Protein: Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (Homo sapiens)
UniProt: P11182
EC number: 2.3.1.168
Mutation: I186H
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.678549018042536
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)