Protein: Gamma-crystallin S (Homo sapiens)
UniProt: P22914
Mutation: I161Y
PDB: 6FD8
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.200387277875427
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)