Protein: POU domain, class 5, transcription factor 1 (Homo sapiens)
UniProt: Q01860
Mutation: L174S
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.831838934491224
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)