LiteFold/GO huggingface dataset:
activation of plasma proteins involved in acute inflammatory response (GO:0002541)
Namespace: biological_process
Definition: Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
Factor XII activation (GO:0002542)
Namespace: biological_process
Definition: Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.
Synonyms: Hageman factor activation
chronic inflammatory response to non-antigenic stimulus (GO:0002545)
Namespace: biological_process
Definition: A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.
basophil mediated immunity (GO:0002560)
Namespace: biological_process
Definition: Any process involved in the carrying out of an immune response by a basophil.
basophil degranulation (GO:0002561)
Namespace: biological_process
Definition: The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
somatic diversification of immune receptors via somatic mutation (GO:0002566)
Namespace: biological_process
Definition: The process in which immune receptor genes are diversified through somatic mutation.
somatic diversification of immune receptors by N region addition (GO:0002569)
Namespace: biological_process
Definition: The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.
regulation of antigen processing and presentation of peptide antigen (GO:0002583)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
Synonyms: regulation of peptide antigen processing and presentation
negative regulation of macrophage antigen processing and presentation (GO:0002617)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.
Synonyms: down regulation of macrophage antigen processing and presentation; down-regulation of macrophage antigen processing and presentation; downregulation of macrophage antigen processing and presentation; inhibition of macrophage antigen processing and presentation
regulation of non-professional antigen presenting cell antigen processing and presentation (GO:0002619)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
negative regulation of T cell antigen processing and presentation (GO:0002626)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.
Synonyms: down regulation of T cell antigen processing and presentation; down-regulation of T cell antigen processing and presentation; downregulation of T cell antigen processing and presentation; inhibition of T cell antigen processing and presentation; negative regulation of T lymphocyte antigen processing and presentation; negative regulation of T-cell antigen processing and presentation; negative regulation of T-lymphocyte antigen processing and presentation
positive regulation of germinal center formation (GO:0002636)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of germinal center formation.
Synonyms: activation of germinal center formation; stimulation of germinal center formation; up regulation of germinal center formation; up-regulation of germinal center formation; upregulation of germinal center formation
negative regulation of immunoglobulin production (GO:0002638)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
Synonyms: down regulation of immunoglobulin production; down-regulation of immunoglobulin production; downregulation of immunoglobulin production; inhibition of immunoglobulin production; negative regulation of immunoglobulin biosynthetic process; negative regulation of immunoglobulin secretion
negative regulation of tolerance induction to self antigen (GO:0002650)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.
Synonyms: down regulation of tolerance induction to self antigen; down-regulation of tolerance induction to self antigen; downregulation of tolerance induction to self antigen; inhibition of tolerance induction to self antigen
positive regulation of acute inflammatory response (GO:0002675)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
Synonyms: activation of acute inflammatory response; stimulation of acute inflammatory response; up regulation of acute inflammatory response; up-regulation of acute inflammatory response; upregulation of acute inflammatory response
respiratory burst involved in defense response (GO:0002679)
Namespace: biological_process
Definition: A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
regulation of immune system process (GO:0002682)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of an immune system process.
regulation of cytokine production involved in immune response (GO:0002718)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
Synonyms: regulation of cytokine biosynthetic process involved in immune response; regulation of cytokine production during immune response; regulation of cytokine secretion involved in immune response
negative regulation of cytokine production involved in immune response (GO:0002719)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
Synonyms: down regulation of cytokine production during immune response; down-regulation of cytokine production during immune response; downregulation of cytokine production during immune response; inhibition of cytokine production during immune response; negative regulation of cytokine biosynthetic process involved in immune response; negative regulation of cytokine production during immune response; negative regulation of cytokine secretion involved in immune response
positive regulation of cytokine production involved in immune response (GO:0002720)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.
Synonyms: activation of cytokine production during immune response; positive regulation of cytokine biosynthetic process involved in immune response; positive regulation of cytokine production during immune response; positive regulation of cytokine secretion involved in immune response; stimulation of cytokine production during immune response; up regulation of cytokine production during immune response; up-regulation of cytokine production during immune response; upregulation of cytokine production during immune response
negative regulation of T cell cytokine production (GO:0002725)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.
