Protein: Mitogen-activated protein kinase kinase kinase 20 (Homo sapiens)
UniProt: Q9NYL2
EC number: 2.7.11.25
Mutation: E405W
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.33595287479591
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)