Protein: E3 ubiquitin-protein ligase RSP5 (Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
UniProt: P39940
EC number: 2.3.2.26
Mutation: W359I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.25802553817508
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)