LiteFold/DisProt huggingface dataset:
Protein: Estrogen receptor beta
UniProt accession: Q92731
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ESR2, ESTRB, NR3A2
Length: 530 residues
Disorder content (fraction disordered): 0.19433962264150945
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 1
Curated region end positions: 103, 103
Curated region terms: disorder, disorder
Domain/feature annotations: Erythroid Transcription Factor GATA-1, subunit A, Retinoid X Receptor, Ligand-binding domain of nuclear hormone receptor, Double treble clef zinc finger, C4 type, Estrogen receptor beta
Sequence:
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPSNVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVNRETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
Protein: Transcription initiation factor TFIID subunit 1
UniProt accession: P51123
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG17603, TAF250, Taf1
Length: 2129 residues
Disorder content (fraction disordered): 0.04133395960544857
Curated region start positions: 11, 11, 11, 1840
Curated region end positions: 77, 77, 77, 1860
Curated region terms: disorder, disorder to order, protein binding, disorder
Domain/feature annotations: TAFII-230 TBP-binding domain, Bromodomain-like, Bromodomain-like, Bromodomain, Bromodomain, TATA box-binding protein binding, Protein of unknown function (DUF3591), Zinc knuckle
Cross-references: PDB:1TBA
Sequence:
MEMESDNSDDEGSIGNGLDLTGILFGNIDSEGRLLQDDDGEGRGGTGFDAELRENIGSLSKLGLDSMLLEVIDLKEAEPPSDDEEEEDARPSAVSASEGMSAFDALKAGVKREDGAVKAQDDAIDYSDITELSEDCPRTPPEETSTYDDLEDAIPASKVEAKLTKDDKELMPPPSAPMRSGSGGGIEEPAKSNDASSPSDDSKSTDSKDADRKLDTPLADILPSKYQNVDVRELFPDFRPQKVLRFSRLFGPGKPTSLPQIWRHVRKRRRKRNQSRDQKTTNTGGSDSPSDTEEPRKRGFSLHYAAEPTPAECMSDDEDKLLGDFNSEDVRPEGPDNGENSDQKPKVADWRFGPAQIWYDMLEVPDSGEGFNYGFKTKAASTSSQPQLKDERRVKSPEDDVEDPSIADDAFLMVSQLHWEDDVVWDGNDIKAKVLQKLNSKTNAAGWLPSSGSRTAGAFSQPGKPSMPVGSGSSKQGSGASSKKAQQNAQAKPAEAPDDTWYSLFPVENEELIYYKWEDEVIWDAQQVSKVPKPKVLTLDPNDENIILGIPDDIDPSKINKSTGPPPKIKIPHPHVKKSKILLGKAGVINVLAEDTPPPPPKSPDRDPFNISNDTYYTPKTEPTLRLKVGGNLIQHSTPVVELRAPFVPTHMGPMKLRAFHRPPLKKYSHGPMAQSIPHPVFPLLKTIAKKAKQREVERIASGGGDVFFMRNPEDLSGRDGDIVLAEFCEEHPPLINQVGMCSKIKNYYKRKAEKDSGPQDFVYGEVAFAHTSPFLGILHPGQCIQAIENNMYRAPIYPHKMAHNDFLVIRTRNNYWIRSVNSIYTVGQECPLYEVPGPNSKRANNFTRDFLQVFIYRLFWKSRDNPRRIRMDDIKQAFPAHSESSIRKRLKQCADFKRTGMDSNWWVIKPEFRLPSEEEIRAMVSPEQCCAYFSMIAAEQRLKDAGYGEKFLFAPQEDDDEEAQLKLDDEVKVAPWNTTRAYIQAMRGKCLLQLSGPADPTGCGEGFSYVRVPNKPTQTKEEQESQPKRSVTGTDADLRRLPLQRAKELLRQFKVPEEEIKKLSRWEVIDVVRTLSTEKAKAGEEGMDKFSRGNRFSIAEHQERYKEECQRIFDLQNRVLASSEVLSTDEAESSASEESDLEELGKNLENMLSNKKTSTQLSREREELERQELLRQLDEEHGGPSGSGGAKGAKGKDDPGQQMLATNNQGRILRITRTFRGNDGKEYTRVETVRRQPVIDAYIKIRTTKDEQFIKQFATLDEQQKEEMKREKRRIQEQLRRIKRNQERERLAQLAQNQKLQPGGMPTSLGDPKSSGGHSHKERDSGYKEVSPSRKKFKLKPDLKLKCGACGQVGHMRTNKACPLYSGMQSSLSQSNPSLADDFDEQSEKEMTMDDDDLVNVDGTKVTLSSKILKRHGGDDGKRRSGSSSGFTLKVPRDAMGKKKRRVGGDLHCDYLQRHNKTANRRRTDPVVVLSSILEIIHNELRSMPDVSPFLFPVSAKKVPDYYRVVTKPMDLQTMREYIRQRRYTSREMFLEDLKQIVDNSLIYNGPQSAYTLAAQRMFSSCFELLAEREDKLMRLEKAINPLLDDDDQVALSFIFDKLHSQIKQLPESWPFLKPVNKKQVKDYYTVIKRPMDLETIGKNIEAHRYHSRAEYLADIELIATNCEQYNGSDTRYTKFSKKILEYAQTQLIEFSEHCGQLENNIAKTQERARENAPEFDEAWGNDDYNFDRGSRASSPGDDYIDVEGHGGHASSSNSIHRSMGAEAGSSHTAPAVRKPAPPGPGEVKRGRGRPRKQRDPVEEVKSQNPVKRGRGRPRKDSLASNMSHTQAYFLDEDLQCSTDDEDDDEEEDFQEVSEDENNAASILDQGERINAPADAMDGMFDPKNIKTEIDLEAHQMAEEPIGEDDSQQVAEAMVQLSGVGGYYAQQQQDESMDVDPNYDPSDFLAMHKQRQSLGEPSSLQGAFTNFLSHEQDDNGPYNPAEASTSAASGADLGMDASMAMQMAPEMPVNTMNNGMGIDDDLDISESDEEDDGSRVRIKKEVFDDGDYALQHQQMGQAASQSQIYMVDSSNEPTTLDYQQPPQLDFQQVQEMEQLQHQVMPPMQSEQLQQQQTPQGDNDYAWTF
Protein: Eukaryotic initiation factor 4F subunit p150
UniProt accession: P39935
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: TIF4631, YGR162W
Length: 952 residues
Disorder content (fraction disordered): 0.3644957983193277
Curated region start positions: 393, 393, 393, 393, 393, 393, 1, 187, 1, 39, 100, 35, 35, 35, 135, 200, 1, 93, 1, 1, 1, 1
Curated region end positions: 490, 490, 490, 490, 490, 490, 249, 239, 239, 45, 106, 49, 49, 49, 160, 234, 243, 114, 243, 82, 82, 82
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder to order, protein binding, disorder, order, disorder, protein binding, protein binding, protein binding, disorder to order, order, protein binding, protein binding, molecular condensate scaffold activity, molecular condensate scaffold activity, molecular condensate scaffold activity, RNA binding, RNA binding, RNA binding
Domain/feature annotations: 1.25.40.180, eIF4G, eIF4E-binding domain, MIF4G domain, Eukaryotic translation initiation factor 4G1
Cross-references: PDB:1RF8, PDB:6Z29
Sequence:
MTDETAHPTQSASKQESAALKQTGDDQQESQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGGKFGPNRYNNRGNYNGGGSFRGGHMGANSSNVPWTGYYNNYPVYYQPQQMAAAGSAPANPIPVEEKSPVPTKIEITTKSGEHLDLKEQHKAKLQSQERSTVSPQPESKLKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKEQLEGSSGNNNIPMKTTPENVEEKGSDKPEVTEKTKPAEEKSAEPEVKQETPAEEGEQGEKGQIKEESTPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEAEVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKDATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASKIVIPPGMGRGNRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRERGSYRNEEKREDDKPKEEVAPLVPSANRWVPKFKSKKTEKKLAPDGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGTPLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTAKISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLKNNSRSNSRRTNNSSNRHSFRRDAPPASKDSFITTRTYSQRNSQRAPPPKEEPAAPTSTATNMFSALMGESDDEE
Protein: General control protein GCN4
UniProt accession: P03069
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: AAS101, AAS3, ARG9, GCN4, YEL009C
Length: 281 residues
Disorder content (fraction disordered): 0.4768683274021353
Dataset labels: Condensates-related proteins
Curated region start positions: 101, 117, 1, 101, 101, 101
Curated region end positions: 134, 127, 100, 134, 134, 134
Curated region terms: disorder, disorder to order, disorder, mediator complex binding, TFIID-class transcription factor complex binding, mediator complex binding
Domain/feature annotations: Classic Zinc Finger, Basic region leucine zipper
Cross-references: PDB:2LPB
Sequence:
