LiteFold/GO huggingface dataset:
obsolete intrinsic component of postsynaptic specialization membrane (GO:0098948)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to postsynaptic specialization membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete intrinsic component of dense core granule membrane (GO:0098956)
Namespace: cellular_component
Definition: OBSOLETE. The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
Synonyms: intrinsic to dense core granule membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
neuron to neuron synapse (GO:0098984)
Namespace: cellular_component
Definition: A synapse in which pre and post-synaptic cells are neurons.
symbiont entry into host cell via disruption of host cell envelope lipopolysaccharide (GO:0098995)
Namespace: biological_process
Definition: The disruption by a symbiont of host cell wall lipopolysaccharides to allow entry into the host cell. For example a phage entering a Gram-negative bacterium may actively break down outer membrane lipopolysaccharides.
Synonyms: degradation of host cell envelope lipopolysaccharide during viral entry; degradation of host lipopolysaccharide during virus entry; disassembly by virus of outer membrane lipopolysaccharide during viral entry; disruption by virus of host envelope lipopolysaccharide during virus entry
obsolete anchored component of postynaptic endocytic zone membrane (GO:0099028)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete anchored component of postsynaptic endosome membrane (GO:0099034)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
ceramide translocation (GO:0099040)
Namespace: biological_process
Definition: The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.
vesicle tethering to Golgi (GO:0099041)
Namespace: biological_process
Definition: The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
clearance of foreign intracellular RNA (GO:0099047)
Namespace: biological_process
Definition: A defense process that protects an organism from invading foreign RNA.
obsolete activating signal cointegrator 1 complex (GO:0099053)
Namespace: cellular_component
Definition: OBSOLETE. A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.
Synonyms: ASC-1 complex
Comment: The reason for obsoletion is that this term is equivalent to GO:0180022 RQC-trigger complex.
obsolete integral component of postsynaptic endosome membrane (GO:0099064)
Namespace: cellular_component
Definition: OBSOLETE. The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
obsolete integral component of spine apparatus membrane (GO:0099065)
Namespace: cellular_component
Definition: OBSOLETE. The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
dynamic microtubule bundle (GO:0099071)
Namespace: cellular_component
Definition: A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.
mitochondrion to peroxisome vesicle-mediated transport (GO:0099076)
Namespace: biological_process
Definition: Vesicle-mediated transport of cargo from the mitochondrion to the peroxisome, mediated by a mitochondrion-derived vesicle.
Synonyms: mitochondrion to peroxisome transport
actin body (GO:0099079)
Namespace: cellular_component
Definition: An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.
ligand-gated monoatomic cation channel activity (GO:0099094)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
Synonyms: ligand-gated cation channel activity
G-protein gated monoatomic ion channel activity (GO:0099099)
Namespace: molecular_function
Definition: An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.
Synonyms: G-protein gated ion channel activity
microtubule polymerization based protein transport (GO:0099112)
Namespace: biological_process
Definition: The transport of a protein driven by polymerization of a microtubule to which it is attached.
fungal sorus development (GO:0099121)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.
regulation of synaptic vesicle docking (GO:0099148)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of synaptic vesicle docking.
regulation of postsynaptic density assembly (GO:0099151)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of postsynaptic density assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic density.
presynapse organization (GO:0099172)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse.
Synonyms: presynapse development; presynapse morphogenesis; presynapse organisation; presynapse organization and biogenesis
regulation of postsynapse organization (GO:0099175)
Namespace: biological_process
Definition: Any process that modulates the physical form of a postsynapse.
Synonyms: regulation of postsynapse organisation; regulation of postsynapse organization and biogenesis; regulation of postsynapse structure
maintenance of mitotic sister chromatid cohesion, telomeric (GO:0099403)
Namespace: biological_process
Definition: The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
Synonyms: maintenance of mitotic sister chromatin cohesion at telomere; maintenance of sister chromatin cohesion at telomere at mitosis; maintenance of telomeric mitotic sister chromatin cohesion
obsolete monoatomic ion antiporter activity involved in regulation of presynaptic membrane potential (GO:0099520)
Namespace: molecular_function
Definition: OBSOLETE. Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
Synonyms: ion antiporter activity involved in regulation of pre-synaptic membrane potential; ion antiporter activity involved in regulation of presynaptic membrane potential
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
perisynaptic space (GO:0099544)
Namespace: cellular_component
Definition: The extracellular region immediately adjacent to to a synapse.
