Protein: Tyrosine-protein kinase JAK1 (Homo sapiens)
UniProt: P23458
EC number: 2.7.10.2
Mutation: I597F
PDB: 4L00
Experiment dataset: ProTherm
Method: Thermal
Measure: DSF
pH: 8
Buffer: TRIS 20 mM
Ion: MgCl2, NaCl 1mM, 500mM
Tm: 40.3
dTm: -4
Reversibility: Unknown
Reference: Characterization of JAK1 Pseudokinase Domain in Cytokine Signaling. — Raivola Juuli|Haikarainen Teemu|Silvennoinen Olli (Cancers (Basel);12;, 2019)