LiteFold/DisProt huggingface dataset:
Protein: Cell division cycle protein 16 homolog
UniProt accession: Q13042
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC6, CDC16
Length: 620 residues
Disorder content (fraction disordered): 0.2032258064516129
Curated region start positions: 96, 96, 528, 94, 528, 534
Curated region end positions: 126, 123, 620, 126, 620, 620
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Anaphase-promoting complex, cyclosome, subunit 3, Tetratricopeptide repeat
Cross-references: PDB:4UI9, PDB:5G05
Sequence:
MNLERLRKRVRQYLDQQQYQSALFWADKVASLSREEPQDIYWLAQCLYLTAQYHRAAHALRSRKLDKLYEACRYLAARCHYAAKEHQQALDVLDMEEPINKRLFEKYLKDESGFKDPSSDWEMSQSSIKSSICLLRGKIYDALDNRTLATYSYKEALKLDVYCFEAFDLLTSHHMLTAQEEKELLESLPLSKLCNEEQELLRFLFENKLKKYNKPSETVIPESVDGLQENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYIGDSEAYIGADIKDKLKCYDFDVHTMKTLKNIISPPWDFREFEVEKQTAEETGLTPLETSRKTPDSRPSLEETFEIEMNESDMMLETSMSDHST
Protein: Anaphase-promoting complex subunit CDC26
UniProt accession: Q8NHZ8
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC12, C9orf17, CDC26
Length: 85 residues
Disorder content (fraction disordered): 0.7058823529411765
Curated region start positions: 26
Curated region end positions: 85
Curated region terms: disorder
Domain/feature annotations: Anaphase-promoting complex APC subunit CDC26
Cross-references: PDB:4UI9, PDB:5A31, PDB:5G04, PDB:5G05
Sequence:
MLRRKPTRLELKLDDIEEFENIRKDLETRKKQKEDVEVVGGSDGEGAIGLSSDPKSREQMINDRIGYKPQPKPNNRSSQFGSLEF
Protein: Anaphase-promoting complex subunit 15
UniProt accession: P60006
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC15, C11orf51, HSPC020
Length: 121 residues
Disorder content (fraction disordered): 0.5371900826446281
Curated region start positions: 57
Curated region end positions: 121
Curated region terms: disorder
Domain/feature annotations: Anaphase-promoting complex subunit 15
Cross-references: PDB:4UI9, PDB:5A31, PDB:5G04, PDB:5G05
Sequence:
MSTLFPSLFPRVTETLWFNLDRPCVEETELQQQEQQHQAWLQSIAEKDNNLVPIGKPASEHYDDEEEEDDEDDEDSEEDSEDDEDMQDMDEMNDYNESPDDGEVNEVDMEGNEQDQDQWMI
Protein: Anaphase-promoting complex subunit 16
UniProt accession: Q96DE5
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC16, C10orf104, CENP-27
Length: 110 residues
Disorder content (fraction disordered): 0.4636363636363636
Curated region start positions: 1
Curated region end positions: 51
Curated region terms: disorder
Domain/feature annotations: Anaphase-promoting complex, subunit 16
Cross-references: PDB:4UI9, PDB:5A31, PDB:5G04, PDB:5G05
Sequence:
MAASSSSSSAGGVSGSSVTGSGFSVSDLAPPRKALFTYPKGAGEMLEDGSERFLCESVFSYQVASTLKQVKHDQQVARMEKLAGLVEELEADEWRFKPIEQLLGFTPSSG
Protein: Splicing factor U2AF 35 kDa subunit
UniProt accession: Q01081
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FP793, U2AF1, U2AF35, U2AFBP
Length: 240 residues
Disorder content (fraction disordered): 0.4791666666666667
Dataset labels: Cancer-related proteins
Curated region start positions: 38, 38, 38
Curated region end positions: 152, 152, 152
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: 3.30.70.330, RNA recognition motif, Zinc finger C-x8-C-x5-C-x3-H type (and similar), Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Sequence:
MAEYLASIFGTEKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGLRCAVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHLKPISRELRRELYGRRRKKHRSRSRSRERRSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRERSGRF
Protein: Transportin-1
UniProt accession: Q92973
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KPNB2, MIP1, TNPO1, TRN
Length: 898 residues
Disorder content (fraction disordered): 0.05902004454342984
Curated region start positions: 319
Curated region end positions: 371
Curated region terms: disorder
Domain/feature annotations: Leucine-rich Repeat Variant, Leucine-rich Repeat Variant, Importin-beta N-terminal domain, HEAT-like repeat, Importin subunit beta-1-like, TPR repeats, IPO5-like, TPR repeats
Cross-references: PDB:2Z5M
Sequence:
MVWDRQTKMEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEPEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHDEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPDQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV
Protein: Splicing factor 3B subunit 6
UniProt accession: Q9Y3B4
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CGI-110, HSPC175, HT006, SAP14, SF3B14, SF3B14A, SF3B6
Length: 125 residues
Disorder content (fraction disordered): 0.368
Curated region start positions: 100, 1
Curated region end positions: 125, 20
Curated region terms: disorder, disorder
Domain/feature annotations: 3.30.70.330, RNA recognition motif
Sequence:
MAMQAAKRANIRLPPEVNRILYIRNLPYKITAEEMYDIFGKYGPIRQIRVGNTPETRGTAYVVYEDIFDAKNACDHLSGFNVCNRYLVVLYYNANRAFQKMDTKKKEEQLKLLKEKYGINTDPPK
Protein: Tubulin beta chain
UniProt accession: P41352
Organism: Tetrahymena thermophila
Taxonomy: Eukaryota, Sar, Alveolata, Ciliophora, Intramacronucleata, Oligohymenophorea, Hymenostomatida, Tetrahymenina, Tetrahymenidae, Tetrahymena
Gene names: BTU1, BTU2
Length: 443 residues
Disorder content (fraction disordered): 0.03837471783295711
Curated region start positions: 427
Curated region end positions: 443
Curated region terms: disorder
Domain/feature annotations: Tubulin/FtsZ, C-terminal domain, Helix hairpin bin, Tubulin/FtsZ, GTPase domain, Tubulin/FtsZ family, GTPase domain, Tubulin C-terminal domain
Sequence:
MREIVHIQGGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGRYVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKVREEYPDRIMETFSVVPSPKVSDTVVEPYNATLSVHQLVENADECMVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCAADPRHGRYLTASALFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNIKSSICDIPPKGLKMAVTFVGNSTAIQEMFKRVAEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEEGEN
Protein: Tubulin alpha chain
UniProt accession: P41351
Organism: Tetrahymena thermophila
Taxonomy: Eukaryota, Sar, Alveolata, Ciliophora, Intramacronucleata, Oligohymenophorea, Hymenostomatida, Tetrahymenina, Tetrahymenidae, Tetrahymena
Length: 449 residues
Disorder content (fraction disordered): 0.042316258351893093
Curated region start positions: 431
Curated region end positions: 449
Curated region terms: disorder
Domain/feature annotations: Tubulin/FtsZ, GTPase domain, Tubulin/FtsZ, C-terminal domain, Helix hairpin bin, Tubulin/FtsZ family, GTPase domain, Tubulin C-terminal domain
Sequence:
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPRHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIETAEGEGEEEGY
Protein: Serine/threonine-protein kinase 3
UniProt accession: Q13188
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KRS1, MST2, STK3
Length: 491 residues
Disorder content (fraction disordered): 0.23217922606924643
Dataset labels: Autophagy-related proteins
Curated region start positions: 314, 314, 365, 365, 365, 365, 365
Curated region end positions: 427, 427, 367, 367, 367, 367, 367
Curated region terms: disorder, flexible linker, selective autophagy, selective autophagy, selective autophagy, selective autophagy, protein binding
Domain/feature annotations: Phosphorylase Kinase; domain 1, Transferase(Phosphotransferase) domain 1, Protein kinase domain, C terminal SARAH domain of Mst1
Sequence:
MEQPPAPKSKLKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQEIIKEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAMEIKAKRHEEQQRELEEEEENSDEDELDSHTMVKTSVESVGTMRATSTMSEGAQTMIEHNSTMLESDLGTMVINSEDEEEEDGTMKRNATSPQVQRPSFMDYFDKQDFKNKSHENCNQNMHEPFPMSKNVFPDNWKVPQDGDFDFLKNLSLEELQMRLKALDPMMEREIEELRQRYTAKRQPILDAMDAKKRRQQNF
Protein: AF4/FMR2 family member 4
UniProt accession: Q9UHB7
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AF5Q31, AFF4, HSPC092, MCEF
Length: 1163 residues
Disorder content (fraction disordered): 0.7738607050730868
Dataset labels: Cancer-related proteins, NDDs-related proteins
Curated region start positions: 22, 2, 1, 300, 600, 5, 36
Curated region end positions: 32, 73, 300, 600, 900, 23, 69
Curated region terms: disorder, protein binding, disorder, disorder, disorder, disorder to order, disorder to order
Domain/feature annotations: AF-4 proto-oncoprotein N-terminal region, AF4 interaction motif, AFF4, C-terminal homology domain
Cross-references: PDB:4IMY
Sequence:
MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS
Protein: Gap junction gamma-1 protein
UniProt accession: P28229
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Cxn-45, Gja7, Gjc1
Length: 396 residues
Disorder content (fraction disordered): 0.2601010101010101
Curated region start positions: 265, 265, 265, 362, 362
Curated region end positions: 332, 332, 332, 396, 396
Curated region terms: disorder, disorder, protein binding, disorder, disorder
Domain/feature annotations: Gap junction channel protein cysteine-rich domain, Connexin
Sequence:
MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALEETEEDHEEDPMMYPEMELESEKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIWEMLHLGFGTIRDSLNSKRRELDDPGAYNYPFTWNTPSAPPGYNIAVKPDQIQYTELSNAKIAYKQNKANIAQEQQYGSHEEHLPADLETLQREIRMAQERLDLAIQAYHHQNNPHGPREKKAKVGSKSGSNKSSISSKSGDGKTSVWI
Protein: Aprataxin and PNK-like factor
UniProt accession: Q8IW19
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: APLF, C2orf13, PALF, XIP1
Length: 511 residues
Disorder content (fraction disordered): 0.1643835616438356
Curated region start positions: 399, 399, 450, 450, 450
Curated region end positions: 420, 420, 511, 511, 511
Curated region terms: disorder, flexible linker, disorder, protein folding chaperone, protein binding
Domain/feature annotations: 2.60.200.20, PBZ domain, PBZ domain, FHA domain
Sequence:
MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLDEDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPILAERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMKRK
Protein: Pre-mRNA-splicing factor NTR2
UniProt accession: P36118
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: NTR2, YKR022C
Length: 322 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 322, 322, 322, 322
Curated region terms: disorder, protein binding, disorder, disorder
Domain/feature annotations: Nineteen complex-related protein 2
Sequence:
MAIKKRNKIRLPSGSPEEVGIDGSAHKPMQQIKPLVSNDSEDDDNDICVLQPIKFKKVPKRDITFDGEQAIKEDNSHYEDLYHSKKNTNASTRNKDDLLILNMEDLMEGNHHLLSDSSEAGSSSEGEHISSIPTRGEIAKLKAQKSLSRRKISESDVTTERDYVKLLDSEDKREIMETIRLNGGLKRNNEKEITNFSDDEMQGFQDEMLALTDNQIAIQKDSKRKIIEKAINEVPYRTNEEWETQLLSKGNINKSNEKIITPLPVLFPDDDESGNSIERINEMVSKICLQRKKVEMRLQALEKTKIDLEKSKASLINKLIGN
Protein: Translocated actin-recruiting phosphoprotein
UniProt accession: Q6GX35
Organism: Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Taxonomy: Bacteria, Chlamydiae, Chlamydiales, Chlamydiaceae, Chlamydia/Chlamydophila group, Chlamydia
Gene names: CTL0716, tarP
Length: 1005 residues
Disorder content (fraction disordered): 0.09950248756218906
Dataset labels: Neglected tropical diseases proteins, Bacterial virulence-related proteins
Curated region start positions: 726, 726, 726, 726
Curated region end positions: 825, 825, 825, 825
Curated region terms: disorder, protein binding, disorder to order, disorder
Domain/feature annotations: Domain of Unknown Function (DUF1547), Domain of Unknown Function (DUF1547)
Cross-references: BMRB:27263
Sequence:
MTNSISGDQPTVTTFTSSTTSASGASGSLGASSVSTTANATVTQTANATNSAATSSIQTTGETVVNYTNSASAPTVTVSTSSSSTQATATSNKTSQAVAGKITSPDTSESSETSSTSSSDHIPSDYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDDSSTSGPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAAALNSLRGSSYSNYDDAAADYEPISTTENIYESIDDSSTSDPENTSGGAAALNSLRGSSYSNYDDAAADYEPISTTENIYENIYESIDGSSTSDPENTSGGAAAALNSLRGSSYTTGPRNEGVFGPGPEGLPDMSLPSYDPTNKTSLLTFLSNPHVKSKMLENSGHFVFIDTDRSSFILVPNGNWDQVCSIKVQNGKTKEDLDIKDLENMCAKFCTGFNKFSGDWDSRVEPMMSAKAGVASGGNLPNTVIINNKFKTCVAYGPWNSREASSGYTPSAWRRGHQVNFGEIFEKANDFNKINWGTQAGPSSEDDGISFSNETPGAGPAAAPSPTPSSIPVINVNVNVGGTNVNIRDTNVNTTNTTPTTQSTDASTDTSDIDNINTNNQTDDINTTDKDSDGAGGVNGDISETESSSGDDSGSVSSSESDKNASVGNDGPAMKDILSAVRKHLDVVYPGDNGGSTEGPLQANQTLGDIVQDMETTGTSQETVVSPWKGSTSSTGSAGGSGSVQTLLPSPPPTPSTTTLRTGTGATTTSLMMGGPIKADIITTGGGGRIPGGGTLEKLLPRIRAHLDISFDGQGDLVSTEEPQLGSIVNKFRKETGSGGIVASVESAPGKPGSAQVLTGTGGDKGNLFQAAAAVTQALGNVAGKVNLAIQGQKLSSLVNDDGKGSVGRDLFQAATQTTQALSSLIDTVG
Protein: P antigen family member 5
UniProt accession: Q96GU1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GAGEE1, PAGE5
Length: 130 residues
Disorder content (fraction disordered): 0.8538461538461538
Curated region start positions: 20
Curated region end positions: 130
Curated region terms: disorder
Domain/feature annotations: GAGE protein
Sequence:
MQAPWAGNRGWAGTREEVRDMSEHVTRSQSSERGNDQESSQPVGPVIVQQPTEEKRQEEEPPTDNQGIAPSGEIKNEGAPAVQGTDVEAFQQELALLKIEDAPGDGPDVREGTLPTFDPTKVLEAGEGQL
Protein: Nucleophosmin
UniProt accession: P06748
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NPM, NPM1
Length: 294 residues
Disorder content (fraction disordered): 0.47959183673469385
Dataset labels: Condensates-related proteins, Cancer-related proteins, RNA-binding proteins
Curated region start positions: 189, 120, 119, 120, 120, 120, 189, 197, 217, 233
Curated region end positions: 259, 130, 243, 243, 188, 188, 243, 201, 221, 237
Curated region terms: disorder, disorder, disorder, rRNA binding, protein homodimerization activity, self-inhibition, protein homodimerization activity, phosphorylation display site, phosphorylation display site, phosphorylation display site
Domain/feature annotations: 1.10.10.2100, Nucleoplasmin core domain, Nucleoplasmin/nucleophosmin domain, Nucleophosmin C-terminal domain
Sequence:
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
Protein: Cytotoxicity-associated immunodominant antigen
UniProt accession: P55980
Organism: Helicobacter pylori (strain ATCC 700392 / 26695)
Taxonomy: Bacteria, Proteobacteria, Epsilonproteobacteria, Campylobacterales, Helicobacteraceae, Helicobacter
Gene names: HP_0547, cag26, cagA, cai
Length: 1186 residues
Disorder content (fraction disordered): 0.42495784148397975
Curated region start positions: 877, 893, 893, 893, 893, 1, 222, 479, 510, 824, 222, 510, 877, 877, 998, 998, 877, 877
Curated region end positions: 1186, 1001, 1001, 1001, 1001, 23, 302, 488, 536, 876, 302, 536, 1186, 1186, 1038, 1038, 1186, 1186
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, flexible linker, flexible linker, protein binding, protein binding, protein binding, protein binding, molecular adaptor activity, disorder
Domain/feature annotations: 1.10.357.130, CagA exotoxin domain III, CagA exotoxin domain III, CagA exotoxin phosphopeptide substrate mimic region, CagA exotoxin phosphopeptide substrate mimic region, CagA protein
Cross-references: PDB:4DVY, PDB:4DVZ
Sequence:
MTNETIDQTRTPDQTQSQTAFDPQQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFNKKQSSDVKEAINQEPVPHVQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYAGNGGFGDKHDWNATVGYKDQQGNNVATLINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKVDFMEFLAQNNTKLDNLSEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFNNGDLSYTLKDYGKKADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLEAGFNKVAVFNLPDLNNLAITSFVRRNLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAKAMGDFSRVEQVLADLKNFSKEQLAQQAQKNEDFNTGKNSELYQSVKNSVNKTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFNNNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLSKVGLSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKKNVMNLYVESAKKVPASLSAKLDNYAINSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVSLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDIKSGFTHFLANAFSTGYYCLARENAEHGIKNVNTKGGFQKS
Protein: Desmoglein-1
UniProt accession: Q02413
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CDHF4, DSG1
Length: 1049 residues
Disorder content (fraction disordered): 0.2631077216396568
Curated region start positions: 774, 774, 774, 774
Curated region end positions: 1049, 1049, 1049, 1049
Curated region terms: disorder, disorder, disorder, protein binding
Domain/feature annotations: TCF3-CBD (Catenin binding domain), Cadherins, Cadherins, Cadherins, Cadherins, Cadherin domain, Cadherin domain, Cadherin domain, Cadherin, Y-type LIR-motif
Sequence:
MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQYSK