LiteFold/DisProt huggingface dataset:
Protein: Lactotransferrin
UniProt accession: P02788
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GIG12, LF, LTF
Length: 710 residues
Disorder content (fraction disordered): 0.030985915492957747
Curated region start positions: 38, 38, 38, 38, 38, 38
Curated region end positions: 59, 59, 59, 59, 59, 59
Curated region terms: disorder, molecular function regulator, disorder, molecular function regulator, disorder, molecular function regulator
Domain/feature annotations: Periplasmic binding protein-like II, Periplasmic binding protein-like II, Periplasmic binding protein-like II, Periplasmic binding protein-like II, Transferrin, Transferrin
Sequence:
MKLVFLVLLFLGALGLCLAGRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGGSFQLNELQGLKSCHTGLRRTAGWNVPIGTLRPFLNWTGPPEPIEAAVARFFSASCVPGADKGQFPNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGFSRVPPRIDSGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWSGLSEGSVTCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQTGSCKFDEYFSQSCAPGSDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVSRMDKVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSETKNLLFNDNTECLARLHGKTTYEKYLGPQYVAGITNLKKCSTSPLLEACEFLRK
Protein: 26S proteasome complex subunit SEM1
UniProt accession: P60896
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: C7orf76, DSS1, SEM1, SHFDG1, SHFM1
Length: 70 residues
Disorder content (fraction disordered): 0.7285714285714285
Curated region start positions: 26, 1, 38
Curated region end positions: 36, 51, 46
Curated region terms: disorder, disorder, ubiquitin binding
Domain/feature annotations: DSS1/SEM1 family
Cross-references: BMRB:50906, PDB:1MIU
Sequence:
MSEKKQPVDLGLLEEDDEFEEFPAEDWAGLDEDEDAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKMETS
Protein: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
UniProt accession: P53954
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: ALG11, N2510, YNL048W, YNL2510W
Length: 548 residues
Disorder content (fraction disordered): 0.025547445255474453
Curated region start positions: 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79, 79
Curated region end positions: 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92, 92
Curated region terms: disorder, molecular function regulator, disorder to order, protein binding, disorder, molecular function regulator, disorder to order, protein binding, disorder, molecular function regulator, disorder to order, protein binding, disorder, molecular function regulator, disorder to order, protein binding, disorder, molecular function regulator, disorder to order, protein binding
Domain/feature annotations: Glycogen Phosphorylase B;, Glycosyl transferases group 1, ALG11 mannosyltransferase N-terminus
Sequence:
MGSAWTNYNFEEVKSHFGFKKYVVSSLVLVYGLIKVLTWIFRQWVYSSLNPFSKKSSLLNRAVASCGEKNVKVFGFFHPYCNAGGGGEKVLWKAVDITLRKDAKNVIVIYSGDFVNGENVTPENILNNVKAKFDYDLDSDRIFFISLKLRYLVDSSTWKHFTLIGQAIGSMILAFESIIQCPPDIWIDTMGYPFSYPIIARFLRRIPIVTYTHYPIMSKDMLNKLFKMPKKGIKVYGKILYWKVFMLIYQSIGSKIDIVITNSTWTNNHIKQIWQSNTCKIIYPPCSTEKLVDWKQKFGTAKGERLNQAIVLAQFRPEKRHKLIIESFATFLKNLPDSVSPIKLIMAGSTRSKQDENYVKSLQDWSENVLKIPKHLISFEKNLPFDKIEILLNKSTFGVNAMWNEHFGIAVVEYMASGLIPIVHASAGPLLDIVTPWDANGNIGKAPPQWELQKKYFAKLEDDGETTGFFFKEPSDPDYNTTKDPLRYPNLSDLFLQITKLDYDCLRVMGARNQQYSLYKFSDLKFDKDWENFVLNPICKLLEEEERG
Protein: Selenocysteine lyase
UniProt accession: Q68FT9
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Scly
Length: 432 residues
Disorder content (fraction disordered): 0.04398148148148148
Curated region start positions: 374, 374
Curated region end positions: 392, 392
Curated region terms: disorder, disorder to order
Domain/feature annotations: Type I PLP-dependent aspartate aminotransferase-like (Major domain), Aspartate Aminotransferase, domain 1, 1.10.260.50, Aminotransferase class-V
Sequence:
MDVARNGARGSVESPPNRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTVEHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGVGKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKRIHLNSRFPGVERLPNTCNFSIQGSQLRGYMVLAQCQTLLASVGASCHSDHEDRPSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQLEGPV
Protein: Complement C1r subcomponent
UniProt accession: P00736
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: C1R
Length: 705 residues
Disorder content (fraction disordered): 0.16028368794326242
Curated region start positions: 193, 193, 193, 193, 193, 193
Curated region end positions: 305, 305, 305, 305, 305, 305
Curated region terms: disorder, molecular sequestering activity, disorder to order, disorder, molecular sequestering activity, disorder to order
Domain/feature annotations: Spermadhesin, CUB domain, Spermadhesin, CUB domain, Complement Module, domain 1, Laminin, Complement Module, domain 1, Trypsin-like serine proteases, Trypsin-like serine proteases, Sushi repeat (SCR repeat), Sushi repeat (SCR repeat), Trypsin, CUB domain, CUB domain, Coagulation Factor Xa inhibitory site
Sequence:
MWLLYLLVPALFCRAGGSIPIPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPDLRCNYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGKQRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTIIQNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRNLPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKGEKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFLGHTNVEELMKLGNHPIRRVSVHPDYRQDESYNFEGDIALLELENSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEEKIAHDLRFVRLPVANPQACENWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEEED
Protein: Vesicle-associated membrane protein 2
UniProt accession: P63045
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Syb2, Vamp2
Length: 116 residues
Disorder content (fraction disordered): 0.7586206896551724
Curated region start positions: 1, 1, 1, 36, 36, 36, 36, 55, 55, 55, 77, 77, 77, 77, 2
Curated region end positions: 35, 35, 35, 54, 54, 54, 54, 76, 76, 76, 88, 88, 88, 88, 24
Curated region terms: disorder, molecular adaptor activity, lipid binding, disorder, molecular adaptor activity, disorder to order, lipid binding, disorder, molecular adaptor activity, lipid binding, disorder, molecular adaptor activity, disorder to order, lipid binding, disorder
Domain/feature annotations: Synaptobrevin
Sequence:
MSATAATVPPAAPAGEGGPPAPPPNLTSNRRLQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNLKMMIILGVICAIILIIIIVYFST
Protein: DNA damage-inducible transcript 3 protein
UniProt accession: P35638
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CHOP, CHOP10, DDIT3, GADD153
Length: 169 residues
Disorder content (fraction disordered): 0.9940828402366864
Dataset labels: Autophagy-related proteins, Cancer-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 168, 168, 168, 120, 168, 168
Curated region terms: disorder, regulation of transcription by RNA polymerase II, disorder, disorder, pre-molten globule, identical protein binding
Domain/feature annotations: 1.20.5.170, Basic region leucine zipper
Sequence:
MAAESLPFSFGTLSSWELEAWYEDLQEVLSSDENGGTYVSPPGNEEEESKIFTTLDPASLAWLTEEEPEPAEVTSTSQSPHSPDSSQSSLAQEEEEEDQGRTRKRKQSGHSPARAGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQA
Protein: Pre-mRNA polyadenylation factor FIP1
UniProt accession: P45976
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: FIP1, J1911, YJR093C
Length: 327 residues
Disorder content (fraction disordered): 0.3547400611620795
Curated region start positions: 80, 80, 80, 80, 80, 80, 80, 80, 80
Curated region end positions: 195, 195, 195, 195, 195, 195, 195, 195, 195
