LiteFold/GO huggingface dataset:
negative regulation of presynaptic active zone assembly (GO:1905519)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.
Synonyms: down regulation of pre-synaptic active zone assembly; down regulation of pre-synaptic active zone component assembly; down regulation of pre-synaptic active zone component formation; down regulation of pre-synaptic active zone formation; down regulation of presynaptic active zone assembly; down regulation of presynaptic active zone formation; down-regulation of pre-synaptic active zone assembly; down-regulation of pre-synaptic active zone component assembly; down-regulation of pre-synaptic active zone component formation; down-regulation of pre-synaptic active zone formation; down-regulation of presynaptic active zone assembly; down-regulation of presynaptic active zone formation; downregulation of pre-synaptic active zone assembly; downregulation of pre-synaptic active zone component assembly; downregulation of pre-synaptic active zone component formation; downregulation of pre-synaptic active zone formation; downregulation of presynaptic active zone assembly; downregulation of presynaptic active zone formation; inhibition of pre-synaptic active zone assembly; inhibition of pre-synaptic active zone component assembly; inhibition of pre-synaptic active zone component formation; inhibition of pre-synaptic active zone formation; inhibition of presynaptic active zone assembly; inhibition of presynaptic active zone formation; negative regulation of pre-synaptic active zone assembly; negative regulation of pre-synaptic active zone component assembly; negative regulation of pre-synaptic active zone component formation; negative regulation of pre-synaptic active zone formation; negative regulation of presynaptic active zone formation
regulation of eukaryotic translation initiation factor 4F complex assembly (GO:1905535)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
Synonyms: regulation of eIF-4F assembly; regulation of eIF4F assembly
ganglioside GM1 binding (GO:1905573)
Namespace: molecular_function
Definition: Binding to ganglioside GM1.
ganglioside GT1b binding (GO:1905576)
Namespace: molecular_function
Definition: Binding to ganglioside GT1b.
cellular response to acetaldehyde (GO:1905641)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.
obsolete negative regulation of DNA methylation (GO:1905642)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.
Synonyms: down regulation of DNA methylation; down-regulation of DNA methylation; downregulation of DNA methylation; inhibition of DNA methylation
Comment: This term was obsoleted because it represents regulation of a molecular function.
obsolete positive regulation of DNA methylation (GO:1905643)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of DNA methylation.
Synonyms: activation of DNA methylation; up regulation of DNA methylation; up-regulation of DNA methylation; upregulation of DNA methylation
Comment: This term was obsoleted because it represents regulation of a molecular function.
positive regulation of FACT complex assembly (GO:1905646)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of FACT complex assembly.
Synonyms: activation of Facilitates chromatin transcription complex assembly; activation of Facilitates chromatin transcription complex formation; activation of FACT complex assembly; activation of FACT complex formation; positive regulation of Facilitates chromatin transcription complex assembly; positive regulation of Facilitates chromatin transcription complex formation; positive regulation of FACT complex formation; up regulation of Facilitates chromatin transcription complex assembly; up regulation of Facilitates chromatin transcription complex formation; up regulation of FACT complex assembly; up regulation of FACT complex formation; up-regulation of Facilitates chromatin transcription complex assembly; up-regulation of Facilitates chromatin transcription complex formation; up-regulation of FACT complex assembly; up-regulation of FACT complex formation; upregulation of Facilitates chromatin transcription complex assembly; upregulation of Facilitates chromatin transcription complex formation; upregulation of FACT complex assembly; upregulation of FACT complex formation
negative regulation of lysosome organization (GO:1905672)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.
Synonyms: down regulation of lysosome organisation; down regulation of lysosome organization; down regulation of lysosome organization and biogenesis; down-regulation of lysosome organisation; down-regulation of lysosome organization; down-regulation of lysosome organization and biogenesis; downregulation of lysosome organisation; downregulation of lysosome organization; downregulation of lysosome organization and biogenesis; inhibition of lysosome organisation; inhibition of lysosome organization; inhibition of lysosome organization and biogenesis; negative regulation of lysosome organisation; negative regulation of lysosome organization and biogenesis
negative regulation of mitochondrial ATP synthesis coupled proton transport (GO:1905707)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.
regulation of mRNA cis splicing, via spliceosome (GO:1905744)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.
Synonyms: regulation of nuclear mRNA cis splicing, via spliceosome; regulation of nuclear mRNA cis splicing, via U2-type spliceosome; regulation of splicing
positive regulation of protection from non-homologous end joining at telomere (GO:1905766)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.
Synonyms: activation of protection from NHEJ-mediated telomere fusion; activation of protection from non-homologous end joining at telomere; positive regulation of protection from NHEJ-mediated telomere fusion; up regulation of protection from NHEJ-mediated telomere fusion; up regulation of protection from non-homologous end joining at telomere; up-regulation of protection from NHEJ-mediated telomere fusion; up-regulation of protection from non-homologous end joining at telomere; upregulation of protection from NHEJ-mediated telomere fusion; upregulation of protection from non-homologous end joining at telomere
obsolete regulation of double-stranded telomeric DNA binding (GO:1905767)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.
Comment: This term was obsoleted because it represents a molecular function.
8-hydroxy-2'-deoxyguanosine DNA binding (GO:1905773)
Namespace: molecular_function
Definition: Binding to 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.
positive regulation of phosphatidylserine exposure on apoptotic cell surface (GO:1905782)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
Synonyms: activation of externalization of phosphatidylserine; activation of phosphatidylserine exposure on apoptotic cell surface; positive regulation of externalization of phosphatidylserine; up regulation of externalization of phosphatidylserine; up regulation of phosphatidylserine exposure on apoptotic cell surface; up-regulation of externalization of phosphatidylserine; up-regulation of phosphatidylserine exposure on apoptotic cell surface; upregulation of externalization of phosphatidylserine; upregulation of phosphatidylserine exposure on apoptotic cell surface
negative regulation of intraciliary retrograde transport (GO:1905800)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.
Synonyms: down regulation of intraciliary retrograde transport; down regulation of intraflagellar retrograde transport; down-regulation of intraciliary retrograde transport; down-regulation of intraflagellar retrograde transport; downregulation of intraciliary retrograde transport; downregulation of intraflagellar retrograde transport; inhibition of intraciliary retrograde transport; inhibition of intraflagellar retrograde transport; negative regulation of intraflagellar retrograde transport
positive regulation of motor neuron axon guidance (GO:1905814)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.
Synonyms: activation of motoneuron axon guidance; activation of motor axon guidance; activation of motor axon pathfinding; activation of motor neuron axon guidance; positive regulation of motoneuron axon guidance; positive regulation of motor axon guidance; positive regulation of motor axon pathfinding; up regulation of motoneuron axon guidance; up regulation of motor axon guidance; up regulation of motor axon pathfinding; up regulation of motor neuron axon guidance; up-regulation of motoneuron axon guidance; up-regulation of motor axon guidance; up-regulation of motor axon pathfinding; up-regulation of motor neuron axon guidance; upregulation of motoneuron axon guidance; upregulation of motor axon guidance; upregulation of motor axon pathfinding; upregulation of motor neuron axon guidance
obsolete regulation of selenocysteine metabolic process (GO:1905825)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of selenocysteine metabolic process.
Synonyms: regulation of selenocysteine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete positive regulation of selenocysteine metabolic process (GO:1905827)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process.
Synonyms: activation of selenocysteine metabolic process; activation of selenocysteine metabolism; positive regulation of selenocysteine metabolism; up regulation of selenocysteine metabolic process; up regulation of selenocysteine metabolism; up-regulation of selenocysteine metabolic process; up-regulation of selenocysteine metabolism; upregulation of selenocysteine metabolic process; upregulation of selenocysteine metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
obsolete positive regulation of heparan sulfate binding (GO:1905855)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of heparan sulfate binding.
Synonyms: activation of heparan sulfate binding; up regulation of heparan sulfate binding; up-regulation of heparan sulfate binding; upregulation of heparan sulfate binding
Comment: This term was obsoleted because it represents a molecular function.
intranuclear rod assembly (GO:1905861)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of a set of components to form an intranuclear rod.
Synonyms: intranuclear actin rod assembly; intranuclear actin rod formation; intranuclear rod formation
negative regulation of oogenesis (GO:1905880)
Namespace: biological_process
Definition: Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis.
Synonyms: down regulation of oogenesis; down regulation of ovum development; down-regulation of oogenesis; down-regulation of ovum development; downregulation of oogenesis; downregulation of ovum development; inhibition of oogenesis; inhibition of ovum development; negative regulation of ovum development
regulation of cellular response to very-low-density lipoprotein particle stimulus (GO:1905890)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of cellular response to very-low-density lipoprotein particle stimulus.
Synonyms: regulation of cellular response to VLDL particle stimulus
regulation of mesoderm formation (GO:1905902)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of mesoderm formation.
obsolete positive regulation of invadopodium disassembly (GO:1905929)
Namespace: biological_process
Definition: OBSOLETE. Any process that activates or increases the frequency, rate or extent of invadopodium disassembly.
Synonyms: activation of invadopodium disassembly; up regulation of invadopodium disassembly; up-regulation of invadopodium disassembly; upregulation of invadopodium disassembly
Comment: This term was made obsolete because an invadopodium is an abnormal structure found in cancerous or transformed cells that is out of scope of GO.
regulation of formation of growth cone in injured axon (GO:1905942)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.
regulation of response to calcium ion (GO:1905945)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of response to calcium ion.
Synonyms: regulation of response to Ca2+ ion
methylglyoxal reductase (NADPH) (acetol producing) activity (GO:1990002)
Namespace: molecular_function
Definition: Catalysis of the reaction: hydroxyacetone + NADP+ = H+ + methylglyoxal + NADPH.
Synonyms: methylglyoxal reductase (NADPH-dependent, acetol producing)
complex laminated body (GO:1990012)
Namespace: cellular_component
Definition: A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.
Synonyms: CLB
presynaptic grid (GO:1990013)
Namespace: cellular_component
Definition: A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.
Synonyms: pre-synaptic grid
C bouton (GO:1990024)
Namespace: cellular_component
Definition: Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.
S bouton (GO:1990027)
Namespace: cellular_component
Definition: Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.
sclerotium development (GO:1990045)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.
DNA-5-methylcytosine glycosylase activity (GO:1990053)
Namespace: molecular_function
Definition: Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.
RPAP3/R2TP/prefoldin-like complex (GO:1990062)
Namespace: cellular_component
Definition: A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.
Synonyms: R2TP/prefoldin-like complex
rejection of pollen from other species (GO:1990109)
Namespace: biological_process
Definition: The recognition and rejection of pollen of one species by cells in the stigma of another species.
Synonyms: unilateral interspecific incompatibility
Gtr1-Gtr2 GTPase complex (GO:1990131)
Namespace: cellular_component
Definition: A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.
flavonoid sulfotransferase activity (GO:1990135)
Namespace: molecular_function
Definition: Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.
protein localization to cell tip (GO:1990151)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location at the cell tip.
Synonyms: protein localisation to cell tip
DnaB-DnaG complex (GO:1990156)
Namespace: cellular_component
Definition: A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.
Synonyms: DnaB-DnaG primosome complex
SCF complex disassembly in response to cadmium stress (GO:1990171)
Namespace: biological_process
Definition: The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.
EH domain binding (GO:1990175)
Namespace: molecular_function
Definition: Binding to an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.
cobalamin transport complex (GO:1990191)
Namespace: cellular_component
Definition: Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.
Synonyms: BtuCDF complex; cobalamin-transporting BtuCDF complex; vitamin B12 transport complex; vitamin B12-transporting BtuCDF complex
MdtBC Complex (GO:1990203)
Namespace: cellular_component
Definition: A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.
Synonyms: multidrug efflux pump MdtBC
oxidoreductase complex (GO:1990204)
Namespace: cellular_component
Definition: Any protein complex that possesses oxidoreductase activity.
Synonyms: oxidation-reduction complex; redox complex
jasmonyl-Ile conjugate hydrolase activity (GO:1990206)
Namespace: molecular_function
Definition: Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.
Synonyms: JA-Ile hydrolase
obsolete positive regulation by symbiont of jasmonic acid levels in host (GO:1990211)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because there is no evidence that this process exists.
obsolete positive regulation by symbiont of ethylene levels in host (GO:1990212)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Comment: This term was obsoleted because there is no evidence that this process exists.
symbiont-mediated activation of host transcription (GO:1990216)
Namespace: biological_process
Definition: A process in which a symbiont initiates, promotes, or enhances transcription of genes into mRNA in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: positive regulation by symbiont of host transcription
paranodal junction maintenance (GO:1990227)
Namespace: biological_process
Definition: The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
Synonyms: axoglial septate junction maintenance; paranodal axoglial junction maintenance; paranodal septate maintenance
proteasome core complex import into nucleus (GO:1990236)
Namespace: biological_process
Definition: The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.
obsolete regulation of transcription from RNA polymerase II promoter in response to DNA damage (GO:1990248)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.
Comment: This term was obsoleted because it represents a GO-CAM model.
transcription-coupled nucleotide-excision repair, DNA damage recognition complex (GO:1990250)
Namespace: cellular_component
Definition: A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
subsynaptic reticulum organization (GO:1990255)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
renal amino acid absorption (GO:1990297)
Namespace: biological_process
Definition: A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
laminin-423 trimer (GO:1990338)
Namespace: cellular_component
Definition: A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.
Synonyms: laminin-14 complex; laminin-423
heterochromatin domain (GO:1990343)
Namespace: cellular_component
Definition: A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).
Synonyms: HOOD
Comment: An example of this type of heterochromatin is found in Schizosaccharomyces pombe, where heterochromatin domains preferentially assemble at sexual differentiation genes and retrotransposons.
Kir2 inward rectifier potassium channel complex (GO:1990374)
Namespace: cellular_component
Definition: A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.
Synonyms: Kir2.1 complex
Comment: An example of this is Kcnj2 in mouse (P35561) in PMID:16834334 (inferred from direct assay).