Protein: Tissue-type plasminogen activator (Homo sapiens)
UniProt: P00750
EC number: 3.4.21.68
Mutation: W277F
PDB: 1PML|1TPK
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 7.4
Buffer: sodium Phosphate 10 mM
Tm: 58.5
dTm: -17.1
dH: 40
Reversibility: Unknown
Reference: Role of tryptophan-63 of the kringle 2 domain of tissue-type plasminogen activator in its thermal stability, folding, and ligand binding properties. — Chang Y|Castellino F J|Zajicek J (Biochemistry;36;7652-63, 1997)