Protein: Protein THO1 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
UniProt: P40040
Mutation: L12D
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.393947440607905
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)