Protein: Tyrosine-protein kinase Fyn (Homo sapiens)
UniProt: P06241
EC number: 2.7.10.2
Mutation: E107L|S124A
PDB: 1A0N|1SHF
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 8
Buffer: Tris-HCl 10 mM
Ion: KCl 250 mM
Tm: 51.4
dTm: -28.7
dHvH: 24.3
Reversibility: yes
Reference: Mutagenesis of a buried polar interaction in an SH3 domain: sequence conservation provides the best prediction of stability effects. — Davidson A R|Maxwell K L (Biochemistry;37;16172-82, 1998)