LiteFold/GO huggingface dataset:
alphaV-beta3 integrin-tissue transglutaminase complex (GO:0071089)
Namespace: cellular_component
Definition: A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.
Synonyms: ITGAV-ITGB3-TGM2 complex
response to interleukin-11 (GO:0071105)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.
Synonyms: response to IL-11
alpha9-beta1 integrin-osteopontin complex (GO:0071127)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.
Synonyms: ITGA9-ITGB1-SPP1 complex
alpha5-beta1 integrin-osteopontin complex (GO:0071128)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.
Synonyms: ITGA5-ITGB1-SPP1 complex
alpha9-beta1 integrin-ADAM8 complex (GO:0071133)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.
Synonyms: ITGA9-ITGB1-ADAM8 complex
alpha9-beta1 integrin-thrombospondin-1 complex (GO:0071134)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.
Synonyms: ITGA9-ITGB1-THBS1 complex
alpha7-beta1 integrin-focal adhesion kinase complex (GO:0071135)
Namespace: cellular_component
Definition: A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.
Synonyms: ITGA7-ITGB1-PTK2 complex
homomeric SMAD protein complex (GO:0071142)
Namespace: cellular_component
Definition: A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive.
Synonyms: SMAD1 homotrimer complex; SMAD1 protein complex; SMAD2 homotrimer complex; SMAD2 protein complex; SMAD3 homotrimer complex; SMAD3 protein complex
MAML3-RBP-Jkappa-ICN2 complex (GO:0071180)
Namespace: cellular_component
Definition: A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
Synonyms: MAML3-RBP-Jkappa-Notch2 complex
MAML3-RBP-Jkappa-ICN4 complex (GO:0071182)
Namespace: cellular_component
Definition: A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
Synonyms: MAML3-RBP-Jkappa-Notch4 complex
Kv4.3-DPP10 channel complex (GO:0071202)
Namespace: cellular_component
Definition: A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.
Synonyms: Kv4.3-DPPY channel complex
histone pre-mRNA DCP binding (GO:0071208)
Namespace: molecular_function
Definition: Binding to the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.
cellular response to tumor cell (GO:0071228)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
cellular response to chlorate (GO:0071246)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.
cellular response to nitrate (GO:0071249)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
cytoplasmic U snRNP body (GO:0071254)
Namespace: cellular_component
Definition: A focus in the cytoplasm that contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.
Synonyms: U body; U-body
translocon complex (GO:0071256)
Namespace: cellular_component
Definition: A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.
Synonyms: Sec complex-associated translocon complex
L-methionine biosynthetic process (GO:0071265)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.
Synonyms: L-methionine anabolism; L-methionine biosynthesis; L-methionine formation; L-methionine synthesis
cellular response to magnesium ion (GO:0071286)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
cellular response to rhamnose stimulus (GO:0071334)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.
Synonyms: cellular response to L-rhamnose stimulus
cellular response to interleukin-12 (GO:0071349)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
Synonyms: cellular response to IL-12
cellular response to exogenous dsRNA (GO:0071360)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
Synonyms: cellular response to exogenous double-stranded RNA; cellular response to viral dsRNA
cellular response to indolebutyric acid stimulus (GO:0071366)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.
Synonyms: cellular response to IBA stimulus; cellular response to indole-3-butyric acid stimulus
cellular response to gibberellin stimulus (GO:0071370)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
Synonyms: cellular response to gibberellic acid stimulus
cellular response to cortisol stimulus (GO:0071387)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
Synonyms: cellular response to hydrocortisone stimulus
cellular response to mineralocorticoid stimulus (GO:0071389)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
cellular response to ozone (GO:0071457)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
cellular response to pH (GO:0071467)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
cellular response to alkaline pH (GO:0071469)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
Synonyms: cellular response to alkalinity; cellular response to basic pH
cellular hypotonic response (GO:0071476)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
Synonyms: cellular hypo-osmotic response
cellular response to freezing (GO:0071497)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
Synonyms: antifreeze activity; ice nucleation inhibitor activity
obsolete MAPK import into nucleus involved in conjugation with cellular fusion (GO:0071512)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion.
Synonyms: conjugation with cellular fusion, MAPK import into nucleus; conjugation with cellular fusion, nuclear translocation of MAPK; MAPK import into nucleus involved in mating response; nuclear translocation of MAPK involved in conjugation with cellular fusion; nuclear translocation of MAPK involved in mating response
Comment: The reason for obsoletion is that this term represents a GO-CAM model.
obsolete RING-like zinc finger domain-mediated complex assembly (GO:0071536)
Namespace: biological_process
Definition: OBSOLETE. A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction.
Synonyms: RING-like domain-mediated complex assembly
Comment: This term was obsoleted because it represented a molecular function (binding), not a biological process. The term represented a domain involved in protein-protein interactions, but no necessarily the process of assembling a complex.
protein localization to centrosome (GO:0071539)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained at, the centrosome.
Synonyms: protein localisation to centrosome
cellular response to dexamethasone stimulus (GO:0071549)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
RIP homotypic interaction motif binding (GO:0071551)
Namespace: molecular_function
Definition: Binding to a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.
