LiteFold/GO huggingface dataset:
obsolete BMP signaling pathway involved in ureter morphogenesis (GO:0061149)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to its receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.
Synonyms: BMP signalling pathway involved in ureter morphogenesis
Comment: This term was obsoleted because it represents a GO-CAM model.
establishment of bipolar cell polarity (GO:0061171)
Namespace: biological_process
Definition: The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.
type Ib terminal bouton (GO:0061176)
Namespace: cellular_component
Definition: Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.
Synonyms: type Ib terminal button
regulation of dermatome development (GO:0061183)
Namespace: biological_process
Definition: Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
mesonephric glomerular mesangial cell development (GO:0061263)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.
mesonephric distal tubule morphogenesis (GO:0061273)
Namespace: biological_process
Definition: The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.
mesonephric capsule specification (GO:0061288)
Namespace: biological_process
Definition: The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
obsolete regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis (GO:0061295)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
Synonyms: regulation of mesenchymal stem cell apoptosis involved in mesonephric nephron morphogenesis; regulation of mesenchymal stem cell apoptotic process involved in mesonephric nephron morphogenesis
obsolete DNA strand renaturation involved in double-strand break repair (GO:0061306)
Namespace: biological_process
Definition: OBSOLETE. The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair.
Comment: This term was obsoleted because it represents a molecular function.
posterior Malpighian tubule development (GO:0061328)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.
epithelial cell proliferation involved in Malpighian tubule morphogenesis (GO:0061331)
Namespace: biological_process
Definition: The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.
obsolete planar cell polarity pathway involved in outflow tract morphogenesis (GO:0061347)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.
Comment: The reason for obsoletion is that this term should be captured using GO-CAM or extensions.
obsolete planar cell polarity pathway involved in pericardium morphogenesis (GO:0061354)
Namespace: biological_process
Definition: OBSOLETE. The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.
Comment: The reason for obsoletion is that this term should be captured using GO-CAM or extensions.
optic chiasma development (GO:0061360)
Namespace: biological_process
Definition: The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.
Synonyms: optic chiasm development
behavioral response to formalin induced pain (GO:0061368)
Namespace: biological_process
Definition: Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.
negative regulation of direction of cell growth (GO:0061391)
Namespace: biological_process
Definition: Any process that decreases the direction of cell growth.
obsolete positive regulation of transcription from RNA polymerase II promoter in response to hypoxia (GO:0061419)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter (GO:0061427)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.
Comment: This term was obsoleted because it represents a GO-CAM model.
positive regulation of transcription from RNA polymerase II promoter by oleic acid (GO:0061429)
Namespace: biological_process
Definition: Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
renal artery morphogenesis (GO:0061441)
Namespace: biological_process
Definition: The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.
obsolete integral component of muscle cell projection membrane (GO:0061455)
Namespace: cellular_component
Definition: OBSOLETE. The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Synonyms: integral to muscle cell projection membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
L-arginine transmembrane transporter activity (GO:0061459)
Namespace: molecular_function
Definition: Enables the transfer of L-arginine from one side of a membrane to the other.
Synonyms: arginine permease activity; arginine porter activity; arginine transmembrane transporter activity; arginine-importing ATPase activity; ATP-dependent L-arginine transmembrane transporter activity; ATPase-coupled L-arginine transmembrane transporter activity; histidine/arginine/lysine/ornithine porter activity; L-arginine transporter activity; L-arginine-importing ATPase activity
hematopoietic stem cell homeostasis (GO:0061484)
Namespace: biological_process
Definition: Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.
norepinephrine secretion, neurotransmission (GO:0061533)
Namespace: biological_process
Definition: The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.
Synonyms: noradrenaline secretion, neurotransmission
glutamate secretion, neurotransmission (GO:0061535)
Namespace: biological_process
Definition: The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.
histamine secretion, neurotransmission (GO:0061538)
Namespace: biological_process
Definition: The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.
tyramine secretion (GO:0061545)
Namespace: biological_process
Definition: The regulated release of a tyramine by a cell.
glycogen synthase activity, transferring glucose-1-phosphate (GO:0061547)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.
ganglion development (GO:0061548)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.
Synonyms: ganglia development; gangliogenesis
CMP phosphorylation (GO:0061566)
Namespace: biological_process
Definition: The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.
obsolete cyclic pyranopterin monophosphate synthase activity (GO:0061597)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction GTP = cyclic pyranopterin phosphate + diphosphate.
Comment: This term was made obsolete because it represents two distinct molecular functions.
molybdopterin adenylyltransferase activity (GO:0061598)
Namespace: molecular_function
Definition: Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
molybdopterin molybdotransferase activity (GO:0061599)
Namespace: molecular_function
Definition: Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
fructose-1-phosphate aldolase activity (GO:0061609)
Namespace: molecular_function
Definition: Catalysis of the reaction: beta-D-fructose-1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate.
glycerol catabolic process to glycerone phosphate (GO:0061610)
Namespace: biological_process
Definition: The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.
Synonyms: glycerol metabolism to DHAP; glycerol metabolism to dihydroxyacetone phosphate; glycerol metabolism to glycerone phosphate; glycerol to DHAP metabolic process; glycerol to dihydroxyacetone phosphate metabolic process
obsolete galactose to glucose-1-phosphate metabolic process (GO:0061612)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.
Comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using\nGO:0033499 name: galactose catabolic process via UDP-galactose
canonical glycolysis (GO:0061621)
Namespace: biological_process
Definition: The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
ubiquitin protein ligase activity (GO:0061630)
Namespace: molecular_function
Definition: Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S = X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
Synonyms: E3; ER-associated E3 ligase; protein ubiquitination activity; ubiquitin ligase activity
Comment: This enzyme catalyzes a transferase reaction.
