Protein: Rap guanine nucleotide exchange factor 2 (Homo sapiens)
UniProt: Q9Y4G8
Mutation: I461Y
Experiment dataset: Domainome DDG
Domainome ddG: 0.599639635818641
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)