Protein: E3 ubiquitin-protein ligase HECTD1 (Homo sapiens)
UniProt: Q9ULT8
EC number: 2.3.2.26
Mutation: L1917W
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.945691445370252
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)