LiteFold/GO huggingface dataset:
prolactin secretion (GO:0070459)
Namespace: biological_process
Definition: The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
alpha1-beta1 integrin-alpha3(VI) complex (GO:0070465)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
Synonyms: ITGA1-ITGB1-COL6A3 complex
leukocyte aggregation (GO:0070486)
Namespace: biological_process
Definition: The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.
Synonyms: immune cell aggregation; leucocyte aggregation; white blood cell aggregation; white corpuscle aggregation
regulation of thrombin-activated receptor signaling pathway (GO:0070494)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
Synonyms: regulation of thrombin receptor signaling pathway; regulation of thrombin receptor signalling pathway
obsolete selenium-containing prosthetic group biosynthetic process (GO:0070504)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.
Synonyms: selenium-containing prosthetic group anabolism; selenium-containing prosthetic group biosynthesis; selenium-containing prosthetic group formation; selenium-containing prosthetic group synthesis
Comment: This term was obsoleted because it is an unnecessary grouping class.
cholesterol import (GO:0070508)
Namespace: biological_process
Definition: The directed movement of cholesterol into a cell or organelle.
Synonyms: cholesterol uptake
obsolete negative regulation of histone H4-K20 methylation (GO:0070511)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
Synonyms: down regulation of histone H4-K20 methylation; down-regulation of histone H4-K20 methylation; downregulation of histone H4-K20 methylation; inhibition of histone H4-K20 methylation
Comment: This term was obsoleted because it represents ergulation of a molecular function.
obsolete positive regulation of histone H4-K20 methylation (GO:0070512)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
Synonyms: activation of histone H4-K20 methylation; stimulation of histone H4-K20 methylation; up regulation of histone H4-K20 methylation; up-regulation of histone H4-K20 methylation; upregulation of histone H4-K20 methylation
Comment: This term was obsoleted because it represents a molecular function.
protein K63-linked ubiquitination (GO:0070534)
Namespace: biological_process
Definition: A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
Synonyms: protein K63-linked polyubiquitination
lysosomal multienzyme complex (GO:0070559)
Namespace: cellular_component
Definition: A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.
Synonyms: GALNS-lysosomal hydrolase 1.27 MDa complex
guanylyltransferase activity (GO:0070568)
Namespace: molecular_function
Definition: Catalysis of the transfer of a guanylyl group to an acceptor.
obsolete peptide mating pheromone maturation involved in regulation of pheromone-induced unidirectional conjugation (GO:0070575)
Namespace: biological_process
Definition: OBSOLETE. The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.
Synonyms: peptide mating pheromone formation involved in pheromone-induced unidirectional conjugation; peptide mating pheromone processing involved in pheromone-induced unidirectional conjugation
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
ascospore wall biogenesis (GO:0070591)
Namespace: biological_process
Definition: A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.
juvenile hormone response element binding (GO:0070594)
Namespace: molecular_function
Definition: Binding to a juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.
Synonyms: JHRE binding
cell wall (1->3)-alpha-glucan biosynthetic process (GO:0070598)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.
Synonyms: cell wall 1,3-alpha-glucan anabolism; cell wall 1,3-alpha-glucan biosynthesis; cell wall 1,3-alpha-glucan biosynthetic process; cell wall 1,3-alpha-glucan formation; cell wall 1,3-alpha-glucan synthesis; cell wall alpha-1,3-glucan anabolism; cell wall alpha-1,3-glucan biosynthesis; cell wall alpha-1,3-glucan biosynthetic process; cell wall alpha-1,3-glucan formation; cell wall alpha-1,3-glucan synthesis
obsolete regulation of (1->3)-alpha-glucan metabolic process (GO:0070605)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
Synonyms: regulation of 1,3-alpha-glucan metabolic process; regulation of 1,3-alpha-glucan metabolism; regulation of alpha-1,3 glucan metabolic process; regulation of alpha-1,3 glucan metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete regulation of cell wall (1->3)-alpha-glucan metabolic process (GO:0070607)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
Synonyms: regulation of cell wall 1,3-alpha-glucan metabolic process; regulation of cell wall 1,3-alpha-glucan metabolism; regulation of cell wall alpha-1,3 glucan metabolic process; regulation of cell wall alpha-1,3 glucan metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
histone H3R2 methyltransferase activity (GO:0070611)
Namespace: molecular_function
Definition: Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to the arginine residue at position 2 of histone H3.
