Protein: U4/U6 small nuclear ribonucleoprotein Prp3 (Homo sapiens)
UniProt: O43395
Mutation: K12Y
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.216879309894717
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)