LiteFold/GO huggingface dataset:
response to peptide hormone (GO:0043434)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
Synonyms: response to peptide hormone stimulus; response to polypeptide hormone stimulus
obsolete acetone biosynthetic process (GO:0043445)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of acetone, propan-2-one.
Synonyms: 2-propanone biosynthesis; 2-propanone biosynthetic process; acetone anabolism; acetone biosynthesis; acetone formation; acetone synthesis; dimethyl ketone biosynthesis; dimethyl ketone biosynthetic process; propan-2-one biosynthesis; propan-2-one biosynthetic process
Comment: This term was obsoleted because it is not a biological process as defined by GO.
regulation of rhamnose catabolic process (GO:0043463)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
Synonyms: regulation of rhamnose breakdown; regulation of rhamnose catabolism; regulation of rhamnose degradation
obsolete anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light (GO:0043483)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.
Synonyms: anthocyanin biosynthesis during anthocyanin accumulation in tissues in response to UV light stimulus; anthocyanin biosynthetic process during anthocyanin accumulation in response to UV light; anthocyanin biosynthetic process during anthocyanin accumulation in tissues in response to UV light stimulus
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM.
obsolete histone exchange (GO:0043486)
Namespace: biological_process
Definition: OBSOLETE. The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.
Synonyms: histone chaperone; histone replacement
Comment: This term was obsoleted because it represents a molecular function, histone chaperone activity.
obsolete regulation of protein homodimerization activity (GO:0043496)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
Comment: This term was obsoleted because it represents a molecular function. Consider molecular function regulator activity ; GO:0098772 or a child.
GET complex (GO:0043529)
Namespace: cellular_component
Definition: An endoplasmic reticulum protein-containing complex that is conserved in eukaryotics and that mediates the insertion of tail-anchored proteins into the ER membrane. In yeast, includes Get1p, Get2p and Get3p proteins.
cellular response to nitrogen levels (GO:0043562)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.
sporangium development (GO:0043582)
Namespace: biological_process
Definition: The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.
Synonyms: sporangia development
exosporium (GO:0043592)
Namespace: cellular_component
Definition: The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.
Synonyms: epispore; exospore; perispore
outer endospore membrane (GO:0043594)
Namespace: cellular_component
Definition: The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.
obsolete amide metabolic process (GO:0043603)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC.
isoprene biosynthetic process (GO:0043612)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of isoprene, C5H8.
Synonyms: 2-methyl-1,3-butadiene biosynthesis; 2-methyl-1,3-butadiene biosynthetic process; hemiterpene biosynthesis; hemiterpene biosynthetic process
obsolete regulation of transcription from RNA polymerase II promoter in response to stress (GO:0043618)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Comment: This term was obsoleted because it represents a GO-CAM model.
dicarboxylic acid catabolic process (GO:0043649)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms: dicarboxylate catabolic process; dicarboxylate catabolism; dicarboxylic acid breakdown; dicarboxylic acid catabolism; dicarboxylic acid degradation
recognition of apoptotic cell (GO:0043654)
Namespace: biological_process
Definition: The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.
Synonyms: detection of apoptotic cell; detection of apoptotic cell corpse; detection of cell corpse; recognition of apoptotic cell corpse; recognition of cell corpse
obsolete regulation of phosphoprotein phosphatase activity (GO:0043666)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.
Synonyms: regulation of calcineurin activity; regulation of protein phosphatase 3 activity; regulation of protein phosphatase type 2 activity; regulation of protein phosphatase type 2A activity; regulation of protein phosphatase type 2B activity
Comment: The reason for obsoletion is that this term represents a single-step process (regulation of MF).
pollen wall (GO:0043667)
Namespace: cellular_component
Definition: The wall surrounding a mature pollen grain; a multilayered structure consisting of a pectocellulosic intine surrounded by a sporopollenin-based exine, which itself contains two layers, the inner nexine and the outer sexine.
Synonyms: microspore wall
carotenoid vesicle (GO:0043702)
Namespace: cellular_component
Definition: A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.
cell adhesion involved in single-species biofilm formation in or on host organism (GO:0043707)
Namespace: biological_process
Definition: The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.
Synonyms: cell adhesion during single-species biofilm formation in or on host organism
cell adhesion involved in multi-species biofilm formation (GO:0043710)
Namespace: biological_process
Definition: The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.
Synonyms: cell adhesion during multi-species biofilm formation
2-hydroxyisocaproate CoA-transferase activity (GO:0043712)
Namespace: molecular_function
Definition: Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.
Synonyms: (R)-2-hydroxyisocaproate CoA transferase activity; (R)-2-hydroxyisocaproate CoA-transferase activity
2-hydroxymethylglutarate dehydrogenase activity (GO:0043718)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD+ = 2-formylglutarate + H+ + NADH.
