Protein: Superoxide dismutase [Mn], mitochondrial (Homo sapiens)
UniProt: P04179
EC number: 1.15.1.1
Mutation: I82T
PDB: 1N0J
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 7.8
Buffer: Potassium phosphate 2 mM
Tm: 56.4
dTm: -13.6
dH: 64.9
Reversibility: yes
Reference: Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface. — Boissinot M|Hickey M J|Borgstahl G E|Parge H E|Johnson M J (Biochemistry;35;4287-97, 1996)