Protein: POU domain, class 3, transcription factor 1 (Homo sapiens)
UniProt: Q03052
Mutation: D253S
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.476598395787565
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)