Protein: Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens)
UniProt: Q5S007
EC number: 2.7.11.1|3.6.5.-
Mutation: G2385R
PDB: 6DLO
Experiment dataset: ProTherm
Method: Thermal
Measure: DSF
pH: 7.5
Buffer: Hepes 25mM
Ion: NaCl 150mM
Tm: 31.33
dTm: 0.33
Reversibility: Unknown
Reference: The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation. — Rudenko Iakov N|Kaganovich Alice|Hauser David N|Beylina Aleksandra|Chia Ruth|Ding Jinhui|Maric Dragan|Jaffe Howard|Cookson Mark R (Biochem J;446;99-111, 2012)