LiteFold/GO huggingface dataset:
germ cell proliferation (GO:0036093)
Namespace: biological_process
Definition: The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
small molecule binding (GO:0036094)
Namespace: molecular_function
Definition: Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.
Comment: Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides.
obsolete positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter (GO:0036095)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: transcriptional activation of genes involved in invasive growth
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing (GO:0036096)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming the mature 3' end of a miRNA from a pre-miRNA.
Synonyms: 3'-5'-exoribonuclease activity involved in pre-miRNA 3'-end processing; exonucleolytic trimming to generate 3' end of miRNA from pre-miRNA
Comment: This term was made obsolete because it is not real a process, and was created accidentally.
obsolete pre-miRNA 3'-end processing (GO:0036097)
Namespace: biological_process
Definition: OBSOLETE. Any process involved in forming the mature 3' end of a miRNA from a pre-miRNA.
Synonyms: microRNA 3'-end processing; miRNA 3'-end processing; pre-miRNA 3'-end processing
Comment: This term was made obsolete because it is not real a process, and was created accidentally.
female germ-line stem cell population maintenance (GO:0036099)
Namespace: biological_process
Definition: The process by which an organism or tissue maintains a population of female germ-line stem cells.
leukotriene catabolic process (GO:0036100)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
Synonyms: leukotriene breakdown; leukotriene catabolism; leukotriene degradation
leukotriene B4 catabolic process (GO:0036101)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
Synonyms: leukotriene B4 breakdown; leukotriene B4 catabolism; leukotriene B4 degradation; LTB4 catabolism
leukotriene B4 metabolic process (GO:0036102)
Namespace: biological_process
Definition: The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
Synonyms: LTB4 metabolism
Kdo2-lipid A biosynthetic process (GO:0036104)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.
Synonyms: 3-deoxy-d-manno-octulosonic acid-lipid A biosynthesis; Kdo2-lipid A anabolism; Kdo2-lipid A biosynthesis; Kdo2-lipid A formation; Kdo2-lipid A synthesis
peroxisome membrane class-2 targeting sequence binding (GO:0036106)
Namespace: molecular_function
Definition: Binding to a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner.
Synonyms: class 2 mPTS binding; PEX19-independent mPTS binding
Comment: Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.
4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process (GO:0036108)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
Synonyms: 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate anabolism; 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthesis; 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate formation; 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate synthesis; undecaprenyl phosphate alpha-L-Ara4N biosynthesis
alpha-linolenic acid metabolic process (GO:0036109)
Namespace: biological_process
Definition: The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
Synonyms: ALA metabolism; alpha-linolenic acid metabolism
cellular response to inositol starvation (GO:0036110)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.
very long-chain fatty-acyl-CoA metabolic process (GO:0036111)
Namespace: biological_process
Definition: The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
Synonyms: very long-chain fatty acyl CoA metabolic process; very long-chain fatty acyl-CoA metabolism
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
medium-chain fatty-acyl-CoA metabolic process (GO:0036112)
Namespace: biological_process
Definition: The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
Synonyms: medium-chain fatty acyl CoA metabolic process; medium-chain fatty acyl-CoA metabolism
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
very long-chain fatty-acyl-CoA catabolic process (GO:0036113)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a very long-chain fatty-acyl group. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons.
Synonyms: very long-chain fatty-acyl-CoA breakdown; very long-chain fatty-acyl-CoA catabolism; very long-chain fatty-acyl-CoA degradation
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
medium-chain fatty-acyl-CoA catabolic process (GO:0036114)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid has an aliphatic tail containing 6 to 12 carbons.
Synonyms: medium-chain fatty-acyl-CoA breakdown; medium-chain fatty-acyl-CoA catabolism; medium-chain fatty-acyl-CoA degradation
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
fatty-acyl-CoA catabolic process (GO:0036115)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
Synonyms: fatty-acyl-CoA breakdown; fatty-acyl-CoA catabolism; fatty-acyl-CoA degradation
long-chain fatty-acyl-CoA catabolic process (GO:0036116)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: long-chain fatty-acyl-CoA breakdown; long-chain fatty-acyl-CoA catabolism; long-chain fatty-acyl-CoA degradation
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
hyaluranon cable (GO:0036117)
Namespace: cellular_component
Definition: A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
Synonyms: HA cable
hyaluranon cable assembly (GO:0036118)
Namespace: biological_process
Definition: A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
Synonyms: HA cable assembly
response to platelet-derived growth factor (GO:0036119)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
Synonyms: response to PDGF stimulus; response to platelet-derived growth factor stimulus
cellular response to platelet-derived growth factor stimulus (GO:0036120)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
Synonyms: cellular response to PDGF stimulus
double-stranded DNA helicase activity (GO:0036121)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.
Synonyms: double-stranded DNA-dependent ATP-dependent DNA helicase activity; double-stranded DNA-dependent ATPase activity; dsDNA-dependent ATP-dependent DNA helicase activity; dsDNA-dependent ATPase activity
BMP binding (GO:0036122)
Namespace: molecular_function
Definition: Binding to a member of the bone morphogenetic protein (BMP) family.
Synonyms: bone morphogenetic protein binding
obsolete histone H3-K9 dimethylation (GO:0036123)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone.
Synonyms: histone H3 K9 dimethylation; histone lysine H3 K9 dimethylation
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H3-K9 trimethylation (GO:0036124)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone.
Comment: This term was obsoleted because it represents a molecular function.
fatty acid beta-oxidation multienzyme complex (GO:0036125)
Namespace: cellular_component
Definition: A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).
