Protein: Proprotein convertase subtilisin/kexin type 9 (Homo sapiens)
UniProt: Q8NBP7
EC number: 3.4.21.-
Mutation: S386A
PDB: 2QTW
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 7.4
Tm: 53.2
dTm: 1.3
Reference: Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor. — Garvie Colin W|Fraley Cara V|Elowe Nadine H|Culyba Elizabeth K|Lemke Christopher T|Hubbard Brian K|Kaushik Virendar K|Daniels Douglas S (Protein Sci;25;2018-2027, 2016)