Protein: POU domain, class 3, transcription factor 1 (Homo sapiens)
UniProt: Q03052
Mutation: D253I
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.524050893997251
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)