Protein: Pre-mRNA-processing factor 40 homolog B (Homo sapiens)
UniProt: Q6NWY9
Mutation: S274W
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.416964707124962
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)