Protein: Rho guanine nucleotide exchange factor 4 (Homo sapiens)
UniProt: Q9NR80
Mutation: I221Y
Experiment dataset: Domainome DDG
Domainome ddG: 0.587526820760568
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)