Synonyms: histone H3R2 arginine methyltransferase activity; histone methylase activity (H3-R2 specific); histone methyltransferase activity (H3-R2 specific); histone-arginine N-methyltransferase activity (H3-R2 specific); histone-H3R2 methyltransferase activity
Comment: Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary across different genes within an organism.
transepithelial ammonium transport (GO:0070634)
Namespace: biological_process
Definition: The directed movement of ammonium ions from one side of an epithelium to the other.
asparaginyl-tRNAAsn biosynthesis via transamidation (GO:0070680)
Namespace: biological_process
Definition: A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.
seminal clot liquefaction (GO:0070684)
Namespace: biological_process
Definition: The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.
Synonyms: semen liquefaction
BMP receptor binding (GO:0070700)
Namespace: molecular_function
Definition: Binding to a BMP receptor.
Synonyms: bone morphogenetic protein receptor binding
RNA nucleotide deletion (GO:0070706)
Namespace: biological_process
Definition: The modification of an RNA molecule by removal of a single nucleotide.
Synonyms: RNA nucleotide excision
RNA uridine deletion (GO:0070710)
Namespace: biological_process
Definition: The modification of an RNA molecule by removal of a uridine nucleotide.
Synonyms: RNA U deletion; RNA uridine excision
RNA cytidine-uridine insertion (GO:0070712)
Namespace: biological_process
Definition: The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.
Synonyms: RNA CU insertion
cell wall assembly (GO:0070726)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
obsolete cellular macromolecule localization (GO:0070727)
Namespace: biological_process
Definition: OBSOLETE. Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
Synonyms: cellular macromolecule localisation
Comment: This term was obsoleted because it represents the same process as macromolecule localization ; GO:0033036.
cAMP transport (GO:0070730)
Namespace: biological_process
Definition: The directed movement of cyclic AMP (cAMP), into, out of or within a cell.
Synonyms: cyclic AMP transport
interleukin-27 complex (GO:0070744)
Namespace: cellular_component
Definition: A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
Synonyms: EBI3; IL-27 complex; IL27; p28
Comment: Note that this heterodimeric cytokine utilizes the same EBI3 subunit (product of EBI3, Epstein-Barr virus induced gene 3) as its beta chain as IL-35 uses for its beta chain. Also note that the product of the IL27 gene is the alpha subunit of IL-27. The functional IL-27 protein complex requires both subunits.
BRCA1-Rad51 complex (GO:0070767)
Namespace: cellular_component
Definition: A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.
dihydrosphingosine-1-phosphate phosphatase activity (GO:0070780)
Namespace: molecular_function
Definition: Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.
Synonyms: dihydrosphingosine-1-phosphate phosphohydrolase activity; sphinganine-1-phosphate phosphatase activity
cleistothecium development (GO:0070791)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
regulation of cleistothecium development (GO:0070796)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
tertiary granule membrane (GO:0070821)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a tertiary granule.
obsolete chromatin maintenance (GO:0070827)
Namespace: biological_process
Definition: OBSOLETE. The chromatin organization process that preserves chromatin in a stable functional or structural state.
Comment: This term was obsoleted because it is redundant with chromatin organization and assembly terms.
aggresome assembly (GO:0070842)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.
sterol-dependent protein binding (GO:0070866)
Namespace: molecular_function
Definition: Binding to a protein or protein complex in the presence of sterols.
negative regulation of glycogen metabolic process (GO:0070874)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
Synonyms: negative regulation of glycogen metabolism
fungal-type cell wall beta-glucan metabolic process (GO:0070879)
Namespace: biological_process
Definition: The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
Synonyms: fungal-type cell wall beta-glucan metabolism
fungal-type cell wall beta-glucan biosynthetic process (GO:0070880)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
Synonyms: fungal-type cell wall beta-glucan anabolism; fungal-type cell wall beta-glucan biosynthesis; fungal-type cell wall beta-glucan formation; fungal-type cell wall beta-glucan synthesis
mitochondrial tRNA pseudouridine synthesis (GO:0070902)
Namespace: biological_process
Definition: The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.
L-histidine:histamine antiporter activity (GO:0070907)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-histidine(out) + histamine(in) = L-histidine(in) + histamine(out).
Synonyms: histidine-histamine antiporter activity; histidine/histamine antiporter activity; histidine:histamine antiporter activity
UV-damage excision repair (GO:0070914)
Namespace: biological_process
Definition: A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
Synonyms: AER; alternative excision repair; UV-damaged DNA endonuclease-dependent excision repair; UVDE-dependent excision repair; UVER
Dsl1/NZR complex (GO:0070939)
Namespace: cellular_component
Definition: A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.
