Protein: Epidermal growth factor receptor kinase substrate 8 (Homo sapiens)
UniProt: Q12929
Mutation: R589I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.0519160552310532
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)