Protein: Cellular tumor antigen p53 (Homo sapiens)
UniProt: P04637
Mutation: I332V|M340I|F341L
PDB: 2V5W|1TUP|1SAK
Experiment dataset: ProTherm
Method: GdnHCl
Measure: CD
pH: 7
Buffer: phosphate 25 mM
Temperature: 25
dG: 29.4
ddG: 3.1
Cm: 1.76
m-value: 6.2
Reversibility: Unknown
Reference: Mutually compensatory mutations during evolution of the tetramerization domain of tumor suppressor p53 lead to impaired hetero-oligomerization. — Fersht A R|Mateu M G (Proc Natl Acad Sci U S A;96;3595-9, 1999)