Protein: POU domain, class 2, transcription factor 1 (Homo sapiens)
UniProt: P14859
Mutation: S335I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.801328673601719
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)