LiteFold/GO huggingface dataset:
lipoyl(octanoyl) transferase activity (GO:0033819)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].
Synonyms: lipoate/octanoate transferase activity; lipoyl (octanoyl)-acyl carrier protein:protein transferase activity; lipoyl (octanoyl)-acyl-carrier-protein-protein N-lipoyltransferase activity; octanoyl transferase activity (acting on glycine-cleavage complex H protein); octanoyl-acyl carrier protein-protein N-octanoyltransferase activity; octanoyl-acyl-carrier-protein-protein N-octanoyltransferase activity; octanoyl-acyl-carrier-protein:protein N-octanoyltransferase activity
high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity (GO:0033827)
Namespace: molecular_function
Definition: Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.
Synonyms: acetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity; UDP-GlcNAc:oligosaccharide beta-N-acetylglucosaminyltransferase activity; UDP-N-acetyl-D-glucosamine:high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity; uridine diphosphoacetylglucosamine-oligosaccharide acetylglucosaminyltransferase activity
nicotianamine:2-oxoglutarate transaminase activity (GO:0033855)
Namespace: molecular_function
Definition: Catalysis of the reaction: nicotianamine + 2-oxoglutarate = 3''-deamino-3''-oxonicotianamine + L-glutamate.
Synonyms: NAAT; NAAT-I; NAAT-II; NAAT-III; nicotianamine aminotransferase activity; nicotianamine transaminase activity; nicotianamine:2-oxoglutarate aminotransferase activity
obsolete regulation of NAD(P)H oxidase activity (GO:0033860)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the activity of the enzyme NAD(P)H oxidase.
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
ribose 1,5-bisphosphate phosphokinase activity (GO:0033863)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H+.
Synonyms: ATP:ribose-1,5-bisphosphate phosphotransferase activity; PhnN; ribose 1,5-bisphosphokinase activity
nucleoside bisphosphate metabolic process (GO:0033865)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
Synonyms: nucleoside bisphosphate metabolism
obsolete heparan sulfate 3-sulfotransferase 2 activity (GO:0033871)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-(heparan sulfate)(n) = 3-sulfo-alpha-D-glucosaminyl-(heparan sulfate)(n) + adenosine 3',5'-bisphosphate + H+. Modifies selected glucosamine residues preceded by GlcA2S.
Synonyms: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity; heparin-glucosamine 3-sulfotransferase 2 activity
Comment: The reason for obsoletion is that the term represents the same [heparan sulfate]-glucosamine 3-sulfotransferase activity as GO:0008467.
chondro-6-sulfatase activity (GO:0033888)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.
Synonyms: 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-6-sulfate 6-sulfohydrolase activity
ribonuclease D activity (GO:0033890)
Namespace: molecular_function
Definition: Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
Synonyms: RNase D activity
oligoxyloglucan beta-glycosidase activity (GO:0033935)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.
Synonyms: isoprimeverose-producing oligoxyloglucan hydrolase activity; oligoxyloglucan hydrolase activity; oligoxyloglucan xyloglucohydrolase activity
acidocalcisome lumen (GO:0033985)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of an acidocalcisome.
chondroitin B lyase activity (GO:0033999)
Namespace: molecular_function
Definition: Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.
Synonyms: ChnB; chonB; chondroitinase B activity; dermatan sulfate lyase activity
germacrene-A synthase activity (GO:0034005)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
Synonyms: (+)-(10R)-germacrene A synthase activity; (+)-germacrene A synthase activity; 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity; 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity; GAS; germacrene A synthase activity
neoxanthin synthase activity (GO:0034020)
Namespace: molecular_function
Definition: Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.
Synonyms: NSY; violaxanthin-neoxanthin isomerase (epoxide-opening) activity
5-(carboxyamino)imidazole ribonucleotide synthase activity (GO:0034028)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H+ + phosphate.
Synonyms: 5-amino-1-(5-phospho-D-ribosyl)imidazole:carbon-dioxide ligase (ADP-forming) activity; N5-CAIR synthetase activity; N5-carboxyaminoimidazole ribonucleotide synthetase activity; PurK
purine nucleoside bisphosphate metabolic process (GO:0034032)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
Synonyms: purine nucleoside bisphosphate metabolism
symbiont-induced defense-related programmed cell death (GO:0034050)
Namespace: biological_process
Definition: Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules.
Synonyms: host programmed cell death induced by symbiont; programmed cell death induced by symbiont
Comment: Note that this term is to be used to annotate gene products in the host, not the symbiont. To annotate gene products in the symbiont that induce programmed cell death in the host, consider the biological process term 'symbiont-mediated activation of host programmed cell death' ; GO:0052042'.
aminoglycoside nucleotidyltransferase activity (GO:0034068)
Namespace: molecular_function
Definition: Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.
