Protein: POU domain, class 6, transcription factor 1 (Homo sapiens)
UniProt: Q14863
Mutation: A174E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.12749527694198
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)