Protein: POU domain, class 2, transcription factor 1 (Homo sapiens)
UniProt: P14859
Mutation: E289S
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0391603466740845
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)