Protein: Histone acetyltransferase p300 (Homo sapiens)
UniProt: Q09472
EC number: 2.3.1.48
Mutation: K586L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.474960806645718
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)