LiteFold/GO huggingface dataset:
basolateral cytoplasm (GO:0090652)
Namespace: cellular_component
Definition: The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.
apical recycling endosome (GO:0090653)
Namespace: cellular_component
Definition: Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.
basolateral recycling endosome (GO:0090654)
Namespace: cellular_component
Definition: Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.
double-stranded/single-stranded junction telomeric DNA binding (GO:0090655)
Namespace: molecular_function
Definition: Binding to a junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.
t-circle formation (GO:0090656)
Namespace: biological_process
Definition: A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).
Synonyms: telomeric circle formation
telomeric loop disassembly (GO:0090657)
Namespace: biological_process
Definition: The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
Synonyms: T loop disassembly; t-loop disassembly
cone matrix sheath (GO:0090658)
Namespace: cellular_component
Definition: A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.
walking behavior (GO:0090659)
Namespace: biological_process
Definition: The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
Synonyms: locomotor gait pattern
cerebrospinal fluid circulation (GO:0090660)
Namespace: biological_process
Definition: The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.
Synonyms: cerebrospinal fluid flow; CSF circulation; CSF flow
box H/ACA telomerase RNP complex (GO:0090661)
Namespace: cellular_component
Definition: A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.
galanin-activated signaling pathway (GO:0090663)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.
Synonyms: galanin signaling pathway; galanin signalling pathway; galanin-activated signalling pathway
response to high population density (GO:0090664)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.
Synonyms: response to crowding
glycoprotein complex (GO:0090665)
Namespace: cellular_component
Definition: A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.
Comment: An example is the Dictyostelium multi protein pspB complex, which is secreted from prespore vesicles and incorporated into the spore coat.
scaRNA localization to Cajal body (GO:0090666)
Namespace: biological_process
Definition: A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
cell chemotaxis to vascular endothelial growth factor (GO:0090667)
Namespace: biological_process
Definition: The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).
endothelial cell chemotaxis to vascular endothelial growth factor (GO:0090668)
Namespace: biological_process
Definition: The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).
telomerase RNA stabilization (GO:0090669)
Namespace: biological_process
Definition: Prevention of degradation of telomerase RNA (TERC) molecules.
Synonyms: TERC stabilization
RNA localization to Cajal body (GO:0090670)
Namespace: biological_process
Definition: A process in which an RNA is transported to, or maintained in, a Cajal body.
telomerase RNA localization to Cajal body (GO:0090671)
Namespace: biological_process
Definition: A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.
endothelial cell-matrix adhesion (GO:0090673)
Namespace: biological_process
Definition: The binding of an endothelial cell to the extracellular matrix via adhesion molecules.
obsolete endothelial cell-matrix adhesion via fibronectin (GO:0090674)
Namespace: biological_process
Definition: OBSOLETE. The binding of an endothelial cell to the extracellular matrix via fibronectin.
Comment: The reason for obsoletion is that this term represents a method of annotation rather than a distinct biological process.
intermicrovillar adhesion (GO:0090675)
Namespace: biological_process
Definition: The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.
calcium ion transmembrane transport via low voltage-gated calcium channel (GO:0090676)
Namespace: biological_process
Definition: A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.
Synonyms: generation of T-type calcium current
reversible differentiation (GO:0090677)
Namespace: biological_process
Definition: A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.
cell dedifferentiation involved in phenotypic switching (GO:0090678)
Namespace: biological_process
Definition: A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
cell differentiation involved in phenotypic switching (GO:0090679)
Namespace: biological_process
Definition: A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
viral release via disruption of host outer membrane (GO:0090680)
Namespace: biological_process
Definition: The dissemination of mature viral particles from a host cell via the destabilization of the cell outer membrane.
Synonyms: disruption by virus of host outer membrane
GPCR bitter taste receptor activity (GO:0090682)
Namespace: molecular_function
Definition: A G protein-coupled receptor activity that is responsible for the sense of bitter taste.
