LiteFold/GO huggingface dataset:
NAD+-protein-arginine ADP-ribosyltransferase activity (GO:0106274)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-arginyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide.
Synonyms: ADP-ribosyltransferase activity; mono(ADP-ribosyl)transferase activity; NAD(+):L-arginine ADP-D-ribosyltransferase activity; NAD(P)(+)--arginine ADP-ribosyltransferase activity; NAD(P)+-protein-arginine ADP-ribosyltransferase activity; NAD(P)+:L-arginine ADP-D-ribosyltransferase activity; NAD(P)+:protein-L-arginine ADP-D-ribosyltransferase activity; NADP+-protein-arginine ADP-ribosyltransferase activity; peptidyl-arginine ADP-ribosylation activity; protein-arginine ADP-ribosyltransferase activity
positive regulation of UDP-N-acetylglucosamine biosynthetic process (GO:0106280)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.
Synonyms: positive egulation of UDP-N-acetylglucosamine formation; positive regulation of UDP-GlcNAc biosynthetic process; positive regulation of UDP-N-acetylglucosamine anabolism; positive regulation of UDP-N-acetylglucosamine biosynthesis; positive regulation of UDP-N-acetylglucosamine synthesis
methylenetetrahydrofolate reductase (NADH) activity (GO:0106312)
Namespace: molecular_function
Definition: Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H+.
methylenetetrahydrofolate reductase (NADPH) activity (GO:0106313)
Namespace: molecular_function
Definition: Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP+ = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADPH + H+.
obsolete (S)-limonene 1,2-monooxygenase NADPH activity (GO:0106323)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: (4S)-limonene + NADPH+= + H+ + O2 = NADP+ + H2O + (4S)-limonene-1,2-epoxide.
Comment: This term was obsoleted because it represents a specific substrate of limonene 1,2-monooxygenase activity ; GO:0052601.
ds/ssDNA junction-specific dsDNA endonuclease activity (GO:0106332)
Namespace: molecular_function
Definition: Catalysis of the endonucleolytic cleavage of double-stranded DNA near a double-strand/single-strand DNA junction.
tRNA (cytidine(32)-2'-O-ribose)-methyltransferase activity (GO:0106339)
Namespace: molecular_function
Definition: Catalysis of the reaction: cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + S-adenosyl-L-homocysteine + H+.
Synonyms: tRNA (cytidine 32-2'-O)-methyltransferase activity; tRNA (cytidine(32)-2'-O)-methyltransferase activity
glutarate dioxygenase activity (GO:0106343)
Namespace: molecular_function
Definition: Catalysis of the reaction glutarate + 2-oxoglutarate + O2 = (S)-2-hydroxyglutarate + succinate + CO2.
purine deoxyribonucleotide salvage (GO:0106381)
Namespace: biological_process
Definition: Any process which produces a purine deoxyribonucleotide from derivatives of it, without de novo synthesis.
(3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity (GO:0106386)
Namespace: molecular_function
Definition: Catalysis of the reaction: a (3R)-3-hydroxyacyl-CoA + NAD+ = a 3-oxoacyl-CoA + NADH + H+.
Synonyms: (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity; (3R)-hydroxyacyl-CoA dehydrogenase (NAD+) activity
diadenylate cyclase activity (GO:0106408)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2 ATP = 3',3'-c-di-AMP + 2 diphosphate.
Synonyms: cyclic-di-AMP synthase
obsolete XMP 5'-nucleosidase activity (GO:0106411)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 5'XMP + H20 = phosphate + xanthosine.
Comment: The reason for obsoletion is that it is more specific than the specificity of any known gene product.
UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity (GO:0106418)
Namespace: molecular_function
Definition: Catalysis of the reaction: ATP + UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate.
Synonyms: murein peptide ligase
carotenoid isomerooxygenase activity (GO:0106422)
Namespace: molecular_function
Definition: Catalysis of the reaction: Zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal.
N6-methyl-(d)ATP hydrolase activity (GO:0106431)
Namespace: molecular_function
Definition: Catalysis of the reaction N6-methyl-(d)ATP + H2O = N6-methyl-(d)AMP + diphosphate + H+.
obsolete ncRNA deadenylation (GO:0110008)
Namespace: biological_process
Definition: OBSOLETE. Shortening of the poly(A) tail of a nuclear-transcribed ncRNA.
Comment: The reason for obsoletion is that this term represents a molecular function.
positive regulation of elastin catabolic process (GO:0110015)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
cap-independent translational initiation of linear mRNA (GO:0110017)
Namespace: biological_process
Definition: The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate linear mRNA translation.
DNA strand resection involved in replication fork processing (GO:0110025)
Namespace: biological_process
Definition: The 5' to 3' exonucleolytic resection of DNA at the site of a stalled replication fork that contributes to replication fork processing.
regulation of nematode pharynx morphogenesis (GO:0110041)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of nematode pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.
positive regulation of nematode pharynx morphogenesis (GO:0110043)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of nematode pharynx morphogenesis.
obsolete signal transduction involved in cell cycle switching, mitotic to meiotic cell cycle (GO:0110046)
Namespace: biological_process
Definition: OBSOLETE. A signal transduction process that contributes to cell cycle switching, mitotic to meiotic cell cycle.
