Protein: Histone deacetylase 8 (Homo sapiens)
UniProt: Q9BY41
EC number: 3.5.1.98
Mutation: I243N
PDB: 2V5W
Experiment dataset: ProTherm
Method: Thermal
Measure: fluorescence
pH: 7.5
Buffer: Hepes 25 mM
Ion: KCl 150 mM
Tm: 48.4
Reversibility: Unknown
Reference: Compromised structure and function of HDAC8 mutants identified in Cornelia de Lange Syndrome spectrum disorders. — Decroos Christophe|Bowman Christine M|Moser Joe-Ann S|Christianson Karen E|Deardorff Matthew A|Christianson David W (ACS Chem Biol;9;2157-64, 2014)