LiteFold/GO huggingface dataset:
regulation of lipid catabolic process (GO:0050994)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
Synonyms: regulation of lipid breakdown; regulation of lipid catabolism; regulation of lipid degradation
nitric-oxide synthase binding (GO:0050998)
Namespace: molecular_function
Definition: Binding to nitric-oxide synthase.
Synonyms: NOS binding
regulation of nitric-oxide synthase activity (GO:0050999)
Namespace: biological_process
Definition: Any process that modulates the activity of the enzyme nitric-oxide synthase.
Synonyms: nitric-oxide synthase regulator; NOS regulator; regulation of NOS activity
positive regulation of nitric-oxide synthase activity (GO:0051000)
Namespace: biological_process
Definition: Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
Synonyms: activation of nitric-oxide synthase activity; nitric-oxide synthase activator; NOS activator; positive regulation of NOS activity; stimulation of nitric-oxide synthase activity; up regulation of nitric-oxide synthase activity; up-regulation of nitric-oxide synthase activity; upregulation of nitric-oxide synthase activity
ligase activity, forming nitrogen-metal bonds (GO:0051002)
Namespace: molecular_function
Definition: Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
microtubule sliding (GO:0051012)
Namespace: biological_process
Definition: The movement of one microtubule along another microtubule.
Synonyms: microtubule translocation
galactomannan biosynthetic process (GO:0051070)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.
Synonyms: galactomannan anabolism; galactomannan biosynthesis; galactomannan formation; galactomannan synthesis
'de novo' cotranslational protein folding (GO:0051083)
Namespace: biological_process
Definition: The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.
Synonyms: 'de novo' co-translational protein folding; multidomain protein assembly; nascent polypeptide association
obsolete regulation of helicase activity (GO:0051095)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of helicase activity.
Comment: This term was obsoleted because it represents a molecular function.
positive regulation of NK T cell activation (GO:0051135)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.
Synonyms: activation of NK T cell activation; positive regulation of natural killer T cell activation; positive regulation of natural T cell activation; positive regulation of NK T lymphocyte activation; positive regulation of NK T-cell activation; positive regulation of NK T-lymphocyte activation; positive regulation of NKT cell activation; positive regulation of NT cell activation; stimulation of NK T cell activation; up regulation of NK T cell activation; up-regulation of NK T cell activation; upregulation of NK T cell activation
negative regulation of NK T cell proliferation (GO:0051141)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.
Synonyms: down regulation of NK T cell proliferation; down-regulation of NK T cell proliferation; downregulation of NK T cell proliferation; inhibition of NK T cell proliferation; negative regulation of natural killer T cell proliferation; negative regulation of natural T cell proliferation; negative regulation of NK T lymphocyte proliferation; negative regulation of NK T-cell proliferation; negative regulation of NK T-lymphocyte proliferation; negative regulation of NKT cell proliferation; negative regulation of NT cell proliferation
1,2-propanediol catabolic process (GO:0051144)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.
Synonyms: 1,2-dihydroxypropane catabolic process; 1,2-dihydroxypropane catabolism; propanediol breakdown; propanediol catabolic process; propanediol catabolism; propanediol degradation; propylene glycol catabolic process; propylene glycol catabolism
negative regulation of smooth muscle cell differentiation (GO:0051151)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
Synonyms: down regulation of smooth muscle cell differentiation; down-regulation of smooth muscle cell differentiation; downregulation of smooth muscle cell differentiation; inhibition of smooth muscle cell differentiation
positive regulation of striated muscle cell differentiation (GO:0051155)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.
Synonyms: activation of striated muscle cell differentiation; stimulation of striated muscle cell differentiation; up regulation of striated muscle cell differentiation; up-regulation of striated muscle cell differentiation; upregulation of striated muscle cell differentiation
glucose 6-phosphate metabolic process (GO:0051156)
Namespace: biological_process
Definition: The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
Synonyms: glucose 6-phosphate metabolism; glucose 6-phosphate utilization
obsolete arabitol metabolic process (GO:0051161)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
Synonyms: arabitol metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
obsolete 2,5-dihydroxypyridine catabolic process (GO:0051166)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.
Synonyms: 2,5-dihydroxypyridine breakdown; 2,5-dihydroxypyridine catabolism; 2,5-dihydroxypyridine degradation; pyridine-2,5-diol catabolic process
Comment: This term was obsoleted because it represents an intermediate in nicotinate catabolic process ; GO:1901848.
import into nucleus (GO:0051170)
Namespace: biological_process
Definition: The directed movement of substances into the nucleus.
Synonyms: nuclear import; nuclear translocation
obsolete coenzyme transmembrane transporter activity (GO:0051185)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a coenzyme from one side of a membrane to the other. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
Synonyms: coenzyme transporter activity
Comment: 1. Making inferences in GO about compounds based on the coenzyme role curated by ChEBI creates relationships that are not always true which violates ontological principles for GO; therefore we will cease making these inferences. 2. It is not meaningful to group transport processes that are not all chemically related by the fact that they may be used as a coenzyme.
protein insertion into mitochondrial membrane (GO:0051204)
Namespace: biological_process
Definition: The process that results in the incorporation of a protein into a mitochondrial membrane.
