Protein: SH3 and PX domain-containing protein 2B (Homo sapiens)
UniProt: A1X283
Mutation: K253Y
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.202563430662165
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)