LiteFold/GO huggingface dataset:
positive regulation of neutrophil differentiation (GO:0045660)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.
Synonyms: activation of neutrophil differentiation; stimulation of neutrophil differentiation; up regulation of neutrophil differentiation; up-regulation of neutrophil differentiation; upregulation of neutrophil differentiation
positive regulation of embryo sac central cell differentiation (GO:0045693)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.
Synonyms: activation of female gametophyte central cell differentiation; positive regulation of female gametophyte central cell differentiation; stimulation of female gametophyte central cell differentiation; up regulation of female gametophyte central cell differentiation; up-regulation of female gametophyte central cell differentiation; upregulation of female gametophyte central cell differentiation
negative regulation of salivary gland boundary specification (GO:0045705)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.
Synonyms: down regulation of salivary gland determination; down-regulation of salivary gland determination; downregulation of salivary gland determination; inhibition of salivary gland determination; negative regulation of salivary gland determination
obsolete positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.
Synonyms: activation of epidermal growth factor receptor activity; positive regulation of EGF receptor activity; positive regulation of EGFR activity; positive regulation of epidermal growth factor receptor activity; stimulation of epidermal growth factor receptor activity; up regulation of epidermal growth factor receptor activity; up-regulation of epidermal growth factor receptor activity; upregulation of epidermal growth factor receptor activity
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
obsolete regulation of anti-apoptosis (GO:0045767)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of anti-apoptosis.
Synonyms: regulation of anti-apoptosis
Comment: This term was made obsolete because it was ill-defined.
positive regulation of asymmetric cell division (GO:0045770)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of asymmetric cell division.
Synonyms: activation of asymmetric cell division; stimulation of asymmetric cell division; up regulation of asymmetric cell division; up-regulation of asymmetric cell division; upregulation of asymmetric cell division
positive regulation of blood pressure (GO:0045777)
Namespace: biological_process
Definition: Any process in which the force of blood traveling through the circulatory system is increased.
Synonyms: activation of blood pressure; stimulation of blood pressure; up regulation of blood pressure; up-regulation of blood pressure; upregulation of blood pressure
negative regulation of cell budding (GO:0045781)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.
Synonyms: down regulation of cell budding; down-regulation of cell budding; downregulation of cell budding; inhibition of cell budding; negative regulation of budding
obsolete positive regulation of calcium in ER (GO:0045784)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the concentration of calcium in the ER.
Synonyms: positive regulation of calcium in ER
Comment: This term was made obsolete because the term name is ambiguous and as a result, the term was incorrectly placed in the ontology (it was a descendant of 'protein transport').
positive regulation of cell size (GO:0045793)
Namespace: biological_process
Definition: Any process that increases cell size.
Synonyms: activation of cell size; stimulation of cell size; up regulation of cell size; up-regulation of cell size; upregulation of cell size
negative regulation of eclosion (GO:0045804)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.
Synonyms: down regulation of eclosion; down-regulation of eclosion; downregulation of eclosion; inhibition of eclosion
positive regulation of endocytosis (GO:0045807)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of endocytosis.
Synonyms: activation of endocytosis; stimulation of endocytosis; up regulation of endocytosis; up-regulation of endocytosis; upregulation of endocytosis
positive regulation of isotype switching (GO:0045830)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of isotype switching.
Synonyms: activation of isotype switching; positive regulation of class switch recombination; positive regulation of class switching; positive regulation of isotype switch recombination; stimulation of isotype switching; up regulation of isotype switching; up-regulation of isotype switching; upregulation of isotype switching
negative regulation of mitotic nuclear division (GO:0045839)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
Synonyms: down regulation of mitosis; down-regulation of mitosis; downregulation of mitosis; inhibition of mitosis; negative regulation of mitosis
obsolete negative regulation of molecular function, epigenetic (GO:0045857)
Namespace: biological_process
Definition: OBSOLETE. Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.
Synonyms: down regulation of protein activity, epigenetic; down-regulation of protein activity, epigenetic; downregulation of protein activity, epigenetic; inhibition of protein activity, epigenetic; negative regulation of protein activity, epigenetic
Comment: This term was obsoleted because it is not an active process.
regulation of protein kinase activity (GO:0045859)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of protein kinase activity.
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045869)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
Synonyms: down regulation of retroviral genome replication; down-regulation of retroviral genome replication; downregulation of retroviral genome replication; inhibition of retroviral genome replication; negative regulation of retroviral genome replication; regulation of retroviral genome replication
obsolete negative regulation of rhodopsin gene expression (GO:0045871)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression.
