LiteFold/GO huggingface dataset:
trypanothione catabolic process (GO:0046207)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
Synonyms: trypanothione breakdown; trypanothione catabolism; trypanothione degradation
nitric oxide metabolic process (GO:0046209)
Namespace: biological_process
Definition: The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
Synonyms: nitric oxide metabolism
aflatoxin metabolic process (GO:0046222)
Namespace: biological_process
Definition: The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
Synonyms: aflatoxin B metabolic process; aflatoxin B1 metabolic process; aflatoxin B1 metabolism; aflatoxin B2 metabolic process; aflatoxin B2 metabolism; aflatoxin metabolism
obsolete 2-aminobenzenesulfonate biosynthetic process (GO:0046229)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
Synonyms: 2-aminobenzenesulfonate anabolism; 2-aminobenzenesulfonate biosynthesis; 2-aminobenzenesulfonate biosynthetic process; 2-aminobenzenesulfonate formation; 2-aminobenzenesulfonate synthesis; 2-aminobenzenesulphonate biosynthesis; 2-aminobenzenesulphonate biosynthetic process
Comment: This term was made obsolete because 2-aminobenzenesulfonate is not synthesized by living organisms, and GO does not cover non-biological processes.
obsolete 3-hydroxyphenylacetate biosynthetic process (GO:0046233)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
Synonyms: 3-hydroxyphenylacetate anabolism; 3-hydroxyphenylacetate biosynthesis; 3-hydroxyphenylacetate biosynthetic process; 3-hydroxyphenylacetate formation; 3-hydroxyphenylacetate synthesis
Comment: This term was made obsolete because 3-hydroxyphenylacetate is not synthesized by living organisms and GO does not cover non-biological processes.
obsolete p-xylene biosynthetic process (GO:0046243)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.
Synonyms: p-xylene anabolism; p-xylene biosynthesis; p-xylene biosynthetic process; p-xylene formation; p-xylene synthesis; para-xylene biosynthesis; para-xylene biosynthetic process
Comment: This term was made obsolete because p-xylene is not synthesized by living organisms, and GO does not cover non-biological processes.
stilbene catabolic process (GO:0046272)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.
Synonyms: stilbene breakdown; stilbene catabolism; stilbene degradation
lignan catabolic process (GO:0046273)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
Synonyms: lignan breakdown; lignan catabolism; lignan degradation
formaldehyde biosynthetic process (GO:0046293)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.
Synonyms: formaldehyde anabolism; formaldehyde biosynthesis; formaldehyde formation; formaldehyde synthesis; methanal biosynthesis; methanal biosynthetic process
obsolete 2,4-dichlorophenoxyacetic acid biosynthetic process (GO:0046299)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
Synonyms: 2,4-dichlorophenoxyacetic acid anabolism; 2,4-dichlorophenoxyacetic acid biosynthesis; 2,4-dichlorophenoxyacetic acid biosynthetic process; 2,4-dichlorophenoxyacetic acid formation; 2,4-dichlorophenoxyacetic acid synthesis
Comment: This term was made obsolete because 2,4-dichlorophenoxyacetic acid is not synthesized by living organisms and GO does not cover non-biological processes.
2,4-dichlorophenoxyacetic acid catabolic process (GO:0046300)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
Synonyms: 2,4-dichlorophenoxyacetic acid breakdown; 2,4-dichlorophenoxyacetic acid catabolism; 2,4-dichlorophenoxyacetic acid degradation
obsolete 1,3-dichloro-2-propanol biosynthetic process (GO:0046309)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.
Synonyms: 1,3-dichloro-2-propanol anabolism; 1,3-dichloro-2-propanol biosynthesis; 1,3-dichloro-2-propanol formation; 1,3-dichloro-2-propanol synthesis
Comment: 1,3-dichloro-2-propanol is not a natural compound.
obsolete phosphoarginine biosynthetic process (GO:0046312)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine.
