Protein: Homeobox protein SIX4 (Homo sapiens)
UniProt: Q9UIU6
Mutation: R274P
Experiment dataset: Domainome DDG
Domainome ddG: 0.77812215210133
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)