Protein: Transcriptional coactivator YAP1 (Homo sapiens)
UniProt: P46937
Mutation: I249W
PDB: 1K9Q
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.630212509401527
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)