LiteFold/DisProt huggingface dataset:
Protein: Ubiquitin carboxyl-terminal hydrolase 7
UniProt accession: Q93009
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HAUSP, USP7
Length: 1102 residues
Disorder content (fraction disordered): 0.05807622504537205
Dataset labels: NDDs-related proteins
Curated region start positions: 54, 174, 105, 174, 500, 1084
Curated region end positions: 64, 187, 114, 187, 509, 1102
Curated region terms: disorder, disorder, disorder, disorder to order, disorder, disorder
Domain/feature annotations: Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A, Cysteine proteinases, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, Ubiquitin carboxyl-terminal hydrolase, ICP0-binding domain of Ubiquitin-specific protease 7, Ubiquitin-specific protease C-terminal, MATH domain
Cross-references: PDB:1YY6, PDB:1YZE, PDB:2F1Z, PDB:5C56
Sequence:
MNHQQQQQQQKAGEQQLSEPEDMEMEAGDTDDPPRITQNPVINGNVALSDGHNTAEEDMEDDTSWRSEATFQFTVERFSRLSESVLSPPCFVRNLPWKIMVMPRFYPDRPHQKSVGFFLQCNAESDSTSWSCHAQAVLKIINYRDDEKSFSRRISHLFFHKENDWGFSNFMAWSEVTDPEKGFIDDDKVTFEVFVQADAPHGVAWDSKKHTGYVGLKNQGATCYMNSLLQTLFFTNQLRKAVYMMPTEGDDSSKSVPLALQRVFYELQHSDKPVGTKKLTKSFGWETLDSFMQHDVQELCRVLLDNVENKMKGTCVEGTIPKLFRGKMVSYIQCKEVDYRSDRREDYYDIQLSIKGKKNIFESFVDYVAVEQLDGDNKYDAGEHGLQEAEKGVKFLTLPPVLHLQLMRFMYDPQTDQNIKINDRFEFPEQLPLDEFLQKTDPKDPANYILHAVLVHSGDNHGGHYVVYLNPKGDGKWCKFDDDVVSRCTKEEAIEHNYGGHDDDLSVRHCTNAYMLVYIRESKLSEVLQAVTDHDIPQQLVERLQEEKRIEAQKRKERQEAHLYMQVQIVAEDQFCGHQGNDMYDEEKVKYTVFKVLKNSSLAEFVQSLSQTMGFPQDQIRLWPMQARSNGTKRPAMLDNEADGNKTMIELSDNENPWTIFLETVDPELAASGATLPKFDKDHDVMLFLKMYDPKTRSLNYCGHIYTPISCKIRDLLPVMCDRAGFIQDTSLILYEEVKPNLTERIQDYDVSLDKALDELMDGDIIVFQKDDPENDNSELPTAKEYFRDLYHRVDVIFCDKTIPNDPGFVVTLSNRMNYFQVAKTVAQRLNTDPMLLQFFKSQGYRDGPGNPLRHNYEGTLRDLLQFFKPRQPKKLYYQQLKMKITDFENRRSFKCIWLNSQFREEEITLYPDKHGCVRDLLEECKKAVELGEKASGKLRLLEIVSYKIIGVHQEDELLECLSPATSRTFRIEEIPLDQVDIDKENEMLVTVAHFHKEVFGTFGIPFLLRIHQGEHFREVMKRIQSLLDIQEKEFEKFKFAIVMMGRHQYINEDEYEVNLKDFEPQPGNMSHPRPWLGLDHFNKAPKRSRYTYLEKAIKIHN
Protein: Conglutin
UniProt accession: Q647G9
Organism: Arachis hypogaea
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, fabids, Fabales, Fabaceae, Papilionoideae, 50 kb inversion clade, dalbergioids sensu lato, Dalbergieae, Pterocarpus clade, Arachis
Length: 145 residues
Disorder content (fraction disordered): 0.3103448275862069
Curated region start positions: 22, 57, 129
Curated region end positions: 34, 71, 145
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Plant lipid-transfer and hydrophobic proteins, Protease inhibitor/seed storage/LTP family
Cross-references: PDB:1W2Q
Sequence:
MAKSTILVALLALVLVAHASAMRRERGRQGDSSSCERQVDRVNLKPCEQHIMQRIMGEQEQYDSYDIRSTRSSDQQQRCCDELNEMENTQRCMCEALQQIMENQCDRLQDRQMVQQFKRELMNLPQQCNFRAPQRCDLDVSGGRC
Protein: 50S ribosomal protein L32e
UniProt accession: P12736