MSEYQPSLFALNPMGFSPLDGSKSTNENVSASTSTAKPMVGQLIFDKFIKTEEDPIIKQDTPSNLDFDFALPQTATAPDAKTVLPIPELDDAVVESFFSSSTDSTPMFEYENLEDNSKEWTSLFDNDIPVTTDDVSLADKAIESTEEVSLVPSNLEVSTTSFLPTPVLEDAKLTQTRKVKKPNSVVKKSHHVGKDDESRLDHLGVVAYNRKQRSIPLSPIVPESSDPAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGER
Protein: Protein max
UniProt accession: P61244
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BHLHD4, MAX
Length: 160 residues
Disorder content (fraction disordered): 0.49375
Dataset labels: Cancer-related proteins
Curated region start positions: 1, 1, 1, 103, 103, 103, 1, 1, 9, 1, 1, 1, 103, 1
Curated region end positions: 14, 21, 21, 160, 160, 160, 21, 5, 13, 21, 21, 21, 160, 21
Curated region terms: disorder, disorder, protein binding, disorder, protein binding, Myc-Max complex, Myc-Max complex, phosphorylation display site, phosphorylation display site, self-regulatory activity, regulation of DNA binding, flexible N-terminal tail, flexible C-terminal tail, self-assembly
Domain/feature annotations: Helix-loop-helix DNA-binding domain, Helix-loop-helix DNA-binding domain
Cross-references: BMRB:51505
Sequence:
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS
Protein: Cellular tumor antigen p53
UniProt accession: P04637
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: P53, TP53
Length: 393 residues
Disorder content (fraction disordered): 0.3765903307888041
Dataset labels: Autophagy-related proteins, Cancer-related proteins, Condensates-related proteins
Curated region start positions: 1, 1, 291, 1, 20, 20, 37, 37, 17, 15, 367, 367, 380, 367, 367, 47, 41, 15, 17, 1, 1, 1, 14, 369, 359, 366, 366, 366, 385, 372, 375, 367, 367, 376, 372, 365, 368, 379, 1, 1, 14, 42, 42, 1, 1, 1, 1, 20, 56, 1, 1, 14, 38, 1, 1, 361, 361, 19, 367, 1, 1, 1, 1
Curated region end positions: 12, 93, 312, 93, 73, 73, 57, 57, 29, 29, 386, 386, 384, 386, 386, 58, 62, 29, 27, 93, 93, 93, 60, 377, 367, 386, 386, 386, 393, 389, 385, 388, 388, 386, 389, 375, 372, 385, 39, 39, 19, 56, 56, 73, 73, 73, 73, 46, 70, 61, 61, 28, 61, 61, 61, 393, 393, 26, 388, 93, 93, 93, 93
Curated region terms: disorder, disorder, disorder, disorder, protein binding, molecular function activator activity, disorder to order, protein binding, disorder to order, protein binding, protein binding, protein binding, acetylation display site, molecular function activator activity, disorder to order, protein binding, disorder to order, protein binding, disorder to order, protein binding, protein binding, protein binding, disorder to order, protein binding, protein binding, protein binding, disorder to order, protein binding, 14-3-3 protein binding, protein binding, disorder to order, protein binding, disorder to order, protein binding, protein binding, protein binding, methylation display site, protein binding, protein binding, disorder to order, phosphorylation display site, disorder to order, protein binding, disorder, disorder, molecular function activator activity, protein binding, disorder, disorder, disorder, protein binding, protein binding, protein binding, self-inhibition, self-inhibition, disorder, disorder, ubiquitin protein ligase binding, disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: 2.60.40.720, p53-like tetramerisation domain, P53 DNA-binding domain, P53 tetramerisation motif, P53 transactivation motif, Transactivation domain 2
Cross-references: BMRB:18709, ELM:deg_mdm2_1, PDB:1DT7, PDB:1H26, PDB:1JSP, PDB:1UOL, PDB:1XQH, PDB:1YCR, PDB:2B3G, PDB:2FOJ, PDB:2FOO, PDB:2GS0, PDB:2H2D, PDB:2H4J, PDB:2K8F, PDB:2LY4, PDB:2MWO, PDB:2MWP, PDB:2RUK, PDB:3DAB, PDB:3DAC, PDB:3LW1, PDB:3TG5, PDB:4ZZJ
Sequence:
MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
Protein: Cytochrome bo(3) ubiquinol oxidase subunit 2
UniProt accession: P0ABJ1
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW0422, b0432, cyoA
Length: 315 residues
Disorder content (fraction disordered): 0.18412698412698417
Curated region start positions: 284, 1, 284
Curated region end positions: 315, 26, 315
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Cupredoxins -  blue copper proteins, 1.10.287.90, Cytochrome C oxidase subunit II, periplasmic domain, COX Aromatic Rich Motif
Cross-references: PDB:1CYW, PDB:1CYX, PDB:1FFT
Sequence:
MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLILTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIFLAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTPVYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGMKFKAIATPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFADVINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH
Protein: Voltage-gated potassium channel subunit beta-1
UniProt accession: Q14722
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KCNA1B, KCNAB1
Length: 419 residues
Disorder content (fraction disordered): 0.14797136038186157
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 62, 62, 62, 62
Curated region terms: disorder, flexible N-terminal tail, molecular function inhibitor activity, protein binding
Domain/feature annotations: NADP-dependent oxidoreductase domain, Aldo/keto reductase family
Sequence:
MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
Protein: DNA repair protein complementing XP-A cells homolog
UniProt accession: P27088
Organism: Xenopus laevis
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Amphibia, Batrachia, Anura, Pipoidea, Pipidae, Xenopodinae, Xenopus, Xenopus
Gene names: xpa, xpac
Length: 267 residues
Disorder content (fraction disordered): 0.5655430711610487
Curated region start positions: 1, 1, 199, 199
Curated region end positions: 84, 84, 265, 265
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: XPA C-terminal domain, XPA protein N-terminal, XPA protein C-terminus
Sequence:
MEPEPEPEQEANKEEEKILSAAVRAKIERNRQRALMLRQARLACRPYPTGEGISTVKAPPKVIDSGGGFFIEEEEAEEQHVENVVRQPGPVLECDYLICEECGKDFMDSYLSNHFDLAVCDSCRDAEEKHKLITRTEAKQEYLLKDCDIDKREPVLKFILKKNPHNTHWGDMKLYLKAQVIKRSLEVWGSEEALEEAKEVRKDNRDKMKQKKFDKKVKELRRTVRSSLWKKEASGHQHEYGPEEHVEEDSYKKTCITCGYEMNYEKM
Protein: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
UniProt accession: Q08209
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CALNA, CNA, PPP3CA
Length: 521 residues
Disorder content (fraction disordered): 0.2763915547024952
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 374, 487, 373, 373, 373, 373, 373, 1, 487, 373, 388, 388, 389, 389, 393, 393, 393
Curated region end positions: 13, 468, 521, 466, 466, 466, 468, 468, 13, 521, 466, 466, 466, 413, 413, 411, 411, 411
Curated region terms: disorder, disorder, disorder, disorder, disorder to order, calmodulin binding, disorder to order, calmodulin binding, flexible N-terminal tail, flexible C-terminal tail, order, calmodulin binding, disorder to order, calmodulin binding, calmodulin binding, calmodulin binding, order, disorder to order
Domain/feature annotations: 3.60.21.10, Calcineurin-like phosphoesterase
Cross-references: PDB:1AUI, PDB:2R28
Sequence:
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRINERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
Protein: Tyrosine 3-monooxygenase
UniProt accession: P04177
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Th
Length: 498 residues
Disorder content (fraction disordered): 0.1927710843373494
Curated region start positions: 33, 33, 33, 1, 85, 119, 38, 28, 42, 14
Curated region end positions: 50, 50, 50, 72, 96, 130, 42, 71, 71, 34
Curated region terms: disorder, phosphorylation display site, small molecule binding, disorder, disorder, disorder, phosphorylation display site, disorder, small molecule binding, disorder
Domain/feature annotations: Aromatic amino acid hydroxylase, 3.30.70.260, Biopterin-dependent aromatic amino acid hydroxylase, Tyrosine hydroxylase N terminal, Tyrosine hydroxylase N terminal, Tyrosine 3-monooxygenase-like, ACT domain
Cross-references: PDB:2MDA
Sequence:
MPTPSAPSPQPKGFRRAVSEQDAKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAVASSEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRAVKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKHGEPIPHVEYTAEEIATWKEVYVTLKGLYATHACREHLEGFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFNDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIQRSLEGVQDELHTLAHALSAIS
Protein: Lipoate-protein ligase A subunit 1
UniProt accession: Q9HKT1
Organism: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
Taxonomy: Archaea, Candidatus Thermoplasmatota, Thermoplasmata, Thermoplasmatales, Thermoplasmataceae, Thermoplasma
Gene names: Ta0514, lplA
Length: 262 residues
Disorder content (fraction disordered): 0.05725190839694656
Curated region start positions: 179, 179
Curated region end positions: 193, 193
Curated region terms: disorder, disorder
Domain/feature annotations: Bira Bifunctional Protein; Domain 2, Lipoyl protein ligase A/B catalytic domain
Cross-references: PDB:2C8M
Sequence:
MEGRLLLLETPGNTRMSLAYDEAIYRSFQYGDKPILRFYRHDRSVIIGYFQVAEEEVDLDYMKKNGIMLARRYTGGGAVYHDLGDLNFSVVRSSDDMDITSMFRTMNEAVVNSLRILGLDARPGELNDVSIPVNKKTDIMAGEKKIMGAAGAMRKGAKLWHAAMLVHTDLDMLSAVLKVPDEKFRDKIAKSTRERVANVTDFVDVSIDEVRNALIRGFSETLHIDFREDTITEKEESLARELFDKKYSTEEWNMGLLRKEVV
Protein: Collagen adhesin
UniProt accession: Q53654
Organism: Staphylococcus aureus
Taxonomy: Bacteria, Firmicutes, Bacilli, Bacillales, Staphylococcaceae, Staphylococcus
Gene names: cna
Length: 1183 residues
Disorder content (fraction disordered): 0.01944209636517329
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 332, 164, 164
Curated region end positions: 344, 173, 173
