LiteFold/DisProt huggingface dataset:
Protein: SH3 domain-containing kinase-binding protein 1
UniProt accession: Q96B97
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CIN85, SH3KBP1
Length: 665 residues
Disorder content (fraction disordered): 0.1518796992481203
Dataset labels: Condensates-related proteins
Curated region start positions: 163, 163, 219, 219, 228, 219
Curated region end positions: 263, 263, 232, 232, 232, 232
Curated region terms: disorder, flexible linker, protein binding, disorder to order, phosphorylation display site, self-inhibition
Domain/feature annotations: Variant SH3 domain, Variant SH3 domain, Variant SH3 domain
Cross-references: BMRB:52081
Sequence:
MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMKKDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRRCQVAFSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIKELSGESDELGISQDEQLSKSSLRETTGSESDGGDSSSTKSEGANGTVATAAIQPKKVKGVGFGDIFKDKPIKLRPRSIEVENDFLPVEKTIGKKLPATTATPDSSKTEMDSRTKSKDYCKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLDLQKPSVPAIPPKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSSLSGILDKDLSDRSNDIDLEGFDSVVSSTEKLSHPTTSRPKATGRRPPSQSLTSSSLSSPDIFDSPSPEEDKEEHISLAHRGVDASKKTSKTVTISQVSDNKASLPPKPGTMAAGGGGPAPLSSAAPSPLSSSLGTAGHRANSPSLFGTEGKPKMEPAASSQAAVEELRTQVRELRSIIETMKDQQKREIKQLLSELDEEKKIRLRLQMEVNDIKKALQSK
Protein: Eukaryotic elongation factor 2 kinase
UniProt accession: O00418
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: EEF2K
Length: 725 residues
Disorder content (fraction disordered): 0.0496551724137931
Dataset labels: Autophagy-related proteins
Curated region start positions: 562
Curated region end positions: 597
Curated region terms: disorder
Domain/feature annotations: Alpha-kinase family
Sequence:
MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITDDPSSNQNVNSKVNKYYSNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEFHLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELKDRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERDAVNQNTKLLQSAKTILRGTEEKCGSPQVRTLSGSRPPLLRPLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGELDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQRLNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKGEEWDQESAVFHLEHAANLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQNLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGLEKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQMEE
Protein: Sorbin and SH3 domain-containing protein 1
UniProt accession: Q9BX66
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIAA0894, KIAA1296, SH3D5, SORBS1
Length: 1292 residues
Disorder content (fraction disordered): 0.013157894736842105
Curated region start positions: 851, 851
Curated region end positions: 867, 867
Curated region terms: disorder, flexible linker
Domain/feature annotations: SH3 domain, Sorbin homologous domain, Variant SH3 domain, Variant SH3 domain
Sequence:
