LiteFold/DisProt huggingface dataset:
Protein: ATP-binding cassette sub-family C member 8
UniProt accession: Q09427
Organism: Cricetus cricetus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Cricetidae, Cricetinae, Cricetus
Gene names: ABCC8, SUR
Length: 1582 residues
Disorder content (fraction disordered): 0.07711757269279393
Curated region start positions: 928, 1319, 747, 928, 1319
Curated region end positions: 1000, 1343, 770, 1000, 1343
Curated region terms: disorder, disorder, disorder, flexible linker, flexible linker
Domain/feature annotations: ABC transporter type 1, transmembrane domain, ABC transporter type 1, transmembrane domain, P-loop containing nucleotide triphosphate hydrolases, P-loop containing nucleotide triphosphate hydrolases, ABC transporter, ABC transporter, ABC transporter transmembrane region, ABC transporter transmembrane region
Cross-references: PDB:5TWV
Sequence:
MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDGVTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFPKLLIALLIYWTLAFITKTIKFVKFYDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIAKLPIAMRALTNYQRLCVAFDAQARKDTQSPQGARAIWRALCHAFGRRLILSSTFRILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVSSQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHMSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWTMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRTTLEHSNERLKQTNEMLRGMKLLKLYAWESIFCSRVEVTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDLSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVPLKVVNRKRPAREEVRDLLGPLQRLAPSMDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSNLPDSEGEDPSSPERETAAGSDIRSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQQTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKASEPSQGLPRAMSSRDGLLLDEEEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSPAARNCSLSQECDLDQSVYAMVFTLLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLVSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVCMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHALLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNTLISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPETLLSQKDSVFASFVRADK
Protein: Elongin-C
UniProt accession: Q03071
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: ELC1, YPL046C
Length: 99 residues
Disorder content (fraction disordered): 0.23232323232323232
Curated region start positions: 77
Curated region end positions: 99
Curated region terms: disorder
Domain/feature annotations: Potassium Channel Kv1.1; Chain A, Skp1 family, tetramerisation domain
Sequence:
MSQDFVTLVSKDDKEYEISRSAAMISPTLKAMIEGPFRESKGRIELKQFDSHILEKAVEYLNYNLKYSGVSEDDDEIPEFEIPTEMSLELLLAADYLSI
Protein: Parvalbumin beta-1
UniProt accession: E1UJ20
Organism: Oncorhynchus kisutch
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Actinopterygii, Neopterygii, Teleostei, Protacanthopterygii, Salmoniformes, Salmonidae, Salmoninae, Oncorhynchus
Gene names: LOC109886728, pvalb1
Length: 109 residues
Disorder content (fraction disordered): 0.9908256880733946