Synonyms: integral mitochondrial membrane protein localization; integral mitochondrial membrane protein positioning; localization of protein in mitochondrial membrane; positioning of protein in mitochondrial membrane; protein insertion into mitochondrion membrane; protein-mitochondrial membrane insertion; protein-mitochondrion membrane insertion
positive regulation of RNA metabolic process (GO:0051254)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
Synonyms: activation of RNA metabolic process; positive regulation of RNA metabolism; stimulation of RNA metabolic process; up regulation of RNA metabolic process; up-regulation of RNA metabolic process; upregulation of RNA metabolic process
meiotic spindle midzone assembly (GO:0051257)
Namespace: biological_process
Definition: The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.
Synonyms: meiotic spindle midzone biogenesis; meiotic spindle midzone biosynthesis; meiotic spindle midzone formation; spindle midzone assembly involved in meiosis; spindle midzone biogenesis involved in meiosis; spindle midzone biosynthesis involved in meiosis; spindle midzone formation involved in meiosis
beta-glucan catabolic process (GO:0051275)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of beta-glucans.
Synonyms: beta-glucan breakdown; beta-glucan catabolism; beta-glucan degradation
obsolete regulation of sequestering of calcium ion (GO:0051282)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
Synonyms: regulation of calcium ion (Ca2+) retention; regulation of calcium ion (Ca2+) sequestering; regulation of calcium ion (Ca2+) sequestration; regulation of calcium ion (Ca2+) storage; regulation of retention of calcium ion (Ca2+); regulation of sequestering of calcium ion (Ca2+); regulation of sequestration of calcium ion (Ca2+); regulation of storage of calcium ion (Ca2+)
Comment: The reason for obsoletion is that this term represents a molecular function and not a real GO process.
protein heterooligomerization (GO:0051291)
Namespace: biological_process
Definition: The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
Synonyms: protein heterooligomer assembly; protein heterooligomer biosynthesis; protein heterooligomer biosynthetic process; protein heterooligomer formation
nuclear pore complex assembly (GO:0051292)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.
Synonyms: NPC assembly; nuclear pore assembly; nuclear pore biogenesis; nuclear pore biosynthesis; nuclear pore complex biogenesis; nuclear pore complex biosynthesis; nuclear pore complex formation; nuclear pore formation
establishment of meiotic spindle localization (GO:0051295)
Namespace: biological_process
Definition: The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.
Synonyms: establishment of meiotic spindle localisation; meiotic spindle positioning; spindle positioning during meiosis; spindle positioning involved in meiotic cell cycle
meiotic chromosome separation (GO:0051307)
Namespace: biological_process
Definition: The process in which chromosomes are physically detached from each other during meiosis.
Synonyms: chromosome separation during meiosis; meiotic chromosome resolution
meiotic metaphase chromosome alignment (GO:0051311)
Namespace: biological_process
Definition: A chromosome localization process whereby chromosomes are positioned in a specific order and orientation at the metaphase plate (spindle equator), during meiotic chromosome segregation. This alignment ensures that each daughter cell will receive the correct number of chromosomes during cell division.
Synonyms: metaphase plate congression during meiosis
regulation of transferase activity (GO:0051338)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
Synonyms: transferase regulator
Comment: This term is useful for grouping, but is too general for manual annotation. Please use a child term instead.
obsolete positive regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051343)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
Synonyms: 3',5' cyclic nucleotide phosphodiesterase activator; 3',5'-cyclic-AMP phosphodiesterase activator; activation of cyclic nucleotide phosphodiesterase activity; cAMP phosphodiesterase activator; phosphodiesterase activator; positive regulation of 3',5' cyclic nucleotide phosphodiesterase activity; positive regulation of 3',5'-cyclic-AMP phosphodiesterase activity; positive regulation of cAMP phosphodiesterase activity; positive regulation of cGMP phosphodiesterase activity; positive regulation of cyclic nucleotide phosphodiesterase activity; stimulation of cyclic nucleotide phosphodiesterase activity; up regulation of cyclic nucleotide phosphodiesterase activity; up-regulation of cyclic nucleotide phosphodiesterase activity; upregulation of cyclic nucleotide phosphodiesterase activity
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
negative regulation of hydrolase activity (GO:0051346)
Namespace: biological_process
Definition: Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
Synonyms: down regulation of hydrolase activity; down-regulation of hydrolase activity; downregulation of hydrolase activity; hydrolase inhibitor; inhibition of hydrolase activity
obsolete peptide cross-linking via L-lysine 5-imidazolinone glycine (GO:0051361)
Namespace: biological_process
Definition: OBSOLETE. The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
Synonyms: biosynthesis of protein-protein cross-link via L-lysine 5-imidazolinone glycine; biosynthetic process of protein-protein cross-link via L-lysine 5-imidazolinone glycine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine (GO:0051362)
Namespace: biological_process
Definition: OBSOLETE. The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species.
