LiteFold/DisProt huggingface dataset:
Protein: Bone marrow stromal antigen 2
UniProt accession: Q10589
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BST2
Length: 180 residues
Disorder content (fraction disordered): 0.06111111111111111
Curated region start positions: 79, 79
Curated region end positions: 89, 89
Curated region terms: disorder, flexible linker
Domain/feature annotations: Bone marrow stromal antigen 2
Sequence:
MASTSYDYCRVPMEDGDKRCKLLLGIGILVLLIIVILGVPLIIFTIKANSEACRDGLRAVMECRNVTHLLQQELTEAQKGFQDVEAQAATCNHTVMALMASLDAEKAQGQKKVEELEGEITTLNHKLQDASAEVERLRRENQVLSVRIADKKYYPSSQDSSSAAAPQLLIVLLGLSALLQ
Protein: Protein Nef
UniProt accession: Q5QGG3
Organism: Simian immunodeficiency virus
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 263 residues
Disorder content (fraction disordered): 0.2129277566539924
Dataset labels: Viral proteins
Curated region start positions: 184, 66, 87, 87, 87
Curated region end positions: 202, 102, 106, 106, 106
Curated region terms: disorder, disorder, disorder to order, protein binding, receptor-mediated endocytosis of virus by host cell
Domain/feature annotations: Nef Regulatory Factor, Negative factor, (F-Protein) or Nef
Cross-references: PDB:5NUH, PDB:5NUI
Sequence:
MGGAISMRRSRPSGDLRQRLLRARGETYGRLLGEVEDGYSQSPGGLDKGLSSLSCEGQKYNQGQYMNTPWRNPAEEREKLAYRKQNMDDIDEZDDDLVGVSVRPKVPLRTMSYKLAIDMSHFIKEKGGLEGIYYSARRHRILDIYLEKEEGIIPDWQDYTSGPGIRYPKTFGWLWKLVPVNVSDEAQEDEEHYLMHPAQTSQWDDPWGEVLAWKFDPTLAYTYEAYVRYPEEFGSKSGLSEEEVRRRLTARGLLNMADKKETR
Protein: AP-2 complex subunit beta
UniProt accession: P62944
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Ap2b1, Clapb1
Length: 937 residues
Disorder content (fraction disordered): 0.0128068303094984
Curated region start positions: 7, 7, 7, 7, 7, 7, 7
Curated region end positions: 18, 18, 18, 18, 18, 18, 18
Curated region terms: disorder, disorder to order, protein binding, molecular function regulator, molecular function regulator, molecular function regulator, protein binding
Domain/feature annotations: Leucine-rich Repeat Variant, TATA-Binding Protein, G3DSA:2.60.40.1150, Adaptin N terminal region, Adaptin C-terminal domain, Beta2-adaptin appendage, C-terminal sub-domain
Cross-references: PDB:6OWT
Sequence:
MTDSKYFTTNKKGEIFELKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVYLYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSHANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALRNINLIVQKRPEILKQEIKVFFVKYNDPIYVKLEKLDIMIRLASQANIAQVLAELKEYATEVDVDFVRKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERIDNADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQQVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTAKEVVLSEKPLISEETDLIEPTLLDELICHIGSLASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGDSPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLGPPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIPSSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVFLATWKDIPNENELQFQIKECHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELRIQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN
Protein: Protein Nef
UniProt accession: Q70627
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate LW123)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 206 residues
Disorder content (fraction disordered): 0.21359223300970873
Dataset labels: Viral proteins
Curated region start positions: 60, 149
Curated region end positions: 71, 180
Curated region terms: disorder, disorder
Domain/feature annotations: HIV 1 nef anchor domain, Nef Regulatory Factor, Negative factor, (F-Protein) or Nef
Cross-references: PDB:2NEF
Sequence:
MGGKWSKSSVIGWPTVRERMRRAEPAADGVGAASQDLEKHGAITSSNTAATNADCAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPEKLEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: Ubiquitin carboxyl-terminal hydrolase calypso
UniProt accession: Q7K5N4
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG8445, calypso
Length: 471 residues
Disorder content (fraction disordered): 0.09978768577494691
Curated region start positions: 195, 304
Curated region end positions: 210, 334
Curated region terms: disorder, disorder
Domain/feature annotations: Peptidase C12, ubiquitin carboxyl-terminal hydrolase, Ubiquitin carboxyl-terminal hydrolase, family 1, Ubiquitin carboxyl-terminal hydrolases
Cross-references: PDB:6CGA
Sequence:
MNAAGGGSGAQAAAVAAGNNSLSHNALLSTASGATTMPMAQLADGWLELESDPGLFTLLLKDFGCHDVQVEEVYDLQKPIESPYGFIFLFRWIEERRARRKIVETTAEIFVKDEEAISSIFFAQQVVPNSCATHALLSVLLNCNENNLQLGDTLSRLKTHTKGMSPENKGLAIGNTPELACAHNSHAMPQARRRLERTGAGVSSCRFTGEAFHFVSFVPINGQLFELDGLKPYPMNHGGWEDSEDWTDKFRRVMAERLGIATGEQDIRFNLMAVVPDRRIAITHKLKMLRTNQAIVSGTLQKLLKADEQGESGNGDSQRPDTPTTLLEPSAFTARDLQSLLKNLDTEIAINEQHLADENDRRHMFKVDASRRTHNYDKFICTFLSMLAHQGVLGELVSQHLLPSKKVSGQGAANRISKQSTTASAGGSTAAGTASTPKTQQQQAAAAKNGKSPSKTPGRRRKGRNKCRKRK
Protein: Polycomb protein Asx
UniProt accession: Q9V727
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: Asx, CG8787
Length: 1669 residues
Disorder content (fraction disordered): 0.03055721989215099
Curated region start positions: 310, 254
Curated region end positions: 340, 273
Curated region terms: disorder, disorder
Domain/feature annotations: Asx homology domain, PHD domain of transcriptional enhancer, Asx
Cross-references: PDB:6CGA
Sequence:
MKTITPDTTTTTSSQHQQLLIPQADQHHQPMLQQQSLLAAPPPTMIMEHVNLVDDDEKDPLALEQLEVSPSTKHTHSLRRHLPRIIVKPIPPEKKPMAPSEEAAVSTAPAPPTRLICSRRIQQQQQVKAAAAAAAAAAAAAAAAAAAAQAQATSSYPSAISPGSKAGTSQASTMREVLASIPGFSVKPRRRSNKKLTTAAQIEQTKDGKIDLETPDSILASTNLRALLNKQTFSLLPPLYQYNLIQLLPSVDREASELEQPSSSASGGSPSEAIRLSASCLNNEFFARACLEWRERLSEGEFTPENQLKLKTEAEREKNKLDPWKLKHFEPFWGEKNSRGKDKDKLESDCKNQKLSASIKSEPKPPATSQQKPLQQATCDNETELKFDLSTKCETTSAKTTVAVAVADKSSTFPPTGSQNNVLNEQQRRVLKRPSSSPSQRKQAPTTIATINLDDDLDELPSTSKDSKQPKMDEIVPNASGNVVAAPMVDVVDHSAVEMKIKDEQQHQRQHQPLINSTCDKIEPSECSKEMIVAMKQVDSKEDVDSIASAAAMPAIAAVTPHTPKPEALAPNPDVANQFVSYLQNVELAAETKAPLDNSNEADITTGTNSHDFVFSDTIDHAYFQEHQSTINHNFFTSSSSSNTATTAANKLEEHSDKPEDSPLPIASSISGSTPASSITSTSCTSSSSSSASMSSSCSSSNSGSTTTAPTTSSSAGAPTAPLTLAAAAETTLANVQAMLSTVAKLQQQQQELPVELNSNEMYQHVQHDWNFGDIKLSSSQSSGDQQRNLSHEAIDLMDVVQDADVIDDIMHNDVCHDVLGDEDEGDQEEDEDDEVVECMTEEQQLIDEDSEAVREIVDKLQQHQQQQNQQQHHQQLHIQDVVQLAQHSFMPQAHSEFGNDIGQEMLCDAVPMSAAEMEVSSTVITNSSNSNDSSNNISLCSSTNSLTINQMPHQASQQPQQNAQSNAQQQRQILVDSNGQIIGNFLLQQQRQQQQQQLLQQFTLQAAAAQQQQQQQQQHQQQQQQQQQATSSNSLGKTLPVALRNGTQQFLSPNLIAQQHQQQQQQQLEQHQQQATAQQKHQQIQQFALQQAQLHQRQLLAQAANNNLLQQQQQQQQNVALPTTQAKFIAKPLNIISMTRPANASPTTAATTANTASIPSAYANVVAVTGAQQQQSPPVPAPQQQTVQQQQLANHNSNMQQLPNVLTMKTLPPSGVPTTIAQQRLQPKMPTGKGRKATSNRLPPGAVNLERSYQICQAVIQNSPNRENLKAQLRPPAAILNQHQPTTTTAPAPINPVTLNVSTVAATPMSNITTATGSMAAAVAAAPPQNVLKQEELLVSGAVGAGALPAGLPPNVMGVGRPGVYKVIGPRMSGFPRKKYVQRKPSPTTLIRHVFSPGPGGATATAQQLQMLQQHHQSTTSPVPVQNPQQPAPEQLIHQNGNGQYVLVHRANVGAADNQAPRASSAPPMHQNQFVTVQNPLHSINGIPMGGRGRPASVDTTAGSGNVIAPPISATDALHHHHHEMQQQQQHQQPQPLGNVGAAANIVRRNIAAGPNIAYIDGSNTNSSAVALMEAGNNYIVTTNASPTAAPSPINQQPQSQPTGTQHQHPLLQLHQTGENTPPGNEATATANNCACSLNAMVICQQCGAFCHDDCIGAAKLCVACVIR
Protein: Src kinase-associated phosphoprotein 2
UniProt accession: Q3UND0
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Prap, Ra70, Saps, Scap2, Skap2, Skap55r
Length: 358 residues
Disorder content (fraction disordered): 0.11452513966480447
Curated region start positions: 65, 65
Curated region end positions: 105, 105
Curated region terms: disorder, flexible linker
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), SH3 domain, PH domain
Cross-references: PDB:2OTX
Sequence:
MPNPSCTSSPGPLPEEIRNLLADVETFVADTLKGENLSKKAKEKRESLIKKIKDVKSVYLQEFQDKGDAEDGDEYDDPFAGPADTISLASERYDKDDDGPSDGNQFPPIAAQDLPFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIDGYDVRMNNTLRKDGKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDLGSDVIPEDDEERGELYDDVDHPAAVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVHHTSGDKSTDYANFYQGLWDCTGALSDELSFKRGDVIYILSKEYNRYGWWVGEMKGAIGLVPKAYLMEMYDI
Protein: Isoform 2 of Apoptosis inhibitor 5
UniProt accession: Q9BZZ5-2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: API5, MIG8
Length: 504 residues
Disorder content (fraction disordered): 0.12698412698412698
Curated region start positions: 322, 455, 455, 455
Curated region end positions: 335, 504, 504, 475
Curated region terms: disorder, disorder, disorder, localization
Cross-references: PDB:3U0R
Sequence:
MPTVEELYRNYGILADATEQVGQHKDAYQVILDGVKGGTKEKRLAAQFIPKFFKHFPELADSAINAQLDLCEDEDVSIRRQAIKELPQFATGENLPRVADILTQLLQTDDSAEFNLVNNALLSIFKMDAKGTLGGLFSQILQGEDIVRERAIKFLSTKLKTLPDEVLTKEVEELILTESKKVLEDVTGEEFVLFMKILSGLKSLQTVSGRQQLVELVAEQADLEQTFNPSDPDCVDRLLQCTRQAVPLFSKNVHSTRFVTYFCEQVLPNLGTLTTPVEGLDIQLEVLKLLAEMSSFCGDMEKLETNLRKLFDKLLEYMPLPPEEAENGENAGNEEPKLQFSYVECLLYSFHQLGRKLPDFLTAKLNAEKLKDFKIRLQYFARGLQVYIRQLRLALQGKTGEALKTEENKIKVVALKITNNINVLIKDLFHIPPSYKSTVTLSWKPVQKVEIGQKRASEDTTSGSPPKKSSAGPKRDARQIYNPPSGKYSSNLGNFNYERSLQGK
