Protein: Pre-mRNA-processing factor 40 homolog B (Homo sapiens)
UniProt: Q6NWY9
Mutation: E277W
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.641822926502463
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)