Protein: Beta-lactamase TEM (Escherichia coli)
UniProt: P62593
EC number: 3.5.2.6
Mutation: A40G|E102K|M180T
PDB: 1AXB|1BTL
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: potassium phosphate buffer 200000.0
Tm: 63.2
dTm: 6.78
dG: -11.8
ddG: 4.3
dHvH: -100
Reversibility: yes
State: 2.0
Reference: Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 ?-Lactamase. — Knies Jennifer L|Cai Fei|Weinreich Daniel M (Mol Biol Evol;34;1040-1054, 2017)