Protein: Ubiquitin-conjugating enzyme E2 K (Homo sapiens)
UniProt: P61086
EC number: 2.3.2.23
Mutation: D175M
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.798847777173613
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)