Protein: E3 ubiquitin-protein ligase MIB1 (Homo sapiens)
UniProt: Q86YT6
EC number: 2.3.2.27
Mutation: I248E
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.18883679832125
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)