LiteFold/GO huggingface dataset:
obsolete negative regulation of cytolysis by symbiont of host cells (GO:0001899)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: down regulation by symbiont of cytolysis of host cells; down-regulation by symbiont of cytolysis of host cells; downregulation by symbiont of cytolysis of host cells; inhibition by symbiont of cytolysis of host cells; negative regulation by symbiont of cytolysis of host cells
Comment: This term was obsoleted because it has been used inconsistently.
B-1 B cell differentiation (GO:0001923)
Namespace: biological_process
Definition: The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
Synonyms: B-1 B cell development; B-1 B lymphocyte differentiation; B-1 B-cell differentiation; B-1 B-lymphocyte differentiation
negative regulation of exocyst assembly (GO:0001929)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.
Synonyms: down regulation of exocyst assembly; down-regulation of exocyst assembly; downregulation of exocyst assembly; inhibition of exocyst assembly
regulation of endothelial cell proliferation (GO:0001936)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.
female pronucleus (GO:0001939)
Namespace: cellular_component
Definition: The pronucleus originating from the ovum that is being fertilized.
regulation of cell-matrix adhesion (GO:0001952)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
endochondral ossification (GO:0001958)
Namespace: biological_process
Definition: Replacement ossification wherein bone tissue replaces cartilage.
startle response (GO:0001964)
Namespace: biological_process
Definition: An action or movement due to the application of a sudden unexpected stimulus.
fibronectin binding (GO:0001968)
Namespace: molecular_function
Definition: Binding to a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
regulation of activation of membrane attack complex (GO:0001969)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
Synonyms: regulation of activation of MAC; regulation of activation of TCC; regulation of activation of terminal complement complex; regulation of activation of the terminal complement cascade; regulation of MAC assembly; regulation of MAC formation; regulation of membrane attack complex assembly; regulation of membrane attack complex formation
regulation of systemic arterial blood pressure by ischemic conditions (GO:0001980)
Namespace: biological_process
Definition: The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.
Synonyms: CNS ischemic response; ischemic control of blood pressure; ischemic regulation of systemic arterial blood pressure
positive regulation of the force of heart contraction by epinephrine-norepinephrine (GO:0001997)
Namespace: biological_process
Definition: Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.
Synonyms: increased force of heart contraction by adrenaline-noradrenaline; increased force of heart contraction by epinephrine-norepinephrine; increased inotropy by epinephrine-norepinephrine; increased strength of cardiac contraction by epinephrine-norepinephrine; positive regulation of heart contraction by adrenaline-noradrenaline; positive regulation of heart contraction by epinephrine-norepinephrine
obsolete secretion of vasopressin involved in fast regulation of systemic arterial blood pressure (GO:0002004)
Namespace: biological_process
Definition: OBSOLETE. The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.
Synonyms: secretion of vasopressin during fast control of blood pressure; secretion of vasopressin during fast regulation of systemic arterial blood pressure
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
morphogenesis of an epithelial sheet (GO:0002011)
Namespace: biological_process
Definition: The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
response to dietary excess (GO:0002021)
Namespace: biological_process
Definition: The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
G protein-coupled receptor internalization (GO:0002031)
Namespace: biological_process
Definition: The process that results in the uptake of a G protein-coupled receptor into an endocytic vesicle.
Synonyms: G-protein coupled receptor internalization
regulation of L-glutamate import across plasma membrane (GO:0002036)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of L-glutamate import into a cell.
Synonyms: regulation of L-glutamate import; regulation of L-glutamate transport; regulation of L-glutamate uptake
obsolete pyoverdine metabolic process (GO:0002048)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving the siderochrome pyoverdine.
Synonyms: pyoverdine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
pyoverdine catabolic process (GO:0002050)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.
osteoblast fate commitment (GO:0002051)
Namespace: biological_process
Definition: The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
chondrocyte development (GO:0002063)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
osteoblast development (GO:0002076)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.
regulation of receptor internalization (GO:0002090)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of receptor internalization.
positive regulation of receptor internalization (GO:0002092)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of receptor internalization.
Synonyms: activation of receptor internalization; stimulation of receptor internalization; up regulation of receptor internalization; up-regulation of receptor internalization; upregulation of receptor internalization
aggressive behavior (GO:0002118)
Namespace: biological_process
Definition: A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.
Synonyms: aggression
stereocilia tip link (GO:0002140)
Namespace: cellular_component
Definition: A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.
regulation of thyroid hormone receptor signaling pathway (GO:0002155)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.
Synonyms: regulation of thyroid hormone mediated signaling pathway; regulation of thyroid hormone mediated signalling pathway
positive regulation of thyroid hormone receptor signaling pathway (GO:0002157)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.
Synonyms: positive regulation of thyroid hormone mediated signaling pathway; positive regulation of thyroid hormone mediated signalling pathway
desmosome assembly (GO:0002159)
Namespace: biological_process
Definition: A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
Comment: Desmosomes link two cells together; hemidesmosomes attach one cell to the extracellular matrix.
male germ cell proliferation (GO:0002176)
Namespace: biological_process
Definition: The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.
cytoplasmic translational elongation (GO:0002182)
Namespace: biological_process
Definition: The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
obsolete 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis (GO:0002195)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.
Comment: This term was obsoleted because this is a molecular function.
somatic diversification of immune receptors (GO:0002200)
Namespace: biological_process
Definition: The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
Comment: Note that this process covers somatic recombination, gene conversion, hypermutation, N-region addition, and alternate splicing processes of immune receptor diversification.
somatic diversification of immunoglobulins involved in immune response (GO:0002208)
Namespace: biological_process
Definition: The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.
