Protein: Tryptophan synthase alpha chain (Escherichia coli (strain K12))
UniProt: P0A877
EC number: 4.2.1.20
Mutation: E49Q
PDB: 1WQ5
Experiment dataset: ProTherm
Method: GdnHCl
Measure: CD
pH: 9
Buffer: Tris-HCl 0.025 M
Temperature: 25
dG: 8.5
ddG: -3.6
Reversibility: yes
Reference: Effect of single amino acid substitutions at the same position on stability of a two-domain protein. — Yutani K|Ogasahara K|Sugino Y|Kimura A (J Mol Biol;160;387-90, 1982)