Synonyms: extrasynaptic space
regulation of translation at synapse, modulating synaptic transmission (GO:0099547)
Namespace: biological_process
Definition: Any process that modulates synaptic transmission by regulating translation occurring at the synapse.
Comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
regulation of protein catabolic process at postsynapse, modulating synaptic transmission (GO:0099576)
Namespace: biological_process
Definition: Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.
Comment: Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua.
protein localization to spore cell wall (GO:0099614)
Namespace: biological_process
Definition: A process in which a protein is transported, tethered to or otherwise maintained in a spore cell wall.
Synonyms: protein targeting to spore cell wall
(R)-2-hydroxyglutarate-pyruvate transhydrogenase activity (GO:0099615)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = (R)-lactate + 2-oxoglutarate.
Synonyms: (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity; D-2HG-pyruvate transhydrogenase activity; R-2-hydroxyglutarate alpha-pyruvate transhydrogenase activity
obsolete positive regulation of peroxisome organization by transcription from RNA polymerase II promoter (GO:0100004)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates peroxisome organization.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter (GO:0100028)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter (GO:0100033)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter (GO:0100054)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that positively regulates flocculation via cell wall protein-carbohydrate interaction.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of phenotypic switching by transcription from RNA polymerase II promoter (GO:0100057)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates phenotypic switching.
Comment: This term was obsoleted because it represents a GO-CAM model.
obsolete regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter (GO:0100063)
Namespace: biological_process
Definition: OBSOLETE. Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport.
Comment: The term was obsoleted because it is better represented by a GO-CAM model.
ficolin-1-rich granule membrane (GO:0101003)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a ficolin-1-rich granule.
pulmonary blood vessel remodeling (GO:0101010)
Namespace: biological_process
Definition: The reorganization or renovation of existing pulmonary blood vessels.
Synonyms: pulmonary blood vessel remodelling
mechanosensitive voltage-gated sodium channel activity (GO:0101013)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms: mechanically-modulated voltage-gated sodium channel activity
protein folding chaperone complex (GO:0101031)
Namespace: cellular_component
Definition: A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.
Synonyms: chaperone complex
Comment: An example of this is HSP90AB1 in human (P08238) in PMID:21855797 (inferred from direct assay).
proline dipeptidase activity (GO:0102009)
Namespace: molecular_function
Definition: Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal = L-proline + a standard alpha amino acid.
obsolete (-)-jasmonoyl-isoleucine synthetase activity (GO:0102053)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) = H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid.
Comment: This term was obsoleted because it represents a specific substrate of jasmonate-amino synthetase activity ; GO:0080123.
endo-alpha-bergamotene synthase activity (GO:0102060)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate = (-)-endo-alpha-bergamotene + diphosphoric acid.
Synonyms: endo-alpha-bergamontene synthase activity
obsolete 9,10-epoxy-18-hydroxystearate hydrolase activity (GO:0102071)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O = 9,10,18-trihydroxystearate.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
obsolete acrylate:acyl-coA CoA transferase activity (GO:0102093)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: acryloyl-CoA + H2O = acrylate + coenzyme A + H+.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
decaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate:dTDP-alpha-L-rhamnose rhamnosyltransferase activity (GO:0102096)
Namespace: molecular_function
Definition: Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol = dTDP(3-) + alpha-L-Rhap-(1->3)-alpha-D-GlcpNAc-1-diphospho-trans,octacis-decaprenol + H+.
8-oxoguanine deaminase activity (GO:0102127)
Namespace: molecular_function
Definition: Catalysis of the reaction: H+ + 7,8-dihydro-8-oxoguanine + H2O = 7,9-dihydro-1H-purine-2,6,8(3H)-trione + ammonium.
obsolete (22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity (GO:0102135)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 = (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.
Comment: This term was obsoleted because it represents a specific substrate.
obsolete N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity (GO:0102200)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: H2O + an N-acylphosphatidylethanolamine = H+ + an N-acylethanolamine + a 1,2-diacyl-sn-glycerol 3-phosphate.
Comment: This term was obsoleted because it represents the same activity as N-acylphosphatidylethanolamine-specific phospholipase D activity , GO:0070290.
obsolete amylopectin maltohydrolase activity (GO:0102229)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: n H2O + an exposed unphosphorylated, unbranched malto-oligosaccharide tail on amylopectin = amylopectin + maltose.
Comment: This term was obsoleted because it represents a specific substrate of beta-amylase activity ; GO:0016161.
obsolete crotonaldehyde redutase activity (GO:0102233)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ = butanal + NADP.