Synonyms: (S)-2-hydroxymethylglutarate:NAD+ oxidoreductase activity; HgD
adenosylcobinamide hydrolase activity (GO:0043756)
Namespace: molecular_function
Definition: Catalysis of the reaction: adenosylcobinamide + H2O = (R)-1-aminopropan-2-ol + adenosylcobyrate.
Synonyms: adenosylcobinamide amidohydrolase activity; AdoCbi amidohydrolase activity; AdoCbi hydrolase activity; CbiZ
UTP:glucose-1-phosphate uridylyltransferase regulator activity (GO:0043763)
Namespace: molecular_function
Definition: Binds to and modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.
Synonyms: glucose-1-phosphate uridylyltransferase regulator activity; UDP-glucose diphosphorylase regulator activity; UDP-glucose pyrophosphorylase regulator activity
coenzyme F420-0 gamma-glutamyl ligase activity (GO:0043773)
Namespace: molecular_function
Definition: Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.
Synonyms: F420-0 gamma-glutamyl ligase activity
cobalt-precorrin-8 methylmutase activity (GO:0043778)
Namespace: molecular_function
Definition: Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.
Synonyms: cobalt-precorrin 8 methylmutase activity; cobalt-precorrin 8X methylmutase activity; cobalt-precorrin-8X methylmutase activity
6-phospho-3-hexuloisomerase activity (GO:0043800)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-arabino-hex-3-ulose 6-phosphate = beta-D-fructose 6-phosphate.
Synonyms: hexulose-6-phosphate isomerase activity; HUMPI
phospholactate guanylyltransferase activity (GO:0043814)
Namespace: molecular_function
Definition: Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.
spheroidene monooxygenase activity (GO:0043823)
Namespace: molecular_function
Definition: Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.
thiosulfate dehydrogenase (quinone) activity (GO:0043831)
Namespace: molecular_function
Definition: Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.
Synonyms: DoxA; DoxD; thiosulfate oxidoreductase, tetrathionate-forming activity; thiosulfate:6-decylubiquinone oxidoreductase activity; thiosulfate:quinone oxidoreductase activity; thiosulphate dehydrogenase (quinone) activity; thiosulphate:quinone oxidoreductase activity; TQO
L-valine dehydrogenase (NAD+) activity (GO:0043837)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-valine + NAD+ + H2O = 3-methyl-2-oxobutanoate + NH4+ + NADH + H+.
Synonyms: ValDH; valine dehydrogenase (NAD) activity; valine dehydrogenase (NAD+) activity
obsolete cyanophycinase activity (GO:0043859)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.
Synonyms: cyanophycinase activity
Comment: This term was made obsolete because it represents a gene product.
arginine:agmatine antiporter activity (GO:0043862)
Namespace: molecular_function
Definition: Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).
Synonyms: AdiC; arginine-agmatine antiporter activity; arginine-agmatine exchange transporter activity; arginine/agmatine antiporter activity
4-hydroxy-2-ketopimelate aldolase activity (GO:0043863)
Namespace: molecular_function
Definition: Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.
Synonyms: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase activity; HHED aldolase activity; HpaI; HpcH
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity (GO:0043878)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.
Synonyms: glyceraldehyde-3-phosphate dehydrogenase (NAD) (non-phosphorylating) activity; glyceraldehyde-3-phosphate dehydrogenase (NAD) activity; NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase activity; non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (NAD)
glycolate transmembrane transporter activity (GO:0043879)
Namespace: molecular_function
Definition: Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).
Synonyms: glcA; glycolate permease; glycolic acid transmembrane transporter activity; hydroxyacetic acid transmembrane transporter activity
malate:sodium symporter activity (GO:0043882)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).
Synonyms: malate Na(+) symporter activity; malate-sodium symporter activity; malate/sodium cotransporter activity; malate/sodium symporter activity; malate:Na+ symporter activity; malate:sodium cotransporter activity; Na(+)-malate symporter activity; Na+:malate symporter activity; sodium-dependent malate transporter; sodium/malate symporter activity; sodium:malate symporter activity
malolactic enzyme activity (GO:0043883)
Namespace: molecular_function
Definition: Catalysis of the reaction: (S)-malate + H+ = (S)-lactate + CO2.
Synonyms: MleS
Comment: This function is part of the process of degradation of L-malic acid by lactic acid bacteria.
obsolete (S)-3-O-geranylgeranylglyceryl phosphate synthase activity (GO:0043889)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction:(2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate.
Synonyms: (S)-3-O-geranylgeranylglycerylphosphate synthase activity; (S)-GGGP synthase activity; GGGP synthase activity; GGGPS
Comment: This function is involved in archaeal lipid synthesis. The reason for obsoletion is that this term is equivalent to GO:0047294 phosphoglycerol geranylgeranyltransferase activity.
glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity (GO:0043891)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.
Synonyms: D-glyceraldehyde 3-phosphate:NAD(P)+ oxidoreductase (phosphorylating); glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating); NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase activity; triosephosphate dehydrogenase (NAD(P)); triosephosphate dehydrogenase (NAD(P)+)
D-lysine:2-oxoglutarate transaminase activity (GO:0043911)
Namespace: molecular_function
Definition: Catalysis of the reaction: D-lysine + 2-oxoglutarate = 6-amino-2-oxohexanoate + L-glutamate.
