Protein: Dystrophin (Homo sapiens)
UniProt: P11532
Experiment dataset: ProTherm
Method: Urea
Measure: CD
pH: 7
Buffer: sodium phosphate 0.1 M
Ion: NaCl 0.15 M
dG: 11.2
Reversibility: yes
State: 2.0
Reference: Missense mutation Lys18Asn in dystrophin that triggers X-linked dilated cardiomyopathy decreases protein stability, increases protein unfolding, and perturbs protein structure, but does not affect protein function. — Singh Surinder M|Mallela Krishna M G|Bandi Swati|Shah Dinen D|Armstrong Geoffrey (PLoS One;9;e110439, 2014)