Protein: Transcriptional repressor p66-beta (Homo sapiens)
UniProt: Q8WXI9
Mutation: K450E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0898547825638955
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)