Protein: Beta-lactamase TEM (Escherichia coli)
UniProt: P62593
EC number: 3.5.2.6
Mutation: E102K|M180T
PDB: 1AXB|1BTL
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: potassium phosphate buffer 200000.0
Tm: 61.7
dTm: 5.28
dG: -9
ddG: 1.5
dHvH: -80
Reversibility: yes
State: 2.0
Reference: Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 ?-Lactamase. — Knies Jennifer L|Cai Fei|Weinreich Daniel M (Mol Biol Evol;34;1040-1054, 2017)