LiteFold/DisProt huggingface dataset:
Protein: RAF proto-oncogene serine/threonine-protein kinase
UniProt accession: P04049
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RAF, RAF1
Length: 648 residues
Disorder content (fraction disordered): 0.030864197530864196
Dataset labels: Cancer-related proteins, Autophagy-related proteins, NDDs-related proteins, Condensates-related proteins
Curated region start positions: 236, 238
Curated region end positions: 255, 254
Curated region terms: disorder, disorder
Domain/feature annotations: Transferase(Phosphotransferase) domain 1, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, 3.30.60.20, Phosphorylase Kinase; domain 1, Phorbol esters/diacylglycerol binding domain (C1 domain), Raf-like Ras-binding domain, Protein tyrosine and serine/threonine kinase
Cross-references: PDB:4FJ3, PDB:4IHL
Sequence:
MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLHEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRGQRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLTTSPRLPVF
Protein: DNA fragmentation factor subunit alpha
UniProt accession: O00273
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DFF1, DFF45, DFFA, H13
Length: 331 residues
Disorder content (fraction disordered): 0.3021148036253776
Curated region start positions: 1, 1, 12, 12
Curated region end positions: 100, 100, 100, 100
Curated region terms: disorder, disorder, disorder to order, protein binding
Domain/feature annotations: C-terminal domain of DFF45/ICAD (DFF-C domain), C-terminal domain of DFF45/ICAD (DFF-C domain), 3.10.20.10, CIDE-N domain, DNA Fragmentation factor 45kDa, C terminal domain
Cross-references: PDB:1IBX
Sequence:
MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRSKACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGGTAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQELRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALNWDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQDPT
Protein: Fe(3+)-pyochelin receptor
UniProt accession: P42512
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: PA4221, fptA
Length: 720 residues
Disorder content (fraction disordered): 0.03888888888888889
Curated region start positions: 38, 504
Curated region end positions: 55, 513
Curated region terms: disorder, disorder
Domain/feature annotations: TonB-dependent receptor, beta-barrel domain, TonB-dependent receptor, plug domain, TonB dependent receptor-like, beta-barrel, TonB-dependent Receptor Plug Domain
Cross-references: PDB:1XKW
Sequence:
MKTETKVIKGRQGIARNRHTPLCLGLLLALSPLAAAVADARKDGETELPDMVISGESTSATQPPGVTTLGKVPLKPRELPQSASVIDHERLEQQNLFSLDEAMQQATGVTVQPFQLLTTAYYVRGFKVDSFELDGVPALLGNTASSPQDMAIYERVEILRGSNGLLHGTGNPAATVNLVRKRPQREFAASTTLSAGRWDRYRAEVDVGGPLSASGNVRGRAVAAYEDRDYFYDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITNMAGVPMAKDGSNLGLSRDTYLDVDWDRFKWDTYRAFGSLEQQLGGGWKGKVSAEYQEADSRLRYAGSFGAIDPQTGDGGQLMGAAYKFKSIQRSLDANLNGPVRLFGLTHELLGGVTYAQGETRQDTARFLNLPNTPVNVYRWDPHGVPRPQIGQYTSPGTTTTTQKGLYALGRIKLAEPLTLVVGGRESWWDQDTPATRFKPGRQFTPYGGLIWDFARDWSWYVSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRIDLENNPQEDPDHPGPPNNPFYISGGKVRSQGFELEGTGYLTPYWSLSAGYTYTSTEYLKDSQNDSGTRYSTFTPRHLLRLWSNYDLPWQDRRWSVGGGLQAQSDYSVDYRGVSMRQGGYALVNMRLGYKIDEHWTAAVNVNNLFDRTYYQSLSNPNWNNRYGEPRSFNVSLRGAF
Protein: Protease A inhibitor 3
UniProt accession: P01094
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: PAI3, YM8010.04C, YMR174C
Length: 68 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 2, 33, 2, 2, 1, 1, 1, 2
Curated region end positions: 68, 34, 68, 32, 32, 68, 68, 68, 34
Curated region terms: disorder, disorder, disorder, disorder to order, protein binding, disorder, disorder, protein binding, endopeptidase inhibitor activity
Domain/feature annotations: Saccharopepsin inhibitor I34
Cross-references: BMRB:6078, PDB:1DP5, PDB:1DPJ
Sequence:
MNTDQQKVSEIFQSSKEKLQGDAKVVSDAFKKMASQDKDGKTTDADESEKHNYQEQYNKLKGAGHKKE
Protein: Salt-mediated killer protoxin 1
UniProt accession: P19972
Organism: Millerozyma farinosa
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Debaryomycetaceae, Millerozyma
Gene names: SMK1
Length: 222 residues
Disorder content (fraction disordered): 0.34684684684684686
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 146, 146, 146, 146
Curated region end positions: 222, 222, 222, 222
Curated region terms: disorder, disorder to order, protein binding, toxin sequestering activity
Domain/feature annotations: Smk Toxin, beta chain, Smk Toxin, alpha chain, Salt-mediated killer protoxin 1, beta subunit, SMK1 alpha subunit
Sequence:
MRKETLIGLAFITANVIAWSLRWRMQKSTTIAAIAGCSGAATFGGLAGGIVGCIAAGILAILQGFEVNWHNGGGGDRSNPVKRSSDSFSIVNHNGEKVDSYAHLVPGKVGKVIIDNIELSAIRYANNHTSLGYHFTSDGSGPAARGEATTIWGVGADEAIDKGTPSKNDLQNMSADLAKNGFKGHQGVACSTVKDGNKDVYMIKFSLAGGSNDPGGSPCSDD
Protein: Major capsid protein VP1
UniProt accession: P03087
Organism: Simian virus 40
Taxonomy: Viruses, Monodnaviria, Shotokuvirae, Cossaviricota, Papovaviricetes, Sepolyvirales, Polyomaviridae, Betapolyomavirus
Length: 362 residues
Disorder content (fraction disordered): 0.11049723756906076
Dataset labels: Viral proteins
Curated region start positions: 1, 344, 1, 1
Curated region end positions: 13, 362, 21, 21
Curated region terms: disorder, disorder, disorder, molecular adaptor activity
Domain/feature annotations: Capsid protein VP1,Polyomavirus, Polyomavirus coat protein
Cross-references: PDB:1SVA
Sequence:
MAPTKRKGSCPGAAPKKPKEPVQVPKLVIKGGIEVLGVKTGVDSFTEVECFLNPQMGNPDEHQKGLSKSLAAEKQFTDDSPDKEQLPCYSVARIPLPNINEDLTCGNILMWEAVTVKTEVIGVTAMLNLHSGTQKTHENGAGKPIQGSNFHFFAVGGEPLELQGVLANYRTKYPAQTVTPKNATVDSQQMNTDHKAVLDKDNAYPVECWVPDPSKNENTRYFGTYTGGENVPPVLHITNTATTVLLDEQGVGPLCKADSLYVSAVDICGLFTNTSGTQQWKGLPRYFKITLRKRSVKNPYPISFLLSDLINRRTQRVDGQPMIGMSSQVEEVRVYEDTEELPGDPDMIRYIDEFGQTTTRMQ
Protein: Vitamin D3 receptor
UniProt accession: P11473
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NR1I1, VDR
Length: 427 residues
Disorder content (fraction disordered): 0.11943793911007024
Dataset labels: NDDs-related proteins
Curated region start positions: 165
Curated region end positions: 215
Curated region terms: disorder
Domain/feature annotations: Retinoid X Receptor, Erythroid Transcription Factor GATA-1, subunit A, Ligand-binding domain of nuclear hormone receptor, Double treble clef zinc finger, C4 type
Sequence:
MEAMAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRVNDGGGSHPSRPNSRHTPSFSGDSSSSCSDHCITSSDMMDSSSFSNLDLSEEDSDDPSVTLELSQLSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDDMSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPECSMKLTPLVLEVFGNEIS
Protein: Late embryogenesis abundant protein 1
UniProt accession: Q95V77
Organism: Aphelenchus avenae
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Nematoda, Chromadorea, Rhabditida, Tylenchina, Tylenchomorpha, Aphelenchoidea, Aphelenchidae, Aphelenchus
Length: 143 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 143, 143, 143, 143
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: Apolipoprotein
Sequence:
MSSQQNQNRQGEQQEQGYMEAAKEKVVNAWESTKETLSSTAQAAAEKTAEFRDSAGETIRDLTGQAQEKGQEFKERAGEKAEETKQRAGEKMDETKQRAGEMRENAGQKMEEYKQQGKGKAEELRDTAAEKLHQAGEKVKGRD
Protein: Major prion protein
UniProt accession: P04273
Organism: Mesocricetus auratus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Cricetidae, Cricetinae, Mesocricetus
Gene names: PRNP, PRP
Length: 254 residues
Disorder content (fraction disordered): 0.4094488188976378
Dataset labels: Condensates-related proteins
Curated region start positions: 23, 90, 90, 23, 23, 23, 23, 23
Curated region end positions: 106, 126, 122, 106, 106, 106, 106, 106
Curated region terms: disorder, disorder, disorder, disorder, disorder to order, amyloid fibril formation, amyloid fibril formation, disorder to order
Domain/feature annotations: Prion/Doppel protein, beta-ribbon domain, Prion/Doppel alpha-helical domain, Copper binding octapeptide repeat region, Major prion protein bPrPp - N terminal
Cross-references: PDB:1B10, PDB:2KKG, PDB:4YXL
Sequence:
MANLSYWLLALFVAMWTDVGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGTWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHNQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPMMHFGNDWEDRYYRENMNRYPNQVYYRPVDQYNNQNNFVHDCVNITIKQHTVTTTTKGENFTETDIKIMERVVEQMCTTQYQKESQAYYDGRRSSAVLFSSPPVILLISFLIFLMVG
Protein: Oxygen-evolving enhancer protein 1, chloroplastic
UniProt accession: P12359
Organism: Spinacia oleracea
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, Caryophyllales, Chenopodiaceae, Chenopodioideae, Anserineae, Spinacia
Gene names: PSBO
Length: 332 residues
Disorder content (fraction disordered): 0.26506024096385544
Curated region start positions: 1
Curated region end positions: 88
Curated region terms: disorder
Domain/feature annotations: Photosystem II, cytochrome c-550 precursor, photosynthetic oxygen evolving center domain, Manganese-stabilising protein / photosystem II polypeptide
Cross-references: EMDB:6617, PDB:3JCU
Sequence:
MAASLQASTTFLQPTKVASRNTLQLRSTQNVCKAFGVESASSGGRLSLSLQSDLKELANKCVDATKLAGLALATSALIASGANAEGGKRLTYDEIQSKTYLEVKGTGTANQCPTVEGGVDSFAFKPGKYTAKKFCLEPTKFAVKAEGISKNSGPDFQNTKLMTRLTYTLDEIEGPFEVSSDGTVKFEEKDGIDYAAVTVQLPGGERVPFLFTIKQLVASGKPESFSGDFLVPSYRGSSFLDPKGRGGSTGYDNAVALPAGGRGDEEELQKENNKNVASSKGTITLSVTSSKPETGEVIGVFQSLQPSDTDLGAKVPKDVKIEGVWYAQLEQQ
Protein: Protein Nef
UniProt accession: P04324
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate PCV12)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 206 residues
Disorder content (fraction disordered): 0.23786407766990292
Dataset labels: Viral proteins
Curated region start positions: 42, 2, 2, 2, 2
Curated region end positions: 57, 14, 34, 14, 14
Curated region terms: disorder, disorder, disorder, disorder to order, fatty acylation display site
Domain/feature annotations: HIV 1 nef anchor domain, Nef Regulatory Factor, Negative factor, (F-Protein) or Nef
Cross-references: PDB:1QA4, PDB:1QA5
Sequence:
MGGKWSKSSVVGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: Sulfite reductase [NADPH] flavoprotein alpha-component
UniProt accession: P38038
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW2734, b2764, cysJ
Length: 599 residues
Disorder content (fraction disordered): 0.035058430717863104
Curated region start positions: 52, 209
Curated region end positions: 62, 218
Curated region terms: disorder, disorder
Domain/feature annotations: Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module, NADPH-cytochrome p450 Reductase; Chain A, domain 3, 3.40.50.360, Translation factors, Oxidoreductase NAD-binding domain, Flavodoxin, FAD binding domain
Cross-references: PDB:1YKG
Sequence:
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGMRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKDGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
Protein: Kappa-casein
UniProt accession: P02668
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: CSN10, CSN3, CSNK
Length: 190 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1
Curated region end positions: 190
Curated region terms: disorder
Domain/feature annotations: Kappa casein
Sequence:
MMKSFFLVVTILALTLPFLGAQEQNQEQPIRCEKDERFFSDKIAKYIPIQYVLSRYPSYGLNYYQQKPVALINNQFLPYPYYAKPAAVRSPAQILQWQVLSNTVPAKSCQAQPTTMARHPHPHLSFMAIPPKKNQDKTEIPTINTIASGEPTSTPTTEAVESTVATLEDSPEVIESPPEINTVQVTSTAV
Protein: Non-histone chromosomal protein HMG-17
UniProt accession: P02313
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: HMG17, HMGN2
Length: 90 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 16, 1
Curated region end positions: 90, 90, 90, 41, 90
Curated region terms: disorder, disorder, disorder, nucleic acid binding, disorder
Domain/feature annotations: HMG14 and HMG17
Sequence:
MPKRKAEGDAEGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDGNNPAENGDAKTDQAQKAEGAGDAK
Protein: Calpastatin
UniProt accession: P20810
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CAST
Length: 708 residues
Disorder content (fraction disordered): 0.19915254237288135
Curated region start positions: 137, 137, 137, 137, 137
Curated region end positions: 277, 277, 277, 277, 277
Curated region terms: disorder, pre-molten globule, pre-molten globule, limited proteolysis display site, pre-molten globule
Domain/feature annotations: Calpain inhibitor, Calpain inhibitor, Calpain inhibitor, Calpain inhibitor
Sequence:
MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Protein: Translation initiation factor IF-3
UniProt accession: P0A707
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW5829, b1718, fit, infC, srjA
Length: 180 residues
Disorder content (fraction disordered): 0.06666666666666667
Dataset labels: RNA-binding proteins
Curated region start positions: 78, 78
Curated region end positions: 89, 89
Curated region terms: disorder, flexible linker
Domain/feature annotations: Translation initiation factor 3 (IF-3), C-terminal domain, Translation initiation factor 3 (IF-3), N-terminal domain, Translation initiation factor IF-3, C-terminal domain, Translation initiation factor IF-3, N-terminal domain
Sequence:
MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
Protein: T-cell surface glycoprotein CD3 zeta chain
UniProt accession: P20963
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CD247, CD3Z, T3Z, TCRZ
Length: 164 residues
Disorder content (fraction disordered): 0.7073170731707317
Curated region start positions: 49, 49, 49, 49, 49
Curated region end positions: 164, 164, 164, 164, 164
Curated region terms: disorder, disorder, protein complex oligomerization, protein complex oligomerization, protein complex oligomerization
Domain/feature annotations: Immunoreceptor tyrosine-based activation motif, Immunoreceptor tyrosine-based activation motif, T-cell surface glycoprotein CD3 zeta chain
Sequence:
MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPQRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR
Protein: ATP synthase-coupling factor 6, mitochondrial
UniProt accession: P02721
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: ATP5J, ATP5PF
Length: 108 residues
Disorder content (fraction disordered): 0.3425925925925926
Curated region start positions: 55, 84
Curated region end positions: 66, 108
Curated region terms: disorder, disorder
Domain/feature annotations: Mitochondrial ATP synthase-coupling factor 6, Mitochondrial ATP synthase coupling factor 6
Cross-references: PDB:1VZS
Sequence:
MILQRLFRLSSAVQSAISVSWRRNIGITAVAFNKELDPVQKLFVDKIREYRTKRQTSGGPVDAGPEYQQDLDRELFKLKQMYGKADMNTFPNFTFEDPKFEVVEKPQS
Protein: DNA gyrase inhibitor YacG
UniProt accession: P0A8H9
Organism: Escherichia coli O157:H7
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: ECs0105, Z0111, yacG
Length: 65 residues
Disorder content (fraction disordered): 0.4
Curated region start positions: 40
Curated region end positions: 65
Curated region terms: disorder
Domain/feature annotations: Erythroid Transcription Factor GATA-1, subunit A, DNA gyrase inhibitor YacG
Cross-references: DisProt:DP01714r002, PDB:1LV3
Sequence:
MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEEKRIPSSGDLSESDDWSEEPKQ
Protein: Ribonuclease E
UniProt accession: P21513
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1071, ams, b1084, hmp1, rne
Length: 1061 residues
Disorder content (fraction disordered): 0.5315739868049011
Dataset labels: RNA-binding proteins
Curated region start positions: 498, 628, 498, 603, 603, 816, 816, 816, 498, 498, 498, 628, 628, 628, 628, 628, 580, 816, 833, 1021
Curated region end positions: 1061, 843, 1061, 850, 850, 850, 850, 850, 1061, 1061, 1061, 843, 843, 843, 843, 843, 1038, 1038, 850, 1061
Curated region terms: disorder, disorder, disorder, disorder, disorder, protein binding, disorder to molten globule, molecular adaptor activity, disorder, protein binding, protein complex oligomerization, 7S RNA binding, protein binding, positive regulation of ATP-dependent activity, protein binding, disorder, disorder, protein binding, protein binding, protein binding
Domain/feature annotations: Nucleic acid-binding proteins, Ribonuclease E, catalytic domain, S1 RNA binding domain, Ribonuclease E/G family, Polyribonucleotide phosphorylase C terminal, RNase E/G, Thioredoxin-like domain
Cross-references: PDB:5OHG
Sequence:
MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKGKITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIVQIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLELPEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAFRDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIESAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQLRLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRLSPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASYLLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEEAMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPAAPAQPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRSRRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQVEEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTHPEVIAAAVTEQPQVITESDVAVAQEVAEQAEPVVEPQEETADIEEVVETAEVVVAEPEVVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQRPTFAFEGKGAAGGHTATHHASAAPARPQPVE
Protein: Osteopontin
UniProt accession: P10451
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BNSP, OPN, PSEC0156, SPP1
Length: 314 residues
Disorder content (fraction disordered): 1
Dataset labels: Extracellular matrix proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 158, 1, 17, 17, 17, 17, 85, 85, 1
Curated region end positions: 314, 314, 314, 314, 314, 314, 314, 162, 314, 314, 314, 314, 314, 116, 116, 314
Curated region terms: disorder, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, calcium ion binding, disorder, phosphorylation display site, phosphorylation display site, disorder, calcium ion binding, small molecule binding, molecular adaptor activity
Domain/feature annotations: Osteopontin
Cross-references: BMRB:19999, BMRB:50447
Sequence:
MRIAVICFCLLGITCAIPVKQADSGSSEEKQLYNKYPDAVATWLNPDPSQKQNLLAPQNAVSSEETNDFKQETLPSKSNESHDHMDDMDDEDDDDHVDSQDSIDSNDSDDVDDTDDSHQSDESHHSDESDELVTDFPTDLPATEVFTPVVPTVDTYDGRGDSVVYGLRSKSKKFRRPDIQYPDATDEDITSHMESEELNGAYKAIPVAQDLNAPSDWDSRGKDSYETSQLDDQSAETHSHKQSRLYKRKANDESNEHSDVIDSQELSKVSREFHSHEFHSHEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN
Protein: Nucleoplasmin
UniProt accession: P05221
Organism: Xenopus laevis
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Amphibia, Batrachia, Anura, Pipoidea, Pipidae, Xenopodinae, Xenopus, Xenopus
Length: 200 residues
Disorder content (fraction disordered): 0.455
Curated region start positions: 153, 120, 1, 125
Curated region end positions: 171, 200, 10, 200
Curated region terms: importin-alpha family protein binding, disorder, disorder, disorder
Domain/feature annotations: Nucleoplasmin core domain, Nucleoplasmin/nucleophosmin domain
Cross-references: PDB:1EE5
Sequence:
MASTVSNTSKLEKPVSLIWGCELNEQDKTFEFKVEDDEEKCEHQLALRTVCLGDKAKDEFNIVEIVTQEEGAEKSVPIATLKPSILPMATMVGIELTPPVTFRLKAGSGPLYISGQHVAMEEDYSWAEEEDEGEAEGEEEEEEEEDQESPPKAVKRPAATKKAGQAKKKKLDKEDESSEEDSPTKKGKGAGRGRKPAAKK