Protein: RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens)
UniProt: P04049
EC number: 2.7.11.1
Mutation: I58E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.798190910511472
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)