LiteFold/DisProt huggingface dataset:
Protein: F-actin-capping protein subunit beta
UniProt accession: P13021
Organism: Dictyostelium discoideum
Taxonomy: Eukaryota, Amoebozoa, Evosea, Eumycetozoa, Dictyostelia, Dictyosteliales, Dictyosteliaceae, Dictyostelium
Gene names: DDB_G0267374, abpE, acpA
Length: 272 residues
Disorder content (fraction disordered): 0.08088235294117647
Curated region start positions: 253, 253, 251, 251, 253
Curated region end positions: 272, 272, 272, 272, 272
Curated region terms: disorder, protein binding, disorder, lipid binding, lipid binding
Domain/feature annotations: F-actin capping protein, beta subunit
Cross-references: PDB:4AKR
Sequence:
MTEKQLSCCLDLMRRLPPSQIEDNLAGLLDLVPDLTEDLLSSIDQPLKVAYDAVSKKDYLLCDYNRDADSYRSPWSNKYDPPLSGACYPSSKLRDIEVQANEIFEIYLNLYFEGGVSSVYCWDLDDNFAAVVLMKKTQDQSKKGQPMRGTWDSIHVVEVKLGKKDKAVYKLTSTVMLSIETDNDNTGKVNLAGSLTRQDEKEYTFNEVDTHCVNIGKMVEDMESKLRQTLETIYFGKTKEVVNTLRNATGNSELEKRKNLSNQIGSAIGNRG
Protein: Heat shock protein 15
UniProt accession: P0ACG8
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3363, b3400, hslR, yrfH
Length: 133 residues
Disorder content (fraction disordered): 0.17293233082706766
Curated region start positions: 111
Curated region end positions: 133
Curated region terms: disorder
Domain/feature annotations: S4 domain
Cross-references: PDB:1DM9
Sequence:
MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSKPSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALARKLNALTMPHPDRRPDKKERRDLLRFKHGDSE
Protein: Protein Z-dependent protease inhibitor
UniProt accession: Q9UK55
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SERPINA10, UNQ707/PRO1358, ZPI
Length: 444 residues
Disorder content (fraction disordered): 0.08783783783783784
Dataset labels: Extracellular matrix proteins
Curated region start positions: 22, 22
Curated region end positions: 59, 60
Curated region terms: disorder, disorder
Domain/feature annotations: Serpin (serine protease inhibitor)
Cross-references: PDB:3F1S, PDB:3H5C
Sequence:
MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL
Protein: Coagulation factor X
UniProt accession: P00742
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: F10
Length: 488 residues
Disorder content (fraction disordered): 0.07581967213114754
Dataset labels: Extracellular matrix proteins
Curated region start positions: 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 90, 99, 106, 100
Curated region end positions: 120, 120, 126, 120, 120, 120, 120, 120, 120, 120, 120, 120, 120, 116, 116, 105
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder to order, protein binding, protein binding
Domain/feature annotations: EGF-like domain, Trypsin, Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain, Coagulation Factor Xa inhibitory site
Cross-references: PDB:1EZQ, PDB:1F0R, PDB:1F0S, PDB:1FAX, PDB:1FJS, PDB:1HCG, PDB:1LPG, PDB:1LPK, PDB:1LPZ, PDB:1LQD, PDB:1NFU, PDB:1NFW, PDB:1NFX, PDB:1NFY, PDB:1P0S, PDB:2BMG, PDB:2BOH, PDB:2BQ6, PDB:2BQ7, PDB:2BQW, PDB:2H9E, PDB:2J94, PDB:2J95, PDB:2P3F, PDB:2Q1J, PDB:4Y76, PDB:4Y79, PDB:5JQY, PDB:5JZ8, PDB:5JZU, PDB:6RK9
Sequence:
MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEETCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKNCELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERRKRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPEVITSSPLK
Protein: Speckle-type POZ protein
UniProt accession: O43791
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SPOP
Length: 374 residues
Disorder content (fraction disordered): 0.0748663101604278
Dataset labels: Cancer-related proteins, NDDs-related proteins, Condensates-related proteins
Curated region start positions: 357, 169, 169, 361, 361, 361
Curated region end positions: 374, 178, 178, 374, 374, 374
Curated region terms: disorder, flexible linker, disorder, localization, molecular function regulator, molecular function inhibitor activity
