Protein: E3 ubiquitin-protein ligase ARK2C (Homo sapiens)
UniProt: Q6ZSG1
EC number: 2.3.2.27
Mutation: V321R
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.256542869629502
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)