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder to order, protein binding, disorder, disorder to order, protein binding
Domain/feature annotations: Fip1 motif
Sequence:
MSSSEDEDDKFLYGSDSELALPSSKRSRDDEADAGASSNPDIVKRQKFDSPVEETPATARDDRSDEDIYSDSSDDDSDSDLEVIISLGPDPTRLDAKLLDSYSTAATSSSKDVISVATDVSNTITKTSDERLITEGEANQGVTATTVKATESDGNVPKAMTGSIDLDKEGIFDSVGITTIDPEVLKEKPWRQPGANLSDYFNYGFNEFTWMEYLHRQEKLQQDYNPRRILMGLLSLQQQGKLNSANDTDSNLGNIIDNNNNVNNANMSNLNSNMGNSMSGTPNPPAPPMHPSFPPLPMFGSFPPFPMPGMMPPMNQQPNQNQNQNSK
Protein: Protein UmuD
UniProt accession: P0AG11
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1172, b1183, umuD
Length: 139 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 139, 139, 139, 139
Curated region terms: disorder, molecular function regulator, molten globule to order, nucleic acid binding
Domain/feature annotations: Umud Fragment, subunit A, Peptidase S24-like
Sequence:
MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLLIQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLRPTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR
Protein: Prostatic acid phosphatase
UniProt accession: P15309
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ACP3, ACPP
Length: 386 residues
Disorder content (fraction disordered): 0.1010362694300518
Curated region start positions: 248, 248, 248
Curated region end positions: 286, 286, 286
Curated region terms: disorder, molecular adaptor activity, disorder to order
Domain/feature annotations: Phosphoglycerate mutase-like, Histidine phosphatase superfamily (branch 2)
Sequence:
MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
Protein: Nucleoprotein
UniProt accession: Q07097
Organism: Sendai virus (strain Fushimi)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Paramyxoviridae, Orthoparamyxovirinae, Respirovirus
Gene names: N, NP
Length: 524 residues
Disorder content (fraction disordered): 0.2366412213740458
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 443, 473, 401, 476, 473, 401
Curated region end positions: 524, 492, 524, 489, 492, 524
Curated region terms: disorder, protein binding, disorder, disorder to order, molecular adaptor activity, disorder
Domain/feature annotations: Paramyxovirus nucleocapsid protein
Sequence:
MAGLLSTFDTFSSRRSESINKSGGGAVIPGQRSTVSVFVLGPSVTDDADKLFIATTFLAHSLDTDKQHSQRGGFLVSLLAMAYSSPELYLTTNGVNADVKYVIYNIEKDPKRTKTDGFIVKTRDMEYERTTEWLFGPMVNKSPLFQGQRVAADPDTLLQTYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFRQDGTVKGALVFTGETVEGIGSVMRSQQSLVSLMVETLVTMNTARSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLIDTYLSKGPRAPFICILKDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGGTYLDMEMFLLGQAVAKDAESKISSALEDELGVTDTAKERLRHHLANLSGGDGAYHEPTGGGAIEVALDNADIDLETEAHADQDARGWGGESGERWARQVSGGHFVTLHGAERLEEETNDEDVSDIERRIAMRLAERRQEDSATHGDEGRNNGVDHDEDDDAAAVAGIGGI
Protein: Gamma-synuclein
UniProt accession: O76070
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BCSG1, PERSYN, PRSN, SNCG
Length: 127 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 127, 127, 127, 127, 127, 127
Curated region terms: disorder, molecular function regulator, protein binding, disorder, molecular function regulator, protein binding
Domain/feature annotations: Helix hairpin bin, Synuclein
Sequence:
MDVFKKGFSIAKEGVVGAVEKTKQGVTEAAEKTKEGVMYVGAKTKENVVQSVTSVAEKTKEQANAVSEAVVSSVNTVATKTVEEAENIAVTSGVVRKEDLRPSAPQQEGEASKEKEEVAEEAQSGGD
Protein: Protein SIC1
UniProt accession: P38634
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: L9449.8, SDB25, SIC1, YLR079W
Length: 284 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 31, 3, 31, 43, 67, 74, 78, 1, 1, 1
Curated region end positions: 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 284, 190, 7, 35, 47, 71, 78, 82, 90, 90, 90
Curated region terms: disorder, molecular function regulator, protein binding, disorder, molecular function regulator, protein binding, disorder, molecular function regulator, protein binding, disorder, molecular function regulator, protein binding, disorder, disorder, protein binding, disorder, disorder, disorder to molten globule, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, SCF ubiquitin ligase complex binding, protein binding, SCF ubiquitin ligase complex binding
Sequence:
MTPSTPPRSRGTRYLAQPSGNTSSSALMQGQKTPQKPSQNLVPVTPSTTKSFKNAPLLAPPNSNMGMTSPFNGLTSPQRSPFPKSSVKRTLFQFESHDNGTVREEQEPLGRVNRILFPTQQNVDIDAAEEEEEGEVLLPPSRPTSARQLHLSLERDEFDQTHRKKIIKDVPGTPSDKVITFELAKNWNNNSPKNDARSQESEDEEDIIINPVRVGKNPFASDELVTQEIRNERKRAMLRENPDIEDVITYVNKKGEVVEKRRLTDEEKRRFKPKALFQSRDQEH
Protein: Kinesin-like protein bimC
UniProt accession: P17120
Organism: Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Pezizomycotina, Eurotiomycetes, Eurotiomycetidae, Eurotiales, Aspergillaceae, Aspergillus, Aspergillus subgen. Nidulantes
Gene names: AN3363, bimC
Length: 1184 residues
Disorder content (fraction disordered): 0.059966216216216214
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 71, 71, 71, 71, 71, 71, 71, 71, 71, 71
Curated region terms: disorder, flexible N-terminal tail, molecular adaptor activity, molecular function regulator, protein binding, disorder, flexible N-terminal tail, molecular adaptor activity, molecular function regulator, protein binding
Domain/feature annotations: Kinesin motor domain, Kinesin motor domain, Kinesin-associated microtubule-binding
Sequence:
MAGPQRATSGLPTRRTTTRQPTRRAGSAIPERQTSTASPAVSTKTAAISRTRTLKSPGEPASVLAKRKERDIEREINEDTSIHVVVRCRGRNEREVKENSGVVLQTEGVKGKTVELSMGPNAVSNKTYTFDKVFSAAADQITVYEDVVLPIVTEMLAGYNCTIFAYGQTGTGKTYTMSGDMTDTLGILSDNAGIIPRVLYSLFAKLADTESTVKCSFIELYNEELRDLLSAEENPKLKIYDNEQKKGHMSTLVQGMEETYIDSATAGIKLLQQGSHKRQVAATKCNDLSSRSHTVFTITVNIKRTTESGEEYVCPGKLNLVDLAGSENIGRSGAENKRATEAGLINKSLLTLGRVINALVDKSQHIPYRESKLTRLLQDSLGGRTKTCIIATISPARSNLEETISTLDYAFRAKNIRNKPQINSTMPKMTLLREFTAEIEKLKAELIATRHRNGVYMSVESYEEMKMENESRRIISEEQRAKIESMESSLRHKVQELLTLTSKFNDLKKDNDDTLAALCSTNDVLQQTDIVLQNTRAQLEEEEMLRCAHEETEHQLQDVGKGLISTLGQTVEDINSLQSKLDRKAELDATNAELWRASSTEVSDVTKRIDQRVEAFQTRHAKLLETTSVKVNEFIATEISNIERTRSDLSEYNRSLDAACNNAKAETSSAHEDMNNVLEEIKDLREEVKSKVGEGLNGLSAAAARISEEVIGEFTQLHSQLHTSFNNLGKDLKSIFETMATHLSEQKNEINRLRAELQSSNRQNIETTHKASAHLAQAIEEEHVAAEAEREILMSQIKALVEESRQKQFARLRAKIDGVRTEISASGDMLEQATTQHDRQIDEWVFKSEQFAKDVNASKDEIRTKLQNDWEAFDQRNSTIRKATESVHKETVRIVDVQVDDMGRQMEALDDFVAKARSQNGRYRDAHIATLDTIATGVRDSYSSIEGRVENLTGRMNQFQQEATHHHATLEESIAPLSNDVRKPLTDLSSSFQNRSLEEYVATGVTPKKRKYDYISVLPSTESHEVLKSRLRTTKEMEVLPFNSDDQLSGPSSSPGGSPSKGFVYNDVEDEVGTHAPTVTNVNPSNTGLREVDANVAARPLVYSTGEKSTDQDGSPVVSPDSATEAEGMNGPPSKRRRSNSVVADTKLPNKMLARRMAGMMEGRENVPPPGISNGRRLRGRPSP
Protein: Eotaxin
UniProt accession: P51671
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CCL11, SCYA11
Length: 97 residues
Disorder content (fraction disordered): 0.31958762886597936
Curated region start positions: 1, 1, 1
Curated region end positions: 31, 31, 31
Curated region terms: disorder, molecular function regulator, protein binding
Domain/feature annotations: 2.40.50.40, Small cytokines (intecrine/chemokine), interleukin-8 like
Cross-references: PDB:1EOT
Sequence:
MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
Protein: Bcl-2-modifying factor
UniProt accession: Q91ZE9
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Bmf
Length: 185 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 185, 185, 185, 185, 185, 185, 185, 185
Curated region terms: disorder, protein binding, disorder, protein binding, disorder, protein binding, disorder, protein binding
Domain/feature annotations: Bcl-2-modifying factor, apoptosis
Sequence:
MEPPQCVEELEDDVFQSEDGEPGTQPGGLLSADLFAQSQLDCPLSRLQLFPLTHCCGPGLRPISQEDKATQTLSPASPSQGVMLPCGVTEEPQRLFYGNAGYRLPLPASFPAGSPLGEQPPEGQFLQHRAEVQIARKLQCIADQFHRLHTQQHQQNRDRAWWQVFLFLQNLALNRQENREGVGPW
Protein: Gap junction alpha-5 protein
UniProt accession: Q01231
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Cxn-40, Gja5
Length: 358 residues
Disorder content (fraction disordered): 0.29329608938547486
Curated region start positions: 251, 251, 251, 251, 251, 251
Curated region end positions: 355, 355, 355, 355, 355, 355
Curated region terms: disorder, protein binding, disorder, protein binding, disorder, protein binding
Domain/feature annotations: Gap junction channel protein cysteine-rich domain, Connexin, Connexin 40 C-terminal domain
Cross-references: PDB:2K7M
Sequence:
MGDWSFLGEFLEEVHKHSTVIGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKQKLRDAEKAKEAHRTGAYEYPVAEKAELSCWKEVDGKIVLQGTLLNTYVCTILIRTTMEVAFIVGQYLLYGIFLDTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMMAVAGLSLFLSLAELYHLGWKKIRQRFGKSRQGVDKHQLPGPPTSLVQSLTPPPDFNQCLKNSSGEKFFSDFSNNMGSRKNPDALATGEVPNQEQIPGEGFIHMHYSQKPEYASGASAGHRLPQGYHSDKRRLSKASSKARSDDLSV
Protein: Superoxide dismutase [Cu-Zn]
UniProt accession: P00441
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SOD1
Length: 154 residues
Disorder content (fraction disordered): 0.16883116883116883
Dataset labels: NDDs-related proteins, Age-related disorders proteins
Curated region start positions: 69, 127, 127, 69, 69, 127
Curated region end positions: 78, 142, 142, 78, 78, 142
Curated region terms: disorder, disorder, order, order, disorder to order, disorder to order
Domain/feature annotations: Superoxide dismutase, copper/zinc binding domain, Copper/zinc superoxide dismutase (SODC)
Cross-references: DisProt:DP00652r005, DisProt:DP00652r006, PDB:1UXM, PDB:3GZQ
Sequence:
MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
Protein: Peroxisomal fatty acid beta-oxidation multifunctional protein MFP2
UniProt accession: Q9ZPI5
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At3g06860, F17A9.1, MFP2
Length: 725 residues
Disorder content (fraction disordered): 0.04551724137931035
Curated region start positions: 71, 576
Curated region end positions: 82, 596
Curated region terms: disorder, disorder
Domain/feature annotations: 2-enoyl-CoA Hydratase; Chain A, domain 1, NAD(P)-binding Rossmann-like Domain, 1.10.1040.50, Enoyl-CoA hydratase/isomerase, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Sequence:
MDSRTKGKTVMEVGGDGVAVITLINPPVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERTYKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEFFKPCAFLAERGSKGVLLSAPVKQASSRL
Protein: Fermitin family homolog 1
UniProt accession: P59113
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Fermt1, Kind1, Urp1
Length: 677 residues
Disorder content (fraction disordered): 0.17725258493353027
Curated region start positions: 141, 1
Curated region end positions: 249, 11
Curated region terms: disorder, disorder
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, FERM central domain, FERM central domain, Kindlin-2 N-terminal domain
Cross-references: PDB:2KMC
Sequence:
MLSSGDLTSASWELVVRVDHANGEQQTEITLRVSGDLHIGGVMLKLVEQMNIAQDWSDYALWWEQKRCWLLKTHWTLDKCGVQADANLLFTPQHKMLRLRLPNAKTVRLRVSFSAVVFKAVADICKVLNIRRPEELSLLKPSSDYCKKKKKKEKNSKEPVIEDILNLESSSTSSGSPVSPGLYSKTMTPTYDPINGTPALSTMTWFGDSPLTEQNCSVLAFSQPPPSPDVLADMFQPRSLVDKAKMNAGWLDSSRSLMEQSIQEDEQLQLRFKYYTFFDLNPKYDAVRINQLYEQARWAVLLEEIDCTEEEMLIFAALQYHISKLSQCAEIQDFATKSEVDEVEAALSSLEVTLEGGKADNTLEDITDIPKLADYLKLFRPKKLMLKACKQYWFVFKDTSIAYFKNKELEQGEPIEKLNLRGCEIVPDVNVSGRKFGIKLLIPVADGMNEVYLRCDHEDQYARWMAACILASKGKTMADSSYQPEVISILSFLKMKNRNSSPLVASSLENMDMNPECLVSPCCAKKHKSKQLAARILEAHHNVAQMPLVEAKLQFIQAWQSLPEFGLTYYLVRFKGSKKDDILGVAYNRLIRIDAVTGIPVTTWRFANMKQWNVNWEIRQVAIEFDQNVSIAFTCLSADCKIVHEYIGGYIFLSTRSKDQNETLDEDLFHKLTGGQD