LiteFold/DisProt huggingface dataset:
Protein: Outer membrane virulence protein YopE
UniProt accession: P08008
Organism: Yersinia pseudotuberculosis serotype I (strain IP32953)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Yersiniaceae, Yersinia
Gene names: pYV0025, yop25, yopE
Length: 219 residues
Disorder content (fraction disordered): 0.45662100456621
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 1, 23, 23, 1, 79
Curated region end positions: 100, 78, 78, 100, 100
Curated region terms: disorder, disorder to order, protein binding, flexible N-terminal tail, flexible linker
Domain/feature annotations: Virulence factor YopE uncharacterised domain, Yersinia virulence determinant (YopE), YopE, N terminal
Cross-references: BMRB:15878, BMRB:7426
Sequence:
MKISSFISTSLPLPTSVSGSSSVGEMSGRSVSQQTSDQYANNLAGRTESPQGSSLASRIIERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQQLNSLDAEMLQKNHDQFATGSGPLRGSITQCQGLMQFCGGELQAEASAILNTPVCGIPFSQWGTIGGAASAYVASGVDLTQAANEIKGLAQQMQKLLSLM
Protein: Stage II sporulation protein SB
UniProt accession: O34800
Organism: Bacillus subtilis (strain 168)
Taxonomy: Bacteria, Firmicutes, Bacilli, Bacillales, Bacillaceae, Bacillus
Gene names: BSU12820, spoIISB
Length: 56 residues
Disorder content (fraction disordered): 1
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 1, 1, 1, 1, 1, 9, 1, 1, 1, 13
Curated region end positions: 56, 56, 56, 56, 56, 52, 56, 56, 56, 53
Curated region terms: disorder, protein binding, disorder to order, protein binding, protein binding, disorder to order, toxin sequestering activity, toxin sequestering activity, toxin sequestering activity, toxin sequestering activity
Domain/feature annotations: Single helix  bin, Antitoxin SpoIISB, type II toxin-antitoxin system
Cross-references: PDB:3O6Q
Sequence:
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
Protein: ExsE
UniProt accession: Q9I322
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: PA1711, exsE
Length: 81 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 81, 81, 81, 81, 81, 81
Curated region terms: disorder, disorder, molecular function regulator, protein binding, disorder to order, disorder
Domain/feature annotations: Type III secretion system ExsE
Sequence:
MKIESISPVQPSQDAGAEAVGHFEGRSVTRAAVRGEDRSSVAGLARWLARNVAGDPRSEQALQRLADGDGTPLEARTVRRR
Protein: Glutamine synthetase inactivating factor IF7
UniProt accession: A0A068MVV3
Organism: Synechocystis sp. (strain PCC 6714)
Taxonomy: Bacteria, Cyanobacteria, Synechococcales, Merismopediaceae, Synechocystis, unclassified Synechocystis
Gene names: D082_16680, gifA
Length: 65 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 65, 65, 65, 65, 65, 65
Curated region terms: disorder, protein binding, disorder, disorder, protein binding, protein binding
Cross-references: BMRB:25921
Sequence:
MSTQQQARALMMRHHQFIKNRQQSLLSRAAAEIGVQAEKDFWTTVQGKPQSSFRETYDRSSASLS
Protein: Beclin-1
UniProt accession: Q14457
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BECN1, GT197
Length: 450 residues
Disorder content (fraction disordered): 0.3466666666666667
Dataset labels: Autophagy-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 105, 98, 105, 105, 105, 105, 105, 105, 105, 141, 104, 104, 104, 105, 105, 1, 105, 105, 105, 105, 96, 76, 50, 105, 96, 97, 97
