Protein: Histone-lysine N-methyltransferase SETD2 (Homo sapiens)
UniProt: Q9BYW2
EC number: 2.1.1.359
Mutation: T2397F
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.25908155204495
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)