Protein: Cellular tumor antigen p53 (Homo sapiens)
UniProt: P04637
Mutation: F341L|L344F
PDB: 2V5W|1TUP|1SAK
Experiment dataset: ProTherm
Method: GdnHCl
Measure: CD
pH: 7
Buffer: phosphate 25 mM
Temperature: 25
dG: 24.1
ddG: 8.4
Cm: 1.2
m-value: 4.7
Reversibility: Unknown
Reference: Mutually compensatory mutations during evolution of the tetramerization domain of tumor suppressor p53 lead to impaired hetero-oligomerization. — Fersht A R|Mateu M G (Proc Natl Acad Sci U S A;96;3595-9, 1999)