LiteFold/DisProt huggingface dataset:
Protein: Uncharacterized protein
UniProt accession: Q87GF9
Organism: Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Vibrionales, Vibrionaceae, Vibrio
Gene names: VPA1357
Length: 1622 residues
Disorder content (fraction disordered): 0.04192355117139334
Curated region start positions: 361, 361, 361, 361, 361
Curated region end positions: 428, 428, 428, 428, 428
Curated region terms: disorder, protein binding, protein binding, molecular function regulator, molecular function regulator
Sequence:
MAYNISLNNITTTTAPVQQELSGISLQTSASALPRVDIQPNVNEHQLPQALSPSDSCLENEESSSQQPEVKKEQAEKKKKVHKKSNKYSNHTKAKGHLAAIAGATTLGAVLAPFTGGLSLLPTAFVVLFGNASALAMYGGSEFVLGQKGPNNQIDDKKDPEANKQPEENKQPEISVPVSPRPIRAQEFRGLDEVNGRREPEPEEKGSRGKGDTFNYSPVFNFNFGDLNFNQFNTQNNTQFNTQNNTDKTNQADTDSSPTLIEQTIEKFGGNPVINVEEITKDVLIRELREQEPLIGPESKVDEMIDALVSFHEQTNEAKLIQVSFESGHKAYIGGIPDTDEQKQTDPIKAEVCVEKAKKQWPEVKPAHRLITTSGNAKIDGNPGYRNARVDVDGQTVGYTRNERGGSQPQSSGVHTLQGSQQPSVEPSPVDPGHGASGAASAQPGGEAKGAQTPSLHTQGEPISTATQTGGAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASDVASAQPGGEAKGTETPSLQTEGESISTSMPTGEEQGVQTGGVKKWPEVAAPQRVITSAGNAKIDGNPGYRNARVDVDGQTVGYTRNERGGSQPQSSGVHTLQGSQQPSVEPSPVDPGHGASGAASAQPGGEAKGAQTPSLHTQGEPISTSMPTGEEQGVQTGGVKKWPEVAAPQRVITSAGNAKIDGNPGYRNARVDVDGQTVGYTRNERSGSQPQSSGVHTLQGSQQPSVEPSPVDPGHGASGAASAQPGGEAKGAQTPGLHTQGEPISTATQTGGAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASDVASAQPGGEAKGTQTPSLQTEGESISTSMPTGEEQGVQTGGVKKWPEVAAPQRVITSAGNAKIDGNPGYRNARVDVDGQTVGYTRNERGGSQPQSSGVHTSQGSQQPGVEPSPVDPGHGASGAASVQPGGEAKGAQTPSLHTQGEPISTATQTGEAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASGAASAQPGGEAKGAQTPSLHTQGEPISTATQTGGAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASDVASAQPGGEAKGAQTPSLHTQGEPISTATQTGGAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASGAASAQPGGEAKGAQTPGLHTQGEPISTATQTGGAQGTQGGEDDGRPQVAQGHNPQGEPASLAKAGTPVDPGHGASDVASAQPGGEAKGTQTPSLQTEGESISTSMPTGEEQGVQTGGVKKWPEVAAPQRVITSAGNAKIDGNPGYRNARVDVDGQTVGYTRNERGGSQPQSSGVHTSQGSQQPGVEPSPVDPGHGASGAASVQPGGEAKGAQTPSLHTQGEPISTATQTGGAQNIQSVTLARADLQQTNVERGRITDVTKLVDVQALASTVAANKSEPERFVSKLHITLKGNSSADSKVGTNQPESLQAWSSNMLSHGPGVKLAQKSLVQNEIELMPQANNGETVKKIEVVSNISGKKWTVSMPAPVLTTQGMASGRGKNYTQGLFHNIRDINQTKRNIELNSTLMESTPKSDVSFVNMGDKVIPIKPAIISNLKLVS
Protein: Islet amyloid polypeptide
UniProt accession: P10997
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: IAPP
Length: 89 residues
Disorder content (fraction disordered): 0.7528089887640449
Curated region start positions: 23, 62, 23, 23, 23, 74, 74, 74, 23
Curated region end positions: 33, 71, 89, 89, 89, 89, 89, 89, 89
Curated region terms: disorder, disorder, disorder, disorder to order, lipid binding, disorder, disorder to order, lipid binding, lipid binding
Domain/feature annotations: Calcitonin / CGRP / IAPP family
Cross-references: BMRB:50007, PDB:6UCJ, PDB:6UCK
Sequence:
MGILKLQVFLIVLSVALNHLKATPIESHQVEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYGKRNAVEVLKREPLNYLPL
Protein: Isoform 6 of Protein quaking
UniProt accession: Q96PU8-9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HKQ, QKI
Length: 319 residues
Disorder content (fraction disordered): 0.3605015673981191
Curated region start positions: 205, 205
Curated region end positions: 319, 319
Curated region terms: disorder, disorder
Sequence:
MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEYPYTLAPATSILEYPIEPSGVLGMAFPTKG
Protein: Uncharacterized protein
UniProt accession: A1B602
Organism: Paracoccus denitrificans (strain Pd 1222)
Taxonomy: Bacteria, Proteobacteria, Alphaproteobacteria, Rhodobacterales, Rhodobacteraceae, Paracoccus
Gene names: Pden_2862
Length: 104 residues
Disorder content (fraction disordered): 0.4230769230769231
Curated region start positions: 1, 80, 1, 1, 1, 1
Curated region end positions: 14, 104, 14, 19, 19, 19
Curated region terms: disorder, disorder, molecular function inhibitor activity, disorder to order, protein binding, disorder
Domain/feature annotations: ATPase inhibitor subunit zeta
Cross-references: BMRB:18018, PDB:2LL0, PDB:5DN6
Sequence:
MTTFDDRERAHEAKFAHDAELNFKAEARRNRLLGEWAAGLLGKTGDDARAYALTVVTSDFDEPGDEDVFRKLAADLEGKADEETIRAKMVELRATAREQIISEI
Protein: Uncharacterized protein
UniProt accession: A0A142G2L5
Organism: Aggregatibacter actinomycetemcomitans
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pasteurellales, Pasteurellaceae, Aggregatibacter
Gene names: FXB68_04315
Length: 181 residues
Disorder content (fraction disordered): 0.8895027624309392
Curated region start positions: 21, 21, 21, 21
Curated region end positions: 181, 181, 181, 181
Curated region terms: disorder, disorder, disorder, protein binding
Cross-references: BMRB:27824
Sequence:
MKKSVLAALVLGVTLSVTGCDDSKTSPQAEQAKTSVSEAKDAVVNAANDVKDATVEAAKDAQNMAADKMVEVKDAISEKMDAMTTQASEMKDAAVEAAKDAKDAAADKMAEVKDAISEKMDAMATQVNEMKDTAAEAVKDAKDAAADKMTEVKDAVSEKMGATATQTNEMKDAVKSETESK
Protein: Uncharacterized protein
UniProt accession: F1NGB1
Organism: Gallus gallus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Archelosauria, Archosauria, Dinosauria, Saurischia, Theropoda, Coelurosauria, Aves, Neognathae, Galloanserae, Galliformes, Phasianidae, Phasianinae, Gallus
Gene names: NUCB2
Length: 455 residues
Disorder content (fraction disordered): 0.5846153846153846
Curated region start positions: 190, 265, 309, 309, 265
Curated region end positions: 455, 284, 334, 334, 284
Curated region terms: disorder, calcium ion binding, calcium ion binding, disorder to order, disorder to order
Domain/feature annotations: EF-hand domain pair, NUCB1-like, N-terminal domain
Sequence:
MKWQSLLPQQCILLIPCLLMALEAVPIDIDKTKVKGEGHVEGEKIENPDTGLYYDEYLRQVIDVLETDKHFREKLQTADIEEIKSGKLSRELDLVSHHVRTRLDELKRQEVARLRMLIKAKMDSVQDTGIDHQALLKQFEHLNHQNPDTFEPKDLDMLIKAATSDLENYDKTRHEEFKKYEMMKEHERREYLKTLDEEKRQREESKFEEMKKKHGDHPKVHHPGSKDQLKEVWEEADGLDPNEFDPKTFFKLHDVNNDRFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDINKDRLVTLEEFLRATEKKEFLEPDSWETLDQQQLFTEDELKEFESHISQQEDELRKKAEELQKQKEELQRQHDQLQAQKQELQQVVKQMEQKKLQQANPPAGPAGELKFQPPGEHKIEEAPKHPAGGDQPLPPGHIQEPAARTDQVHP
Protein: Nucleobindin-2
UniProt accession: P80303
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NEFA, NUCB2
Length: 420 residues
Disorder content (fraction disordered): 0.55
Curated region start positions: 190, 265, 309, 265, 309
Curated region end positions: 420, 282, 334, 282, 334
Curated region terms: disorder, disorder to order, disorder to order, calcium ion binding, calcium ion binding
Domain/feature annotations: EF-hand domain pair, NUCB1-like, N-terminal domain
Sequence:
MRWRTILLQYCFLLITCLLTALEAVPIDIDKTKVQNIHPVESAKIEPPDTGLYYDEYLKQVIDVLETDKHFREKLQKADIEEIKSGRLSKELDLVSHHVRTKLDELKRQEVGRLRMLIKAKLDSLQDIGMDHQALLKQFDHLNHLNPDKFESTDLDMLIKAATSDLEHYDKTRHEEFKKYEMMKEHERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKDQLKEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVEMEEERLRMREHVMNEVDTNKDRLVTLEEFLKATEKKEFLEPDSWETLDQQQFFTEEELKEYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEYHQVIQQMEQKKLQQGIPPSGPAGELKFEPHI
Protein: DELLA protein SLR1
UniProt accession: Q7G7J6
Organism: Oryza sativa subsp. japonica
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, Liliopsida, Poales, Poaceae, BOP clade, Oryzoideae, Oryzeae, Oryzinae, Oryza, Oryza sativa
Gene names: GAI, LOC_Os03g49990, OSJNBb0022E02.5, Os03g0707600, OsJ_12286, SLR1
Length: 625 residues
Disorder content (fraction disordered): 0.136
Curated region start positions: 28, 28, 28, 28, 28, 28, 28
Curated region end positions: 112, 112, 112, 112, 112, 112, 112
Curated region terms: disorder, disorder, disorder, protein binding, disorder to order, disorder to order, protein binding
Domain/feature annotations: GRAS domain family, Transcriptional regulator DELLA protein N terminal
Sequence:
MKREYQEAGGSSGGGSSADMGSCKDKVMAGAAGEEEDVDELLAALGYKVRSSDMADVAQKLEQLEMAMGMGGVSAPGAADDGFVSHLATDTVHYNPSDLSSWVESMLSELNAPLPPIPPAPPAARHASTSSTVTGGGGSGFFELPAAADSSSSTYALRPISLPVVATADPSAADSARDTKRMRTGGGSTSSSSSSSSSLGGGASRGSVVEAAPPATQGAAAANAPAVPVVVVDTQEAGIRLVHALLACAEAVQQENFAAAEALVKQIPTLAASQGGAMRKVAAYFGEALARRVYRFRPADSTLLDAAFADLLHAHFYESCPYLKFAHFTANQAILEAFAGCHRVHVVDFGIKQGMQWPALLQALALRPGGPPSFRLTGVGPPQPDETDALQQVGWKLAQFAHTIRVDFQYRGLVAATLADLEPFMLQPEGEADANEEPEVIAVNSVFELHRLLAQPGALEKVLGTVHAVRPRIVTVVEQEANHNSGSFLDRFTESLHYYSTMFDSLEGGSSGQAELSPPAAGGGGGTDQVMSEVYLGRQICNVVACEGAERTERHETLGQWRNRLGRAGFEPVHLGSNAYKQASTLLALFAGGDGYRVEEKEGCLTLGWHTRPLIATSAWRVAAA
Protein: C-X-C chemokine receptor type 1
UniProt accession: P25024
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CMKAR1, CXCR1, IL8RA
Length: 350 residues
Disorder content (fraction disordered): 0.15428571428571428
Curated region start positions: 1, 326, 1, 1, 1, 1
Curated region end positions: 28, 350, 29, 29, 29, 29
Curated region terms: disorder, disorder, disorder to order, disorder, protein binding, protein binding
Domain/feature annotations: 7 transmembrane receptor (rhodopsin family)
Cross-references: BMRB:18170, PDB:2LNL
Sequence:
MSNITDPQMWDFDDLNFTGMPPADEDYSPCMLETETLNKYVVIIAYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFVCLGCWGLSMNLSLPFFLFRQAYHPNNSSPVCYEVLGNDTAKWRMVLRILPHTFGFIVPLFVMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQESCERRNNIGRALDATEILGFLHSCLNPIIYAFIGQNFRHGFLKILAMHGLVSKEFLARHRVTSYTSSSVNVSSNL
Protein: Carbamoyl-phosphate synthase [ammonia], mitochondrial
UniProt accession: P31327
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CPS1
Length: 1500 residues
Disorder content (fraction disordered): 0.050666666666666665
Curated region start positions: 779, 562, 779, 788, 585, 779, 779, 562
Curated region end positions: 792, 623, 784, 792, 623, 784, 792, 623
Curated region terms: disorder, disorder to order, potassium ion binding, small molecule binding, small molecule binding, metal ion binding, disorder to order, disorder
Domain/feature annotations: Glutamine amidotransferase class-I, Carbamoyl-phosphate synthase small chain, CPSase domain, MGS-like domain, Carbamoyl-phosphate synthase L chain, ATP binding domain, Carbamoyl-phosphate synthase L chain, ATP binding domain, Carbamoyl-phosphate synthetase large chain, oligomerisation domain, Carbamoyl phosphate synthase preATP-grasp domain, Carbamoyl phosphate synthase preATP-grasp domain
Cross-references: PDB:5DOT, PDB:5DOU
Sequence:
MTRILTAFKVVRTLKTGFGFTNVTAHQKWKFSRPGIRLLSVKAQTAHIVLEDGTKMKGYSFGHPSSVAGEVVFNTGLGGYPEAITDPAYKGQILTMANPIIGNGGAPDTTALDELGLSKYLESNGIKVSGLLVLDYSKDYNHWLATKSLGQWLQEEKVPAIYGVDTRMLTKIIRDKGTMLGKIEFEGQPVDFVDPNKQNLIAEVSTKDVKVYGKGNPTKVVAVDCGIKNNVIRLLVKRGAEVHLVPWNHDFTKMEYDGILIAGGPGNPALAEPLIQNVRKILESDRKEPLFGISTGNLITGLAAGAKTYKMSMANRGQNQPVLNITNKQAFITAQNHGYALDNTLPAGWKPLFVNVNDQTNEGIMHESKPFFAVQFHPEVTPGPIDTEYLFDSFFSLIKKGKATTITSVLPKPALVASRVEVSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMNPNIASVQTNEVGLKQADTVYFLPITPQFVTEVIKAEQPDGLILGMGGQTALNCGVELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNVVSGKTSACFEPSLDYMVTKIPRWDLDRFHGTSSRIGSSMKSVGEVMAIGRTFEESFQKALRMCHPSIEGFTPRLPMNKEWPSNLDLRKELSEPSSTRIYAIAKAIDDNMSLDEIEKLTYIDKWFLYKMRDILNMEKTLKGLNSESMTEETLKRAKEIGFSDKQISKCLGLTEAQTRELRLKKNIHPWVKQIDTLAAEYPSVTNYLYVTYNGQEHDVNFDDHGMMVLGCGPYHIGSSVEFDWCAVSSIRTLRQLGKKTVVVNCNPETVSTDFDECDKLYFEELSLERILDIYHQEACGGCIISVGGQIPNNLAVPLYKNGVKIMGTSPLQIDRAEDRSIFSAVLDELKVAQAPWKAVNTLNEALEFAKSVDYPCLLRPSYVLSGSAMNVVFSEDEMKKFLEEATRVSQEHPVVLTKFVEGAREVEMDAVGKDGRVISHAISEHVEDAGVHSGDATLMLPTQTISQGAIEKVKDATRKIAKAFAISGPFNVQFLVKGNDVLVIECNLRASRSFPFVSKTLGVDFIDVATKVMIGENVDEKHLPTLDHPIIPADYVAIKAPMFSWPRLRDADPILRCEMASTGEVACFGEGIHTAFLKAMLSTGFKIPQKGILIGIQQSFRPRFLGVAEQLHNEGFKLFATEATSDWLNANNVPATPVAWPSQEGQNPSLSSIRKLIRDGSIDLVINLPNNNTKFVHDNYVIRRTAVDSGIPLLTNFQVTKLFAEAVQKSRKVDSKSLFHYRQYSAGKAA
Protein: Signal transducer and activator of transcription 3
UniProt accession: P40763
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: APRF, STAT3
Length: 770 residues
Disorder content (fraction disordered): 0.04415584415584416
Dataset labels: Cancer-related proteins, Condensates-related proteins
Curated region start positions: 690, 689
Curated region end positions: 722, 702
Curated region terms: disorder, disorder
Domain/feature annotations: SH2 domain, STAT transcription factor, coiled-coil domain, STAT protein, DNA binding domain, STAT protein, protein interaction domain, Signal transducer and activator of transcription, linker domain
Cross-references: PDB:6QHD, PDB:6TLC
Sequence:
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
Protein: Sll1515 protein
UniProt accession: P72975
Organism: Synechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomy: Bacteria, Cyanobacteria, Synechococcales, Merismopediaceae, Synechocystis, unclassified Synechocystis
Gene names: sll1515
Length: 149 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 149, 149, 149, 149, 149, 149, 149, 149
Curated region terms: disorder, disorder, disorder, pre-molten globule, molecular function inhibitor activity, protein binding, protein binding, molecular function inhibitor activity
Domain/feature annotations: Domain of unknown function (DUF4278)
Sequence:
MQLSYRGVKYDYNPPKVETEVLGLAGSYRGLDYRFRRTTTKNVIQPNVNLTYRGVSFNPAQDLQPELYTANKKVEVAAAPSQISFQDRVRARLHSKTQAIKKRQQSLLVRLAEEIGLSGDQAVNSAVRIQGKVLANFRSDYASQGVAMS
Protein: GDP-mannose 4,6-dehydratase
UniProt accession: P0AC88
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW2038, b2053, gmd, yefA, yefN
Length: 373 residues
Disorder content (fraction disordered): 0.0938337801608579
Curated region start positions: 35, 359
Curated region end positions: 55, 372
Curated region terms: disorder, disorder
Domain/feature annotations: GDP-mannose 4,6 dehydratase
Cross-references: PDB:1DB3
Sequence:
MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVAKLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES
Protein: Thymidine kinase
UniProt accession: P0DTH5
Organism: Human herpesvirus 1 (strain 17)
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Peploviricota, Herviviricetes, Herpesvirales, Herpesviridae, Alphaherpesvirinae, Simplexvirus
Gene names: TK, UL23
Length: 376 residues
Disorder content (fraction disordered): 0.1196808510638298
Dataset labels: Viral proteins
Curated region start positions: 1
Curated region end positions: 45
Curated region terms: disorder
Domain/feature annotations: Thymidine kinase from herpesvirus
Cross-references: PDB:1OF1
Sequence:
MASYPCHQHASAFDQAARSRGHNNRRTALRPRRQQKATEVRLEQKMPTLLRVYIDGPHGMGKTTTTQLLVALGSRDDIVYVPEPMTYWRVLGASETIANIYTTQHRLDQGEISAGDAAVVMTSAQITMGMPYAVTDAVLAPHIGGEAGSSHAPPPALTLIFDRHPIAALLCYPAARYLMGSMTPQAVLAFVALIPPTLPGTNIVLGALPEDRHIDRLAKRQRPGERLDLAMLAAIRRVYGLLANTVRYLQGGGSWREDWGQLSGAAVPPQGAEPQSNAGPRPHIGDTLFTLFRAPELLAPNGDLYNVFAWALDVLAKRLRPMHVFILDYDQSPAGCRDALLQLTSGMVQTHVTTPGSIPTICDLARTFAREMGEAN
Protein: Serine/threonine-protein kinase PAK 1
UniProt accession: Q13153
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PAK1
Length: 545 residues
Disorder content (fraction disordered): 0.4844036697247706
Dataset labels: NDDs-related proteins
Curated region start positions: 492, 1, 186, 150, 83, 83, 47, 150, 182
Curated region end positions: 545, 56, 199, 248, 137, 137, 51, 248, 203
Curated region terms: disorder, disorder, protein binding, flexible linker, disorder, disorder, localization, disorder, protein binding
Domain/feature annotations: Protein kinase domain, P21-Rho-binding domain
Cross-references: PDB:1ZSG
Sequence:
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH
Protein: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, apicoplast
UniProt accession: Q8I295
Organism: Plasmodium falciparum (isolate 3D7)
Taxonomy: Eukaryota, Sar, Alveolata, Apicomplexa, Aconoidasida, Haemosporida, Plasmodiidae, Plasmodium, Plasmodium (Laverania)
Gene names: IspH, LytB, PF3D7_0104400
Length: 535 residues
Disorder content (fraction disordered): 0.405607476635514
Curated region start positions: 1
Curated region end positions: 217
Curated region terms: disorder
Domain/feature annotations: LytB protein
Cross-references: PDB:4N7B
Sequence:
MSVTTFCSLKKTDKCNIYISKRAFSVFLFYLFFFLFFHFYFLCSSSFAVIIHESEKRKNIMRRKRSILQIFENSIKSKEGKCNFTKRYITHYYNIPLKIKKHDLPSVIKYFSHKPNGKHNYVTNMITQKNRKSFLFFFFLYNKYFFGKQEQIRKMNYHEEMNKINIKNDGNRKIYMYPKNDIHEEDGDHKNDVEINQKRNEQNCKSFNDEKNENARDPNKILYLINPRGFCKGVSRAIETVEECLKLFKPPIYVKHKIVHNDIVCKKLEKEGAIFIEDLNDVPDGHILIYSAHGISPQIREIAKKKKLIEIDATCPLVNKVHVYVQMKAKENYDIILIGYKNHVEVIGTYNEAPHCTHIVENVNDVDKLNFPLNKKLFYVTQTTLSMDDCALIVQKLKNKFPHIETIPSGSICYATTNRQTALNKICTKCDLTIVVGSSSSSNAKKLVYSSQIRNVPAVLLNTVHDLDQQILKNVNKIALTSAASTPEQETQKFVNLLTNPPFNYTLQNFDGAHENVPKWKLPKNLLHMIKEREK
Protein: C-X-C chemokine receptor type 1
UniProt accession: P21109
Organism: Oryctolagus cuniculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Lagomorpha, Leporidae, Oryctolagus
Gene names: CXCR1, IL8RA
Length: 355 residues
Disorder content (fraction disordered): 0.09577464788732394
Curated region start positions: 11, 11, 11
Curated region end positions: 44, 44, 44
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: 7 transmembrane receptor (rhodopsin family)
Sequence:
MEVNVWNMTDLWTWFEDEFANATGMPPVEKDYSPCLVVTQTLNKYVVVVIYALVFLLSLLGNSLVMLVILYSRSNRSVTDVYLLNLAMADLLFALTMPIWAVSKEKGWIFGTPLCKVVSLVKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRHLVKFICLGIWALSLILSLPFFLFRQVFSPNNSSPVCYEDLGHNTAKWRMVLRILPHTFGFILPLLVMLFCYGFTLRTLFQAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTHVIQETCQRRNDIDRALDATEILGFLHSCLNPIIYAFIGQNFRNGFLKMLAARGLISKEFLTRHRVTSYTSSSTNVPSNL
Protein: Oxygen-independent coproporphyrinogen III oxidase
UniProt accession: P32131
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3838, b3867, hemN, yihJ
Length: 457 residues
Disorder content (fraction disordered): 0.028446389496717725
Curated region start positions: 445
Curated region end positions: 457
Curated region terms: disorder
Domain/feature annotations: Radical SAM superfamily, HemN C-terminal domain
Cross-references: PDB:1OLT
Sequence:
MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQAVARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAGRHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLRAEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAFLTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGDCYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQWDLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARMQQFSRVI
Protein: Rhodopsin kinase GRK1
UniProt accession: P28327
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: GRK1, RHOK
Length: 561 residues
Disorder content (fraction disordered): 0.35650623885918004
Curated region start positions: 25, 475, 1
Curated region end positions: 181, 493, 29
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Protein kinase domain, Regulator of G protein signaling domain
Cross-references: EMDB:23978, PDB:3C4Y, PDB:7MT9
Sequence:
MDFGSLETVVANSAFIAARGSFDASSGPASRDRKYLARLKLPPLSKCEALRESLDLGFEGMCLEQPIGKRLFQQFLRTHEQHGPALQLWKDIEDYDTADDALRPQKAQALRAAYLEPQAQLFCSFLDAETVARARAGAGDGLFQPLLRAVLAHLGQAPFQEFLDSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGRGGFGEVFACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILAKVHSRFIVSLAYAFETKTDLCLVMTIMNGGDIRYHIYNVDEDNPGFQEPRAIFYTAQIVSGLEHLHQRNIIYRDLKPENVLLDDDGNVRISDLGLAVELKAGQTKTKGYAGTPGFMAPELLLGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKQRVLEQAVTYPDKFSPASKDFCEALLQKDPEKRLGFRDGSCDGLRTHPLFRDISWRQLEAGMLTPPFVPDSRTVYAKNIQDVGAFSTVKGVAFEKADTEFFQEFASGTCPIPWQEEMIETGVFGDLNVWRPDGQMPDDMKGVSGQEAAPSSKSGMCVLS
Protein: L-threonine dehydratase biosynthetic IlvA
UniProt accession: P04968
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3745, b3772, ilvA
Length: 514 residues
Disorder content (fraction disordered): 0.0311284046692607
Curated region start positions: 481
Curated region end positions: 496
Curated region terms: disorder
Domain/feature annotations: Pyridoxal-phosphate dependent enzyme, C-terminal regulatory domain of Threonine dehydratase, C-terminal regulatory domain of Threonine dehydratase
Cross-references: PDB:1TDJ
Sequence:
MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHPMVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELGEQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEERKEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRFLNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAFRFFLAG
Protein: ORF7a protein
UniProt accession: P59635
Organism: Severe acute respiratory syndrome coronavirus
Taxonomy: Viruses, Riboviria, Orthornavirae, Pisuviricota, Pisoniviricetes, Nidovirales, Cornidovirineae, Coronaviridae, Orthocoronavirinae, Betacoronavirus, Sarbecovirus
Gene names: 7a
Length: 122 residues
Disorder content (fraction disordered): 0.11475409836065574
Dataset labels: Viral proteins
Curated region start positions: 81
Curated region end positions: 94
Curated region terms: disorder
Domain/feature annotations: Betacoronavirus NS7A protein
Cross-references: PDB:1YO4
Sequence:
MKIILFLTLIVFTSCELYHYQECVRGTTVLLKEPCPSGTYEGNSPFHPLADNKFALTCTSTHFAFACADGTRHTYQLRARSVSPKLFIRQEEVQQELYSPLFLIVAALVFLILCFTIKRKTE