Protein: Gamma-crystallin D (Homo sapiens)
UniProt: P07320
Mutation: G61C
PDB: 1HK0
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: PBS 10000.0
Tm: 73.9
dTm: -6.1
Reversibility: yes
State: 2.0
Reference: The congenital cataract-linked G61C mutation destabilizes ?D-crystallin and promotes non-native aggregation. — Yan Yong-Bin|Zhang Wang|Cai Hong-Chen|Li Fei-Feng|Xi Yi-Bo|Ma Xu (PLoS One;6;e20564, 2011)