Protein: Tyrosine-protein kinase ITK/TSK (Homo sapiens)
UniProt: Q08881
EC number: 2.7.10.2
Mutation: V221Y
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.923838805895814
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)