LiteFold/DisProt huggingface dataset:
Protein: DNA repair protein RAD52 homolog
UniProt accession: P43351
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RAD52
Length: 418 residues
Disorder content (fraction disordered): 0.05502392344497608
Curated region start positions: 1
Curated region end positions: 23
Curated region terms: disorder
Domain/feature annotations: DNA repair protein Rad52/59/22, Rad52/22 family double-strand break repair protein
Cross-references: PDB:1H2I
Sequence:
MSGTEEAILGGRDSHPAAGGGSVLCFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDVGYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRSLNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSCRPNMALGHPQLQQVTSPSRPSHAVIPADQDCSSRSLSSSAVESEATHQRKLRQKQLQQQFRERMEKQQVRVSTPSAEKSEAAPPAPPVTHSTPVTVSEPLLEKDFLAGVTQELIKTLEDNSEKWAVTPDAGDGVVKPSSRADPAQTSDTLALNNQMVTQNRTPHSVCHQKPQAKSGSWDLQTYSADQRTTGNWESHRKSQDMKKRKYDPS
Protein: Cysteine and glycine-rich protein 2
UniProt accession: Q05158
Organism: Coturnix japonica
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Archelosauria, Archosauria, Dinosauria, Saurischia, Theropoda, Coelurosauria, Aves, Neognathae, Galloanserae, Galliformes, Phasianidae, Perdicinae, Coturnix
Gene names: CSRP2
Length: 194 residues
Disorder content (fraction disordered): 0.3608247422680412
Curated region start positions: 68, 68, 82, 82, 175, 175
Curated region end positions: 115, 115, 117, 117, 194, 194
Curated region terms: disorder, flexible linker, disorder, flexible linker, disorder, flexible linker
Domain/feature annotations: Cysteine Rich Protein, Cysteine Rich Protein, LIM domain, LIM domain
Cross-references: PDB:1CXX, PDB:1IBI
Sequence:
MPNWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDAEVYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESSPSPHRPTTNPNTSKFAQKFGGAEKCSRCGDSVYAAEKVIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ
Protein: Werner syndrome ATP-dependent helicase
UniProt accession: Q14191
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RECQ3, RECQL2, WRN
Length: 1432 residues
Disorder content (fraction disordered): 0.020251396648044692
Dataset labels: Cancer-related proteins, RNA-binding proteins
Curated region start positions: 1064
Curated region end positions: 1092
Curated region terms: disorder
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Ribonuclease H-like superfamily/Ribonuclease H, P-loop containing nucleotide triphosphate hydrolases, HRDC domain, P-loop containing nucleotide triphosphate hydrolases, DEAD/DEAH box helicase, Helicase conserved C-terminal domain, HRDC domain, 3'-5' exonuclease, RQC domain, Helix-turn-helix domain, RecQ zinc-binding
Cross-references: PDB:2AXL
Sequence:
MSEKKLETTAQQRKCPEWMNVQNKRCAVEERKACVRKSVFEDDLPFLEFTGSIVYSYDASDCSFLSEDISMSLSDGDVVGFDMEWPPLYNRGKLGKVALIQLCVSESKCYLFHVSSMSVFPQGLKMLLENKAVKKAGVGIEGDQWKLLRDFDIKLKNFVELTDVANKKLKCTETWSLNSLVKHLLGKQLLKDKSIRCSNWSKFPLTEDQKLYAATDAYAGFIIYRNLEILDDTVQRFAINKEEEILLSDMNKQLTSISEEVMDLAKHLPHAFSKLENPRRVSILLKDISENLYSLRRMIIGSTNIETELRPSNNLNLLSFEDSTTGGVQQKQIREHEVLIHVEDETWDPTLDHLAKHDGEDVLGNKVERKEDGFEDGVEDNKLKENMERACLMSLDITEHELQILEQQSQEEYLSDIAYKSTEHLSPNDNENDTSYVIESDEDLEMEMLKHLSPNDNENDTSYVIESDEDLEMEMLKSLENLNSGTVEPTHSKCLKMERNLGLPTKEEEEDDENEANEGEEDDDKDFLWPAPNEEQVTCLKMYFGHSSFKPVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGKIGLVISPLISLMEDQVLQLKMSNIPACFLGSAQSENVLTDIKLGKYRIVYVTPEYCSGNMGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVALTATASSSIREDIVRCLNLRNPQITCTGFDRPNLYLEVRRKTGNILQDLQPFLVKTSSHWEFEGPTIIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEIQCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPADINLNRHLLTEIRNEKFRLYKLKMMAKMEKYLHSSRCRRQIILSHFEDKQVQKASLGIMGTEKCCDNCRSRLDHCYSMDDSEDTSWDFGPQAFKLLSAVDILGEKFGIGLPILFLRGSNSQRLADQYRRHSLFGTGKDQTESWWKAFSRQLITEGFLVEVSRYNKFMKICALTKKGRNWLHKANTESQSLILQANEELCPKKLLLPSSKTVSSGTKEHCYNQVPVELSTEKKSNLEKLYSYKPCDKISSGSNISKKSIMVQSPEKAYSSSQPVISAQEQETQIVLYGKLVEARQKHANKMDVPPAILATNKILVDMAKMRPTTVENVKRIDGVSEGKAAMLAPLLEVIKHFCQTNSVQTDLFSSTKPQEEQKTSLVAKNKICTLSQSMAITYSLFQEKKMPLKSIAESRILPLMTIGMHLSQAVKAGCPLDLERAGLTPEVQKIIADVIRNPPVNSDMSKISLIRMLVPENIDTYLIHMAIEILKHGPDSGLQPSCDVNKRRCFPGSEEICSSSKRSKEEVGINTETSSAERKRRLPVWFAKGSDTSKKLMDKTKRGGLFS
Protein: Suppressor of cytokine signaling 3
UniProt accession: O35718
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Cis3, Cish3, Socs3
Length: 225 residues
Disorder content (fraction disordered): 0.4
Curated region start positions: 128, 129, 129, 186, 186, 186, 186, 15
Curated region end positions: 163, 163, 163, 225, 197, 197, 197, 28
Curated region terms: disorder, disorder, limited proteolysis display site, disorder, disorder to order, protein binding, protein binding, disorder
Domain/feature annotations: SH2 domain, SH2 domain
Cross-references: BMRB:6580, PDB:2BBU, PDB:2HMH, PDB:2JZ3
Sequence:
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHYMPPPGTPSFSLPPTEPSSEVPEQPPAQALPGSTPKRAYYIYSGGEKIPLVLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
Protein: Phosphoprotein
UniProt accession: P12579
Organism: Human respiratory syncytial virus A (strain Long)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Pneumoviridae, Orthopneumovirus
Gene names: P
Length: 241 residues
Disorder content (fraction disordered): 0.7510373443983402
Dataset labels: Viral proteins
Curated region start positions: 164, 1
Curated region end positions: 241, 103
Curated region terms: disorder, disorder
Domain/feature annotations: Pneumovirus phosphoprotein
Sequence:
MEKFAPEFHGEDANNRATKFLESIKGKFTSPKDPKKKDSIISVNSIDIEVTKESPITSNSTIINPTNETDDNAGNKPNYQRKPLVSFKEDPIPSDNPFSKLYKETIETFDNNEEESSYSYEEINDQTNDNITARLDRIDEKLSEILGMLHTLVVASAGPTSARDGIRDAMVGLREEMIEKIRTEALMTNDRLEAMARLRNEESEKMAKDTSDEVSLNPTSEKLNNLLEGNDSDNDLSLEDF
Protein: FH1/FH2 domain-containing protein 1
UniProt accession: Q9Y613
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FHOD1, FHOS, FHOS1
Length: 1164 residues
Disorder content (fraction disordered): 0.05240549828178694
Curated region start positions: 1104, 1104, 1104, 1104, 1104, 1104
Curated region end positions: 1164, 1164, 1164, 1164, 1164, 1164
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder to order, protein binding
Domain/feature annotations: Formin, FH2 domain, Leucine-rich Repeat Variant, Formin Homology 2 Domain, Formin N-terminal GBD, FHOD1/3 FH3 domain
Sequence:
MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHRLLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPIMPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGPGLEV
Protein: Bcl-2-like protein 1
UniProt accession: P53563
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Bcl2l1, Bclx, Blc2l
Length: 233 residues
Disorder content (fraction disordered): 0.2145922746781116
Curated region start positions: 31
Curated region end positions: 80
Curated region terms: disorder
Domain/feature annotations: Blc2-like, Apoptosis regulator proteins, Bcl-2 family, Bcl-2 homology region 4
Cross-references: PDB:1AF3
Sequence:
MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK
Protein: AP-2 complex subunit mu
UniProt accession: P84092
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Ap2m1
Length: 435 residues
Disorder content (fraction disordered): 0.1057471264367816
Curated region start positions: 130, 130, 130, 223, 135, 135
Curated region end positions: 158, 158, 158, 239, 158, 158
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder, flexible linker
Domain/feature annotations: Mu homology domain, subdomain B, 3.30.450.60, Mu homology domain, subdomain B, Adaptor complexes medium subunit family, Clathrin adaptor complex small chain
Cross-references: PDB:2VGL, PDB:2XA7
Sequence:
MIGGLFIYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNFVLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSKSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGIYETRC
Protein: Mitochondrial fission 1 protein
UniProt accession: Q9Y3D6
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CGI-135, FIS1, TTC11
Length: 152 residues
Disorder content (fraction disordered): 0.16447368421052633
Curated region start positions: 121, 121, 121
Curated region end positions: 145, 145, 145
Curated region terms: disorder, molecular adaptor activity, lipid binding
Domain/feature annotations: Tetratricopeptide repeat domain, Fis1 N-terminal tetratricopeptide repeat, Fis1 C-terminal tetratricopeptide repeat
Cross-references: PDB:1PC2
Sequence:
MEAVLNELVSVEDLLKFEKKFQSEKAAGSVSKSTQFEYAWCLVRSKYNDDIRKGIVLLEELLPKGSKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGLVGMAIVGGMALGVAGLAGLIGLAVSKSKS
Protein: Rab proteins geranylgeranyltransferase component A 1
UniProt accession: P37727
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Chm, Rep1
Length: 650 residues
Disorder content (fraction disordered): 0.21076923076923076
Curated region start positions: 108, 615
Curated region end positions: 208, 650
Curated region terms: disorder, disorder
Domain/feature annotations: FAD/NAD(P)-binding domain, FAD/NAD(P)-binding domain, Guanine Nucleotide Dissociation Inhibitor, domain 2, Guanine Nucleotide Dissociation Inhibitor, domain 1, GDP dissociation inhibitor, RAE1/2 domain I, C-terminal region
Cross-references: PDB:1LTX
Sequence:
MADNLPSDFDVIVIGTGLPESIIAAACSRSGQRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENNDVVTENSMWQEQILENEEAIPLSSKDKTIQHVEVFCYASQDLHKDVEEAGALQKNHASVTSAQSAEAAEAAETSCLPTAVEPLSMGSCEIPAEQSQCPGPESSPEVNDAEATGKKENSDAKSSTEEPSENVPKVQDNTETPKKNRITYSQIIKEGRRFNIDLVSQLLYSRGLLIDLLIKSNVSRYAEFKNITRILAFREGTVEQVPCSRADVFNSKQLTMVEKRMLMKFLTFCVEYEEHPDEYRAYEGTTFSEYLKTQKLTPNLQYFVLHSIAMTSETTSCTVDGLKATKKFLQCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAVIDQFGQRIISKHFIIEDSYLSENTCSRVQYRQISRAVLITDGSVLKTDADQQVSILAVPAEEPGSFGVRVIELCSSTMTCMKGTYLVHLTCMSSKTAREDLERVVQKLFTPYTEIEAENEQVEKPRLLWALYFNMRDSSDISRDCYNDLPSNVYVCSGPDSGLGNDNAVKQAETLFQQICPNEDFCPAPPNPEDIVLDGDSSQQEVPESSVTPETNSETPKESTVLGNPEEPSE