Organism: Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Taxonomy: Archaea, Euryarchaeota, Stenosarchaea group, Halobacteria, Halobacteriales, Haloarculaceae, Haloarcula
Gene names: rpl32e, rrnAC1595
Length: 241 residues
Disorder content (fraction disordered): 0.3941908713692946
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 95, 95, 95, 95
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: 5' to 3' exonuclease, C-terminal subdomain, Ribosomal protein L32, Helix-hairpin-helix domain
Cross-references: PDB:1JJ2, PDB:1K8A, PDB:1K9M, PDB:1KD1, PDB:1KQS, PDB:1M1K, PDB:1Q82
Sequence:
MADNEEDVEAEEEYTELTDISGVGPSKAESLREAGFESVEDVRGADQSALADVSGIGNALAARIKADVGGLEVESETEAEVEEEGGEEAPDEDVETELQARGLTEKTPDLSDEDARLLTQRHRVGKPQFNRQDHHKKKRVSTSWRKPRGQLSKQRRGIKGKGDTVEAGFRSPTAVRGKHPSGFEEVRVHNVDDLEGVDGDTEAVRIASKVGARKRERIEEEAEDAGIRVLNPTYVEVEVSE
Protein: Nucleoprotein
UniProt accession: P59595
Organism: Human SARS coronavirus
Taxonomy: Viruses, Riboviria, Orthornavirae, Pisuviricota, Pisoniviricetes, Nidovirales, Cornidovirineae, Coronaviridae, Orthocoronavirinae, Betacoronavirus, Sarbecovirus
Gene names: 9a, N
Length: 422 residues
Disorder content (fraction disordered): 0.42890995260663506
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 1, 182, 366, 182, 182, 248, 248, 248, 182, 184, 182, 1, 182, 366, 1, 366
Curated region end positions: 44, 247, 422, 247, 247, 259, 259, 259, 247, 196, 247, 44, 247, 422, 46, 382
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, molecular adaptor activity, DNA binding, flexible linker, self-assembly, disorder, RNA binding, RNA binding, RNA binding, disorder, single-stranded DNA binding
Domain/feature annotations: Coronavirus nucleocapsid
Cross-references: PDB:2JW8
Sequence:
MSDNGPQSNQRSAPRITFGGPTDSTDNNQNGGRNGARPKQRRPQGLPNNTASWFTALTQHGKEELRFPRGQGVPINTNSGPDDQIGYYRRATRRVRGGDGKMKELSPRWYFYYLGTGPEASLPYGANKEGIVWVATEGALNTPKDHIGTRNPNNNAATVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRGNSRNSTPGSSRGNSPARMASGGGETALALLLLDRLNQLESKVSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKQYNVTQAFGRRGPEQTQGNFGDQDLIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYHGAIKLDDKDPQFKDNVILLNKHIDAYKTFPPTEPKKDKKKKTDEAQPLPQRQKKQPTVTLLPAADMDDFSRQLQNSMSGASADSTQA
Protein: Regulator of nonsense transcripts 2
UniProt accession: Q9HAU5
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIAA1408, RENT2, UPF2
Length: 1272 residues
Disorder content (fraction disordered): 0.23977987421383648
Dataset labels: NDDs-related proteins, RNA-binding proteins
Curated region start positions: 1105, 1105, 1105, 1167, 1167, 1167, 1130, 1130, 430, 481, 1025, 757, 757, 1042, 1207, 1167, 1171, 1171, 1015, 1105, 1167, 1108, 1105
Curated region end positions: 1129, 1129, 1129, 1207, 1207, 1207, 1166, 1166, 486, 536, 1078, 767, 767, 1050, 1227, 1207, 1176, 1176, 1054, 1207, 1207, 1128, 1129
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder to order, protein binding, disorder, flexible linker, disorder, disorder, disorder, disorder, flexible linker, phosphorylation display site, disorder, protein binding, protein binding, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, disorder, disorder, protein binding, protein binding, protein binding
Domain/feature annotations: 1.25.40.180, 1.25.40.180, 1.25.40.180, MIF4G domain, MIF4G domain, MIF4G domain, Up-frameshift suppressor 2
Cross-references: PDB:2WJV, PDB:4CEK, PDB:4CEM, PDB:7QG6
Sequence:
MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR
Protein: Neuromodulin
UniProt accession: P17677
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GAP43
Length: 238 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 238, 238, 238, 238
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: 1.20.5.190, IQ calmodulin-binding motif, Neuromodulin, Gap junction protein N-terminal region
Cross-references: BMRB:19246
Sequence:
MLCCMRRTKQVEKNDDDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKDDVQAAEAEANKKDEAPVADGVEKKGEGTTTAEAAPATGSKPDEPGKAGETPSEEKKGEGDAATEQAAPQAPASSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATTPAAEDAAAKATAQPPTETGESSQAEENIEAVDETKPKESARQDEGKEEEPEADQEHA
Protein: Ubiquitin-conjugating enzyme E2 Z
UniProt accession: Q9H832
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HOYS7, UBE2Z
Length: 354 residues
Disorder content (fraction disordered): 0.3587570621468927
Curated region start positions: 1, 1, 327
Curated region end positions: 99, 99, 354
Curated region terms: disorder, molecular adaptor activity, disorder
Domain/feature annotations: Ubiquitin Conjugating Enzyme, Ubiquitin-conjugating enzyme
Cross-references: PDB:5A4P
Sequence:
MAESPTEEAATAGAGAAGPGASSVAGVVGVSGSGGGFGPPFLPDVWAAAAAAGGAGGPGSGLAPLPGLPPSAAAHGAALLSHWDPTLSSDWDGERTAPQCLLRIKRDIMSIYKEPPPGMFVVPDTVDMTKIHALITGPFDTPYEGGFFLFVFRCPPDYPIHPPRVKLMTTGNNTVRFNPNFYRNGKVCLSILGTWTGPAWSPAQSISSVLISIQSLMTENPYHNEPGFEQERHPGDSKNYNECIRHETIRVAVCDMMEGKCPCPEPLRGVMEKSFLEYYDFYEVACKDRLHLQGQTMQDPFGEKRGHFDYQSLLMRLGLIRQKVLERLHNENAEMDSDSSSSGTETDLHGSLRV
Protein: Axin-1
UniProt accession: Q9YGY0
Organism: Xenopus laevis
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Amphibia, Batrachia, Anura, Pipoidea, Pipidae, Xenopodinae, Xenopus, Xenopus
Gene names: axin, axin1, axn
Length: 842 residues
Disorder content (fraction disordered): 0.06294536817102138
Curated region start positions: 435, 435, 483
Curated region end positions: 465, 465, 504
Curated region terms: disorder, flexible linker, disorder
Domain/feature annotations: 3.10.20.380, 1.10.196.10, 1.10.196.10, Regulator of G-protein Signalling 4, domain 2, Regulator of G protein signaling domain, DIX domain, Axin beta-catenin binding motif, Axin-1 tankyrase binding domain
Cross-references: PDB:1QZ7
Sequence:
MSVKGKGFPLDLGGSFTEDAPRPPVPGEEGELITTDQRPFSHTYYSLKNDGIKNETSTATPRRPDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGIHLFRTFLQQENCADLLDFWFACSGFRKLEPNDSKVEKRLKLAKAIYKKYVLDSNGIVSRQIKPATKSFIKDCVLRQQIDPAMFDQAQMEIQSMMEDNTYPVFLKSDIYLEYTTIGGESPKNYSDQSSGSGTGKGPSGYLPTLNEDEEWRCDQGGEHERERECIPSSLFSQKLALDSSSHCAGSNRRLSDGREFRPGTWREPVNPYYVNTGYAGAPVTSANDSEQQSMSSDADTMSLTDSSVDGIPPYRLRKHYRREMQESANANGRGPLPHIPRTYHMPKDIHVDPEKFAAELISRLEGVLRDREAEQKLEERLKRVRAEEEGDDGDVSSGPSVISHKLPSGPPMHHFNSRYSETGCVGMQIRDAHEENPESILDEHVQRVMKTPGCQSPGTGRHSPKSRSPDGHLSKTLPGSLGTMQTGHGKHSSKSTAKVDSGNLHHHKHVYHHVHHHGGVKPKEQIDGESTQRVQTNFPWNVESHNYATKSRNYAESMGMAPNPMDSLAYSGKVSMLSKRNAKKADLGKSESASHEMPVVPEDSERHQKILQWIMEGEKEIIRHKKSNHSSSSAKKQPPTELARPLSIERPGAVHPWVSAQLRNVVQPSHPFIQDPTMPPNPAPNPLTQLVSKPGARLEEEEKKAAKMPQKQRLKPQKKNVSAPSQPCDNIVVAYYFCGEPIPYRTMVKGRVVTLGQFKELLTKKGNYRYYFKKVSDEFDCGVVFEEVREDDMILPIYEEKIIGQVEKID
Protein: Neuromodulin
UniProt accession: P06836
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: GAP43
Length: 242 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 38, 38, 1, 1
Curated region end positions: 242, 242, 51, 51, 242, 242
Curated region terms: disorder, disorder, protein binding, disorder to order, localization, lipid binding
Domain/feature annotations: 1.20.5.190, IQ calmodulin-binding motif, Neuromodulin, Gap junction protein N-terminal region
Sequence:
MLCCMRRTKQVEKNDEDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAPAAEAEANEKDEAAVAEGTEKKEGEGSTPAEAAPGAGPKPEEKTGKAGETPSEEKKGEGAPDAATEQAAPQAPAPSEEKAGSAETESATKASTDNSPSSKAEDAPAKEEPKQADVPAAVTAAAATAPAAEDAAAMATAQPPTETAESSQAEEKIEAVDETKPKDSARQDEGKGEEREADQEHA
Protein: SBDS-like protein
UniProt accession: C0J347
Organism: Trypanosoma cruzi
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Trypanosoma, Schizotrypanum
Length: 464 residues
Disorder content (fraction disordered): 0.4331896551724138
Dataset labels: Neglected tropical diseases proteins, RNA-binding proteins
Curated region start positions: 264, 264, 264, 264, 264
Curated region end positions: 464, 464, 464, 464, 464
Curated region terms: disorder, disorder to order, disorder, disorder, RNA binding
Domain/feature annotations: SBDS protein C-terminal domain, subdomain 1, Ribosome maturation protein SBDS, N-terminal domain, Shwachman-Bodian-Diamond syndrome (SBDS) N-terminal domain, SBDS protein, domain II
Sequence:
MSARIQVPLSQRRHTNVAVVRYTKNGVRLEIACYKNKVISYRGGIETRMDEVLQVERVFTNVSRGLYSSEKEIEAVFGKGTSEKEALQYILDHGELQVAQQERAAEIDQMFIDIAVIISQKCVNEVTQRPFPSQVIEQALHSIGAAVKLDQPVKKQALAFIHQLIDAKTIPIARARMKLRCVVPDEPSLEKLVEWCETNGTSILQKVVEAGGSDAALQIHSLLILLQPHLFRDIERFVKTEMPPGGSVHVIENAAMDVGEGDVMDAELIARANAHMTGASGVGNADKSHCTGSSSNPHAESNRGRRKGKGGSRKPQGVQRVLGKDDGTDQQTVTTAELSSTPAVVGENDDELKVALSKLVLDETNGSRDEDYDGKGRRGKKKAKRRQGEPHQKQQQQPATPQKTVEVDEQQGSDEEVLVNRKQRKQAAARVRVKDDKRNEYWNDADDDDYDYGYEDEDAGEVRD
Protein: EKC/KEOPS complex subunit GON7
UniProt accession: P46984
