Protein: Spectrin alpha chain, non-erythrocytic 1 (Homo sapiens)
UniProt: Q13813
Mutation: I2374Q
PDB: 5FWB
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.889780951949516
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)