Protein: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Geobacillus stearothermophilus)
UniProt: P11961
EC number: 2.3.1.12
Mutation: I146E
PDB: 1W3D|3DV0|1W4E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0718321814630473
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)