Comment: For fatty acid beta-oxidation multienzyme complexes located in the mitochondrial matrix, consider instead the term 'mitochondrial fatty acid beta-oxidation multienzyme complex ; GO:0016507'.
sperm flagellum (GO:0036126)
Namespace: cellular_component
Definition: A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
Synonyms: sperm cilium; sperm tail
Comment: Note that cilia and eukaryotic flagella are deemed to be equivalent. In this case community usage is always 'flagellum', hence the primary term name, but the cilium parentage is deliberate.
3-sulfino-L-alanine binding (GO:0036127)
Namespace: molecular_function
Definition: Binding to 3-sulfino-L-alanine (cysteine sulfinate).
Synonyms: cysteine sulfinate binding
CatSper complex (GO:0036128)
Namespace: cellular_component
Definition: A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.
Synonyms: CATSPER channel; CatSper channel complex
obsolete negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide (GO:0036129)
Namespace: biological_process
Definition: OBSOLETE. Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.
Comment: This term was obsoleted because it represents a GO-CAM model.
prostaglandin H2 endoperoxidase reductase activity (GO:0036130)
Namespace: molecular_function
Definition: Catalysis of the reaction: prostaglandin F2alpha + NADP+ = prostaglandin H2 + NADPH + H+.
Synonyms: PGH2 9,11-endoperoxidase; PGH2 9-,11-endoperoxide reductase
prostaglandin D2 11-ketoreductase activity (GO:0036131)
Namespace: molecular_function
Definition: Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+.
Synonyms: PGD2 11-ketoreductase; prostaglandin 11-keto reductase
obsolete 13-prostaglandin reductase activity (GO:0036132)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.
Synonyms: 15-oxoprostaglandin 13-reductase activity
Comment: This term was obsoleted because it represents the same activity as 15-oxoprostaglandin 13-oxidase activity ; GO:0047522.
11-hydroxythromboxane B2 dehydrogenase activity (GO:0036133)
Namespace: molecular_function
Definition: Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.
Synonyms: NAD dependent 11-hydroxythromboxane B2 dehydrogenase activity
Comment: Note that the KEGG_REACTION:R05060 reaction does not stipulate the acceptor group, and is therefore slightly more general than the activity described by GO:0036133.
12-hydroxyheptadecatrienoic acid synthase activity (GO:0036134)
Namespace: molecular_function
Definition: Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).
Synonyms: prostaglandin H2 degradation activity
obsolete kynurenine-oxaloacetate transaminase activity (GO:0036136)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate.
Synonyms: L-kynurenine-oxaloacetate transaminase activity
Comment: This term was obsoleted because there is no evidence that this reaction exists.
obsolete kynurenine aminotransferase activity (GO:0036137)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid.
Synonyms: kynurenine-oxo-acid transaminase activity; L-kynurenine transaminase activity
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
obsolete peptidyl-histidine hydroxylation (GO:0036138)
Namespace: biological_process
Definition: OBSOLETE. The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.
Comment: This term was obsoleted because it represents a molecular function.
peptidyl-histidine dioxygenase activity (GO:0036139)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-histidyl-[protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[protein] + succinate + CO2.
Synonyms: protein histidyl hydroxylase; protein-L-histidine (3S)-3-hydroxylase
[protein]-asparagine 3-dioxygenase activity (GO:0036140)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.
Synonyms: hypoxia-inducible factor-asparagine oxygenase activity; peptidyl-asparagine 3-dioxygenase activity
kringle domain binding (GO:0036143)
Namespace: molecular_function
Definition: Binding to a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
dendritic cell homeostasis (GO:0036145)
Namespace: biological_process
Definition: The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Synonyms: DC homeostasis
cellular response to mycotoxin (GO:0036146)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
rumination (GO:0036147)
Namespace: biological_process
Definition: A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.
Synonyms: digestive rumination
phosphatidylglycerol acyl-chain remodeling (GO:0036148)
Namespace: biological_process
Definition: Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
Synonyms: phosphatidylglycerol acyl-chain remodelling
phosphatidylinositol acyl-chain remodeling (GO:0036149)
Namespace: biological_process
Definition: Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
Synonyms: phosphatidylinositol acyl-chain remodelling
phosphatidylserine acyl-chain remodeling (GO:0036150)
Namespace: biological_process
Definition: Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
Synonyms: phosphatidyl-L-serine acyl-chain remodeling; phosphatidylserine acyl-chain remodelling
phosphatidylcholine acyl-chain remodeling (GO:0036151)
Namespace: biological_process
Definition: Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
Synonyms: phosphatidylcholine acyl-chain remodelling
phosphatidylethanolamine acyl-chain remodeling (GO:0036152)
Namespace: biological_process
Definition: Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
Synonyms: phosphatidylethanolamine acyl-chain remodelling
triglyceride acyl-chain remodeling (GO:0036153)
Namespace: biological_process
Definition: Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.
Synonyms: triacylglycerol acyl-chain remodeling; triglyceride acyl-chain remodelling
diacylglycerol acyl-chain remodeling (GO:0036154)
Namespace: biological_process
Definition: Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.
Synonyms: diacylglycerol acyl-chain remodelling; diglyceride acyl-chain remodeling
acylglycerol acyl-chain remodeling (GO:0036155)
Namespace: biological_process
Definition: Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.
Synonyms: acylglycerol acyl-chain remodelling; glyceride acyl-chain remodeling
inner dynein arm (GO:0036156)
Namespace: cellular_component
Definition: Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
Synonyms: inner dynein arm complex
outer dynein arm (GO:0036157)
Namespace: cellular_component
Definition: Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
Synonyms: outer dynein arm complex
outer dynein arm assembly (GO:0036158)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
Synonyms: ODA assembly
inner dynein arm assembly (GO:0036159)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
Synonyms: IDA assembly
melanocyte-stimulating hormone secretion (GO:0036160)
Namespace: biological_process
Definition: The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.
Synonyms: MSH secretion