Protein: Beta-lactamase TEM (Escherichia coli)
UniProt: P62593
EC number: 3.5.2.6
Mutation: A40S|E102K
PDB: 1AXB|1BTL
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: potassium phosphate buffer 200000.0
Tm: 57.6
dTm: 1.18
dG: -7.8
ddG: 0.3
dHvH: -80
Reversibility: yes
State: 2.0
Reference: Enzyme Efficiency but Not Thermostability Drives Cefotaxime Resistance Evolution in TEM-1 ?-Lactamase. — Knies Jennifer L|Cai Fei|Weinreich Daniel M (Mol Biol Evol;34;1040-1054, 2017)