Protein: RecQ-mediated genome instability protein 2
UniProt accession: Q96E14
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: C16orf75, RMI2
Length: 147 residues
Disorder content (fraction disordered): 0.10884353741496598
Dataset labels: Cancer-related proteins
Curated region start positions: 1
Curated region end positions: 16
Curated region terms: disorder
Domain/feature annotations: RecQ-mediated genome instability protein 2
Cross-references: PDB:3MXN
Sequence:
MAAAADSFSGGPAGVRLPRSPPLKVLAEQLRRDAEGGPGAWRLSRAAAGRGPLDLAAVWMQGRVVMADRGEARLRDPSGDFSVRGLERVPRGRPCLVPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPIHESMWELEVEDLHRNIP
Protein: FERM, ARHGEF and pleckstrin domain-containing protein 2
UniProt accession: Q91VS8
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Farp2, Kiaa0793
Length: 1065 residues
Disorder content (fraction disordered): 0.03568075117370892
Curated region start positions: 869, 869
Curated region end positions: 906, 906
Curated region terms: disorder, flexible linker
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), G3DSA:1.20.80.10, Dbl homology (DH) domain, PH domain, PH domain, FERM central domain, RhoGEF domain, FERM adjacent (FA), FERM N-terminal domain, FERM C-terminal PH-like domain
Cross-references: PDB:4GZU
Sequence:
MGEIEGTYRALPTSGTRLGGQTAIGVSTLEPEQSLSPRMQEKHMRIRVKLLDSTVELFDIEPKCDGQVLLTQVWKHLNLIECDYFGLEFKNVQSYWIWLEPMKPIIRQVRKPKNAVLRLAVKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCTANTAALLISHLLQSEIGDYDETLDREHLKANEYLPNQEKSLEKILDFHQRHTGQTPAESDFQVLEIARKLEMYGIRFHMASDREGTKINLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLLGSRDECKNFWKICVEYHTFFRLSDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYVKDGGMKRIPYERRHSKTRTSLHALTVDLPKQSVSFTDGLRTSASLSSANVSFYPPPSSSLSPPGLPNLKDSSSSLVDPQAPVIKSTAAERSSGPSSSDGPSTQSAHLPGPPVLRPGPGFSMDSPQPSPSSLKSHLSLCPELQAALSTAEQGASPVLSPVLSGAGTARMDNQEEQKHKHMPEDEAYFIAKEILATERTYLKDLEVITVWFRSVLIKEEAMPAALMALLFSNIDPVYEFHRGFLHEVEQRLALWEGPSSAHLKGDHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKHCKKLEAVYKEFELQKVCYLPLNTFLLKPVQRLVHYRLLLSRLCAHYSPGHRDYADCHEALKAITEVTTELQQSLTRLENLQKLTELQRDLVGVENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSDMLLYTSKSVTGASHFRIRGFLPLRGMLVEESENEWSVPHCFTIYAAQKTIVVAASTRLEKEKWMQDLNAAIQAAKTIGDSPPVLLGGPVYTRTPRSSDEVSLEESEDGRGNRGSLEGNSQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSNGWQKLWVVFTNFCLFFYKTHQDDYPLASLPLLGYSVSLPREADSIHKDYVFKLQFKSHVYFFRAESKYTFERWMDVIKRASSSPGRPPSFTQDCSHHSPGLEAEIREKEACPSPCLDKNL
Protein: Protein Nef
UniProt accession: Q90VU7
Organism: Human immunodeficiency virus 1
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 206 residues
Disorder content (fraction disordered): 0.23300970873786409
Dataset labels: Viral proteins
Curated region start positions: 27, 162, 158, 160, 168
Curated region end positions: 56, 174, 168, 165, 179
Curated region terms: disorder, disorder, disorder to order, protein trimerization, disorder
Domain/feature annotations: HIV 1 nef anchor domain, Nef Regulatory Factor, Negative factor, (F-Protein) or Nef
Cross-references: EMDB:EMD-7453, EMDB:EMD-7457, PDB:4EMZ, PDB:4EN2, PDB:6CM9, PDB:6D83
Sequence:
MGGKWSKSSVIGWPAVRERMRRAEPAADGVGAVSRDLEKHGAITSSNTAANNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: AP-1 complex subunit mu-1
UniProt accession: P35585
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Ap1m1, Cltnm
Length: 423 residues
Disorder content (fraction disordered): 0.03073286052009456
Curated region start positions: 219, 218, 218, 218
Curated region end positions: 231, 231, 231, 231
Curated region terms: disorder, disorder to order, protein binding, molecular function regulator
Domain/feature annotations: Adaptor complexes medium subunit family, Clathrin adaptor complex small chain
Cross-references: PDB:1W63, PDB:4EMZ, PDB:4EN2
Sequence:
MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ
Protein: Antitoxin HipB
UniProt accession: P23873
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1501, b1508, hipB
Length: 88 residues
Disorder content (fraction disordered): 0.18181818181818185
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 73, 73
Curated region end positions: 88, 88
Curated region terms: disorder, limited proteolysis display site
Domain/feature annotations: lambda repressor-like DNA-binding domains, Helix-turn-helix
Cross-references: PDB:3DNV, PDB:3HZI
Sequence:
MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQQNLEW
Protein: Cold shock-like protein CspD
UniProt accession: P0A968
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW0864, b0880, cspD, cspH, ybjA
Length: 74 residues
Disorder content (fraction disordered): 1
Dataset labels: Unicellular toxins and antitoxins, RNA-binding proteins
Curated region start positions: 1
Curated region end positions: 74
Curated region terms: disorder
Domain/feature annotations: 'Cold-shock' DNA-binding domain
Sequence:
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
Protein: DUF1778 domain-containing protein
UniProt accession: J7QA90
Organism: Escherichia coli
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: A9X72_01425, AAG43_001902, ACN81_27750, BANRA_04607, BF481_000881, BHS81_20640, BK292_07330, BMT50_11545, BN17_33961, BOH76_21075, BON67_16110, BON68_09795, BON69_15975, BON70_07290, BON71_12410, BON72_01915, BON76_01280, BON94_28105, BvCmsHHP019_01674, C9160_12820, C9E67_02045, CCS08_20675, CR538_01655, DAH19_17150, DAH20_09975, DAH23_09180, DAH24_08965, DAH25_09555, DAH26_09190, DAH29_13330, DAH30_05715, DAH31_09755, DAH42_06460, DAH43_06950, DAH45_07300, DAH46_06945, DAH47_06190, DAH48_06575, DAH49_06925, DEN87_09685, DEN88_06875, DEN89_12920, DEN90_11110, DEN91_13510, DEN92_11790, DEN95_20050, DEO04_12010, DEO05_11020, DEO06_11255, DEO07_11670, DEO08