MSSECDGGSKAVMNGLAPGSNGQDKATADPLRARSISAVKIIPVKTVKNASGLVLPTDMDLTKICTGKGAVTLRASSSYRETPSSSPASPQETRQHESKPGLEPEPSSADEWRLSSSADANGNAQPSSLAAKGYRSVHPNLPSDKSQDATSSSAAQPEVIVVPLYLVNTDRGQEGTARPPTPLGPLGCVPTIPATASAASPLTFPTLDDFIPPHLQRWPHHSQPARASGSFAPISQTPPSFSPPPPLVPPAPEDLRRVSEPDLTGAVSSTDSSPLLNEVSSSLIGTDSQAFPSVSKPSSAYPSTTIVNPTIVLLQHNREQQKRLSSLSDPVSERRVGEQDSAPTQEKPTSPGKAIEKRAKDDSRRVVKSTQDLSDVSMDEVGIPLRNTERSKDWYKTMFKQIHKLNRDTPEENPYFPTYKFPELPEIQQTSEEDNPYTPTYQFPASTPSPKSEDDDSDLYSPRYSFSEDTKSPLSVPRSKSEMSYIDGEKVVKRSATLPLPARSSSLKSSSERNDWEPPDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGKPPPKKIWDYTPGDCSILPREDRKTNLDKDLSLCQTELEADLEKMETLNKAPSANVPQSSAISPTPEISSETPGYIYSSNFHAVKRESDGAPGDLTSLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGSEMRPARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHSKLITPAPSSLPHSRRALSPEMHAVTSEWISLTVGVPGRRSLALTPPLPPLPEASIYNTDHLALSPRASPSLSLSLPHLSWSDRPTPRSVASPLALPSPHKTYSLAPTSQASLHMNGDGGVHTPSSGIHQDSFLQLPLGSSDSVISQLSDAFSSQSKRQPWREESGQYERKAERGAGERGPGGPKISKKSCLKPSDVVRCLSTEQRLSDLNTPEESRPGKPLGSAFPGSEAEQTERHRGGEQAGRKAARRGGSQQPQAQQRRVTPDRSQTSQDLFSYQALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPLYL
Protein: Transcriptional regulator SutA
UniProt accession: A0A0H2ZJC1
Organism: Pseudomonas aeruginosa (strain UCBPP-PA14)
Taxonomy: Bacteria, Pseudomonadota, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: PA14_69770, sutA
Length: 105 residues
Disorder content (fraction disordered): 0.8
Curated region start positions: 1, 77, 77, 1, 95, 1
Curated region end positions: 55, 105, 105, 55, 99, 55
Curated region terms: disorder, disorder, flexible C-terminal tail, flexible N-terminal tail, protein binding, positive regulation of transcription, DNA-templated
Domain/feature annotations: SutA RNAP-binding domain
Sequence:
MSEEELEQDELDGADEDDGEELAAADDGEADSSDGDEAPAPGKKAKAAVVEEELPSVEAKQKERDALAKAMEEFLSRGGKVQEIEPNVVADPPKKPDSKYGSRPI
Protein: Phosphopantetheine-binding protein
UniProt accession: Q0B311
Organism: Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)
Taxonomy: Bacteria, Pseudomonadota, Betaproteobacteria, Burkholderiales, Burkholderiaceae, Burkholderia, Burkholderia cepacia complex
Gene names: Bamb_5917
Length: 315 residues
Disorder content (fraction disordered): 0.06349206349206349
Curated region start positions: 296, 296, 307
Curated region end positions: 315, 315, 315
Curated region terms: disorder, flexible C-terminal tail, protein binding
Domain/feature annotations: Phosphopantetheine attachment site
Cross-references: BMRB:27304, BMRB:34085, PDB:5MTI
Sequence:
MVSAPRQAVLPASPTVSNQADDAMTLATLQAAETADIIVLSAPGVDALRGAVWQLLGQLRALASDAAAEPFTLADLAYTLKSRPEAGGCRVAFVTRQLDDLAAGLEHYLRAHAQAEASVPRSVTPGRHGELVTILRGDLAADSGTARLLTGAAAATMARALWAARDLENLALIWVRGGQLDWDALREGPPPRRLAWPDQAPLEAGARPAPEAFEGAAAGVSAAGIEPDLTAIWQALFALPAVGRHQDFFALGGDSQLGLRMLAQLRERHGVDLPLRCLYEAPTVARLAETIVRLAAPAPSGDQDDASEYEEGVIR
Protein: Translocated intimin receptor Tir
UniProt accession: B7UM99
Organism: Escherichia coli O127:H6 (strain E2348/69 / EPEC)
Taxonomy: Bacteria, Pseudomonadota, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: E2348C_3941, espE, tir
Length: 550 residues
Disorder content (fraction disordered): 0.5072727272727273
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 198, 1, 388, 388, 198, 452, 472, 481, 509, 388, 509, 454, 483, 35, 35, 35, 35, 65, 490, 490
Curated region end positions: 233, 80, 550, 550, 233, 456, 476, 485, 513, 550, 515, 511, 515, 77, 53, 53, 53, 75, 550, 550
Curated region terms: disorder, disorder, disorder, disorder, disorder, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, disorder, SH2 domain binding, SH2 domain binding, lipid binding, protein binding, chaperone binding, order, disorder to order, chaperone binding, chaperone binding, chaperone binding
