LiteFold/GO huggingface dataset:
cyclopropane-fatty-acyl-phospholipid synthase activity (GO:0008825)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Synonyms: CFA synthase activity; cyclopropane fatty acid synthase activity; cyclopropane fatty acid synthetase activity; cyclopropane synthase activity; cyclopropane synthetase activity; S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (cyclizing); unsaturated-phospholipid methyltransferase activity
diaminohydroxyphosphoribosylaminopyrimidine deaminase activity (GO:0008835)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O + H+ = 5-amino-6-(5-phosphoribosylamino)uracil + NH4.
Synonyms: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate deaminase activity; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine 2-aminohydrolase activity; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 2-aminohydrolase activity
4-hydroxy-tetrahydrodipicolinate synthase activity (GO:0008840)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O + H+.
Synonyms: DHDPS activity; dihydrodipicolinate synthase activity; dihydrodipicolinate synthetase activity; dihydrodipicolinic acid synthase activity; L-aspartate-4-semialdehyde hydro-lyase (adding pyruvate and cyclizing); L-aspartate-4-semialdehyde hydro-lyase [adding pyruvate and cyclizing; (S)-2,3-dihydropyridine-2,6-dicarboxylate-forming]
fructuronate reductase activity (GO:0008866)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-mannonate + NAD+ = D-fructuronate + H+ + NADH.
Synonyms: D-mannonate dehydrogenase activity; D-mannonate oxidoreductase activity; D-mannonate:NAD oxidoreductase activity; D-mannonate:NAD+ 5-oxidoreductase activity; mannonate oxidoreductase activity; mannonic dehydrogenase activity
galactitol-1-phosphate 5-dehydrogenase activity (GO:0008868)
Namespace: molecular_function
Definition: Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.
Synonyms: galactitol-1-phosphate:NAD+ oxidoreductase activity
glucose-1-phosphatase activity (GO:0008877)
Namespace: molecular_function
Definition: Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.
Synonyms: alpha-D-glucose-1-phosphate phosphohydrolase activity; D-glucose-1-phosphate phosphohydrolase activity
glucuronate isomerase activity (GO:0008880)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-glucuronate = D-fructuronate. Also converts D-galacturonate to D-tagaturonate.
Synonyms: D-glucuronate aldose-ketose-isomerase activity; D-glucuronate isomerase activity; D-glucuronate ketol-isomerase activity; uronate isomerase activity; uronic acid isomerase activity; uronic isomerase activity
glycerate kinase activity (GO:0008887)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H+.
Synonyms: ATP:(R)-glycerate 3-phosphotransferase activity; ATP:D-glycerate 2-phosphotransferase activity; D-glycerate 3-kinase activity; D-glycerate kinase activity; D-glyceric acid kinase activity; GK; glycerate kinase (phosphorylating); glycerate-3-kinase activity
S-adenosylmethionine-homocysteine S-methyltransferase activity (GO:0008898)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.
Synonyms: adenosylmethionine transmethylase activity; adenosylmethionine:homocysteine methyltransferase activity; homocysteine methyltransferase activity; homocysteine transmethylase activity; L-homocysteine S-methyltransferase activity; S-adenosyl-L-methionine:L-homocysteine methyltransferase activity; S-adenosyl-L-methionine:L-homocysteine S-methyltransferase activity; S-adenosylmethionine homocysteine transmethylase activity; S-adenosylmethionine-homocysteine transmethylase activity; S-adenosylmethionine:homocysteine methyltransferase activity
lipopolysaccharide-1,6-galactosyltransferase activity (GO:0008921)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.
Synonyms: LPS-1,6-galactosyltransferase activity
long-chain fatty acid [acyl-carrier-protein] ligase activity (GO:0008922)
Namespace: molecular_function
Definition: Catalysis of the reaction: a long-chain fatty acid + ATP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Synonyms: acyl-[acyl-carrier-protein] synthetase activity; acyl-ACP synthetase activity; acyl-acyl carrier protein synthetase; acyl-acyl-carrier-protein synthetase activity; acyl-acyl-carrier-proteinsynthetase activity; long-chain fatty acid-[acyl-carrier-protein] ligase activity; long-chain-fatty-acid-[acyl-carrier protein] ligase activity; long-chain-fatty-acid-[acyl-carrier-protein] ligase activity; long-chain-fatty-acid-ACP ligase activity; long-chain-fatty-acid-acyl-carrier-protein ligase activity; long-chain-fatty-acid:acyl-carrier-protein ligase (AMP-forming) activity; stearoyl-ACP synthetase activity
Comment: While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
nitric oxide dioxygenase NAD(P)H activity (GO:0008941)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 NO + 2 O2 + NAD(P)H + H+ = 2 nitrate + NAD(P)+.
Synonyms: nitric oxide dioxygenase activity; NOD activity
Comment: Note that this activity is similar to nitric oxide dioxygenase activity, heme protein ; GO:0141118, but GO:0141118 uses a heme protein as the electron donor.
obsolete oligopeptidase A activity (GO:0008944)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-Gly-Pro-Ala is cleaved at the Gly-Gly bond, but not Z-(Gly)5.
Synonyms: 68000-M signalpeptide hydrolase activity; oligopeptidase A activity
Comment: This term was made obsolete because it represents a gene product.
phosphatidylglycerophosphatase activity (GO:0008962)
Namespace: molecular_function
Definition: Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
Synonyms: PGP phosphatase activity; phosphatidylglycerol phosphatase activity; phosphatidylglycerol phosphate phosphatase activity; phosphatidylglycerophosphate phosphohydrolase activity
rRNA (adenine-N6-)-methyltransferase activity (GO:0008988)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosine in rRNA + S-adenosyl-L-methionine = H+ + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine.
Synonyms: ErmC 23S rRNA methyltransferase; gene ksgA methyltransferase; ribonucleic acid-adenine (N(6)) methylase activity; ribonucleic acid-adenine (N6) methylase activity; ribosomal ribonucleate adenine 6-methyltransferase activity; S-adenosyl-L-methionine:rRNA (adenine-6-N-)-methyltransferase activity; S-adenosyl-L-methionine:rRNA (adenine-N6-)-methyltransferase activity
sorbitol-6-phosphate 2-dehydrogenase activity (GO:0009010)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
Synonyms: D-glucitol-6-phosphate dehydrogenase activity; D-sorbitol 6-phosphate dehydrogenase activity; D-sorbitol-6-phosphate dehydrogenase activity; D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase activity; glucitol-6-phosphate dehydrogenase activity; ketosephosphate reductase activity; sorbitol-6-P-dehydrogenase activity
alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity (GO:0009011)
Namespace: molecular_function
Definition: Catalysis of the reaction: [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + ADP + H+.
Synonyms: adenosine diphosphate glucose-starch glucosyltransferase activity; adenosine diphosphoglucose-starch glucosyltransferase activity; ADP-glucose starch synthase activity; ADP-glucose transglucosylase activity; ADP-glucose--starch glucosyltransferase activity; ADP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity; ADPG starch synthetase activity; ADPG-starch glucosyltransferase activity; ADPglucose-starch glucosyltransferase activity; ADPglucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase activity; glycogen synthase activity; starch (bacterial glycogen) synthase activity; starch synthase activity; starch synthetase activity
succinate-semialdehyde dehydrogenase [NAD(P)+] activity (GO:0009013)
Namespace: molecular_function
Definition: Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
Synonyms: succinate semialdehyde dehydrogenase (nicotinamide adenine dinucleotide (phosphate)); succinate-semialdehyde:NAD(P)+ oxidoreductase activity
tagaturonate reductase activity (GO:0009026)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.
Synonyms: altronate dehydrogenase activity; altronate oxidoreductase activity; altronic oxidoreductase activity; D-altronate:NAD+ 3-oxidoreductase activity; D-tagaturonate reductase activity; tagaturonate dehydrogenase activity; TagUAR
tartronate-semialdehyde synthase activity (GO:0009028)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 glyoxylate + H+ = 2-hydroxy-3-oxopropanoate + CO2.
Synonyms: glyoxalate carboligase activity; glyoxylate carbo-ligase activity; glyoxylate carboligase activity; glyoxylate carboxy-lyase (dimerizing); glyoxylate carboxy-lyase (dimerizing; tartronate-semialdehyde-forming); glyoxylic carbo-ligase activity; hydroxymalonic semialdehyde carboxylase activity; tartronate semialdehyde carboxylase activity; tartronic semialdehyde carboxylase activity
tryptophanase activity (GO:0009034)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-tryptophan + H2O = indole + NH4 + pyruvate.
Synonyms: L-tryptophan indole-lyase (deaminating) activity; L-tryptophan indole-lyase (deaminating; pyruvate forming) activity; L-tryptophan indole-lyase activity; L-tryptophanase activity; TNase activity; tryptophan catabolic process, using tryptophanase; tryptophan catabolism, using tryptophanase
dosage compensation by hyperactivation of X chromosome (GO:0009047)
Namespace: biological_process
Definition: Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
pentose-phosphate shunt, non-oxidative branch (GO:0009052)
Namespace: biological_process
Definition: The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.
Synonyms: pentose phosphate pathway, non-oxidative branch; pentose phosphate shunt, non-oxidative branch; pentose-phosphate pathway, non-oxidative branch
macromolecule biosynthetic process (GO:0009059)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
Synonyms: biopolymer biosynthetic process; macromolecule anabolism; macromolecule biosynthesis; macromolecule formation; macromolecule synthesis
Comment: Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
obsolete aspartate family amino acid catabolic process (GO:0009068)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
Synonyms: aspartate family amino acid breakdown; aspartate family amino acid catabolism; aspartate family amino acid degradation
Comment: The reason for obsoletion is that this is an unnecessary grouping term.
L-lysine biosynthetic process (GO:0009085)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-lysine, 2,6-diaminohexanoic acid.
Synonyms: lysine anabolism; lysine biosynthesis; lysine formation; lysine synthesis
L-threonine biosynthetic process (GO:0009088)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
Synonyms: threonine anabolism; threonine biosynthesis; threonine formation; threonine synthesis
L-homoserine metabolic process (GO:0009092)
Namespace: biological_process
Definition: The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
Synonyms: homoserine metabolism
vitamin catabolic process (GO:0009111)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body, carried out by individual cells.
Synonyms: vitamin breakdown; vitamin catabolism; vitamin degradation
nucleoside diphosphate catabolic process (GO:0009134)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
Synonyms: nucleoside diphosphate breakdown; nucleoside diphosphate catabolism; nucleoside diphosphate degradation
purine ribonucleotide biosynthetic process (GO:0009152)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms: purine ribonucleotide anabolism; purine ribonucleotide biosynthesis; purine ribonucleotide formation; purine ribonucleotide synthesis
pyrimidine deoxyribonucleoside diphosphate biosynthetic process (GO:0009197)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
Synonyms: pyrimidine deoxyribonucleoside diphosphate anabolism; pyrimidine deoxyribonucleoside diphosphate biosynthesis; pyrimidine deoxyribonucleoside diphosphate formation; pyrimidine deoxyribonucleoside diphosphate synthesis
purine ribonucleoside triphosphate catabolic process (GO:0009207)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
Synonyms: purine ribonucleoside triphosphate breakdown; purine ribonucleoside triphosphate catabolism; purine ribonucleoside triphosphate degradation
purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)
Namespace: biological_process
Definition: The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
Synonyms: purine deoxyribonucleoside triphosphate metabolism
pyrimidine ribonucleotide metabolic process (GO:0009218)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
Synonyms: pyrimidine ribonucleotide metabolism
siderophore metabolic process (GO:0009237)
Namespace: biological_process
Definition: The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
Synonyms: siderochrome metabolic process; siderochrome metabolism; siderophore metabolism
isopentenyl diphosphate biosynthetic process (GO:0009240)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
Synonyms: IPP biosynthesis; IPP biosynthetic process; isopentenyl diphosphate anabolism; isopentenyl diphosphate biosynthesis; isopentenyl diphosphate formation; isopentenyl diphosphate synthesis; isopentenyl pyrophosphate biosynthesis; isopentenyl pyrophosphate biosynthetic process
enterobacterial common antigen biosynthetic process (GO:0009246)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
Synonyms: enterobacterial common antigen anabolism; enterobacterial common antigen biosynthesis; enterobacterial common antigen formation; enterobacterial common antigen synthesis
peptidoglycan catabolic process (GO:0009253)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls and consisting of long glycan strands of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid, cross-linked by short peptides.
Synonyms: murein catabolic process; murein catabolism; peptidoglycan breakdown; peptidoglycan catabolism; peptidoglycan degradation
response to humidity (GO:0009270)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.
cell outer membrane (GO:0009279)
Namespace: cellular_component
Definition: A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
Synonyms: outer membrane of cell
Comment: To annotate the plasma (cytoplasmic) membrane, see instead GO:0005886.
DNA import into cell involved in transformation (GO:0009290)
Namespace: biological_process
Definition: The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.
Synonyms: cellular DNA import during transformation; cellular DNA uptake; DNA import into cell; DNA transport into cell during transformation
tRNA transcription (GO:0009304)
Namespace: biological_process
Definition: The synthesis of transfer RNA (tRNA) from a DNA template.
Synonyms: tRNA biosynthesis; tRNA biosynthetic process; tRNA synthesis
protein secretion (GO:0009306)
Namespace: biological_process
Definition: The controlled release of proteins from a cell.
Synonyms: glycoprotein secretion; protein secretion during cell fate commitment; protein secretion resulting in cell fate commitment
3-isopropylmalate dehydratase complex (GO:0009316)
Namespace: cellular_component
Definition: A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
Synonyms: isopropylmalate isomerase complex
Comment: See also the molecular function term '3-isopropylmalate dehydratase activity ; GO:0003861'.
exodeoxyribonuclease VII complex (GO:0009318)
Namespace: cellular_component
Definition: An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.
polyphosphate kinase complex (GO:0009358)
Namespace: cellular_component
Definition: A protein complex that possesses polyphosphate kinase activity.
Comment: See also the molecular function term 'polyphosphate kinase activity ; GO:0008976'.
obsolete positive regulation of transcription by pheromones (GO:0009371)
Namespace: biological_process
Definition: OBSOLETE. Any process involving pheromones that activates or increases the rate of transcription.
Synonyms: activation of transcription by pheromones; stimulation of transcription by pheromones; up regulation of transcription by pheromones; up-regulation of transcription by pheromones; upregulation of transcription by pheromones
Comment: This term has been obsoleted because it represents a GO-CAM model.
HslUV protease complex (GO:0009376)
Namespace: cellular_component
Definition: A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.
Synonyms: ClpYQ protease complex
obsolete HslUV protease activity (GO:0009377)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the ATP-dependent hydrolysis of peptide bonds in substrates including E. coli SulA and misfolded proteins.
Synonyms: HslUV protease activity
Comment: This term was made obsolete because it represents a gene product.
phospholipid catabolic process (GO:0009395)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
Synonyms: phospholipid breakdown; phospholipid catabolism; phospholipid degradation
response to xenobiotic stimulus (GO:0009410)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms: drug resistance; drug susceptibility/resistance; response to drug