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: 2.60.40.1280, Immunoglobulins, Collagen-binding surface protein Cna, B-type domain, Collagen-binding surface protein Cna, B-type domain, Collagen-binding surface protein Cna, B-type domain, 2.60.40.740, Collagen-binding surface protein Cna, B-type domain, Collagen-binding surface protein Cna, B-type domain, Collagen-binding surface protein Cna, B-type domain, Collagen-binding surface protein Cna, B-type domain, Collagen binding domain, Cna protein B-type domain, Cna protein B-type domain, Cna protein B-type domain, Cna protein B-type domain, Cna protein B-type domain, Cna protein B-type domain, Cna protein B-type domain, Prealbumin-like fold domain
Cross-references: PDB:2F68
Sequence:
MNKNVLKFMVFIMLLNIITPLFNKNEAFAARDISSTNVTDLTVSPSKIEDGGKTTVKMTFDDKNGKIQNGDMIKVAWPTSGTVKIEGYSKTVPLTVKGEQVGQAVITPDGATITFNDKVEKLSDVSGFAEFEVQGRNLTQTNTSDDKVATITSGNKSTNVTVHKSEAGTSSVFYYKTGDMLPEDTTHVRWFLNINNEKSYVSKDITIKDQIQGGQQLDLSTLNINVTGTHSNYYSGQSAITDFEKAFPGSKITVDNTKNTIDVTIPQGYGSYNSFSINYKTKITNEQQKEFVNNSQAWYQEHGKEEVNGKSFNHTVHNINANAGIEGTVKGELKVLKQDKDTKAPIANVKFKLSKKDGSVVKDNQKEIEIITDANGIANIKALPSGDYILKEIEAPRPYTFDKDKEYPFTMKDTDNQGYFTTIENAKAIEKTKDVSAQKVWEGTQKVKPTIYFKLYKQDDNQNTTPVDKAEIKKLEDGTTKVTWSNLPENDKNGKAIKYLVKEVNAQGEDTTPEGYTKKENGLVVTNTEKPIETTSISGEKVWDDKDNQDGKRPEKVSVNLLANGEKVKTLDVTSETNWKYEFKDLPKYDEGKKIEYTVTEDHVKDYTTDINGTTITNKYTPGETSATVTKNWDDNNNQDGKRPTEIKVELYQDGKATGKTAILNESNNWTHTWTGLDEKAKGQQVKYTVEELTKVKGYTTHVDNNDMGNLIVTNKYTPETTSISGEKVWDDKDNQDGKRPEKVSVNLLADGEKVKTLDVTSETNWKYEFKDLPKYDEGKKIEYTVTEDHVKDYTTDINGTTITNKYTPGETSATVTKNWDDNNNQDGKRPTEIKVELYQDGKATGKTAILNESNNWTHTWTGLDEKAKGQQVKYTVEELTKVKGYTTHVDNNDMGNLIVTNKYTPETTSISGEKVWDDKDNQDGKRPEKVSVNLLANGEKVKTLDVTSETNWKYEFKDLPKYDEGKKIEYTVTEDHVKDYTTDINGTTITNKYTPGETSATVTKNWDDNNNQDGKRPTEIKVELYQDGKATGKTAILNESNNWTHTWTGLDEKAKGQQVKYTVDELTKVNGYTTHVDNNDMGNLIVTNKYTPKKPNKPIYPEKPKDKTPPTKPDHSNKVKPTPPDKPSKVDKDDQPKDNKTKPENPLKELPKTGMKIITSWITWVFIGILGLYLILRKRFNS
Protein: Glycine amidinotransferase, mitochondrial
UniProt accession: P50440
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AGAT, GATM
Length: 423 residues
Disorder content (fraction disordered): 0.06146572104018912
Dataset labels: NDDs-related proteins
Curated region start positions: 38
Curated region end positions: 63
Curated region terms: disorder
Domain/feature annotations: L-arginine/glycine Amidinotransferase; Chain A
Cross-references: PDB:1JDW, PDB:2JDW, PDB:3JDW, PDB:4JDW
Sequence:
MLRVRCLRGGSRGAEAVHYIGSRLGRTLTGWVQRTFQSTQAATASSRNSCAADDKATEPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD
Protein: ATP-dependent protease ATPase subunit HslU
UniProt accession: P0A6H5
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3902, b3931, hslU, htpI
Length: 443 residues
Disorder content (fraction disordered): 0.07900677200902935
Curated region start positions: 175
Curated region end positions: 209
Curated region terms: disorder
Domain/feature annotations: 1.10.8.60, ATPase family associated with various cellular activities (AAA), AAA domain (Cdc48 subfamily)
Cross-references: PDB:1DO0, PDB:1DO2
Sequence:
MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFRKKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL