Protein: Immunoglobulin heavy constant gamma 1 (Homo sapiens)
UniProt: P01857
Mutation: K253A
PDB: 1FC1|3DJ9|1OQO
Experiment dataset: ProTherm
Method: GdnHCl
Measure: CD
pH: 7.4
Buffer: Sodium phosphate 50 mM
Temperature: 20
dG: 6.9
ddG: 2.2
Cm: 2.83
m-value: 2.45
Reversibility: yes (100%)
Reference: Contribution of domain interface residues to the stability of antibody CH3 domain homodimers. — Dall'Acqua W|Carter P|Mulkerrin M G|Simon A L (Biochemistry;37;9266-73, 1998)