Protein: Colicin-N
UniProt accession: P08083
Organism: Escherichia coli
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: cna
Length: 387 residues
Disorder content (fraction disordered): 0.23255813953488372
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 67, 1, 2, 2, 1, 1, 1, 1, 40, 1, 1, 1, 1, 1, 1, 1, 1, 1, 40, 40, 40, 40, 1
Curated region end positions: 90, 90, 90, 90, 90, 90, 90, 90, 76, 90, 90, 90, 90, 90, 90, 90, 90, 90, 76, 76, 76, 76, 90
Curated region terms: disorder, disorder to order, disorder, protein binding, disorder, disorder, protein binding, protein binding, pre-molten globule, protein binding, protein binding, protein binding, protein binding, protein binding, pre-molten globule, pre-molten globule, disorder, disorder to order, protein binding, protein binding, pre-molten globule to order, protein binding, protein binding
Domain/feature annotations: Colicin, Colicin, Colicin pore forming domain
Cross-references: BMRB:15506, PDB:1A87
Sequence:
MGSNGADNAHNNAFGGGKNPGIGNTSGAGSNGSASSNRGNSNGWSWSNKPHKNDGFHSDGSYHITFHGDNNSKPKPGGNSGNRGNNGDGASAKVGEITITPDNSKPGRYISSNPEYSLLAKLIDAESIKGTEVYTFHTRKGQYVKVTVPDSNIDKMRVDYVNWKGPKYNNKLVKRFVSQFLLFRKEEKEKNEKEALLKASELVSGMGDKLGEYLGVKYKNVAKEVANDIKNFHGRNIRSYNEAMASLNKVLANPKMKVNKSDKDAIVNAWKQVNAKDMANKIGNLGKAFKVADLAIKVEKIREKSIEGYNTGNWGPLLLEVESWIIGGVVAGVAISLFGAVLSFLPISGLAVTALGVIGIMTISYLSSFIDANRVSNINNIISSVIR
Protein: Ribonucleoside-diphosphate reductase subunit M2
UniProt accession: P11157
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Rrm2
Length: 390 residues
Disorder content (fraction disordered): 0.26153846153846155
Curated region start positions: 353, 353, 353, 1
Curated region end positions: 390, 390, 390, 64
Curated region terms: disorder, disorder to order, protein binding, disorder
Domain/feature annotations: Ribonucleotide Reductase, subunit A, Ribonucleotide reductase, small chain
Cross-references: PDB:1XSM
Sequence:
MLSVRTPLATIADQQQLQLSPLKRLTLADKENTPPTLSSTRVLASKAARRIFQDSAELESKAPTNPSVEDEPLLRENPRRFVVFPIEYHDIWQMYKKAEASFWTAEEVDLSKDIQHWEALKPDERHFISHVLAFFAASDGIVNENLVERFSQEVQVTEARCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREYLFNAIETMPCVKKKADWALRWIGDKEATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFKHLVHKPAEQRVREIITNAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFNKIFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSNSTENSFTLDADF
Protein: Mothers against decapentaplegic homolog 4
UniProt accession: Q13485
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DPC4, MADH4, SMAD4
Length: 552 residues
Disorder content (fraction disordered): 0
Dataset labels: Cancer-related proteins
Curated region start positions: 273, 273, 297, 297
Curated region end positions: 284, 284, 306, 306
Curated region terms: order to disorder, protein binding, order to disorder, protein binding
Domain/feature annotations: 2.60.200.10, SMAD MH1 domain, MH1 domain, MH2 domain
Sequence:
MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFDLKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHPPSNRASTETYSTPALLAPSESNATSTANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQNGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTMPIADPQPLD
Protein: NF-kappa-B inhibitor alpha
UniProt accession: P25963
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: IKBA, MAD3, NFKBI, NFKBIA
Length: 317 residues
Disorder content (fraction disordered): 0.34069400630914826
Curated region start positions: 1, 276
Curated region end positions: 66, 317
Curated region terms: disorder, disorder
Domain/feature annotations: Ankyrin repeat-containing domain, Ankyrin repeats (3 copies), Ankyrin repeats (3 copies)
Sequence:
MFQAAERPQEWAMEGPRDGLKKERLLDDRHDSGLDSMKDEEYEQMVKELQEIRLEPQEVPRGSEPWKQQLTEDGDSFLHLAIIHEEKALTMEVIRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEFTEDELPYDDCVFGGQRLTL
Protein: Transcription factor HY5
UniProt accession: O24646
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At5g11260, BZIP56, F2I11_150, HY5
Length: 168 residues
Disorder content (fraction disordered): 0.4583333333333333
Curated region start positions: 1
Curated region end positions: 77
Curated region terms: disorder
Domain/feature annotations: Single helix bin, bZIP transcription factor
Sequence:
MQEQATSSLAASSLPSSSERSSSSAPHLEIKEGIESDEEIRRVPEFGGEAVGKETSGRESGSATGQERTQATVGESQRKRGRTPAEKENKRLKRLLRNRVSAQQARERKKAYLSELENRVKDLENKNSELEERLSTLQNENQMLRHILKNTTGNKRGGGGGSNADASL
Protein: Peroxisomal targeting signal 1 receptor
UniProt accession: P50542
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PEX5, PXR1
Length: 639 residues
Disorder content (fraction disordered): 0.5070422535211268
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 57, 59, 61, 1, 62, 62, 62, 1, 1, 1
Curated region end positions: 324, 324, 324, 324, 110, 71, 70, 67, 110, 66, 66, 66, 100, 197, 268
Curated region terms: disorder, disorder, disorder, disorder, disorder, protein binding, disorder to order, protein binding, protein binding, protein binding, protein binding, protein import into peroxisome matrix, disorder, disorder, disorder
Domain/feature annotations: Tetratricopeptide repeat domain, Tetratricopeptide repeat, Tetratricopeptide repeat, Tetratricopeptide repeat
Cross-references: ELM:LIG_Pex14_3, PDB:4BXU
Sequence:
MAMRELVEAECGGANPLMKLAGHFTQDKALRQEGLRPGPWPPGAPASEAASKPLGVASEDELVAEFLQDQNAPLVSRAPQTFKMDDLLAEMQQIEQSNFRQAPQRAPGVADLALSENWAQEFLAAGDAVDVTQDYNETDWSQEFISEVTDPLSVSPARWAEEYLEQSEEKLWLGEPEGTATDRWYDEYHPEEDLQHTASDFVAKVDDPKLANSEFLKFVRQIGEGQVSLESGAGSGRAQAEQWAAEFIQQQGTSDAWVDQFTRPVNTSALDMEFERAKSAIESDVDFWDKLQAELEEMAKRDAEAHPWLSDYDDLTSATYDKGYQFEEENPLRDHPQPFEEGLRRLQEGDLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTNESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKELFLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRGEGGAMSENIWSTLRLALSMLGQSDAYGAADARDLSTLLTMFGLPQ
Protein: Cryptochrome-2
UniProt accession: Q49AN0
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CRY2, KIAA0658
Length: 593 residues
Disorder content (fraction disordered): 0.17537942664418213
Curated region start positions: 490, 490, 490, 490, 490, 490, 490, 490, 490
Curated region end positions: 593, 593, 593, 593, 593, 593, 593, 593, 593
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder to order, protein binding, disorder, disorder to order, protein binding
Domain/feature annotations: HUPs, DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3, DNA photolyase, FAD binding domain of DNA photolyase
Sequence:
MAATVATAAAVAPAPAPGTDSASSVHWFRKGLRLHDNPALLAAVRGARCVRCVYILDPWFAASSSVGINRWRFLLQSLEDLDTSLRKLNSRLFVVRGQPADVFPRLFKEWGVTRLTFEYDSEPFGKERDAAIMKMAKEAGVEVVTENSHTLYDLDRIIELNGQKPPLTYKRFQAIISRMELPKKPVGLVTSQQMESCRAEIQENHDETYGVPSLEELGFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNANSLLASPTGLSPYLRFGCLSCRLFYYRLWDLYKKVKRNSTPPLSLFGQLLWREFFYTAATNNPRFDRMEGNPICIQIPWDRNPEALAKWAEGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWVSWESGVRVFDELLLDADFSVNAGSWMWLSCSAFFQQFFHCYCPVGFGRRTDPSGDYIRRYLPKLKAFPSRYIYEPWNAPESIQKAAKCIIGVDYPRPIVNHAETSRLNIERMKQIYQQLSRYRGLCLLASVPSCVEDLSHPVAEPSSSQAGSMSSAGPRPLPSGPASPKRKLEAAEEPPGEELSKRARVAELPTPELPSKDA
Protein: Cryptochrome-1
UniProt accession: Q43125
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At4g08920, BLU1, CRY1, HY4, T3H13.14, T3H13.5
Length: 681 residues
Disorder content (fraction disordered): 0.2878120411160059
Curated region start positions: 506, 506, 506, 506, 506, 506, 1, 498
Curated region end positions: 681, 681, 681, 681, 681, 681, 12, 509
Curated region terms: disorder, disorder to order, disorder, disorder to order, disorder, disorder to order, disorder, disorder
Domain/feature annotations: HUPs, 1.25.40.80, DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3, DNA photolyase, FAD binding domain of DNA photolyase, Blue/Ultraviolet sensing protein C terminal
Cross-references: PDB:1U3C
Sequence:
MSGSVSGCGSGGCSIVWFRRDLRVEDNPALAAAVRAGPVIALFVWAPEEEGHYHPGRVSRWWLKNSLAQLDSSLRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFNHLYDPLSLVRDHRAKDVLTAQGIAVRSFNADLLYEPWEVTDELGRPFSMFAAFWERCLSMPYDPESPLLPPKKIISGDVSKCVADPLVFEDDSEKGSNALLARAWSPGWSNGDKALTTFINGPLLEYSKNRRKADSATTSFLSPHLHFGEVSVRKVFHLVRIKQVAWANEGNEAGEESVNLFLKSIGLREYSRYISFNHPYSHERPLLGHLKFFPWAVDENYFKAWRQGRTGYPLVDAGMRELWATGWLHDRIRVVVSSFFVKVLQLPWRWGMKYFWDTLLDADLESDALGWQYITGTLPDSREFDRIDNPQFEGYKFDPNGEYVRRWLPELSRLPTDWIHHPWNAPESVLQAAGIELGSNYPLPIVGLDEAKARLHEALSQMWQLEAASRAAIENGSEEGLGDSAEVEEAPIEFPRDITMEETEPTRLNPNRRYEDQMVPSITSSLIRPEEDEESSLNLRNSVGDSRAEVPRNMVNTNQAQQRRAEPASNQVTAMIPEFNIRIVAESTEDSTAESSSSGRRERSGGIVPEWSPGYSEQFPSEENGIGGGSTTSSYLQNHHEILNWRRLSQTG
Protein: H/ACA ribonucleoprotein complex subunit NOP10
UniProt accession: Q6Q547
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: NOP10, YHR072W-A
Length: 58 residues
Disorder content (fraction disordered): 0.6724137931034483
Curated region start positions: 49, 17, 42
Curated region end positions: 58, 38, 58
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: H/ACA ribonucleoprotein complex, subunit Nop10, Nucleolar RNA-binding protein, Nop10p family
Cross-references: PDB:3U28
Sequence:
MHLMYTLGPDGKRIYTLKKVTESGEITKSAHPARFSPDDKYSRQRVTLKKRFGLVPGQ
Protein: Sorting nexin-3
UniProt accession: Q08826
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: GRD19, SNX3, YOR357C
Length: 162 residues
Disorder content (fraction disordered): 0.17901234567901234
Curated region start positions: 1
Curated region end positions: 29
Curated region terms: disorder
Domain/feature annotations: Phox-like domain, PX domain
Cross-references: PDB:1OCS
Sequence:
MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSNRFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAEKFVG