Protein: Serine/threonine-protein kinase pim-1 (Homo sapiens)
UniProt: P11309
EC number: 2.7.11.1
Mutation: E135K
PDB: 1XWS
Experiment dataset: ProTherm
Method: Urea
Measure: CD
pH: 7.5
Buffer: Tris-HCl 20mM
Temperature: 10
dG: 1.82
ddG: 4.59
m-value: 0.43
State: 2.0
Reference: Effect of single amino acid substitution observed in cancer on Pim-1 kinase thermodynamic stability and structure. — Consalvi Valerio|Chiaraluce Roberta|Pasquo Alessandra|Lori Clorinda|Lantella Antonella|Alexander Leila T|Knapp Stefan (PLoS One;8;e64824, 2013)