Protein: POU domain, class 4, transcription factor 3 (Homo sapiens)
UniProt: Q15319
Mutation: S222Y
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0549631006670164
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)