Curated region end positions: 150, 150, 150, 150, 150, 150, 150, 130, 132, 130, 130, 130, 130, 130, 130, 130, 156, 131, 131, 131, 130, 130, 135, 130, 130, 130, 130, 102, 105, 78, 130, 101, 100, 100
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, protein binding, disorder to order, order, protein binding, disorder, disorder, protein binding, order, disorder to order, disorder, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, regulation of autophagy, protein binding, protein binding, protein binding, disorder, disorder, disorder, protein binding, protein binding, selective autophagy
Domain/feature annotations: Autophagy protein 6/Beclin 1, Apg6 BARA domain, Beclin-1 BH3 domain, Bcl-2-interacting, Apg6 coiled-coil region
Cross-references: BMRB:25384, PDB:2PON, PDB:3DVU, PDB:5EFM, PDB:5VAU, PDB:6HOI, PDB:6HOJ
Sequence:
MEGSKTSNNSTMQVSFVCQRCSQPLKLDTSFKILDRVTIQELTAPLLTTAQAKPGETQEEETNSGEEPFIETPRQDGVSRRFIPPARMMSTESANSFTLIGEASDGGTMENLSRRLKVTGDLFDIMSGQTDVDHPLCEECTDTLLDQLDTQLNVTENECQNYKRCLEILEQMNEDDSEQLQMELKELALEEERLIQELEDVEKNRKIVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMRYAQTQLDKLKKTNVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGETRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQFYNK
Protein: Early E1A protein
UniProt accession: P03255
Organism: Human adenovirus C serotype 5
Taxonomy: Viruses, Varidnaviria, Bamfordvirae, Preplasmiviricota, Tectiliviricetes, Rowavirales, Adenoviridae, Mastadenovirus
Length: 289 residues
Disorder content (fraction disordered): 0.4809688581314879
Dataset labels: Viral proteins
Curated region start positions: 53, 1, 1, 1, 53, 27, 106, 106, 1, 53, 59, 53, 27, 113
Curated region end positions: 91, 91, 91, 139, 91, 91, 139, 139, 91, 91, 82, 91, 91, 117
Curated region terms: disorder to order, disorder, protein binding, disorder, disorder, protein binding, disorder, protein binding, molecular sequestering activity, molecular sequestering activity, disorder to order, protein binding, molecular adaptor activity, protein binding
Domain/feature annotations: Early E1A protein
Cross-references: BMRB:16318, ELM:ELME000145, PDB:2KJE
Sequence:
MRHIICHGGVITEEMAASLLDQLIEEVLADNLPPPSHFEPPTLHELYDLDVTAPEDPNEEAVSQIFPDSVMLAVQEGIDLLTFPPAPGSPEPPHLSRQPEQPEQRALGPVSMPNLVPEVIDLTCHEAGFPPSDDEDEEGEEFVLDYVEHPGHGCRSCHYHRRNTGDPDIMCSLCYMRTCGMFVYSPVSEPEPEPEPEPEPARPTRRPKMAPAILRRPTSPVSRECNSSTDSCDSGPSNTPPEIHPVVPLCPIKPVAVRVGGRRQAVECIEDLLNEPGQPLDLSCKRPRP
Protein: Early E1A protein
UniProt accession: P03259
Organism: Human adenovirus A serotype 12
Taxonomy: Viruses, Varidnaviria, Bamfordvirae, Preplasmiviricota, Tectiliviricetes, Rowavirales, Adenoviridae, Mastadenovirus, Human mastadenovirus A
Length: 266 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins
Curated region start positions: 1, 1, 13, 1
Curated region end positions: 266, 81, 27, 81
Curated region terms: disorder, protein binding, disorder to order, molecular sequestering activity
Domain/feature annotations: Early E1A protein
Sequence:
MRTEMTPLVLSYQEADDILEHLVDNFFNEVPSDDDLYVPSLYELYDLDVESAGEDNNEQAVNEFFPESLILAASEGLFLPEPPVLSPVCEPIGGECMPQLHPEDMDLLCYEMGFPCSDSEDEQDENGMAHVSASAAAAAADREREEFQLDHPELPGHNCKSCEHHRNSTGNTDLMCSLCYLRAYNMFIYSPVSDNEPEPNSTLDGDERPSPPKLGSAVPEGVIKPVPQRVTGRRRCAVESILDLIQEEEREQTVPVDLSVKRPRCN
