Protein: Segment polarity protein dishevelled homolog DVL-1 (Homo sapiens)
UniProt: O14640
Mutation: E12I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.654220770880035
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)