Protein: Tyrosine-protein kinase BTK (Homo sapiens)
UniProt: Q06187
EC number: 2.7.10.2
Mutation: A221I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.965741248666316
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)