Protein: POU domain, class 2, transcription factor 2 (Homo sapiens)
UniProt: P09086
Mutation: E245D
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.941899439540776
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)