LiteFold/DisProt huggingface dataset:
Protein: Flagellin
UniProt accession: P06179
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Salmonella
Gene names: STM1959, flaF, fliC, hag
Length: 495 residues
Disorder content (fraction disordered): 0.21212121212121213
Curated region start positions: 1, 455
Curated region end positions: 65, 494
Curated region terms: disorder, disorder
Domain/feature annotations: f41 fragment of flagellin, C-terminal domain, f41 fragment of flagellin, N-terminal domain, f41 fragment of flagellin, middle domain, Bacterial flagellin N-terminal helical region, Bacterial flagellin C-terminal helical region, Flagellin D3 domain, Flagellin, barrel domain
Sequence:
MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDTLNVQQKYKVSDTAATVTGYADTTIALDNSTFKASATGLGGTDQKIDGDLKFDDTTGKYYAKVTVTGGTGKDGYYEVSVDKTNGEVTLAGGATSPLTGGLPATATEDVKNVQVANADLTEAKAALTAAGVTGTASVVKMSYTDNNGKTIDGGLAVKVGDDYYSATQNKDGSISINTTKYTADDGTSKTALNKLGGADGKTEVVSIGGKTYAASKAEGHNFKAQPDLAEAAATTTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITNLGNTVNNLTSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR
Protein: Negative regulator of flagellin synthesis
UniProt accession: P26477
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Salmonella
Gene names: STM1172, flgM, flgR, mviS
Length: 97 residues
Disorder content (fraction disordered): 1
Curated region start positions: 41, 41, 41, 1
Curated region end positions: 97, 97, 97, 97
Curated region terms: molecular function inhibitor activity, disorder to order, protein binding, disorder
Domain/feature annotations: Anti-sigma-28 factor, FlgM
Sequence:
MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLSDAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTGKIADSLIREAQSYLQSK
Protein: Eukaryotic translation initiation factor 4E-binding protein 1
UniProt accession: Q13541
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: EIF4EBP1
Length: 118 residues
Disorder content (fraction disordered): 1
Dataset labels: Autophagy-related proteins
Curated region start positions: 4, 47, 51, 49, 5, 1, 49, 50, 5, 4, 49, 51, 51, 50, 50, 51, 51, 109, 109, 109, 4, 49, 51, 51, 51, 50
Curated region end positions: 118, 66, 63, 68, 118, 118, 83, 63, 118, 118, 83, 64, 67, 84, 63, 66, 64, 118, 118, 118, 118, 68, 64, 67, 67, 83
Curated region terms: disorder, protein binding, protein binding, translation initiation factor binding, disorder, disorder, protein binding, protein binding, disorder, translation initiation factor binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, disorder, protein binding, disorder to order, negative regulation of translation, negative regulation of translation, disorder to order, translation initiation factor binding, disorder to order, eukaryotic initiation factor 4E binding
Domain/feature annotations: Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)
Cross-references: PDB:1EJ4, PDB:1EJH, PDB:1WKW, PDB:2JGB, PDB:2JGC, PDB:2V8W, PDB:2V8X, PDB:2V8Y, PDB:3HXG, PDB:3HXI, PDB:3M93, PDB:3M94, PDB:3U7X, PDB:4UED, PDB:5BXV, PDB:5EKV, PDB:5NVN, PDB:5WBJ
Sequence:
MSGGSSCSQTPSRAIPATRRVVLGDGVQLPPGDYSTTPGGTLFSTTPGGTRIIYDRKFLMECRNSPVTKTPPRDLPTIPGVTSPSSDEPPMEASQSHLRNSPEDKRAGGEESQFEMDI
Protein: Glial cell line-derived neurotrophic factor
UniProt accession: Q07731
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Gdnf
Length: 211 residues
Disorder content (fraction disordered): 0.17061611374407584
Curated region start positions: 78
Curated region end positions: 113
Curated region terms: disorder
Domain/feature annotations: Cystine-knot cytokines, Transforming growth factor beta like domain
Cross-references: PDB:1AGQ
Sequence:
MKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAEDHSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI
Protein: Glucocorticoid receptor
UniProt accession: P04150
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GRL, NR3C1
Length: 777 residues
Disorder content (fraction disordered): 0.6666666666666666
Dataset labels: Condensates-related proteins
Curated region start positions: 77, 77, 181, 209, 77, 77, 1, 1, 1, 275, 291
Curated region end positions: 262, 262, 244, 213, 262, 262, 518, 500, 500, 279, 295
Curated region terms: disorder, disorder, disorder, phosphorylation display site, protein binding, TBP-class protein binding, disorder, protein binding, TBP-class protein binding, molecular recognition display site, molecular recognition display site
Domain/feature annotations: Erythroid Transcription Factor GATA-1, subunit A, Retinoid X Receptor, Ligand-binding domain of nuclear hormone receptor, Double treble clef zinc finger, C4 type, Glucocorticoid receptor
Cross-references: EMDB:23050, PDB:7KW7
Sequence:
MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK
Protein: Glycine N-methyltransferase
UniProt accession: P13255
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Fbp-cII, Gnmt
Length: 293 residues
Disorder content (fraction disordered): 0.13993174061433447
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 18, 41, 41, 41
Curated region terms: disorder, disorder, self-inhibition, order to disorder
Domain/feature annotations: Glycine N-methyltransferase, chain A, domain 1, Vaccinia Virus protein VP39, Methyltransferase domain
Cross-references: PDB:1D2C, PDB:1D2H, PDB:1NBI
Sequence:
MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG
Protein: Glycine--tRNA ligase
UniProt accession: P56206
Organism: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomy: Bacteria, Deinococcus-Thermus, Deinococci, Thermales, Thermaceae, Thermus
Gene names: TTHA0543, glyQS, glyS
Length: 506 residues
Disorder content (fraction disordered): 0.1699604743083004
Curated region start positions: 85
Curated region end positions: 170
Curated region terms: disorder
Domain/feature annotations: Anticodon-binding domain, tRNA synthetase class II core domain (G, H, P, S and T), Anticodon binding domain
Cross-references: PDB:1ATI
Sequence:
MPASSLDELVALCKRRGFIFQSSEIYGGLQGVYDYGPLGVELKNNLKQAWWRRNVYERDDMEGLDASVLTHRLVLHYSGHEATFADPMVDNRITKKRYRLDHLLKEQPEEVLKRLYRAMEVEEENLHALVQAMMQAPERAGGAMTAAGVLDPASGEPGDWTPPRYFNMMFKTYVGPVEDEASLAYLRPETAQGIFVNFKNVLDATSRKLPFGIAQIGKAFRNEITPRNFIFRVREFEQMEIEYFVRPGEDEYWHRYWVEERLKWWQEMGLSRENLVPYQQPPEELAHYAKATVDILYRFPHGLEELEGIANRTDFDLGSHTKDQEALGITARVLRNEHSTQRLAYRDPETGKWFVPYVIEPSAGVDRGVLALLAEAFTREELPNGEERIVLKLKPQLAPIKVAVIPLVKNRPEITEYAKRLKARLLALGLGRVLYEDTGNIGKAYRRHDEVGTPFAVTVDYDTIGQSKDGTTRLKDTVTVRDRDTMEQIRLHVDELEGFLRERLRW
Protein: Growth hormone receptor
UniProt accession: P10912
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GHR
Length: 638 residues
Disorder content (fraction disordered): 0.5501567398119123
Curated region start positions: 270, 270, 361, 361, 270
Curated region end positions: 370, 370, 620, 620, 357
Curated region terms: disorder, disorder, disorder, disorder, lipid binding
Domain/feature annotations: Immunoglobulins, Immunoglobulins, Fibronectin type III domain, Erythropoietin receptor, ligand binding, Growth hormone receptor binding
Sequence:
MDLWQLLLTLALAGSSDAFSGSEATAAILSRAPWSLQSVNPGLKTNSSKEPKFTKCRSPERETFSCHWTDEVHHGTKNLGPIQLFYTRRNTQEWTQEWKECPDYVSAGENSCYFNSSFTSIWIPYCIKLTSNGGTVDEKCFSVDEIVQPDPPIALNWTLLNVSLTGIHADIQVRWEAPRNADIQKGWMVLEYELQYKEVNETKWKMMDPILTTSVPVYSLKVDKEYEVRVRSKQRNSGNYGEFSEVLYVTLPQMSQFTCEEDFYFPWLLIIIFGIFGLTVMLFVFLFSKQQRIKMLILPPVPVPKIKGIDPDLLKEGKLEEVNTILAIHDSYKPEFHSDDSWVEFIELDIDEPDEKTEESDTDRLLSSDHEKSHSNLGVKDGDSGRTSCCEPDILETDFNANDIHEGTSEVAQPQRLKGEADLLCLDQKNQNNSPYHDACPATQQPSVIQAEKNKPQPLPTEGAESTHQAAHIQLSNPSSLSNIDFYAQVSDITPAGSVVLSPGQKNKAGMSQCDMHPEMVSLCQENFLMDNAYFCEADAKKCIPVAPHIKVESHIQPSLNQEDIYITTESLTTAAGRPGTGEHVPGSEMPVPDYTSIHIVQSPQGLILNATALPLPDKEFLSSCGYVSTDQLNKIMP
Protein: Attachment protein G3P
UniProt accession: P03661
Organism: Enterobacteria phage fd
Taxonomy: Viruses, Monodnaviria, Loebvirae, Hofneiviricota, Faserviricetes, Tubulavirales, Inoviridae, Inovirus, unclassified Inovirus
Gene names: III
Length: 424 residues
Disorder content (fraction disordered): 0.05188679245283019
Dataset labels: Viral proteins
Curated region start positions: 86, 86
Curated region end positions: 107, 107
Curated region terms: disorder, flexible linker
Domain/feature annotations: Minor Coat Protein; Domain 2, Phage FD Coat Protein,Membrane penetration domain, Phage Coat Protein A, Phage Coat Protein A
Cross-references: PDB:2G3P
Sequence:
MKKLLFAIPLVVPFYSHSAETVESCLAKPHTENSFTNVWKDDKTLDRYANYEGCLWNATGVVVCTGDETQCYGTWVPIGLAIPENEGGGSEGGGSEGGGSEGGGTKPPEYGDTPIPGYTYINPLDGTYPPGTEQNPANPNPSLEESQPLNTFMFQNNRFRNRQGALTVYTGTVTQGTDPVKTYYQYTPVSSKAMYDAYWNGKFRDCAFHSGFNEDPFVCEYQGQSSDLPQPPVNAGGGSGGGSGGGSEGGGSEGGGSEGGGSEGGGSGGGSGSGDFDYEKMANANKGAMTENADENALQSDAKGKLDSVATDYGAAIDGFIGDVSGLANGNGATGDFAGSNSQMAQVGDGDNSPLMNNFRQYLPSLPQSVECRPYVFGAGKPYEFSIDCDKINLFRGVFAFLLYVATFMYVFSTFANILRNKES
Protein: Heat shock factor protein
UniProt accession: P22121
Organism: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Kluyveromyces
Gene names: HSF, KLLA0D03322g
Length: 677 residues
Disorder content (fraction disordered): 0.3087149187592319
Curated region start positions: 260, 1, 1, 1
Curated region end positions: 273, 195, 195, 195
Curated region terms: disorder, disorder, disorder, molecular function activator activity
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, HSF-type DNA-binding
Sequence:
MGHNDSVETMDEISNPNNILLPHDGTGLDATGISGSQEPYGMVDVLNPDSLKDDSNVDEPLIEDIVNPSLDPEGVVSAEPSNEVGTPLLQQPISLDHVITRPASAGGVYSIGNSSTSSAAKLSDGDLTNATDPLLNNAHGHGQPSSESQSHSNGYHKQGQSQQPLLSLNKRKLLAKAHVDKHHSKKKLSTTRARPAFVNKLWSMVNDKSNEKFIHWSTSGESIVVPNRERFVQEVLPKYFKHSNFASFVRQLNMYGWHKVQDVKSGSMLSNNDSRWEFENENFKRGKEYLLENIVRQKSNTNILGGTTNAEVDIHILLNELETVKYNQLAIAEDLKRITKDNEMLWKENMMARERHQSQQQVLEKLLRFLSSVFGPNSAKTIGNGFQPDLIHELSDMQVNHMSNNNHNNTGNINPNAYHNETDDPMANVFGPLTPTDQGKVPLQDYKLRPRLLLKNRSMSSSSSSNLNQRQSPQNRIVGQSPPPQQQQQQQQQQGQPQGQQFSYPIQGGNQMMNQLGSPIGTQVGSPVGSQYGNQYGNQYSNQFGNQLQQQTSRPALHHGSNGEIRELTPSIVSSDSPDPAFFQDLQNNIDKQEESIQEIQDWITKLNPGPGEDGNTPIFPELNMPSYFANTGGSGQSEQPSDYGDSQIEELRNSRLHEPDRSFEEKNNGQKRRRAA
Protein: High mobility group protein HMG-I/HMG-Y
UniProt accession: P17096
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HMGA1, HMGIY
Length: 107 residues
Disorder content (fraction disordered): 1
Dataset labels: Cancer-related proteins, RNA-binding proteins
Curated region start positions: 1, 51, 51, 80, 80, 80, 1, 51, 76, 100, 6, 1, 9, 50, 1, 1, 70, 1, 1, 1, 1, 1, 69, 63, 81, 50, 1, 1, 1
Curated region end positions: 107, 75, 75, 89, 89, 89, 107, 55, 80, 105, 11, 107, 75, 91, 107, 107, 80, 107, 107, 107, 107, 107, 73, 67, 89, 91, 107, 107, 107
Curated region terms: disorder, DNA binding, disorder to order, disorder to order, DNA binding, DNA binding, bending, disorder, phosphorylation display site, phosphorylation display site, phosphorylation display site, ADP-ribosylation display site, molecular adaptor activity, DNA binding, DNA binding, molecular adaptor activity, protein binding, flexible linker, DNA binding, RNA binding, RNA binding, molecular function activator activity, protein binding, acetylation display site, acetylation display site, DNA binding, transcription coactivator activity, transcription coactivator activity, protein binding, protein binding
Cross-references: PDB:2EZD, PDB:2EZE, PDB:2EZF, PDB:2EZG, PDB:3uxw
Sequence:
MSESSSKSSQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGSKNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEEGISQESSEEEQ
Protein: Non-histone chromosomal protein H6
UniProt accession: P02315
Organism: Oncorhynchus mykiss
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Actinopterygii, Neopterygii, Teleostei, Protacanthopterygii, Salmoniformes, Salmonidae, Salmoninae, Oncorhynchus
Length: 70 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 10, 1
Curated region end positions: 70, 35, 70
Curated region terms: disorder, nucleic acid binding, disorder
Domain/feature annotations: HMG14 and HMG17
Sequence:
MPKRKSATKGDEPARRSARLSARPVPKPAAKPKKAAAPKKAVKGKKAAENGDAKAEAKVQAAGDGAGNAK
Protein: Protein TonB
UniProt accession: P02929
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW5195, b1252, exbA, tonB
Length: 239 residues
Disorder content (fraction disordered): 0.20502092050209209
Curated region start positions: 103
Curated region end positions: 151
Curated region terms: disorder
Domain/feature annotations: TonB, Gram-negative bacterial TonB protein C-terminal, TonB polyproline region
Cross-references: PDB:1XX3
Sequence:
MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ
Protein: Histone H5
UniProt accession: P02259
Organism: Gallus gallus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Archelosauria, Archosauria, Dinosauria, Saurischia, Theropoda, Coelurosauria, Aves, Neognathae, Galloanserae, Galliformes, Phasianidae, Phasianinae, Gallus
Length: 190 residues
Disorder content (fraction disordered): 0.5947368421052631
Curated region start positions: 1, 99, 102, 101
Curated region end positions: 21, 109, 190, 190
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, linker histone H1 and H5 family
Cross-references: PDB:1HST
Sequence:
MTESLVLSPAPAKPKRVKASRRSASHPTYSEMIAAAIRAEKSRGGSSRQSIQKYIKSHYKVGHNADLQIKLSIRRLLAAGVLKQTKGVGASGSFRLAKSDKAKRSPGKKKKAVRRSTSPKKAARPRKARSPAKKPKATARKARKKSRASPKKAKKPKTVKAKSRKASKAKKVKRSKPRAKSGARKSPKKK
Protein: Myelin basic protein
UniProt accession: P02687
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: MBP
Length: 169 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 169, 169, 169, 169, 169, 109
Curated region terms: disorder, disorder to order, lipid binding, disorder, lipid binding, lipid binding
Domain/feature annotations: Myelin basic protein
Sequence:
AAQKRPSQRSKYLASASTMDHARHGFLPRHRDTGILDSLGRFFGSDRGAPKRGSGKDGHHAARTTHYGSLPQKAQGHRPQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRASDYKSAHKGLKGHDAQGTLSKIFKLGGRDSRSGSPMARR
Protein: Protein Nef
UniProt accession: P03406
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 206 residues
Disorder content (fraction disordered): 0.2621359223300971
Dataset labels: Viral proteins
Curated region start positions: 58, 149, 149, 54, 149, 71, 71, 71, 71
Curated region end positions: 77, 178, 178, 70, 177, 77, 77, 77, 77
Curated region terms: disorder, disorder, flexible linker, disorder, disorder, protein binding, SH3 domain binding, viral life cycle, protein binding
Domain/feature annotations: Nef Regulatory Factor, HIV 1 nef anchor domain, Negative factor, (F-Protein) or Nef
Cross-references: PDB:1AVV, PDB:1AVZ, PDB:1EFN
Sequence:
MGGKWSKSSVVGWPTVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAATNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: Myelin transcription factor 1-like protein
UniProt accession: P70475
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Myt1l, Nzf1
Length: 1187 residues
Disorder content (fraction disordered): 0.17101937657961247
Curated region start positions: 487, 487, 487, 487, 487, 487, 487, 487, 487, 487, 487, 90
Curated region end positions: 606, 606, 606, 606, 606, 606, 606, 606, 606, 606, 606, 172
Curated region terms: disorder, disorder to order, disorder to order, DNA binding, DNA binding, zinc ion binding, zinc ion binding, zinc ion binding, metal ion sequestering activity, metal ion sequestering activity, metal ion sequestering activity, disorder
Domain/feature annotations: Zinc finger, C2HC type, Zinc finger, C2HC type, Zinc finger, C2HC type, Zinc finger, C2HC type, Zinc finger, C2HC type, Zinc finger, C2HC type, Myelin transcription factor 1
Sequence:
MDVDAEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECYESDGTEDMDDKEEDDDEEFSEDNDEQGDDDDEDEVDREDEEEIEEEDDEDDEDDDDGDDVEEEEDDDDEEEEEEEEEEENEDHQMSCTRIMQDPEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENISDRSYAEGMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQDRSQPPNMSVRQHVRQEDDFPGRTPDRSYSDMMNLMRLEEQLSPRSRTFSSCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMDAGRRDNLRSYEDQSPRQLAGEDRKSKSSDSHVKKPYYDPSRTEKRESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHENVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSNQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKNASPSSSTTSSYAPSSSSNLSCGGGSSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCTARNPDMEVDENGTLDLSMNKQRPRDSCCPVLTPLEPMSPQQQAVMSSRCFQLSEGDCWDLPVDYTKMKPRRVDEEDPKEITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQELKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQVTITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV
Protein: Ornithine decarboxylase
UniProt accession: P07805
Organism: Trypanosoma brucei brucei
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Trypanosoma
Length: 423 residues
Disorder content (fraction disordered): 0.13947990543735225
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1, 296, 410, 410, 1
Curated region end positions: 32, 308, 423, 423, 32
Curated region terms: disorder, disorder, disorder, flexible C-terminal tail, flexible N-terminal tail
Domain/feature annotations: Lyase, Ornithine Decarboxylase; Chain A, domain 1, Alanine racemase, Pyridoxal-dependent decarboxylase, pyridoxal binding domain
Cross-references: PDB:1QU4, PDB:2TOD
Sequence:
MDIVVNDDLSCRFLEGFNTRDALCKKISMNTCDEGDPFFVADLGDIVRKHETWKKCLPRVTPFYAVKCNDDWRVLGTLAALGTGFDCASNTEIQRVRGIGVPPEKIIYANPCKQISHIRYARDSGVDVMTFDCVDELEKVAKTHPKAKMVLRISTDDSLARCRLSVKFGAKVEDCRFILEQAKKLNIDVTGVSFHVGSGSTDASTFAQAISDSRFVFDMGTELGFNMHILDIGGGFPGTRDAPLKFEEIAGVINNALEKHFPPDLKLTIVAEPGRYYVASAFTLAVNVIAKKVTPGVQTDVGAHAESNAQSFMYYVNDGVYGSFNCILYDHAVVRPLPQREPIPNEKLYPSSVWGPTCDGLDQIVERYYLPEMQVGEWLLFEDMGAYTVVGTSSFNGFQSPTIYYVVSGLPDHVVRELKSQKS
Protein: Phenylalanine--tRNA ligase alpha subunit
UniProt accession: P27001
Organism: Thermus thermophilus
Taxonomy: Bacteria, Deinococcus-Thermus, Deinococci, Thermales, Thermaceae, Thermus
Gene names: pheS
Length: 350 residues
Disorder content (fraction disordered): 0.2885714285714286
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 101, 101, 84, 84, 101
Curated region terms: disorder, disorder to order, disorder, flexible N-terminal tail, tRNA binding
Domain/feature annotations: Bira Bifunctional Protein; Domain 2, tRNA synthetases class II core domain (F), Aminoacyl tRNA synthetase class II, N-terminal domain
Cross-references: PDB:1EIY, PDB:1PYS
Sequence:
MLEEALAAIQNARDLEELKALKARYLGKKGLLTQEMKGLSALPLEERRKRGQELNAIKAALEAALEAREKALEEAALKEALERERVDVSLPGASLFSGGLHPITLMERELVEIFRALGYQAVEGPEVESEFFNFDALNIPEHHPARDMWDTFWLTGEGFRLEGPLGEEVEGRLLLRTHTSPMQVRYMVAHTPPFRIVVPGRVFRFEQTDATHEAVFHQLEGLVVGEGIAMAHLKGAIYELAQALFGPDSKVRFQPVYFPFVEPGAQFAVWWPEGGKWLELGGAGMVHPKVFQAVDAYRERLGLPPAYRGVTGFAFGLGVERLAMLRYGIPDIRYFFGGRLKFLEQFKGVL
Protein: Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
UniProt accession: P78356
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PIP4K2B, PIP5K2B
Length: 416 residues
Disorder content (fraction disordered): 0.21634615384615383
Curated region start positions: 1, 304, 373
Curated region end positions: 33, 342, 390
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: 2-Layer Sandwich, Phosphatidylinositol Phosphate Kinase II Beta, 2-Layer Sandwich, Phosphatidylinositol-4-phosphate 5-Kinase
Cross-references: PDB:1BO1
Sequence:
MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT