LiteFold/DisProt huggingface dataset:
Protein: LANA
UniProt accession: E5LC01
Organism: Human herpesvirus 8
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Peploviricota, Herviviricetes, Herpesvirales, Herpesviridae, Gammaherpesvirinae, Rhadinovirus
Gene names: ORF73
Length: 1117 residues
Disorder content (fraction disordered): 0.387645478961504
Dataset labels: Viral proteins
Curated region start positions: 1065, 1086, 1086, 640, 325, 586, 1086
Curated region end positions: 1117, 1104, 1104, 880, 423, 625, 1104
Curated region terms: disorder, protein binding, disorder to order, disorder, disorder, disorder, viral life cycle
Domain/feature annotations: Epstein Barr virus nuclear antigen-1, DNA-binding domain, Protein LANA1-like, DNA-binding domain
Cross-references: BMRB:26042, DisProt:DP02334r001, DisProt:DP02334r003, DisProt:DP02334r004, DisProt:DP02334r015, PDB:2ND0
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGNDLHLQPRRKHVADSVDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLSPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQQEPQQREPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQQQQDEQQQQDEQQQQDEQQQEEQEQQEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHLGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
Protein: DNA repair protein RAD51 homolog 1
UniProt accession: Q06609
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RAD51, RAD51A, RECA
Length: 339 residues
Disorder content (fraction disordered): 0.14749262536873156
Curated region start positions: 1, 86, 1
Curated region end positions: 15, 114, 21
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: P-loop containing nucleotide triphosphate hydrolases, 5' to 3' exonuclease, C-terminal subdomain, Rad51, Helix-hairpin-helix domain
Cross-references: EMDB:EMD-9566, EMDB:EMD-9567, PDB:1B22, PDB:5H1B, PDB:5H1C
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
Protein: DNA mismatch repair protein MSH6
UniProt accession: Q03834
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: MSH6, PMS3, YD8557.04C, YDR097C
Length: 1242 residues
Disorder content (fraction disordered): 0.24476650563607089
Curated region start positions: 1, 1
Curated region end positions: 304, 304
Curated region terms: disorder, nucleic acid binding
Domain/feature annotations: MutS, connector domain, DNA repair protein MutS, domain I, 1.10.1420.10, P-loop containing nucleotide triphosphate hydrolases, 1.10.1420.10, MutS domain V, MutS domain I, MutS domain II, MutS family domain IV, MutS domain III, MutS domain III
Sequence:
MAPATPKTSKTAHFENGSTSSQKKMKQSSLLSFFSKQVPSGTPSKKVQKPTPATLENTATDKITKNPQGGKTGKLFVDVDEDNDLTIAEETVSTVRSDIMHSQEPQSDTMLNSNTTEPKSTTTDEDLSSSQSRRNHKRRVNYAESDDDDSDTTFTAKRKKGKVVDSESDEDEYLPDKNDGDEDDDIADDKEDIKGELAEDSGDDDDLISLAETTSKKKFSYNTSHSSSPFTRNISRDNSKKKSRPNQAPSRSYNPSHSQPSATSKSSKFNKQNEERYQWLVDERDAQRRPKSDPEYDPRTLYIPSSAWNKFTPFEKQYWEIKSKMWDCIVFFKKGKFFELYEKDALLANALFDLKIAGGGRANMQLAGIPEMSFEYWAAQFIQMGYKVAKVDQRESMLAKEMREGSKGIVKRELQCILTSGTLTDGDMLHSDLATFCLAIREEPGNFYNETQLDSSTIVQKLNTKIFGAAFIDTATGELQMLEFEDDSECTKLDTLMSQVRPMEVVMERNNLSTLANKIVKFNSAPNAIFNEVKAGEEFYDCDKTYAEIISSEYFSTEEDWPEVLKSYYDTGKKVGFSAFGGLLYYLKWLKLDKNLISMKNIKEYDFVKSQHSMVLDGITLQNLEIFSNSFDGSDKGTLFKLFNRAITPMGKRMMKKWLMHPLLRKNDIESRLDSVDSLLQDITLREQLEITFSKLPDLERMLARIHSRTIKVKDFEKVITAFETIIELQDSLKNNDLKGDVSKYISSFPEGLVEAVKSWTNAFERQKAINENIIVPQRGFDIEFDKSMDRIQELEDELMEILMTYRKQFKCSNIQYKDSGKEIYTIEIPISATKNVPSNWVQMAANKTYKRYYSDEVRALARSMAEAKEIHKTLEEDLKNRLCQKFDAHYNTIWMPTIQAISNIDCLLAITRTSEYLGAPSCRPTIVDEVDSKTNTQLNGFLKFKSLRHPCFNLGATTAKDFIPNDIELGKEQPRLGLLTGANAAGKSTILRMACIAVIMAQMGCYVPCESAVLTPIDRIMTRLGANDNIMQGKSTFFVELAETKKILDMATNRSLLVVDELGRGGSSSDGFAIAESVLHHVATHIQSLGFFATHYGTLASSFKHHPQVRPLKMSILVDEATRNVTFLYKMLEGQSEGSFGMHVASMCGISKEIIDNAQIAADNLEHTSRLVKERDLAANNLNGEVVSVPGGLQSDFVRIAYGDGLKNTKLGSGEGVLNYDWNIKRNVLKSLFSIIDDLQS
Protein: Galactose/lactose metabolism regulatory protein GAL80
UniProt accession: Q06433
Organism: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Kluyveromyces
Gene names: GAL80, KLLA0A08162g
Length: 457 residues
Disorder content (fraction disordered): 0.11597374179431072
Curated region start positions: 328, 395
Curated region end positions: 361, 413
Curated region terms: disorder, disorder
Domain/feature annotations: Oxidoreductase family, NAD-binding Rossmann fold, Gal80p, C-terminal domain
Cross-references: PDB:2NVW
Sequence:
MNNNKRSKLSTVPSSRPIRVGFVGLTSGKSWVAKTHFLAIQQLSSQFQIVALYNPTLKSSLQTIEQLQLKHATGFDSLESFAQYKDIDMIVVSVKVPEHYEVVKNILEHSSQNLNLRYLYVEWALAASVQQAEELYSISQQRANLQTIICLQGRKSPYIVRAKELISEGCIGDINSIEISGNGGWYGYERPMRSPEYLYDIESGVNLISNSFGHTIDVLQYITGSYFQKINAMISNNIPTQFLLDENGKRTKETISKTCPDHLLFQGILENGKVPVSCSFKGGTPVKKLTKNLVIDIHGTKGDLKIEGDAGFVEISNLVLYFYGIKNGNGSSNGTDNNGAAAIKDKEKVTKSPSPSTGTSEEEQTMEVFHLRNYNSVVGNILRIYESIADYHFLGKPESKSSRGPDDLFASTKFDKQGFRFEGFPTFKDAIILHRLIDAVFRSDKEEKTLDVSKIMI
Protein: Gag polyprotein
UniProt accession: P07567
Organism: Mason-Pfizer monkey virus
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Betaretrovirus
Gene names: gag
Length: 657 residues
Disorder content (fraction disordered): 0.091324200913242
Dataset labels: Viral proteins
Curated region start positions: 546, 546
Curated region end positions: 605, 605
Curated region terms: disorder, metal ion binding
Domain/feature annotations: Retroviral GAG p10 protein, Human Immunodeficiency Virus Type 1 Capsid Protein, 1.10.1200.30, Zinc finger, CCHC-type, gag protein p24 N-terminal domain, Retroviral GAG p10 protein, GAG-polyprotein viral zinc-finger, Gag protein p24 C-terminal domain
Cross-references: BMRB:4498, BMRB:4600, PDB:1CL4
Sequence:
MGQELSQHERYVEQLKQALKTRGVKVKYADLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKVPVTAFSYWNLIKELIDKKEVNPQVMAAVAQTEEILKSNSQTDLTKTSQNPDLDLISLDSDDEGAKSSSLQDKGLSSTKKPKRFPVLLTAQTSKDPEDPNPSEVDWDGLEDEAAKYHNPDWPPFLTRPPPYNKATPSAPTVMAVVNPKEELKEKIAQLEEQIKLEELHQALISKLQKLKTGNETVTHPDTAGGLSRTPHWPGQHIPKGKCCASREKEEQIPKDIFPVTETVDGQGQAWRHHNGFDFAVIKELKTAASQYGATAPYTLAIVESVADNWLTPTDWNTLVRAVLSGGDHLLWKSEFFENCRDTAKRNQQAGNGWDFDMLTGSGNYSSTDAQMQYDPGLFAQIQAAATKAWRKLPVKGDPGASLTGVKQGPDEPFADFVHRLITTAGRIFGSAEAGVDYVKQLAYENANPACQAAIRPYRKKTDLTGYIRLCSDIGPSYQQGLAMAAAFSGQTVKDFLNNKNKEKGGCCFKCGKKGHFAKNCHEHAHNNAEPKVPGLCPRCKRGKHWANECKSKTDNQGNPIPPHQGNGWRGQPQAPKQAYGAVSFVPANKNNPFQSLPEPPQEVQDWTSVPPPTQY
Protein: DNA repair protein complementing XP-C cells
UniProt accession: Q01831
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: XPC, XPCC