Domain/feature annotations: BTB/POZ domain, MATH domain, BPM/SPOP, BACK domain
Cross-references: PDB:4J8Z
Sequence:
MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
Protein: Protein AMBP
UniProt accession: P02760
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AMBP, HCP, ITIL
Length: 352 residues
Disorder content (fraction disordered): 0.13920454545454544
Dataset labels: Extracellular matrix proteins
Curated region start positions: 340, 206, 191, 213
Curated region end positions: 352, 229, 202, 217
Curated region terms: disorder, disorder, disorder, carbohydrate binding
Domain/feature annotations: Kunitz/Bovine pancreatic trypsin inhibitor domain, Kunitz/Bovine pancreatic trypsin inhibitor domain, Lipocalin / cytosolic fatty-acid binding protein family
Cross-references: PDB:1BIK, PDB:3QKG
Sequence:
MRSLGALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIMDRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMESYVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEPEPILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGDEELLRFSN
Protein: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
UniProt accession: P60484
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MMAC1, PTEN, TEP1
Length: 403 residues
Disorder content (fraction disordered): 0.18610421836228289
Dataset labels: Cancer-related proteins, Autophagy-related proteins, NDDs-related proteins
Curated region start positions: 354, 353, 353, 378, 380, 381, 286, 366, 366, 366
Curated region end positions: 403, 403, 403, 382, 384, 385, 309, 385, 385, 385
Curated region terms: disorder, disorder, molecular function regulator, phosphorylation display site, phosphorylation display site, phosphorylation display site, disorder, self-inhibition, protein binding, self-assembly
Domain/feature annotations: C2 domain of PTEN tumour-suppressor protein, Polymorphic toxin system, DSP-PTPase phosphatase
Sequence:
MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHLDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKIYSSNSGPTRREDKFMYFEFPQPLPVCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
Protein: Cystatin-C
UniProt accession: P01034
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CST3
Length: 146 residues
Disorder content (fraction disordered): 0.07534246575342465
Dataset labels: Extracellular matrix proteins, Age-related disorders proteins
Curated region start positions: 27, 27, 35, 27
Curated region end positions: 37, 37, 39, 37
Curated region terms: disorder, disorder, limited proteolysis display site, molecular function inhibitor activity
Domain/feature annotations: Cystatin domain
Cross-references: BMRB:34399, PDB:6ROA, PDB:6RPV
Sequence:
MAGPLRAPLLLLAILAVALAVSPAAGSSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA
Protein: Ras-related C3 botulinum toxin substrate 1
UniProt accession: P63000
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MIG5, RAC1, TC25
Length: 192 residues
Disorder content (fraction disordered): 0.07291666666666667
Dataset labels: Cancer-related proteins, Autophagy-related proteins, NDDs-related proteins
Curated region start positions: 182, 179, 179, 178, 178, 184, 178, 184, 184
Curated region end positions: 192, 192, 192, 188, 188, 188, 182, 188, 188
Curated region terms: disorder, disorder, disorder, protein binding, molecular function regulator, protein binding, protein binding, localization, molecular function regulator
Domain/feature annotations: Ras family
Cross-references: PDB:1E96, PDB:1I4D, PDB:1I4L, PDB:1I4T, PDB:5FI0
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
Protein: Prothrombin
UniProt accession: P00734
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: F2
Length: 622 residues
Disorder content (fraction disordered): 0.1045016077170418
Dataset labels: Extracellular matrix proteins
Curated region start positions: 187, 298, 298, 187, 90, 187, 187, 301, 312
Curated region end positions: 211, 316, 316, 211, 110, 211, 211, 316, 316
Curated region terms: disorder, disorder, flexible linker, flexible linker, disorder, flexible linker, disorder, disorder, limited proteolysis display site
Domain/feature annotations: Kringle domain, Kringle domain, Trypsin, Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain, Thrombin light chain
Cross-references: PDB:4HZH, PDB:4NZQ, PDB:4O03
Sequence:
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
Protein: RAC-alpha serine/threonine-protein kinase
UniProt accession: P31749
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AKT1, PKB, RAC
Length: 480 residues
Disorder content (fraction disordered): 0.06458333333333334
Dataset labels: Cancer-related proteins
Curated region start positions: 114, 114
Curated region end positions: 144, 144
Curated region terms: disorder, flexible linker
Domain/feature annotations: Protein kinase domain, PH domain, Protein kinase C terminal domain
Cross-references: PDB:3O96
Sequence:
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
Protein: Matrilysin
UniProt accession: P09237
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MMP7, MPSL1, PUMP1
Length: 267 residues
Disorder content (fraction disordered): 0.16853932584269662
Dataset labels: Extracellular matrix proteins
Curated region start positions: 18, 90, 256, 90, 21
Curated region end positions: 28, 99, 267, 99, 40
Curated region terms: disorder, disorder, disorder, disorder to order, disorder
Domain/feature annotations: Matrixin, Putative peptidoglycan binding domain
Cross-references: PDB:2MZE, PDB:2MZH, PDB:2MZI
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
Protein: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
UniProt accession: G5EFZ1
Organism: Caenorhabditis elegans
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Nematoda, Chromadorea, Rhabditida, Rhabditina, Rhabditomorpha, Rhabditoidea, Rhabditidae, Peloderinae, Caenorhabditis
Gene names: F57B10.3, ipgm-1
Length: 539 residues
Disorder content (fraction disordered): 0.07235621521335807
Curated region start positions: 1, 520
Curated region end positions: 19, 539
Curated region terms: disorder, disorder
Domain/feature annotations: Metalloenzyme superfamily, Metalloenzyme superfamily, BPG-independent PGAM N-terminus (iPGM_N)
Cross-references: PDB:5KGL, PDB:5KGM, PDB:5KGN
Sequence:
MFVALGAQIYRQYFGRRGMAMANNSSVANKVCLIVIDGWGVSEDPYGNAILNAQTPVMDKLCSGNWAQIEAHGLHVGLPEGLMGNSEVGHLNIGAGRVIYQDIVRINLAVKNNKFVTNESLVDACDRAKNGNGRLHLAGLVSDGGVHSHIDHMFALVKAIKELGVPELYLHFYGDGRDTSPNSGVGFLEQTLEFLEKTTGYGKLATVVGRYYAMDRDNRWERINVAYEAMIGGVGETSDEAGVVEVVRKRYAADETDEFLKPIILQGEKGRVQNDDTIIFFDYRADRMREISAAMGMDRYKDCNSKLAHPSNLQVYGMTQYKAEFPFKSLFPPASNKNVLAEWLAEQKVSQFHCAETEKYAHVTFFFNGGLEKQFEGEERCLVPSPKVATYDLQPEMSAAGVADKMIEQLEAGTHPFIMCNFAPPDMVGHTGVYEAAVKACEATDIAIGRIYEATQKHGYSLMVTADHGNAEKMKAPDGGKHTAHTCYRVPLTLSHPGFKFVDPADRHPALCDVAPTVLAIMGLPQPAEMTGVSIVQKI
Protein: Serpin A12
UniProt accession: Q8IW75
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SERPINA12
Length: 414 residues
Disorder content (fraction disordered): 0.026570048309178744
Dataset labels: Extracellular matrix proteins
Curated region start positions: 367, 376, 367
Curated region end positions: 377, 380, 377
Curated region terms: disorder, limited proteolysis display site, molecular function inhibitor activity
Domain/feature annotations: Serpin (serine protease inhibitor)
Cross-references: PDB:4IF8
Sequence:
MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK
Protein: Serpin B5
UniProt accession: P36952
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PI5, SERPINB5
Length: 375 residues
Disorder content (fraction disordered): 0.032
Dataset labels: Extracellular matrix proteins
Curated region start positions: 332, 334
Curated region end positions: 343, 338
Curated region terms: disorder, limited proteolysis display site
Domain/feature annotations: Serpin (serine protease inhibitor)
Cross-references: PDB:1WZ9, PDB:1XU8
Sequence:
MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDELNADHPFIYIIRHNKTRNIIFFGKFCSP
Protein: Pro-neuregulin-1, membrane-bound isoform
UniProt accession: Q02297
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GGF, HGL, HRGA, NDF, NRG1, SMDF
Length: 640 residues
Disorder content (fraction disordered): 0.025
Dataset labels: Autophagy-related proteins, Cancer-related proteins, Extracellular matrix proteins
Curated region start positions: 226, 229
Curated region end positions: 239, 241
Curated region terms: disorder, disorder
Domain/feature annotations: EGF-like domain, Neuregulin intracellular region, Immunoglobulin I-set domain
Cross-references: PDB:1HAE, PDB:1HAF, PDB:1HRE, PDB:1HRF
Sequence:
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQDPIAV
Protein: Collagen alpha-1(XVII) chain
UniProt accession: Q9UMD9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BP180, BPAG2, COL17A1
Length: 1497 residues
Disorder content (fraction disordered): 0.3032732130928524
Dataset labels: Extracellular matrix proteins
Curated region start positions: 2, 2, 2
Curated region end positions: 455, 455, 455
Curated region terms: disorder, disorder to order, lipid binding
Domain/feature annotations: Collagen triple helix repeat (20 copies), Collagen triple helix repeat (20 copies), Collagen triple helix repeat (20 copies)
Sequence:
MDVTKKNKRDGTEVTERIVTETVTTRLTSLPPKGGTSNGYAKTASLGGGSRLEKQSLTHGSSGYINSTGSTRGHASTSSYRRAHSPASTLPNSPGSTFERKTHVTRHAYEGSSSGNSSPEYPRKEFASSSTRGRSQTRESEIRVRLQSASPSTRWTELDDVKRLLKGSRSASVSPTRNSSNTLPIPKKGTVETKIVTASSQSVSGTYDATILDANLPSHVWSSTLPAGSSMGTYHNNMTTQSSSLLNTNAYSAGSVFGVPNNMASCSPTLHPGLSTSSSVFGMQNNLAPSLTTLSHGTTTTSTAYGVKKNMPQSPAAVNTGVSTSAACTTSVQSDDLLHKDCKFLILEKDNTPAKKEMELLIMTKDSGKVFTASPASIAATSFSEDTLKKEKQAAYNADSGLKAEANGDLKTVSTKGKTTTADIHSYGSSGGGGSGGGGGVGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLLLLGLLFGLIALAEEVRKLKARVDELERIRRSILPYGDSMDRIEKDRLQGMAPAAGADLDKIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQYLMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKGDQVYAGRRRRRSIAVKP
Protein: Roundabout homolog 3
UniProt accession: Q96MS0
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ROBO3
Length: 1386 residues
Disorder content (fraction disordered): 0.010101010101010102
Curated region start positions: 654, 654
Curated region end positions: 667, 667
Curated region terms: disorder, flexible linker
Domain/feature annotations: Fibronectin type III domain, Fibronectin type III domain, Fibronectin type III domain, Immunoglobulin I-set domain, Immunoglobulin I-set domain, Immunoglobulin I-set domain, Immunoglobulin domain, Immunoglobulin domain
Sequence:
MLRYLLKTLLQMNLFADSLAGDISNSSELLLGFNSSLAALNHTLLPPGDPSLNGSRVGPEDAMPRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGALFFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPAVLECVPPRGHPEPSVSWRKDGARLKEEEGRITIRGGKLMMSHTLKSDAGMYVCVASNMAGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKEDGELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAAPGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMREDWGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTGAAVTSYVIEAFSPAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPVSEPVRTQDSSPSRPVEDPWRGQQGLAEVAVRLQEPIVLGPRTLQVSWTVDGPVQLVQGFRVSWRVAGPEGGSWTMLDLQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESLSVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQIWCLGNESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPSPPDLEPGLEVGAGLAVRLARVLREPAFLAGSGAACGALLLGLCAALYWRRKQRKELSHYTASFAYTPAVSFPHSEGLSGASSRPPMGLGPAPYSWLADSWPHPSRSPSAQEPRGSCCPSNPDPDDRYYNEAGISLYLAQTARGTAAPGEGPVYSTIDPAGEELQTFHGGFPQHPSGDLGPWSQYAPPEWSQGDSGAKGGKVKLLGKPVQMPSLNWPEALPPPPPSCELSCLEGPEEELEGSSEPEEWCPPMPERSHLTEPSSSGGCLVTPSRRETPSPTPSYGQQSTATLTPSPPDPPQPPTDMPHLHQMPRRVPLGPSSPLSVSQPMLGIREARPAGLGAGPAASPHLSPSPAPSTASSAPGRTWQGNGEMTPPLQGPRARFRKKPKALPYRRENSPGDLPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKAVQAVPLAAQRVLHPDEEAWLPYSRPSFLSRGQGTSTCSTAGSNSSRGSSSSRGSRGPGRSRSRSQSRSQSQRPGQKRREEPR