Synonyms: biosynthesis of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine; biosynthetic process of protein-protein cross-link via 2-tetrahydropyridinyl-5-imidazolinone glycine
Comment: This term was obsoleted because it represents a molecular function; however the enzyme responsible for this reaction has not been defined in RESID.
obsolete peptidyl-serine decanoylation (GO:0051367)
Namespace: biological_process
Definition: OBSOLETE. The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.
Comment: This term was obsoleted because it represents a molecular function.
serotonin binding (GO:0051378)
Namespace: molecular_function
Definition: Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms: 5-hydroxytryptamine binding
kinetochore assembly (GO:0051382)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
Synonyms: centromere and kinetochore complex maturation; centromere/kinetochore complex maturation; chromosome-kinetochore attachment; kinetochore formation; NMS complex assembly
obsolete N-terminal arginine aminopeptidase activity (GO:0051399)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of an arginine residue from the N-terminal of an oligopeptide or polypeptide chain.
Synonyms: arginine aminopeptidase activity; argininyl aminopeptidase activity; N-terminal arginine aminopeptidase activity
Comment: This term was made obsolete because it represents a gene product.
CH domain binding (GO:0051401)
Namespace: molecular_function
Definition: Binding to a calponin homology protein domain, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.
Synonyms: calponin homology domain binding
microtubule nucleation by interphase microtubule organizing center (GO:0051415)
Namespace: biological_process
Definition: The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.
Synonyms: IMTOC-mediated microtubule nucleation during interphase; interphase microtubule nucleation by interphase microtubule organising centre; interphase microtubule nucleation by interphase microtubule organizing center; interphase microtubule organizing center-mediated microtubule nucleation during interphase; microtubule nucleation during interphase by IMTOC; microtubule nucleation during interphase by interphase microtubule organizing center
regulation of intracellular pH (GO:0051453)
Namespace: biological_process
Definition: Any process that modulates the internal pH of a cell, corresponding to a change in hydrogen ion concentration.
Synonyms: cell pH regulation; cellular hydrogen ion homeostasis; cellular pH regulation; pH regulation in cell; proton homeostasis; regulation of cell pH; regulation of cellular pH
negative regulation of corticotropin-releasing hormone secretion (GO:0051465)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.
Synonyms: down regulation of corticotropin-releasing hormone secretion; down-regulation of corticotropin-releasing hormone secretion; downregulation of corticotropin-releasing hormone secretion; inhibition of corticotropin-releasing hormone secretion; negative regulation of corticotropin-releasing factor secretion; negative regulation of CRF secretion; negative regulation of CRH secretion
glucosylglycerol transmembrane transport (GO:0051475)
Namespace: biological_process
Definition: The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, across a membrane.
Synonyms: glucosylglycerol transport
mannosylglycerate transmembrane transporter activity (GO:0051477)
Namespace: molecular_function
Definition: Enables the transfer of a mannosylglycerate from one side of a membrane to the other.
mannosylglycerate metabolic process (GO:0051478)
Namespace: biological_process
Definition: The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.
Synonyms: mannosylglycerate metabolism
obsolete ergosterol UDP-glucosyltransferase activity (GO:0051506)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol.
Comment: This term was obsoleted because it represents a specific substrate of sterol 3-beta-glucosyltransferase activity ; GO:0016906.
3 iron, 4 sulfur cluster binding (GO:0051538)
Namespace: molecular_function
Definition: Binding to a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
Synonyms: 3 Fe 4 S cluster binding; 3 iron, 4 sulphur cluster binding; 3Fe-4S cluster binding; iron-sulfur cluster 3Fe-4S binding; iron-sulphur cluster 3Fe-4S binding; triiron tetrasulfide cluster binding; triiron tetrasulphide cluster binding
elastin metabolic process (GO:0051541)
Namespace: biological_process
Definition: The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
Synonyms: elastin metabolism
flavonol biosynthetic process (GO:0051555)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
obsolete leucoanthocyanidin metabolic process (GO:0051556)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
Synonyms: leucoanthocyanidin metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
exocyst localization (GO:0051601)
Namespace: biological_process
Definition: Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
Synonyms: establishment and maintenance of exocyst localization; exocyst localisation
negative regulation of serotonin uptake (GO:0051612)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.
Synonyms: down regulation of serotonin uptake; down-regulation of serotonin uptake; downregulation of serotonin uptake; negative regulation of 5-HT uptake; negative regulation of 5-hydroxytryptamine uptake; negative regulation of 5HT uptake; negative regulation of serotonin import
spindle localization (GO:0051653)
Namespace: biological_process
Definition: Any process in which is the spindle is transported to, and/or maintained in, a specific location.
Synonyms: establishment and maintenance of spindle localization; spindle localisation