Protein: Transcriptional repressor p66-beta (Homo sapiens)
UniProt: Q8WXI9
Mutation: K451R
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0742858255482551
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)