Protein: Ubiquitin-protein ligase E3A (Homo sapiens)
UniProt: Q05086
EC number: 2.3.2.26
Mutation: E74D
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.19912031518655
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)