LiteFold/GO huggingface dataset:
radial spoke head 1 (GO:0120336)
Namespace: cellular_component
Definition: The portion of the radial spoke 1 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
Synonyms: radial spokehead 1
radial spoke head 2 (GO:0120337)
Namespace: cellular_component
Definition: The portion of the radial spoke 2 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
Synonyms: radial spokehead 2
radial spoke head 3 (GO:0120338)
Namespace: cellular_component
Definition: The portion of the radial spoke 3 that is orthogonal to the elongated stalk and which projects towards the central pair of microtubules within the ciliary axoneme.
Synonyms: radial spokehead 3
radial spoke base (GO:0120339)
Namespace: cellular_component
Definition: The short portion of the radial spoke that is directly anchored to the A microtubule of an axonemal microtubule doublet.
radial spoke base 1 (GO:0120340)
Namespace: cellular_component
Definition: The short portion of the radial spoke 1 (RS1) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
radial spoke base 2 (GO:0120341)
Namespace: cellular_component
Definition: The short portion of the radial spoke 2 (RS2) that is directly anchored to the A microtubule of an axonemal microtubule doublet.
radial spoke base 3 (GO:0120342)
Namespace: cellular_component
Definition: The short portion of the radial spoke 3 (RS3 )that is directly anchored to the A microtubule of an axonemal microtubule doublet.
radial spoke neck (GO:0120343)
Namespace: cellular_component
Definition: The radial spoke neck is a complex that connects the spoke stalk to the head.
NAE1-UBA3 complex (GO:0120500)
Namespace: cellular_component
Definition: A heterodimeric E1 complex that activates the ubiquitin-like protein NEDD8. In humans the subunits are NAE1 (also known as APPBP1) and UBA3.
Synonyms: APPBP1-UBA3 complex; NAE; NEDD8 activating enzyme
F-actin monooxygenase activity (GO:0120501)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-methionyl-[F-actin] + NADPH + O2 + H+ = L-methionyl-(R)-S-oxide-[F-actin] + NADP+ + H2O.
fatty acid omega-1 hydroxylase activity (GO:0120502)
Namespace: molecular_function
Definition: Catalysis of the reaction: an (omega-1)-ethyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an (omega-1)-hydroxy fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
medium-chain fatty acid omega-1 hydroxylase activity (GO:0120503)
Namespace: molecular_function
Definition: Catalysis of the reaction: an (omega-1)-ethyl medium-chain fatty acid + O2 + reduced [NADPH-hemoprotein reductase] = an (omega-1)-hydroxy-medium-chain fatty acid + H+ + H2O + oxidized [NADPH-hemoprotein reductase. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
EXT1-EXT2 complex (GO:0120504)
Namespace: cellular_component
Definition: A heterodimeric complex capable of glycosyltransferase activity required for the elongation of heparan sulfate chains. In humans, the complex consists of EXT1 and EXT2. In Drosophila, the complex consists of ttv and sotv.
Synonyms: exostosin complex; EXT1-EXT2 heparan sulfate biosynthesis complex
histone H3K79 monomethyltransferase activity (GO:0120505)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-lysyl79-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl79-[histone H3] + S-adenosyl-L-homocysteine.
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
tRNA-guanine transglycosylase complex (GO:0120507)
Namespace: cellular_component
Definition: A protein complex that catalyzes the base-exchange of a guanine residue with queuine at the wobble position of the anticodon of tRNAs. The eukaryotic tRNA-guanine transglycosylase exists as a heterodimer of a catalytic subunit (QTRT1 in humans) and an accessory subunit (QTRT2 in humans), whereas the bacterial enzyme is homodimeric.
Synonyms: queuine tRNA-ribosyltransferase complex; TGT
GDP-mannose pyrophosphorylase complex (GO:0120508)
Namespace: cellular_component
Definition: A protein complex capable of catalyzing the reaction of GTP and mannose-1-phosphate to form GDP-mannose. The complex is a homodimer in most bacteria and a heterodimer in most eukaryotes. In humans, it is composed of a catalytic beta subunit (GMPPB) and a regulatory alpha subunit (GMPPA).
Synonyms: GMPPA-GMPPB complex
methyl farnesoate epoxidase activity (GO:0120511)
Namespace: molecular_function
Definition: Catalysis of the reaction: methyl (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III + oxidized [NADPH--hemoprotein reductase].
Synonyms: CYP15A1 activity
farnesoate epoxidase activity (GO:0120512)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase].
Synonyms: CYP15C1 activity
2-(3-amino-3-carboxypropyl)histidine synthase complex (GO:0120513)
Namespace: cellular_component
Definition: A protein complex capable of catalysing the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the histidine residue of translation elongation factor 2 (EF2), which is the first step in the biosynthesis of diphthamide. The complex is a Dph2 homodimer in archaea and a Dph1-Dph2 heterodimer in eukaryotes.
