Protein: POU domain, class 3, transcription factor 2 (Homo sapiens)
UniProt: P20265
Mutation: D290I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.508882560313972
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)