LiteFold/GO huggingface dataset:
obsolete dicarboxylate (succinate/fumarate/malate) antiporter activity (GO:0015363)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: dicarboxylate (succinate/fumarate/malate) antiporter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
galactose:sodium symporter activity (GO:0015371)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).
obsolete betaine/GABA:sodium symporter activity (GO:0015376)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (betaine or gamma-aminobutyric acid)(out) + Na+(out) = (betaine or gamma-aminobutyric acid)(in) + Na+(in).
Synonyms: betaine/GABA:sodium symporter activity
Comment: This term was made obsolete because it represents a multifunctional gene product.
chloride:monoatomic cation symporter activity (GO:0015377)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).
Synonyms: cation:chloride cotransporter activity; cation:chloride symporter activity
potassium:proton symporter activity (GO:0015387)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).
Synonyms: potassium:hydrogen symporter activity
obsolete high-affinity secondary active ammonium transmembrane transporter activity (GO:0015398)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
Synonyms: high affinity secondary active ammonium transmembrane transporter activity
Comment: This term was obsoleted because it does not define a specific transport mechanism.
obsolete ABC-type efflux porter activity (GO:0015427)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: ABC-type efflux porter activity
Comment: This term was made obsolete because ABC transporters are a protein family rather than a functional grouping.
ABC-type glutathione S-conjugate transporter activity (GO:0015431)
Namespace: molecular_function
Definition: Catalysis of the reaction: an S-substituted glutathione(in) + ATP + H2O = an S-substituted glutathione(out) + ADP + phosphate + H+.
Synonyms: ATP-dependent glutathione S-conjugate export pump; ATPase-coupled glutathione S-conjugate transmembrane transporter activity; conjugate transporter activity; glutathione S-conjugate-exporting ATPase activity; glutathione S-conjugate-transporting ATPase activity; GS-X pump; MRP1/GS-X pump
ABC-type peptide antigen transporter activity (GO:0015433)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.
Synonyms: ATP-dependent peptide antigen transmembrane transporter activity; ATPase-coupled peptide antigen transmembrane transporter activity; major histocompatibility peptide transporter activity; peptide antigen ABC transporter; peptide antigen transporter activity; peptide antigen-transporting ATPase activity
ABC-type cadmium transporter activity (GO:0015434)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).
Synonyms: ATP-dependent cadmium transmembrane transporter activity; ATPase-coupled cadmium transmembrane transporter activity; cadmium ABC transporter; cadmium-transporting ATPase activity
P-type silver transporter activity (GO:0015445)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) = ADP + phosphate + Ag+(out).
Synonyms: Ag+-exporting ATPase activity; ATP phosphohydrolase (Ag+-exporting); silver exporting ATPase activity; silver transmembrane transporter activity, phosphorylative mechanism; silver-exporting ATPase activity
obsolete autolysin activity (GO:0015466)
Namespace: molecular_function
Definition: OBSOLETE. An agent that can lyse the cell in which it is synthesized.
Synonyms: autolysin activity
Comment: This term was made obsolete because it represents a class of gene products.
obsolete hemaglutinin autotransporter activity (GO:0015476)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.
Comment: The reason for obsoletion is that this term represents a specific substrate of the parent GO:0015474 autotransporter activity.
obsolete hydroxy/aromatic amino acid permease activity (GO:0015507)
Namespace: molecular_function
Definition: OBSOLETE. Permease for hydroxy and aromatic amino acids.
Synonyms: hydroxy/aromatic amino acid permease activity
Comment: This term was made obsolete because it is a redundant grouping term.
glycerol-phosphate:phosphate antiporter activity (GO:0015527)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + phosphate(in) = glycerol phosphate(in) + phosphate(out).
Synonyms: glycerol-phosphate:inorganic phosphate antiporter activity
xanthosine:proton symporter activity (GO:0015537)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).
Synonyms: xanthosine permease activity; xanthosine:hydrogen ion symporter activity
galacturonate transmembrane transporter activity (GO:0015550)
Namespace: molecular_function
Definition: Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
threonine efflux transmembrane transporter activity (GO:0015565)
Namespace: molecular_function
Definition: Enables the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.
Synonyms: threonine efflux permease activity; threonine export protein; threonine export transporter activity
ABC-type D-ribose transporter activity (GO:0015611)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) = ADP + phosphate + D-ribose(in).
Synonyms: D-ribose porter activity; D-ribose-importing ATPase activity
ABC-type D-allose transporter activity (GO:0015615)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) = ADP + phosphate + D-allose(in).
Synonyms: D-allose porter activity; D-allose-importing ATPase activity
ABC-type ferric-enterobactin transporter activity (GO:0015624)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).
Synonyms: ATP-dependent ferric-enterobactin transmembrane transporter activity; ATPase-coupled ferric-enterobactin transmembrane transporter activity; ferric-enterobactin ABC transporter; ferric-enterobactin porter activity; ferric-enterobactin-transporting ATPase activity
toxic substance binding (GO:0015643)
Namespace: molecular_function
Definition: Binding to a toxic substance, a poisonous substance that causes damage to biological systems.
Synonyms: antitoxin activity; lipoprotein antitoxin
vanadium ion transport (GO:0015676)
Namespace: biological_process
Definition: The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
cyanate transport (GO:0015704)
Namespace: biological_process
Definition: The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tellurite transport (GO:0015710)
Namespace: biological_process
Definition: The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
glucuronate transmembrane transport (GO:0015738)
Namespace: biological_process
Definition: The process in which glucuronate is transported across a lipid bilayer, from one side of a membrane to the other.
Synonyms: glucuronate transport
succinate transport (GO:0015744)
Namespace: biological_process
Definition: The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tartrate transmembrane transport (GO:0015745)
Namespace: biological_process
Definition: The process in which tartrate is transported across a lipid bilayer, from one side of a membrane to the other.
Synonyms: tartrate transport
teichoic acid transport (GO:0015777)
Namespace: biological_process
Definition: The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
histidine transport (GO:0015817)
Namespace: biological_process
Definition: The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: L-histidine transport
phenylalanine transport (GO:0015823)
Namespace: biological_process
Definition: The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: L-phenylalanine transport
proline transport (GO:0015824)
Namespace: biological_process
Definition: The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: L-proline transport
tryptophan transport (GO:0015827)
Namespace: biological_process
Definition: The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: L-tryptophan transport
peptide transport (GO:0015833)
Namespace: biological_process
Definition: The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
guanine transport (GO:0015854)
Namespace: biological_process
Definition: The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ATP transport (GO:0015867)
Namespace: biological_process
Definition: The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
acetylcholine transport (GO:0015870)
Namespace: biological_process
Definition: The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
coenzyme A transport (GO:0015880)
Namespace: biological_process
Definition: The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
alkane transport (GO:0015895)
Namespace: biological_process
Definition: The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.
tetracycline transmembrane transport (GO:0015904)
Namespace: biological_process
Definition: The directed movement of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
Synonyms: tetracyclin transport; tetracycline transport
bicyclomycin transmembrane transport (GO:0015905)
Namespace: biological_process
Definition: The directed movement of bicyclomycin across a lipid bilayer, from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
Synonyms: bicyclomycin transport
fucosidase activity (GO:0015928)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.
hexosaminidase activity (GO:0015929)
Namespace: molecular_function
Definition: Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
obsolete symport (GO:0015983)
Namespace: biological_process
Definition: OBSOLETE. The process of solute translocation in which two solutes equilibrate across an osmotic barrier, and the translocation of one solute is coupled to the translocation of the other in the same direction.
Synonyms: symport
Comment: This term was made obsolete because it represents a molecular function rather than a biological process.
obsolete uniport (GO:0015984)
Namespace: biological_process
Definition: OBSOLETE. The process of noncoupled solute translocation or facilitated diffusion.
Synonyms: uniport
Comment: This term was made obsolete because it represents a molecular function rather than a biological process.
maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling (GO:0016058)
Namespace: biological_process
Definition: Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.
Synonyms: maintenance of rhodopsin mediated signaling; maintenance of rhodopsin mediated signalling
obsolete adaptation of rhodopsin mediated signaling (GO:0016062)
Namespace: biological_process
Definition: OBSOLETE. The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.
Synonyms: adaptation of rhodopsin mediated signalling
Comment: This term was obsoleted because it is not mediated by a protein, it's a property of the receptor and of the pathway.
obsolete humoral defense mechanism (sensu Protostomia) (GO:0016065)
Namespace: biological_process
Definition: OBSOLETE. The specific immune response mediated by antibodies. As in, but not restricted to, the taxon Protostomia (Protostomia, ncbi_taxonomy_id:33317).
Synonyms: humoral defence mechanism (sensu Protostomia); humoral defense mechanism (sensu Protostomia)
Comment: This term was made obsolete because antibodies are not found in the taxon Protostomia.
rRNA metabolic process (GO:0016072)
Namespace: biological_process
Definition: The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.
Synonyms: rRNA metabolism
sno(s)RNA metabolic process (GO:0016074)
Namespace: biological_process
Definition: The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.
Synonyms: box C/D sRNA metabolic process; snoRNA metabolism
myostimulatory hormone activity (GO:0016084)
Namespace: molecular_function
Definition: The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.
diterpenoid catabolic process (GO:0016103)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.
Synonyms: diterpene catabolic process; diterpene catabolism; diterpenoid breakdown; diterpenoid catabolism; diterpenoid degradation
terpenoid catabolic process (GO:0016115)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.
Synonyms: terpenoid breakdown; terpenoid catabolism; terpenoid degradation
carotenoid biosynthetic process (GO:0016117)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
Synonyms: carotenoid anabolism; carotenoid biosynthesis; carotenoid formation; carotenoid synthesis
sterol biosynthetic process (GO:0016126)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
Synonyms: sterol anabolism; sterol biosynthesis; sterol formation; sterol synthesis
pyrimidine-nucleoside phosphorylase activity (GO:0016154)
Namespace: molecular_function
Definition: Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.
Synonyms: Py-NPase activity; pyrimidine-nucleoside:phosphate alpha-D-ribosyltransferase activity
beta-amylase activity (GO:0016161)
Namespace: molecular_function
Definition: Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.
Synonyms: 4-alpha-D-glucan maltohydrolase activity; beta amylase activity; glycogenase activity; saccharogen amylase activity
obsolete Mo-molybdopterin oxidoreductase activity (GO:0016164)
Namespace: molecular_function
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: Mo-molybdopterin oxidoreductase activity; molybdopterin oxidoreductase activity
Comment: This term was made obsolete because the differentia from the parent is a gene product feature (specifically, the presence of a molybdopterin cofactor in the protein). It has also never been defined.
glial cell-derived neurotrophic factor receptor activity (GO:0016167)
Namespace: molecular_function
Definition: Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Synonyms: GDNF receptor activity; glial cell line-derived neurotrophic factor receptor activity
snRNA processing (GO:0016180)
Namespace: biological_process
Definition: Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule. The primary function of snRNAs is processing pre-messenger RNA in the nucleus. They have also been shown to aid in the regulation of transcription factors (7SK RNA) or RNA polymerase II (B2 RNA), and maintaining the telomeres.
Synonyms: snRNA maturation; snRNA production
beta-alanine:pyruvate transaminase activity (GO:0016223)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-alanine + 3-oxopropanoate = beta-alanine + pyruvate.
Synonyms: beta-alanine--pyruvate aminotransferase activity; beta-alanine-alpha-alanine transaminase activity; beta-alanine-pyruvate aminotransferase activity; L-alanine:3-oxopropanoate aminotransferase activity; omega-amino acid--pyruvate aminotransferase activity
obsolete tRNA sulfurtransferase activity (GO:0016227)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-cysteine + 'activated' tRNA = L-serine + tRNA containing a thionucleotide.
Synonyms: L-cysteine:tRNA sulfurtransferase activity; ribonucleate sulfurtransferase activity; RNA sulfurtransferase activity; transfer ribonucleate sulfurtransferase activity; transfer RNA sulfurtransferase activity; transfer RNA thiolase activity; tRNA sulfurtransferase activity; tRNA sulphurtransferase activity
Comment: This term was made obsolete because tRNA thionucleotide formation is a multistep process; there is no single reaction in which cysteine reacts with an activated tRNA directly
steroid dehydrogenase activity (GO:0016229)
Namespace: molecular_function
Definition: Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
beta-N-acetylglucosaminidase activity (GO:0016231)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.
obsolete core 1 and core 2 O-glycan biosynthetic process (GO:0016267)
Namespace: biological_process
Definition: OBSOLETE. The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc, and ultimately forming the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.
Synonyms: core 1 O-glycan biosynthesis; core 2 O-glycan biosynthesis; mucin type O-glycosylation; O-glycan processing, core 1; O-glycan processing, core 2
Comment: This term was obsoleted because it represents a specific GalNAcylation pathway, and these are too diverse to fully represent in GO.
arginine N-methyltransferase activity (GO:0016273)
Namespace: molecular_function
Definition: Enables the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.
phosphorylation (GO:0016310)
Namespace: biological_process
Definition: The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
establishment or maintenance of polarity of follicular epithelium (GO:0016334)
Namespace: biological_process
Definition: Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.
obsolete other collagen (GO:0016341)
Namespace: cellular_component
Definition: OBSOLETE. (Was not defined before being made obsolete).
Synonyms: other collagen
Comment: This term was made obsolete because it is a redundant grouping term.