Protein: Reticulon-4
UniProt accession: Q9JK11
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Nogo, Rtn4
Length: 1163 residues
Disorder content (fraction disordered): 0.177128116938951
Curated region start positions: 544, 544, 544, 31
Curated region end positions: 725, 725, 725, 54
Curated region terms: disorder, protein binding, disorder, disorder
Domain/feature annotations: Reticulon
Sequence:
MEDIDQSSLVSSSTDSPPRPPPAFKYQFVTEPEDEEDEEEEEDEEEDDEDLEELEVLERKPAAGLSAAAVPPAAAAPLLDFSSDSVPPAPRGPLPAAPPAAPERQPSWERSPAAPAPSLPPAAAVLPSKLPEDDEPPARPPPPPPAGASPLAEPAAPPSTPAAPKRRGSGSVDETLFALPAASEPVIPSSAEKIMDLMEQPGNTVSSGQEDFPSVLLETAASLPSLSPLSTVSFKEHGYLGNLSAVSSSEGTIEETLNEASKELPERATNPFVNRDLAEFSELEYSEMGSSFKGSPKGESAILVENTKEEVIVRSKDKEDLVCSAALHSPQESPVGKEDRVVSPEKTMDIFNEMQMSVVAPVREEYADFKPFEQAWEVKDTYEGSRDVLAARANVESKVDRKCLEDSLEQKSLGKDSEGRNEDASFPSTPEPVKDSSRAYITCASFTSATESTTANTFPLLEDHTSENKTDEKKIEERKAQIITEKTSPKTSNPFLVAVQDSEADYVTTDTLSKVTEAAVSNMPEGLTPDLVQEACESELNEATGTKIAYETKVDLVQTSEAIQESLYPTAQLCPSFEEAEATPSPVLPDIVMEAPLNSLLPSAGASVVQPSVSPLEAPPPVSYDSIKLEPENPPPYEEAMNVALKALGTKEGIKEPESFNAAVQETEAPYISIACDLIKETKLSTEPSPDFSNYSEIAKFEKSVPEHAELVEDSSPESEPVDLFSDDSIPEVPQTQEEAVMLMKESLTEVSETVAQHKEERLSASPQELGKPYLESFQPNLHSTKDAASNDIPTLTKKEKISLQMEEFNTAIYSNDDLLSSKEDKIKESETFSDSSPIEIIDEFPTFVSAKDDSPKLAKEYTDLEVSDKSEIANIQSGADSLPCLELPCDLSFKNIYPKDEVHVSDEFSENRSSVSKASISPSNVSALEPQTEMGSIVKSKSLTKEAEKKLPSDTEKEDRSLSAVLSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNSTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSIPVIYERHQVQIDHYLGLANKSVKDAMAKIQAKIPGLKRKAD
Protein: Serine/threonine-protein kinase PknG
UniProt accession: P9WI73
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Taxonomy: Bacteria, Actinobacteria, Corynebacteriales, Mycobacteriaceae, Mycobacterium, Mycobacterium tuberculosis complex
Gene names: MTCY22G10.06c, Rv0410c, pknG
Length: 750 residues
Disorder content (fraction disordered): 0.196
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 1, 61, 1, 1, 21, 30, 61, 75, 75, 75, 21, 21
Curated region end positions: 75, 65, 75, 73, 25, 34, 65, 147, 147, 147, 64, 64
Curated region terms: disorder, phosphorylation display site, flexible N-terminal tail, protein autophosphorylation, phosphorylation display site, phosphorylation display site, phosphorylation display site, order, disorder, order to disorder, modulation by symbiont of host cellular process, antiphagocytosis
Domain/feature annotations: Tetratricopeptide repeat domain, Tetratricopeptide repeat domain, Phosphorylase Kinase; domain 1, Transferase(Phosphotransferase) domain 1, Protein kinase domain, Protein kinase G tetratricopeptide repeat, Protein kinase G rubredoxin domain
Sequence:
MAKASETERSGPGTQPADAQTATSATVRPLSTQAVFRPDFGDEDNFPHPTLGPDTEPQDRMATTSRVRPPVRRLGGGLVEIPRAPDIDPLEALMTNPVVPESKRFCWNCGRPVGRSDSETKGASEGWCPYCGSPYSFLPQLNPGDIVAGQYEVKGCIAHGGLGWIYLALDRNVNGRPVVLKGLVHSGDAEAQAMAMAERQFLAEVVHPSIVQIFNFVEHTDRHGDPVGYIVMEYVGGQSLKRSKGQKLPVAEAIAYLLEILPALSYLHSIGLVYNDLKPENIMLTEEQLKLIDLGAVSRINSFGYLYGTPGFQAPEIVRTGPTVATDIYTVGRTLAALTLDLPTRNGRYVDGLPEDDPVLKTYDSYGRLLRRAIDPDPRQRFTTAEEMSAQLTGVLREVVAQDTGVPRPGLSTIFSPSRSTFGVDLLVAHTDVYLDGQVHAEKLTANEIVTALSVPLVDPTDVAASVLQATVLSQPVQTLDSLRAARHGALDADGVDFSESVELPLMEVRALLDLGDVAKATRKLDDLAERVGWRWRLVWYRAVAELLTGDYDSATKHFTEVLDTFPGELAPKLALAATAELAGNTDEHKFYQTVWSTNDGVISAAFGLARARSAEGDRVGAVRTLDEVPPTSRHFTTARLTSAVTLLSGRSTSEVTEEQIRDAARRVEALPPTEPRVLQIRALVLGGALDWLKDNKASTNHILGFPFTSHGLRLGVEASLRSLARVAPTQRHRYTLVDMANKVRPTSTF
