LiteFold/DisProt huggingface dataset:
Protein: Transcription factor GAGA
UniProt accession: Q08605
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: Adf-2, CG33261, GAGA, Nc70F, TFGAGA, Trl
Length: 581 residues
Disorder content (fraction disordered): 0.2495697074010327
Curated region start positions: 310, 310, 310, 310, 310, 281, 281, 281, 281, 368, 368, 368, 368
Curated region end positions: 335, 335, 335, 335, 335, 348, 348, 348, 348, 444, 444, 444, 444
Curated region terms: disorder, molecular function activator activity, disorder to order, nucleic acid binding, protein binding, disorder, molecular function activator activity, nucleic acid binding, protein binding, disorder, molecular function activator activity, nucleic acid binding, protein binding
Domain/feature annotations: Classic Zinc Finger, Potassium Channel Kv1.1; Chain A, BTB/POZ domain, GAGA factor
Cross-references: PDB:1YUI
Sequence:
MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEITPAQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKPGVKKEKKTTSGKKSSSGSSGSGSGALSSSGSVPQVQTVQSLHTLQGVQVKKDPDAQQQQQQQQQQQQQQQQAMTVSGATGGQVQQQVQQVQQQVQQQQQQQQQQQQQLQHHQIIDSSGNITTATTSAQAAAAAQQQAAGQQQQLVAQSDGSESGAPLSIAQVQTLQGHQIIGNLNQVNMTDFQQQQPQQQQQQQQQQQQQQQQQQQTQQTL
Protein: Beta-casein
UniProt accession: P02666
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: CSN2
Length: 224 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 25, 224, 224, 224, 224, 224, 224, 224, 224, 224
Curated region terms: disorder, disorder, metal ion binding, ion binding, disorder, metal ion binding, ion binding, disorder, disorder to molten globule, calcium ion binding
Domain/feature annotations: Casein
Sequence:
MKVLILACLVALALARELEELNVPGEIVESLSSSEESITRINKKIEKFQSEEQQQTEDELQDKIHPFAQTQSLVYPFPGPIPNSLPQNIPPLTQTPVVVPPFLQPEVMGVSKVKEAMAPKHKEMPFPKYPVEPFTESQSLTLTDVENLHLPLPLLQSWMHQPHQPLPPTVMFPPQSVLSLSQSKVLPVPQKAVPYPQRDMPIQAFLLYQEPVLGPVRGPFPIIV
Protein: Bone sialoprotein 2
UniProt accession: P21815
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BNSP, IBSP
Length: 317 residues
Disorder content (fraction disordered): 1
Dataset labels: Extracellular matrix proteins
Curated region start positions: 1, 1, 1, 285, 285, 285, 1, 1, 258, 258, 1
Curated region end positions: 317, 317, 317, 289, 289, 289, 317, 317, 317, 317, 317
Curated region terms: disorder, small molecule binding, protein binding, protein binding, protein binding, protein binding, protein binding, small molecule binding, disorder, protein binding, molecular adaptor activity
Domain/feature annotations: Bone sialoprotein II (BSP-II)
Sequence:
MKTALILLSILGMACAFSMKNLHRRVKIEDSEENGVFKYRPRYYLYKHAYFYPHLKRFPVQGSSDSSEENGDDSSEEEEEEEETSNEGENNEESNEDEDSEAENTTLSATTLGYGEDATPGTGYTGLAAIQLPKKAGDITNKATKEKESDEEEEEEEEGNENEESEAEVDENEQGINGTSTNSTEAENGNGSSGGDNGEEGEEESVTGANAEDTTETGRQGKGTSKTTTSPNGGFEPTTPPQVYRTTSPPFGKTTTVEYEGEYEYTGANEYDNGYEIYESENGEPRGDNYRAYEDEYSYFKGQGYDGYDGQNYYHHQ
Protein: Calreticulin
UniProt accession: P27797
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CALR, CRTC
Length: 417 residues
Disorder content (fraction disordered): 0.9592326139088728
Dataset labels: Extracellular matrix proteins, Cancer-related proteins, Autophagy-related proteins
Curated region start positions: 367, 367, 18, 18, 308, 18, 18, 199, 199, 199, 199, 199, 199, 18, 261, 120, 168, 219
Curated region end positions: 417, 417, 417, 307, 417, 417, 417, 204, 204, 204, 204, 204, 204, 417, 278, 146, 182, 226
Curated region terms: disorder, disorder, molten globule, order, molten globule, molten globule, molten globule, selective autophagy, protein binding, protein binding, protein binding, protein binding, protein binding, nuclear export signal receptor activity, complement component C1q complex binding, complement component C1q complex binding, complement component C1q complex binding, complement component C1q complex binding
Domain/feature annotations: Calreticulin/calnexin, P domain, 2.60.120.200, 2.60.120.200, Calreticulin family, Calreticulin family
Sequence:
MLLSVPLLLGLLGLAVAEPAVYFKEQFLDGDGWTSRWIESKHKSDFGKFVLSSGKFYGDEEKDKGLQTSQDARFYALSASFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPNSLDQTDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDASKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDPSIYAYDNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDEL
Protein: E3 ubiquitin-protein ligase Mdm2
UniProt accession: Q00987
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MDM2
Length: 491 residues
Disorder content (fraction disordered): 0.4521384928716904
Dataset labels: Cancer-related proteins
Curated region start positions: 1, 210, 215, 335, 1
Curated region end positions: 24, 304, 300, 437, 24
Curated region terms: disorder, disorder, disorder, disorder, flexible N-terminal tail
Domain/feature annotations: SWIB/MDM2 domain, Zinc/RING finger domain, C3HC4 (zinc finger), Zn-finger in Ran binding protein and others, SWIB/MDM2 domain, Zinc finger, C3HC4 type (RING finger)
Cross-references: BMRB:51334, BMRB:6612, PDB:1Z1M, PDB:4XXB
Sequence:
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Protein: Tumor suppressor ARF
UniProt accession: Q64364
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Cdkn2a
Length: 169 residues
Disorder content (fraction disordered): 0.21893491124260356
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 37, 37, 37, 37, 37
Curated region terms: disorder, protein binding, disorder, disorder to order, protein binding
Domain/feature annotations: Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus
Cross-references: PDB:1HN3
Sequence:
MGRRFLVTVRIQRAGRPLQERVFLVKFVRSRRPRTASCALAFVNMLLRLERILRRGPHRNPGPGDDDGQRSRSSSSAQLRCRFELRGPHYLLPPGARRSAGRLPGHAGGAARVRGSAGCARCLGSPAARLGPRAGTSRHRAIFAFRWVLFVFRWVVFVYRWERRPDRRA
Protein: Deoxyuridine 5'-triphosphate nucleotidohydrolase
UniProt accession: P06968
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3615, b3640, dnaS, dut, sof
Length: 152 residues
Disorder content (fraction disordered): 0.10526315789473684
Curated region start positions: 137, 138
Curated region end positions: 152, 152
Curated region terms: disorder, disorder
Domain/feature annotations: 2.70.40.10, dUTPase
Cross-references: PDB:1DUP
Sequence:
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
Protein: Histo-blood group ABO system transferase
UniProt accession: P16442
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ABO
Length: 354 residues
Disorder content (fraction disordered): 0.04519774011299435
Curated region start positions: 179, 179
Curated region end positions: 194, 194
Curated region terms: disorder, entropic chain
Domain/feature annotations: Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A, Glycosyltransferase family 6
Cross-references: PDB:1LZ0
Sequence:
MAEVLRTLAGKPKCHALRPMILFLIMLVLVLFGYGVLSPRSLMPGSLERGFCMAVREPDHLQRVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYLGGFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPKNHQAVRNP
Protein: Catenin beta-1
UniProt accession: Q02248
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Catnb, Ctnnb1
Length: 781 residues
Disorder content (fraction disordered): 0.3213828425096031
Curated region start positions: 664, 664, 664, 1, 672, 17, 17
Curated region end positions: 781, 781, 781, 133, 781, 48, 48
Curated region terms: disorder, molecular function activator activity, nucleic acid binding, disorder, disorder, disorder, disorder
Domain/feature annotations: Leucine-rich Repeat Variant, Armadillo/beta-catenin-like repeat, Armadillo/beta-catenin-like repeat, Armadillo/beta-catenin-like repeat, Armadillo/beta-catenin-like repeat
Cross-references: PDB:3OUW
Sequence:
MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEALGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL
Protein: Colicin-E9
UniProt accession: P09883
Organism: Escherichia coli
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: cei, col
Length: 582 residues
Disorder content (fraction disordered): 0.14261168384879724
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 1, 1, 2, 2, 54, 32, 34, 32, 33, 2, 32
Curated region end positions: 83, 61, 18, 18, 63, 47, 46, 47, 44, 18, 47
Curated region terms: disorder, disorder, disorder, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, disorder to order
Domain/feature annotations: Colicin/pyocin, DNase domain, Helix Hairpins, Colicin-like bacteriocin tRNase domain, Coiled-coil receptor-binding R-domain of colicin E2, Colicin/Pyocin-S2, DNase domain
Cross-references: PDB:2IVZ, PDB:3O0E
Sequence:
MSGGDGRGHNTGAHSTSGNINGGPTGIGVSGGASDGSGWSSENNPWGGGSGSGIHWGGGSGRGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISASELSAAIAGIIAKLKKVNLKFTPFGVVLSSLIPSEIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNDSTPAVQTLSPGVTNNTDKDVRPAGFTQGGNTRDAVIRFPKDSGHNAVYVSVSDVLSPDQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDAAAKEKSDADAALSAAQERRKQKENKEKDAKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKSFDDFRKAVWEEVSKDPELSKNLNPSNKSSVSKGYSPFTPKNQQVGGRKVYELHHDKPISQGGEVYDMDNIRVTTPKRHIDIHRGK
Protein: Nuclear receptor coactivator 3
UniProt accession: Q9Y6Q9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AIB1, BHLHE42, NCOA3, RAC3, TRAM1
Length: 1424 residues
Disorder content (fraction disordered): 0.04985955056179775
Dataset labels: Condensates-related proteins
Curated region start positions: 1018, 1045, 1018, 1018, 1045
Curated region end positions: 1088, 1085, 1088, 1045, 1085
Curated region terms: disorder, disorder to order, protein binding, disorder, protein binding
Domain/feature annotations: Helix-loop-helix DNA-binding domain, PAS domain, PAS domain, PAS fold, Nuclear receptor coactivator, DUF1518, Nuclear receptor coactivator, Steroid receptor coactivator, PAS domain, Domain of unknown function (DUF4927), Unstructured region on nuclear receptor coactivator protein, Nuclear receptor coactivators bHLH domain
Cross-references: PDB:1KBH
Sequence:
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDIDNFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQALDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNGVSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGEDLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRCIQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDRHGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLADPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNIMISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLSTLSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKESSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVSSSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGNVVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQEKDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLKSSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGSSMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPTLPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQVSHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPELVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMNQMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
Protein: Calmodulin
UniProt accession: P62152
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG8472, Cam
Length: 149 residues
Disorder content (fraction disordered): 0.06711409395973154
Curated region start positions: 74
Curated region end positions: 83
Curated region terms: disorder
Domain/feature annotations: EF-hand, EF-hand, EF-hand, EF-hand domain pair, EF-hand domain pair
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
Protein: Leukotoxin
UniProt accession: P16535
Organism: Mannheimia haemolytica
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pasteurellales, Pasteurellaceae, Mannheimia
Gene names: lktA
Length: 953 residues
Disorder content (fraction disordered): 0.07345225603357818
Dataset labels: Unicellular toxins and antitoxins, Bacterial virulence-related proteins
Curated region start positions: 884, 884, 884, 884, 884
Curated region end positions: 953, 953, 953, 953, 953
Curated region terms: disorder, disorder to order, lipid binding, localization, disorder
Domain/feature annotations: Serralysin-like metalloprotease, C-terminal, RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), N-terminal domain in RTX protein, RTX C-terminal domain
Sequence:
MGTRLTTLSNGLKNTLTATKSGLHKAGQSLTQAGSSLKTGAKKIILYIPQNYQYDTEQGNGLQDLVKAAEELGIEVQREERNNIATAQTSLGTIQTAIGLTERGIVLSAPQIDKLLQKTKAGQALGSAESIVQNANKAKTVLSGIQSILGSVLAGMDLDEALQNNSNQHALAKAGLELTNSLIENIANSVKTLDEFGEQISQFGSKLQNIKGLGTLGDKLKNIGGLDKAGLGLDVISGLLSGATAALVLADKNASTAKKVGAGFELANQVVGNITKAVSSYILAQRVAAGLSSTGPVAALIASTVSLAISPLAFAGIADKFNHAKSLESYAERFKKLGYDGDNLLAEYQRGTGTIDASVTAINTALAAIAGGVSAAAAGSVIASPIALLVSGITGVISTILQYSKQAMFEHVANKIHNKIVEWEKNNHGKNYFENGYDARYLANLQDNMKFLLNLNKELQAERVIAITQQQWDNNIGDLAGISRLGEKVLSGKAYVDAFEEGKHIKADKLVQLDSANGIIDVSNSGKAKTQHILFRTPLLTPGTEHRERVQTGKYEYITKLNINRVDSWKITDGAASSTFDLTNVVQRIGIELDNAGNVTKTKETKIIAKLGEGDDNVFVGSGTTEIDGGEGYDRVHYSRGNYGALTIDATKETEQGSYTVNRFVETGKALHEVTSTHTALVGNREEKIEYRHSNNQHHAGYYTKDTLKAVEEIIGTSHNDIFKGSKFNDAFNGGDGVDTIDGNDGNDRLFGGKGDDILDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRKGDGNDIITDSDGNDKLSFSDSNLKDLTFEKVKHNLVITNSKKEKVTIQNWFREADFAKEVPNYKATKDEKIEEIIGQNGERITSKQVDDLIAKGNGKITQDELSKVVDNYELLKHSKNVTNSLDKLISSVSAFTSSNDSRNVLVAPTSMLDQSLSSLQFARAA
Protein: Acetylcholinesterase
UniProt accession: P07140
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: Ace, CG17907
Length: 649 residues
Disorder content (fraction disordered): 0.0662557781201849
Curated region start positions: 142, 613
Curated region end positions: 173, 623
Curated region terms: disorder, disorder
Domain/feature annotations: Carboxylesterase family
Cross-references: PDB:1QON
Sequence:
MAISCRQSRVLPMSLPLPLTIPLPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGREVHVYTGIPYAKPPVEDLRFRKPVPAEPWHGVLDATGLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGANGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVASFQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAGSSSVNAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNASMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDILMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLEIMNNIFGKATQAEREAIIFQYTSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGEWMGVLHGDEIEYFFGQPLNNSLQYRPVERELGKRMLSAVIEFAKTGNPAQDGEEWPNFSKEDPVYYIFSTDDKIEKLARGPLAARCSFWNDYLPKVRSWAGTCDGDSGSASISPRLQLLGIAALIYICAALRTKRVF
Protein: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma
UniProt accession: P04972
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: PDE6G, PDEG
Length: 87 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 46, 46, 46, 46
Curated region end positions: 87, 87, 87, 87, 87, 87, 87, 87, 87, 87, 87, 87, 21, 21, 21, 78, 78, 78, 78
Curated region terms: disorder, ion binding, disorder, disorder to pre-molten globule, ion binding, disorder, ion binding, disorder, ion binding, disorder, molecular adaptor activity, protein binding, disorder, molecular adaptor activity, protein binding, disorder, molecular adaptor activity, disorder to order, protein binding
Domain/feature annotations: Retinal cGMP phosphodiesterase, gamma subunit, Retinal cGMP phosphodiesterase, gamma subunit
Cross-references: PDB:2JU4
Sequence:
MNLEPPKAEIRSATRVMGGPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVICPWEAFNHLELHELAQYGII
Protein: Bifunctional ligase/repressor BirA
UniProt accession: P06709
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3941, b3973, bioR, birA, dhbB
Length: 321 residues
Disorder content (fraction disordered): 0.07165109034267912
Curated region start positions: 212, 212, 212, 212
Curated region end positions: 223, 223, 234, 234
Curated region terms: disorder, nucleic acid binding, disorder, nucleic acid binding
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Bira Bifunctional Protein; Domain 2, 2.30.30.100, Biotin protein ligase C terminal domain, Biotin/lipoate A/B protein ligase family, HTH domain
Sequence:
MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELKSGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEVLRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK
Protein: Chemotaxis protein CheW
UniProt accession: Q56311
Organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomy: Bacteria, Thermotogae, Thermotogales, Thermotogaceae, Thermotoga
Gene names: TM_0701, cheW
Length: 151 residues
Disorder content (fraction disordered): 0.17880794701986755
Curated region start positions: 37, 109
Curated region end positions: 49, 122
Curated region terms: disorder, disorder
Domain/feature annotations: CheA-289, Domain 4, SH3 Domains, CheW-like domain
Cross-references: PDB:1K0S
Sequence:
MKTLADALKEFEVLSFEIDEQALAFDVDNIEMVIEKSDITPVPKSRHFVEGVINLRGRIIPVVNLAKILGISFDEQKMKSIIVARTKDVEVGFLVDRVLGVLRITENQLDLTNVSDKFGKKSKGLVKTDGRLIIYLDIDKIIEEITVKEGV
Protein: Putative tyrosine-protein phosphatase auxilin
UniProt accession: Q27974
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: DNAJC6
Length: 910 residues
Disorder content (fraction disordered): 0.2934065934065934
Curated region start positions: 547, 547, 547, 547, 547, 547
Curated region end positions: 813, 813, 813, 813, 813, 813
Curated region terms: disorder, molecular adaptor activity, protein binding, disorder, molecular adaptor activity, protein binding
Domain/feature annotations: DnaJ domain, Protein tyrosine phosphatase superfamily, 2.60.40.1110, C2 domain of PTEN tumour-suppressor protein
Sequence:
MDSSGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDSVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAVRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPVPFFNKQRNGCRPYCDVLIGETKIYTTCADFERMKEYRVQDGKIFIPLSITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVMELTPPWEHYCTKDVNPSILFSSHQEHQDTLVLGGQAPIDIPPDNPRHFGQGGFFSTLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHAARKPSKKQQEPAAPAPPEDVDLLGLEGSAVSKNFSSPAAPPSNSELLSDLFGGGGAAGPVQSGQSGVDDVFHPSGPTSTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTASASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGAWDWHTKPGGFGMGSKSAATSPTGSSHGTPTHQNKPQTLDPFADLGTLGGSSFASKPSTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGGYNWQQTQSKPQSSMPHSSPQNRPNYNVSFSSMPGGQNERGKAAANLEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY
Protein: Glycyl-glycine endopeptidase LytM
UniProt accession: O33599
Organism: Staphylococcus aureus (strain NCTC 8325)
Taxonomy: Bacteria, Firmicutes, Bacilli, Bacillales, Staphylococcaceae, Staphylococcus
Gene names: SAOUHSC_00248, lytM
Length: 316 residues
Disorder content (fraction disordered): 0.3037974683544304
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 26, 147, 108, 108, 147
Curated region end positions: 44, 182, 184, 184, 182
Curated region terms: disorder, disorder, disorder, flexible linker, flexible linker
Domain/feature annotations: Glucose Permease (Domain IIA), 2.40.50.290, Peptidase family M23
Cross-references: BMRB:51662, PDB:1QWY
Sequence:
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR