Protein: Dual specificity mitogen-activated protein kinase kinase 5 (Homo sapiens)
UniProt: Q13163
EC number: 2.7.12.2
Mutation: I21E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.437513350649219
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)