LiteFold/GO huggingface dataset:
obsolete co-translational protein acetylation (GO:0034420)
Namespace: biological_process
Definition: OBSOLETE. The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.
Synonyms: co-translational protein amino acid acetylation; cotranslational protein amino acid acetylation
Comment: This term was obsoleted because it represents a molecular function.
etioplast membrane (GO:0034426)
Namespace: cellular_component
Definition: Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.
obsolete lipoprotein amino acid oxidation (GO:0034438)
Namespace: biological_process
Definition: OBSOLETE. The modification of a lipoprotein by oxidation of one or more amino acids in the protein.
Comment: This term was obsoleted because it represents a molecular function.
lipoprotein lipid oxidation (GO:0034439)
Namespace: biological_process
Definition: The modification of a lipoprotein by oxidation of the lipid group.
very-low-density lipoprotein particle clearance (GO:0034447)
Namespace: biological_process
Definition: The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
Synonyms: VLDL clearance
3'-5' RNA helicase activity (GO:0034458)
Namespace: molecular_function
Definition: Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.
Synonyms: 3' to 5' RNA helicase activity; ATP-dependent 3' to 5' RNA helicase activity; ATP-dependent 3'-5' RNA helicase activity
90S preribosome assembly (GO:0034463)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.
BBSome (GO:0034464)
Namespace: cellular_component
Definition: A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.
Synonyms: Bardet-Biedl syndrome complex
U1 snRNA 3'-end processing (GO:0034473)
Namespace: biological_process
Definition: Any process involved in forming the mature 3' end of a U1 snRNA molecule.
Synonyms: U1 snRNA 3' end processing
phosphatidylcholine phospholipase C activity (GO:0034480)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H+ + phosphocholine.
Synonyms: Clostridium oedematiens beta- and gamma-toxins activity; Clostridium welchii alpha-toxin activity; heat-labile hemolysin; lipophosphodiesterase I activity; phosphatidylcholine cholinephosphohydrolase activity; phosphatidylcholine phospholipase C-type activity; phospholipase C, acting on phosphatidylcholine
early endosome to Golgi transport (GO:0034498)
Namespace: biological_process
Definition: The directed movement of substances from early endosomes to the Golgi.
Synonyms: PGE to Golgi transport; post-Golgi endosome to Golgi transport
protein localization to chromosome (GO:0034502)
Namespace: biological_process
Definition: Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
Synonyms: condensin localization to chromosome; protein localisation to chromosome
U3 snoRNA binding (GO:0034511)
Namespace: molecular_function
Definition: Binding to a U3 small nucleolar RNA.
obsolete 1-naphthaldehyde dehydrogenase activity (GO:0034525)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity (GO:0034529)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 1-methylnaphthalene hydroxylase activity (GO:0034534)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete 2-hydroxy-8-methylchromene-2-carboxylate isomerase activity (GO:0034536)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete isoproturon dimethylaminedehydrogenase activity (GO:0034568)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity (GO:0034571)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 4-isopropylaniline dehydrogenase activity (GO:0034575)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
piRNA binding (GO:0034584)
Namespace: molecular_function
Definition: Binding to a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
Synonyms: Piwi-associated RNA binding
response to hermaphrodite contact (GO:0034606)
Namespace: biological_process
Definition: The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.
organelle-enclosing lipid monolayer (GO:0034646)
Namespace: cellular_component
Definition: A lipid monolayer that surrounds and encloses an organelle.
obsolete histone demethylase activity (H3-dimethyl-K4 specific) (GO:0034648)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.
Synonyms: histone demethylase activity (H3-K4-me2 specific)
Comment: This term was obsoleted to align with RHEA and EC: this is a sub-reaction both in RHEA:60208 and EC:1.14.11.67.
obsolete ncRNA catabolic process (GO:0034661)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
endoplasmic reticulum chaperone complex (GO:0034663)
Namespace: cellular_component
Definition: A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.
Synonyms: endoplasmic reticulum network complex; ER chaperone complex; ER network complex
integrin alpha4-beta7 complex (GO:0034669)
Namespace: cellular_component
Definition: An integrin complex that comprises one alpha4 subunit and one beta7 subunit.
Synonyms: alpha4-beta7 integrin complex; ITGA4-ITGB7 complex
integrin alpha6-beta1 complex (GO:0034675)
Namespace: cellular_component
Definition: An integrin complex that comprises one alpha6 subunit and one beta1 subunit.
Synonyms: alpha6-beta1 integrin complex; ITGA6-ITGB1 complex; VLA-6 complex
type I transforming growth factor beta receptor binding (GO:0034713)
Namespace: molecular_function
Definition: Binding to a type I transforming growth factor beta receptor.
Synonyms: babo binding; babo ligand; baboon binding; baboon ligand; baboon receptor ligand; sax binding; sax ligand; saxophone binding; saxophone ligand; TGF-beta type I binding; thickveins binding; thickveins ligand; tkv binding; tkv ligand; transforming growth factor beta ligand binding to type I receptor; transforming growth factor beta receptor type I binding; type I TGF-beta binding
Gemin6-Gemin7-unrip complex (GO:0034717)
Namespace: cellular_component
Definition: A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.
nucleosome organization (GO:0034728)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.
Synonyms: nucleosome organisation
obsolete histone H3-K79 methylation (GO:0034729)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.
Synonyms: histone H3 K79 methylation; histone H3K79me; histone lysine H3 K79 methylation
Comment: This term was obsoleted because it represents a molecular function.
transcription factor TFIIIB-alpha complex (GO:0034732)
Namespace: cellular_component
Definition: A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.
Scrib-APC complex (GO:0034749)
Namespace: cellular_component
Definition: A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.
Synonyms: hScrib-APC complex
Comment: Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.
cytosolic aryl hydrocarbon receptor complex (GO:0034752)
Namespace: cellular_component
Definition: An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.
Synonyms: 9S-cytosolic aryl hydrocarbon (Ah) receptor non-ligand activated complex; cytosolic AhR complex; cytosolic AHRC
negative regulation of iron ion transmembrane transport (GO:0034760)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
Synonyms: down regulation of transmembrane iron ion transport; down-regulation of transmembrane iron ion transport; downregulation of transmembrane iron ion transport; inhibition of transmembrane iron ion transport; negative regulation of iron ion membrane transport; negative regulation of transmembrane iron ion transport; negative regulation of transmembrane iron transport
obsolete glyphosate dehydrogenase activity (GO:0034780)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete dimethylmalonate decarboxylase activity (GO:0034782)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete fosfomycin 2-glutathione ligase activity (GO:0034797)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete anthracene 9,10-dioxygenase activity (GO:0034816)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 3-HSA hydroxylase activity (GO:0034819)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete citronellal dehydrogenase activity (GO:0034822)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete mentha-1,3-dione-CoA ligase activity (GO:0034841)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete isooctane monooxygenase activity (GO:0034850)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete 2,4,4-trimethylpent-2-enoyl-CoA hydratase activity (GO:0034867)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity (GO:0034868)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete citrazinate dehydrogenase activity (GO:0034880)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete endosulfan lactone lactonase activity (GO:0034892)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 5-chloro-2-oxopent-4-enoate hydratase activity (GO:0034904)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete 5-chloro-4-hydroxy-2-oxopentanate aldolase activity (GO:0034905)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete terephthalate decarboxylase activity (GO:0034947)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
obsolete diphenyl ether 2,3-dioxygenase activity (GO:0034954)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.
Comment: This term was obsoleted because there is no evidence that this specific activity exists.
obsolete 3-nitrophenol nitroreductase activity (GO:0034957)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O.
Comment: This term was obsoleted because there is no evidence that this specific reaction exists.
endothelin maturation (GO:0034959)
Namespace: biological_process
Definition: The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.
response to endoplasmic reticulum stress (GO:0034976)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
Synonyms: cellular response to endoplasmic reticulum stress; ER stress response; response to ER stress
Ecsit-NDUFAF1 complex (GO:0034985)
Namespace: cellular_component
Definition: Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.
obsolete oligosaccharyltransferase III complex (GO:0035000)
Namespace: cellular_component
Definition: OBSOLETE. An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.
Synonyms: OSTCIII
Comment: The reason for obsoletion is that the meaning of the term is ambiguous and the data from the paper for which the term was requested can be accurately described using GO:0008250 oligosaccharyltransferase complex.
somatic stem cell population maintenance (GO:0035019)
Namespace: biological_process
Definition: Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
negative regulation of Rac protein signal transduction (GO:0035021)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.
Synonyms: down regulation of Rac protein signal transduction; down-regulation of Rac protein signal transduction; downregulation of Rac protein signal transduction; inhibition of Rac protein signal transduction
negative regulation of Rho protein signal transduction (GO:0035024)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
Synonyms: down regulation of Rho protein signal transduction; down-regulation of Rho protein signal transduction; downregulation of Rho protein signal transduction; inhibition of Rho protein signal transduction
cardiocyte differentiation (GO:0035051)
Namespace: biological_process
Definition: The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
Synonyms: cardiac cell differentiation; heart cell differentiation
obsolete ecdysone-mediated induction of salivary gland cell autophagic cell death (GO:0035072)
Namespace: biological_process
Definition: OBSOLETE. Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.
Comment: The reason for obsoletion is that this term was added in error.
induction of programmed cell death by ecdysone (GO:0035078)
Namespace: biological_process
Definition: Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.
establishment of apical/basal cell polarity (GO:0035089)
Namespace: biological_process
Definition: The specification and formation of the polarity of a cell along its apical/basal axis.
ESC/E(Z) complex (GO:0035098)
Namespace: cellular_component
Definition: A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Synonyms: Extra Sex Combs/Enhancer of Zeste complex; polycomb repressive complex 2; PRC2 complex
PRC1 complex (GO:0035102)
Namespace: cellular_component
Definition: A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
Synonyms: Polycomb repressive complex 1
Comment: In Drosophila the core subunits are Pc (Polycomb), Psc (Posterior sex combs), Ph (Polyhomeotic) and Sce (Sex comb extra). In mammals, which have several orthologs for each of the Drosophila core proteins, a family of distinct PRC1-like complexes seem to exist which contain at least some PcG proteins in mutually exclusive manner.
obsolete leg joint morphogenesis (GO:0035111)
Namespace: biological_process
Definition: OBSOLETE. The process in which the anatomical structures of a leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. One example is the knee, which separates the leg tibia and femur.
Synonyms: leg joint morphogenesis
Comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.
post-embryonic hindlimb morphogenesis (GO:0035129)
Namespace: biological_process
Definition: The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.
maintenance of epithelial integrity, open tracheal system (GO:0035160)
Namespace: biological_process
Definition: Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.
Synonyms: maintenance of tracheal epithelial integrity
embryonic crystal cell differentiation (GO:0035165)
Namespace: biological_process
Definition: The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.