Protein: Cyclin-dependent kinase inhibitor 2A (Homo sapiens)
UniProt: P42771
Mutation: R124D
PDB: 1A5E
Experiment dataset: ProTherm
Method: Thermal
Measure: CD
pH: 8.5
Buffer: Tris 10 mM
Tm: 45.6
dTm: -0.4
Reversibility: yes
Reference: Design and characterization of a hyperstable p16INK4a that restores Cdk4 binding activity when combined with oncogenic mutations. — Cammett Tobin J|Luo Li|Peng Zheng-yu (J Mol Biol;327;285-97, 2003)