LiteFold/DisProt huggingface dataset:
Protein: Myb family transcription factor PHL4
UniProt accession: Q8GXC2
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At2g20400, F11A3.5, PHL4
Length: 397 residues
Disorder content (fraction disordered): 0.6448362720403022
Curated region start positions: 1, 1, 1, 1, 369
Curated region end positions: 227, 227, 227, 227, 397
Curated region terms: disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Myb-like DNA-binding domain, MYB-CC type transfactor, LHEQLE motif
Cross-references: BMRB:52524, BMRB:52525
Sequence:
MIPNDDDDANSMKNYPLNDDDANSMKNYPLNDDDANSMENYPLRSIPTELSHTCSLIPPSLPNPSEAAADMSFNSELNQIMARPCDMLPANGGAVGHNPFLEPGFNCPETTDWIPSPLPHIYFPSGSPNLIMEDGVIDEIHKQSDLPLWYDDLITTDEDPLMSSILGDLLLDTNFNSASKVQQPSMQSQIQQPQAVLQQPSSCVELRPLDRTVSSNSNNNSNSNNAAAAAKGRMRWTPELHEVFVDAVNQLGGSNEATPKGVLKHMKVEGLTIFHVKSHLQKYRTAKYIPVPSEGSPEARLTPLEQITSDDTKRGIDITETLRIQMEHQKKLHEQLESLRTMQLRIEEQGKALLMMIEKQNMGFGGPEQGEKTSAKTPENGSEESESPRPKRPRNEE
Protein: Isoform 3 of Microtubule-associated protein 2
UniProt accession: P15146-3
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Map2, Mtap2
Length: 467 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 80, 80, 65, 288, 185, 60, 60, 60
Curated region end positions: 467, 159, 118, 118, 69, 294, 198, 70, 70, 70
Curated region terms: disorder, protein kinase binding, protein kinase binding, disorder to order, phosphorylation display site, protein binding, protein binding, protein binding, SH2 domain binding, disorder to order
Sequence:
MADERKDEGKAPHWTSASLTEAAAHPHSPEMKDQGGSGEGLSRSANGFPYREEEEGAFGEHGSQGTYSDTKENGINGELTSADRETAEEVSARIVQVVTAEAVAVLKGEQEKEAQHKDQPAALPLAAEETVNLPPSPPPSPASEQTAALEEATSGESAQAPSAFKQAKDKVTDGITKSPEKRSSLPRPSSILPPRRGVSGDREENSFSLNSSISSARRTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTPSYPRTPGTPKSGILVPSEKKVAIIRTPPKSPATPKQLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPSRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL
Protein: Chromobox protein homolog 5
UniProt accession: P45973
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CBX5, HP1A
Length: 191 residues
Disorder content (fraction disordered): 0.418848167539267
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 79, 178, 178, 79, 1
Curated region end positions: 21, 123, 191, 191, 123, 21
Curated region terms: disorder, disorder, disorder, flexible C-terminal tail, flexible linker, flexible N-terminal tail
Domain/feature annotations: Chromo (CHRromatin Organisation MOdifier) domain, Chromo shadow domain
Sequence:
MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKETAKS
Protein: Paratox
UniProt accession: A0A0H2UWN8
Organism: Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
Taxonomy: Bacteria, Bacillota, Bacilli, Lactobacillales, Streptococcaceae, Streptococcus
Gene names: SpyM3_1300
Length: 60 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 5, 32, 30, 5, 1, 1
Curated region end positions: 60, 60, 60, 60, 60, 10, 44, 35, 10, 60, 60
Curated region terms: disorder, disorder, order, disorder to order, protein binding, protein binding, protein binding, protein binding, protein binding, negative regulation of DNA binding, negative regulation of establishment of competence for transformation
Domain/feature annotations: Paratox
Cross-references: PDB:7N10, PDB:7N1N
Sequence:
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDK
Protein: RNA and export factor binding protein 2
UniProt accession: Q4KL64
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Alyref2, Refbp2
Length: 218 residues
Disorder content (fraction disordered): 0.3348623853211009
Dataset labels: RNA-binding proteins
Curated region start positions: 1
Curated region end positions: 73
Curated region terms: disorder
Domain/feature annotations: RNA recognition motif, C-terminal duplication domain of Friend of PRMT1
Cross-references: EMDB:40739, PDB:8SRR
Sequence:
MADKMDMSLDDIIKLNRNQRRVNRGGGPRRNRPAIARGGRNRPAPYSRPKPLPDKWQHDLFDSGCGGGEGVETGAKLLVSNLDFGVSDADIQELFAEFGTLKKAAVDYDRSGRSLGTADVHFERRADALKAMKQYKGVPLDGRPMDIQLVTSQIDPQRRPAQSGNRGGMTRNRGSGGFGGRGSQGRGRGTGRNSKQQQLSAEELDAQLDAYNARRDTS
Protein: Uncharacterized protein 56B
UniProt accession: Q8QL46
Organism: Sulfolobus islandicus rod-shaped virus 1
Taxonomy: Viruses, Adnaviria, Zilligvirae, Taleaviricota, Tokiviricetes, Ligamenvirales, Rudiviridae, Icerudivirus, Icerudivirus SIRV1
Gene names: 56B
Length: 56 residues
Disorder content (fraction disordered): 0.21428571428571427
Dataset labels: Viral proteins
Curated region start positions: 1, 1
Curated region end positions: 12, 12
Curated region terms: disorder, flexible N-terminal tail
Domain/feature annotations: 56B-like, Ribbon-helix-helix
Cross-references: PDB:2KEL
Sequence:
MQTQEQSQKKKQKAVFGIYMDKDLKTRLKVYCAKNNLQLTQAIEEAIKEYLQKRNG
Protein: Uncharacterized protein
UniProt accession: C8ZKB3
Organism: Pseudomonas phage LUZ7
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Uroviricota, Caudoviricetes, Schitoviridae, Migulavirinae, Luzseptimavirus, Luzseptimavirus LUZ7
Length: 99 residues
Disorder content (fraction disordered): 0.1717171717171717
Dataset labels: Viral proteins
Curated region start positions: 1, 1
Curated region end positions: 17, 17
Curated region terms: disorder, flexible N-terminal tail
Cross-references: PDB:6QLC
Sequence:
MALVKKNQARNTQATDNKGASAYLNFHFPTRDGKDVRLVSLGLRADDALHMQLQEFLTVDDKGKPLSETAYAERCKKLVSRLIIKLGVTRSEEERALDL
Protein: ParBC domain-containing protein
UniProt accession: Q1D3H3
Organism: Myxococcus xanthus (strain DK1622)
Taxonomy: Bacteria, Myxococcota, Myxococcia, Myxococcales, Cystobacterineae, Myxococcaceae, Myxococcus
Gene names: MXAN_4634, padC
Length: 489 residues
Disorder content (fraction disordered): 0.1390593047034765
Curated region start positions: 422, 422
Curated region end positions: 489, 489
Curated region terms: disorder, flexible C-terminal tail
Domain/feature annotations: ParB N-terminal domain
Cross-references: PDB:6RYK
Sequence:
MRARGLFRGATMDAEHRVDGQDGTAGAGPEGGSQAPSGQDGGQGGAVSAELHASGGPSGPQGEHRREDASPESGGEHRAEGTPPAEGSEQRAEGTPAAEGSEQRAEGKPSEQGVAQRAEDTPSEQGEPQNAGSAQGQGGEPPVASGDTQGEGERPHNAGGEAPGSADASGSEGSKDQAGSQEGGLQAEGTTSQGQAEPPAKDASHAQGEHQAVSDSHGQDGSESGGRSVANEEARAEQSPSDGEARVTPGLDERPQGAFWTGEADGDKSGDSDEASREDVLPEPEQRLSGRVTTVLLPLEKLQDESAFKLRPEGDVSGLATDIARLGQLFPVDVRPAGEDRYQLVCGFRRVAALRFLKRDAVQARIHLRLSDEDALVMSLAEAIHATPVGPEVLEAKRDELEAQGRLSAAVRDMLEKALATEDTLAPEGVEEEIDADELAQEVAQRLGAINQDLSLLADVFAALDESRKAELLMQLRYSSELVTYLEGL
Protein: Diphtheria toxin repressor
UniProt accession: P0DJL7
Organism: Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Taxonomy: Bacteria, Actinomycetota, Actinomycetes, Mycobacteriales, Corynebacteriaceae, Corynebacterium
Gene names: DIP1414, dtxR
Length: 226 residues
Disorder content (fraction disordered): 0.0752212389380531
Curated region start positions: 130, 130
Curated region end positions: 146, 144
Curated region terms: disorder, protein binding
Domain/feature annotations: Iron dependent repressor, N-terminal DNA binding domain, Iron dependent repressor, metal binding and dimerisation domain, Diphteria toxin repressor SH3 domain
Cross-references: PDB:1BYM
Sequence:
MKDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERDGLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEACRWEHVMSDEVERRLVKVLKDVSRSPFGNPIPGLDELGVGNSDAAVPGTRVIDAATSMPRKVRIVQINEIFQVETDQFTQLLDADIRVGSEVEIVDRDGHITLSHNGKDVELIDDLAHTIRIEEL
Protein: H/ACA ribonucleoprotein complex subunit DKC1
UniProt accession: O60832
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DKC1, NOLA4
Length: 514 residues
Disorder content (fraction disordered): 0.2237354085603113
Dataset labels: NDDs-related proteins, RNA-binding proteins
Curated region start positions: 1, 1, 422, 422
Curated region end positions: 22, 22, 514, 514
Curated region terms: disorder, flexible N-terminal tail, disorder, flexible C-terminal tail
Domain/feature annotations: PUA domain, TruB family pseudouridylate synthase (N terminal domain), DKCLD (NUC011) domain, tRNA pseudouridylate synthase B C-terminal domain
Cross-references: EMDB:17190, EMDB:17191, PDB:8OUE, PDB:8OUF
Sequence:
MADAEVIILPKKHKKKKERKSLPEEDVAEIQHAEEFLIKPESKVAKLDTSQWPLLLKNFDKLNVRTTHYTPLACGSNPLKREIGDYIRTGFINLDKPSNPSSHEVVAWIRRILRVEKTGHSGTLDPKVTGCLIVCIERATRLVKSQQSAGKEYVGIVRLHNAIEGGTQLSRALETLTGALFQRPPLIAAVKRQLRVRTIYESKMIEYDPERRLGIFWVSCEAGTYIRTLCVHLGLLLGVGGQMQELRRVRSGVMSEKDHMVTMHDVLDAQWLYDNHKDESYLRRVVYPLEKLLTSHKRLVMKDSAVNAICYGAKIMLPGVLRYEDGIEVNQEIVVITTKGEAICMAIALMTTAVISTCDHGIVAKIKRVIMERDTYPRKWGLGPKASQKKLMIKQGLLDKHGKPTDSTPATWKQEYVDYSESAKKEVVAEVVKAPQVVAEAAKTAKRKRESESESDETPPAAPQLIKKEKKKSKKDKKAKAGLESGAEPGDGDSDTTKKKKKKKKAKEVELVSE
Protein: H/ACA ribonucleoprotein complex subunit 2
UniProt accession: Q9NX24
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSPC286, NHP2, NOLA2
Length: 153 residues
Disorder content (fraction disordered): 0.1437908496732026
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 1
Curated region end positions: 22, 22
Curated region terms: disorder, flexible N-terminal tail
Domain/feature annotations: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Cross-references: EMDB:17190, EMDB:17191, PDB:8OUE, PDB:8OUF
Sequence:
MTKIKADPDGPEAQAEACSGERTYQELLVNQNPIAQPLASRRLTRKLYKCIKKAVKQKQIRRGVKEVQKFVNKGEKGIMVLAGDTLPIEVYCHLPVMCEDRNLPYVYIPSKTDLGAAAGSKRPTCVIMVKPHEEYQEAYDECLEEVQSLPLPL
Protein: H/ACA ribonucleoprotein complex subunit 1
UniProt accession: Q9NY12
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GAR1, NOLA1
Length: 217 residues
Disorder content (fraction disordered): 0.5529953917050692
Curated region start positions: 162, 162, 1, 1
Curated region end positions: 217, 217, 64, 64
Curated region terms: disorder, flexible C-terminal tail, flexible N-terminal tail, disorder
Domain/feature annotations: Gar1/Naf1 RNA binding region
Cross-references: EMDB:17190, EMDB:17191, PDB:8OUE, PDB:8OUF
Sequence:
MSFRGGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQGPPERVVLLGEFLHPCEDDIVCKCTTDENKVPYFNAPVYLENKEQIGKVDEIFGQLRDFYFSVKLSENMKASSFKKLQKFYIDPYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGGFRGRGH
Protein: Histone-lysine N-methyltransferase, H3 lysine-9 specific
UniProt accession: O60016
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Taphrinomycotina, Schizosaccharomycetes, Schizosaccharomycetales, Schizosaccharomycetaceae, Schizosaccharomyces
Gene names: SPBC428.08c, clr4, kmt1
Length: 490 residues
Disorder content (fraction disordered): 0.2510204081632653
Curated region start positions: 69, 69, 69, 113, 164, 164, 147
Curated region end positions: 191, 191, 191, 170, 174, 170, 151
Curated region terms: disorder, flexible linker, nucleosome binding, nucleosome binding, disorder to order, histone methyltransferase activity (H3-K9 specific), histone methyltransferase activity (H3-K9 specific)
Domain/feature annotations: Chromo (CHRromatin Organisation MOdifier) domain, SET domain, Pre-SET motif
Cross-references: BMRB:27903, BMRB:27905
Sequence:
MSPKQEEYEVERIVDEKLDRNGAVKLYRIRWLNYSSRSDTWEPPENLSGCSAVLAEWKRRKRRLKGSNSDSDSPHHASNPHPNSRQKHQHQTSKSVPRSQRFSRELNVKKENKKVFSSQTTKRQSRKQSTALTTNDTSIILDDSLHTNSKKLGKTRNEVKEESQKRELVSNSIKEATSPKTSSILTKPRNPSKLDSYTHLSFYEKRELFRKKLREIEGPEVTLVNEVDDEPCPSLDFQFISQYRLTQGVIPPDPNFQSGCNCSSLGGCDLNNPSRCECLDDLDEPTHFAYDAQGRVRADTGAVIYECNSFCSCSMECPNRVVQRGRTLPLEIFKTKEKGWGVRSLRFAPAGTFITCYLGEVITSAEAAKRDKNYDDDGITYLFDLDMFDDASEYTVDAQNYGDVSRFFNHSCSPNIAIYSAVRNHGFRTIYDLAFFAIKDIQPLEELTFDYAGAKDFSPVQSQKSQQNRISKLRRQCKCGSANCRGWLFG
Protein: Cytochrome c-552
UniProt accession: P54820
Organism: Paracoccus denitrificans
Taxonomy: Bacteria, Pseudomonadota, Alphaproteobacteria, Rhodobacterales, Paracoccaceae, Paracoccus
Gene names: cycM
Length: 176 residues
Disorder content (fraction disordered): 0.18181818181818185
Curated region start positions: 48, 38, 38
Curated region end positions: 69, 47, 69
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: Cytochrome c
Cross-references: PDB:3M97
Sequence:
MFDTMTVTKAAGALIGSLLFLLLMSWAASGIFHVGTSGHGAEGEEHAQAYTYPVESAGGAEGEAVDEGPDFATVLASADPAAGEKVFGKCKACHKLDGNDGVGPHLNGVVGRTVAGVDGFNYSDPMKAHGGDWTPEALQEFLTNPKAVVKGTKMAFAGLPKIEDRANLIAYLEGQQ
Protein: Insulin-like growth factor 2 mRNA-binding protein 1
UniProt accession: Q9NZI8
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CRDBP, IGF2BP1, VICKZ1, ZBP1
Length: 577 residues
Disorder content (fraction disordered): 0.17157712305025996
Dataset labels: RNA-binding proteins, Condensates-related proteins
Curated region start positions: 157, 344, 179, 394, 170, 179, 388, 179, 394, 157, 344
Curated region end positions: 194, 404, 183, 398, 175, 183, 395, 183, 398, 194, 404
Curated region terms: disorder, disorder, regulation of stress granule assembly, regulation of stress granule assembly, RNA binding, negative regulation of RNA binding, self-assembly, phosphorylation display site, phosphorylation display site, flexible linker, flexible linker
Domain/feature annotations: KH domain, KH domain, KH domain, KH domain, RNA recognition motif, RNA recognition motif
Cross-references: BMRB:52567, BMRB:52568
Sequence:
MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK
Protein: Polycomb protein SUZ12
UniProt accession: Q15022
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CHET9, JJAZ1, KIAA0160, SUZ12
Length: 739 residues
Disorder content (fraction disordered): 0.36535859269282817
Dataset labels: Cancer-related proteins, NDDs-related proteins, RNA-binding proteins
Curated region start positions: 168, 256, 323, 364, 497, 150, 201, 251, 380, 497, 201, 201
Curated region end positions: 181, 293, 350, 422, 513, 188, 241, 367, 423, 510, 241, 241
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, order, disorder to order
Domain/feature annotations: VEFS-Box of polycomb protein, Polycomb protein SUZ12-like, Zn domain
Cross-references: PDB:5WAI, PDB:5WAK
Sequence:
MAPQKHGGGGGGGSGPSAGSGGGGFGGSAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGAAVLPVKKPKMEHVQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIKRKTFKVDDMLSKVEKMKGEQESHSLSAHLQLTFTGFFHKNDKPSPNSENEQNSVTLEVLLVKVCHKKRKDVSCPIRQVPTGKKQVPLNPDLNQTKPGNFPSLAVSSNEFEPSNSHMVKSYSLLFRVTRPGRREFNGMINGETNENIDVNEELPARRKRNREDGEKTFVAQMTVFDKNRRLQLLDGEYEVAMQEMEECPISKKRATWETILDGKRLPPFETFSQGPTLQFTLRWTGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQTRKEKDTPNENRQKLRIFYQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYVYHPKGARIDVSINECYDGSYAGNPQDIHRQPGFAFSRNGPVKRTPITHILVCRPKRTKASMSEFLESEDGEVEQQRTYSSGHNRLYFHSDTCLPLRPQEMEVDSEDEKDPEWLREKTITQIEEFSDVNEGEKEVMKLWNLHVMKHGFIADNQMNHACMLFVENYGQKIIKKNLCRNFMLHLVSMHDFNLISIMSIDKAVTKLREMQQKLEKGESASPANEEITEEQNGTANGFSEINSKEKALETDSVSGVSKQSKKQKL
Protein: Non-homologous end-joining factor 1
UniProt accession: Q9H9Q4
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NHEJ1, XLF
Length: 299 residues
Disorder content (fraction disordered): 0.23745819397993312
Curated region start positions: 229, 295, 282
Curated region end positions: 299, 299, 294
Curated region terms: disorder, protein binding, DNA binding
Domain/feature annotations: XLF N-terminal domain, XLF protein coiled-coil region
Cross-references: BMRB:52387
Sequence:
MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKELNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWNFHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
Protein: Neurofilament light polypeptide
UniProt accession: P07196
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NEFL, NF68, NFL
Length: 543 residues
Disorder content (fraction disordered): 0.04419889502762431
Dataset labels: Age-related disorders proteins
Curated region start positions: 40, 40, 40
Curated region end positions: 63, 63, 63
Curated region terms: disorder, tubulin binding, disorder
Domain/feature annotations: Intermediate filament protein, Intermediate filament head (DNA binding) region
Sequence:
MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD
Protein: Alpha-crystallin A chain
UniProt accession: P02489
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CRYA1, CRYAA, HSPB4
Length: 173 residues
Disorder content (fraction disordered): 0.4913294797687861
Curated region start positions: 149, 1
Curated region end positions: 173, 60
Curated region terms: disorder, disorder
Domain/feature annotations: Hsp20/alpha crystallin family, Alpha crystallin A chain, N terminal
Cross-references: BMRB:27109
Sequence:
MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVSREEKPTSAPSS
Protein: Heat shock protein beta-1
UniProt accession: P04792
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSP27, HSP28, HSPB1
Length: 205 residues
Disorder content (fraction disordered): 0.13658536585365855
Dataset labels: Condensates-related proteins
Curated region start positions: 178
Curated region end positions: 205
Curated region terms: disorder
Domain/feature annotations: Hsp20/alpha crystallin family
Cross-references: BMRB:26994
Sequence:
MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
Protein: Cyclic AMP-dependent transcription factor ATF-4
UniProt accession: P18848
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ATF4, CREB2, TXREB
Length: 351 residues
Disorder content (fraction disordered): 0.7834757834757835
Dataset labels: Autophagy-related proteins
Curated region start positions: 1
Curated region end positions: 275
Curated region terms: disorder
Domain/feature annotations: bZIP transcription factor
Cross-references: BMRB:51062
Sequence:
MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP
Protein: Protein phosphatase 1 regulatory subunit 15B
UniProt accession: Q5SWA1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PPP1R15B
Length: 713 residues
Disorder content (fraction disordered): 1
Dataset labels: NDDs-related proteins
Curated region start positions: 414, 556, 414, 557, 425, 420, 420, 1, 414, 639, 1, 1, 340, 639, 639, 426, 471, 421, 474
Curated region end positions: 613, 571, 613, 561, 430, 425, 425, 713, 639, 713, 713, 713, 639, 713, 713, 439, 495, 431, 480
Curated region terms: disorder, eukaryotic initiation factor eIF2 binding, disorder, eukaryotic initiation factor eIF2 binding, eukaryotic initiation factor eIF2 binding, eukaryotic initiation factor eIF2 binding, protein phosphatase regulator activity, disorder, eukaryotic initiation factor eIF2 binding, protein phosphatase 1 binding, protein phosphatase type 1 complex, protein phosphatase type 1 complex, eukaryotic initiation factor eIF2 binding, protein phosphatase 1 binding, protein phosphatase regulator activity, eukaryotic initiation factor eIF2 binding, eukaryotic initiation factor eIF2 binding, eukaryotic initiation factor eIF2 binding, eukaryotic initiation factor eIF2 binding
Domain/feature annotations: eIF2-alpha phosphatase phosphorylation constitutive repressor, Phosphatase-1 catalytic subunit binding region
Cross-references: BMRB:52233
Sequence:
MEPGTGGSRKRLGPRAGFRFWPPFFPRRSQAGSSKFPTPLGPENSGNPTLLSSAQPETRVSYWTKLLSQLLAPLPGLLQKVLIWSQLFGGMFPTRWLDFAGVYSALRALKGREKPAAPTAQKSLSSLQLDSSDPSVTSPLDWLEEGIHWQYSPPDLKLELKAKGSALDPAAQAFLLEQQLWGVELLPSSLQSRLYSNRELGSSPSGPLNIQRIDNFSVVSYLLNPSYLDCFPRLEVSYQNSDGNSEVVGFQTLTPESSCLREDHCHPQPLSAELIPASWQGCPPLSTEGLPEIHHLRMKRLEFLQQASKGQDLPTPDQDNGYHSLEEEHSLLRMDPKHCRDNPTQFVPAAGDIPGNTQESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEKEPGEGRISVVDYSYLEGDLPISARPACSNKLIDYILGGASSDLETSSDPEGEDWDEEAEDDGFDSDSSLSDSDLEQDPEGLHLWNSFCSVDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPETPEHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGENEKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQESECPDSVQRDVLSGGRHTHVKRKKVTFLEEVTEYYISGDEDRKGPWEEFARDGCRFQKRIQETEDAIGYCLTFEHRERMFNRLQGTCFKGLNVLKQC