Protein: Cellular tumor antigen p53 (Homo sapiens)
UniProt: P04637
Mutation: M133L|V203A|N239Y|N268D
PDB: 2V5W|1TUP|1SAK
Experiment dataset: ProTherm
Method: Urea
Measure: Fluorescence
pH: 7.2
Buffer: Sodium phosphate 25 mM
Temperature: 37
Ion: Potassium chloride 150 mM
Cm: 2.56
m-value: -2.48
Reversibility: Yes
Reference: Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core. — Fersht Alan R|Khoo Kian Hoe|Joerger Andreas C|Freund Stefan M V (Protein Eng Des Sel;22;421-30, 2009)