Synonyms: Dph1-Dph2 complex
2-hydroxyflavanone C-glucosyltransferase activity (GO:0120514)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 3'-hydro-2'-hydroxy-beta-oxodihydrochalcone + UDP-alpha-D-glucose = a 3'-(beta-D-glucopyranosyl)-2'-hydroxy-beta-oxodihydrochalcone + H+ + UDP.
fatty acid-CoA ligase activity (GO:0120515)
Namespace: molecular_function
Definition: Catalysis of the reaction: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate.
diacylglycerol lipase activity (GO:0120516)
Namespace: molecular_function
Definition: Catalysis of the reaction: a diacylglycerol + H2O = a fatty acid + a monoacylglycerol + H+.
protein N-terminal-methionine acetyltransferase activity (GO:0120518)
Namespace: molecular_function
Definition: Catalysis of the reaction: acetyl-CoA + N-terminal L-methionyl-[protein] = CoA + H+ + N-terminal N(alpha)-acetyl-L-methionyl-[protein].
Synonyms: peptide-methionine-alpha-N-acetyltransferase activity
free fatty acid 2-hydroxylase activity (GO:0120520)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O. Note that the substrate is a free fatty acid, not a fatty acyl chain within a sphingolipid.
4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity (GO:0120521)
Namespace: molecular_function
Definition: Catalysis of the reaction: an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an N-(2R-hydroxyacyl)-4R-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O.
short-chain fatty acyl-CoA oxidase activity (GO:0120522)
Namespace: molecular_function
Definition: Catalysis of the reaction: a short-chain 2,3-saturated fatty acyl-CoA + O2 = a short-chain (2E)-enoyl-CoA + H2O2.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
medium-chain fatty acyl-CoA oxidase activity (GO:0120523)
Namespace: molecular_function
Definition: Catalysis of the reaction: a medium-chain 2,3-saturated fatty acyl-CoA + O2 = a medium-chain (2E)-enoyl-CoA + H2O2.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
long-chain fatty acyl-CoA oxidase activity (GO:0120524)
Namespace: molecular_function
Definition: Catalysis of the reaction: a long-chain 2,3-saturated fatty acyl-CoA + O2 = a long-chain (2E)-enoyl-CoA + H2O2.
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
choline trimethylamine lyase activity (GO:0120525)
Namespace: molecular_function
Definition: Catalysis of the reaction: choline = acetaldehyde + trimethylamine.
homomethionine N-monooxygenase activity (GO:0120526)
Namespace: molecular_function
Definition: Catalysis of the reaction: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase].
2-(omega-methylthio)alkylmalate dehydratase activity (GO:0120528)
Namespace: molecular_function
Definition: Catalysis of the reactions: a 2-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O and a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O.
secoisolariciresinol dehydrogenase activity (GO:0120529)
Namespace: molecular_function
Definition: Catalysis of the reaction: (-)-secoisolariciresinol + 2 NAD+ = (-)-matairesinol + 2 H(+) + 2 NADH.
UDP-alpha-D-glucose biosynthetic process (GO:0120530)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of UDP-alpha-D-glucose, a substance composed of alpha-D-glucose in glycosidic linkage with uridine diphosphate.
Synonyms: UDP-D-glucose biosynthesis; UDP-D-glucose biosynthetic process; UDP-glucose biosynthesis; uridine diphosphate glucose biosynthesis; uridine diphosphate glucose biosynthetic process
prenyl diphosphate synthase activity (GO:0120531)
Namespace: molecular_function
Definition: Catalysis of chain elongation of prenyl diphosphate substrates via one or more condensation reactions with isopentenyl diphosphate to generate linear polymers with defined chain lengths.
Synonyms: IPPS activity; isoprenyl pyrophosphate synthase activity
glycosaminoglycan-protein linkage region biosynthetic process (GO:0120532)
Namespace: biological_process
Definition: The formation of a tetrasaccharide linker sequence (xylose-galactose-galactose-glucuronate) on specific serine residues of a core protein, on to which dermatan sulfate, chondroitin sulfate, heparan sulfate or heparin glycosaminoglycans may be assembled to synthesise the corresponding proteoglycan.
Synonyms: Glycosaminoglycan biosynthesis, linkage tetrasaccharide; glycosaminoglycan-protein linkage region biosynthesis
dermatan sulfotransferase activity (GO:0120534)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan sulfate.
heptaprenylglyceryl phosphate synthase activity (GO:0120536)
Namespace: molecular_function
Definition: Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate = 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate.
Synonyms: glycerol-1-phosphate heptaprenyltransferase activity; HepGP synthase activity
3-demethylubiquinone 3-O-methyltransferase activity (GO:0120537)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine.
2-methoxy-6-polyprenolphenol 4-hydroxylase activity (GO:0120538)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H+ = 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O.
4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity (GO:0120539)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H+ = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2.
obsolete chondroitin sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0120540)
Namespace: biological_process
Definition: OBSOLETE. The modification, often by sulfation, of sugars in the polysaccharide chain component of chondroitin sulfate proteoglycans.
Comment: This term was obsoleted because it is a subprocess of chondroitin sulfate proteoglycan biosynthetic process ; GO:0050650.
obsolete dermatan sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0120541)
Namespace: biological_process
Definition: OBSOLETE. The modification, often by sulfation, of sugars in the polysaccharide chain component of dermatan sulfate proteoglycans.
Comment: This term was obsoleted because it is a subprocess of dermatan sulfate proteoglycan biosynthetic process ; GO:0050651.
ethanol dehydrogenase (NAD+) activity (GO:0120542)
Namespace: molecular_function
Definition: Catalysis of the reaction: ethanol + NAD+ = acetaldehyde + NADH + H+.
macromolecular conformation isomerase activity (GO:0120543)
Namespace: molecular_function
Definition: Catalysis of a reaction that alters the macromolecular conformation of a molecule.
polypeptide conformation or assembly isomerase activity (GO:0120544)
Namespace: molecular_function
Definition: Catalysis of a reaction that alters the conformation or assembly of a polypeptide.
oxidoreductase activity, reducing C-O-C group as acceptor (GO:0120546)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which a reducing C-O-C group acts as acceptor.
heme A synthase activity (GO:0120547)
Namespace: molecular_function
Definition: Catalysis of the reaction: Fe(II)-heme o + 2 acceptor + H2O = Fe(II)-heme a + 2 acceptor-H2. The conversion of heme o to heme a occcurs by two successive hydroxylations of the methyl group at C8 using water as the oxygen source. The first hydroxylation forms heme i, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
limit dextrin alpha-1,6-maltotetraose-hydrolase activity (GO:0120549)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages to branches with degrees of polymerization of three or four glucose residues in limit dextrin.
Synonyms: glycogen debranching enzyme
methyltransferase cap2 activity (GO:0120550)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA or snRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA or snRNA + S-adenosyl-L-homocysteine + H+. This activity catalyzes the methylation of the ribose on the second transcribed nucleotide of mRNAs and snRNAs.
Synonyms: cap2-MTase activity; mRNA (nucleoside-2'-O-)-methyltransferase activity
2-oxoglutarate decarboxylation to succinyl-CoA (GO:0120551)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of succinyl-CoA from 2-oxoglutarate.  In most organisms, this pathway is part of the TCA cycle and comprises a series of three reactions carried out by a multisubunit complex called the '2-oxoglutarate dehydrogenase complex', even though 2-oxoglutarate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: 2-oxoglutarate + coenzyme A + NAD+ -> succinyl-CoA + CO2 + NADH.
Synonyms: 2-ketoglutarate dehydrogenase system; 2-oxoglutarate dehydrogenase system; 2alpha-ketoglutarate dehydrogenase system
branched-chain alpha-keto acid decarboxylation to branched-chain acyl-CoA (GO:0120552)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a branched-chain acyl-CoA by the oxidative decarboxylation of a branched-chain alpha-keto acid derived from L-leucine, L-isoleucine or L-valine. This pathway comprises a series of three reactions carried out by a multisubunit complex called the 'branched-chain alpha-keto acid dehydrogenase complex', even though branched-chain alpha-keto acid dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: 3-methyl-2-oxobutanoate + coenzyme A + NAD+ -> branched-chain acyl-CoA + CO2 + NADH. Specific substrates include 3-methyl-2-oxobutanoate (a transamination product of L-valine), (S)-3-methyl-2-oxopentanoate (a transamination product of L-isoleucine) and 4-methyl-2-oxopentanoate (a transamination product of L-leucine), which generate the products 2-methylpropanoyl-CoA, 2-methylbutanoyl-CoA and 3-methylbutanoyl-CoA, respectively.
Synonyms: branched-chain 2-oxo acid dehydrogenase system; branched-chain alpha-keto acid dehydrogenase system
farnesal dehydrogenase (NAD+) activity (GO:0120553)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2E,6E)-farnesal + NAD+ + H2O = (2E,6E)-farnesoate + NADH + 2 H+.
(2S)-2-aminobutanoate:2-oxoglutarate transaminase activity (GO:0120554)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2S)-2-aminobutanoate + 2-oxoglutarate = 2-oxobutanoate + L-glutamate.
