Protein: Lysine-specific histone demethylase 1A (Homo sapiens)
UniProt: O60341
EC number: 1.14.99.66
Mutation: H253M
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.440609835710024
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)