_08190, DEO09_11685, DEO10_12650, DEO11_11680, DEO18_07855, DEO20_22645, DS732_25100, E0I42_12085, E2113_17730, E2117_15630, E5M02_05865, E5P24_11930, E5P25_18400, E5P33_10590, E5P39_05805, E5P41_10150, E5P42_15500, E5P43_02700, E5P44_18685, E5P45_04330, E5P46_15485, E5P47_14950, E5P48_01580, E5P49_04010, E5P50_07270, E5P52_06600, E5S34_11300, E5S37_09185, E5S39_09190, E5S42_08280, E5S44_11235, E5S45_10170, E5S54_06815, E5S61_12055, EBP16_11825, GAJ26_06090, GKF89_26985, GRW57_20865, GUC01_13975, HHH44_000669, J4S20_001276, NCTC10418_00491, NCTC10865_00468, NCTC13127_00609
Length: 88 residues
Disorder content (fraction disordered): 0.5113636363636364
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 73, 44, 44, 44, 44, 44
Curated region end positions: 88, 88, 88, 88, 88, 88
Curated region terms: disorder, disorder, disorder to order, protein binding, protein binding, toxin sequestering activity
Domain/feature annotations: Antitoxin TacA 1-like
Cross-references: PDB:6GTO, PDB:6GTQ, PDB:6GTR, PDB:6GTS
Sequence:
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRVILNEESWTRVMDALSNPPSPGEKLKRAAKRLQGM
Protein: Division mal foutue 1 protein
UniProt accession: P78953
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Taphrinomycotina, Schizosaccharomycetes, Schizosaccharomycetales, Schizosaccharomycetaceae, Schizosaccharomyces
Gene names: SPCC4B3.15, dmf1, mid1
Length: 920 residues
Disorder content (fraction disordered): 0.49130434782608695
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 452, 452, 452, 308, 452, 452, 452, 452
Curated region terms: disorder, disorder, disorder, disorder, disorder, molecular condensate scaffold activity, protein binding, protein binding
Sequence:
MKEQEFSYREAKDVSLDSKGLENSFLSSPNREKTPLFFEGNSNETSGYDQTKNFTHGDGDMSLGNLSELNVATDLLESLDLRSMYMHGYGHLDSSFSSQHSPDNRKRMSSTSVFKRINSEEEGRIPSLTYSAGTMNSTSSSTASLKGADIVADYETFNPDQNLAELSFDRSKSSRKRAVEVAEFSRAKTMSPLEYTVQHPYQSHNELSTNPARARAGSVPNLARIPSDVKPVPPAHLSASSTVGPRILPSLPKDTTEDNPALERVETTASLDMDYKPLEPLAPIQEAPVEDTSEPFSSVPEATLDDSDISTESLRKKVLAKMEAKRISSGSSYASTLRKVYDFSELSLPTNGKDYDELYLQSSRNSEPEISTIINDSLQQENMDEDISATSIPKSQAAYGHGSVTYHEVPRYNLTSASVGYSISSQRGRIKSSSTIDNLSAILSSEDLRHPSMQPVPGTKRTYSNYCENEPNKSSQSLVSSESHNVEGWNYSETGTVGFYDPSAEISASIDELRQSTPVARDSELLSRAHSFDLNRLDLPSQDKSTSYEVPNGTENQSPRPVTSLGFVNETFFEEKPKAPLPLGRFYIHLNSILNISISEVHSPIKIIVNTPTQNMQLPWQAVNGNNRLDHDFAFHVDDNFKVSFMFLDIPIEDKSNGSKGVSATKDVSNGKPAETKSKARKFFDKLFNRRKKRKLNKAAAVENSKAKKSVVIKKVSGTATLNLGNVKDSCFGKAFNVEIPIISRGFLEAIPVKINSIGKRTLGNLTLTCLYIPELSVPEQELPFTLEQATMDLRHVRSNYLYNEGYLYRLEDSSIRRRFVVLRSKQLNFYAEKGGQYLDTFQLSKTVVSIPMVNFSEAVSNLGLVAGILATSVDRRHVQLFADSKKVCQKWLQVMNSRSFALDRGTEKLWLQEYVNFMA
Protein: Vacuolar protein sorting-associated protein 75
UniProt accession: P53853
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: N0890, VPS75, YNL246W
Length: 264 residues
Disorder content (fraction disordered): 0.1477272727272727
