Protein: POU domain, class 3, transcription factor 4 (Homo sapiens)
UniProt: P49335
Mutation: E286I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.356640771800023
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)