Synonyms: phosphoarginine anabolism; phosphoarginine biosynthesis; phosphoarginine formation; phosphoarginine synthesis
Comment: The reason for obsoletion is that this represents a molecular function.
positive regulation of D-glucose import across plasma membrane (GO:0046326)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell.
Synonyms: activation of glucose import; positive regulation of glucose import; positive regulation of glucose uptake; stimulation of glucose import; up regulation of glucose import; up-regulation of glucose import; upregulation of glucose import
regulation of JNK cascade (GO:0046328)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
Synonyms: regulation of SAPK cascade
positive regulation of JNK cascade (GO:0046330)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
Synonyms: activation of JNK cascade; stimulation of JNK cascade; up regulation of JNK cascade; up-regulation of JNK cascade; upregulation of JNK cascade
aminoglycoside 3-N-acetyltransferase activity (GO:0046353)
Namespace: molecular_function
Definition: Catalysis of the reaction: a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3)-acetyl-2-deoxystreptamine antibiotic + CoA + H+.
Synonyms: 3-aminoglycoside acetyltransferase activity; 3-N-aminoglycoside acetyltransferase activity; acetyl-CoA:2-deoxystreptamine-antibiotic N3-acetyltransferase activity; acetyl-CoA:gentamicin-C N3-acetyltransferase activity; aminoglycoside acetyltransferase AAC(3)-1; aminoglycoside acetyltransferase AAC(3)-I activity; gentamicin 3-N-acetyltransferase activity; gentamicin acetyltransferase I activity; gentamicin-(3)-N-acetyltransferase activity; gentamycin 3-N-acetyltransferase activity; gentamycin acetyltransferase I
monosaccharide catabolic process (GO:0046365)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms: monosaccharide breakdown; monosaccharide catabolism; monosaccharide degradation
UDP-glucuronate metabolic process (GO:0046398)
Namespace: biological_process
Definition: The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
Synonyms: UDP-glucuronate metabolism
positive regulation of receptor signaling pathway via JAK-STAT (GO:0046427)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
Synonyms: activation of JAK-STAT cascade; positive regulation of STAT protein import into nucleus; positive regulation of STAT protein nuclear translocation; stimulation of JAK-STAT cascade; up regulation of JAK-STAT cascade; up-regulation of JAK-STAT cascade; upregulation of JAK-STAT cascade
obsolete 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process (GO:0046432)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
Synonyms: 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
FAD metabolic process (GO:0046443)
Namespace: biological_process
Definition: The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.
Synonyms: FAD metabolism; oxidized flavin adenine dinucleotide metabolic process; oxidized flavin adenine dinucleotide metabolism; oxidized flavin-adenine dinucleotide metabolic process; oxidized flavin-adenine dinucleotide metabolism
prostanoid biosynthetic process (GO:0046457)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.
Synonyms: prostanoid anabolism; prostanoid biosynthesis; prostanoid formation; prostanoid synthesis
hexadecanal metabolic process (GO:0046458)
Namespace: biological_process
Definition: The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
Synonyms: hexadecanal metabolism
glycerophospholipid catabolic process (GO:0046475)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
Synonyms: glycerophospholipid breakdown; glycerophospholipid catabolism; glycerophospholipid degradation; phosphoglyceride catabolic process; phosphoglyceride catabolism
uroporphyrinogen III metabolic process (GO:0046502)
Namespace: biological_process
Definition: The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.
Synonyms: uroporphyrinogen III metabolism
obsolete alpha-factor export (GO:0046542)
Namespace: biological_process
Definition: OBSOLETE. The directed movement of alpha-factor, one of the two yeast mating factors, out of a cell.
Synonyms: alpha-factor export
Comment: This term was made obsolete because it is a gene product based term and it does not involve a unique process.
development of primary male sexual characteristics (GO:0046546)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.
D-malate dehydrogenase (decarboxylating) (NAD+) activity (GO:0046553)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.
Synonyms: (R)-malate:NAD+ oxidoreductase (decarboxylating); bifunctional L(+)-tartrate dehydrogenase-D(+)-malate (decarboxylating); D-malate dehydrogenase activity; D-malic enzyme
glucuronidase activity (GO:0046574)
Namespace: molecular_function
Definition: Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.
Synonyms: glucuronyl hydrolase activity; glycuronidase activity
intercellular canaliculus (GO:0046581)
Namespace: cellular_component
Definition: An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.
enniatin biosynthetic process (GO:0046585)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.
Synonyms: enniatin anabolism; enniatin biosynthesis; enniatin formation; enniatin synthesis
regulation of calcium-dependent cell-cell adhesion (GO:0046586)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
negative regulation of calcium-dependent cell-cell adhesion (GO:0046588)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.
Synonyms: down regulation of calcium-dependent cell-cell adhesion; down-regulation of calcium-dependent cell-cell adhesion; downregulation of calcium-dependent cell-cell adhesion; inhibition of calcium-dependent cell-cell adhesion
obsolete embryonic leg morphogenesis (GO:0046590)
Namespace: biological_process
Definition: OBSOLETE. The process, occurring in the embryo, by which the anatomical structures of the leg are generated and organized. A leg is a limb on which an animal walks and stands.
Synonyms: embryonic leg morphogenesis
Comment: This term was made obsolete because leg is a mechano-functional grouping, and having both 'leg morphogenesis' and 'hindlimb morphogenesis' terms causes errors in querying.
carotenoid isomerase activity (GO:0046608)
Namespace: molecular_function
Definition: Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.
obsolete voltage-gated sulfate antiporter activity (GO:0046609)
Namespace: molecular_function
Definition: OBSOLETE. Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential.
Synonyms: prestin; voltage gated sulfate antiporter activity; voltage-dependent sulfate antiporter activity; voltage-sensitive sulfate antiporter activity; voltage-sensitive sulphate antiporter activity
Comment: This term was obsoleted because there is no evidence that this function exists.
sphingolipid binding (GO:0046625)
Namespace: molecular_function
Definition: Binding to a sphingolipid, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
alpha-beta T cell activation (GO:0046631)
Namespace: biological_process
Definition: The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms: alpha-beta T lymphocyte activation; alpha-beta T-cell activation; alpha-beta T-lymphocyte activation
negative regulation of gamma-delta T cell proliferation (GO:0046647)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.
Synonyms: down regulation of gamma-delta T cell proliferation; down-regulation of gamma-delta T cell proliferation; downregulation of gamma-delta T cell proliferation; inhibition of gamma-delta T cell proliferation; negative regulation of gamma-delta T lymphocyte proliferation; negative regulation of gamma-delta T-cell proliferation; negative regulation of gamma-delta T-lymphocyte proliferation
positive regulation of gamma-delta T cell proliferation (GO:0046648)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.
Synonyms: activation of gamma-delta T cell proliferation; positive regulation of gamma-delta T lymphocyte proliferation; positive regulation of gamma-delta T-cell proliferation; positive regulation of gamma-delta T-lymphocyte proliferation; stimulation of gamma-delta T cell proliferation; up regulation of gamma-delta T cell proliferation; up-regulation of gamma-delta T cell proliferation; upregulation of gamma-delta T cell proliferation
negative regulation of retinal cell programmed cell death (GO:0046671)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.
Synonyms: down regulation of retinal programmed cell death; down-regulation of retinal programmed cell death; downregulation of retinal programmed cell death; inhibition of retinal programmed cell death; negative regulation of retinal programmed cell death
IDP metabolic process (GO:0046707)
Namespace: biological_process
Definition: The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.
Synonyms: IDP metabolism
borate transport (GO:0046713)
Namespace: biological_process
Definition: The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
Synonyms: boron transport
active borate transmembrane transporter activity (GO:0046715)
Namespace: molecular_function
Definition: Enables the transport of borate across a membrane against the concentration gradient.
Synonyms: borate transmembrane transporter activity; borate uptake transmembrane transporter activity; boron transmembrane transporter activity; boron uptake transmembrane transporter activity; efflux-type borate transporter; efflux-type boron transporter
oxalic acid secretion (GO:0046724)
Namespace: biological_process
Definition: The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.
Synonyms: oxalate secretion
negative regulation by virus of viral protein levels in host cell (GO:0046725)
Namespace: biological_process
Definition: Any process where the infecting virus reduces the levels of viral proteins in a cell.
Synonyms: down regulation of viral protein levels in host cell; down-regulation of viral protein levels in host cell; downregulation of viral protein levels in host cell; inhibition of viral protein levels in host cell; negative regulation of viral protein levels
protein autophosphorylation (GO:0046777)
Namespace: biological_process
Definition: The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
Synonyms: protein amino acid autophosphorylation
host cell surface receptor binding (GO:0046789)
Namespace: molecular_function
Definition: Binding to a receptor on the host cell surface.
Synonyms: cell surface antigen activity, host-interacting; cell surface receptor ligand
exit of virus from host cell nucleus by nuclear egress (GO:0046802)
Namespace: biological_process
Definition: The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.
Synonyms: capsid egress; egress of viral procapsid from host cell nucleus; nuclear egress; nuclear egress of viral procapsid
virion transport vesicle (GO:0046816)
Namespace: cellular_component
Definition: A vesicle used to transport the partial or complete virion between cellular compartments.
regulation of RNA export from nucleus (GO:0046831)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.
Synonyms: regulation of RNA export from cell nucleus; regulation of RNA export out of nucleus; regulation of RNA transport from nucleus to cytoplasm; regulation of RNA-nucleus export
negative regulation of RNA export from nucleus (GO:0046832)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.
Synonyms: down regulation of RNA export from nucleus; down-regulation of RNA export from nucleus; downregulation of RNA export from nucleus; inhibition of RNA export from nucleus; negative regulation of RNA export from cell nucleus; negative regulation of RNA export out of nucleus; negative regulation of RNA transport from nucleus to cytoplasm; negative regulation of RNA-nucleus export
obsolete inositol or phosphatidylinositol phosphorylation (GO:0046853)
Namespace: biological_process
Definition: OBSOLETE. The process of introducing a phosphate group into inositol or a phosphatidylinositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.
Synonyms: inositol and derivative phosphorylation; inositol or phosphatidylinositol phosphorylation; myo-inositol and derivative phosphorylation; myo-inositol or phosphatidyl-myo-inositol phosphorylation
Comment: This term was made obsolete because it is a grouping term representing two quite different sets of entities, hexose sugars and glycerophospholipids.
metal ion binding (GO:0046872)
Namespace: molecular_function
Definition: Binding to a metal ion.
Synonyms: heavy metal binding; metal binding
regulation of follicle-stimulating hormone secretion (GO:0046880)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
Synonyms: regulation of follicle stimulating hormone secretion; regulation of FSH secretion
regulation of hormone secretion (GO:0046883)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.
follicle-stimulating hormone secretion (GO:0046884)
Namespace: biological_process
Definition: The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
Synonyms: follicle stimulating hormone secretion; follitropin secretion; FSH secretion
regulation of hormone biosynthetic process (GO:0046885)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
Synonyms: regulation of hormone anabolism; regulation of hormone biosynthesis; regulation of hormone formation; regulation of hormone synthesis
pyruvyltransferase activity (GO:0046919)
Namespace: molecular_function
Definition: Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.
pore complex (GO:0046930)
Namespace: cellular_component
Definition: A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids.
Synonyms: channel-forming toxin activity; pore; pore-forming toxin activity