LiteFold/GO huggingface dataset:
paclitaxel biosynthetic process (GO:0042617)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.
Synonyms: paclitaxel anabolism; paclitaxel biosynthesis; paclitaxel formation; paclitaxel metabolic process; paclitaxel metabolism; paclitaxel synthesis; taxol biosynthesis; taxol biosynthetic process; taxol metabolic process; taxol metabolism
positive regulation of hair cycle (GO:0042635)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
Synonyms: activation of hair cycle; stimulation of hair cycle; up regulation of hair cycle; up-regulation of hair cycle; upregulation of hair cycle
chloroplast nucleoid (GO:0042644)
Namespace: cellular_component
Definition: The region of a chloroplast to which the DNA is confined.
obsolete mitochondrial respiratory chain complex I, peripheral segment (GO:0042652)
Namespace: cellular_component
Definition: OBSOLETE. The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.
Synonyms: NADH dehydrogenase (ubiquinone) complex, peripheral segment; NADH-Q oxidoreductase complex, peripheral segment
Comment: The reason for obsoletion is that this term represents a sub-complex, out-of-scope for GO.
regulation of ectodermal cell fate specification (GO:0042665)
Namespace: biological_process
Definition: Any process that mediates the specification of a cell into an ectoderm cell.
Synonyms: regulation of ectoderm cell fate specification
regulation of retinal cone cell fate specification (GO:0042673)
Namespace: biological_process
Definition: Any process that mediates the specification of a cell into a retinal cone cell.
crystal cell differentiation (GO:0042688)
Namespace: biological_process
Definition: The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
ovulation cycle (GO:0042698)
Namespace: biological_process
Definition: The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
dosage compensation complex assembly (GO:0042714)
Namespace: biological_process
Definition: The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.
flavin-containing compound biosynthetic process (GO:0042727)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
Synonyms: flavin-containing compound anabolism; flavin-containing compound biosynthesis; flavin-containing compound formation; flavin-containing compound synthesis; riboflavin and derivative biosynthesis; riboflavin and derivative biosynthetic process; vitamin B2 and derivative biosynthesis; vitamin B2 and derivative biosynthetic process
DASH complex (GO:0042729)
Namespace: cellular_component
Definition: A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the outer kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
Synonyms: condensed nuclear chromosome kinetochore-associated DASH complex; Dam1 complex; DDD complex; Duo1p-Dam1p-Dad1p complex
Comment: Note that this complex is conserved in fungi but has not been observed in metazoans.
endogenous antibiotic catabolic process (GO:0042741)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.
Synonyms: endogenous antibiotic breakdown; endogenous antibiotic catabolism; endogenous antibiotic degradation
defense response to bacterium (GO:0042742)
Namespace: biological_process
Definition: Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
Synonyms: antibacterial peptide activity; defence response to bacteria; defence response to bacterium; defense response to bacteria; defense response to bacterium, incompatible interaction; resistance response to pathogenic bacteria; resistance response to pathogenic bacterium
regulation of circadian rhythm (GO:0042752)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
proton motive force-driven mitochondrial ATP synthesis (GO:0042776)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of ATP driven by transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force).
Synonyms: mitochondrial ATP synthesis coupled proton transport; mitochondrial proton transport
tRNA 3'-end processing (GO:0042780)
Namespace: biological_process
Definition: The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
Synonyms: tRNA 3' processing
obsolete evasion of host immune response via modulation of host antigen processing and presentation (GO:0042786)
Namespace: biological_process
Definition: OBSOLETE. Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
Synonyms: active evasion of host immune response via regulation of host antigen processing and presentation; active evasion of host immune response via regulation of host antigen processing and presentation pathway; active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction; active immune evasion via modulation of antigen processing and presentation; active immune evasion via modulation of antigen processing/presentation; active immune evasion via regulation of antigen processing and presentation; evasion of host immune response via regulation of host antigen processing and presentation
Comment: This term was obsoleted because it represents the same process as symbiont-mediated suppression of host antigen processing and presentation ; GO:0039588.
Wnt receptor activity (GO:0042813)
Namespace: molecular_function
Definition: Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Synonyms: frizzled receptor activity; frizzled-2 receptor activity; Wnt-activated receptor activity
vitamin B6 metabolic process (GO:0042816)
Namespace: biological_process
Definition: The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
Synonyms: vitamin B6 metabolism
pyridoxamine metabolic process (GO:0042818)
Namespace: biological_process
Definition: The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
Synonyms: pyridoxamine metabolism
D-xylose biosynthetic process (GO:0042842)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.
Synonyms: D-xylose anabolism; D-xylose biosynthesis; D-xylose formation; D-xylose synthesis
L-sorbose catabolic process (GO:0042850)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.
Synonyms: L-sorbose breakdown; L-sorbose catabolism; L-sorbose degradation
achromobactin biosynthetic process (GO:0042861)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.
Synonyms: achromobactin anabolism; achromobactin biosynthesis; achromobactin formation; achromobactin synthesis
pyochelin catabolic process (GO:0042865)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
Synonyms: pyochelin breakdown; pyochelin catabolism; pyochelin degradation
obsolete peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein (GO:0042902)
Namespace: biological_process
Definition: OBSOLETE. The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
Comment: This term was obsoleted because it represents a molecular function.
achromobactin transport (GO:0042935)
Namespace: biological_process
Definition: The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
tripeptide transport (GO:0042939)
Namespace: biological_process
Definition: The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
arbutin transmembrane transporter activity (GO:0042951)
Namespace: molecular_function
Definition: Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of a membrane to the other.
dextrin transport (GO:0042955)
Namespace: biological_process
Definition: The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
maltodextrin transmembrane transport (GO:0042956)
Namespace: biological_process
Definition: The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, across a membrane.
Synonyms: maltodextrin transport
acridine:proton antiporter activity (GO:0042962)
Namespace: molecular_function
Definition: Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).
Synonyms: acridine efflux pump activity; acridine:hydrogen antiporter activity
ornithine decarboxylase regulator activity (GO:0042979)
Namespace: molecular_function
Definition: Binds to and modulates the activity of the enzyme ornithine decarboxylase.
amyloid precursor protein catabolic process (GO:0042987)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.
Synonyms: amyloid precursor protein breakdown; amyloid precursor protein catabolism; amyloid precursor protein degradation; APP catabolic process; APP catabolism
obsolete sequestering of actin monomers (GO:0042989)
Namespace: biological_process
Definition: OBSOLETE. The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.
Synonyms: actin monomer retention; actin monomer sequestering; actin monomer sequestration; actin monomer storage; retention of actin monomers; sequestration of actin monomers; storage of actin monomers
Comment: The reason for obsoletion is that this term represents a molecular function, not biological process
obsolete regulation of transcription factor import into nucleus (GO:0042990)
Namespace: biological_process
Definition: OBSOLETE. Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
Synonyms: regulation of transcription factor import into cell nucleus; regulation of transcription factor transport from cytoplasm to nucleus; regulation of transcription factor-nucleus import
Comment: The reason for obsoletion is that there is no distinct pathway to import transcription factors into the nucleus.
costamere (GO:0043034)
Namespace: cellular_component
Definition: Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.
chromatin insulator sequence binding (GO:0043035)
Namespace: molecular_function
Definition: Binding to a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
starch grain (GO:0043036)
Namespace: cellular_component
Definition: Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
Synonyms: starch granule
forward locomotion (GO:0043056)
Namespace: biological_process
Definition: Anterior movement of an organism, following the direction of the head of the animal.
positive regulation of programmed cell death (GO:0043068)
Namespace: biological_process
Definition: Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
Synonyms: activation of programmed cell death; positive regulation of non-apoptotic programmed cell death; stimulation of programmed cell death; up regulation of programmed cell death; up-regulation of programmed cell death; upregulation of programmed cell death
megasporocyte nucleus (GO:0043076)
Namespace: cellular_component
Definition: The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.
Synonyms: megaspore mother cell nucleus
synaptic cleft (GO:0043083)
Namespace: cellular_component
Definition: The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
receptor metabolic process (GO:0043112)
Namespace: biological_process
Definition: The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
Synonyms: receptor metabolism
hindgut contraction (GO:0043133)
Namespace: biological_process
Definition: A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.
5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity (GO:0043135)
Namespace: molecular_function
Definition: Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.
Synonyms: PRPP pyrophosphatase activity
DNA replication, removal of RNA primer (GO:0043137)
Namespace: biological_process
Definition: Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
Synonyms: Okazaki initiator RNA removal
5'-3' DNA helicase activity (GO:0043139)
Namespace: molecular_function
Definition: Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.
