Protein: E3 ubiquitin-protein ligase HECW1 (Homo sapiens)
UniProt: Q76N89
EC number: 2.3.2.26
Mutation: D849R
Experiment dataset: Domainome DDG
Domainome ddG: 0.78826835171169
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)