Protein: Rho guanine nucleotide exchange factor TIAM1 (Homo sapiens)
UniProt: Q13009
Mutation: I870V
Experiment dataset: Domainome FITNESS
Domainome fitness: 0.00839946640412699
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)