Protein: Core protein precursor
UniProt accession: Q9WIK7
Organism: Hepacivirus C
Taxonomy: Viruses, Riboviria, Orthornavirae, Kitrinoviricota, Flasuviricetes, Amarillovirales, Flaviviridae, Hepacivirus
Length: 3012 residues
Disorder content (fraction disordered): 0.011288180610889776
Dataset labels: Viral proteins
Curated region start positions: 2282, 2282, 2282, 2282, 2282, 2287
Curated region end positions: 2301, 2315, 2301, 2301, 2301, 2291
Curated region terms: disorder, disorder, protein binding, disorder, viral genome replication, viral genome replication
Domain/feature annotations: Viral RNA dependent RNA polymerase, Hepatitis C virus non-structural protein NS4b, Hepatitis C virus non-structural protein NS4a, Hepatitis C virus non-structural 5a protein membrane anchor, Hepatitis C virus non-structural protein NS2, Hepatitis C virus envelope glycoprotein E1, Hepatitis C virus core protein, Hepatitis C virus capsid protein, Hepatitis C virus non-structural protein E2/NS1, Hepatitis C virus NS3 protease, Flavivirus DEAD domain, Hepatitis C virus non-structural 5a zinc finger domain, Hepatitis C virus non-structural 5a domain 1b, HCV NS5a protein C-terminal region, NS3 RNA helicase, C-terminal helical domain
Cross-references: BMRB:19059, PDB:2M5L
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRAWAQPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPTDPRRRSRNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTIPASAYEVRNVSGVYHVTNDCSNSSIVYETADMIMHTPGCVPCVREDNSSRCWVALTPTLAARNGSVPTTAIRRHVDLLVGAAAFCSAMYVGDFCGSVFLVSQLFTLSPRRHETVQECNCSIYPGHVTGHRMAWDMMMNWSPTTALVVSQLLRIPQAVVDMVAGAHWGVLAGLAYYSMVGNWAKLLIVMLLFAGVDGGGPTRTIGGSQAQAASGLVSMFSVGPSQKIQLINTNGSWHINRTALNCNDSLNTGFLAALFYAHKFNSSGCPERMASCRPIDRFAQGWGPITYAEPGSLDQRPYCWHYAPQPCGIVPASEVCGPVYCFTPSPVVVGTTDRSGVPTYRWGDNETDVLLLNNTRPPQGNWFGCTWMNTTGFTKTCGGPPCNIGGLGNNTLICPTDCFRKHSEATYTKCGSGPWLTPRCIVDYPYRLWHYPCTVNFTIFKVRMYVGGIEHRLSAACNWTRGERCNLEDRDRSELSPLLLSTTEWQILPCSFTTLPAPSTGLIHLHQNIVDVQYLYGIGSVLVSFAIKWEYILLLFLLLADARVCACLWMMLLIAQAEAALENLVVLNAASLAGAHGILSFLVFFCAAWYIKGRLVPGAAYALYSVWPLLLLLLALPPRAYAMDREMAASCGGAVFVGLVLLTLSPYYKVFLAKLIWWLQYFITRAEAHLQVWIPPLNVRGGRDAIILLTCAVHPELIFDITKLLLAILGPLMVLQAGIIRAPYFVRAQGLIRACMLVRKVAGGHYVQMAFMKLAALTGTYVYDHLTPLRDWAHAGLRDLAVAVEPVVFSDMETKIITWGADTAACGDIILGLPVSARRGKEILLGPADSLEGQGWRLLAPITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVYHGAGSKTLAGPKGPITQMYTNVDQDLVGWPAPSGARSLTPCTCGSSDLYLVSRHADVIPVRRRGDSRGSLLSPRPVSYLKGSSGGPLLCPSGHVVGIFRAAVCTRGVAKAVDFVPVESMETTTRSPVFTDNSSPPAVPQTFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLSFGAYMSKAHGVDPSIRTGVRTITTGAPITYSTYGKFLADGGCSGGAYDIIICDECHSTDSTSILGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSNTGEIPFYGKAIPIETIRGGRHLIFCHSKKKCDELAAQLSGLGINAVAYYRGLDVSVIPTSGDVVVVATDALMTGFTGDFDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRRGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLYRLGAVQNEVTLTHPVTKYIMACMSADLEVVTSTWVLVGGVLAALAAYCLTTGSVVIVGRIILSGKPAIVPDRGVLYREFDEMEECASHLPYIEQGMQLAEQFKQKALGLLQTATKQAEAAAPVVESKWRALEAFWAKHMWSFISGIQYLAGLSTLPGNPAIASLMAFTASVTSPLTTQHTLLFNILGGWVAAQLAPPSAASAFVGAGIAGAAVGSIGLGKVLVDILAGYGAGVAGALVAFKVMSGEMPSTEDLVNLLPAILSPGALVVGVVCAAILRRHVGPGEGAVQWMNRLIAFASRGNHVSPTHYVPESDAAARVTQILSSLTITQLLKRLHQWINEDCSTPCSGSWLRDVWDWICTVLTDFKTWLQSKLLPRLPGVPFFSCQRGYKGVWRGDGIMQTTCPCGAQITGHVKNGSMRIVGPRTCSNTWHGTFPINAYTTGPCTPSPAPNYFRALWRVAAEEYVEVTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFQVGLNQYLVGSQLPCEPEPGVTVLTSMLTDPSHITAETAKRRLDRGSPPSLASSSASQLSAPSLKATCTTRHDSPDADLIEANLLWRQEMGGNITRVESENKVVILDSFDPLRAEEDEREISVPAEILRRSRKFPRAMPIWARPDYNPPLLESWKDPDYVPPVVHGCPLPPAKAPPVPPPRRKRTVVLTESTVSSALAELATKTFGSSESSAVDSGTATAPPGQPSDGGDTGSDAESCSSMPPLEGEPGDPDLSDGSWSTVSEEASEDVVCCSMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSASQRQKKVTFDRLQVLDDHYWDVLKEMKAKASTVKARLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAINHINSVWEDLLEDTETPIDTTIMAKNEVFCVQPEKGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPGQRVEFLVKAWSSKKNPMGFAYDTRCFDSTVTENDIRVGESIYQCCDLAPEARQAIRSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVCGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMVLMIHFFSILLAQEQLEKALDCQIYGACYSIEPLDLPQIIQRLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVWRHRARSVRAKLLSRGGRAATCGKYLFNWAVRTKLKLTPIPAASRLDLSGWFVAGYSGGDIYHSLSPARPRWFMWCLLLLSVGVGIYLLPNR