Protein: 2S albumin
UniProt accession: P19594
Organism: Glycine max
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, fabids, Fabales, Fabaceae, Papilionoideae, 50 kb inversion clade, NPAAA clade, indigoferoid/millettioid clade, Phaseoleae, Glycine, Glycine subgen. Soja
Length: 158 residues
Disorder content (fraction disordered): 0.2721518987341772
Curated region start positions: 22, 22
Curated region end positions: 64, 64
Curated region terms: disorder, protein binding
Domain/feature annotations: Plant lipid-transfer and hydrophobic proteins
Sequence:
MTKFTILLISLLFCIAHTCSASKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRGDDDDDDDDDNHILRTMRGRINYIRRNEGKDEDEEEEGHMQKCCTEMSELRSPKCQCKALQKIMENQSEELEEKQKKKMEKELINLATMCRFGPMIQCDLSSDD
Protein: RNA polymerase sigma factor RpoN
UniProt accession: O66858
Organism: Aquifex aeolicus (strain VF5)
Taxonomy: Bacteria, Aquificae, Aquificales, Aquificaceae, Aquifex
Gene names: aq_599, rpoN
Length: 398 residues
Disorder content (fraction disordered): 0.1507537688442211
Curated region start positions: 1, 1, 1
Curated region end positions: 60, 60, 60
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: RNA polymerase sigma-54 factor, core-binding domain, Homeodomain-like, Sigma-54 factor, Activator interacting domain (AID), Sigma-54, DNA binding domain, Sigma-54 factor, core binding domain
Sequence:
MLNQRLEVRQKLNLKLLLKQDLELLTYQTQELEKLIHEEVLVNPLIKGVFKKIPKSFEVKETVPYQIPYTPSELEELQQNIKLELEGKEQELALELLNYLNEKGFLSKSVEEISDVLRCSVEELEKVRQKVLRLEPLGVCSKDVWEFLELQIEEIYPEEEEILKKALRDLKRGKKLKPEIKGKLSRLRLFPLSSSAEKVYTFAKVDAIIEEENGEFFIYLYEDFIDIDLNEEYWELYKKSRNLQKELKEAFERYESIRKVLDIRRRNLRKVLEKIVERQKDFLTGKGSLKPLTLREVSSEIGIHESTLSRIVNSKYVKTPVGTYSLRTFFVRESAEGLTQGELMKLIKEIVENEDKRKPYSDQEIANILKEKGFKVARRTVAKYREMLGIPSSRERRI
Protein: Histone H1.0
UniProt accession: P07305
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: H1-0, H1F0, H1FV
Length: 194 residues
Disorder content (fraction disordered): 0.6134020618556701
Dataset labels: Condensates-related proteins
Curated region start positions: 98, 98, 1, 1, 98, 98, 1, 1, 104, 101
Curated region end positions: 194, 194, 22, 22, 194, 194, 22, 22, 194, 194
Curated region terms: disorder, protein binding, disorder, protein binding, disorder, protein binding, disorder, protein binding, protein binding, nucleosome binding
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, linker histone H1 and H5 family
Cross-references: BMRB:27216
Sequence:
MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
Protein: Histone H2A type 1-B/E
UniProt accession: P04908
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: H2AC4, H2AC8, H2AFA, H2AFM, HIST1H2AB, HIST1H2AE
Length: 130 residues
Disorder content (fraction disordered): 0.4615384615384616
Curated region start positions: 1, 1, 1, 98, 98, 98
Curated region end positions: 27, 27, 27, 130, 130, 130
Curated region terms: disorder, acetylation display site, methylation display site, disorder, acetylation display site, methylation display site
Domain/feature annotations: Histone, subunit A, Core histone H2A/H2B/H3/H4 domain, C-terminus of histone H2A
