Protein: Major prion protein (Mus musculus)
UniProt: P04925
Mutation: D177N|M128N
PDB: 1AG2|1XYX
Experiment dataset: ProTherm
Method: Urea
Measure: CD
pH: 7
Buffer: Sodium phosphate 50 mM
Temperature: 25
dG: 5.38
ddG: 1.72
Cm: 4.8
Reversibility: yes
Reference: Influence of amino acid substitutions related to inherited human prion diseases on the thermodynamic stability of the cellular prion protein. — Glockshuber R|Liemann S (Biochemistry;38;3258-67, 1999)