Curated region start positions: 2, 2, 2, 2
Curated region end positions: 109, 109, 109, 109
Curated region terms: disorder, molten globule to order, disorder, disorder
Domain/feature annotations: EF-hand, EF-hand domain pair
Sequence:
MACAHLCKEADIKAALEACKAADTFNFKTFFHTIGFASKSADDVKKAFKVIDQDASGFIEVEELKLFLQNFCPNARVLTDAETKAFLKAGDADGDGMIGIDEFAVLVKQ
Protein: DNA-directed RNA polymerase II subunit RPB1
UniProt accession: P04052
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG1554, RpII215
Length: 1887 residues
Disorder content (fraction disordered): 0.04398516163222046
Curated region start positions: 1657
Curated region end positions: 1739
Curated region terms: disorder
Domain/feature annotations: RNA polymerase Rpb1, domain 3, 1.10.132.30, 3.30.1360.140, 2.40.40.20, 1.10.150.390, RNA polymerase ii, RNA polymerase II, clamp domain, RNA polymerase II, clamp domain, RNA polymerase Rpb1, domain 2, RNA polymerase Rpb1, domain 3, RNA polymerase Rpb1, domain 7, RNA polymerase Rpb1, domain 6, RNA polymerase Rpb1, domain 1, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 4
Sequence:
MSTPTDSKAPLRQVKRVQFGILSPDEIRRMSVTEGGVQFAETMEGGRPKLGGLMDPRQGVIDRTSRCQTCAGNMTECPGHFGHIDLAKPVFHIGFITKTIKILRCVCFYCSKMLVSPHNPKIKEIVMKSRGQPRKRLAYVYDLCKGKTICEGGEDMDLTKENQQPDPNKKPGHGGCGHYQPSIRRTGLDLTAEWKHQNEDSQEKKIVVSAERVWEILKHITDEECFILGMDPKYARPDWMIVTVLPVPPLAVRPAVVMFGAAKNQDDLTHKLSDIIKANNELRKNEASGAAAHVIQENIKMLQFHVATLVDNDMPGMPRAMQKSGKPLKAIKARLKGKEGRIRGNLMGKRVDFSARTVITPDPNLRIDQVGVPRSIAQNLTFPELVTPFNIDRMQELVRRGNSQYPGAKYIVRDNGERIDLRFHPKSSDLHLQCGYKVERHLRDDDLVIFNRQPTLHKMSMMGHRVKVLPWSTFRMNLSCTSPYNADFDGDEMNLHVPQSMETRAEVENIHITPRQIITPQANKPVMGIVQDTLTAVRKMTKRDVFITREQVMNLLMFLPTWDAKMPQPCILKPRPLWTGKQIFSLIIPGNVNMIRTHSTHPDEEDEGPYKWISPGDTKVMVEHGELIMGILCKKSLGTSAGSLLHICFLELGHDIAGRFYGNIQTVINNWLLFEGHSIGIGDTIADPQTYNEIQQAIKKAKDDVINVIQKAHNMELEPTPGNTLRQTFENKVNRILNDARDKTGGSAKKSLTEYNNLKAMVVSGSKGSNINISQVIACVGQQNVEGKRIPYGFRKRTLPHFIKDDYGPESRGFVENSYLAGLTPSEFYFHAMGGREGLIDTAVKTAETGYIQRRLIKAMESVMVNYDGTVRNSVGQLIQLRYGEDGLCGELVEFQNMPTVKLSNKSFEKRFKFDWSNERLMKKVFTDDVIKEMTDSSEAIQELEAEWDRLVSDRDSLRQIFPNGESKVVLPCNLQRMIWNVQKIFHINKRLPTDLSPIRVIKGVKTLLERCVIVTGNDRISKQANENATLLFQCLIRSTLCTKYVSEEFRLSTEAFEWLVGEIETRFQQAQANPGEMVGALAAQSLGEPATQMTLNTFHFAGVSSKNVTLGVPRLKEIINISKKPKAPSLTVFLTGGAARDAEKAKNVLCRLEHTTLRKVTANTAIYYDPDPQRTVISEDQEFVNVYYEMPDFDPTRISPWLLRIELDRKRMTDKKLTMEQIAEKINVGFGEDLNCIFNDDNADKLVLRIRIMNNEENKFQDEDEAVDKMEDDMFLRCIEANMLSDMTLQGIEAIGKVYMHLPQTDSKKRIVITETGEFKAIGEWLLETDGTSMMKVLSERDVDPIRTSSNDICEIFQVLGIEAVRKSVEKEMNAVLQFYGLYVNYRHLALLCDVMTAKGHLMAITRHGINRQDTGALMRCSFEETVDVLMDAAAHAETDPMRGVSENIIMGQLPKMGTGCFDLLLDAEKCRFGIEIPNTLGNSMLGGAAMFIGGGSTPSMTPPMTPWANCNTPRYFSPPGHVSAMTPGGPSFSPSAASDASGMSPSWSPAHPGSSPSSPGPSMSPYFPASPSVSPSYSPTSPNYTASSPGGASPNYSPSSPNYSPTSPLYASPRYASTTPNFNPQSTGYSPSSSGYSPTSPVYSPTVQFQSSPSFAGSGSNIYSPGNAYSPSSSNYSPNSPSYSPTSPSYSPSSPSYSPTSPCYSPTSPSYSPTSPNYTPVTPSYSPTSPNYSASPQYSPASPAYSQTGVKYSPTSPTYSPPSPSYDGSPGSPQYTPGSPQYSPASPKYSPTSPLYSPSSPQHSPSNQYSPTGSTYSATSPRYSPNMSIYSPSSTKYSPTSPTYTPTARNYSPTSPMYSPTAPSHYSPTSPAYSPSSPTFEESED
Protein: Syndecan-4
UniProt accession: P31431
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SDC4
Length: 198 residues
Disorder content (fraction disordered): 0.1414141414141414
Dataset labels: Cancer-related proteins, Extracellular matrix proteins
Curated region start positions: 171
Curated region end positions: 198
Curated region terms: disorder
Domain/feature annotations: Syndecan domain
Sequence:
MAPARLFALLLFFVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
Protein: P antigen family member 4
UniProt accession: O60829
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GAGEC1, JM27, PAGE4
Length: 102 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 40, 49, 7, 7, 49, 69
Curated region end positions: 102, 102, 102, 102, 102, 70, 53, 11, 11, 53, 73
Curated region terms: disorder, nucleic acid binding, disorder, nucleic acid binding, disorder, disorder to order, phosphorylation display site, phosphorylation display site, phosphorylation display site, phosphorylation display site, protein binding
Domain/feature annotations: GAGE protein
Cross-references: BMRB:26544, BMRB:26545
Sequence:
MSARVRSRSRGRGDGQEAPDVVAFVAPGESQQEEPPTDNQDIEPGQEREGTPPIEERKVEGDCQEMDLEKTRSERGDGSDVKEKTPPNPKHAKTKEAGDGQP
Protein: Protein lin-2
UniProt accession: P54936
Organism: Caenorhabditis elegans
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Nematoda, Chromadorea, Rhabditida, Rhabditina, Rhabditomorpha, Rhabditoidea, Rhabditidae, Peloderinae, Caenorhabditis
Gene names: F17E5.1, lin-2
Length: 961 residues
Disorder content (fraction disordered): 0.06763787721123829
Curated region start positions: 423, 423, 423
Curated region end positions: 487, 487, 487
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: SH3 Domains, Phosphorylase Kinase; domain 1, P-loop containing nucleotide triphosphate hydrolases, EF-hand, 2.30.42.10, Transferase(Phosphotransferase) domain 1, SH3 domain, Protein kinase domain, PDZ domain, Guanylate kinase, L27 domain, L27 domain
Sequence:
MRELDPDESNLLLDEQLSIRDVIEQGPFSNVYRILHGPSNRKFLLRSINLNLFRQHTGLGFEEIDEEIRICQNLQHPYICRLEKTINSVHYRHIIFENMEGNDICFEIVQRASNGFVFSEYVVSHYTRQLLDALDYCHTRKIVHRDVRPHNLVLASKDTSAPLKLCGFGVAKDLSEIGGSMACGRVGVPQFMAPEIVRKDRVSCSSDIWSSGVVLFLLLAGRLPFSGSTSDIYERIMQTDVDVDGYMPNISESARNLVRRMLNADPSKRISAKEALNHEWIRDKEHMASRKHMNDVIDQMRRYNESRKLKSNVLSAVNSGRFDETTPRQDTPQTAFVDGSSPGGDCCHRGESSSNDAAEPPADKDLSGAYKVLGSLDAINSLLDPNSYKPGSTTFQKIHDDGSVRNLLRLYDKIKALPCEPVVTEVDTSTLRKETLNQIDGLLGPSPEALELRQLLNSPHLASCVQALDVVVCEIRDPKNEASGSGDKEGNCVSSDPAPAYLNGGVLPLGAQRAGTSFEHFNQSAVHTSYDEEEEELYDCMSRLRLVQFQKDTQEPMGITLKVNEDGRCFVARIMHGGMIHRQATLHVGDEIREINGMSVANRSVESLQEMLRDARGQVTFKIIPSYRSAPPACEIFVRAQFDYEPSQDDLIPCPQAGIPFKTGDILQVISKDDHNWWQARFVSSFPSIGNSSNAQRSNQQQVAGLIPSPELQEWRTACLAMERSKNTCNTHCMWFNKKKKYYTTKYLQKHSALFDQLDLVTYEEVMRLSQYRRKTLVLLGAHGVGRRHIKNTLIHRHPNRFAYPIPHTTRPPRKDEVDGKHYYFVTNEQMMADIQNNEYLEYGTHEESMYGTKLETIRNIHKSGKIAILDVEPQALKVLRTAEYSPFVVFIAAPNLQGMQDPDGSLEKLLNESDVLRQAFGHLFDFIITNSDIDDTIAQLERLVEKLPAYPQWLPVTWVY
Protein: LIN-7
UniProt accession: P90976
Organism: Caenorhabditis elegans