Cross-references: BMRB:11609
Sequence:
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
Protein: Histone H2B type 1-J
UniProt accession: P06899
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: H2BC11, H2BFR, HIST1H2BJ
Length: 126 residues
Disorder content (fraction disordered): 0.30158730158730157
Dataset labels: NDDs-related proteins
Curated region start positions: 1
Curated region end positions: 38
Curated region terms: disorder
Domain/feature annotations: Histone, subunit A, Core histone H2A/H2B/H3/H4 domain
Cross-references: BMRB:11609
Sequence:
MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Protein: Nuclear protein 2
UniProt accession: A6NF83
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NUPR1L, NUPR2
Length: 97 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 97, 97, 97, 97, 97, 97
Curated region terms: disorder, protein binding, disorder, protein binding, disorder, protein binding
Domain/feature annotations: DNA-binding nuclear phosphoprotein p8
Sequence:
MEAPAERALPRLQALARPPPPISYEEELYDCLDYYYLRDFPACGAGRSKGRTRREQALRTNWPAPGGHERKVAQKLLNGQRKRRQRQLHPKMRTRLT
Protein: Uncharacterized protein Rv2232
UniProt accession: P9WPI9
Organism: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Taxonomy: Bacteria, Actinobacteria, Corynebacteriales, Mycobacteriaceae, Mycobacterium, Mycobacterium tuberculosis complex
Gene names: MTCY427.13/MTCY427.14, Rv2232, ptkA
Length: 291 residues
Disorder content (fraction disordered): 0.27835051546391754
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 1, 1
Curated region end positions: 81, 81
Curated region terms: disorder, self-inhibition
Domain/feature annotations: Putative phosphatase; domain 2, HAD superfamily/HAD-like, Haloacid dehalogenase-like hydrolase
Sequence:
MSSPRERRPASQAPRLSRRPPAHQTSRSSPDTTAPTGSGLSNRFVNDNGIVTDTTASGTNCPPPPRAAARRASSPGESPQLVIFDLDGTLTDSARGIVSSFRHALNHIGAPVPEGDLATHIVGPPMHETLRAMGLGESAEEAIVAYRADYSARGWAMNSLFDGIGPLLADLRTAGVRLAVATSKAEPTARRILRHFGIEQHFEVIAGASTDGSRGSKVDVLAHALAQLRPLPERLVMVGDRSHDVDGAAAHGIDTVVVGWGYGRADFIDKTSTTVVTHAATIDELREALGV
Protein: Protein phosphatase 1 regulatory subunit 12A
UniProt accession: O14974
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MBS, MYPT1, PPP1R12A
Length: 1030 residues
Disorder content (fraction disordered): 0.03883495145631067
Dataset labels: NDDs-related proteins
Curated region start positions: 1
Curated region end positions: 40
Curated region terms: disorder
Domain/feature annotations: Ankyrin repeat-containing domain, Ankyrin repeat-containing domain, Ankyrin repeats (3 copies), Ankyrin repeats (3 copies), cGMP-dependent protein kinase interacting domain
Sequence:
MKMADAKQKRNEQLKRWIGSETDLEPPVVKRQKTKVKFDDGAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNEVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHAKSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQTAFDVADEDILGYLEELQKKQNLLHSEKRDKKSPLIESTANMDNNQSQKTFKNKETLIIEPEKNASRIESLEQEKVDEEEEGKKDESSCSSEEDEEDDSESEAETDKTKPLASVTNANTSSTQAAPVAVTTPTVSSGQATPTSPIKKFPTTATKISPKEEERKDESPATWRLGLRKTGSYGALAEITASKEGQKEKDTAGVTRSASSPRLSSSLDNKEKEKDSKGTRLAYVAPTIPRRLASTSDIEEKENRDSSSLRTSSSYTRRKWEDDLKKNSSVNEGSTYHKSCSFGRRQDDLISSSVPSTTSTPTVTSAAGLQKSLLSSTSTTTKITTGSSSAGTQSSTSNRLWAEDSTEKEKDSVPTAVTIPVAPTVVNAAASTTTLTTTTAGTVSSTTEVRERRRSYLTPVRDEESESQRKARSRQARQSRRSTQGVTLTDLQEAEKTIGRSRSTRTREQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVSTSSSTTPSSSLSTMSSSLYASSQLNRPNSLVGITSAYSRGITKENEREGEKREEEKEGEDKSQPKSIRERRRPREKRRSTGVSFWTQDSDENEQEQQSDTEEGSNKKETQTDSISRYETSSTSAGDRYDSLLGRSGSYSYLEERKPYSSRLEKDDSTDFKKLYEQILAENEKLKAQLHDTNMELTDLKLQLEKATQRQERFADRSLLEMEKRERRALERRISEMEEELKMLPDLKADNQRLKDENGALIRVISKLSK
Protein: Apoptosis-stimulating of p53 protein 2
UniProt accession: Q13625
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ASPP2, BBP, TP53BP2
Length: 1128 residues
Disorder content (fraction disordered): 0.5212765957446809
Curated region start positions: 331, 331, 331, 693, 693, 484, 331, 484, 693, 710, 693, 693, 693, 893, 693, 693
Curated region end positions: 692, 692, 692, 918, 918, 692, 692, 692, 918, 904, 918, 918, 752, 912, 918, 918
Curated region terms: disorder, disorder, disorder, disorder, disorder, protein binding, protein binding, protein binding, protein binding, protein binding, self-assembly, protein homodimerization activity, protein homodimerization activity, protein homodimerization activity, self-inhibition, self-inhibition
Domain/feature annotations: Ankyrin repeat-containing domain, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, SH3 domain, Ankyrin repeats (3 copies), Apoptosis-stimulating of p53 protein 2-like, N-terminal RA domain
Sequence:
MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA
Protein: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
UniProt accession: Q9HAN9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NMNAT, NMNAT1
Length: 279 residues
Disorder content (fraction disordered): 0.13620071684587814
Dataset labels: NDDs-related proteins
Curated region start positions: 109
Curated region end positions: 146
Curated region terms: disorder
Domain/feature annotations: Cytidylyltransferase-like
Cross-references: PDB:1KQN
Sequence:
MENSEKTEVVLLACGSFNPITNMHLRLFELAKDYMNGTGRYTVVKGIISPVGDAYKKKGLIPAYHRVIMAELATKNSKWVEVDTWESLQKEWKETLKVLRHHQEKLEASDCDHQQNSPTLERPGRKRKWTETQDSSQKKSLEPKTKAVPKVKLLCGADLLESFAVPNLWKSEDITQIVANYGLICVTRAGNDAQKFIYESDVLWKHRSNIHVVNEWIANDISSTKIRRALRRGQSIRYLVPDLVQEYIEKHNLYSSESEDRNAGVILAPLQRNTAEAKT
Protein: Inositol phosphate phosphatase SopB
UniProt accession: O30916
Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Salmonella
Gene names: STM1091, sigD, sopB
Length: 561 residues
Disorder content (fraction disordered): 0.2638146167557932
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 1, 29
Curated region end positions: 148, 45
Curated region terms: disorder, disorder
Domain/feature annotations: Cell division control protein 42 homolog, Enterobacterial virulence protein IpgD
Cross-references: PDB:4DID
Sequence:
MQIQSFYHSASLKTQEAFKSLQKTLYNGMQILSGQGKAPAKAPDARPEIIVLREPGATWGNYLQHQKASNHSLHNLYNLQRDLLTVAATVLGKQDPVLTSMANQMELAKVKADRPATKQEEAAAKALKKNLIELIAARTQQQDGLPAKEAHRFAAVAFRDAQVKQLNNQPWQTIKNTLTHNGHHYTNTQLPAAEMKIGAKDIFPSAYEGKGVCSWDTKNIHHANNLWMSTVSVHEDGKDKTLFCGIRHGVLSPYHEKDPLLRHVGAENKAKEVLTAALFSKPELLNKALAGEAVSLKLVSVGLLTASNIFGKEGTMVEDQMRAWQSLTQPGKMIHLKIRNKDGDLQTVKIKPDVAAFNVGVNELALKLGFGLKASDSYNAEALHQLLGNDLRPEARPGGWVGEWLAQYPDNYEVVNTLARQIKDIWKNNQHHKDGGEPYKLAQRLAMLAHEIDAVPAWNCKSGKDRTGMMDSEIKREIISLHQTHMLSAPGSLPDSGGQKIFQKVLLNSGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLITS