Protein: POU domain, class 3, transcription factor 2 (Homo sapiens)
UniProt: P20265
Mutation: R280D
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.333522397437513
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)