Synonyms: CATCHR family complex; Dsl1p complex; NZR complex
Comment: See also the molecular function term 'acetolactate synthase activity ; GO:0003984'.
obsolete dephosphorylation of RNA polymerase II C-terminal domain (GO:0070940)
Namespace: biological_process
Definition: OBSOLETE. The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
Synonyms: CTD domain dephosphorylation of RNA polymerase II; generation of hypophosphorylated CTD of RNA polymerase II; generation of II(A) form of RNA polymerase II
Comment: This term was obsoleted because it represents a molecular function.
regulation of neutrophil mediated killing of bacterium (GO:0070950)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.
regulation of neutrophil mediated killing of fungus (GO:0070953)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.
negative regulation of neutrophil mediated killing of bacterium (GO:0070956)
Namespace: biological_process
Definition: Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.
Synonyms: down regulation of neutrophil mediated killing of bacterium; down-regulation of neutrophil mediated killing of bacterium; downregulation of neutrophil mediated killing of bacterium; inhibition of neutrophil mediated killing of bacterium
coenzyme F420 binding (GO:0070967)
Namespace: molecular_function
Definition: Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
pyrroloquinoline quinone binding (GO:0070968)
Namespace: molecular_function
Definition: Binding to pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.
Synonyms: PQQ binding
protein localization to endoplasmic reticulum (GO:0070972)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
Synonyms: protein localisation in endoplasmic reticulum; protein localization in endoplasmic reticulum; protein localization in ER
FHA domain binding (GO:0070975)
Namespace: molecular_function
Definition: Binding to a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.
Synonyms: Forkhead-associated domain binding
biphenyl catabolic process (GO:0070980)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
Synonyms: biphenyl breakdown; biphenyl catabolism; biphenyl degradation
demethylation (GO:0070988)
Namespace: biological_process
Definition: The process of removing one or more methyl groups from a molecule.
sensory perception of gravity (GO:0070998)
Namespace: biological_process
Definition: The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
U2-type catalytic step 2 spliceosome (GO:0071007)
Namespace: cellular_component
Definition: A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.
Synonyms: GT-AG catalytic step 2 spliceosome; major catalytic step 2 spliceosome; mammalian U2-type spliceosomal complex C; mammalian U2-type spliceosomal complex C1; yeast U2-type spliceosomal complex A2-2
U2-type post-spliceosomal complex (GO:0071021)
Namespace: cellular_component
Definition: A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.
Synonyms: GT-AG post-spliceosomal complex; major post-spliceosomal complex; mammalian U2-type spliceosomal complex C2; yeast U2-type spliceosomal complex A2-3
trans spliceosomal complex (GO:0071023)
Namespace: cellular_component
Definition: A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.
nuclear mRNA surveillance of mRNA 3'-end processing (GO:0071031)
Namespace: biological_process
Definition: The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.
Synonyms: nuclear mRNA catabolic process of mRNA with aberrant 3'-ends; nuclear mRNA quality control of mRNAs with aberrant 3'-ends
alpha3-beta1 integrin-CD151 complex (GO:0071058)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.
Synonyms: ITGA3-ITGB1-CD151 complex
alpha6-beta1 integrin-CD151 complex (GO:0071059)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.
Synonyms: ITGA6-ITGB1-CD151 complex
alpha6-beta4 integrin-CD151 complex (GO:0071061)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.
Synonyms: ITGA6-ITGB4-CD151 complex
alpha9-beta1 integrin-ADAM12 complex (GO:0071068)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.
Synonyms: ITGA9-ITGB1-ADAM12 complex
positive regulation of phospholipid biosynthetic process (GO:0071073)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
Synonyms: activation of phospholipid biosynthetic process; positive regulation of phospholipid anabolism; positive regulation of phospholipid biosynthesis; positive regulation of phospholipid formation; positive regulation of phospholipid synthesis; stimulation of phospholipid biosynthetic process; up regulation of phospholipid biosynthetic process; up-regulation of phospholipid biosynthetic process; upregulation of phospholipid biosynthetic process
obsolete RNA 3' uridylation (GO:0071076)
Namespace: biological_process
Definition: OBSOLETE. The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.
Comment: This term represents a molecular function
alpha3-beta1 integrin-basigin complex (GO:0071080)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.
Synonyms: ITGA3-ITGB1-BSG complex