Protein: Tissue-type plasminogen activator (Homo sapiens)
UniProt: P00750
EC number: 3.4.21.68
Mutation: V280M
PDB: 1PML|1TPK
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 4.5
Buffer: Citric acid, trisodium citrate 0.1 M, 0.1 M
Temperature: 64.3
ddG: 2.2
Reversibility: yes
Reference: Effect of residue 65 substitutions on thermal stability of tissue plasminogen activator kringle-2 domain. — Cleary S|Kelley R F (Biochemistry;28;4047-54, 1989)