LiteFold/GO huggingface dataset:
obsolete intrinsic component of chloroplast outer membrane (GO:0031358)
Namespace: cellular_component
Definition: OBSOLETE. The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to chloroplast outer membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
nuclear RNA-directed RNA polymerase complex (GO:0031380)
Namespace: cellular_component
Definition: A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.
Synonyms: Rdr1 complex; RDRC
regulation of initiation of mating projection growth (GO:0031384)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.
Elg1 RFC-like complex (GO:0031391)
Namespace: cellular_component
Definition: A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
Synonyms: Elg1-RFC; Elg1-RLC; RFC (Elg1)
oxylipin biosynthetic process (GO:0031408)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
Synonyms: oxylipin anabolism; oxylipin biosynthesis; oxylipin formation; oxylipin synthesis
invertasome (GO:0031421)
Namespace: cellular_component
Definition: A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.
polycistronic mRNA processing (GO:0031426)
Namespace: biological_process
Definition: The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.
negative regulation of mRNA 3'-end processing (GO:0031441)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.
Synonyms: down regulation of mRNA 3'-end processing; down-regulation of mRNA 3'-end processing; downregulation of mRNA 3'-end processing; inhibition of mRNA 3'-end processing
Cul5-RING ubiquitin ligase complex (GO:0031466)
Namespace: cellular_component
Definition: A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
Synonyms: CDL5 complex; CRL5 complex; cullin-RING ligase 5; EC2S complex; SCF5 complex
myosin VI complex (GO:0031476)
Namespace: cellular_component
Definition: A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
positive regulation of mating type switching (GO:0031496)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of mating type switching.
Synonyms: activation of mating type switching; stimulation of mating type switching; up regulation of mating type switching; up-regulation of mating type switching; upregulation of mating type switching
obsolete menthol metabolic process (GO:0031524)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
Synonyms: menthol metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
menthol biosynthetic process (GO:0031525)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
Synonyms: menthol anabolism; menthol biosynthesis; menthol formation; menthol synthesis
plus-end directed microtubule sliding (GO:0031535)
Namespace: biological_process
Definition: The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.
negative regulation of anthocyanin metabolic process (GO:0031538)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
Synonyms: down regulation of anthocyanin metabolic process; down-regulation of anthocyanin metabolic process; downregulation of anthocyanin metabolic process; inhibition of anthocyanin metabolic process; negative regulation of anthocyanin metabolism
positive regulation of anthocyanin metabolic process (GO:0031539)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
Synonyms: activation of anthocyanin metabolic process; positive regulation of anthocyanin metabolism; stimulation of anthocyanin metabolic process; up regulation of anthocyanin metabolic process; up-regulation of anthocyanin metabolic process; upregulation of anthocyanin metabolic process
peptidyl-proline 3-dioxygenase activity (GO:0031544)
Namespace: molecular_function
Definition: Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.
regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031548)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
Synonyms: regulation of BDNF receptor signaling pathway; regulation of BDNF receptor signalling pathway; regulation of brain-derived neurotrophic factor receptor signalling pathway
transcriptional attenuation by ribosome (GO:0031556)
Namespace: biological_process
Definition: A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.
Synonyms: ribosome-mediated transcriptional attenuation
obsolete induction of programmed cell death in response to chemical stimulus (GO:0031557)
Namespace: biological_process
Definition: OBSOLETE. A process which directly activates any of the steps required for programmed cell death as a result of a chemical stimulus.
Synonyms: induction of programmed cell death in response to chemical stimulus; induction of programmed cell death in response to chemical substance
Comment: This term was made obsolete because it is now superseded by better defined and more specific terms under the node of GO:0012501 programmed cell death.
obsolete negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031586)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
Synonyms: down regulation of IP3 receptor activity; down-regulation of IP3 receptor activity; downregulation of IP3 receptor activity; inhibition of IP3 receptor activity; negative regulation of inositol 1,4,5-trisphosphate receptor activity; negative regulation of IP3 receptor activity
Comment: This term was obsoleted because it represents a molecular function.
obsolete wybutosine metabolic process (GO:0031590)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
Synonyms: wybutosine metabolism; yW metabolic process; yW metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
cytosolic proteasome complex (GO:0031597)
Namespace: cellular_component
Definition: A proteasome complex found in the cytosol of a cell.
nuclear proteasome core complex, beta-subunit complex (GO:0031607)
Namespace: cellular_component
Definition: The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.
opioid receptor binding (GO:0031628)
Namespace: molecular_function
Definition: Binding to an opioid receptor.
response to nutrient levels (GO:0031667)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
cellular response to nutrient (GO:0031670)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
G-protein beta/gamma-subunit complex (GO:0031680)
Namespace: cellular_component
Definition: The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.
Synonyms: G-beta/G-gamma complex; heterotrimeric G-protein GTPase, beta-subunit
Comment: See also the cellular component term 'heterotrimeric G-protein complex ; GO:0005834'.
adenosine receptor binding (GO:0031685)
Namespace: molecular_function
Definition: Binding to an adenosine receptor.
Synonyms: adenosine receptor ligand
alpha-1B adrenergic receptor binding (GO:0031692)
Namespace: molecular_function
Definition: Binding to an alpha-1B adrenergic receptor.
Synonyms: alpha-1B adrenergic receptor ligand
apelin receptor binding (GO:0031704)
Namespace: molecular_function
Definition: Binding to an apelin receptor.
Synonyms: apelin receptor ligand; APJ receptor binding
endothelin B receptor binding (GO:0031708)
Namespace: molecular_function
Definition: Binding to an endothelin B receptor.
Synonyms: endothelin B receptor ligand
B1 bradykinin receptor binding (GO:0031712)
Namespace: molecular_function
Definition: Binding to a B1 bradykinin receptor.
Synonyms: B1 bradykinin receptor ligand
type 2 cannabinoid receptor binding (GO:0031719)
Namespace: molecular_function
Definition: Binding to a type 2 cannabinoid receptor.
Synonyms: type 2 cannabinoid receptor ligand
CCR6 chemokine receptor binding (GO:0031731)
Namespace: molecular_function
Definition: Binding to a CCR6 chemokine receptor.
Synonyms: CCR6 chemokine receptor ligand; LARC receptor binding
type 2 cysteinyl leukotriene receptor binding (GO:0031747)
Namespace: molecular_function
Definition: Binding to a type 2 cysteinyl leukotriene receptor.
Synonyms: type 2 cysteinyl leukotriene receptor ligand
Edg-1 sphingosine 1-phosphate receptor binding (GO:0031754)
Namespace: molecular_function
Definition: Binding to an Edg-1 sphingosine 1-phosphate receptor.
Synonyms: Edg-1 sphingosine 1-phosphate receptor ligand
type 3 galanin receptor binding (GO:0031766)
Namespace: molecular_function
Definition: Binding to a type 3 galanin receptor.
Synonyms: type 3 galanin receptor ligand
type 2 orexin receptor binding (GO:0031772)
Namespace: molecular_function
Definition: Binding to a type 2 orexin receptor.
Synonyms: OX2 orexin receptor binding; type 2 hypocretin receptor binding; type 2 hypocretin receptor ligand
G protein-coupled acetylcholine receptor binding (GO:0031789)
Namespace: molecular_function
Definition: Binding to a G protein-coupled acetylcholine receptor.
Synonyms: G-protein coupled acetylcholine receptor binding; M1 muscarinic acetylcholine receptor binding; M1 muscarinic acetylcholine receptor ligand; M2 muscarinic acetylcholine receptor binding; M2 muscarinic acetylcholine receptor ligand; M3 muscarinic acetylcholine receptor binding; M3 muscarinic acetylcholine receptor ligand; M4 muscarinic acetylcholine receptor binding; M4 muscarinic acetylcholine receptor ligand; M5 muscarinic acetylcholine receptor binding; M5 muscarinic acetylcholine receptor ligand; muscarinic acetylcholine receptor binding; muscarinic acetylcholine receptor ligand
type 2 metabotropic GABA receptor binding (GO:0031797)
Namespace: molecular_function
Definition: Binding to a type 2 metabotropic GABA receptor.
Synonyms: type 2 metabotropic GABA receptor ligand
type 2 metabotropic glutamate receptor binding (GO:0031799)
Namespace: molecular_function
Definition: Binding to a type 2 metabotropic glutamate receptor.
Synonyms: type 2 metabotropic glutamate receptor ligand
type 7 metabotropic glutamate receptor binding (GO:0031804)
Namespace: molecular_function
Definition: Binding to a type 7 metabotropic glutamate receptor.
Synonyms: type 7 metabotropic glutamate receptor ligand
oxytocin receptor binding (GO:0031855)
Namespace: molecular_function
Definition: Binding to an oxytocin receptor.
Synonyms: oxytocin receptor ligand
prolactin-releasing peptide receptor binding (GO:0031861)
Namespace: molecular_function
Definition: Binding to a prolactin-releasing peptide receptor.
Synonyms: prolactin-releasing peptide receptor ligand
prostanoid receptor binding (GO:0031862)
Namespace: molecular_function
Definition: Binding to a prostanoid receptor.
Synonyms: prostanoid receptor ligand
prostacyclin receptor binding (GO:0031869)
Namespace: molecular_function
Definition: Binding to a prostacyclin receptor.
Synonyms: prostacyclin receptor ligand; prostanoid IP receptor binding
taste receptor binding (GO:0031883)
Namespace: molecular_function
Definition: Binding to a taste receptor.
Synonyms: taste receptor ligand
V1B vasopressin receptor binding (GO:0031895)
Namespace: molecular_function
Definition: Binding to a V1B vasopressin receptor.
Synonyms: V1B vasopressin receptor ligand
microbody membrane (GO:0031903)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a microbody.
microbody lumen (GO:0031907)
Namespace: cellular_component
Definition: The volume enclosed by the membranes of a microbody.
pyridoxal transmembrane transporter activity (GO:0031925)
Namespace: molecular_function
Definition: Enables the transfer of pyridoxal from one side of a membrane to the other. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
Synonyms: pyridoxal transporter activity
obsolete regulation of chromatin silencing at telomere (GO:0031938)
Namespace: biological_process
Definition: OBSOLETE. Any process that affects the rate, extent or location of chromatin silencing at telomeres.
Synonyms: regulation of heterochromatic silencing at telomere
Comment: This term was obsoleted because there is no evidence that chromatin silencing /heterochromatin assembly are directly regulated.
regulation of glucocorticoid biosynthetic process (GO:0031946)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
positive regulation of protein autophosphorylation (GO:0031954)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
Synonyms: activation of protein amino acid autophosphorylation; positive regulation of protein amino acid autophosphorylation; stimulation of protein amino acid autophosphorylation; up regulation of protein amino acid autophosphorylation; up-regulation of protein amino acid autophosphorylation; upregulation of protein amino acid autophosphorylation
organelle envelope lumen (GO:0031970)
Namespace: cellular_component
Definition: The region between the inner and outer lipid bilayers of an organelle envelope.
Synonyms: organelle intermembrane space
energy transducer activity (GO:0031992)
Namespace: molecular_function
Definition: The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.
Synonyms: light harvesting activity; photon capture
obsolete N-terminal myristoylation domain binding (GO:0031997)
Namespace: molecular_function
Definition: OBSOLETE. Binding to the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.
Comment: It is beyond GO scope.
NELF complex (GO:0032021)
Namespace: cellular_component
Definition: A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.
Synonyms: negative elongation factor complex
myosin I head/neck binding (GO:0032031)
Namespace: molecular_function
Definition: Binding to the head/neck region of a myosin I heavy chain.
myosin II tail binding (GO:0032035)
Namespace: molecular_function
Definition: Binding to the tail region of a myosin II heavy chain.
myosin heavy chain binding (GO:0032036)
Namespace: molecular_function
Definition: Binding to a heavy chain of a myosin complex.
mitochondrial DNA catabolic process (GO:0032043)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.
Synonyms: mitochondrial DNA breakdown; mitochondrial DNA catabolism; mitochondrial DNA degradation; mtDNA breakdown; mtDNA catabolic process; mtDNA catabolism; mtDNA degradation
cardiolipin biosynthetic process (GO:0032049)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
Synonyms: diphosphatidylglycerol biosynthesis; diphosphatidylglycerol biosynthetic process
bleb assembly (GO:0032060)
Namespace: biological_process
Definition: The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
Synonyms: blebbing; cell blebbing; membrane blebbing; plasma membrane bleb assembly; plasma membrane blebbing
type IV site-specific deoxyribonuclease activity (GO:0032067)
Namespace: molecular_function
Definition: Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).
Synonyms: type IV restriction enzyme activity
positive regulation of endodeoxyribonuclease activity (GO:0032079)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
Synonyms: activation of endodeoxyribonuclease activity; endodeoxyribonuclease activator; stimulation of endodeoxyribonuclease activity; up regulation of endodeoxyribonuclease activity; up-regulation of endodeoxyribonuclease activity; upregulation of endodeoxyribonuclease activity
positive regulation of protein binding (GO:0032092)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein binding.
Synonyms: activation of protein binding; stimulation of protein binding; up regulation of protein binding; up-regulation of protein binding; upregulation of protein binding
negative regulation of response to food (GO:0032096)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.
Synonyms: down regulation of response to food; down-regulation of response to food; downregulation of response to food; inhibition of response to food
positive regulation of appetite (GO:0032100)
Namespace: biological_process
Definition: Any process that increases appetite.
Synonyms: activation of appetite; appetite stimulation; positive regulation of hunger; stimulation of appetite; up regulation of appetite; up-regulation of appetite; upregulation of appetite
regulation of response to nutrient levels (GO:0032107)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a response to nutrient levels.
negative regulation of response to nutrient levels (GO:0032108)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.
Synonyms: down regulation of response to nutrient levels; down-regulation of response to nutrient levels; downregulation of response to nutrient levels; inhibition of response to nutrient levels
ascospore-type prospore membrane formation (GO:0032120)
Namespace: biological_process
Definition: The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
Synonyms: ascospore-type prospore membrane assembly; forespore membrane biosynthesis; forespore membrane formation; FSM assembly; FSM biosynthesis; FSM formation; prospore membrane biogenesis
dense core granule membrane (GO:0032127)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a dense core granule.
Synonyms: dense core vesicle membrane
medial membrane band assembly (GO:0032130)
Namespace: biological_process
Definition: The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.
Synonyms: medial membrane band formation
O6-alkylguanine-DNA binding (GO:0032132)
Namespace: molecular_function
Definition: Binding to an O6-alkylguanine adduct in DNA.
guanine/thymine mispair binding (GO:0032137)
Namespace: molecular_function
Definition: Binding to a double-stranded DNA region containing a G/T mispair.
Synonyms: G/T mispair binding; T/G mispair binding; thymine/guanine mispair binding