Protein: Serine/threonine-protein kinase WNK1 (Homo sapiens)
UniProt: Q9H4A3
EC number: 2.7.11.1
Mutation: E491S
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.592913135838528
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)