Protein: POU domain, class 2, transcription factor 3 (Homo sapiens)
UniProt: Q9UKI9
Mutation: L253R
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.625828754964834
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)