Protein: Transcriptional repressor p66-beta (Homo sapiens)
UniProt: Q8WXI9
Mutation: N448I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0884132846800369
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)