Protein: SAM and SH3 domain-containing protein 1 (Homo sapiens)
UniProt: O94885
Mutation: N646Y
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.904334288342837
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)