Protein: E3 ubiquitin-protein ligase RNF113A (Homo sapiens)
UniProt: O15541
EC number: 2.3.2.27
Mutation: H221L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.664623687342896
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)