Protein: Connector enhancer of kinase suppressor of ras 2 (Homo sapiens)
UniProt: Q8WXI2
Mutation: R46L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.376560613831822
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)