Synonyms: down regulation of T cell cytokine production; down-regulation of T cell cytokine production; downregulation of T cell cytokine production; inhibition of T cell cytokine production; negative regulation of T lymphocyte cytokine production; negative regulation of T-cell cytokine production; negative regulation of T-lymphocyte cytokine production
positive regulation of T cell cytokine production (GO:0002726)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.
Synonyms: activation of T cell cytokine production; positive regulation of T lymphocyte cytokine production; positive regulation of T-cell cytokine production; positive regulation of T-lymphocyte cytokine production; stimulation of T cell cytokine production; up regulation of T cell cytokine production; up-regulation of T cell cytokine production; upregulation of T cell cytokine production
antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen (GO:0002748)
Namespace: biological_process
Definition: Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).
Synonyms: antigen processing and presentation initiated by PAMP receptor mediated uptake of antigen; antigen processing and presentation initiated by PRR mediated uptake of antigen
innate immune response-inhibiting signal transduction (GO:0002766)
Namespace: biological_process
Definition: The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.
Fc receptor mediated inhibitory signaling pathway (GO:0002774)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
Synonyms: Fc receptor mediated inhibitory signalling pathway; Fc-receptor mediated inhibitory signaling pathway
positive regulation of antibacterial peptide production (GO:0002803)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.
Synonyms: activation of antibacterial peptide production; stimulation of antibacterial peptide production; up regulation of antibacterial peptide production; up-regulation of antibacterial peptide production; upregulation of antibacterial peptide production
positive regulation of antimicrobial peptide biosynthetic process (GO:0002807)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.
Synonyms: activation of antimicrobial peptide biosynthetic process; stimulation of antimicrobial peptide biosynthetic process; up regulation of antimicrobial peptide biosynthetic process; up-regulation of antimicrobial peptide biosynthetic process; upregulation of antimicrobial peptide biosynthetic process
negative regulation of adaptive immune response (GO:0002820)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
Synonyms: down regulation of adaptive immune response; down-regulation of adaptive immune response; downregulation of adaptive immune response; inhibition of adaptive immune response
negative regulation of T-helper 1 type immune response (GO:0002826)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.
Synonyms: down regulation of T-helper 1 type immune response; down-regulation of T-helper 1 type immune response; downregulation of T-helper 1 type immune response; inhibition of T-helper 1 type immune response
regulation of type 2 immune response (GO:0002828)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of a type 2 immune response.
Synonyms: regulation of T-helper 2 type immune response; regulation of Th2 immune response
negative regulation of T cell mediated immune response to tumor cell (GO:0002841)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
Synonyms: down regulation of T cell mediated immune response to tumor cell; down-regulation of T cell mediated immune response to tumor cell; downregulation of T cell mediated immune response to tumor cell; inhibition of T cell mediated immune response to tumor cell; negative regulation of T cell mediated immune response to tumour cell; negative regulation of T lymphocyte mediated immune response to tumor cell; negative regulation of T-cell mediated immune response to tumor cell; negative regulation of T-lymphocyte mediated immune response to tumor cell
regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002852)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
negative regulation of natural killer cell tolerance induction (GO:0002872)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.
Synonyms: down regulation of natural killer cell tolerance induction; down-regulation of natural killer cell tolerance induction; downregulation of natural killer cell tolerance induction; inhibition of natural killer cell tolerance induction; negative regulation of NK cell tolerance induction
positive regulation of natural killer cell tolerance induction (GO:0002873)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.
Synonyms: activation of natural killer cell tolerance induction; positive regulation of NK cell tolerance induction; stimulation of natural killer cell tolerance induction; up regulation of natural killer cell tolerance induction; up-regulation of natural killer cell tolerance induction; upregulation of natural killer cell tolerance induction
negative regulation of hypersensitivity (GO:0002884)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
Synonyms: down regulation of hypersensitivity; down-regulation of hypersensitivity; downregulation of hypersensitivity; inhibition of hypersensitivity
regulation of type II hypersensitivity (GO:0002892)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
regulation of central B cell deletion (GO:0002898)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of central B cell deletion.
regulation of peripheral B cell deletion (GO:0002908)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.
positive regulation of peripheral B cell anergy (GO:0002919)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.
Synonyms: activation of peripheral B cell anergy; stimulation of peripheral B cell anergy; up regulation of peripheral B cell anergy; up-regulation of peripheral B cell anergy; upregulation of peripheral B cell anergy
negative regulation of humoral immune response (GO:0002921)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
Synonyms: down regulation of humoral immune response; down-regulation of humoral immune response; downregulation of humoral immune response; inhibition of humoral immune response
positive regulation of humoral immune response (GO:0002922)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
Synonyms: activation of humoral immune response; stimulation of humoral immune response; up regulation of humoral immune response; up-regulation of humoral immune response; upregulation of humoral immune response
regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
synoviocyte proliferation (GO:0002941)
Namespace: biological_process
Definition: The multiplication or reproduction of type B synoviocytes by cell division, resulting in the expansion of their population. A type B synoviocyte is a fibroblast-like cell found in synovial tissues.
tRNA threonylcarbamoyladenosine modification (GO:0002949)
Namespace: biological_process
Definition: The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
Synonyms: t6A biosynthesis; t6A biosynthetic process; t6A tRNA modification; threonylcarbamoyladenosine anabolism; threonylcarbamoyladenosine biosynthesis; threonylcarbamoyladenosine biosynthetic process; threonylcarbamoyladenosine formation; threonylcarbamoyladenosine synthesis
developmental process involved in reproduction (GO:0003006)
Namespace: biological_process
Definition: A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring.
Synonyms: puberty; reproductive developmental process
lymph circulation (GO:0003017)
Namespace: biological_process
Definition: The flow of lymph through the body of an animal.
central nervous system control of baroreceptor feedback (GO:0003019)
Namespace: biological_process
Definition: The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.
detection of pH by chemoreceptor signaling (GO:0003022)
Namespace: biological_process
Definition: The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.
Synonyms: detection of pH by chemoreceptor signalling
obsolete vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure (GO:0003042)
Namespace: biological_process
Definition: OBSOLETE. A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
Synonyms: vasoconstriction of artery during carotid body chemoreceptor response to lowering of systemic arterial blood pressure
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
regulation of systemic arterial blood pressure by epinephrine (GO:0003047)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.
Synonyms: blood pressure regulation by epinephrine; regulation of blood pressure by adrenaline
regulation of systemic arterial blood pressure by acetylcholine (GO:0003068)
Namespace: biological_process
Definition: The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.
Synonyms: blood pressure regulation by acetylcholine
acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0003069)
Namespace: biological_process
Definition: The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.
Synonyms: vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure
regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)
Namespace: biological_process
Definition: The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.
Synonyms: blood pressure regulation by renin-angiotensin
pressure natriuresis (GO:0003095)
Namespace: biological_process
Definition: The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).
heart induction (GO:0003129)
Namespace: biological_process
Definition: The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
obsolete endodermal-mesodermal cell signaling involved in heart induction (GO:0003134)
Namespace: biological_process
Definition: OBSOLETE. Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.
Synonyms: endodermal-mesodermal cell signalling involved in heart induction
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
embryonic heart tube formation via epithelial folding (GO:0003145)
Namespace: biological_process
Definition: The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.
heart jogging (GO:0003146)
Namespace: biological_process
Definition: The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
Synonyms: cardiac jogging
neural crest cell migration involved in heart formation (GO:0003147)
Namespace: biological_process
Definition: The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.
cardiac chamber development (GO:0003205)
Namespace: biological_process
Definition: The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.
cardiac right atrium formation (GO:0003217)
Namespace: biological_process
Definition: The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.
right ventricular cardiac muscle tissue morphogenesis (GO:0003221)
Namespace: biological_process
Definition: The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.
Synonyms: right ventricle myocardium morphogenesis
left ventricular compact myocardium morphogenesis (GO:0003224)
Namespace: biological_process
Definition: The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.
conus arteriosus development (GO:0003238)
Namespace: biological_process
Definition: The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.