Synonyms: down regulation of rhodopsin gene activity; down-regulation of rhodopsin gene activity; downregulation of rhodopsin gene activity; inhibition of rhodopsin gene activity; negative regulation of rhodopsin gene activity
Comment: This term was obsoleted because it refers to a specific gene product. The gene product should be captured as an annotation extension using 'has input'.
obsolete positive regulation of transcription of homeotic gene (Polycomb group) (GO:0045889)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription of homeotic genes of the Polycomb group.
Synonyms: positive regulation of transcription of homeotic gene (Polycomb group)
Comment: This term was made obsolete because it relates to a specific gene family rather than a process.
obsolete regulation of transcription of homeotic gene (trithorax group) (GO:0045890)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription of homeotic genes of the trithorax group.
Synonyms: regulation of transcription of homeotic gene (trithorax group)
Comment: This term was made obsolete because it relates to a specific gene family rather than a process.
positive regulation of DNA-templated transcription (GO:0045893)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
Synonyms: activation of gene-specific transcription; activation of transcription, DNA-dependent; positive regulation of cellular transcription, DNA-dependent; positive regulation of gene-specific transcription; positive regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-templated; stimulation of gene-specific transcription; stimulation of transcription, DNA-dependent; transcription activator activity; up regulation of gene-specific transcription; up regulation of transcription, DNA-dependent; up-regulation of gene-specific transcription; up-regulation of transcription, DNA-dependent; upregulation of gene-specific transcription; upregulation of transcription, DNA-dependent
obsolete positive regulation of transcription during mitotic cell cycle (GO:0045897)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
Synonyms: activation of transcription during mitosis; mitotic activation of transcription; positive regulation of transcription, mitotic; stimulation of transcription during mitosis; up regulation of transcription during mitosis; up-regulation of transcription during mitosis; upregulation of transcription during mitosis
Comment: The reason for obsoletion is that 'during' should be captured using an annotation extension.
negative regulation of translational fidelity (GO:0045902)
Namespace: biological_process
Definition: Any process that decreases the ability of the translational apparatus to interpret the genetic code.
Synonyms: down regulation of translational fidelity; down-regulation of translational fidelity; downregulation of translational fidelity; inhibition of translational fidelity
positive regulation of DNA recombination (GO:0045911)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of DNA recombination.
Synonyms: activation of DNA recombination; stimulation of DNA recombination; up regulation of DNA recombination; up-regulation of DNA recombination; upregulation of DNA recombination
negative regulation of exocytosis (GO:0045920)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
Synonyms: down regulation of exocytosis; down-regulation of exocytosis; downregulation of exocytosis; inhibition of exocytosis
positive regulation of exocytosis (GO:0045921)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of exocytosis.
Synonyms: activation of exocytosis; stimulation of exocytosis; up regulation of exocytosis; up-regulation of exocytosis; upregulation of exocytosis
negative regulation of growth (GO:0045926)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
Synonyms: down regulation of growth; down-regulation of growth; downregulation of growth; inhibition of growth
positive regulation of mitotic cell cycle (GO:0045931)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
Synonyms: activation of progression through mitotic cell cycle; positive regulation of mitotic cell cycle progression; positive regulation of progression through mitotic cell cycle; stimulation of progression through mitotic cell cycle; up regulation of progression through mitotic cell cycle; up-regulation of progression through mitotic cell cycle; upregulation of progression through mitotic cell cycle
positive regulation of transcription by RNA polymerase II (GO:0045944)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: activation of global transcription from RNA polymerase II promoter; activation of transcription from RNA polymerase II promoter; positive regulation of gene-specific transcription from RNA polymerase II promoter; positive regulation of global transcription from Pol II promoter; positive regulation of transcription from Pol II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter, global; stimulation of global transcription from RNA polymerase II promoter; stimulation of transcription from RNA polymerase II promoter; up regulation of global transcription from RNA polymerase II promoter; up regulation of transcription from RNA polymerase II promoter; up-regulation of global transcription from RNA polymerase II promoter; up-regulation of transcription from RNA polymerase II promoter; upregulation of global transcription from RNA polymerase II promoter; upregulation of transcription from RNA polymerase II promoter
positive regulation of translational initiation (GO:0045948)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of translational initiation.
