Protein: Apoptosis-associated speck-like protein containing a CARD (Homo sapiens)
UniProt: Q9ULZ3
Mutation: D143M
Experiment dataset: Domainome FITNESS
Domainome fitness: -0.263391479441625
Reference: Site-saturation mutagenesis of 500 human protein domains. — Beltran Antoni (Nature;637;885-894, 2025)