Protein: Lysine-specific histone demethylase 2 (Homo sapiens)
UniProt: Q8NB78
EC number: 1.14.99.66
Mutation: I177N
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.325784780648985
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)