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Nematoda, Chromadorea, Rhabditida, Rhabditina, Rhabditomorpha, Rhabditoidea, Rhabditidae, Peloderinae, Caenorhabditis
Length: 297 residues
Disorder content (fraction disordered): 0.2222222222222222
Curated region start positions: 115, 115, 115
Curated region end positions: 180, 180, 180
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: 2.30.42.10, L27 domain, PDZ domain, L27 domain
Cross-references: PDB:1zl8
Sequence:
MGLKGFTGSFQQIRGLLRPPKNLPFRGIFRKDGEVVRKDDLLVNQFKMNYHPGLNVYYENDRGERLLRAHCDGIVRISQEKCDPDYEIEEMKGYEYRKDVDLYKMTFNMDNPDGPNLERDVQRILELMEHVQKTGEVNNAKLASLQQVLQSEFFGAVREVYETVYESIDADTTPEIKAAATAKATVAAFAAAEGHAHPRIVELPKTDQGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGNVEAECHEKAVDLLKSAVGSVKLVIRYMPKLLDEMERRFERQRIP
Protein: TCP pilus virulence regulatory protein
UniProt accession: A5F384
Organism: Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Vibrionales, Vibrionaceae, Vibrio
Gene names: VC0395_A0363, VC395_0854, tcpN, toxT
Length: 276 residues
Disorder content (fraction disordered): 0.036231884057971016
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 101, 101, 101
Curated region end positions: 110, 109, 110
Curated region terms: disorder, limited proteolysis display site, molecular function regulator
Domain/feature annotations: Homeodomain-like, ToxT, HTH1 motif, 2.60.120.810, Bacterial regulatory helix-turn-helix proteins, AraC family, ToxT, N-terminal cupin-like domain
Cross-references: PDB:3GBG
Sequence:
MIGKKSFQTNVYRMSKFDTYIFNNLYINDYKMFWIDSGIAKLIDKNCLVSYEINSSSIILLKKNSIQRFSLTSLSDENINVSVITISDSFIRSLKSYILGDLMIRNLYSENKDLLLWNCEHNDIAVLSEVVNGFREINYSDEFLKVFFSGFFSKVEKKYNSIFITDDLDAMEKISCLVKSDITRNWRWADICGELRTNRMILKKELESRGVKFRELINSIRISYSISLMKTGEFKIKQIAYQSGFASVSYFSTVFKSTMNVAPSEYLFMLTGVAEK
Protein: Mu-like prophage FluMu protein gp35
UniProt accession: P44228
Organism: Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pasteurellales, Pasteurellaceae, Haemophilus
Gene names: HI_1506/HI_1507
Length: 128 residues
Disorder content (fraction disordered): 0.375
Curated region start positions: 12, 12, 54, 54
Curated region end positions: 28, 28, 84, 84
Curated region terms: disorder, DNA binding, disorder, DNA binding
Domain/feature annotations: 3.40.5.80, HeH/LEM domain, Mu-like prophage FluMu N-terminal domain
Cross-references: PDB:2OUT
Sequence:
MDKTFCVVVQNRIKEGYRRAGFSFHLGDNSLAAVSESQLAQLKADPRLVVQITETGSQEGGEGLSKEPAGSDEQKQLRADPPSTDLNTFTVEQLKAQLTERGITFKQSATKAELIALFAPADGEKSEA
Protein: Protein C-ets-1
UniProt accession: P14921
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ETS1, EWSR2
Length: 441 residues
Disorder content (fraction disordered): 0.09750566893424036
Curated region start positions: 276, 276
Curated region end positions: 318, 318
Curated region terms: disorder, nucleic acid binding
Domain/feature annotations: Transcription Factor, Ets-1, Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Ets-domain, Sterile alpha motif (SAM)/Pointed domain, Ets1 N-terminal flanking region of Ets domain
Cross-references: PDB:3WTS
Sequence:
MKAAVDLKPTLTIIKTEKVDLELFPSPDMECADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLEILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSFITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMCMGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKPDADE
Protein: Seed maturation protein
UniProt accession: Q2Q4X9
Organism: Medicago truncatula
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, fabids, Fabales, Fabaceae, Papilionoideae, 50 kb inversion clade, NPAAA clade, Hologalegina, IRL clade, Trifolieae, Medicago
Gene names: PM25
Length: 260 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 260, 260, 260, 260, 260, 260, 260, 260
Curated region terms: disorder, disorder, disorder to order, protein stabilization, stress granule disassembly, stress granule disassembly, protein stabilization, stress granule disassembly
Domain/feature annotations: Seed maturation protein, Seed maturation protein, Seed maturation protein
Sequence:
MSQEQPRRPQAGQDPIKYGDVLPVSGDLSQKPITPEDAAMMQSAESRVLGQTQPGGVASVMQSAATRNEQAGIVGHKDVTDVTGDRGVTVTETQVPGRRIITETVGGQVVGQFVEPTPVQVGLTGAVRESALTIGEALEATAHTVGDKPVEQSDASAIQAAEVRATGSNVITPGGLASMAQSAAAFNAECQREEEKIKMGNVLTGATAKLPADKAATRQDAAGVASAEMRNNPDATATPGGVAASVAAAARLNENVGNVM
Protein: Anaphase-promoting complex subunit 5
UniProt accession: Q9UJX4
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC5, APC5
Length: 755 residues
Disorder content (fraction disordered): 0.16556291390728478
Curated region start positions: 1, 1, 168, 170, 353
Curated region end positions: 26, 24, 205, 205, 413
Curated region terms: disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Tetratricopeptide repeat domain, Anaphase-promoting complex subunit 5, Anaphase-promoting complex subunit 5, Anaphase-promoting complex subunit 5, N-terminal domain
Cross-references: PDB:4UI9, PDB:5G04, PDB:5G05, PDB:5KHR, PDB:5KHU
Sequence:
MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEAVNAGVQQNNTESFAVALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLLVHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQYLASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVAKCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFRQLHQELPSHGVPLINHL
Protein: Nucleotide-binding oligomerization domain-containing protein 1
UniProt accession: Q9Y239
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CARD4, NOD1
Length: 953 residues
Disorder content (fraction disordered): 0.02938090241343127
Curated region start positions: 111
Curated region end positions: 138
Curated region terms: disorder
Domain/feature annotations: Ribonuclease Inhibitor, Ribonuclease Inhibitor, Death Domain, Fas, P-loop containing nucleotide triphosphate hydrolases, Caspase recruitment domain, NACHT domain, Leucine Rich repeat, Leucine Rich repeat, Leucine Rich repeat, Leucine Rich repeat, NLRC4 helical domain HD2, NOD2 winged helix domain
Cross-references: PDB:2B1W
Sequence:
MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF
Protein: G1/S-specific cyclin-D3
UniProt accession: P30281
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CCND3