Synonyms: RHIM binding
cell wall organization or biogenesis (GO:0071554)
Namespace: biological_process
Definition: A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
Synonyms: cell wall organisation or biogenesis; cell wall organization or biogenesis at cellular level; cellular cell wall organisation or biogenesis; cellular cell wall organization or biogenesis
chemokine (C-C motif) ligand 5 production (GO:0071609)
Namespace: biological_process
Definition: The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL5 production; RANTES production; Regulated upon Activation, Normal T-cell Expressed, and Secreted production
chemokine (C-C motif) ligand 1 production (GO:0071610)
Namespace: biological_process
Definition: The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
Synonyms: CCL1 production; T cell activation 3 production; TCA-3 production
acyl-CoA biosynthetic process (GO:0071616)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
Synonyms: acyl-CoA anabolism; acyl-CoA biosynthesis; acyl-CoA formation; acyl-CoA synthesis
obsolete integral component of fungal-type vacuolar membrane (GO:0071627)
Namespace: cellular_component
Definition: OBSOLETE. The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
Synonyms: integral to fungal-type vacuolar membrane
Comment: This term was obsoleted because it represents protein topology, not a cellular component.
positive regulation of chemokine (C-C motif) ligand 5 production (GO:0071651)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
Synonyms: positive regulation of CCL5 production; positive regulation of RANTES production; positive regulation of Regulated upon Activation, Normal T-cell Expressed, and Secreted production
plant-type cell wall organization or biogenesis (GO:0071669)
Namespace: biological_process
Definition: A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.
Synonyms: plant-type cell wall organisation or biogenesis; plant-type cell wall organization and biogenesis
commissural neuron axon guidance (GO:0071679)
Namespace: biological_process
Definition: The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.
Synonyms: commissural neuron axon pathfinding
membrane macromolecule biosynthetic process (GO:0071710)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.
Synonyms: membrane macromolecule anabolism; membrane macromolecule biosynthesis; membrane macromolecule formation; membrane macromolecule synthesis
para-aminobenzoyl-glutamate hydrolase activity (GO:0071713)
Namespace: molecular_function
Definition: Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.
sodium-independent icosanoid transport (GO:0071718)
Namespace: biological_process
Definition: The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.
Synonyms: sodium-independent eicosanoid transport
sodium-independent thromboxane transport (GO:0071721)
Namespace: biological_process
Definition: The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
nuclear outer membrane organization (GO:0071764)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.
Synonyms: nuclear outer membrane organisation; nuclear outer membrane organization and biogenesis
endoplasmic reticulum cisternal network assembly (GO:0071784)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
Synonyms: endoplasmic reticulum cisternal network formation; ER cisternal network assembly; ER cisternal network formation
endoplasmic reticulum tubular network formation (GO:0071787)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
Synonyms: endoplasmic reticulum tubular network assembly; ER tubular network assembly; ER tubular network formation
positive regulation of podosome assembly (GO:0071803)
Namespace: biological_process
Definition: Any process that activates or increases the rate or extent of podosome assembly.
Synonyms: activation of podosome assembly; stimulation of podosome assembly; up regulation of podosome assembly; up-regulation of podosome assembly; upregulation of podosome assembly
BAT3 complex (GO:0071818)
Namespace: cellular_component
Definition: A protein complex found in mammals that transfers tail-anchored (TA) proteins from SGTA to GET3 (ASNA1/TRC4) for targeting to the endoplasmic reticulum membrane. Also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD). Consists of BAG6 (BAT3) and its cofactors GET4 (TRC35) and UBL4A.
Synonyms: Bag6 complex; BAG6-UBL4A-TRC35 complex; BAT3-TRC35-UBL4A complex
protein-lipid complex organization (GO:0071825)
Namespace: biological_process
Definition: Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.
Synonyms: protein-lipid complex subunit organisation; protein-lipid complex subunit organization
fungal-type cell wall organization or biogenesis (GO:0071852)
Namespace: biological_process
Definition: A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.
Synonyms: fungal-type cell wall organisation or biogenesis; fungal-type cell wall organization and biogenesis
neuropeptide receptor binding (GO:0071855)
Namespace: molecular_function
Definition: Binding to a neuropeptide receptor.
response to monoamine (GO:0071867)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
Synonyms: response to monoamine stimulus
response to epinephrine (GO:0071871)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.
Synonyms: response to adrenaline stimulus; response to epinephrine stimulus
Comment: Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors.
leukocyte apoptotic process (GO:0071887)
Namespace: biological_process
Definition: Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
Synonyms: leukocyte apoptosis
Comment: Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
odontoblast differentiation (GO:0071895)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.
prominosome (GO:0071914)
Namespace: cellular_component
Definition: An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.
Synonyms: prominin-containing extracellular membrane vesicle
urea transmembrane transport (GO:0071918)
Namespace: biological_process
Definition: The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
Synonyms: urea membrane transport
Comment: Note that this term is not intended for use in annotating lateral movement within membranes.
cleavage body (GO:0071920)
Namespace: cellular_component
Definition: A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
obsolete negative regulation of cohesin loading (GO:0071923)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
Synonyms: negative regulation of cohesin association with chromatin; negative regulation of cohesin localisation to chromatin; negative regulation of cohesin localization to chromatin
Comment: The reason for obsoletion is that this term represents the regulation of a molecular function.
tyramine signaling pathway (GO:0071928)
Namespace: biological_process
Definition: The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.
Synonyms: tyramine signalling pathway