LiteFold/GO huggingface dataset:
calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity (GO:0048101)
Namespace: molecular_function
Definition: Catalysis of the reactions: nucleoside 3',5'-cyclic GMP + H2O = GMP + H+; this activity is activated by binding to calcium-bound calmodulin.
Synonyms: calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; calcium- and calmodulin-regulated cGMP phosphodiesterase activity; calcium- and calmodulin-regulated cGMP-specific phosphodiesterase activity; calcium- and calmodulin-regulated cyclic-GMP phosphodiesterase activity; calcium/calmodulin-regulated cGMP-specific phosphodiesterase activity
establishment of body hair planar orientation (GO:0048105)
Namespace: biological_process
Definition: Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.
obsolete peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine (GO:0048109)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.
Comment: This term was obsoleted because it represents a non-entymatic protein modification, see PMID:12802338.
female germ-line cyst encapsulation (GO:0048139)
Namespace: biological_process
Definition: Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.
regulation of fibroblast proliferation (GO:0048145)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
obsolete hyperphosphorylation (GO:0048151)
Namespace: biological_process
Definition: OBSOLETE. The excessive phosphorylation of a protein, as a result of activation of kinases, deactivation of phosphatases, or both.
Synonyms: hyperphosphorylation
Comment: This term was made obsolete because it is an unnecessary grouping term and was poorly defined.
mature follicle stage (GO:0048166)
Namespace: biological_process
Definition: The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.
Synonyms: mammalian oogenesis stage 9
elastic fiber assembly (GO:0048251)
Namespace: biological_process
Definition: Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
Synonyms: elastic fibre assembly; elastin fiber assembly; elastin fibre assembly
lauric acid metabolic process (GO:0048252)
Namespace: biological_process
Definition: The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
Synonyms: lauric acid metabolism; n-dodecanoic acid metabolic process; n-dodecanoic acid metabolism
methionine adenosyltransferase complex (GO:0048269)
Namespace: cellular_component
Definition: A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
Synonyms: MAT complex
determinate inflorescence morphogenesis (GO:0048282)
Namespace: biological_process
Definition: The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.
lung alveolus development (GO:0048286)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
Synonyms: alveolarization; alveologenesis
positive regulation of isotype switching to IgE isotypes (GO:0048295)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms: activation of isotype switching to IgE isotypes; positive regulation of class switch recombination to IgE isotypes; positive regulation of class switching to IgE isotypes; positive regulation of isotype switch recombination to IgE isotypes; stimulation of isotype switching to IgE isotypes; up regulation of isotype switching to IgE isotypes; up-regulation of isotype switching to IgE isotypes; upregulation of isotype switching to IgE isotypes
seed development (GO:0048316)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
axial mesodermal cell fate determination (GO:0048323)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Synonyms: axial mesoderm cell fate determination
mesoderm morphogenesis (GO:0048332)
Namespace: biological_process
Definition: The process in which the anatomical structures of the mesoderm are generated and organized.
regulation of mesodermal cell fate determination (GO:0048334)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.
negative regulation of paraxial mesodermal cell fate determination (GO:0048347)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.
Synonyms: down regulation of paraxial mesodermal cell fate determination; down-regulation of paraxial mesodermal cell fate determination; downregulation of paraxial mesodermal cell fate determination; inhibition of paraxial mesodermal cell fate determination
root development (GO:0048364)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
lateral mesodermal cell fate commitment (GO:0048372)
Namespace: biological_process
Definition: The process in which a cell becomes committed to become a lateral mesoderm cell.
Synonyms: lateral mesoderm cell fate commitment; lateral plate mesoderm cell fate commitment; lateral plate mesodermal cell fate commitment
lateral mesodermal cell fate determination (GO:0048373)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
Synonyms: lateral mesoderm cell fate determination; lateral plate mesoderm cell fate determination; lateral plate mesodermal cell fate determination
regulation of retinoic acid receptor signaling pathway (GO:0048385)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
Synonyms: regulation of RAR signaling pathway; regulation of retinoic acid receptor signalling pathway
regulation of intermediate mesodermal cell fate specification (GO:0048399)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.
petal formation (GO:0048451)
Namespace: biological_process
Definition: The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.
threonine-phosphate decarboxylase activity (GO:0048472)
Namespace: molecular_function
Definition: Catalysis of the reaction: O-phospho-L-threonine + H+ = (R)-1-aminopropan-2-yl phosphate + CO2.
