary cell wall cellulose synthase complex (GO:0044567)
Namespace: cellular_component
Definition: A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.
Synonyms: primary cell wall CESA complex; primary cell-wall cellulose synthase complex
secondary cell wall cellulose synthase complex (GO:0044568)
Namespace: cellular_component
Definition: A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.
Synonyms: secondary cell wall CESA complex; secondary cell-wall cellulose synthase complex
[Ni-Fe] hydrogenase complex (GO:0044569)
Namespace: cellular_component
Definition: A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.
Synonyms: Ni-Fe hydrogenase complex; nickel-iron hydrogenase complex
starch utilization system complex (GO:0044570)
Namespace: cellular_component
Definition: A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.
Synonyms: Sus complex
[4Fe-4S] cluster assembly (GO:0044572)
Namespace: biological_process
Definition: The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
Synonyms: 4Fe-4S cluster assembly; [4Fe-4S] cluster biosynthetic process
nitrogenase P cluster assembly (GO:0044573)
Namespace: biological_process
Definition: The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.
Synonyms: nitrogenase P cluster biosynthesis; nitrogenase P cluster maturation
starch utilization system complex assembly (GO:0044574)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.
Synonyms: assembly of starch utilization system complex; SUS complex assembly
cellulosome assembly (GO:0044575)
Namespace: biological_process
Definition: The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.
obsolete pentose catabolic process to ethanol (GO:0044576)
Namespace: biological_process
Definition: OBSOLETE. The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.
Synonyms: pentose catabolism to ethanol
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
D-xylose fermentation (GO:0044577)
Namespace: biological_process
Definition: The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, into ethanol.
Synonyms: D-xylose catabolic process to ethanol; xylose catabolism to ethanol
butyryl-CoA biosynthetic process (GO:0044578)
Namespace: biological_process
Definition: The chemical reactions and pathway resulting in the formation of butyryl-CoA.
Synonyms: butyryl-CoA biosynthesis
butyryl-CoA biosynthetic process from acetyl-CoA (GO:0044579)
Namespace: biological_process
Definition: The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.
Synonyms: butyryl-CoA biosynthesis from acetyl-CoA
butyryl-CoA catabolic process (GO:0044580)
Namespace: biological_process
Definition: The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.
Synonyms: butyryl-CoA catabolism
butyryl-CoA catabolic process to butanol (GO:0044582)
Namespace: biological_process
Definition: The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.
Synonyms: butyryl-CoA catabolism to butanol
cellotriose binding (GO:0044583)
Namespace: molecular_function
Definition: Binding to cellotriose.
cellodextrin binding (GO:0044584)
Namespace: molecular_function
Definition: Binding to a cellodextrin, a glucose polymer of 2 or more glucose monomers.
cellobiose binding (GO:0044585)
Namespace: molecular_function
Definition: Binding to cellobiose, a disaccharide that represents the basic repeating unit of cellulose.
cellotetraose binding (GO:0044586)
Namespace: molecular_function
Definition: Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
cellopentaose binding (GO:0044587)
Namespace: molecular_function
Definition: Binding to a cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
laminaribiose binding (GO:0044588)
Namespace: molecular_function
Definition: Binding to laminaribiose, a disaccharide.
iron-sulfur-molybdenum cofactor binding (GO:0044590)
Namespace: molecular_function
Definition: Binding to iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
Synonyms: FeMo co binding; FeMoco binding
response to amylopectin (GO:0044591)
Namespace: biological_process
Definition: A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.
response to pullulan (GO:0044592)
Namespace: biological_process
Definition: A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.
iron-sulfur-molybdenum cofactor assembly (GO:0044593)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
Synonyms: FeMoco assembly; FeMoco biosynthetic process; iron molybdenum cofactor assembly; iron molybdenum cofactor biosynthesis; iron molybdenum cofactor biosynthetic process
obsolete decaprenyldihydroxybenzoate methyltransferase activity (GO:0044595)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.
Comment: This term was obsoleted because it represents a specific substrate of 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity ; GO:0010420
obsolete 3-demethylubiquinol-10 3-O-methyltransferase activity (GO:0044596)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-10 = S-adenosyl-L-homocysteine + ubiquinol-10.
Comment: This term was obsoleted because it represents a specific substrate of 3-demethylubiquinol-n 3-O-methyltransferase activity ; GO:0061542.
daunorubicin metabolic process (GO:0044597)
Namespace: biological_process
Definition: The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.
doxorubicin metabolic process (GO:0044598)
Namespace: biological_process
Definition: The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.
protein guanylyltransferase activity (GO:0044600)
Namespace: molecular_function
Definition: Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.
protein denucleotidylation (GO:0044601)
Namespace: biological_process
Definition: The removal of a nucleotide from a protein amino acid.
protein deadenylylation (GO:0044602)
Namespace: biological_process
Definition: The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.
Synonyms: protein deAMPylation
protein adenylylhydrolase activity (GO:0044603)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.
Synonyms: protein deAMPylase activity; protein deAMPylation activity
ABC-type phytochelatin transporter activity (GO:0044604)
Namespace: molecular_function
Definition: Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
Synonyms: ABC-type phytochelatin transmembrane transporter activity; ATP-dependent phytochelatin transmembrane transporter activity; ATPase-coupled phytochelatin transmembrane transporter activity; cadystin transmembrane transporter activity; cadystin transmembrane transporter ATPase activity; cadystin transporter activity; phytochelatin transmembrane transporter activity; phytochelatin transmembrane transporter ATPase activity; phytochelatin transporter activity
phosphocholine transferase activity (GO:0044605)
Namespace: molecular_function
Definition: Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.
phosphocholine hydrolase activity (GO:0044606)
Namespace: molecular_function
Definition: Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.
obsolete disruption by symbiont of host endothelial cells (GO:0044607)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism has a negative effect on the functioning of the host's endothelial cells.
Comment: This term was obsoleted because the cell type should be captured as an annotation extension.
DBIRD complex (GO:0044609)
Namespace: cellular_component
Definition: A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.
FMN transmembrane transporter activity (GO:0044610)
Namespace: molecular_function
Definition: Enables the directed movement of flavine mononucleotide (FMN) from one side of a membrane to the other.
Synonyms: flavine mononucleotide transmembrane transporter activity
nuclear pore inner ring (GO:0044611)
Namespace: cellular_component
Definition: A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.
Synonyms: Nup170 complex
nuclear pore linkers (GO:0044612)
Namespace: cellular_component
Definition: A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).
Synonyms: Nic96 complex; Nup82 complex
nuclear pore central transport channel (GO:0044613)
Namespace: cellular_component
Definition: The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
Synonyms: karyopherin docking complex; nuclear pore central channel; nuclear pore central plug; nuclear pore transport channel