LiteFold/GO huggingface dataset:
exit from host cell (GO:0035891)
Namespace: biological_process
Definition: The movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: ejection from host; ejection from host cell; exit from host; host cell exit
response to immobilization stress (GO:0035902)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
Synonyms: response to immobilisation stress; response to restraint stress
dehydroepiandrosterone secretion (GO:0035942)
Namespace: biological_process
Definition: The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.
Synonyms: 3beta-hydroxyandrost-5-en-17-one secretion; dehydroisoandrosterone secretion; DHEA secretion
obsolete negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter (GO:0035952)
Namespace: biological_process
Definition: OBSOLETE. Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
Synonyms: negative regulation of oligopeptide transport by down regulation of transcription from RNA polymerase II promoter; negative regulation of oligopeptide transport by down-regulation of transcription from RNA polymerase II promoter; negative regulation of oligopeptide transport by downregulation of transcription from RNA polymerase II promoter; negative regulation of oligopeptide transport by inhibition of transcription from RNA polymerase II promoter; negative regulation of oligopeptide transport by negative regulation of transcription from Pol II promoter
Comment: This term was obsoleted because it represents a GO-CAM model.
COPI-coated vesicle budding (GO:0035964)
Namespace: biological_process
Definition: The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
Synonyms: COPI vesicle budding
tetrahydrofolate interconversion (GO:0035999)
Namespace: biological_process
Definition: The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesize other tetrahydrofolate molecules.
cellular response to macrophage colony-stimulating factor stimulus (GO:0036006)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
Synonyms: cellular response to M-CSF stimulus; cellular response to macrophage colony-stimulating factor
response to interleukin-3 (GO:0036015)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
Synonyms: response to IL-3
endolysosome (GO:0036019)
Namespace: cellular_component
Definition: An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.
endolysosome membrane (GO:0036020)
Namespace: cellular_component
Definition: The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.
Synonyms: endolysosomal membrane
protein C inhibitor-TMPRSS7 complex (GO:0036024)
Namespace: cellular_component
Definition: A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.
Synonyms: PCI-TMPRSS7 complex; plasma serine protease inhibitor-TMPRSS7 complex; protein C inhibitor-matriptase-3 complex; protein C inhibitor-transmembrane protease serine 7 complex; serpin A5-TMPRSS7 complex; SERPINA5-TMPRSS7 complex
protein C inhibitor-PLAU complex (GO:0036027)
Namespace: cellular_component
Definition: A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.
Synonyms: PCI-PLAU complex; plasma serine protease inhibitor-PLAU complex; protein C inhibitor-U-plasminogen activator complex; protein C inhibitor-uPA complex; protein C inhibitor-urokinase-type plasminogen activator complex; serpin A5-PLAU complex; SERPINA5-PLAU complex
MKS complex (GO:0036038)
Namespace: cellular_component
Definition: A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.
Synonyms: B9 complex; MKS module; TCTN-B9D complex; tectonic complex; tectonic-like complex
Comment: Although there is some evidence, it is still unclear if the MKS and NPHP complexes are constituents parts of the Y-shaped links or are simply responsible for aligning and attaching the Y-shaped links to the membrane and axoneme.
protein localization to trailing edge (GO:0036051)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.
Synonyms: protein localisation to trailing edge
muscle cell chemotaxis toward tendon cell (GO:0036061)
Namespace: biological_process
Definition: The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.
Synonyms: muscle cell attraction; muscle cell chemotaxis towards tendon cell
presynaptic periactive zone (GO:0036062)
Namespace: cellular_component
Definition: A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.
Synonyms: periactive zone; pre-synaptic periactive zone
light-dependent bacteriochlorophyll biosynthetic process (GO:0036069)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
Synonyms: light dependent bacteriochlorophyll biosynthetic process; light-dependent bacteriochlorophyll anabolism; light-dependent bacteriochlorophyll biosynthesis; light-dependent bacteriochlorophyll formation; light-dependent bacteriochlorophyll synthesis
light-independent bacteriochlorophyll biosynthetic process (GO:0036070)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
Synonyms: light independent bacteriochlorophyll biosynthetic process; light-independent bacteriochlorophyll anabolism; light-independent bacteriochlorophyll biosynthesis; light-independent bacteriochlorophyll formation; light-independent bacteriochlorophyll synthesis
metaplastic ossification (GO:0036074)
Namespace: biological_process
Definition: Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.
Synonyms: metaplasia
Comment: Some intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division.
purine nucleotide-sugar transmembrane transporter activity (GO:0036080)
Namespace: molecular_function
Definition: Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
extracellular phenylacetaldehyde-gated monoatomic ion channel activity (GO:0036082)
Namespace: molecular_function
Definition: Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.
Synonyms: extracellular phenylacetaldehyde-gated ion channel activity; ionotropic phenylacetaldehyde receptor activity
obsolete positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0036091)
Namespace: biological_process
Definition: OBSOLETE. Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
Comment: This term was obsoleted because it represents a GO-CAM model.
male germ-line stem cell population maintenance (GO:0036098)
Namespace: biological_process
Definition: The process by which an organism or tissue maintains a population of male germ-line stem cells.
obsolete Kdo2-lipid A metabolic process (GO:0036103)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.
Synonyms: Kdo2-lipid A metabolism
Comment: This term was obsoleted because it is an unnecessary grouping term.
peroxisome membrane class-1 targeting sequence binding (GO:0036105)
Namespace: molecular_function
Definition: Binding to a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
Synonyms: class 1 mPTS binding; PEX19-dependent mPTS binding
Comment: Currently identified mPTSs vary greatly in length, and cannot be distinguished by primary structure analysis, suggesting that the peroxisomal sorting information is not contained within a specific amino acid sequence. There do however appear to be two classes of mPTSs: class 1 mPTSs that are bound by PEX19 and imported in a PEX19-dependent manner, and class 2 mPTSs that are not bound by PEX19 and mediate protein import independently of PEX19. The two classes cannot be defined based on their amino acid sequence.
obsolete 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process (GO:0036107)
Namespace: biological_process
Definition: OBSOLETE. The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
Synonyms: 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate metabolic process; undecaprenyl phosphate alpha-L-Ara4N metabolism
Comment: This term was obsoleted because it is an unnecessary grouping class.
Schwann cell migration (GO:0036135)
Namespace: biological_process
Definition: The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function.
obsolete L-phenylalanine-oxaloacetate transaminase activity (GO:0036141)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate.
Synonyms: L-phenylalanine:oxaloacetate transaminase activity
Comment: This term was obsoleted because it represents the same activity as L-phenylalanine-2-oxoglutarate transaminase activity ; GO:0080130.
calcitonin secretion (GO:0036161)
Namespace: biological_process
Definition: The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.
cell-abiotic substrate adhesion (GO:0036164)
Namespace: biological_process
Definition: The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.
Synonyms: cell-abiotic surface adhesion
response to neutral pH (GO:0036176)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
abieta-7,13-dien-18-al (NAD+) dehydrogenase activity (GO:0036188)
Namespace: molecular_function
Definition: Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.
Synonyms: abieta-7,13-dien-18-al dehydrogenase activity; abietadienal dehydrogenase
abieta-7,13-diene hydroxylase activity (GO:0036189)
Namespace: molecular_function
Definition: Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.
Synonyms: abietadiene hydroxylase
indolin-2-one monooxygenase activity (GO:0036191)
Namespace: molecular_function
Definition: Catalysis of the reaction: ndolin-2-one + reduced [NADPH-hemoprotein reductase] + O2 = 3-hydroxyindolin-2-one + oxidized [NADPH-hemoprotein reductase] + H2O + H+.
Synonyms: indolin-2-one,NAD(P)H:oxygen oxidoreductase (3-hydroxylating)
3-hydroxyindolin-2-one monooxygenase activity (GO:0036192)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-hydroxyindolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].
Synonyms: 3-hydroxyindolin-2-one,NAD(P)H:oxygen oxidoreductase (2-hydroxy-2H-1,4-benzoxazin-3(4H)-one-forming)
muscle cell projection membrane (GO:0036195)
Namespace: cellular_component
Definition: The portion of the plasma membrane surrounding a muscle cell projection.
abieta-7,13-dien-18-ol hydroxylase activity (GO:0036204)
Namespace: molecular_function
Definition: Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.
obsolete protein modification process in another organism (GO:0036210)
Namespace: biological_process
Definition: OBSOLETE. The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
Synonyms: protein modification in other organism; protein modification process in other organism
Comment: This term was obsoleted because it represents a readout.
contractile ring contraction (GO:0036213)
Namespace: biological_process
Definition: The process of an actomyosin ring getting smaller in diameter.
Synonyms: contractile ring constriction
Comment: This term can be used to annotate contraction of either bacterial or fungal contractile rings.
dGTP diphosphatase activity (GO:0036217)
Namespace: molecular_function
Definition: Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.
Synonyms: 2'-deoxyguanosine 5'-triphosphate diphosphohydrolase; dGTP pyrophosphatase activity
protein localization to nuclear inner membrane (GO:0036228)
Namespace: biological_process
Definition: A process in which a protein is transported to, or maintained in, a location within the nuclear inner membrane.
Synonyms: protein targeting to INM; protein targeting to nuclear inner membrane
phytochelatin 2 import into vacuole (GO:0036246)
Namespace: biological_process
Definition: The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
Synonyms: PC2 import into vacuole
cellular response to decreased oxygen levels (GO:0036294)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
Synonyms: cellular response to lowered oxygen levels
Comment: This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'cellular response to hypoxia ; GO:0071456'.
phosphatidylinositol 3-kinase regulatory subunit binding (GO:0036312)
Namespace: molecular_function
Definition: Binding to a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.
Synonyms: p85 binding; PI3K regulatory subunit binding
cellular response to sterol (GO:0036315)
Namespace: biological_process
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
pancreatic polypeptide secretion (GO:0036322)
Namespace: biological_process
Definition: The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.
Synonyms: PP secretion
bacteriochlorophyllide-a dehydrogenase activity (GO:0036354)
Namespace: molecular_function
Definition: Catalysis of the reaction: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD+ = bacteriochlorophyllide a + NADH + H+.
Synonyms: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity
obsolete racemase activity, acting on amino acids and derivatives (GO:0036361)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.
Comment: The reason for obsoletion is that this term was an unnecessary grouping term.
ascus membrane (GO:0036362)
Namespace: cellular_component
Definition: A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.
obsolete transforming growth factor beta2 activation (GO:0036365)
Namespace: biological_process
Definition: OBSOLETE. The release of transforming growth factor beta 2 (TGF-beta2) from its latent state.
Synonyms: TGF-beta 2 activation; TGFB2 activation; TGFbeta 2 activation
Comment: The reason for obsoletion is that this represents a molecular function.
CDP phosphatase activity (GO:0036384)
Namespace: molecular_function
Definition: Catalysis of the reaction: CDP + H2O = CMP + phosphate.
Synonyms: CDP diphosphatase activity; CDPase activity; cytidine diphosphatase activity; cytidine-diphosphatase activity
obsolete nucleoid DNA packaging (GO:0036385)
Namespace: biological_process
Definition: OBSOLETE. Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.
Comment: This term was obsoleted because it is an unnecessary grouping class.
amylase secretion (GO:0036394)
Namespace: biological_process
Definition: The controlled release of amylase from a cell.
Synonyms: amylase release
pyrokinin receptor activity (GO:0036401)
Namespace: molecular_function
Definition: Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.
Synonyms: PK receptor activity
arachidonate 8(S)-lipoxygenase activity (GO:0036403)
Namespace: molecular_function
Definition: Catalysis of the reaction: arachidonate + O2 = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
Synonyms: 8(S)-lipoxygenase activity; 8-lipoxygenase (S-type)
Comment: This activity produces the S-enantiomer of HPETE, 8(S)-HPETE. For the reaction producing the S-enantiomer, see GO:0047677.
tRNA stabilization (GO:0036416)
Namespace: biological_process
Definition: Prevention of degradation of tRNA molecules.
obsolete ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity (GO:0036426)
Namespace: molecular_function
Definition: OBSOLETE. Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.
Comment: This term was obsoleted because it represents a specific substrate.
ESCRT complex (GO:0036452)
Namespace: cellular_component
Definition: An endosomal sorting complex involved in membrane fission processes related to sorting of multivesicular bodies (MVB) in the endocytic pathway, cytokinesis and viral budding among other processes.
Synonyms: endosomal sorting complex required for transport
TRAIL receptor activity (GO:0036463)
Namespace: molecular_function
Definition: Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.
Synonyms: tumor necrosis factor-related apoptosis-inducing ligand receptor
obsolete suppression by virus of host protein-protein interaction (GO:0036472)
Namespace: biological_process
Definition: OBSOLETE. Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins.
Synonyms: suppression by virus of host protein binding; suppression by virus of host protein interaction; suppression by virus of host protein:protein binding; suppression by virus of host protein:protein interaction
Comment: This term was obsoleted because it represents a molecular function.
obsolete neuron death in response to hydrogen peroxide (GO:0036476)
Namespace: biological_process
Definition: OBSOLETE. Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2).
Synonyms: hydrogen peroxide-induced neuron death; neuron death in response to H2O2; neuronal cell death in response to hydrogen peroxide
Comment: The reason for obsoletion is that this term represent an assay or a phenotype.
CHOP-C/EBP complex (GO:0036488)
Namespace: cellular_component
Definition: A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.
Synonyms: CHOP-C/EBP dimer; CHOP-C/EBP heterodimer; GADD153-C/EBP complex; GADD153-C/EBP-alpha complex
protein demannosylation (GO:0036507)
Namespace: biological_process
Definition: The removal of one or more mannose residues from a mannosylated protein.
Synonyms: protein de-mannosylation
Comment: Consider also annotating to the term 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.
trimming of terminal mannose on C branch (GO:0036510)
Namespace: biological_process
Definition: The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
Synonyms: conversion of (Man)9(GlcNAc)2 to (Man)8C(GlcNAc)2; conversion of M9 to M8C; glycoprotein mannose trimming on C branch
Comment: Consider also annotating to 'mannosyl-oligosaccharide 1,2-alpha-mannosidase activity ; GO:0004571'.