Protein: POU domain, class 4, transcription factor 3 (Homo sapiens)
UniProt: Q15319
Mutation: S222L
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0314010298845439
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)