Protein: Urokinase-type plasminogen activator (Homo sapiens)
UniProt: P00749
EC number: 3.4.21.73
Mutation: W50Y
PDB: 1URK
Experiment dataset: ProTherm
Method: Thermal
Measure: DSC
pH: 8
Buffer: Tris-acetate,Sodium acetate, 50 mM,150 mM,
Tm: 58
dTm: -17.6
Reversibility: Unknown
Reference: Role of the strictly conserved tryptophan-25 residue in the stabilization of the structure and in the ligand binding properties of the kringle 2 domain of tissue-type plasminogen activator. — De Serrano V S|Castellino F J (Biochemistry;33;1340-4, 1994)