Comment: The reason for obsoletion is that a leaf term should not refer to partial EC.
tRNA-dihydrouridine20a synthase activity (GO:0102266)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) = H+ + a uracil20a in tRNA + NAD(P)H.
obsolete 3-ketodihydrosphinganine (C18) reductase activity (GO:0102282)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: NAD(1-) + a sphinganine = 3-dehydrosphinganinium(1+) + NADH + H+.
Comment: This term was obsoleted because there is no evidence that this reaction exists.
obsolete 11alpha-hydroxy-beta-amyrin dehydrogenase activity (GO:0102291)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ = 11-oxo-beta-amyrin + 2 H2O + NADP.
Comment: This term was obsoleted because it is a subreaction of beta-amyrin 11-oxidase activity ; GO:0102289.
obsolete selenocystathione synthase activity (GO:0102298)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: L-selenocysteine + O-phosphonato-L-homoserine = hydrogenphosphate + L-selenocystathionine.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
4-methylaminobutyrate oxidase (demethylating) activity (GO:0102317)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4-(methylamino)butanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2.
obsolete 2-hydroxy-6-oxo-nona-2,4-dienoate hydrolase activity (GO:0102324)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-hydroxy-6-oxo-nona-2,4-dienoate + H2O = butyrate + 2-oxopent-4-enoate + H+.
Comment: This term was obsoleted because it represents a specific substrate of 2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity ; GO:0018774.
2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity (GO:0102355)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O = 3-maleylpyruvate + H+.
obsolete esculetin 4-O-beta-glucosyltransferase activity (GO:0102361)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: esculetin + UDP-alpha-D-glucose = 4-O-beta-D-glucosyl-esculetin + UDP + H+.
Comment: This term was obsoleted because it represents a specific substrate of hydroxycinnamate 4-beta-glucosyltransferase activity ; GO:0047218.
obsolete isoscopoletin-O-methyltransferase activity (GO:0102363)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine = scoparone + S-adenosyl-L-homocysteine + H+.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
obsolete beta-amyrin 30-monooxygenase activity (GO:0102368)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 = 30-hydroxy-beta-amyrin + NADP + H2O.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
obsolete betulin dehydrogenase activity (GO:0102371)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 = betulinic aldehyde + NADP(3-) + 2 H2O.
Comment: This term was obsoleted because it is not known to be catalyzed by any gene product.
steviolmonoside glucosyltransferase activity (GO:0102378)
Namespace: molecular_function
Definition: Catalysis of the reaction: steviolmonoside + UDP-alpha-D-glucose = rubusoside + UDP.
steviolbioside glucosyltransferase activity (rebaudioside B forming) (GO:0102380)
Namespace: molecular_function
Definition: Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = H+ + rebaudioside B + UDP.
phenylacetaldehyde reductase activity (GO:0102386)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-phenylacetaldehyde + NADPH + H+ = 2-phenylethanol + NADP+.
mycophenolic acid acyl-glucuronide esterase activity (GO:0102390)
Namespace: molecular_function
Definition: Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O = mycophenolate + H+ + D-glucopyranuronate.
decanoate-CoA ligase activity (GO:0102391)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + decanoate + CoA = AMP + diphosphate + decanoyl-CoA.
obsolete 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity (GO:0102402)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-phenylethyl 6-O-beta-D-xylopyranosyl-beta-D-glucopyranoside + H2O = 2-phenylethanol + 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose.
Comment: This term was obsoleted because it represents a specific substrate of beta-primeverosidase activity ; GO:0050535.
obsolete quercetin-3,4'-O-glucosyltransferase activity (GO:0102411)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) = quercetin 3,4'-O-diglucoside + UDP(3-).
Comment: This term was obsoleted because it represents a specific substrate.
obsolete apigenin-7-O-glucoside 1,6-glucosyltransferase activity (GO:0102417)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose = apigenin-7-O-gentiobioside + UDP + H+.
Comment: This term was obsoleted because it represents a specific substrate.
obsolete sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity (GO:0102424)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose = (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+.
Comment: This term was obsoleted because it represents a specific substrate.
obsolete kaempferol-3-O-glucoside 1,6-glucosyltransferase activity (GO:0102428)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose = kaempferol-3-gentiobioside + UDP.
Comment: This term was obsoleted because it represents a specific substrate.
pterin-4alpha-carbinolamine dehydratase activity (GO:0102434)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.
3-methylquercetin 3'-O-methyltransferase activity (GO:0102445)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine = 3,3'-O-dimethylquercetin + H+ + S-adenosyl-L-homocysteine.