Synonyms: 2-aminobutanoate transaminase activity
polyprenyl diphosphate phosphatase activity (GO:0120556)
Namespace: molecular_function
Definition: Catalysis of the dephosphorylation of polyprenyl diphosphates.
farnesyl diphosphatase activity (GO:0120557)
Namespace: molecular_function
Definition: Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + phosphate + H+.
lysophospholipase A1 activity (GO:0120558)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a lysoglycerophospholipid, removing the acyl chain at the sn-1 position to yield a glycerophospho-compound and a free fatty acid.
phosphatidylethanolamine lysophospholipase A1 activity (GO:0120559)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O = sn-glycero-3-phosphoethanolamine + a fatty acid + H+.
Synonyms: phosphatidylethanolamine lysophospholipase A1-type activity; phosphatidylethanolamine lysophospholipase activity
phosphatidylserine lysophospholipase A1 activity (GO:0120560)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O = sn-glycero-3-phospho-L-serine + a fatty acid + H+.
Synonyms: phosphatidylserine lysophospholipase A1-type activity; phosphatidylserine sn-1 acylhydrolase; phosphatidylserine-specific phospholipase A1
phosphatidylinositol lysophospholipase A1 activity (GO:0120561)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H+.
Synonyms: phosphatidylinositol lysophospholipase A1-type activity
GlcNAc(2)-PP-Dol mannosyltransferase activity (GO:0120562)
Namespace: molecular_function
Definition: Catalysis of the transfer of a mannosyl residue to GlcNAc(2)-PP-Dol bearing 0-8 mannoses during synthesis of the N-glycan precursor.
dol-P-Man:Man(2)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity (GO:0120564)
Namespace: molecular_function
Definition: Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to Man(2)-GlcN-acyl-PI, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. This transfers the third mannose to the GPI precursor.
Synonyms: glycosylphosphatidylinositol-mannosyltransferase III activity; GPI-MT-III activity
dol-P-Man:Man(3)GlcN-acyl-PI alpha-1,2-mannosyltransferase activity (GO:0120565)
Namespace: molecular_function
Definition: Catalysis of the transfer of an alpha-D-mannosyl residue from dolichol-P-mannose to Man(3)-GlcN-acyl-PI, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage. This transfers a fourth mannose to the GPI precursor, which is only present in some organisms/cell types.
Synonyms: glycosylphosphatidylinositol-mannosyltransferase IV activity; GPI-MT-IV activity
menadiol geranylgeranyltransferase activity (GO:0120566)
Namespace: molecular_function
Definition: Catalysis of the reaction: menadiol + (2E,6E,10E)-geranylgeranyl diphosphate = menaquinol-4 + diphosphate.
hydroxytrimethyllysine aldolase activity (GO:0120567)
Namespace: molecular_function
Definition: Catalysis of the reaction: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine = 4-(trimethylamino)butanal + glycine.
Synonyms: HTMLA
(R)-2-hydroxyglutarate (NAD+) dehydrogenase activity (GO:0120568)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-2-hydroxyglutarate + NAD+ = 2-oxoglutarate + NADH + H+.
Synonyms: 2-oxoglutarate reductase activity
phospholipase activity (GO:0120569)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a phospholipid.
sphingophospholipase activity (GO:0120570)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of a sphingophospholipid.
dihydrolipoyllysine-residue glutaryltransferase activity (GO:0120571)
Namespace: molecular_function
Definition: Catalysis of the reaction: N6-[(R)-dihydrolipoyl]-L-lysyl-[protein] + glutaryl-CoA = CoA + N6-[(R)-S8-glutaryldihydrolipoyl]-L-lysyl-[protein].
L-lactate oxidase activity (GO:0120572)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-lactate + O2 = pyruvate + H2O2.
FAHFA hydrolase activity (GO:0120573)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of the ester bond in a fatty acid ester of a hydroxy fatty acid (FAHFA), yielding a free fatty acid and a hydroxy fatty acid. FAHFAs are a class of endogenous bioactive signaling lipids in which a fatty acid is esterified to a hydroxyl group on a second fatty acid backbone.
Synonyms: fatty-acid ester of hydroxy-fatty-acid hydrolase activity
L-dopa catabolic process (GO:0120575)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-dopa.
morula formation (GO:0140001)
Namespace: biological_process
Definition: The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum.
histone H3K4me3 reader activity (GO:0140002)
Namespace: molecular_function
Definition: A histone reader that recognizes a histone H3 trimethylated at lysine 4.
Synonyms: H3-K4me3 modified histone binding; H3K4me3 modified histone binding
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
histone H3K36me3 reader activity (GO:0140003)
Namespace: molecular_function
Definition: A histone reader that recognizes a histone H3 trimethylated at lysine 36.
Synonyms: H3-K36me3 modified histone binding; H3K36me3 modified histone binding
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.