Protein: Epidermal growth factor receptor kinase substrate 8 (Homo sapiens)
UniProt: Q12929
Mutation: R545I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0897257080252396
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)