Protein: E3 ubiquitin-protein ligase TTC3 (Homo sapiens)
UniProt: P53804
EC number: 2.3.2.27
Mutation: Y1978R
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.813803327901774
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)