Synonyms: aminoglycoside adenylyltransferase activity; streptomycin adenylate synthetase activity; streptomycin adenyltransferase activity; streptomycin adenylylase activity; streptomycin adenylyltransferase activity; streptomycin-spectinomycin adenylyltransferase activity
establishment of sister chromatid cohesion (GO:0034085)
Namespace: biological_process
Definition: The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.
maintenance of sister chromatid cohesion (GO:0034086)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.
regulation of maintenance of meiotic sister chromatid cohesion (GO:0034094)
Namespace: biological_process
Definition: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
response to cytokine (GO:0034097)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
Synonyms: response to cytokine stimulus
negative regulation of tissue remodeling (GO:0034104)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.
Synonyms: negative regulation of tissue remodelling
negative regulation of erythrocyte clearance (GO:0034107)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.
Synonyms: negative regulation of neocytolysis; negative regulation of RBC clearance; negative regulation of red blood cell clearance
negative regulation of toll-like receptor signaling pathway (GO:0034122)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
Synonyms: negative regulation of TLR signaling pathway; negative regulation of toll-like receptor signalling pathway
regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034124)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
Synonyms: regulation ofMyD88-dependent TLR signaling pathway; regulation ofMyD88-dependent toll-like receptor signalling pathway
regulation of toll-like receptor 1 signaling pathway (GO:0034131)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
Synonyms: regulation of TLR1 signaling pathway; regulation of toll-like receptor 1 signalling pathway
regulation of toll-like receptor 10 signaling pathway (GO:0034167)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
Synonyms: regulation of TLR10 signaling pathway; regulation of toll-like receptor 10 signalling pathway
toll-like receptor 11 signaling pathway (GO:0034170)
Namespace: biological_process
Definition: The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 11.
Synonyms: TLR11 signaling pathway; toll-like receptor 11 signalling pathway
regulation of maintenance of mitotic sister chromatid cohesion (GO:0034182)
Namespace: biological_process
Definition: Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
D-galactonate catabolic process (GO:0034194)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.
Synonyms: D-galactonate breakdown; D-galactonate catabolism; D-galactonate degradation
amyloid-beta formation (GO:0034205)
Namespace: biological_process
Definition: The generation of amyloid-beta by cleavage of the amyloid precursor protein (APP).
Synonyms: beta-amyloid formation; beta-amyloid polypeptide formation from amyloid precursor protein; beta-amyloid polypeptide formation from APP
Comment: Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because amyloid-beta can only be formed by the proteolysis of a larger molecule (see term definition). The word 'formation' is therefore used in place of biosynthesis. Also, note that this term refers to the production of the amyloid-beta polypeptide from the amyloid precursor protein (APP), and should be used to annotate e.g. secretases that cleave APP to form amyloid-beta. To annotate gene products involved in the formation of amyloid fibrils, please consider 'amyloid fibril formation' (GO:1990000).
enhanceosome (GO:0034206)
Namespace: cellular_component
Definition: A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.
obsolete steroid deacetylation (GO:0034208)
Namespace: biological_process
Definition: OBSOLETE. The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
Comment: This term was obsoleted because it represents a molecular function.
obsolete ascospore wall chitin catabolic process (GO:0034232)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
Synonyms: ascospore wall chitin breakdown; ascospore wall chitin catabolism; ascospore wall chitin degradation
Comment: The reason for obsoletion is that this^Cerm is mixing biological process and cellular component.
regulation of macrophage fusion (GO:0034239)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of macrophage fusion.
negative regulation of GTPase activity (GO:0034260)
Namespace: biological_process
Definition: Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
Synonyms: down regulation of GTPase activity; down regulation of Rab GTPase activity; down regulation of Ras GTPase activity; down regulation of regulation of Ran GTPase activity; down regulation of Rho GTPase activity; down-regulation of GTPase activity; down-regulation of Rab GTPase activity; down-regulation of Ras GTPase activity; down-regulation of regulation of Ran GTPase activity; down-regulation of Rho GTPase activity; downregulation of GTPase activity; downregulation of Rab GTPase activity; downregulation of Ras GTPase activity; downregulation of regulation of Ran GTPase activity; downregulation of Rho GTPase activity; inhibition of GTPase activity; inhibition of Rab GTPase activity; inhibition of Ras GTPase activity; inhibition of regulation of Ran GTPase activity; inhibition of Rho GTPase activity; negative regulation of guanosinetriphosphatase activity; negative regulation of Rab GTPase activity; negative regulation of Ran GTPase activity; negative regulation of Ras GTPase activity; negative regulation of Rho GTPase activity
Comment: An example of this is P2xA in Dictyostelium (UniProt symbol Q86JM7) in PMID:24335649.
positive regulation of autophagy in response to ER overload (GO:0034263)
Namespace: biological_process
Definition: The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.
Synonyms: autophagy in response to endoplasmic reticulum overload; autophagy in response to ER stress
ent-pimara-8(14),15-diene synthase activity (GO:0034282)
Namespace: molecular_function
Definition: Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.
Synonyms: ent-copalyl-diphosphate diphosphate-lyase [ent-pimara-8(14),15-diene-forming] activity; ent-pimaradiene synthase activity
response to monosaccharide (GO:0034284)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
Synonyms: response to monosaccharide stimulus
detection of monosaccharide stimulus (GO:0034287)
Namespace: biological_process
Definition: The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.
Synonyms: perception of monosaccharide stimulus
arthrospore formation (GO:0034298)
Namespace: biological_process
Definition: The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.
Synonyms: arthroconidium formation
regulation of sexual sporulation (GO:0034306)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.
Synonyms: MAPKKK cascade during sporulation; regulation of meiotic spore formation; regulation of meiotic sporulation; regulation of sexual spore formation
regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
obsolete alcohol O-butanoyltransferase activity (GO:0034319)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.
Comment: This term was obsoleted because it represents a specific substrate of alcohol O-acetyltransferase activity ; GO:0004026.
obsolete alcohol O-octanoyltransferase activity (GO:0034321)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester.
Comment: This term was obsoleted because it represents a specific substrate of alcohol O-acetyltransferase activity ; GO:0004026.
obsolete O-hexanoyltransferase activity (GO:0034324)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule.
Comment: The reason for obsoletion is that there is no evidence that this function exists.
DNA negative supercoiling activity (GO:0034335)
Namespace: molecular_function
Definition: Catalytic introduction of negative supercoils into a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.
Synonyms: DNA gyrase activity; DNA-gyrase activity
Comment: Note that this term was reinstated from obsolete.
misfolded RNA binding (GO:0034336)
Namespace: molecular_function
Definition: Binding to an RNA molecule that has assumed an incorrect conformation.
Synonyms: RNA chaperone
type III interferon receptor activity (GO:0034348)
Namespace: molecular_function
Definition: Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.
Synonyms: interferon-lambda receptor activity
Comment: Note that IL-28A, IL-28B, and IL-29 are types of interferon-lambda.
NAD+ biosynthetic process via the salvage pathway (GO:0034355)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide (NAD+) from vitamin B3 derivatives (including nicotinic acid (NA) and nicotinamide (NAM)), beta-nicotinamide D-ribonucleotide (NMN), nicotinamide riboside (NR) or nicotinate riboside (NAR), without de novo synthesis.
Synonyms: NAD biosynthetic process via the salvage pathway; NAD salvage; NAD salvage pathway
plasma lipoprotein particle (GO:0034358)
Namespace: cellular_component
Definition: A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
spherical high-density lipoprotein particle (GO:0034366)
Namespace: cellular_component
Definition: A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
Synonyms: mature HDL; mature high-density lipoprotein particle; spherical HDL
chylomicron remodeling (GO:0034371)
Namespace: biological_process
Definition: The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
Synonyms: chylomicron remnant formation; chylomicron remodelling
plasma lipoprotein particle clearance (GO:0034381)
Namespace: biological_process
Definition: The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms: lipoprotein particle clearance
smooth muscle cell apoptotic process (GO:0034390)
Namespace: biological_process
Definition: Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.
Synonyms: apoptosis of smooth muscle cells; programmed cell death of smooth muscle cells by apoptosis; programmed cell death, smooth muscle cells; SMC apoptosis; smooth muscle cell apoptosis; smooth muscle cell programmed cell death by apoptosis
ascospore wall beta-glucan metabolic process (GO:0034408)
Namespace: biological_process
Definition: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
Synonyms: ascospore wall beta-glucan metabolism
cell wall (1->3)-beta-D-glucan biosynthetic process (GO:0034411)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
Synonyms: cell wall 1,3-beta-D-glucan biosynthetic process; cell wall 1,3-beta-glucan anabolism; cell wall 1,3-beta-glucan biosynthesis; cell wall 1,3-beta-glucan biosynthetic process; cell wall 1,3-beta-glucan formation; cell wall 1,3-beta-glucan synthesis; cell wall beta-1,3-glucan anabolism; cell wall beta-1,3-glucan biosynthesis; cell wall beta-1,3-glucan biosynthetic process; cell wall beta-1,3-glucan formation; cell wall beta-1,3-glucan synthesis
obsolete tRNA 3'-trailer cleavage, endonucleolytic (GO:0034414)
Namespace: biological_process
Definition: OBSOLETE. Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
Synonyms: endonucleolytic tRNA 3'-end cleavage; endonucleolytic tRNA 3'-trailer cleavage; tRNA 3'-end cleavage, endonucleolytic
Comment: The reason for obsoletion is that the term represents a molecular function.