Protein: E3 ubiquitin-protein ligase makorin-2 (Homo sapiens)
UniProt: Q9H000
EC number: 2.3.2.27
Mutation: Y53W
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.220953155481081
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)