Protein: Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (Homo sapiens)
UniProt: Q8WWH4
Mutation: E280I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.747405962267798
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)