Length: 292 residues
Disorder content (fraction disordered): 0.2054794520547945
Dataset labels: Cancer-related proteins
Curated region start positions: 255, 1, 281
Curated region end positions: 292, 22, 285
Curated region terms: disorder, disorder, phosphorylation display site
Domain/feature annotations: Cyclin-like, Cyclin-like, Cyclin, N-terminal domain, Cyclin, C-terminal domain
Cross-references: PDB:3G33
Sequence:
MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Protein: Osteopontin
UniProt accession: P10923
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Eta-1, Op, Spp-1, Spp1
Length: 294 residues
Disorder content (fraction disordered): 0.9455782312925172
Dataset labels: Extracellular matrix proteins
Curated region start positions: 17, 17
Curated region end positions: 294, 294
Curated region terms: disorder, disorder
Domain/feature annotations: Osteopontin
Sequence:
MRLAVICFCLFGIASSLPVKVTDSGSSEEKLYSLHPDPIATWLVPDPSQKQNLLAPQNAVSSEEKDDFKQETLPSNSNESHDHMDDDDDDDDDDGDHAESEDSVDSDESDESHHSDESDETVTASTQADTFTPIVPTVDVPNGRGDSLAYGLRSKSRSFQVSDEQYPDATDEDLTSHMKSGESKESLDVIPVAQLLSMPSDQDNNGKGSHESSQLDEPSLETHRLEHSKESQESADQSDVIDSQASSKASLEHQSHKFHSHKDKLVLDPKSKEDDRYLKFRISHELESSSSEVN
Protein: Splicing factor 1
UniProt accession: Q15637
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SF1, ZFM1, ZNF162
Length: 639 residues
Disorder content (fraction disordered): 0.081377151799687
Curated region start positions: 1, 1, 69, 69
Curated region end positions: 25, 25, 95, 95
Curated region terms: disorder, protein binding, disorder, phosphorylation display site
Domain/feature annotations: K Homology domain, type 1, Zinc knuckle, Splicing factor 1 helix-hairpin domain, KHDC4/BBP-like, KH-domain type I
Sequence:
MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN
Protein: F-box only protein 5
UniProt accession: Q9UKT4
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: EMI1, FBX5, FBXO5
Length: 447 residues
Disorder content (fraction disordered): 0.8970917225950783
Curated region start positions: 1, 332, 437, 305, 421, 421, 305, 321, 321, 421, 421, 338, 338, 338
Curated region end positions: 318, 355, 447, 374, 447, 447, 374, 330, 330, 447, 447, 359, 359, 359
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, protein binding, molecular function inhibitor activity, molecular function inhibitor activity, molecular function regulator, molecular function inhibitor activity, molecular function inhibitor activity, flexible linker
Domain/feature annotations: 2.20.25.20, 1.20.1280.50, F-box domain, IBR domain
Cross-references: PDB:2M6N, PDB:4UI9
Sequence:
MSRRPCSCALRPPRCSCSASPSAVTAAGRPRPSDSCKEESSTLSVKMKCDFNCNHVHSGLKLVKPDDIGRLVSYTPAYLEGSCKDCIKDYERLSCIGSPIVSPRIVQLETESKRLHNKENQHVQQTLNSTNEIEALETSRLYEDSGYSSFSLQSGLSEHEEGSLLEENFGDSLQSCLLQIQSPDQYPNKNLLPVLHFEKVVCSTLKKNAKRNPKVDREMLKEIIARGNFRLQNIIGRKMGLECVDILSELFRRGLRHVLATILAQLSDMDLINVSKVSTTWKKILEDDKGAFQLYSKAIQRVTENNNKFSPHASTREYVMFRTPLASVQKSAAQTSLKKDAQTKLSNQGDQKGSTYSRHNEFSEVAKTLKKNESLKACIRCNSPAKYDCYLQRATCKREGCGFDYCTKCLCNYHTTKDCSDGKLLKASCKIGPLPGTKKSKKNLRRL