Protein: E3 ubiquitin-protein ligase TRIM21 (Homo sapiens)
UniProt: P19474
EC number: 2.3.2.27
Mutation: D106I
Experiment dataset: Domainome DDG
Domainome ddG: 0.999897669346678
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)