LiteFold/DisProt huggingface dataset:
Protein: Tryptophan synthase alpha chain
UniProt accession: P0A877
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1252, b1260, trpA
Length: 268 residues
Disorder content (fraction disordered): 0.07835820895522388
Curated region start positions: 55, 55, 55, 55, 54, 54, 54, 54, 54, 54, 54, 54
Curated region end positions: 65, 65, 65, 65, 65, 65, 65, 65, 74, 74, 74, 74
Curated region terms: disorder, molecular adaptor activity, disorder to order, protein binding, disorder, molecular adaptor activity, disorder to order, protein binding, disorder, molecular adaptor activity, disorder to order, protein binding
Domain/feature annotations: Aldolase class I, Tryptophan synthase alpha chain
Cross-references: PDB:1V7Y:A, PDB:1V7Y:B, PDB:1XCF:A
Sequence:
MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS
Protein: Myristoylated alanine-rich C-kinase substrate
UniProt accession: P26645
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Macs, Marcks
Length: 309 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 309, 309, 309, 309
Curated region terms: disorder, calmodulin binding, calmodulin binding, myristoylation display site
Domain/feature annotations: MARCKS family
Sequence:
MGAQFSKTAAKGEATAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAEPGAKEELQANGSAPAADKEEPASGSAATPAAAEKDEAAAATEPGAGAADKEAAEAEPAEPSSPAAEAEGASASSTSSPKAEDGAAPSPSSETPKKKKKRFSFKKSFKLSGFSFKKSKKESGEGAEAEGATAEGAKDEAAAAAGGEGAAAPGEQAGGAGAEGAAGGEPREAEAAEPEQPEQPEQPAAEEPQAEEQSEAAGEKAEEPAPGATAGDASSAAGPEQEAPAATDEAAASAAPAASPEPQPECSPEAPPAPTAE
Protein: Superoxide dismutase-like protein YojM
UniProt accession: O31851
Organism: Bacillus subtilis (strain 168)
Taxonomy: Bacteria, Firmicutes, Bacilli, Bacillales, Bacillaceae, Bacillus
Gene names: BSU19400, yojM
Length: 196 residues
Disorder content (fraction disordered): 0.1887755102040816
Curated region start positions: 89, 89, 89, 89, 89, 89, 89, 89
Curated region end positions: 125, 125, 125, 125, 125, 125, 125, 125
Curated region terms: disorder, molecular function regulator, disorder to order, ion binding, disorder, molecular function regulator, disorder to order, ion binding
Domain/feature annotations: Superoxide dismutase, copper/zinc binding domain, Copper/zinc superoxide dismutase (SODC)
Cross-references: PDB:1S4I, PDB:1U3N
Sequence:
MHRLLLLMMLTALGVAGCGQKKPPDPPNRVPEKKVVETSAFGHHVQLVNREGKAVGFIEIKESDDEGLDIHISANSLRPGASLGFHIYEKGSCVRPDFESAGGPFNPLNKEHGFNNPMGHHAGDLPNLEVGADGKVDVIMNAPDTSLKKGSKLNILDEDGSAFIIHEQADDYLTNPSGNSGARIVCGALLGNNEKQ
Protein: Myc proto-oncogene protein
UniProt accession: P01106-1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BHLHE39, MYC
Length: 439 residues
Disorder content (fraction disordered): 0.5785876993166287
Dataset labels: Autophagy-related proteins, Cancer-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 89, 89, 1, 1, 402, 363, 353, 367, 129, 51, 55, 55, 56, 60, 51
Curated region end positions: 88, 167, 143, 143, 88, 88, 88, 88, 88, 167, 167, 167, 143, 143, 412, 381, 439, 439, 142, 69, 68, 68, 60, 64, 66
Curated region terms: disorder, molten globule, disorder, protein binding, disorder, protein binding, disorder, protein binding, disorder, molten globule, protein binding, protein binding, protein binding, transcription regulator activator activity, disorder, disorder, disorder, SCF ubiquitin ligase complex binding, SCF ubiquitin ligase complex binding, SCF ubiquitin ligase complex binding, protein binding, protein binding, phosphorylation display site, phosphorylation display site, SCF ubiquitin ligase complex binding
Domain/feature annotations: Helix-loop-helix DNA-binding domain
Cross-references: BMRB:26662, BMRB:26663, ELM:DEG_SCF_FBW7_1, ELM:LIG_SH3_2, PDB:1MV0
Sequence:
MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSLRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSGSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPGKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRREQLKHKLEQLRNSCA
Protein: Hypoxia-inducible factor 1-alpha
UniProt accession: Q16665
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BHLHE78, HIF1A, MOP1, PASD8
Length: 826 residues
Disorder content (fraction disordered): 0.4200968523002422
Dataset labels: Autophagy-related proteins, Cancer-related proteins
Curated region start positions: 530, 530, 530, 403, 403, 776, 403, 791, 815, 776, 776, 776, 530, 403, 403, 403, 530, 530, 776, 795, 560, 556, 561, 571, 571
Curated region end positions: 698, 698, 698, 603, 603, 826, 603, 804, 824, 826, 826, 826, 698, 603, 603, 603, 698, 698, 813, 822, 567, 574, 566, 574, 577
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder to order, disorder to order, protein binding, protein binding, protein binding, disorder, disorder, p53 binding, p53 binding, p53 binding, p53 binding, protein binding, transcription regulator activator activity, ubiquitin protein ligase binding, ubiquitin protein ligase binding, ubiquitin protein ligase binding, ubiquitin protein ligase binding, ubiquitin protein ligase binding
Domain/feature annotations: Helix-loop-helix DNA-binding domain, PAS domain, PAS domain, PAS fold, PAS fold, HIF-1 alpha C terminal transactivation domain, Hypoxia-inducible factor-1, Hypoxia-inducible factor 1-alpha bHLH domain
Cross-references: BMRB:5327, ELM:DEG_ODPH_VHL_1, IntAct:EBI-7354842, PDB:1L8C, PDB:1LM8, PDB:1LQB
Sequence:
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVMRLTISYLRVRKLLDAGDLDIEDDMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYMGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGRTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECVLKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTETDDQQLEEVPLYNDVMLPSPNEKLQNINLAMSPLPTAETPKPLRSSADPALNQEVALKLEPNPESLELSFTMPQIQDQTPSPSDGSTRQSSPEPNSPSEYCFYVDSDMVNEFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPESASPQSTVTVFQQTQIQEPTANATTTTATTDELKTVTKDRMEDIKILIASPSPTHIHKETTSATSSPYRDTQSRTASPNRAGKGVIEQTEKSHPRSPNVLSVALSQRTTVPEEELNPKILALQNAQRKRKMEHDGSLFQAVGIGTLLQQPDDHAATTSLSWKRVKGCKSSEQNGMEQKTIILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
Protein: DE-cadherin
UniProt accession: Q24298
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG3722, E-cadherin, shg
Length: 1507 residues
Disorder content (fraction disordered): 0.1048440610484406
Curated region start positions: 1350, 1350, 1350, 1350, 1350, 1350, 1350, 1350, 1350
Curated region end positions: 1507, 1507, 1507, 1507, 1507, 1507, 1507, 1507, 1507
