LiteFold/GO huggingface dataset:
mitochondrial translational termination (GO:0070126)
Namespace: biological_process
Definition: The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
Synonyms: mitochondrial translation termination
tRNA aminoacylation for mitochondrial protein translation (GO:0070127)
Namespace: biological_process
Definition: The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
regulation of mitochondrial translation (GO:0070129)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
Synonyms: regulation of mitochondrial protein anabolism; regulation of mitochondrial protein biosynthesis; regulation of mitochondrial protein formation; regulation of mitochondrial protein synthesis
negative regulation of mitochondrial translation (GO:0070130)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
Synonyms: negative regulation of mitochondrial protein anabolism; negative regulation of mitochondrial protein biosynthesis; negative regulation of mitochondrial protein formation; negative regulation of mitochondrial protein synthesis
positive regulation of mitochondrial translation (GO:0070131)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
Synonyms: positive regulation of mitochondrial protein anabolism; positive regulation of mitochondrial protein biosynthesis; positive regulation of mitochondrial protein formation; positive regulation of mitochondrial protein synthesis
regulation of mitochondrial translational initiation (GO:0070132)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
Synonyms: regulation of mitochondrial translation initiation
negative regulation of mitochondrial translational initiation (GO:0070133)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
Synonyms: negative regulation of mitochondrial translation initiation
positive regulation of mitochondrial translational initiation (GO:0070134)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
Synonyms: positive regulation of mitochondrial translation initiation
beta-1,2-oligomannoside metabolic process (GO:0070135)
Namespace: biological_process
Definition: The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
Synonyms: beta-1,2-oligomannoside metabolism
beta-1,2-oligomannoside biosynthetic process (GO:0070136)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
Synonyms: beta-1,2-oligomannoside anabolism; beta-1,2-oligomannoside biosynthesis; beta-1,2-oligomannoside formation; beta-1,2-oligomannoside synthesis
ubiquitin-like protein-specific endopeptidase activity (GO:0070137)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).
Synonyms: small conjugating protein-specific endopeptidase activity
SUMO-specific endopeptidase activity (GO:0070139)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.
response to UV-A (GO:0070141)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
Synonyms: response to UV-A light stimulus; response to UV-A radiation stimulus; response to UVA light stimulus; response to UVA radiation stimulus
synaptic vesicle budding (GO:0070142)
Namespace: biological_process
Definition: Evagination of a membrane to form a synaptic vesicle.
mitochondrial alanyl-tRNA aminoacylation (GO:0070143)
Namespace: biological_process
Definition: The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial arginyl-tRNA aminoacylation (GO:0070144)
Namespace: biological_process
Definition: The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial asparaginyl-tRNA aminoacylation (GO:0070145)
Namespace: biological_process
Definition: The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial aspartyl-tRNA aminoacylation (GO:0070146)
Namespace: biological_process
Definition: The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial cysteinyl-tRNA aminoacylation (GO:0070147)
Namespace: biological_process
Definition: The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glutaminyl-tRNA aminoacylation (GO:0070148)
Namespace: biological_process
Definition: The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glutamyl-tRNA aminoacylation (GO:0070149)
Namespace: biological_process
Definition: The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial glycyl-tRNA aminoacylation (GO:0070150)
Namespace: biological_process
Definition: The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial histidyl-tRNA aminoacylation (GO:0070151)
Namespace: biological_process
Definition: The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial isoleucyl-tRNA aminoacylation (GO:0070152)
Namespace: biological_process
Definition: The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial leucyl-tRNA aminoacylation (GO:0070153)
Namespace: biological_process
Definition: The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial lysyl-tRNA aminoacylation (GO:0070154)
Namespace: biological_process
Definition: The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial methionyl-tRNA aminoacylation (GO:0070155)
Namespace: biological_process
Definition: The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial phenylalanyl-tRNA aminoacylation (GO:0070156)
Namespace: biological_process
Definition: The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial prolyl-tRNA aminoacylation (GO:0070157)
Namespace: biological_process
Definition: The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial seryl-tRNA aminoacylation (GO:0070158)
Namespace: biological_process
Definition: The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial threonyl-tRNA aminoacylation (GO:0070159)
Namespace: biological_process
Definition: The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
anchoring junction (GO:0070161)
Namespace: cellular_component
Definition: A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
Synonyms: anchoring cell junction
adiponectin secretion (GO:0070162)
Namespace: biological_process
Definition: The regulated release of adiponectin, a protein hormone, by adipose tissue.
regulation of adiponectin secretion (GO:0070163)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.
negative regulation of adiponectin secretion (GO:0070164)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.
Synonyms: down regulation of adiponectin secretion; down-regulation of adiponectin secretion; downregulation of adiponectin secretion; inhibition of adiponectin secretion
positive regulation of adiponectin secretion (GO:0070165)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.
Synonyms: activation of adiponectin secretion; stimulation of adiponectin secretion; up regulation of adiponectin secretion; up-regulation of adiponectin secretion; upregulation of adiponectin secretion
enamel mineralization (GO:0070166)
Namespace: biological_process
Definition: The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
Synonyms: enamel formation
regulation of biomineral tissue development (GO:0070167)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
negative regulation of biomineral tissue development (GO:0070168)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
positive regulation of biomineral tissue development (GO:0070169)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
regulation of tooth mineralization (GO:0070170)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
negative regulation of tooth mineralization (GO:0070171)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
positive regulation of tooth mineralization (GO:0070172)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
regulation of enamel mineralization (GO:0070173)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
negative regulation of enamel mineralization (GO:0070174)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
positive regulation of enamel mineralization (GO:0070175)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
DRM complex (GO:0070176)
Namespace: cellular_component
Definition: A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.
Synonyms: DP/Rb/MuvB
contractile vacuole discharge (GO:0070177)
Namespace: biological_process
Definition: The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.
obsolete D-serine metabolic process (GO:0070178)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.
Synonyms: D-serine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
D-serine biosynthetic process (GO:0070179)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.
Synonyms: D-serine anabolism; D-serine biosynthesis; D-serine formation; D-serine synthesis
large ribosomal subunit rRNA binding (GO:0070180)
Namespace: molecular_function
Definition: Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
Synonyms: 25S rRNA binding; LSU rRNA binding
DNA polymerase binding (GO:0070182)
Namespace: molecular_function
Definition: Binding to a DNA polymerase.
mitochondrial tryptophanyl-tRNA aminoacylation (GO:0070183)
Namespace: biological_process
Definition: The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
mitochondrial valyl-tRNA aminoacylation (GO:0070185)
Namespace: biological_process
Definition: The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
growth hormone activity (GO:0070186)
Namespace: molecular_function
Definition: The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.
Synonyms: GH activity; pituitary growth hormone activity; placental growth hormone activity
shelterin complex (GO:0070187)
Namespace: cellular_component
Definition: A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Saccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.
Synonyms: Pot1 complex; Pot1-Tpz1 complex; telosome
obsolete Stn1-Ten1 complex (GO:0070188)
Namespace: cellular_component
Definition: OBSOLETE. A nuclear telomere cap complex that is formed by the association of the Stn1 and Ten1 proteins with telomeric DNA; in some species a third protein is present.
Comment: This term was made obsolete because it was inaccurate.
kynurenine metabolic process (GO:0070189)
Namespace: biological_process
Definition: The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
Synonyms: kynurenine metabolism
obsolete inositol hexakisphosphate 1-kinase or 3-kinase activity (GO:0070190)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate, and ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.
Synonyms: inositol hexakisphosphate 1-kinase or 3-kinase activity
Comment: This term was made obsolete because it represents two reactions, and should be two separate terms.
obsolete methionine-R-sulfoxide reductase activity (GO:0070191)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.
Comment: The reason for obsoletion is that this term is equivalent to GO:0033745 L-methionine-(R)-S-oxide reductase activity.
chromosome organization involved in meiotic cell cycle (GO:0070192)
Namespace: biological_process
Definition: A process of chromosome organization that is involved in a meiotic cell cycle.
Synonyms: chromosome organisation involved in meiosis; meiotic chromosome organization
synaptonemal complex organization (GO:0070193)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.
Synonyms: synaptonemal complex organisation
synaptonemal complex disassembly (GO:0070194)
Namespace: biological_process
Definition: The controlled breakdown of a synaptonemal complex.
eukaryotic translation initiation factor 3 complex assembly (GO:0070196)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.
Synonyms: eIF-3 assembly; eIF3 assembly
meiotic attachment of telomere to nuclear envelope (GO:0070197)
Namespace: biological_process
Definition: The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.
Synonyms: attachment of telomeres to nuclear envelope; attachment of telomeric chromatin to nuclear envelope
protein localization to chromosome, telomeric region (GO:0070198)
Namespace: biological_process
Definition: Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
Synonyms: protein localisation to chromosome, telomeric region; protein localization to telomere
establishment of protein localization to chromosome (GO:0070199)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location on a chromosome.
Synonyms: establishment of protein localisation to chromosome
establishment of protein localization to telomere (GO:0070200)
Namespace: biological_process
Definition: The directed movement of a protein to a specific location in the telomeric region of a chromosome.
Synonyms: establishment of protein localisation to telomere; establishment of protein localization to chromosome, telomeric region
regulation of establishment of protein localization (GO:0070201)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
Synonyms: regulation of establishment of protein localisation
regulation of establishment of protein localization to chromosome (GO:0070202)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
Synonyms: regulation of establishment of protein localisation to chromosome
regulation of establishment of protein localization to telomere (GO:0070203)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.
Synonyms: regulation of establishment of protein localisation to telomere