Protein: Thioredoxin 1 (Escherichia coli (strain K12))
UniProt: P0AA25
Experiment dataset: ProTherm
Method: GdnHCl
Measure: CD
pH: 6.5
Buffer: ACES 50 mM
Temperature: 25
dG: 10
m-value: 2.4
Reversibility: Unknown
Reference: The conserved, buried aspartic acid in oxidized Escherichia coli thioredoxin has a pKa of 7.5. Its titration produces a related shift in global stability. — Langsetmo K|Woodward C|Fuchs J A (Biochemistry;30;7603-9, 1991)