Curated region start positions: 226, 226, 226
Curated region end positions: 264, 264, 264
Curated region terms: disorder, protein binding, protein folding chaperone
Domain/feature annotations: Nucleosome assembly protein (NAP)
Cross-references: PDB:6O22
Sequence:
MMSDQENENEHAKAFLGLAKCEEEVDAIEREVELYRLNKMKPVYEKRDAYIDEIAEFWKIVLSQHVSFANYIRASDFKYIDTIDKIKVEWLALESEMYDTRDFSITFHFHGIEGDFKEQQVTKVFQIKKGKDDQEDGILTSEPVPIEWPQSYDSINPDLIKDKRSPEGKKKYRQGMKTIFGWFRWTGLKPGKEFPHGDSLASLFSEEIYPFCVKYYAEAQRDLEDEEGESGLSADGDSEDDDGSLGEVDLPLSDEEPSSKKRKV
Protein: Dynactin subunit 1
UniProt accession: P28023
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Dctn1
Length: 1280 residues
Disorder content (fraction disordered): 0.0796875
Curated region start positions: 108, 108, 108, 115, 132, 1, 1, 1
Curated region end positions: 191, 191, 191, 145, 152, 18, 18, 18
Curated region terms: disorder, protein binding, protein binding, molecular adaptor activity, molecular function regulator, disorder, molecular adaptor activity, protein binding
Domain/feature annotations: CAP-Gly domain, Dynein associated protein
Sequence:
MAQSKRHMYNRTPSGSRMSTEASARPLRVGSRVEVIGKGHRGTVAYVGATLFATGKWVGVILDEAKGKNDGTVQGRKYFTCDEGHGIFVRQSQIQVFEDGADTTSPETPDSSASKILKREGADAAAKTSKLRGLKPKKAPTARKTTTRRPKPTRPASTGVAGPSSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTPALTSPGAAPPLPSPSKEEEGLRDQVRDLEEKLETLRLKRSEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEAKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVNRELTNQQEASVERQQQPPPETFDFKIKFAETKAHAKAIEMELRQMEVAQANRHMSLLTAFMPDSFLRPGGDHDCVLVLLLMPRLICKAELIRKQAQEKFDLSENCSERPGLRGAAGEQLSFAAGLVYSLSLLQATLHRYEHALSQCSVDVYKKVGSLYPEMSAHERSLDFLIELLHKDQLDETVNVEPLTKAIKYYQHLYSIHLAEQPEESTMQLADHIKFTQSALDCMSVEVGRLRAFLQGGQEATDIALLLRDLETSCSDIRQFCKKIRRRMPGTDAPGIPAALAFGSQVSDTLLDCRKHLTWVVAVLQEVAAAAAQLIAPLAENEGLPVAALEELAFKASEQIYGSPSSSPYECLRQSCSILISTMNKLATAMQEGEYDAERPPSKPPPVEPWPAALRAEITDAEGLGLKLEDRETVIKELKKSLKIKGEELSEANVRLSLLEKKLDSAAKDADERIEKVQTRLEETQTLLRKKEKEFEETMDALQADIDQLEAEKTELKQRLNSQSKRTIEGLRGPPPSGIATLVSGIAGEEQQRGGTPGQAPGALPGPGPVKDSPLLLQQISAMRLHISQLQHENSILRGAQMKASLAALPPLHVAKFSLPPHEGPGGNLLSGALYRKTSQLLEKLNQLSTYTHVVDITRSSPACKSPSAQLMEQVAQLKSLSDTIEKLKDEVLKETVTQRPGATVPTDFATFPSSAFLRAKEEQQDDTVYMGKVTFSCAAGLGQRHRLVLTQEQLHQLHGRLIS
Protein: Synaptopodin
UniProt accession: Q8N3V7
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIAA1029, SYNPO
Length: 929 residues
Disorder content (fraction disordered): 1
Curated region start positions: 545, 545, 545, 1
Curated region end positions: 613, 613, 613, 929
Curated region terms: disorder, disorder, protein binding, disorder
Sequence:
MLGPHLPPPPLAPSEGRPTPCAFQIPDGSYRCLALEAEESSGEEGLQGEVGPTDLEEDEGVSRSGDDSACRVTQGTPQLPKALGIQPPSCSREEQGASQHDDRASQDWDVVKAGQMMTASPSPGPGPRVAQKPALGRSTSLTEKDLKEAKARSQQIAAQLTTPPSSNSRGVQLFNRRRQRVNEFTLESHGQRGQKPSQESLRVLPSSLPGHAPGLSLSSTSLPEPGPPRHPSPQSPDRGVPGHSMEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQVWKPSFCFK