Protein: POU domain, class 4, transcription factor 1 (Homo sapiens)
UniProt: Q01851
Mutation: I280S
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.138204044755456
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)