LiteFold/DisProt huggingface dataset:
Protein: Nucleoporin NUP145
UniProt accession: P49687
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: NUP145, RAT10, YGL092W
Length: 1317 residues
Disorder content (fraction disordered): 0.0979498861047836
Dataset labels: Condensates-related proteins, RNA-binding proteins
Curated region start positions: 606
Curated region end positions: 734
Curated region terms: disorder
Domain/feature annotations: Peptidase S59, nucleoporin, 2.20.25.480, 1.25.40.690, Nup98-96 autopeptidase S59, Nuclear protein 96, Nucleoporin FG repeat region
Cross-references: PDB:7N9F
Sequence:
MFNKSVNSGFTFGNQNTSTPTSTPAQPSSSLQFPQKSTGLFGNVNVNANTSTPSPSGGLFNANSNANSISQQPANNSLFGNKPAQPSGGLFGATNNTTSKSAGSLFGNNNATANSTGSTGLFSGSNNIASSTQNGGLFGNSNNNNITSTTQNGGLFGKPTTTPAGAGGLFGNSSSTNSTTGLFGSNNTQSSTGIFGQKPGASTTGGLFGNNGASFPRSGETTGTMSTNPYGINISNVPMAVADMPRSITSSLSDVNGKSDAEPKPIENRRTYSFSSSVSGNAPLPLASQSSLVSRLSTRLKATQKSTSPNEIFSPSYSKPWLNGAGSAPLVDDFFSSKMTSLAPNENSIFPQNGFNFLSSQRADLTELRKLKIDSNRSAAKKLKLLSGTPAITKKHMQDEQDSSENEPIANADSVTNIDRKENRDNNLDNTYLNGKEQSNNLNKQDGENTLQHEKSSSFGYWCSPSPEQLERLSLKQLAAVSNFVIGRRGYGCITFQHDVDLTAFTKSFREELFGKIVIFRSSKTVEVYPDEATKPMIGHGLNVPAIITLENVYPVDKKTKKPMKDTTKFAEFQVFDRKLRSMREMNYISYNPFGGTWTFKVNHFSIWGLVNEEDAEIDEDDLSKQEDGGEQPLRKVRTLAQSKPSDKEVILKTDGTFGTLSGKDDSIVEEKAYEPDLSDADFEGIEASPKLDVSKDWVEQLILAGSSLRSVFATSKEFDGPCQNEIDLLFSECNDEIDNAKLIMKERRFTASYTFAKFSTGSMLLTKDIVGKSGVSIKRLPTELQRKFLFDDVYLDKEIEKVTIEARKSNPYPQISESSLLFKDALDYMEKTSSDYNLWKLSSILFDPVSYPYKTDNDQVKMALLKKERHCRLTSWIVSQIGPEIEEKIRNSSNEIEQIFLYLLLNDVVRASKLAIESKNGHLSVLISYLGSNDPRIRDLAELQLQKWSTGGCSIDKNISKIYKLLSGSPFEGLFSLKELESEFSWLCLLNLTLCYGQIDEYSLESLVQSHLDKFSLPYDDPIGVIFQLYAANENTEKLYKEVRQRTNALDVQFCWYLIQTLRFNGTRVFSKETSDEATFAFAAQLEFAQLHGHSLFVSCFLNDDKAAEDTIKRLVMREITLLRASTNDHILNRLKIPSQLIFNAQALKDRYEGNYLSEVQNLLLGSSYDLAEMAIVTSLGPRLLLSNNPVQNNELKTLREILNEFPDSERDKWSVSINVFEVYLKLVLDNVETQETIDSLISGMKIFYDQYKHCREVAACCNVMSQEIVSKILEKNNPSIGDSKAKLLELPLGQPEKAYLRGEFAQDLMKCTYKI
Protein: Nucleoporin NUP85
UniProt accession: P46673
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: J1624, NUP85, RAT9, YJR042W
Length: 744 residues
Disorder content (fraction disordered): 0.08736559139784947
Curated region start positions: 1, 432
Curated region end positions: 46, 450
Curated region terms: disorder, disorder
Domain/feature annotations: 2.20.25.500, Nup85 Nucleoporin
Cross-references: PDB:6X08
Sequence:
MTIDDSNRLLMDVDQFDFLDDGTAQLSNNKTDEEEQLYKRDPVSGAILVPMTVNDQPIEKNGDKMPLKFKLGPLSYQNMAFITAKDKYKLYPVRIPRLDTSKEFSAYVSGLFEIYRDLGDDRVFNVPTIGVVNSNFAKEHNATVNLAMEAILNELEVFIGRVKDQDGRVNRFYELEESLTVLNCLRTMYFILDGQDVEENRSEFIESLLNWINRSDGEPDEEYIEQVFSVKDSTAGKKVFETQYFWKLLNQLVLRGLLSQAIGCIERSDLLPYLSDTCAVSFDAVSDSIELLKQYPKDSSSTFREWKNLVLKLSQAFGSSATDISGELRDYIEDFLLVIGGNQRKILQYSRTWYESFCGFLLYYIPSLELSAEYLQMSLEANVVDITNDWEQPCVDIISGKIHSILPVMESLDSCTAAFTAMICEAKGLIENIFEGEKNSDDYSNEDNEMLEDLFSYRNGMASYMLNSFAFELCSLGDKELWPVAIGLIALSATGTRSAKKMVIAELLPHYPFVTNDDIEWMLSICVEWRLPEIAKEIYTTLGNQMLSAHNIIESIANFSRAGKYELVKSYSWLLFEASCMEGQKLDDPVLNAIVSKNSPAEDDVIIPQDILDCVVTNSMRQTLAPYAVLSQFYELRDREDWGQALRLLLLLIEFPYLPKHYLVLLVAKFLYPIFLLDDKKLMDEDSVATVIEVIETKWDDADEKSSNLYETIIEADKSLPSSMATLLKNLRKKLNFKLCQAFM
Protein: Nucleoporin NUP120
UniProt accession: P35729
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: NUP120, RAT2, YKL057C, YKL313, YKL314
Length: 1037 residues
Disorder content (fraction disordered): 0.022179363548698167
Curated region start positions: 30
Curated region end positions: 52
Curated region terms: disorder
Domain/feature annotations: Nucleoporin Nup120/160, beta-propeller domain, Nucleoporin NUP120, helical domain, Nucleoporin Nup120, HEAT repeats
Cross-references: PDB:3h7n
Sequence:
MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLTFYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTVRVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYDSVISCKLFHERYLIVLTQNCHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIPTNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSEHDLDIVTKTGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYNHSLYKLNTTVENWFYNMHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLENQFEITNLKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLSIHYRITLQVLLTFVLFDLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFFMTFFRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLKSENYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFRMFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWECFKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDLRDELRGL
Protein: Nucleoporin NUP133
UniProt accession: P36161
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: NUP133, RAT3, YKR082W, YKR402
Length: 1157 residues
Disorder content (fraction disordered): 0.04753673292999136
Curated region start positions: 1, 1
Curated region end positions: 55, 55
Curated region terms: disorder, protein binding
Domain/feature annotations: 1.25.40.700, Nup133 N terminal like
Cross-references: PMID:19706512
Sequence:
MSEKKVHLRLRKELSVPIAVVENESLAQLSYEEESQASLMDISMEQQQLRLHSHFDNSKVFTENNRYIVKTLQTDYSSGFSNDDELNGYIDMQIGYGLVNDHKKVYIWNIHSTQKDTPYITVPFRSDDNDEIAVAPRCILTFPATMDESPLALNPNDQDETGGLIIIKGSKAIYYEDINSINNLNFKLSEKFSHELELPINSSGGEKCDLMLNCEPAGIVLSTNMGRIFFITIRNSMGKPQLKLGKLLNKPFKLGIWSKIFNTNSSVVSLRNGPILGKGTRLVYITTNKGIFQTWQLSATNSHPTKLIDVNIYEAILESLQDLYPFAHGTLKIWDSHPLQDESSQLFLSSIYDSSCNETYYILSTIIFDSSSNSFTIFSTYRLNTFMESITDTKFKPKIFIPQMENANDTNEVTSILVMFPNAVVITQVNSKLDSSYSMRRKWEDIVSLRNDIDIIGSGYDSKSLYVLTKQMGVLQFFVKENEETNSKPEVGFVKSHVDQAVYFSKINANPIDFNLPPEISLDQESIEHDLKLTSEEIFHSNGKYIPPMLNTLGQHLSVRKEFFQNFLTFVAKNFNYKISPELKLDLIEKFEILNCCIKFNSIIRQSDVLNDIWEKTLSNYNLTQNEHLTTKTVVINSPDVFPVIFKQFLNHVVFVLFPSQNQNFKLNVTNLINLCFYDGILEEGEKTIRYELLELDPMEVDTSKLPWFINFDYLNCINQCFFDFTFACEEEGSLDSYKEGLLKIVKILYYQFNQFKIWINTQPVKSVNANDNFININNLYDDNHLDWNHVLCKVNLKEQCIQIAEFYKDLSGLVQTLQTLDQNDSTTVSLYETFFNEFPKEFSFTLFEYLIKHKKLNDLIFRFPQQHDVLIQFFQESAPKYGHVAWIQQILDGSYADAMNTLKNITVDDSKKGESLSECELHLNVAKLSSLLVEKDNLDINTLRKIQYNLDTIDAEKNISNKLKKGEVQICKRFKNGSIREVFNILVEELKSTTVVNLSDLVELYSMLDDEESLFIPLRLLSVDGNLLNFEVKKFLNALVWRRIVLLNASNEGDKLLQHIVKRVFDEELPKNNDFPLPSVDLLCDKSLLTPEYISETYGRFPIDQNAIREEIYEEISQVETLNSDNSLEIKLHSTIGSVAKEKNYTINYETNTVEY
Protein: Cell wall assembly regulator SMI1
UniProt accession: P32566
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: G8553, KNR4, KTR4, SMI1, YGR229C
Length: 505 residues
Disorder content (fraction disordered): 0.3287128712871287
Curated region start positions: 340
Curated region end positions: 505
Curated region terms: disorder
Domain/feature annotations: SMI1 / KNR4 family (SUKH-1)
Sequence:
MDLFKRKVKEWVYSLSTDDHYAEYNPDETPTFNMGKRLNSNNGQVNPSQMHLNSVDEEMSMGFQNGVPSNEDINIDEFTSTESNDGVSETLLAWRHIDFWTSEHNPDLNATLSDPCTQNDITHAEEDLEVSFPNPVKASFKIHDGQEDLESMTGTSGLFYGFQLMTLDQVVAMTQAWRNVAKNLNKRSQQGLSHVTSTGSSSSMERLNGNKFKLPNIPDQKSIPPNAVQPVYAHPAWIPLITDNAGNHIGVDLAPGPNGKYAQIITFGRDFDTKFVIAENWGEFLLSFANDLEAGNWYLVDDNDDYFSGDGELVFRDKKSNGPIQDYFEVLKRRTWIKYQENLRSQQQKSQPDTSLQEQKYVPASQKKVAAEQPSTLNAESIKGEDSGSADVQSVQDHESVKIVKTEPSEAETTTVNTESLGQAEHEIKADNVDIKQESERKEDEKQPKVEEKEHVENEHVTESAKKDDDVNKQTEEMNKKEENEIRSDDAKVEEAREEFENIAL
Protein: Isoform 2 of Fibroblast growth factor 12
UniProt accession: P61328-2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FGF12, FGF12B, FHF1
Length: 181 residues
Disorder content (fraction disordered): 0.1878453038674033
Curated region start positions: 148
Curated region end positions: 181
Curated region terms: disorder
Cross-references: PDB:4JQ0
Sequence:
MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST
Protein: Arachidonate 15-lipoxygenase
UniProt accession: P16050
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ALOX15, LOG15
Length: 662 residues
Disorder content (fraction disordered): 0.21299093655589124
Curated region start positions: 22
Curated region end positions: 162
Curated region terms: disorder
Domain/feature annotations: PLAT/LH2 domain, Lipoxygenase-1; Domain 5, Lipoxygenase-1; Domain 5, Lipoxygenase, PLAT/LH2 domain
Sequence:
MGLYRIRVSTGASLYAGSNNQVQLWLVGQHGEAALGKRLWPARGKETELKVEVPEYLGPLLFVKLRKRHLLKDDAWFCNWISVQGPGAGDEVRFPCYRWVEGNGVLSLPEGTGRTVGEDPQGLFQKHREEELEERRKLYRWGNWKDGLILNMAGAKLYDLPVDERFLEDKRVDFEVSLAKGLADLAIKDSLNVLTCWKDLDDFNRIFWCGQSKLAERVRDSWKEDALFGYQFLNGANPVVLRRSAHLPARLVFPPGMEELQAQLEKELEGGTLFEADFSLLDGIKANVILCSQQHLAAPLVMLKLQPDGKLLPMVIQLQLPRTGSPPPPLFLPTDPPMAWLLAKCWVRSSDFQLHELQSHLLRGHLMAEVIVVATMRCLPSIHPIFKLIIPHLRYTLEINVRARTGLVSDMGIFDQIMSTGGGGHVQLLKQAGAFLTYSSFCPPDDLADRGLLGVKSSFYAQDALRLWEIIYRYVEGIVSLHYKTDVAVKDDPELQTWCREITEIGLQGAQDRGFPVSLQARDQVCHFVTMCIFTCTGQHASVHLGQLDWYSWVPNAPCTMRLPPPTTKDATLETVMATLPNFHQASLQMSITWQLGRRQPVMVAVGQHEEEYFSGPEPKAVLKKFREELAALDKEIEIRNAKLDMPYEYLRPSVVENSVAI
Protein: Ncstrn_small domain-containing protein
UniProt accession: F0ZBA6
Organism: Dictyostelium purpureum
Taxonomy: Eukaryota, Amoebozoa, Evosea, Eumycetozoa, Dictyostelia, Dictyosteliales, Dictyosteliaceae, Dictyostelium
Gene names: DICPUDRAFT_96800, ncstn
Length: 643 residues
Disorder content (fraction disordered): 0.02177293934681182
Curated region start positions: 19
Curated region end positions: 32
Curated region terms: disorder
Domain/feature annotations: Zn peptidases, Nicastrin large lobe, Nicastrin small lobe
Cross-references: PDB:4R12
Sequence:
MRFKNVLVLLLLLVFSVINSEPSAPATISDNIYTTLYSSYPCTKIMTSDGQFGCSSKHGGNSGILYLIDDDESYNNYFSYSQQKDIIVVLDTNYFNSTSVLNLHNKSKIEGIIVLTDTKKTYPYSPDSRYPNKIYGLYPNSNLEWNPNADGFTYFSFPFPIFAIDNQTSVAIRNVSKHNRDGQYPAWGAELDSFMQGAINSETCLRRGFCEPVGGQSIWSSFSSKIDKEKEIILVMLPFDTTAFFRDLSIGADQSSFATVTLLSVIKSLAAVDRSSWNKEVVFAFWNAERWGYVGSEYFINDLLNFQCKTYNSDKSKCIDPPRADLAFQTQINFTKISTIIELNQIGRAQLDKNLGKYSLYLHTAGTKTSSVTDILDQVASSYENSTITFKPTTQTELPPSSSMSFLKKTNKIPVVVITDHDYKYSNPYYGYEQDDNENVLGSTLNDIVYILSTFIDRIAGGNNNITIDKNFINILYPCFTSSITCFNILMKTYPLNEVPNFYSSVFGTSLTTTLSPYETKLIHRLLYSITQYNSTLTNCTSDNDCPSSLCYSGQCVSSNTHLHNALSLGFDFDTSKNVWKIVNSSYPIFTESNWDYTALKVFKIGNSTTEIWFLVSGLIELLVSIGLILYVKKFLSNRYKLL
Protein: Isoform tumor suppressor ARF of Tumor suppressor ARF
UniProt accession: Q8N726-1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CDKN2, CDKN2A, MLM
Length: 132 residues
Disorder content (fraction disordered): 1
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 57, 1, 1, 1, 1, 1, 84, 84, 1, 1, 1, 85, 1, 1
Curated region end positions: 132, 132, 14, 14, 14, 14, 14, 103, 103, 22, 22, 34, 101, 132, 132
Curated region terms: disorder, disorder, disorder, protein binding, disorder to order, protein binding, amyloid fibril formation, protein binding, protein binding, MDM2/MDM4 family protein binding, protein localization to nucleolus, regulation of ubiquitin protein ligase activity, protein localization to nucleus, regulation of protein stability, nuclear body organization
Sequence:
MVRRFLVTLRIRRACGPPRVRVFVVHIPRLTGEWAAPGAPAAVALVLMLLRSQRLGQQPLPRRPGHDDGQRPSGGAAAAPRRGAQLRRPRHSHPTRARRCPGGLPGHAGGAAPGRGAAGRARCLGPSARGPG
Protein: Multidrug resistance ABC transporter ATP-binding and permease protein
UniProt accession: Q72J05
Organism: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Taxonomy: Bacteria, Deinococcus-Thermus, Deinococci, Thermales, Thermaceae, Thermus
Gene names: TT_C0976
Length: 600 residues
Disorder content (fraction disordered): 0.02666666666666667
Curated region start positions: 304
Curated region end positions: 319
Curated region terms: disorder
Domain/feature annotations: ABC transporter type 1, transmembrane domain, P-loop containing nucleotide triphosphate hydrolases, ABC transporter, ABC transporter transmembrane region
Cross-references: PDB:5MKK
Sequence:
MTEDTYSKAFDRALFARILRYVWPYRLQVVLALLFLLVVTLAAAATPLFFKWAIDLALVPTEPRPLAERFHLLLWISLGFLAVRAVHFAATYGETYLIQWVGQRVLFDLRSDLFAKLMRLHPGFYDRNPVGRLMTRVTSDVDAINQFITGGLVGVIADLFTLVGLLGFMLFLSPKLTLVVLLVAPVLLAVTTWVRLGMRSAYREMRLRLARVNAALQENLSGVETIQLFVKEREREEKFDRLNRDLFRAWVEIIRWFALFFPVVGFLGDFAVASLVYYGGGEVVRGAVSLGLLVAFVDYTRQLFQPLQDLSDKFNLFQGAMASAERIFGVLDTEEELKDPEDPTPIRGFRGEVEFRDVWLAYTPKGVEPTEKDWVLKGVSFRVRPGEKVALVGATGAGKTSVVSLIARFYDPQRGCVFLDGVDVRRYRQEELRRHVGIVLQEPFLFSGTVLDNLRLFDPSVPPERVEEVARFLGAHEFILRLPKGYQTVLGERGAGLSTGEKQLLALVRALLASPDILLILDEATASVDSETEKRLQEALYKAMEGRTSLIIAHRLSTIRHVDRILVFRKGRLVEEGSHEELLAKGGYYAALYRLQFQEA
Protein: Vitamin B12-binding protein
UniProt accession: P37028
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW0154, b0158, btuF, yadT
Length: 266 residues
Disorder content (fraction disordered): 0.06015037593984962
Curated region start positions: 217
Curated region end positions: 232
Curated region terms: disorder
Domain/feature annotations: Nitrogenase molybdenum iron protein domain, Nitrogenase molybdenum iron protein domain, Periplasmic binding protein
Cross-references: PDB:5m29
Sequence:
MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITPVGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGIKVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFLQFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGPDQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD
Protein: Protein CASC3
UniProt accession: O15234
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CASC3, MLN51
Length: 703 residues
Disorder content (fraction disordered): 1
Curated region start positions: 195, 198, 137, 249, 195, 1, 195, 216, 216, 216, 170, 216, 1, 137, 137, 137, 137
Curated region end positions: 215, 213, 168, 286, 215, 169, 703, 246, 246, 246, 194, 246, 703, 283, 283, 283, 283
Curated region terms: disorder, disorder, disorder, disorder, flexible linker, disorder, disorder, DEAD/H-box RNA helicase binding, disorder to pre-molten globule, flexible linker, pre-molten globule, pre-molten globule, exon-exon junction complex, protein binding, single-stranded RNA binding, regulation of RNA helicase activity, nucleoplasm
Domain/feature annotations: CASC3/Barentsz eIF4AIII binding
Cross-references: PDB:2HYI, PDB:2J0Q, PDB:2J0S, PDB:2XB2, PDB:5XJC
Sequence:
MADRRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRAGFRPVEAGGQHGGRSGETVKHEISYRSRRLEQTSVRDPSPEADAPVLGSPEKEEAASEPPAAAPDAAPPPPDRPIEKKSYSRARRTRTKVGDAVKLAEEVPPPPEGLIPAPPVPETTPTPPTKTGTWEAPVDSSTSGLEQDVAQLNIAEQNWSPGQPSFLQPRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMLVQPGMNLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS
Protein: U1 small nuclear ribonucleoprotein 70 kDa
UniProt accession: P08621
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RNPU1Z, RPU1, SNRNP70, SNRP70, U1AP1
Length: 437 residues
Disorder content (fraction disordered): 0.6567505720823799
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 1, 184, 184, 184, 277, 265, 255, 243, 291, 230, 230, 230
Curated region end positions: 33, 33, 437, 437, 437, 281, 269, 259, 247, 295, 306, 306, 306
Curated region terms: disorder, disorder, disorder, disorder, protein binding, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, protein binding, protein binding, disorder
Domain/feature annotations: 3.30.70.330, RNA recognition motif, U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
Cross-references: PDB:3PGW
Sequence:
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGYLAPENGYLMEAAPE
Protein: Endoplasmic reticulum resident protein 44
UniProt accession: Q9BS26
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ERP44, KIAA0573, TXNDC4, UNQ532/PRO1075
Length: 406 residues
Disorder content (fraction disordered): 0.11330049261083744
Curated region start positions: 361, 361, 380, 380
Curated region end positions: 379, 406, 401, 401
Curated region terms: disorder, disorder, order to disorder, self-regulatory activity
Domain/feature annotations: Glutaredoxin, Glutaredoxin, Glutaredoxin, Thioredoxin, Thioredoxin-like domain
Cross-references: PDB:2R2J, PDB:5HQP
Sequence:
MHPAVFLSLPDLRCSLLLLVTWVFTPVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL
Protein: Transcriptional activator HlyU
UniProt accession: P52695
Organism: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Vibrionales, Vibrionaceae, Vibrio
Gene names: VC_0678, hlyU
Length: 108 residues
Disorder content (fraction disordered): 0.0925925925925926
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 1, 1
Curated region end positions: 10, 10
Curated region terms: disorder, flexible N-terminal tail
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Bacterial regulatory protein, arsR family
Cross-references: PDB:4OOI
Sequence:
MPYLKGAPMNLQEMEKNSAKAVVLLKAMANERRLQILCMLLDNELSVGELSSRLELSQSALSQHLAWLRRDGLVNTRKEAQTVFYTLSSTEVKAMIELLHRLYCQANQ
Protein: Ubiquitin-conjugating enzyme E2 E1
UniProt accession: P51965
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: UBCH6, UBE2E1
Length: 193 residues
Disorder content (fraction disordered): 0.20725388601036268
Curated region start positions: 1, 1, 1
Curated region end positions: 40, 40, 40
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Ubiquitin Conjugating Enzyme, Ubiquitin-conjugating enzyme
Sequence:
MSDDDSRASTSSSSSSSSNQQTEKETNTPKKKESKVSMSKNSKLLSTSAKRIQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT
Protein: ATP-dependent RNA helicase DDX3X
UniProt accession: O00571
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DBX, DDX3, DDX3X
Length: 662 residues
Disorder content (fraction disordered): 0.25226586102719034
Dataset labels: Cancer-related proteins, NDDs-related proteins, Condensates-related proteins
Curated region start positions: 1
Curated region end positions: 167
Curated region terms: disorder
Domain/feature annotations: P-loop containing nucleotide triphosphate hydrolases, P-loop containing nucleotide triphosphate hydrolases, DEAD/DEAH box helicase, Helicase conserved C-terminal domain
Sequence:
MSHVAVENALGLDQQFAGLDLNSSDNQSGGSTASKGRYIPPHLRNREATKGFYDKDSSGWSSSKDKDAYSSFGSRSDSRGKSSFFSDRGSGSRGRFDDRGRSDYDGIGSRGDRSGFGKFERGGNSRWCDKSDEDDWSKPLPPSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHHYKGSSRGRSKSSRFSGGFGARDYRQSSGASSSSFSSSRASSSRSGGGGHGSSRGFGGGGYGGFYNSDGYGGNYNSQGVDWWGN
Protein: Ubiquitin-conjugating enzyme E2 1
UniProt accession: P21734
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: UBC1, YD9395.10, YDR177W
Length: 215 residues
Disorder content (fraction disordered): 0.10697674418604652
Curated region start positions: 150, 150
Curated region end positions: 172, 172
Curated region terms: disorder, flexible linker
Domain/feature annotations: Ubiquitin Conjugating Enzyme, DNA helicase RuvA subunit, C-terminal domain, Ubiquitin-conjugating enzyme, Fungal ubiquitin-associated domain
Cross-references: BMRB:6202, PDB:1TTE
Sequence:
MSRAKRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFLGPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNISSVTGAICLDILKNAWSPVITLKSALISLQALLQSPEPNDPQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNVEESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDPNDNNTANRIIEELLK
Protein: Protein K7
UniProt accession: P68466
Organism: Vaccinia virus (strain Western Reserve)
Taxonomy: Viruses, Varidnaviria, Bamfordvirae, Nucleocytoviricota, Pokkesviricetes, Chitovirales, Poxviridae, Chordopoxvirinae, Orthopoxvirus, Vaccinia virus
Gene names: K7R, VACWR039
Length: 149 residues
Disorder content (fraction disordered): 0.16778523489932887
Dataset labels: Viral proteins
Curated region start positions: 83, 116, 118, 118
Curated region end positions: 94, 128, 127, 127
Curated region terms: disorder, disorder, disorder, disorder to order
Domain/feature annotations: dsDNA poxvirus, Poxvirus Bcl-2-like proteins
Cross-references: BMRB:15740, PDB:2K36, PDB:3JRV
Sequence:
MATKLDYEDAVFYFVDDDKICSRDSIIDLIDEYITWRNHVIVFNKDITSCGRLYKELMKFDDVAIRYYGIDKINEIVEAMSEGDHYINFTKVHDQESLFATIGICAKITEHWGYKKISESRFQSLGNITDLMTDDNINILILFLEKKLN