Protein: 3-isopropylmalate dehydrogenase (Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7))
UniProt: P50455
EC number: 1.1.1.85
Mutation: M91L|I95L
PDB: 1WPW
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: Potassium phosphate 20 mM
Tm: 99.2
dTm: 3.2
Reversibility: Unknown
Reference: Ancestral residues stabilizing 3-isopropylmalate dehydrogenase of an extreme thermophile: experimental evidence supporting the thermophilic common ancestor hypothesis. — Suzuki T|Yamagishi A|Oshima T|Miyazaki J|Nakaya S|Tamakoshi M (J Biochem;129;777-82, 2001)