Protein: Tissue-type plasminogen activator (Homo sapiens)
UniProt: P00750
EC number: 3.4.21.68
Mutation: Y290K
PDB: 1PML|1TPK
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 8
Buffer: Tris - Oac/100mM NaOAc 50 mM
Tm: 61.7
dTm: -13.9
Reversibility: Unknown
State: 2.0
Reference: Involvement of tyrosine-76 of the kringle 2 domain of tissue-type plasminogen activator in its thermal stability and its omega-amino acid ligand binding site. — De Serrano V S (Biochemistry;33;3509-14, 1994)