Protein: E3 ubiquitin-protein ligase SH3RF3 (Homo sapiens)
UniProt: Q8TEJ3
EC number: 2.3.2.27
Mutation: I221E
Experiment dataset: Domainome DDG
Domainome ddG: 0.933169069054423
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)