Protein: Cellular retinoic acid-binding protein 1 (Bos taurus)
UniProt: P62964
Mutation: R112Q|R132Q
PDB: 2CBR
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 7
Buffer: potassium phosphate 10 mM
Tm: 68.5
dTm: 14.5
Reversibility: Unknown
Reference: Mutating the charged residues in the binding pocket of cellular retinoic acid-binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability. — Zhang J|Liu Z P|Jones T A|Gierasch L M|Sambrook J F (Proteins;13;87-99, 1992)