Synonyms: 5' to 3' DNA helicase activity; ATP-dependent 5' to 3' DNA helicase activity; ATP-dependent 5'-3' DNA helicase activity; DNA helicase IV activity
induction of bacterial agglutination (GO:0043152)
Namespace: biological_process
Definition: Any process in which infecting bacteria are clumped together by a host organism.
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162)
Namespace: biological_process
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
Synonyms: ubiquitin-dependent protein breakdown via the multivesicular body pathway; ubiquitin-dependent protein catabolic process via the MVB pathway; ubiquitin-dependent protein catabolism via the MVB pathway; ubiquitin-dependent protein degradation via the multivesicular body pathway
cell envelope organization (GO:0043163)
Namespace: biological_process
Definition: A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.
Synonyms: cell envelope organisation; cell envelope organization and biogenesis
anion binding (GO:0043168)
Namespace: molecular_function
Definition: Binding to an anion, a charged atom or group of atoms with a net negative charge.
nucleoside salvage (GO:0043174)
Namespace: biological_process
Definition: Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.
dendritic spine (GO:0043197)
Namespace: cellular_component
Definition: A small, membranous protrusion from a dendrite that forms a postsynaptic compartment, typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable:they can be thin, stubby, mushroom, or branched, with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Synonyms: branched dendritic spine; dendrite spine; mushroom dendritic spine; sessile dendritic spine; stubby dendritic spine; thin dendritic spine
compact myelin (GO:0043218)
Namespace: cellular_component
Definition: The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.
Synonyms: oligodendrocyte compact myelin; Schwann cell compact myelin
megasome (GO:0043246)
Namespace: cellular_component
Definition: Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.
extracellular membraneless organelle (GO:0043264)
Namespace: cellular_component
Definition: Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.
Synonyms: extracellular non-membrane-bounded organelle; extracellular non-membrane-enclosed organelle
regulation of poly(3-hydroxyalkanoate) biosynthetic process (GO:0043286)
Namespace: biological_process
Definition: Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
Synonyms: regulation of PHA; regulation of poly(3-hydroxyalkanoate) anabolism; regulation of poly(3-hydroxyalkanoate) biosynthesis; regulation of poly(3-hydroxyalkanoate) formation; regulation of poly(3-hydroxyalkanoate) synthesis
mast cell degranulation (GO:0043303)
Namespace: biological_process
Definition: The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
Synonyms: mast cell granule exocytosis
cardiolipin synthase (CMP-forming) activity (GO:0043337)
Namespace: molecular_function
Definition: Catalysis of the reaction: a CDP-1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + CMP + H+.
Synonyms: cardiolipin synthase; cardiolipin synthetase; CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity
memory T cell differentiation (GO:0043379)
Namespace: biological_process
Definition: The process in which a newly activated T cell acquires specialized features of a memory T cell.
Synonyms: memory T cell development; memory T lymphocyte differentiation; memory T-cell differentiation; memory T-lymphocyte differentiation
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
cortisol secretion (GO:0043400)
Namespace: biological_process
Definition: The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.
Synonyms: hydrocortisone secretion
negative regulation of MAPK cascade (GO:0043409)
Namespace: biological_process
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
Synonyms: down regulation of MAPK cascade; down regulation of MAPKKK cascade; down-regulation of MAPK cascade; down-regulation of MAPKKK cascade; downregulation of MAPK cascade; downregulation of MAPKKK cascade; inhibition of MAPK cascade; inhibition of MAPKKK cascade; negative regulation of MAP kinase cascade; negative regulation of MAP kinase kinase kinase cascade; negative regulation of MAPKKK cascade; negative regulation of mitogen activated protein kinase cascade; negative regulation of mitogen activated protein kinase kinase kinase cascade; negative regulation of mitogen-activated protein kinase cascade; negative regulation of mitogen-activated protein kinase kinase kinase cascade
macromolecule modification (GO:0043412)
Namespace: biological_process
Definition: The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
obsolete macromolecule glycosylation (GO:0043413)
Namespace: biological_process
Definition: OBSOLETE. The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
Comment: The reason for obsoletion is that the term is not clearly defined and usage has been inconsistent.