Protein: Core protein precursor
UniProt accession: Q91AU0
Organism: Hepatitis C virus subtype 1b
Taxonomy: Viruses, Riboviria, Orthornavirae, Kitrinoviricota, Flasuviricetes, Amarillovirales, Flaviviridae, Hepacivirus
Length: 3010 residues
Disorder content (fraction disordered): 0.060132890365448506
Dataset labels: Viral proteins
Curated region start positions: 2223, 2331, 2331, 2331, 2379
Curated region end positions: 2314, 2419, 2419, 2419, 2398
Curated region terms: disorder, disorder, protein binding, disorder, protein sequestering activity
Domain/feature annotations: Viral RNA dependent RNA polymerase, Hepatitis C virus non-structural protein NS4b, Hepatitis C virus non-structural protein NS4a, Hepatitis C virus non-structural 5a protein membrane anchor, Hepatitis C virus non-structural protein NS2, Hepatitis C virus envelope glycoprotein E1, Hepatitis C virus core protein, Hepatitis C virus capsid protein, Hepatitis C virus non-structural protein E2/NS1, Hepatitis C virus NS3 protease, Hepatitis C virus non-structural 5a zinc finger domain, Hepatitis C virus non-structural 5a domain 1b, HCV NS5a protein C-terminal region, NS3 RNA helicase, C-terminal helical domain
Sequence:
MSTIPKPQRKTKRNTYRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGWAWAQPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPIDPRRRSRNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDGVNYATGNLPGCSFSIFLLALLSCLTIPASAYEVRNASGVYHVTNDCSNSSIVYEAADIIMHTPGCVPCVRENNSSRCWVALTPTLAARNLSVPTTTIRRHVDLLVGAAAFCSAMYVGDLCGSVLLVSQLFTLSPRQHETVQDCNCSLYPGHVTGHRMAWDMMMNWSPTTALVLSQILRIPQTIVDMVAGAHWGVLAGIAYYSMVGNWAKVLVVMLLFAGVDGHTQVMGGSQASTINTLTGIFSPGAKQKIQLINTNGSWHINRTALNCNDSLNTGFLAALFYTHSFNSSGCLERMASCRPIDKFDQGWGPITYDEGPDLDQRPYCWHYAPRSCGIVPASQVCGPVYCFTPSPVVVGTTDRTGAPTYRWGENETDVLILNNTRPPQGNWFGCTWMNSTGFTKTCGGPPCNIGGAGNNTLVCPTDCFRKHPEATYTKCGSGPWLTPRCMVDYPYRPWHYPCTVNFTIFKVRMYVGGVEHRLNAARNWTRGERCDLEDRDRSELSPLLLSTTEWQILPCSFTTLPALSTGLIHLHQNIVDVQYLYGIGSVVVSLVIKWEYVLLSFFLLADARVCACLWMMLLIAQAEAALENLVVLNAASVAGAHGILTFLVFFCAAWYIKGRLVPGAAYAFYGVWPLLLLLLALPPRAYAMDREMAASCGGAVFIGLVLLTLSPHYKVFLARLIWWLQYFTTRAEAILHVWVPPLNVRGGRDAVILLTCAVHPDLIFDITKLLLAVLGPLMVFLAGITRVPYFVRAQGLIRACALARKVAGGHYIQMALMKLAALTGTYLYDHLTPLRDWAHAGLRDLAVAVEPVVFSDMETKIITWGADTAACGDIILGLPVSARRGREILLGPADSLEGQGWRLLAPITAYSQQTRGLLGCIITSLTGRDKNQVEGEVQVVSTATQSFLATCVNGVCWTVFHGAGSKTLAGPKGPITQMYTNVDQDLVGWQAPPGARSLTPCTCGSSDLYLVTRHADVIPVRRRGDNRGSLLSPRPVSYLKGSSGGPLLCPSGHAVGIFRAAVCTRGVAKAVDFIPVESMETTMRSPVFTDNSSPPAVPQTFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGTYMSKAYGVDPNIRTGVRTITTGAPITYSTYGKFLADGGCSGGAYDIIMCDECHSTDSTTVLGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEIALSNTGEIPFYGKAIPIETIKGGRHLIFCHSKKKCDELAAKLSGLGLNAVAYYRGLDVSVIPTSGDVVVVATDALMTGFTGDSDSVIDCNTCVTQTVDFSLDPTFTIETTTVPQDAVSRSQRRGRTGRGRGGIYRFVTPGERPSGMFDSSVLCECYDAGCAWYELTPAETSVRLRAYLNTPGLPVCQDHLEFWESVFTGLTHIDAHFLSQTKQAGDNFPYLVAYQATVCARAQAPPPSWDQMWKSLIRLKPTLHGPTPLLYRLGTVQSEITLTHPVTKYIMACMSADLEVVTSTWVLVSGVLAALAAYCLTTGSVVIVGRIILSGKPAVIPDREVLYREFDEMEECASHLPYIEQGMQLAEQFKQKALGLLQTATKQAEAAAPVVESKWRALEAFWAKHMWNFISGIQYLAGLSTLHGNPAIASLMAFTASITSPLTTQHTLLFNILGGWVAAQLAPPSAASAFVGAGIAGAAVGSIGLGKVLVDVLAGYGAGVAGALVAFKVMSGEVPSTEDLVNLLPAVLSPGALVVGVVCAAILRRHVGPGEGAVQWMNRLIAFASRGNHVSPTHYVPESDAAARVTQILSSLTVTQLLRRLHQWINEDCSTPCSGSWLRDVWDWICTVLTDFKTWLQSKLLPRLPGVPFFSCQRGYRGVWRGDGIMQTTCPCGAQISGHVKNGSMRIVGPRSCSNTWHGTFPINAYTTGPCTPAPAPNYSRALWRVAAEEYVEVTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFQVGLNQYLVGSQLPCEPEPDVAVLTSMLTDPSHITAETAKRRLDRGSPPSLASSSASQLSAPSLKATCTTRHDSPDAGLIEANLLWRQEMGGNITRVESENKVVILDSFEPLRAEEDEREVSVPAEILRKSRKFPRAMPIWARPDYNPPLLESWKNPDYVPPVVHGCPLPPIKGPPIPPPRRKRTVVLTESTVSSALAELATKTFGSSGSSAVDSGTASAPPDQPSDNGDAGSDAESYSSMPPLEGEPGDPDLSDGSWSTVSEEASEDVVCCSMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSASQRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSKFGYGAKDVRNLSSKAVNHIRSVWKDLLEDTETPIDTTIMAKNEVFCVQPEKGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQAVMGSSYGFQYSPGQRVEFLVNAWKSKKSPMGFAYDTRCFDSTVTESDIRVEESIYQCCDLVPEARQAIRSLTERLYVGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKASAACRAAKLQDCTMLVCGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGAYYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRAWRHRARSVRAKLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGWFVAGYGGGDIYHSLSRARPRWFMLCLPLLSVGVGINLLPNR