Comment: The reason for obsoletion is that this term represents a mix of different pathways.
positive regulation of actin filament annealing (GO:0110056)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.
negative regulation of ferroptosis (GO:0110076)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of ferroptosis.
regulation of placenta blood vessel development (GO:0110079)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of placenta blood vessel development.
negative regulation of hippocampal neuron apoptotic process (GO:0110091)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.
positive regulation of imaginal disc-derived wing vein specification (GO:0110108)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of imaginal disc-derived wing vein specification.
obsolete regulation of lipid transporter activity (GO:0110112)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate, or extent of lipid transporter activity.
Comment: This term was obsoleted because it represents a molecular function.
obsolete positive regulation of lipid transporter activity (GO:0110113)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate, or extent of lipid transporter activity.
Comment: This term was obsoleted because it represents a molecular function.
regulation of compound eye photoreceptor cell differentiation (GO:0110116)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.
gamma-tubulin complex localization to nuclear side of mitotic spindle pole body (GO:0110120)
Namespace: biological_process
Definition: Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the nuclear side of the mitotic spindle pole body.
Norrin signaling pathway (GO:0110135)
Namespace: biological_process
Definition: The series of molecular signals initiated by binding of the cysteine knot protein Norrin to a Frizzled 4 (Fzd4) family receptor on the surface of the target cell and ending with a change in cell state.
regulation of imaginal disc-derived leg joint morphogenesis (GO:0110137)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.
obsolete biomineralization (GO:0110148)
Namespace: biological_process
Definition: OBSOLETE. The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products.
Synonyms: biomineral formation; biomineralisation; mineralisation; mineralization
Comment: This term was obsoleted because it grouped multicellular organism processes and cellular processes.
positive regulation of mitotic spindle formation (spindle phase one) (GO:0110161)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).
apical plasma membrane urothelial plaque (GO:0120001)
Namespace: cellular_component
Definition: A scallop-shaped plaque, also referred to as an asymmetric unit membrane (AUM), found in the apical plasma membrane of urothelial superficial (umbrella) cells which form a a barrier to the passage of water and soluble toxic compounds found in urine. The plaques are thickened regions of membrane composed of uroplakin transmembrane proteins which form a crystalline array.
Synonyms: asymmetric unit membrane; AUM
phosphatidylcholine transfer activity (GO:0120019)
Namespace: molecular_function
Definition: Removes phosphatidylcholine from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: intermembrane phosphatidylcholine transfer activity; phosphatidylcholine carrier activity
cholesterol transfer activity (GO:0120020)
Namespace: molecular_function
Definition: Removes cholesterol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.
Synonyms: cholesterol carrier activity; cholesterol transporter activity; intermembrane cholesterol transfer activity
ribitol beta-1,4-xylosyltransferase activity (GO:0120053)
Namespace: molecular_function
Definition: Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.
positive regulation of gastric emptying (GO:0120062)
Namespace: biological_process
Definition: Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
rough endoplasmic reticulum cisterna (GO:0120083)
Namespace: cellular_component
Definition: A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity.
obsolete transposon integration involved in RNA-mediated transposition (GO:0120085)
Namespace: biological_process
Definition: OBSOLETE. Any transposon integration that contributes to a process of RNA-mediated transposition.
Synonyms: retrotransposon integration
Comment: This term was obsoleted because it represents a readout.
vacuole-isolation membrane contact site (GO:0120095)
Namespace: cellular_component
Definition: An organelle membrane contact site formed at the junction of the vacuolar membrane and the isolation membrane or phagophore in response to starvation or other stresses, leading to the formation of the autophagosome.
Synonyms: vacuole-IM contact site; vacuole-phagophore contact site; VICS
DNA-3'-diphospho-5'-guanosine diphosphatase activity (GO:0120108)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H+.
Synonyms: DNA-3'pp5'G guanylate hydrolase
cytoplasm to vacuole targeting by the NVT pathway (GO:0120113)
Namespace: biological_process
Definition: A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe.
Synonyms: protein localization by the Nbr1-mediated vacuolar targeting pathway
Lsm2-8 complex (GO:0120115)
Namespace: cellular_component
Definition: A heteroheptameric, nuclear protein complex composed of Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Lsm8, or orthologs thereof, that selectively binds to snRNAs, in particular U6 or U6atac snRNAs, and also to unspliced transcripts localized within the nucleus.
PNGase complex (GO:0120125)
Namespace: cellular_component
Definition: A protein complex responsible for the catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
obsolete regulation of mitotic actomyosin contractile ring disassembly (GO:0120150)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.
Comment: The reason for obsoletion is that the data from the paper for which the term was requested can be accurately described using another term
calcium-dependent outer dynein arm binding (GO:0120152)
Namespace: molecular_function
Definition: Binding to an outer dynein arm in the presence of calcium.
perithecium development (GO:0120165)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of a perithecium over time, from its formation to the mature structure. Peritheicum is a flask-shaped fruiting body of certain molds and ascomycetous fungi having a pore for the escape of spores. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.
obsolete positive regulation of actin filament bundle convergence involved in mitotic contractile ring assembly (GO:0120172)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.
Comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
obsolete regulation of actin filament bundle convergence involved in mitotic contractile ring assembly (GO:0120173)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of actin filament bundle convergence involved in mitotic contractile ring assembly.
Comment: The reason for obsoletion is that this term is pre-composed and should be represented as a GO-CAM model.
cell-substrate junction disassembly (GO:0120180)
Namespace: biological_process
Definition: The disaggregation of a cell-substrate junction into its constituent components.
positive regulation of focal adhesion disassembly (GO:0120183)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of disaggregation of a focal adhesion into its constituent components.
MBF transcription complex assembly (GO:0120185)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an MBF transcription complex.
Synonyms: DSC1 transcription factor complex assembly; MBF complex assembly; Mlu1-box binding factor assembly
positive regulation of protein localization to chromatin (GO:0120187)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.
Synonyms: positive regulation of protein localisation to chromatin
positive regulation of bile acid secretion (GO:0120189)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.
negative regulation of anther dehiscence (GO:0120196)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.
mucociliary clearance (GO:0120197)
Namespace: biological_process
Definition: The respiratory system process driven by motile cilia on epithelial cells of the respiratory tract by which mucus and associated inhaled particles and pathogens trapped within it are moved out of the airways.
Synonyms: MCC; MCT; mucociliary transport
rod telodendria (GO:0120210)
Namespace: cellular_component
Definition: Rod telodendria are projections that originate from the rod pedicle and form gap junctions with other photoreceptors within the outer plexiform layer of the retina.
sperm head-tail coupling apparatus (GO:0120212)
Namespace: cellular_component
Definition: A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.
Synonyms: head-tail coupling apparatus; HTCA; implantation fossa; sperm connecting piece; sperm neck
maintenance of ciliary planar beating movement pattern (GO:0120221)
Namespace: biological_process
Definition: Any process involved in maintaining the planar beating pattern of ciliary movement pattern. Connection between the outer doublets and the central pair via the radial spokes constrains ciliary movement to the planar beating pattern. Cilia that lack this connection, such as those in the embryonic node or Kupfer's vesicle, display radial movement.
Comment: Note that we deem cilium and microtubule-based flagellum to be equivalent.
outer dynein arm docking complex (GO:0120228)
Namespace: cellular_component
Definition: A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules.
Synonyms: ODA docking complex; ODA-DC
sperm glycocalyx (GO:0120238)
Namespace: cellular_component
Definition: The carbohydrate rich layer at the outermost periphery of a sperm cell.
obsolete terminal acetylenic compound catabolic process (GO:0120245)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of a terminal acetylenic compound, a compound which contains a terminal alkyne moiety in which a carbon of the carbon-carbon triple bond (aka C#C) moiety is attached to a hydrogen atom.
Synonyms: terminal alkyne substituted compound breakdown; terminal alkyne substituted compound catabolic process; terminal alkyne substituted compound catabolism; terminal alkyne substituted compound degradation
Comment: This term was obsoleted because it is an unnecessary grouping class.
olefinic compound metabolic process (GO:0120254)
Namespace: biological_process
Definition: The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C).
Synonyms: alkene substituted compound metabolic process; alkene substituted compound metabolism
regulation of cerebral blood circulation (GO:0120276)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cerebral blood circulation.
Synonyms: regulation of cerebrum blood circulation; regulation of telencephalon blood circulation
peptide lactyltransferase (CoA-dependent) activity (GO:0120300)
Namespace: molecular_function
Definition: Catalysis of the reaction: (L-lysyl-[protein] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[protein].
Synonyms: peptide lactyltransferase (CoA dependent) activity; peptide lactyltransferase activity; peptide lactyltransferase activity (CoA-dependent)
cellular response to actin cytoskeletal stress (GO:0120306)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of perturbations or damage to the actin cytoskeleton.
Synonyms: cellular response to actin cytoskeleton stress; cellular response to latrunculin A; cellular response to latrunculin B; response to latrunculin A; response to latrunculin B
ciliary basal body segregation (GO:0120312)
Namespace: biological_process
Definition: The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.
Synonyms: ciliary basal body separation; microtubule basal body segregation; microtubule basal body separation
regulation of oocyte karyosome formation (GO:0120313)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
olfactory sociosexual communication (GO:0120318)
Namespace: biological_process
Definition: The use of external chemical cues called pheromones to send social and sexual information between members of the same species, leading to specific behavioral responses. Pheromones may be detected by two olfactory sensory circuits, the main olfactory pathway and the vomeronasal system.
Comment: Behavior such as predation which involves members of different species is not social. Communication between members of different species is also not social behavior.