Protein: Tyrosine-protein kinase BTK (Homo sapiens)
UniProt: Q06187
EC number: 2.7.10.2
Mutation: A221F
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.598728830630172
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)