LiteFold/GO huggingface dataset:
obsolete anatomical structure formation (GO:0010926)
Namespace: biological_process
Definition: OBSOLETE. The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structure is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
Synonyms: anatomical structure formation
Comment: The reason for obsoletion is that the term is confusing - it sounds developmental and has a developmental sounding def, but it is not a child of developmental process and its children included 'cellular component assembly'. The term was created to group together 'cellular component assembly' and 'anatomical structure formation involved in morphogenesis', but we no longer feel that this grouping is useful.
obsolete regulation of cell death (GO:0010941)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
Comment: The reason for obsoletion is that this term represent an assay and not a GO process.
negative regulation of meiotic joint molecule formation (GO:0010947)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
negative regulation of cell cycle process (GO:0010948)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
negative regulation of neuron projection development (GO:0010977)
Namespace: biological_process
Definition: Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
Synonyms: growth cone collapse; negative regulation of neurite biosynthesis; negative regulation of neurite development; negative regulation of neurite formation; negative regulation of neurite growth
endomembrane system (GO:0012505)
Namespace: cellular_component
Definition: A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
astrocyte development (GO:0014002)
Namespace: biological_process
Definition: The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
Synonyms: astrocyte cell development
regulation of gliogenesis (GO:0014013)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.
acetylcholine secretion, neurotransmission (GO:0014055)
Namespace: biological_process
Definition: The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).
regulation of serotonin secretion (GO:0014062)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of serotonin.
Synonyms: regulation of serotonin release
obsolete response to organic cyclic compound (GO:0014070)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
Synonyms: response to organic cyclic substance
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
response to isoquinoline alkaloid (GO:0014072)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
oscillatory muscle contraction (GO:0014703)
Namespace: biological_process
Definition: A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.
C zone (GO:0014705)
Namespace: cellular_component
Definition: A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.
striated muscle tissue development (GO:0014706)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.
positive regulation of somitomeric trunk muscle development (GO:0014709)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
positive regulation of extraocular skeletal muscle development (GO:0014727)
Namespace: biological_process
Definition: Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
skeletal muscle regeneration at neuromuscular junction (GO:0014730)
Namespace: biological_process
Definition: The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.
regulation of muscle hyperplasia (GO:0014738)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of muscle hyperplasia.
positive regulation of muscle hyperplasia (GO:0014739)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.
skeletal muscle satellite cell commitment (GO:0014813)
Namespace: biological_process
Definition: The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.
axon regeneration at neuromuscular junction (GO:0014814)
Namespace: biological_process
Definition: The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.
response to activity (GO:0014823)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
Synonyms: response to exercise
myoblast proliferation involved in skeletal muscle regeneration (GO:0014844)
Namespace: biological_process
Definition: The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
myoblast division (GO:0014872)
Namespace: biological_process
Definition: The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
obsolete response to stimulus involved in regulation of muscle adaptation (GO:0014874)
Namespace: biological_process
Definition: OBSOLETE. Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.
Synonyms: response to stimulus involved in regulation of muscle plasticity
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
muscle hypertrophy (GO:0014896)
Namespace: biological_process
Definition: The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
myotube cell development (GO:0014904)
Namespace: biological_process
Definition: The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
obsolete myoblast maturation involved in muscle regeneration (GO:0014914)
Namespace: biological_process
Definition: OBSOLETE. A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
heparan sulfate N-sulfotransferase activity (GO:0015016)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n) = adenosine 3',5'-bisphosphate + 2 H+ + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n).
Synonyms: 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine N-sulfotransferase activity; 3'-phosphoadenylyl-sulfate:heparitin N-sulfotransferase activity; 3'-phosphoadenylyl-sulfate:N-desulfoheparin N-sulfotransferase activity; 3'-phosphoadenylylsulfate:N-desulfoheparin sulfotransferase activity; [heparan sulfate]-glucosamine N-sulfotransferase activity; [heparan sulphate]-glucosamine N-sulphotransferase activity; desulfoheparin sulfotransferase activity; glucosaminyl N-deacetylase/N-sulfotransferase activity; heparan sulfate 2-N-sulfotransferase activity; heparan sulfate N-deacetylase/N-sulfotransferase activity; heparin N-deacetylase/N-sulfotransferase activity; heparin N-deacetylase/N-sulphotransferase activity; heparin N-sulfotransferase activity; heparin-glucosamine N-sulfotransferase activity; heparitin N-sulfotransferase activity; heparitin N-sulphotransferase activity; heparitin sulfotransferase activity; N-desulfoheparin sulfotransferase activity; N-heparan sulfate sulfotransferase activity; N-HSST activity; PAPS:DSH sulfotransferase activity; PAPS:N-desulfoheparin sulfotransferase activity
Comment: Note that this activity includes EC:2.8.2.12 (deleted from EC).
heparan-alpha-glucosaminide N-acetyltransferase activity (GO:0015019)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-D-glucosaminyl-[heparan sulfate](n) + acetyl-CoA = N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) + CoA + H+.
Synonyms: acetyl-CoA:alpha-glucosaminide N-acetyltransferase activity; acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase activity; heparin-alpha-glucosaminide N-acetyltransferase activity
obsolete NADPH-adrenodoxin reductase activity (GO:0015039)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.
Synonyms: adrenodoxin reductase activity; adrenodoxin-type ferredoxin reductase activity; NADPH:adrenodoxin oxidoreductase activity
Comment: The reason for obsoletion is that this term is equivalent to ferredoxin-NADP+ reductase activity.
methane monooxygenase [NAD(P)H] activity (GO:0015049)
Namespace: molecular_function
Definition: Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.
Synonyms: methane hydroxylase activity; methane,NAD(P)H:oxygen oxidoreductase (hydroxylating)
obsolete opsin (GO:0015053)
Namespace: molecular_function
Definition: OBSOLETE. Hydrophobic glycoprotein to which 11-cis-retinal binds as a Schiff base (in rhodopsin) or 3,4-didehydro-11-cis-retinal binds as a Schiff base in cyanopsin and porphyropsin.
Synonyms: opsin
Comment: This term was made obsolete because it refers to a class of proteins.
amidinotransferase activity (GO:0015067)
Namespace: molecular_function
Definition: Catalysis of the reversible transfer of an amidino group to an acceptor.
Synonyms: transamidinase activity
scyllo-inosamine-4-phosphate amidinotransferase activity (GO:0015069)
Namespace: molecular_function
Definition: Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.
Synonyms: inosamine-P amidinotransferase activity; inosamine-phosphate amidinotransferase activity; L-arginine:1-amino-1-deoxy-scyllo-inositol-4-phosphate amidinotransferase activity; L-arginine:inosamine phosphate amidinotransferase activity; L-arginine:inosamine-P-amidinotransferase activity
obsolete phosphatidylinositol 3-kinase, class I, regulator activity (GO:0015073)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.
Synonyms: phosphatidylinositol 3-kinase, class I, regulator activity
Comment: This term was made obsolete because it refers to a class of gene products.
aluminum ion transmembrane transporter activity (GO:0015083)
Namespace: molecular_function
Definition: Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.
Synonyms: aluminium ion transporter activity; aluminium resistance permease activity; aluminum resistance permease activity
obsolete inorganic anion transmembrane transporter activity (GO:0015103)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
Comment: The reason for obsoletion is that this term was an unnecessary and confusing grouping term.
bicarbonate transmembrane transporter activity (GO:0015106)
Namespace: molecular_function
Definition: Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
Synonyms: hydrogencarbonate transmembrane transporter activity
obsolete phosphate ion transmembrane transporter activity (GO:0015114)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of phosphate ions from one side of a membrane to the other.
Synonyms: phosphate transmembrane transporter activity
Comment: This term was obsoleted because it represents the same activity as phosphate transmembrane transporter activity ; GO:0005315 (phosphate ion == inorganic phosphate).
canalicular bile acid transmembrane transporter activity (GO:0015126)
Namespace: molecular_function
Definition: The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
gluconate transmembrane transporter activity (GO:0015128)
Namespace: molecular_function
Definition: Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.
Synonyms: L-idonate/D-gluconate:hydrogen symporter activity
mevalonate transmembrane transporter activity (GO:0015130)
Namespace: molecular_function
Definition: Enables the transfer of mevalonate from one side of a membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.
Synonyms: monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
glucuronate transmembrane transporter activity (GO:0015135)
Namespace: molecular_function
Definition: Enables the transfer of glucuronate from one side of a membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
monosaccharide transmembrane transporter activity (GO:0015145)
Namespace: molecular_function
Definition: Enables the transfer of a monosaccharide from one side of a membrane to the other.
oligosaccharide transmembrane transporter activity (GO:0015157)
Namespace: molecular_function
Definition: Enables the transfer of oligosaccharide from one side of a membrane to the other.
Synonyms: endosomal oligosaccharide transporter
pyrimidine nucleotide-sugar transmembrane transporter activity (GO:0015165)
Namespace: molecular_function
Definition: Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
L-cystine transmembrane transporter activity (GO:0015184)
Namespace: molecular_function
Definition: Enables the transfer of L-cystine from one side of a membrane to the other.
Synonyms: cystine/diaminopimelate porter activity; L-cystine transporter activity
pyrimidine nucleoside transmembrane transporter activity (GO:0015214)
Namespace: molecular_function
Definition: Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.
purine nucleotide transmembrane transporter activity (GO:0015216)
Namespace: molecular_function
Definition: Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
cycloheximide transmembrane transporter activity (GO:0015243)
Namespace: molecular_function
Definition: Enables the transfer of cycloheximide from one side of a membrane to the other. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
Synonyms: cycloheximide transporter activity
calcium-activated potassium channel activity (GO:0015269)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a potassium cation by a channel that opens when a calcium cation has been bound by the channel complex or one of its constituent parts.
uniporter activity (GO:0015292)
Namespace: molecular_function
Definition: Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.
Synonyms: facilitated diffusion carrier; single-species transporter activity; uniport
polyamine:proton antiporter activity (GO:0015312)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
Synonyms: polyamine:hydrogen antiporter activity
aminotriazole:proton antiporter activity (GO:0015314)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).
Synonyms: aminotriazole:hydrogen antiporter activity
obsolete inorganic molecular entity transmembrane transporter activity (GO:0015318)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.
Synonyms: inorganic solute uptake transmembrane transporter activity; inorganic uptake permease activity
Comment: The reason for obsoletion is that this term was an unnecessary and confusing grouping term.
peptide:proton symporter activity (GO:0015333)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in), up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.
Synonyms: peptide:hydrogen symporter activity
low-affinity sodium:dicarboxylate symporter activity (GO:0015361)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
Synonyms: low affinity sodium:dicarboxylate cotransporter activity; low affinity sodium:dicarboxylate symporter activity