Protein: Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens)
UniProt: O43353
EC number: 2.7.11.1
Mutation: E453F
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.515040686771024
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)