Curated region terms: disorder, disorder to order, disorder, disorder to order, protein binding, disorder, protein binding, protein binding, molecular function regulator
Domain/feature annotations: TCF3-CBD (Catenin binding domain), Cadherins, Cadherins, Cadherins, Cadherins, Laminin, Cadherins, 2.60.120.200, Cadherins, Cadherins, Cadherin domain, Cadherin domain, Cadherin domain, Cadherin domain, Cadherin domain, Cadherin, Y-type LIR-motif, Laminin G domain, DE-cadherin, Ig-like domain
Sequence:
MSTSVQRMSRSYHCINMSATPQAGHLNPAQQQTHQQHKRKCRDLGRRLIPARLLLGVIVAISLLSPALALHSPPDKNFSGDNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELADNREYFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGDAFKIGLKTGKITVNQKLDYETITEYELKVRAFDGIYDDYTTVVIKIEDVNDNPPVFKQDYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDNSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLINEMPVYWQENRNPGHVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHANVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEAPETDIGRVFVDDLDDWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVTEDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSLKDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQRLENELDLQMLMVNIDECLIEKFKCEESCTNELHKSSVPYMIYSNTTSFVGVNAFVQAQCVCEAPLMRRCLNGGSPRYGENDVCDCIDGFTGPHCELVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALELDNGYPVLTVDYGSGAIRIRHQHIKMVADRTYQLDIILQRTSIEMTVDNCRLSTCQTLGAPIGPNEFLNVNAPLQLGGTPVDLEQLGRQLNWTHVPNQKGFFGCIRNLTINEQTYNLGMPSVFRNIDSGCQQSVAVAFSFGIDRNFIIAIIVCLALLLIILLAVVVQKKQKNGWHEKDIDDIRETIINYEDEGGGERDTDYDLNVLRTQPFYEEKLYKDPHALQGNMRDPNDIPDIADFLGDKKENCDRDVGATTVDDVRHYAYEGDGNSDGSLSSLASCTDDGDLNFDYLSNFGPRFRKLADMYGEEPSDTDSNVDDDQGWRI
Protein: Rhodopsin
UniProt accession: P02699
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: RHO
Length: 348 residues
Disorder content (fraction disordered): 0.11206896551724138
Curated region start positions: 226, 327, 327, 334
Curated region end positions: 242, 348, 348, 348
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: Rhodopsin 7-helix transmembrane proteins, 7 transmembrane receptor (rhodopsin family), Amino terminal of the G-protein receptor rhodopsin
Cross-references: PDB:1F88, PDB:1GZM, PDB:1HZX
Sequence:
MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA
Protein: Guanine nucleotide-binding protein G(t) subunit alpha-1
UniProt accession: P04695
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: GNAT1
Length: 350 residues
Disorder content (fraction disordered): 0
Curated region start positions: 340
Curated region end positions: 350
Curated region terms: disorder to order
Domain/feature annotations: GI Alpha 1, domain 2-like, P-loop containing nucleotide triphosphate hydrolases, G-protein alpha subunit
Sequence:
MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
Protein: Cytochrome c oxidase copper chaperone
UniProt accession: Q12287
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: COX17, L1343, YLL009C
Length: 69 residues
Disorder content (fraction disordered): 0.391304347826087
Curated region start positions: 1
Curated region end positions: 27
Curated region terms: disorder
Domain/feature annotations: CytochromE C oxidase copper chaperone, Cytochrome C oxidase copper chaperone (COX17)
Cross-references: PDB:1U96
Sequence:
MTETDKKQEQENHAECEDKPKPCCVCKPEKEERDTCILFNGQDSEKCKEFIEKYKECMKGYGFEVPSAN
Protein: Gap junction alpha-1 protein
UniProt accession: P08050
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Cxn-43, Gja1
Length: 382 residues
Disorder content (fraction disordered): 0.33507853403141363
Curated region start positions: 255, 264, 327, 327, 364, 255
Curated region end positions: 314, 372, 382, 382, 382, 382
Curated region terms: disorder, SH3 domain binding, disorder, flexible C-terminal tail, protein binding, disorder
Domain/feature annotations: Connexin43, Gap junction channel protein cysteine-rich domain, Connexin, Gap junction alpha-1 protein (Cx43)
Cross-references: PDB:1R5S
Sequence:
MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVNVEMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSVFEVAFLLIQWYIYGFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKGRSDPYHATTGPLSPSKDCGSPKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNYNKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNAKKVAAGHELQPLAIVDQRPSSRASSRASSRPRPDDLEI
Protein: Olfactory marker protein
UniProt accession: P08523
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Omp
Length: 163 residues
Disorder content (fraction disordered): 0
Curated region start positions: 35, 35, 57, 57, 84, 84
Curated region end positions: 49, 49, 68, 68, 99, 99
Curated region terms: disorder to order, protein binding, disorder to order, protein binding, disorder to order, protein binding
Domain/feature annotations: Olfactory marker, Olfactory marker protein
Sequence:
MAEDGPQKQQLDMPLVLDQDLTKQMRLRVESLKQRGEKKQDGEKLLRPAESVYRLDFIQQQKLQFDHWNVVLDKPGKVTITGTSQNWTPDLTNLMTRQLLDPAAIFWRKEDSDAMDWNEADALEFGERLSDLAKIRKVMYFLITFGEGVEPANLKASVVFNQL
Protein: Copper-transporting ATPase 1
UniProt accession: Q04656
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ATP7A, MC1, MNK
Length: 1500 residues
Disorder content (fraction disordered): 0.034666666666666665
Dataset labels: NDDs-related proteins, Age-related disorders proteins
Curated region start positions: 1125
Curated region end positions: 1176
Curated region terms: disorder
Domain/feature annotations: Calcium-transporting ATPase, cytoplasmic domain N, 3.30.70.100, 3.30.70.100, 3.30.70.100, 3.30.70.100, 3.30.70.100, 3.30.70.100, P-type ATPase actuator domain, Heavy-metal-associated domain, Heavy-metal-associated domain, Heavy-metal-associated domain, Heavy-metal-associated domain, Heavy-metal-associated domain, Heavy-metal-associated domain, haloacid dehalogenase-like hydrolase
Cross-references: BMRB:16440, BMRB:16441, PDB:2KMV, PDB:2KMX
Sequence:
MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRKTVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTAL
Protein: Baseplate central spike complex protein gp5
UniProt accession: P16009
Organism: Enterobacteria phage T4
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Uroviricota, Caudoviricetes, Caudovirales, Myoviridae, Tevenvirinae, Tequatrovirus
Gene names: 5
Length: 575 residues
Disorder content (fraction disordered): 0.02782608695652174
Dataset labels: Viral proteins
Curated region start positions: 346, 346, 346, 346, 350, 346
Curated region end positions: 361, 361, 361, 361, 354, 361
Curated region terms: disorder, disorder, disorder, flexible linker, limited proteolysis display site, limited proteolysis display site
Domain/feature annotations: 1.10.530.40, 3.10.450.190, Nucleic acid-binding protein domain, 3.10.450.190, Phage lysozyme, Gp5 N-terminal OB domain, Gp5 C-terminal repeat (3 copies), Gp5 C-terminal repeat (3 copies), Gp5 C-terminal repeat (3 copies)
Cross-references: PDB:1K28, PDB:1PDL, PDB:5IV5
Sequence:
MEMISNNLNWFVGVVEDRMDPLKLGRVRVRVVGLHPPQRAQGDVMGIPTEKLPWMSVIQPITSAAMSGIGGSVTGPVEGTRVYGHFLDKWKTNGIVLGTYGGIVREKPNRLEGFSDPTGQYPRRLGNDTNVLNQGGEVGYDSSSNVIQDSNLDTAINPDDRPLSEIPTDDNPNMSMAEMLRRDEGLRLKVYWDTEGYPTIGIGHLIMKQPVRDMAQINKVLSKQVGREITGNPGSITMEEATTLFERDLADMQRDIKSHSKVGPVWQAVNRSRQMALENMAFQMGVGGVAKFNTMLTAMLAGDWEKAYKAGRDSLWYQQTKGRASRVTMIILTGNLESYGVEVKTPARSLSAMAATVAKSSDPADPPIPNDSRILFKEPVSSYKGEYPYVHTMETESGHIQEFDDTPGQERYRLVHPTGTYEEVSPSGRRTRKTVDNLYDITNADGNFLVAGDKKTNVGGSEIYYNMDNRLHQIDGSNTIFVRGDETKTVEGNGTILVKGNVTIIVEGNADITVKGDATTLVEGNQTNTVNGNLSWKVAGTVDWDVGGDWTEKMASMSSISSGQYTIDGSRIDIG
Protein: Glutenin, high molecular weight subunit DX5
UniProt accession: P10388
Organism: Triticum aestivum
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, Liliopsida, Poales, Poaceae, BOP clade, Pooideae, Triticodae, Triticeae, Triticinae, Triticum
Gene names: GLU-1D-1D, GLU-D1-1B
Length: 848 residues
Disorder content (fraction disordered): 0.3466981132075472
Curated region start positions: 168, 168
Curated region end positions: 461, 461
Curated region terms: disorder, pre-molten globule
Domain/feature annotations: High molecular weight glutenin subunit
Sequence:
MAKRLVLFVAVVVALVALTVAEGEASEQLQCERELQELQERELKACQQVMDQQLRDISPECHPVVVSPVAGQYEQQIVVPPKGGSFYPGETTPPQQLQQRIFWGIPALLKRYYPSVTCPQQVSYYPGQASPQRPGQGQQPGQGQQGYYPTSPQQPGQWQQPEQGQPRYYPTSPQQSGQLQQPAQGQQPGQGQQGQQPGQGQPGYYPTSSQLQPGQLQQPAQGQQGQQPGQAQQGQQPGQGQQPGQGQQGQQPGQGQQPGQGQQGQQLGQGQQGYYPTSLQQSGQGQPGYYPTSLQQLGQGQSGYYPTSPQQPGQGQQPGQLQQPAQGQQPGQGQQGQQPGQGQQGQQPGQGQQPGQGQPGYYPTSPQQSGQGQPGYYPTSSQQPTQSQQPGQGQQGQQVGQGQQAQQPGQGQQPGQGQPGYYPTSPQQSGQGQPGYYLTSPQQSGQGQQPGQLQQSAQGQKGQQPGQGQQPGQGQQGQQPGQGQQGQQPGQGQPGYYPTSPQQSGQGQQPGQWQQPGQGQPGYYPTSPLQPGQGQPGYDPTSPQQPGQGQQPGQLQQPAQGQQGQQLAQGQQGQQPAQVQQGQRPAQGQQGQQPGQGQQGQQLGQGQQGQQPGQGQQGQQPAQGQQGQQPGQGQQGQQPGQGQQGQQPGQGQQPGQGQPWYYPTSPQESGQGQQPGQWQQPGQGQPGYYLTSPLQLGQGQQGYYPTSLQQPGQGQQPGQWQQSGQGQHWYYPTSPQLSGQGQRPGQWLQPGQGQQGYYPTSPQQPGQGQQLGQWLQPGQGQQGYYPTSLQQTGQGQQSGQGQQGYYSSYHVSVEHQAASLKVAKAQQLAAQLPAMCRLEGGDALSASQ
Protein: Protein quaking-A
UniProt accession: Q32NN2
Organism: Xenopus laevis
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Amphibia, Batrachia, Anura, Pipoidea, Pipidae, Xenopodinae, Xenopus, Xenopus
Gene names: qki-a
Length: 341 residues
Disorder content (fraction disordered): 0.03812316715542522
Dataset labels: RNA-binding proteins
Curated region start positions: 203
Curated region end positions: 215
Curated region terms: disorder
Domain/feature annotations: K Homology domain, type 1, Homodimerisation region of STAR domain protein, Putative nuclear localisation signal of quaking, KHDC4/BBP-like, KH-domain type I
Cross-references: PDB:2BL5
Sequence:
MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFTHLERLLDEEISRVRKDMYNDTMNSSSNEKRTSELPDGIGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAELKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANLKSPALAFSLAATGQAPRIITGPAPVLSPAALRTPTPAGHTLMPLIRQIQTAVMPNGTPHPTATLMQQAPEGGLIYTPYEYPYTLAPATSILEYPIEASGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN
Protein: Antitoxin phd
UniProt accession: Q06253
Organism: Escherichia phage P1
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Uroviricota, Caudoviricetes, Caudovirales, Myoviridae, Punavirus
Gene names: phd
Length: 73 residues
Disorder content (fraction disordered): 1
Dataset labels: Unicellular toxins and antitoxins, Viral proteins
Curated region start positions: 52, 52, 52, 41, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 56, 1, 1, 1, 1, 1, 1, 1, 51, 51, 58, 51, 41, 1
Curated region end positions: 73, 73, 73, 73, 73, 73, 73, 73, 73, 57, 57, 73, 57, 57, 73, 73, 73, 73, 58, 58, 73, 73, 73, 73, 73, 73, 73, 73, 73, 73, 73, 73, 57, 73
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder, disorder to order, protein binding, DNA-binding transcription repressor activity, DNA-binding transcription repressor activity, disorder, disorder, disorder, disorder to order, protein binding, protein binding, DNA binding, protein binding, DNA binding, protein binding, disorder to order, protein binding, disorder to order, protein binding, protein binding, DNA binding, protein binding, disorder to order, toxin sequestering activity, protein binding, disorder to order, disorder, order, order to disorder, negative regulation of transcription, DNA-templated
Domain/feature annotations: YefM-like domain, Antitoxin Phd_YefM, type II toxin-antitoxin system
Cross-references: PDB:3DD7, PDB:3HRY, PDB:3HS2, PDB:3K33, PDB:3dd7
Sequence:
MQSINFRTARGNLSEVLNNVEAGEEVEITRRGREPAVIVSKATFEAYKKAALDAEFASLFDTLDSTNKELVNR
Protein: Calsenilin
UniProt accession: Q9QXT8
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Csen, Dream, Kchip3, Kcnip3
Length: 256 residues
Disorder content (fraction disordered): 0.75
Curated region start positions: 65, 198, 65, 65, 139, 175, 223, 65, 65, 65, 65, 223, 175
Curated region end positions: 77, 211, 256, 256, 150, 186, 234, 256, 256, 256, 256, 234, 186
Curated region terms: disorder, disorder, molten globule to order, calcium ion binding, calcium ion binding, calcium ion binding, calcium ion binding, magnesium ion binding, protein homodimerization activity, molten globule, transcription cis-regulatory region binding, negative regulation of DNA binding, negative regulation of DNA binding
Domain/feature annotations: EF-hand, EF-hand domain pair, EF-hand domain pair
Cross-references: PDB:2JUL
Sequence:
MQRTKEAVKASDGNLLGDPGRIPLSKRESIKWQRPRFTRQALMRCCLIKWILSSAAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQKDENIMNSMQLFENVI
Protein: Phosphorelay protein LuxU
UniProt accession: P0C5S4
Organism: Vibrio harveyi
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Vibrionales, Vibrionaceae, Vibrio
Gene names: luxU
Length: 114 residues
Disorder content (fraction disordered): 0.11403508771929824
Curated region start positions: 85
Curated region end positions: 97
Curated region terms: disorder
Domain/feature annotations: HPT domain, Hpt domain
Cross-references: PDB:1Y6D
Sequence:
MNTDVLNQQKIEELSAEIGSDNVPVLLDIFLGEMDSYIGTLTELQGSEQLLYLKEISHALKSSAASFGADRLCERAIAIDKKAKANQLQEQGMETSEMLALLHITRDAYRSWTN