Protein: Pre-mRNA-processing factor 40 homolog A (Homo sapiens)
UniProt: O75400
Mutation: M421R
PDB: 1UZC
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.460356915466527
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)