Synonyms: G protein-coupled receptor bitter taste receptor activity; G-protein coupled receptor bitter taste receptor activity
GPCR sweet taste receptor activity (GO:0090683)
Namespace: molecular_function
Definition: A G protein-coupled receptor activity that is responsible for the sense of sweet taste.
Synonyms: G-protein coupled receptor sweet taste receptor activity
contact chemoreceptor activity (GO:0090684)
Namespace: molecular_function
Definition: A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.
Synonyms: contact chemosensation receptor activity
RNA localization to nucleus (GO:0090685)
Namespace: biological_process
Definition: A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
Synonyms: RNA localisation to nucleus
glycine betaine-activated nonselective monoatomic cation channel activity (GO:0090686)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a monoatomic cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.
Synonyms: glycine betaine-activated nonselective monovalent cation channel activity
activation of meiosis I spindle assembly checkpoint (GO:0090687)
Namespace: biological_process
Definition: Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.
cleavage furrow rim (GO:0090688)
Namespace: cellular_component
Definition: The part of the cleavage furrow closest to the cell surface.
cleavage furrow leading edge (GO:0090689)
Namespace: cellular_component
Definition: The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.
obsolete heteroreceptor complex (GO:0090690)
Namespace: cellular_component
Definition: OBSOLETE. A receptor complex that consists of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger. The formation of the higher level complex initiates a change in cell function.
Comment: This term was obsoleted as it was created in error.
formation of plant organ boundary (GO:0090691)
Namespace: biological_process
Definition: The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.
mitochondrial membrane scission site (GO:0090692)
Namespace: cellular_component
Definition: The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.
plant organ senescence (GO:0090693)
Namespace: biological_process
Definition: A plant organ developmental process during which a plant dismantles cellular components to reclaim the cellular building blocks and nutrients that have been deposited in the plant organs during growth.
Scc2-Scc4 cohesin loading complex (GO:0090694)
Namespace: cellular_component
Definition: A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.
Synonyms: Mis4-Ssl3 cohesin loading complex
Wpl/Pds5 cohesin loading/unloading complex (GO:0090695)
Namespace: cellular_component
Definition: A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.
post-embryonic plant organ development (GO:0090696)
Namespace: biological_process
Definition: Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
post-embryonic plant organ morphogenesis (GO:0090697)
Namespace: biological_process
Definition: Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
maintenance of plant organ identity (GO:0090700)
Namespace: biological_process
Definition: The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
specification of plant organ identity (GO:0090701)
Namespace: biological_process
Definition: The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
obsolete triplex DNA unwinding (GO:0090703)
Namespace: biological_process
Definition: OBSOLETE. The process by which a three-stranded D-loop DNA is unwound or 'melted'.
Comment: This term was made obsolete because it was created in error.
nicotinate-O-glucosyltransferase activity (GO:0090704)
Namespace: molecular_function
Definition: Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.
trichome papilla (GO:0090705)
Namespace: cellular_component
Definition: A plant cell papilla that is part of a trichome cell.
Comment: Part of trichome cell (PO:0008030).
specification of plant organ position (GO:0090706)
Namespace: biological_process
Definition: The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.
establishment of plant organ orientation (GO:0090707)
Namespace: biological_process
Definition: The process that determines the orientation of a plant organ or tissue with reference to an axis.
specification of plant organ axis polarity (GO:0090708)
Namespace: biological_process
Definition: The process in which the polarity of a plant organ axis is specified.
regulation of timing of plant organ formation (GO:0090709)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.
FMN hydrolase activity (GO:0090711)
Namespace: molecular_function
Definition: Catalysis of the reaction: FMN + H2O = phosphate + riboflavin.
Synonyms: FMN phosphatase
basal pole of outer hair cell (GO:0090712)
Namespace: cellular_component
Definition: The end of the outer hair cell which receives and transmits neural signals.
immunological memory process (GO:0090713)
Namespace: biological_process
Definition: Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.
innate immunity memory response (GO:0090714)
Namespace: biological_process
Definition: An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.
adaptive immune memory response (GO:0090716)
Namespace: biological_process
Definition: An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
adaptive immune memory response involving T cells and B cells (GO:0090717)
Namespace: biological_process
Definition: An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
adaptive immune effector response involving T cells and B lineage cells (GO:0090719)
Namespace: biological_process
Definition: An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.
primary adaptive immune response involving T cells and B cells (GO:0090721)
Namespace: biological_process
Definition: An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.
obsolete growth cone part (GO:0090723)
Namespace: cellular_component
Definition: OBSOLETE. Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite.
central region of growth cone (GO:0090724)
Namespace: cellular_component
Definition: The center of the migrating motile tip of a growing nerve cell axon or dendrite.
peripheral region of growth cone (GO:0090725)
Namespace: cellular_component
Definition: The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.
cortical dynamic polarity patch (GO:0090726)
Namespace: cellular_component
Definition: A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.
Synonyms: dynamic polarity patch at the cell cortex
positive regulation of brood size (GO:0090727)
Namespace: biological_process
Definition: Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
negative regulation of brood size (GO:0090728)
Namespace: biological_process
Definition: Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
toxin activity (GO:0090729)
Namespace: molecular_function
Definition: Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.
Synonyms: toxin receptor binding
Las1 complex (GO:0090730)
Namespace: cellular_component
Definition: A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).
Synonyms: Las1-Grc3-Rat1-Rai1
cellular response to very-low-density lipoprotein particle stimulus (GO:0090731)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very-low-density lipoprotein particle stimulus.
Synonyms: cellular response to VLDL particle stimulus
cofilin-actin rod (GO:0090732)
Namespace: cellular_component
Definition: A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and disulfide cross-linked cofilin multimers.
tenascin complex (GO:0090733)
Namespace: cellular_component
Definition: A homotrimeric or homohexameric extracellular matrix complex involved in cell adhesion and cell migration. In mammals, four complexes exist: Tenascin-C, Tenascin-N (also known as Tenascin-W), Tenascin-X and Tenascin-R.
Synonyms: Tenascin-C; Tenascin-N; Tenascin-R; Tenascin-W; Tenascin-X
DNA repair complex assembly (GO:0090735)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a DNA repair complex.
MATH domain binding (GO:0090736)
Namespace: molecular_function
Definition: Binding to a meprin and TRAF homology (MATH) domain.
obsolete integral component of pigment granule membrane (GO:0090740)
Namespace: cellular_component
Definition: OBSOLETE. The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
pigment granule membrane (GO:0090741)
Namespace: cellular_component
Definition: Any membrane that is part of a pigment granule.
glycolysis from storage polysaccharide through glucose-1-phosphate (GO:0093001)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.
response to nematicide (GO:0093002)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.
Synonyms: response to antihelmintic; response to nematocide
acetylcholine receptor signaling pathway (GO:0095500)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
Synonyms: acetylcholine receptor signalling pathway
ceramide binding (GO:0097001)
Namespace: molecular_function
Definition: Binding to a ceramide, a class of lipids composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.
mitochondrial inner boundary membrane (GO:0097002)
Namespace: cellular_component
Definition: The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.
Synonyms: inner bounding mitochondrial membrane
adipokinetic hormone receptor activity (GO:0097003)
Namespace: molecular_function
Definition: Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are protein or peptide hormones that are important for sugar and fat homeostasis in metazoa. In insects, they mobilize sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
Synonyms: AKH receptor activity
adipokinetic hormone binding (GO:0097004)
Namespace: molecular_function
Definition: Binding to an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
Synonyms: AKH binding
regulation of plasma lipoprotein particle levels (GO:0097006)
Namespace: biological_process
Definition: Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.
Synonyms: plasma lipoprotein particle homeostasis
4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity (GO:0097007)
Namespace: molecular_function
Definition: Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.
Synonyms: 4,8,12-trimethyl-1,3,7,11-tridecatetraene synthase activity; TMTT synthase activity
(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity (GO:0097008)
Namespace: molecular_function
Definition: Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.
Synonyms: (3E)-4,8-dimethylnona-1,3,7-triene synthase activity; DNMT synthase activity