Length: 940 residues
Disorder content (fraction disordered): 0.13404255319148936
Dataset labels: Cancer-related proteins
Curated region start positions: 815, 815, 815, 815, 815, 847, 847, 847
Curated region end positions: 940, 940, 940, 940, 940, 863, 863, 863
Curated region terms: disorder, disorder, disorder, protein binding, disorder, disorder, disorder to order, protein binding
Domain/feature annotations: Rad4, beta-hairpin domain BHD3, Transglutaminase-like, 3.10.620.30, Rad4 transglutaminase-like domain, Rad4 beta-hairpin domain 1, Rad4 beta-hairpin domain 2, Rad4 beta-hairpin domain 3
Sequence:
MARKRAAGGEPRGRELRSQKSKAKSKARREEEEEDAFEDEKPPKKSLLSKVSQGKRKRGCSHPGGSADGPAKKKVAKVTVKSENLKVIKDEALSDGDDLRDFPSDLKKAHHLKRGATMNEDSNEEEEESENDWEEVEELSEPVLGDVRESTAFSRSLLPVKPVEIEIETPEQAKTRERSEKIKLEFETYLRRAMKRFNKGVHEDTHKVHLLCLLANGFYRNNICSQPDLHAIGLSIIPARFTRVLPRDVDTYYLSNLVKWFIGTFTVNAELSASEQDNLQTTLERRFAIYSARDDEELVHIFLLILRALQLLTRLVLSLQPIPLKSATAKGKKPSKERLTADPGGSSETSSQVLENHTKPKTSKGTKQEETFAKGTCRPSAKGKRNKGGRKKRSKPSSSEEDEGPGDKQEKATQRRPHGRERRVASRVSYKEESGSDEAGSGSDFELSSGEASDPSDEDSEPGPPKQRKAPAPQRTKAGSKSASRTHRGSHRKDPSLPAASSSSSSSKRGKKMCSDGEKAEKRSIAGIDQWLEVFCEQEEKWVCVDCVHGVVGQPLTCYKYATKPMTYVVGIDSDGWVRDVTQRYDPVWMTVTRKCRVDAEWWAETLRPYQSPFMDREKKEDLEFQAKHMDQPLPTAIGLYKNHPLYALKRHLLKYEAIYPETAAILGYCRGEAVYSRDCVHTLHSRDTWLKKARVVRLGEVPYKMVKGFSNRARKARLAEPQLREENDLGLFGYWQTEEYQPPVAVDGKVPRNEFGNVYLFLPSMMPIGCVQLNLPNLHRVARKLDIDCVQAITGFDFHGGYSHPVTDGYIVCEEFKDVLLTAWENEQAVIERKEKEKKEKRALGNWKLLAKGLLIRERLKRRYGPKSEAAAPHTDAGGGLSSDEEEGTSSQAEAARILAASWPQNREDEEKQKLKGGPKKTKREKKAAASHLFPFEQL
Protein: Trigger factor
UniProt accession: P47480
Organism: Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Taxonomy: Bacteria, Tenericutes, Mollicutes, Mycoplasmataceae, Mycoplasma
Gene names: MG238, tig
Length: 444 residues
Disorder content (fraction disordered): 0.038288288288288286
Curated region start positions: 150
Curated region end positions: 166
Curated region terms: disorder
Domain/feature annotations: Trigger factor ribosome-binding domain, Trigger factor, C-terminal domain, 3.10.50.40, FKBP-type peptidyl-prolyl cis-trans isomerase, Bacterial trigger factor protein (TF), Bacterial trigger factor protein (TF) C-terminus
Cross-references: PDB:1HXV
Sequence:
MKLYKVLNSKTTDKSLCLEVEIDPNYWQATQKKLVGEMAKSIKIKGFRPGKIPPNLASQSINKAELMQKSAQNVMNSIYESVQQEEIVASNDNVIDDYPTIDFKTITEQNCVLLFYFDLIPNFQLPDYKKIKDLTPLTKLTEAEFNNEIEKLAKTKSTMVDVSDKKLANGDIAIIDFTGIVDNKKLASASAQNYELTIGSNSFIKGFETGLIAMKVNQKKTLALTFPSDYHVKELQSKPVTFEVVLKAIKKLEFTPMDETNFKSFLPEQFQSFTSLKAFKSYFHKLMENKKQETILQENNQKIRQFLLTNTKLPFLPEALIKLEANRLLKLQQSQAEQYKIPFEKLLSASNITLTELQDRNIKEAKENVTFALVMKKIADIEKIKVDNNKIKAEIENVIAVEYPFASDEMKKQLFFNMEQQKEFVESIIINRLTTTKIVSYSTH
Protein: DNA repair protein RAD4
UniProt accession: P14736
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: RAD4, YER162C
Length: 754 residues
Disorder content (fraction disordered): 0.29442970822281167
Curated region start positions: 633, 1
Curated region end positions: 754, 100
Curated region terms: disorder, disorder
Domain/feature annotations: Rad4, beta-hairpin domain BHD3, Transglutaminase-like, Rad4, beta-hairpin domain BHD2, Rad4, beta-hairpin domain BHD1, Rad4 transglutaminase-like domain, Rad4 beta-hairpin domain 1, Rad4 beta-hairpin domain 3
Sequence:
MNEDLPKEYFELIRKALNEKEAEKAPLSRRRRVRRKNQPLPDAKKKFKTGLNELPRESVVTVNLDSSDDGVVTVPTDDSVEEIQSSEEDYDSEEFEDVTDGNEVAGVEDISVEIKPSSKRNSDARRTSRNVCSNEERKRRKYFHMLYLVCLMVHGFIRNEWINSKRLSRKLSNLVPEKVFELLHPQKDEELPLRSTRKLLDGLKKCMELWQKHWKITKKYDNVGLYMRTWKEIEMSANNKRKFKTLKRSDFLRAVSKGHGDPDISVQGFVAMLRACNVNARLIMSCQPPDFTNMKIDTSLNGNNAYKDMVKYPIFWCEVWDKFSKKWITVDPVNLKTIEQVRLHSKLAPKGVACCERNMLRYVIAYDRKYGCRDVTRRYAQWMNSKVRKRRITKDDFGEKWFRKVITALHHRKRTKIDDYEDQYFFQRDESEGIPDSVQDLKNHPYYVLEQDIKQTQIVKPGCKECGYLKVHGKVGKVLKVYAKRDIADLKSARQWYMNGRILKTGSRCKKVIKRTVGRPKGEAEEEDERLYSFEDTELYIPPLASASGEITKNTFGNIEVFAPTMIPGNCCLVENPVAIKAARFLGVEFAPAVTSFKFERGSTVKPVLSGIVVAKWLREAIETAIDGIEFIQEDDNRKEHLLGALESWNTLLLKLRIRSKLNSTYGKIAEEEPNVTKEQNIADNHDNTETFMGGGFLPGIANHEARPYSEPSEPEDSLDYVSVDKAEESATDDDVGEDYSDFMKELEMSEESD
Protein: UV excision repair protein RAD23
UniProt accession: P32628
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: RAD23, SYGP-ORF29, YEL037C
Length: 398 residues
Disorder content (fraction disordered): 0.6055276381909548
Curated region start positions: 77, 77, 185, 185, 230, 311, 311, 310, 310, 347, 347, 310
Curated region end positions: 147, 147, 265, 265, 254, 355, 355, 346, 398, 395, 395, 346
Curated region terms: disorder, flexible linker, disorder, flexible linker, disorder, disorder, flexible linker, disorder, disorder, order to disorder, order, flexible linker
Domain/feature annotations: XPC-binding domain, DNA helicase RuvA subunit, C-terminal domain, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, DNA helicase RuvA subunit, C-terminal domain, Ubiquitin family, UBA/TS-N domain, UBA/TS-N domain, XPC-binding domain
Cross-references: PDB:2QSF, PDB:2QSG, PDB:2QSH
Sequence:
MVSLTFKNFKKEKVPLDLEPSNTILETKTKLAQSISCEESQIKLIYSGKVLQDSKTVSECGLKDGDQVVFMVSQKKSTKTKVTEPPIAPESATTPGRENSTEASPSTDASAAPAATAPEGSQPQEEQTATTERTESASTPGFVVGTERNETIERIMEMGYQREEVERALRAAFNNPDRAVEYLLMGIPENLRQPEPQQQTAAAAEQPSTAATTAEQPAEDDLFAQAAQGGNASSGALGTTGGATDAAQGGPPGSIGLTVEDLLSLRQVVSGNPEALAPLLENISARYPQLREHIMANPEVFVSMLLEAVGDNMQDVMEGADDMVEGEDIEVTGEAAAAGLGQGEGEGSFQVDYTPEDDQAISRLCELGFERDLVIQVYFACDKNEEAAANILFSDHAD
Protein: DNA repair protein RAD2
UniProt accession: P07276
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: RAD2, YGR258C
Length: 1031 residues
Disorder content (fraction disordered): 0.11542192046556742
Curated region start positions: 642, 664, 642, 642, 669, 642
Curated region end positions: 690, 678, 760, 690, 673, 690
Curated region terms: disorder, protein binding, disorder, protein binding, protein binding, protein binding
Domain/feature annotations: 5'-nuclease, 5'-nuclease, XPG N-terminal domain, XPG I-region
Cross-references: PDB:2LOX
Sequence:
MGVHSFWDIAGPTARPVRLESLEDKRMAVDASIWIYQFLKAVRDQEGNAVKNSHITGFFRRICKLLYFGIRPVFVFDGGVPVLKRETIRQRKERRQGKRESAKSTARKLLALQLQNGSNDNVKNSTPSSGSSVQIFKPQDEWDLPDIPGFKYDKEDARVNSNKTFEKLMNSINGDGLEDIDLDTINPASAEFEELPKATQYLILSSLRLKSRLRMGYSKEQLETIFPNSMDFSRFQIDMVKRRNFFTQKLINTTGFQDGGASKLNEEVINRISGQKSKEYKLTKTNNGWILGLGANDGSDAQKAIVIDDKDAGALVKQLDSNAEDGDVLRWDDLEDNSLKIVRHESSNATTAPQKRSNRSEDEGCDSDECEWEEVELKPKNVKFVEDFSLKAARLPYMGQSLNNAGSKSFLDKRHDQASPSKTTPTMRISRISVEDDDEDYLKQIEEIEMMEAVQLSKMEKKPEADDKSKIAKPVTSKGTEARPPIVQYGLLGAQPDSKQPYHVTNLNSKSESVIKRTSKTVLSEFRPPSQQEDKGAILTEGEQNLNFISHKIPQFDFNNENSLLFQKNTESNVSQEATKEKSPIPEMPSWFSSTASQQLYNPYNTTNFVEDKNVRNEQESGAETTNKGSSYELLTGLNATEILERESEKESSNDENKDDDLEVLSEELFEDVPTKSQISKEAEDNDSRKVESINKEHRKPLIFDYDFSEDEEDNIVENMIKEQEEFDTFKNTTLSTSAERNVAENAFVEDELFEQQMKDKRDSDEVTMDMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNMFHEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDYTNGLKGMGPVSSIEVIAEFGNLKNFKDWYNNGQFDKRKQETENKFEKDLRKKLVNNEIILDDDFPSVMVYDAYMRPEVDHDTTPFVWGVPDLDMLRSFMKTQLGWPHEKSDEILIPLIRDVNKRKKKGKQKRINEFFPREYISGDKKLNTSKRISTATGKLKKRKM
Protein: General transcription factor IIE subunit 1
UniProt accession: P29083
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GTF2E1, TF2E1
Length: 439 residues
Disorder content (fraction disordered): 0.03644646924829157
Curated region start positions: 378, 378, 378
Curated region end positions: 393, 393, 393
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: Zinc/RING finger domain, C3HC4 (zinc finger), TFIIE alpha subunit, TFIIB zinc-binding, C-terminal general transcription factor TFIIE alpha
Cross-references: PDB:2RNQ, PDB:2RNR
Sequence:
MADPDVLTEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGIDMDAFQEREEGHAGPDDNEEVMRALLIHEKKTSSAMAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAVAVHKREEDEEEDDEFEEVADDPIVMVAGRPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE
Protein: Pneumococcal histidine triad protein D
UniProt accession: A0A0H2ZP82
Organism: Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Taxonomy: Bacteria, Firmicutes, Bacilli, Lactobacillales, Streptococcaceae, Streptococcus
Gene names: SPD_0889, phtD
Length: 853 residues
Disorder content (fraction disordered): 0.012895662368112544
Curated region start positions: 40
Curated region end positions: 50
Curated region terms: disorder
Domain/feature annotations: 2.30.30.680, 2.30.30.680, 2.30.30.680, 2.30.30.680, Streptococcal histidine triad protein, Streptococcal histidine triad protein, Streptococcal histidine triad protein, Streptococcal histidine triad protein, Streptococcal histidine triad protein
Cross-references: PDB:3ZFJ
Sequence:
MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDGDQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQERSHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKSDLSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGLIFDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHVGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ
Protein: Multiple coagulation factor deficiency protein 2
UniProt accession: Q8NI22
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MCFD2, SDNSF
Length: 146 residues
Disorder content (fraction disordered): 0.821917808219178
Curated region start positions: 27, 27, 27, 27, 53, 53, 66, 113, 113, 66, 102
Curated region end positions: 66, 146, 146, 52, 146, 146, 101, 146, 146, 101, 112
Curated region terms: disorder, disorder, disorder, disorder, order, disorder to order, order, order, disorder to order, disorder to order, disorder
Domain/feature annotations: EF-hand, EF-hand domain pair
Cross-references: BMRB:15789, PDB:2VRG
Sequence:
MTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ
Protein: General transcription and DNA repair factor IIH subunit TFB1
UniProt accession: P32776
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: D9740.3, TFB1, YDR311W
Length: 642 residues
Disorder content (fraction disordered): 0.1853582554517134
Curated region start positions: 64, 65, 66, 64, 64, 65, 64, 67, 122, 394, 447, 518
Curated region end positions: 85, 84, 84, 84, 84, 84, 85, 82, 166, 412, 461, 535
Curated region terms: disorder, disorder, disorder, disorder, flexible linker, flexible linker, flexible linker, disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), BSD domain, BSD domain, TFIIH p62 subunit, N-terminal domain
Cross-references: BMRB:18229, EMDB:12720, PDB:1Y5O, PDB:2GS0, PDB:2L2I, PDB:2LOX, PDB:7O4J
Sequence:
MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMMLRLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEKRRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKLQQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFALSTSQKVGPYNVLSTIKPVASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEKIMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQPGVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDEDNDERNELKIDDLNESYKTNYAIIHLKRNAHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNLINKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKSTLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDVLNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN
Protein: Outer membrane protein YopM
UniProt accession: P17778
Organism: Yersinia pestis
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Yersiniaceae, Yersinia
Gene names: YPCD1.26c, YP_pCD60, y0059, y5054, yop48, yopM
Length: 409 residues
Disorder content (fraction disordered): 0.08068459657701711
Curated region start positions: 1
Curated region end positions: 33
Curated region terms: disorder
Domain/feature annotations: Ribonuclease Inhibitor, Leucine Rich Repeat, Type III secretion system leucine rich repeat protein
Cross-references: PDB:1G9U, PDB:1JL5
Sequence:
MFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERNAPPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLLVDNNNLKALSDLPPLLEYLGVSNNQLEKLPELQNSSFLKIIDVDNNSLKKLPDLPPSLEFIAAGNNQLEELPELQNLPFLTAIYADNNSLKKLPDLPLSLESIVAGNNILEELPELQNLPFLTTIYADNNLLKTLPDLPPSLEALNVRDNYLTDLPELPQSLTFLDVSENIFSGLSELPPNLYYLNASSNEIRSLCDLPPSLEELNVSNNKLIELPALPPRLERLIASFNHLAEVPELPQNLKQLHVEYNPLREFPDIPESVEDLRMNSERVVDPYEFAHETTDKLEDDVFE
Protein: Serine/arginine-rich splicing factor 1
UniProt accession: Q07955
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ASF, OK/SW-cl.3, SF2, SF2P33, SFRS1, SRSF1
Length: 248 residues
Disorder content (fraction disordered): 0.2701612903225806
Dataset labels: Condensates-related proteins, RNA-binding proteins
Curated region start positions: 196, 107, 196, 196, 204, 242
Curated region end positions: 215, 120, 248, 248, 219, 247
Curated region terms: disorder, disorder, disorder, disorder to order, phosphorylation display site, phosphorylation display site
Domain/feature annotations: 3.30.70.330, 3.30.70.330, RNA recognition motif, RNA recognition motif
Cross-references: PDB:2O3D
Sequence:
MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT