Protein: Histone acetyltransferase p300 (Homo sapiens)
UniProt: Q09472
EC number: 2.3.1.48
Mutation: R580L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.83718682629243
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)