Protein: Tyrosine-protein kinase HCK (Homo sapiens)
UniProt: P08631
EC number: 2.7.10.2
Mutation: E109R
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.372436383564304
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)