Synonyms: activation of translational initiation; stimulation of translational initiation; up regulation of translational initiation; up-regulation of translational initiation; upregulation of translational initiation
negative regulation of dopamine metabolic process (GO:0045963)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
Synonyms: down regulation of dopamine metabolic process; down-regulation of dopamine metabolic process; downregulation of dopamine metabolic process; inhibition of dopamine metabolic process; negative regulation of dopamine metabolism
positive regulation of purine nucleobase metabolic process (GO:0045983)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.
Synonyms: activation of purine base metabolic process; positive regulation of purine base metabolic process; positive regulation of purine base metabolism; stimulation of purine base metabolic process; up regulation of purine base metabolic process; up-regulation of purine base metabolic process; upregulation of purine base metabolic process
positive regulation of pyrimidine nucleobase metabolic process (GO:0045985)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
Synonyms: activation of pyrimidine base metabolic process; positive regulation of pyrimidine base metabolic process; positive regulation of pyrimidine base metabolism; stimulation of pyrimidine base metabolic process; up regulation of pyrimidine base metabolic process; up-regulation of pyrimidine base metabolic process; upregulation of pyrimidine base metabolic process
IMP metabolic process (GO:0046040)
Namespace: biological_process
Definition: The chemical reactions and pathways involving IMP, inosine monophosphate.
Synonyms: IMP metabolism
TMP metabolic process (GO:0046044)
Namespace: biological_process
Definition: The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.
Synonyms: TMP metabolism
dGMP metabolic process (GO:0046054)
Namespace: biological_process
Definition: The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
Synonyms: dGMP metabolism
dTMP metabolic process (GO:0046073)
Namespace: biological_process
Definition: The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
Synonyms: dTMP metabolism
dTMP catabolic process (GO:0046074)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.
Synonyms: dTMP breakdown; dTMP catabolism; dTMP degradation
adenine metabolic process (GO:0046083)
Namespace: biological_process
Definition: The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
Synonyms: adenine metabolism
adenine biosynthetic process (GO:0046084)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
Synonyms: adenine anabolism; adenine biosynthesis; adenine formation; adenine synthesis
deoxyuridine metabolic process (GO:0046096)
Namespace: biological_process
Definition: The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
Synonyms: deoxyuridine metabolism
hypoxanthine biosynthetic process (GO:0046101)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
Synonyms: hypoxanthine anabolism; hypoxanthine biosynthesis; hypoxanthine formation; hypoxanthine synthesis
obsolete D-alanine family amino acid biosynthetic process (GO:0046145)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids.
Synonyms: D-alanine family amino acid anabolism; D-alanine family amino acid biosynthesis; D-alanine family amino acid formation; D-alanine family amino acid synthesis
Comment: This term was obsoleted because it represents an unnecessary grouping class.
tetrahydrobiopterin catabolic process (GO:0046147)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
Synonyms: 5,6,7,8-tetrahydrobiopterin catabolic process; tetrahydrobiopterin breakdown; tetrahydrobiopterin catabolism; tetrahydrobiopterin degradation
melanin catabolic process (GO:0046150)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
Synonyms: melanin breakdown; melanin catabolism; melanin degradation
ommochrome catabolic process (GO:0046153)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
Synonyms: ommochrome breakdown; ommochrome catabolism; ommochrome degradation
rhodopsin metabolic process (GO:0046154)
Namespace: biological_process
Definition: The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
Synonyms: rhodopsin metabolism
ocellus pigment catabolic process (GO:0046159)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
Synonyms: ocellus pigment breakdown; ocellus pigment catabolism; ocellus pigment degradation
octanol biosynthetic process (GO:0046171)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.
Synonyms: octanol anabolism; octanol biosynthesis; octanol formation; octanol synthesis
acetaldehyde catabolic process (GO:0046187)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
Synonyms: acetaldehyde breakdown; acetaldehyde catabolism; acetaldehyde degradation
phenol-containing compound biosynthetic process (GO:0046189)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
Synonyms: phenol-containing compound anabolism; phenol-containing compound biosynthesis; phenol-containing compound formation; phenol-containing compound synthesis
aerobic phenol-containing compound catabolic process (GO:0046191)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
Synonyms: aerobic phenol-containing compound breakdown; aerobic phenol-containing compound catabolism; aerobic phenol-containing compound degradation
obsolete 4-nitrophenol biosynthetic process (GO:0046195)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
Synonyms: 4-nitrophenol anabolism; 4-nitrophenol biosynthesis; 4-nitrophenol biosynthetic process; 4-nitrophenol formation; 4-nitrophenol synthesis
Comment: This term was made obsolete because 4-nitrophenol is not synthesized by living organisms, and GO does not cover non-biological processes.