Protein: SAM and SH3 domain-containing protein 1 (Homo sapiens)
UniProt: O94885
Mutation: E649F
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.502143323534282
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)