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: GON7, J0420, LDB6, PCC2, YJL184W
Length: 123 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 2, 2, 2, 2, 65, 65, 65, 65
Curated region end positions: 123, 21, 21, 21, 21, 113, 113, 113, 113
Curated region terms: disorder, disorder, molecular adaptor activity, disorder to order, protein binding, disorder, molecular adaptor activity, disorder to order, protein binding
Domain/feature annotations: Gon7 family
Cross-references: PDB:4WXA
Sequence:
MKLPVAQYSAPDGVEKSFAPIRDDPRYMTTEGRTTGPSDHVLNAGQIDRDKPSEPERTKDGSQLTYLGQLRTQLTGLQDDINEFLTGRMELAKNKKKAGADEKRIQEEINQLLDGGDGDEDAV
Protein: Axin-1
UniProt accession: O15169
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AXIN, AXIN1
Length: 862 residues
Disorder content (fraction disordered): 0.23897911832946636
Dataset labels: Cancer-related proteins, Condensates-related proteins
Curated region start positions: 295, 295, 295, 295, 295, 295, 295
Curated region end positions: 500, 500, 500, 500, 500, 500, 500
Curated region terms: disorder, disorder, disorder, disorder, molecular adaptor activity, beta-catenin binding, protein binding
Domain/feature annotations: 3.10.20.380, 1.10.196.10, 1.10.196.10, Regulator of G-protein Signalling 4, domain 2, Regulator of G protein signaling domain, DIX domain, Axin beta-catenin binding motif, Axin-1 tankyrase binding domain
Sequence:
MNIQEQGFPLDLGASFTEDAPRPPVPGEEGELVSTDPRPASYSFCSGKGVGIKGETSTATPRRSDLDLGYEPEGSASPTPPYLKWAESLHSLLDDQDGISLFRTFLKQEGCADLLDFWFACTGFRKLEPCDSNEEKRLKLARAIYRKYILDNNGIVSRQTKPATKSFIKGCIMKQLIDPAMFDQAQTEIQATMEENTYPSFLKSDIYLEYTRTGSESPKVCSDQSSGSGTGKGISGYLPTLNEDEEWKCDQDMDEDDGRDAAPPGRLPQKLLLETAAPRVSSSRRYSEGREFRYGSWREPVNPYYVNAGYALAPATSANDSEQQSLSSDADTLSLTDSSVDGIPPYRIRKQHRREMQESVQVNGRVPLPHIPRTYRVPKEVRVEPQKFAEELIHRLEAVQRTREAEEKLEERLKRVRMEEEGEDGDPSSGPPGPCHKLPPAPAWHHFPPRCVDMGCAGLRDAHEENPESILDEHVQRVLRTPGRQSPGPGHRSPDSGHVAKMPVALGGAASGHGKHVPKSGAKLDAAGLHHHRHVHHHVHHSTARPKEQVEAEATRRAQSSFAWGLEPHSHGARSRGYSESVGAAPNASDGLAHSGKVGVACKRNAKKAESGKSASTEVPGASEDAEKNQKIMQWIIEGEKEISRHRRTGHGSSGTRKPQPHENSRPLSLEHPWAGPQLRTSVQPSHLFIQDPTMPPHPAPNPLTQLEEARRRLEEEEKRASRAPSKQRYVQEVMRRGRACVRPACAPVLHVVPAVSDMELSETETRSQRKVGGGSAQPCDSIVVAYYFCGEPIPYRTLVRGRAVTLGQFKELLTKKGSYRYYFKKVSDEFDCGVVFEEVREDEAVLPVFEEKIIGKVEKVD
Protein: Signal transducer and activator of transcription 2
UniProt accession: P52630
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: STAT2
Length: 851 residues
Disorder content (fraction disordered): 0.06227967097532315
Curated region start positions: 786, 786, 786, 817, 817
Curated region end positions: 816, 816, 816, 838, 838
Curated region terms: disorder, disorder to order, protein binding, disorder, protein binding
Domain/feature annotations: STAT transcription factor, N-terminal domain, STAT transcription factor, DNA-binding domain, SH2 domain, EF-hand, STAT transcription factor, all-alpha domain, SH2 domain, STAT transcription factor, coiled-coil domain, STAT protein, DNA binding domain, STAT protein, protein interaction domain, Signal transducer and activator of transcription 2 C terminal, Signal transducer and activator of transcription, linker domain
Cross-references: BMRB:16014, PDB:2KA4
Sequence:
MAQWEMLQNLDSPFQDQLHQLYSHSLLPVDIRQYLAVWIEDQNWQEAALGSDDSKATMLFFHFLDQLNYECGRCSQDPESLLLQHNLRKFCRDIQPFSQDPTQLAEMIFNLLLEEKRILIQAQRAQLEQGEPVLETPVESQQHEIESRILDLRAMMEKLVKSISQLKDQQDVFCFRYKIQAKGKTPSLDPHQTKEQKILQETLNELDKRRKEVLDASKALLGRLTTLIELLLPKLEEWKAQQQKACIRAPIDHGLEQLETWFTAGAKLLFHLRQLLKELKGLSCLVSYQDDPLTKGVDLRNAQVTELLQRLLHRAFVVETQPCMPQTPHRPLILKTGSKFTVRTRLLVRLQEGNESLTVEVSIDRNPPQLQGFRKFNILTSNQKTLTPEKGQSQGLIWDFGYLTLVEQRSGGSGKGSNKGPLGVTEELHIISFTVKYTYQGLKQELKTDTLPVVIISNMNQLSIAWASVLWFNLLSPNLQNQQFFSNPPKAPWSLLGPALSWQFSSYVGRGLNSDQLSMLRNKLFGQNCRTEDPLLSWADFTKRESPPGKLPFWTWLDKILELVHDHLKDLWNDGRIMGFVSRSQERRLLKKTMSGTFLLRFSESSEGGITCSWVEHQDDDKVLIYSVQPYTKEVLQSLPLTEIIRHYQLLTEENIPENPLRFLYPRIPRDEAFGCYYQEKVNLQERRKYLKHRLIVVSNRQVDELQQPLELKPEPELESLELELGLVPEPELSLDLEPLLKAGLDLGPELESVLESTLEPVIEPTLCMVSQTVPEPDQGPVSQPVPEPDLPCDLRHLNTEPMEIFRNCVKIEEIMPNGDPLLAGQNTVDEVYVSRPSHFYTDGPLMPSDF
Protein: Signal transducer and activator of transcription 1-alpha/beta
UniProt accession: P42224
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: STAT1
Length: 750 residues
Disorder content (fraction disordered): 0.05466666666666667
Curated region start positions: 710, 720, 720, 720
Curated region end positions: 719, 750, 750, 750
Curated region terms: disorder, disorder, disorder to order, protein binding
Domain/feature annotations: STAT transcription factor, N-terminal domain, SH2 domain, STAT transcription factor, DNA-binding domain, signal transducer and activator of transcription 1, EF-hand, STAT transcription factor, all-alpha domain, SH2 domain, STAT transcription factor, coiled-coil domain, STAT protein, DNA binding domain, STAT protein, protein interaction domain, STAT1 TAZ2 binding domain, Signal transducer and activator of transcription, linker domain
Cross-references: BMRB:16015, PDB:2KA6
Sequence:
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDLLSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYSCLKEERKILENAQRFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKSLEDLQDEYDFKCKTLQNREHETNGVAKSDQKQEQLLLKKMYLMLDNKRKEVVHKIIELLNVTELTQNALINDELVEWKRRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQVLWDRTFSLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKVKVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTNEGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPVVVISNVSQLPSGWASILWYNMLVAEPRNLSFFLTPPCARWAQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNASPDGLIPWTRFCKENINDKNFPFWLWIESILELIKKHLLPLWNDGCIMGFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIPENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTTDNLLPMSPEEFDEVSRIVGSVEFDSMMNTV
Protein: Secreted effector protein EspF(U)
UniProt accession: P0DJ89
Organism: Escherichia coli O157:H7
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: espF(U), tccP
Length: 337 residues
Disorder content (fraction disordered): 0.2789317507418398
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 293, 294, 294, 268, 294, 294, 294, 268, 268, 270, 270, 221, 246, 223, 247, 223, 247
Curated region end positions: 314, 306, 306, 314, 306, 306, 306, 314, 314, 288, 288, 267, 267, 241, 259, 241, 259
Curated region terms: disorder, disorder to order, SH3 domain binding, disorder, exogenous protein binding, adhesion of symbiont to host cell, positive regulation of actin nucleation, modulation by symbiont of host process, molecular adaptor activity, disorder to order, exogenous protein binding, disorder, disorder, exogenous protein binding, exogenous protein binding, disorder to order, disorder to order
Domain/feature annotations: TccP2/EspF(U)-like, TccP2/EspF(U)-like, TccP2/EspF(U)-like, TccP2/EspF(U)-like, TccP2/EspF(U)-like, TccP2/EspF(U)-like, EspF protein repeat, EspF protein repeat, EspF protein repeat, EspF protein repeat, EspF protein repeat, EspF protein repeat
Cross-references: BMRB:18165, BMRB:18165 , PDB:2LNH
Sequence:
MINNVSSLFPTVNRNITAVYKKSSFSVSPQKITLNPVKISSPFSPSSSSISATTLFRAPNAHSASFHRQSTAESSLHQQLPNVRQRLIQHLAEHGIKPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPLPVQNEQSRPLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
Protein: Preprotein translocase subunit SecG
UniProt accession: P60460
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Taxonomy: Archaea, Euryarchaeota, Methanomada group, Methanococci, Methanococcales, Methanocaldococcaceae, Methanocaldococcus
Gene names: MJ0912.1, secG
Length: 53 residues
Disorder content (fraction disordered): 0.37735849056603776
Curated region start positions: 1, 1
Curated region end positions: 20, 20
Curated region terms: disorder, disorder
Domain/feature annotations: Sec61beta family
Cross-references: PDB:1RH5, PDB:1RHZ, PDB:2YXQ, PDB:2YXR
Sequence:
MSKREETGLATSAGLIRYMDETFSKIRVKPEHVIGVTVAFVIIEAILTYGRFL
Protein: 50S ribosomal protein L18
UniProt accession: P09415
Organism: Geobacillus stearothermophilus
Taxonomy: Bacteria, Firmicutes, Bacilli, Bacillales, Bacillaceae, Geobacillus
Gene names: rplR
Length: 120 residues
Disorder content (fraction disordered): 0.19166666666666668
Curated region start positions: 1
Curated region end positions: 23
Curated region terms: disorder
Domain/feature annotations: 3.30.420.100, Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast
Cross-references: PDB:1OVY
Sequence:
MITKVDRNAVRKKRHARIRKKIFGTTERPRLSVFRSNKHIYAQIIDDTKSATIVSASTLDKEFGLDSTNNIEAAKKVGELVAKRALEKGIKQVVFDRGGYLYHGRVKALADAAREAGLEF