Synonyms: somatic diversification of antibodies during immune response; somatic diversification of immunoglobulins during immune response
behavioral defense response to nematode (GO:0002212)
Namespace: biological_process
Definition: A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
Synonyms: behavioural defense response to nematode
pattern recognition receptor signaling pathway (GO:0002221)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to a pattern recognition receptor (PRR), and ending with the regulation of a downstream cellular process, e.g. transcription. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
Synonyms: pathogen receptor signaling pathway; pathogen receptor signalling pathway; PRR signaling pathway
toll-like receptor signaling pathway (GO:0002224)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to a toll-like receptor of a target cell. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate an innate immune response.
Synonyms: TLR signaling pathway; toll-like receptor signalling pathway
Comment: Note that the vertebrate toll-like receptors, unlike the Drosophila Toll molecule, directly bind their ligands. The Drosophila Toll molecule requires the Sptzle factor to bind microbial ligands and then the receptor in order to initiate innate immune responses.
response to molecule of fungal origin (GO:0002238)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
Synonyms: response to fungus associated molecule
response to molecule of oomycetes origin (GO:0002240)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.
Synonyms: response to oomycetes associated molecule
immune effector process (GO:0002252)
Namespace: biological_process
Definition: Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation.
myeloid dendritic cell activation involved in immune response (GO:0002277)
Namespace: biological_process
Definition: The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms: myeloid dendritic cell activation during immune response
neutrophil activation involved in immune response (GO:0002283)
Namespace: biological_process
Definition: The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms: neutrophil activation during immune response
T cell activation involved in immune response (GO:0002286)
Namespace: biological_process
Definition: The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
Synonyms: T cell activation during immune response; T lymphocyte activation during immune response; T-cell activation during immune response; T-lymphocyte activation during immune response
CD8-positive, gamma-delta intraepithelial T cell differentiation (GO:0002305)
Namespace: biological_process
Definition: The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
Synonyms: CD8-positive, gamma-delta intraepithelial T cell development; CD8-positive, gamma-delta intraepithelial T lymphocyte differentiation; CD8-positive, gamma-delta intraepithelial T-cell differentiation; CD8-positive, gamma-delta intraepithelial T-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
obsolete natural killer cell differentiation involved in immune response (GO:0002325)
Namespace: biological_process
Definition: OBSOLETE. The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.
Synonyms: natural killer cell development involved in immune response; natural killer cell differentiation during immune response; NK cell differentiation during immune response
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
pro-B cell differentiation (GO:0002328)
Namespace: biological_process
Definition: The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
Synonyms: pro-B cell development; pro-B lymphocyte differentiation
central B cell anergy (GO:0002341)
Namespace: biological_process
Definition: Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.
Synonyms: central B lymphocyte anergy; central B-cell anergy; central B-lymphocyte anergy
B cell positive selection (GO:0002346)
Namespace: biological_process
Definition: Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.
Synonyms: B lymphocyte positive selection; B-cell positive selection; B-lymphocyte positive selection
response to tumor cell (GO:0002347)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
central B cell positive selection (GO:0002348)
Namespace: biological_process
Definition: Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
Synonyms: central B lymphocyte positive selection; central B-cell positive selection; central B-lymphocyte positive selection
B cell homeostatic proliferation (GO:0002358)
Namespace: biological_process
Definition: The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
Synonyms: B lymphocyte homeostatic proliferation; B-cell homeostatic proliferation; B-lymphocyte homeostatic proliferation
B-1 B cell proliferation (GO:0002359)
Namespace: biological_process
Definition: The expansion of a B-1 B cell by cell division. Follows B cell activation.
Synonyms: B-1 B lymphocyte proliferation; B-1 B-cell proliferation; B-1 B-lymphocyte proliferation
leukocyte activation involved in immune response (GO:0002366)
Namespace: biological_process
Definition: A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
Synonyms: immune cell activation during immune response; leucocyte activation during immune response; leukocyte activation during immune response
dendritic cell cytokine production (GO:0002371)
Namespace: biological_process
Definition: Any process that contributes to cytokine production by a dendritic cell.
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
immune response to tumor cell (GO:0002418)
Namespace: biological_process
Definition: An immune system process that functions in the response of an organism to a tumor cell.
Fc receptor mediated stimulatory signaling pathway (GO:0002431)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms: Fc receptor mediated stimulatory signalling pathway; Fc-receptor mediated stimulatory signaling pathway
histamine secretion involved in inflammatory response (GO:0002441)
Namespace: biological_process
Definition: The regulated release of histamine by a cell as part of an inflammatory response.
Synonyms: histamine secretion involved in acute inflammatory response
germinal center formation (GO:0002467)
Namespace: biological_process
Definition: The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (GO:0002486)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
Synonyms: endogenous peptide antigen processing and presentation via MHC class I via ER pathway, TAP-independent; TAP-independent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway; TAP-independent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
antigen processing and presentation of endogenous peptide antigen via MHC class II (GO:0002491)
Namespace: biological_process
Definition: The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
Synonyms: endogenous peptide antigen processing and presentation via MHC class II
obsolete regulation of systemic arterial blood pressure involved in acute-phase response (GO:0002530)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
Synonyms: blood pressure regulation during acute phase response; regulation of systemic arterial blood pressure during acute phase response
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete regulation of heart contraction involved in acute-phase response (GO:0002531)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
Synonyms: regulation of cardiac contraction during acute phase response; regulation of heart contraction during acute phase response
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.