Cdv-dependent cytokinesis (GO:0061639)
Namespace: biological_process
Definition: A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.
protein localization to CENP-A containing chromatin (GO:0061644)
Namespace: biological_process
Definition: Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.
tooth replacement (GO:0061648)
Namespace: biological_process
Definition: The process whose specific outcome is the replacement of an existing tooth with another tooth.
UFM1 ligase activity (GO:0061666)
Namespace: molecular_function
Definition: Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S = X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.
Synonyms: E3
RBL family protein binding (GO:0061675)
Namespace: molecular_function
Definition: Binding to a member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.
Synonyms: rhamnose-binding lectin family protein binding
alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity (GO:0061693)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.
obsolete methylglyoxal catabolic process to lactate (GO:0061727)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete single-stranded DNA-dependent GTPase activity (GO:0061746)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.
Comment: This term was obsoleted because there is no evidence that this reaction occurs under physiological conditions.
telomeric repeat-containing RNA binding (GO:0061752)
Namespace: molecular_function
Definition: Binding to long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.
Synonyms: TERRA binding
substrate localization to autophagosome (GO:0061753)
Namespace: biological_process
Definition: The localization process by which an autophagic substrate is delivered to a forming autophagosome.
Synonyms: substrate sequestration to autophagosome; substrate sequestration to phagophore
CAMKK-AMPK signaling cascade (GO:0061762)
Namespace: biological_process
Definition: The series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.
Synonyms: stress-activated AMP-activated protein kinase signaling cascade
obsolete intracellular chloride channel activity (GO:0061778)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
Comment: The reason for obsoletion is that this term represents a mix of a MF + a CC.
laminin-3B32 trimer (GO:0061801)
Namespace: cellular_component
Definition: A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.
Synonyms: laminin 3B32 complex; laminin-5B complex
mitotic spindle formation (spindle phase one) (GO:0061804)
Namespace: biological_process
Definition: The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
Synonyms: mitotic spindle elongation during mitotic prophase; mitotic spindle elongation during prophase; mitotic spindle elongation during prophase and prometaphase
positive regulation of DNA recombination at centromere (GO:0061807)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.
Synonyms: positive regulation of centromeric recombination
telomeric D-loop disassembly (GO:0061820)
Namespace: biological_process
Definition: A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
ventral surface of cell (GO:0061835)
Namespace: cellular_component
Definition: The surface of a migrating cell that is in contact with the substratum or cell layer.
neuron projection branch point (GO:0061845)
Namespace: cellular_component
Definition: The location where a secondary projection arises from a neuron projection.
obsolete negative regulation of histone H3-S10 phosphorylation (GO:0061866)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to histone H3 on a serine residue at position 10.
Comment: This term was obsoleted because it represents a molecular function.
regulation of hepatic stellate cell migration (GO:0061869)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.
positive regulation of astrocyte activation (GO:0061890)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of astrocyte activation.
leading edge of dendritic growth cone (GO:0061917)
Namespace: cellular_component
Definition: That part of the dendritic growth cone which represents the distal part of the structure.
Synonyms: dendritic growth cone leading edge; distal tip of dendritic growth cone
process utilizing autophagic mechanism (GO:0061919)
Namespace: biological_process
Definition: A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway.
histone propionyltransferase activity (GO:0061922)
Namespace: molecular_function
Definition: Catalysis of the reaction: propionyl-CoA + histone = CoA + propionyl-histone.
regulation of erythrocyte enucleation (GO:0061930)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of erythrocyte enucleation.
c-di-GMP signaling (GO:0061939)
Namespace: biological_process
Definition: Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.
Synonyms: 3',5'-cyclic di-GMP signaling; cyclic di-(3':5')-guanosine monophosphate signaling; cyclic di-GMP signaling; cyclic diguanylate signaling
regulation of c-di-GMP signaling (GO:0061940)
Namespace: biological_process
Definition: Any process that modulates the rate frequency or extent of c-di-GMP signaling.
premature acrosome loss (GO:0061948)
Namespace: biological_process
Definition: The discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.
Synonyms: spontaneous acrosome loss
Comment: If the release of the acrosome content when the sperm reaches to the zona pellucida, consider using acrosome reaction.
response to (R)-carnitine (GO:0061959)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an (R)-carnitine stimulus.
Synonyms: response to L-carnitine
obsolete positive regulation of heme oxygenase activity (GO:0061961)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency or rate of heme oxygenase activity.
Comment: This term was obsoleted because it represents a molecular function.
temporomandibular joint articular cartilage development (GO:0061976)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.
meiosis II cell cycle process (GO:0061983)
Namespace: biological_process
Definition: A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes.
Synonyms: second meiotic division
regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0062025)
Namespace: biological_process
Definition: Any process that modualtes the rate, frequency or extent of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
positive regulation of stress granule assembly (GO:0062029)
Namespace: biological_process
Definition: Any process that starts or increases the rate, frequency or extent of stress-granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
biofilm matrix (GO:0062039)
Namespace: cellular_component
Definition: A type of extracellular matrix that surrounds the cells within a microbial biofilm. The matrix is composed of extracellular polymeric substances including exopolysaccharides, proteins, nucleic acids, lipids, and other biomolecules.
positive regulation of meiotic sister chromatid arm separation (GO:0062041)
Namespace: biological_process
Definition: Any process that increases the rate or extent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
fluoride channel activity (GO:0062054)
Namespace: molecular_function
Definition: Enables the energy-independent facilitated diffusion of a fluoride ion through a transmembrane aqueous pore or channel.
PSII associated light-harvesting complex II binding (GO:0062066)
Namespace: molecular_function
Definition: Binding to a PSII associated light-harvesting complex II.