Protein: Guanylyl cyclase-activating protein 1 (Homo sapiens)
UniProt: P43080
Mutation: G86R|W94F
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7.5
Buffer: Tris-HCl 20mM
Ion: KCL and Mg2+ 150 mM and 1 mM
Tm: 47.8
dTm: -2.5
Reference: Constitutive Activation of Guanylate Cyclase by the G86R GCAP1 Variant Is Due to "Locking" Cation-? Interactions that Impair the Activator-to-Inhibitor Structural Transition. — Marino Valerio|Koch Karl-Wilhelm|Dell'Orco Daniele|Abbas Seher|Bielefeld Laura (Int J Mol Sci;21;, 2020)