Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (Homo sapiens)
UniProt: P60484
EC number: 3.1.3.16|3.1.3.48|3.1.3.67
Mutation: F337S
PDB: 1D5R
Experiment dataset: ProTherm
Method: Thermal
Measure: Differential Scanning Fluorimetry
pH: 7.4
Buffer: HEPES 100mM
Ion: NaCl 100mM
Tm: 32.2
dTm: -8.1
Reversibility: Unknown
State: 2.0
Reference: Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders. — Johnston Sean B|Raines Ronald T (Biochemistry;54;1576-82, 2015)