Synonyms: CobD; L-threonine O-3-phosphate carboxy-lyase [(R)-1-aminopropan-2-yl-phosphate-forming]; L-threonine O-3-phosphate carboxy-lyase activity; L-threonine-O-3-phosphate decarboxylase activity
parasympathetic nervous system development (GO:0048486)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
anterograde synaptic vesicle transport (GO:0048490)
Namespace: biological_process
Definition: The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
Synonyms: anterograde axonal transport of synaptic vesicle
maintenance of floral organ identity (GO:0048497)
Namespace: biological_process
Definition: The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
embryonic meristem development (GO:0048508)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.
imaginal disc-derived wing expansion (GO:0048526)
Namespace: biological_process
Definition: The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
Synonyms: wing expansion; wing inflation
beta-1,3-galactosyltransferase activity (GO:0048531)
Namespace: molecular_function
Definition: Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.
anatomical structure arrangement (GO:0048532)
Namespace: biological_process
Definition: The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
Synonyms: anatomical structure organization; anatomical structure structural organization; organization of an anatomical structure; structural organization
lymph gland development (GO:0048542)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
Synonyms: haematopoietic organ development; haemopoietic organ development; hematopoietic organ development; hemopoietic organ development
recognition of pollen (GO:0048544)
Namespace: biological_process
Definition: A cell recognition process in which pollen is recognized and either accepted or rejected by cells in the stigma.
Synonyms: pollen recognition; recognition or rejection of self pollen; self incompatibility
regulation of pinocytosis (GO:0048548)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
embryonic organ development (GO:0048568)
Namespace: biological_process
Definition: Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
Synonyms: embryonic organogenesis
oocyte development (GO:0048599)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
embryonic ectodermal digestive tract development (GO:0048611)
Namespace: biological_process
Definition: The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.
Synonyms: embryonic ectodermal gut development
embryonic ectodermal digestive tract morphogenesis (GO:0048613)
Namespace: biological_process
Definition: The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
Synonyms: embryonic ectodermal gut morphogenesis
post-embryonic ectodermal digestive tract morphogenesis (GO:0048614)
Namespace: biological_process
Definition: The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.
Synonyms: post-embryonic ectodermal gut morphogenesis
regulation of muscle organ development (GO:0048634)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of muscle development.
muscle organ morphogenesis (GO:0048644)
Namespace: biological_process
Definition: The process in which the anatomical structures of muscle are generated and organized.
anther wall tapetum cell differentiation (GO:0048657)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
Synonyms: tapetal cell differentiation
neuron fate commitment (GO:0048663)
Namespace: biological_process
Definition: The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
Synonyms: neuron lineage restriction; neuronal lineage restriction
neuron fate determination (GO:0048664)
Namespace: biological_process
Definition: The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
neuron development (GO:0048666)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
cell morphogenesis involved in neuron differentiation (GO:0048667)
Namespace: biological_process
Definition: The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
Synonyms: neuron morphogenesis involved in differentiation
positive regulation of collateral sprouting (GO:0048672)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of collateral sprouting.
Synonyms: activation of collateral sprouting; stimulation of collateral sprouting; up regulation of collateral sprouting; up-regulation of collateral sprouting; upregulation of collateral sprouting
sprouting of injured axon (GO:0048682)
Namespace: biological_process
Definition: The process involved in sprouting of an injured axon.
embryonic cranial skeleton morphogenesis (GO:0048701)
Namespace: biological_process
Definition: The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
Synonyms: embryonic cranium morphogenesis
regulation of astrocyte differentiation (GO:0048710)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of astrocyte differentiation.
clypeus development (GO:0048723)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.
proboscis development (GO:0048728)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.
gland development (GO:0048732)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.
haltere morphogenesis (GO:0048735)
Namespace: biological_process
Definition: The process in which the anatomical structures of a haltere are generated and organized.
skeletal muscle fiber development (GO:0048741)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
Synonyms: skeletal muscle fibre development; skeletal myofiber development; skeletal myofibre development
plant parenchymal cell differentiation (GO:0048760)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.
Synonyms: parenchymal cell differentiation
collenchyma cell differentiation (GO:0048761)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.
regulation of erythrophore differentiation (GO:0048778)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of erythrophore differentiation.
swim bladder inflation (GO:0048798)
Namespace: biological_process
Definition: The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
Synonyms: gas bladder inflation
pigment cell precursor differentiation (GO:0048824)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.
Synonyms: chromatophore precursor differentiation
cotyledon morphogenesis (GO:0048826)
Namespace: biological_process
Definition: The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
artery morphogenesis (GO:0048844)
Namespace: biological_process
Definition: The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.
Synonyms: arterial morphogenesis; arteriogenesis
axon extension involved in axon guidance (GO:0048846)
Namespace: biological_process
Definition: The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
diencephalon morphogenesis (GO:0048852)
Namespace: biological_process
Definition: The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
anatomical structure development (GO:0048856)
Namespace: biological_process
Definition: The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
Synonyms: development of an anatomical structure
pollen tube development (GO:0048868)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.
homeostasis of number of retina cells (GO:0048877)
Namespace: biological_process
Definition: Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.
anterior lateral line neuromast cupula development (GO:0048904)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
peripheral nervous system neuron axonogenesis (GO:0048936)
Namespace: biological_process
Definition: Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
anterior lateral line nerve glial cell development (GO:0048939)
Namespace: biological_process
Definition: The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.