Domain/feature annotations: Translocated intimin receptor (Tir) intimin-binding domain, Translocated intimin receptor (Tir) C-terminus, Translocated intimin receptor (Tir) N-terminus
Cross-references: BMRB:50758, BMRB:50759, PDB:5WEZ
Sequence:
MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADSVDSRDIPGLPTNPSRLAAATSETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADGTHAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGRGGSGHPMVTVASDIAEARTKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSVGAIAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTTTHTVVQQQTGGNTPAQGGTDATRAEDASLNRRDSQGSVASTHWSDSSSEVVNPYAEVGGARNSLSAHQPEEHIYDEVAADPGYSVIQNFSGSGPVTGRLIGTPGQGIQSTYALLANSGGLRLGMGGLTSGGESAVSSVNAAPTPGPVRFV
Protein: Isoform Short of Beta-arrestin-2
UniProt accession: P32120-2
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: ARRB2
Length: 409 residues
Disorder content (fraction disordered): 0.1100244498777506
Curated region start positions: 350, 349
Curated region end positions: 393, 385
Curated region terms: disorder, disorder
Cross-references: PDB:3P2D, PDB:5TV1
Sequence:
MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQSAAPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
Protein: SAM and SH3 domain-containing protein 1
UniProt accession: O94885
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIAA0790, PEPE1, SASH1
Length: 1247 residues
Disorder content (fraction disordered): 0.1355252606255012
Curated region start positions: 396
Curated region end positions: 564
Curated region terms: disorder
Domain/feature annotations: SAM domain (Sterile alpha motif), SAM domain (Sterile alpha motif), Variant SH3 domain, SLy Proteins Associated Disordered Region, SASH1 homeodomain-like domain, SASH1 homeodomain-like domain
Cross-references: BMRB:51747
Sequence:
MEDAGAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGSLGNIDDLAQQYADYYNTCFSDVCERMEELRKRRVSQDLEVEKPDASPTSLQLRSQIEESLGFCSAVSTPEVERKNPLHKSNSEDSSVGKGDWKKKNKYFWQNFRKNQKGIMRQTSKGEDVGYVASEITMSDEERIQLMMMVKEKMITIEEALARLKEYEAQHRQSAALDPADWPDGSYPTFDGSSNCNSREQSDDETEESVKFKRLHKLVNSTRRVRKKLIRVEEMKKPSTEGGEEHVFENSPVLDERSALYSGVHKKPLFFDGSPEKPPEDDSDSLTTSPSSSSLDTWGAGRKLVKTFSKGESRGLIKPPKKMGTFFSYPEEEKAQKVSRSLTEGEMKKGLGSLSHGRTCSFGGFDLTNRSLHVGSNNSDPMGKEGDFVYKEVIKSPTASRISLGKKVKSVKETMRKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSTSNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSEDEEKPKRPTRRRRKGRPPQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEYDSNSDQSGSQEKLLVDSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSTEPSLKSFSRNQLGNYPTLPLMKSGDALKQGQEEGRLGGGLAPDTSKSCDPPGVTGLNKNRRSLPVSICRSCETLEGPQTVDTWPRSHSLDDLQVEPGAEQDVPTEVTEPPPQIVPEVPQKTTASSTKAQPLEQDSAVDNALLLTQSKRFSEPQKLTTKKLEGSIAASGRGLSPPQCLPRNYDAQPPGAKHGLARTPLEGHRKGHEFEGTHHPLGTKEGVDAEQRMQPKIPSQPPPVPAKKSRERLANGLHPVPMGPSGALPSPDAPCLPVKRGSPASPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELPENTSLQEHGVKLGPALTRKVSCARGVDLETLTENKLHAEGIDLTEEPYSDKHGRCGIPEALVQRYAEDLDQPERDVAANMDQIRVKQLRKQHRMAIPSGGLTEICRKPVSPGCISSVSDWLISIGLPMYAGTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLPPGPEAM
Protein: Pheromone binding protein 3
UniProt accession: E7CC86
Organism: Ostrinia nubilalis
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Lepidoptera, Glossata, Ditrysia, Pyraloidea, Crambidae, Pyraustinae, Ostrinia
Gene names: OnubPBP3, PBP3
Length: 166 residues
Disorder content (fraction disordered): 0.12048192771084336
Curated region start positions: 147, 147
Curated region end positions: 166, 166
Curated region terms: disorder, flexible C-terminal tail
Domain/feature annotations: PBP/GOBP family
Cross-references: BMRB:51937
Sequence:
MWLPKTLVVMAVMSSMSVVVHSSQTVMREMTRNFIKAYEVCAKEYNLPEATGSELINFWKEGHELTTREAGCAILCMSTKLNLLDVQGSVHRGNTVEFAKHHGSDDAMAHQVVDILHACEKATPNEDKCMLALSIAMCFKAEIHKLDWAPNHELMFEELVSDMWNS
Protein: Kinesin heavy chain isoform 5C
UniProt accession: P56536
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Kif5c, Nkhc2
Length: 955 residues
Disorder content (fraction disordered): 0.014659685863874346
Curated region start positions: 325, 325, 325
Curated region end positions: 338, 338, 338
Curated region terms: disorder, flexible linker, disorder
Domain/feature annotations: Kinesin motor domain
Cross-references: BMRB:52075, PDB:8TT7
Sequence:
MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGEETVVIGQGKPYVFDRVLPPNTTQEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKALKSVIQHLEVELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNITPVVDGISAEKEKYDEEITSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQTDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEVKKALEQQMESHREAHQKQLSRLRDEIEEKQRIIDEIRDLNQKLQLEQERLSSDYNKLKIEDQEREVKLEKLLLLNDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDSDDGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAVRGGGGSSNSTHYQK
Protein: NAD-dependent protein deacylase sirtuin-6
UniProt accession: Q8N6T7
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SIR2L6, SIRT6
Length: 355 residues
Disorder content (fraction disordered): 0.3774647887323944
Curated region start positions: 284, 1, 62, 293, 330, 293, 270, 270, 270, 293, 270, 290, 345, 272
Curated region end positions: 355, 25, 84, 355, 348, 355, 355, 355, 355, 344, 355, 355, 351, 355
Curated region terms: disorder, disorder, disorder, nucleosome binding, nucleosome binding, DNA binding, disorder, DNA binding, histone deacetylase activity (H3-K9 specific), chromatin binding, nucleosomal DNA binding, protein import into nucleus, protein import into nucleus, protein import into nucleus
Domain/feature annotations: Sir2 family
Cross-references: EMDB:16845, PDB:8OF4
Sequence:
MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
Protein: Myc box-dependent-interacting protein 1
UniProt accession: O00499
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AMPHL, BIN1
Length: 593 residues
Disorder content (fraction disordered): 0.06913996627318718
Dataset labels: Age-related disorders proteins
Curated region start positions: 1, 12, 1, 1, 1, 1, 8, 10, 1, 1, 1
Curated region end positions: 41, 30, 33, 33, 33, 33, 33, 33, 33, 33, 33
Curated region terms: disorder, lipid binding, disorder, disorder to order, lipid binding, disorder, disorder to order, disorder to order, lipid tube assembly, membrane fusion, membrane tubulation
Domain/feature annotations: BAR domain, Variant SH3 domain
Cross-references: PDB:2FIC, PDB:2RMY, PDB:2RND
Sequence:
MAEMGSKGVTAGKIASNVQKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFNKQLTEGTRLQKDLRTYLASVKAMHEASKKLNECLQEVYEPDWPGRDEANKIAENNDLLWMDYHQKLVDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDSARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVPEISVTTPSQFEAPGPFSEQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEASEVAGGTQPAAGAQEPGETAASEAASSSLPAVVVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP
Protein: Pheromone-binding protein
UniProt accession: P34174
Organism: Bombyx mori
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Lepidoptera, Glossata, Ditrysia, Bombycoidea, Bombycidae, Bombycinae, Bombyx
Length: 164 residues
Disorder content (fraction disordered): 0.08536585365853659
Curated region start positions: 151
Curated region end positions: 164
Curated region terms: disorder
Domain/feature annotations: PBP/GOBP family
Cross-references: PDB:1LS8
Sequence:
MSIQGQIALALMVNMAVGSVDASQEVMKNLSLNFGKALDECKKEMTLTDAINEDFYNFWKEGYEIKNRETGCAIMCLSTKLNMLDPEGNLHHGNAMEFAKKHGADETMAQQLIDIVHGCEKSTPANDDKCIWTLGVATCFKAEIHKLNWAPSMDVAVGEILAEV
Protein: Isoform 1 of Zinc finger protein DPF3
UniProt accession: Q92784-1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BAF45C, CERD4, DPF3
Length: 378 residues
Disorder content (fraction disordered): 0.47354497354497355
Curated region start positions: 60, 222
Curated region end positions: 200, 259
Curated region terms: disorder, disorder
Sequence:
MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNEEEDLEEDIPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCDICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA
Protein: RNA-binding protein Musashi homolog 1
UniProt accession: Q61474
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Msi1, Msi1h
Length: 362 residues
Disorder content (fraction disordered): 0.49171270718232046
Dataset labels: RNA-binding proteins, Condensates-related proteins
Curated region start positions: 185, 194, 194, 194
Curated region end positions: 200, 362, 362, 362
Curated region terms: disorder, disorder, protein homodimerization activity, molecular condensate scaffold activity
Domain/feature annotations: RNA recognition motif, RNA recognition motif
Cross-references: BMRB:50204, PDB:5X3Y
Sequence:
METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRSRGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRRAQPKMVTRTKKIFVGGLSVNTTVEDVKHYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKMVECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPGYTYQFPEFRVERSPLPSAPVLPELTAIPLTAYGPMAAAAAAAAVVRGTGSHPWTMAPPPGSTPSRTGGFLGTTSPGPMAELYGAANQDSGVSSYISAASPAPSTGFGHSLGGPLIATAFTNGYH
Protein: Telomerase Cajal body protein 1
UniProt accession: Q9BUR4
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: TCAB1, WDR79, WRAP53
Length: 548 residues
Disorder content (fraction disordered): 0.41605839416058393
Curated region start positions: 1, 199, 442, 486, 511
Curated region end positions: 150, 209, 452, 503, 548
Curated region terms: disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: WD domain, G-beta repeat, WD domain, G-beta repeat, WD domain, G-beta repeat, WD domain, G-beta repeat
Cross-references: EMDB:12177, PDB:7BGB
Sequence:
MKTLETQPLAPDCCPSDQDPAPAHPSPHASPMNKNADSELMPPPPERGDPPRLSPDPVAGSAVSQELREGDPVSLSTPLETEFGSPSELSPRIEEQELSENTSLPAEEANGSLSEEEANGPELGSGKAMEDTSGEPAAEDEGDTAWNYSFSQLPRFLSGSWSEFSTQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYHEGEQVEYAEMVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQGEKGQGGTEGGVGELI
Protein: tRNA pseudouridine synthase 1
UniProt accession: Q12211
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: PUS1, YPL212C
Length: 544 residues
Disorder content (fraction disordered): 0.2849264705882353
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 254, 254, 464, 464, 494
Curated region end positions: 71, 266, 266, 483, 483, 544
Curated region terms: disorder, disorder, flexible linker, disorder, flexible linker, disorder
Domain/feature annotations: tRNA pseudouridine synthase
Cross-references: PDB:7R9F
Sequence:
MSEENLRPAYDDQVNEDVYKRGAQSKLTKARKADFDDEKDKKKDNDKHIDKRPKSGPRLDENGNPLPKEPRLPKRKVAVMVGYCGTGYHGMQYNPPNPTIESALFKAFVEAGAISKDNSNDLKKNGFMRAARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWYEYLLPTYSLIGPKPGSILYRDIEESKTELPGVLDEDLESKEFWEEFKKDANEKFSTEEIEAILAYVPPARDEFDINEELYQKVKKYKQLENAHRRRYRISAAKLAKFRASTSQYLGAHNFHNFTLGKDFKEPSAIRFMKDIKVSDPFVIGDAQTEWISIKIHGQSFMLHQIRKMVSMATLITRCGCPVERISQAYGQQKINIPKAPALGLLLEAPVFEGYNKRLEQFGYKAIDFSKYQDEVDKFKMKHIYDKIYKEEVDENVFNAFFSYIDSFNKVTGAQGEETADKSGPAVQKSIFEFLTAKGIPGLTDAPESNKKIKQRKRMEEEEAASKKAEISSTTQSNEPEVQPEAAAN
Protein: Multisubstrate pseudouridine synthase 7
UniProt accession: Q08647
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: O5254, PUS7, YOR243C
Length: 676 residues
Disorder content (fraction disordered): 0.2781065088757396
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 485, 662, 87
Curated region end positions: 36, 506, 676, 201
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: tRNA pseudouridine synthase D (TruD)
Cross-references: PDB:7MZV
Sequence:
MSDSSEATVKRPLDAHVGPSENAAKKLKIEQRTQADGIHEADVGITLFLSPELPGFRGQIKQRYTDFLVNEIDQEGKVIHLTDKGFKMPKKPQRSKEEVNAEKESEAARRQEFNVDPELRNQLVEIFGEEDVLKIESVYRTANKMETAKNFEDKSVRTKIHQLLREAFKNELESVTTDTNTFKIARSNRNSRTNKQEKINQTRDANGVENWGYGPSKDFIHFTLHKENKDTMEAVNVITKLLRVPSRVIRYAGTKDRRAVTCQRVSISKIGLDRLNALNRTLKGMIIGNYNFSDASLNLGDLKGNEFVVVIRDVTTGNSEVSLEEIVSNGCKSLSENGFINYFGMQRFGTFSISTHTIGRELLLSNWKKAAELILSDQDNVLPKSKEARKIWAETKDAALALKQMPRQCLAENALLYSLSNQRKEEDGTYSENAYYTAIMKIPRNLRTMYVHAYQSYVWNSIASKRIELHGLKLVVGDLVIDTSEKSPLISGIDDEDFDEDVREAQFIRAKAVTQEDIDSVKYTMEDVVLPSPGFDVLYPSNEELKQLYVDILKADNMDPFNMRRKVRDFSLAGSYRTVIQKPKSLEYRIIHYDDPSQQLVNTDLDILNNTRAKESGQKYMKAKLDRYMPDKGGEKTAVVLKFQLGTSAYATMALRELMKLETSRRGDMCDVKENI
Protein: tRNA pseudouridine synthase B
UniProt accession: P9WHP7
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Taxonomy: Bacteria, Actinomycetota, Actinomycetes, Mycobacteriales, Mycobacteriaceae, Mycobacterium, Mycobacterium tuberculosis complex
Gene names: MTV002.58c, Rv2793c, truB
Length: 298 residues
Disorder content (fraction disordered): 0.09395973154362416
Curated region start positions: 112
Curated region end positions: 139
Curated region terms: disorder
Domain/feature annotations: TruB family pseudouridylate synthase (N terminal domain), tRNA Pseudouridine synthase II, C terminal, tRNA pseudouridylate synthase B C-terminal domain
Cross-references: PDB:1SGV
Sequence:
MSATGPGIVVIDKPAGMTSHDVVGRCRRIFATRRVGHAGTLDPMATGVLVIGIERATKILGLLTAAPKSYAATIRLGQTTSTEDAEGQVLQSVPAKHLTIEAIDAAMERLRGEIRQVPSSVSAIKVGGRRAYRLARQGRSVQLEARPIRIDRFELLAARRRDQLIDIDVEIDCSSGTYIRALARDLGDALGVGGHVTALRRTRVGRFELDQARSLDDLAERPALSLSLDEACLLMFARRDLTAAEASAAANGRSLPAVGIDGVYAACDADGRVIALLRDEGSRTRSVAVLRPATMHPG