Synonyms: D-lysine aminotransferase activity; D-lysine transaminase activity
aminopropylagmatine ureohydrolase activity (GO:0043920)
Namespace: molecular_function
Definition: Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.
obsolete primary ovarian follicle growth involved in double layer follicle stage (GO:0043929)
Namespace: biological_process
Definition: OBSOLETE. Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.
Synonyms: primary ovarian follicle growth during double layer follicle stage
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete positive regulation of catalytic activity in other organism involved in symbiotic interaction (GO:0043946)
Namespace: biological_process
Definition: OBSOLETE. Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
Synonyms: activation of enzyme activity in other organism; activation of enzyme activity in other organism during symbiotic interaction; positive regulation of catalytic activity in other organism during symbiotic interaction; up regulation of enzyme activity in other organism during symbiotic interaction; up-regulation of enzyme activity in other organism during symbiotic interaction; upregulation of enzyme activity in other organism during symbiotic interaction
Comment: This term was obsoleted because it represents a molecular function.
3-hydroxypropionyl-CoA dehydratase activity (GO:0043956)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-hydroxypropionyl-CoA = acryloyl-CoA + H2O.
Synonyms: 3-hydroxy propionyl-CoA dehydratase activity; acetyl-coenzyme A synthetase; acetyl-coenzyme A synthetase/GroES-like domain; AMP-dependent synthetase and ligase; AMP-dependent synthetase and ligase:Enoyl-CoA hydratase/isomerase; enoyl-CoA hydratase/isomerase
Comment: Note that this function is one of the activities of the trifunctional enzyme propionyl-coenzyme A synthase. See PMID:11821399.
obsolete histone H3 acetylation (GO:0043966)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H3 by the addition of an acetyl group.
Comment: This term was obsoleted because it represents a molecular function.
obsolete histone H4-K12 acetylation (GO:0043983)
Namespace: biological_process
Definition: OBSOLETE. The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
Synonyms: histone H4 acetylation at K12
Comment: This term was obsoleted because it represents a molecular function.
obsolete dissemination or transmission of symbiont from host by vector (GO:0044008)
Namespace: biological_process
Definition: OBSOLETE. The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: dissemination or transmission of organism from host by vector
Comment: This term was obsoleted because it did not represent a specific process, but represented the life cycle of a symbiont.
single-species biofilm formation on inanimate substrate (GO:0044011)
Namespace: biological_process
Definition: A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
obsolete DNA hypermethylation (GO:0044026)
Namespace: biological_process
Definition: OBSOLETE. An increase in the epigenetic methylation of cytosine and adenosine residues in DNA.
Comment: The reason for obsoletion is this is a readout.
obsolete multi-organism cell wall macromolecule metabolic process (GO:0044037)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
Synonyms: multi-organism cell wall macromolecule metabolism
Comment: This term was obsoleted because there is no evidence that this process exists.
regulation of monoatomic anion transport (GO:0044070)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms: regulation of anion transport
(3R)-citramalyl-CoA lyase activity (GO:0044101)
Namespace: molecular_function
Definition: Catalysis of the reaction: (3R)-citramalyl-CoA = pyruvate + acetyl-CoA.
Synonyms: Ccl; R-citramalyl-CoA lyase activity
L-arabinose 1-dehydrogenase (NADP+) activity (GO:0044103)
Namespace: molecular_function
Definition: Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.
obsolete growth involved in symbiotic interaction (GO:0044110)
Namespace: biological_process
Definition: OBSOLETE. The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.
Synonyms: growth during symbiotic interaction; growth on or near surface of other organism during symbiotic interaction; growth on or near surface of other organism involved in symbiotic interaction
Comment: This term has been obsoleted because it represents an assay for viability, not a real biological process.
positive regulation of development of symbiont in host (GO:0044129)
Namespace: biological_process
Definition: Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
Comment: This term partially replaces the obsolete term 'positive regulation of growth or development of symbiont in host ; GO:0033666'. See also 'positive regulation of growth of symbiont in host ; GO:0044128'.
obsolete negative regulation of formation of structure involved in a symbiotic process (GO:0044147)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
Synonyms: negative regulation of development of symbiont during interaction with host; negative regulation of development of symbiont involved in interaction with host
Comment: This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
obsolete growth of host on or near symbiont surface (GO:0044151)
Namespace: biological_process
Definition: OBSOLETE. The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
Synonyms: growth of organism on or near symbiont surface
Comment: This term was obsoleted because it represents both a process and a location.
host thylakoid membrane (GO:0044160)
Namespace: cellular_component
Definition: The pigmented membrane of any host thylakoid.
host cell endosome membrane (GO:0044175)
Namespace: cellular_component
Definition: The lipid bilayer surrounding a host cell endosome.
Synonyms: host endosome membrane