Protein: Cellular tumor antigen p53 (Homo sapiens)
UniProt: P04637
Mutation: M133L|V203A|N239Y|N268D|Y236F|T253I
PDB: 2V5W|1TUP|1SAK
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 7.2
Buffer: Sodium phosphate 25 mM
Ion: NaCl 150 mM
Tm: 51.3
dTm: 6
Reversibility: No
Reference: Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core. — Fersht Alan R|Khoo Kian Hoe|Joerger Andreas C|Freund Stefan M V (Protein Eng Des Sel;22;421-30, 2009)