Protein: Disks large homolog 4 (Homo sapiens)
UniProt: P78352
Mutation: A133I
PDB: 3K82
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0599797835506493
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)