Protein: POU domain, class 4, transcription factor 2 (Homo sapiens)
UniProt: Q12837
Mutation: I270E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.226272432696442
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)