Protein: Histone-lysine N-methyltransferase PRDM16 (Homo sapiens)
UniProt: Q9HAZ2
EC number: 2.1.1.367
Mutation: M289L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.152906363645276
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)