LiteFold/DisProt huggingface dataset:
Protein: Nuclear factor erythroid 2-related factor 2
UniProt accession: Q60795
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Nfe2l2, Nrf2
Length: 597 residues
Disorder content (fraction disordered): 0.16415410385259632
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 98, 98, 98, 98
Curated region terms: disorder, molecular function regulator, disorder to order, protein binding
Domain/feature annotations: Transcription factor, Skn-1-like, DNA-binding domain, bZIP Maf transcription factor
Sequence:
MMDLELPPPGLQSQQDMDLIDILWRQDIDLGVSREVFDFSQRQKDYELEKQKKLEKERQEQLQKEQEKAFFAQFQLDEETGEFLPIQPAQHIQTDTSGSASYSQVAHIPKQDALYFEDCMQLLAETFPFVDDHESLALDIPSHAESSVFTAPHQAQSLNSSLEAAMTDLSSIEQDMEQVWQELFSIPELQCLNTENKQLADTTAVPSPEATLTEMDSNYHFYSSISSLEKEVGNCGPHFLHGFEDSFSSILSTDDASQLTSLDSNPTLNTDFGDEFYSAFIAEPSDGGSMPSSAAISQSLSELLDGTIEGCDLSLCKAFNPKHAEGTMEFNDSDSGISLNTSPSRASPEHSVESSIYGDPPPGFSDSEMEELDSAPGSVKQNGPKAQPAHSPGDTVQPLSPAQGHSAPMRESQCENTTKKEVPVSPGHQKAPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEREKLLREKGENDRNLHLLKRRLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDTKKN
Protein: Paired box protein Pax-5
UniProt accession: Q02548
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PAX5
Length: 391 residues
Disorder content (fraction disordered): 0.12020460358056266
Dataset labels: Cancer-related proteins, NDDs-related proteins
Curated region start positions: 1, 19, 76, 76, 76, 1
Curated region end positions: 30, 30, 92, 92, 92, 18
Curated region terms: disorder, disorder to order, disorder, flexible linker, disorder to order, disorder
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, 'Paired box' domain, Paired-box protein 2 C terminal
Cross-references: BMRB:26730, BMRB:26731, PDB:1MDM
Sequence:
MDLEKNYPTPRTSRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLASPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSAAARGAAPPAAATAYDRH
Protein: Biotin carboxyl carrier protein of acetyl-CoA carboxylase
UniProt accession: P0ABD8
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3223, accB, b3255, fabE
Length: 156 residues
Disorder content (fraction disordered): 0.4935897435897436
Curated region start positions: 1, 1, 1
Curated region end positions: 77, 77, 77
Curated region terms: disorder, molecular adaptor activity, protein binding
Domain/feature annotations: 2.40.50.100, Biotin-requiring enzyme
Cross-references: PDB:4HR7
Sequence:
MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVMQQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAFIEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE
Protein: Isoform Crk-I of Adapter molecule crk
UniProt accession: P46108-2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CRK
Length: 204 residues
Disorder content (fraction disordered): 0.06372549019607843
Curated region start positions: 121, 121
Curated region end positions: 133, 133
Curated region terms: disorder, flexible linker
Cross-references: PDB:2EYY
Sequence:
MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVSRSRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNAEDSEGKRGMIPVPYVEKYRPASASVSALIGGR
Protein: Mu-type opioid receptor
UniProt accession: P42866
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Mor, Oprm, Oprm1
Length: 398 residues
Disorder content (fraction disordered): 0.2236180904522613
Curated region start positions: 1, 361
Curated region end positions: 51, 398
Curated region terms: disorder, disorder
Domain/feature annotations: Rhodopsin 7-helix transmembrane proteins, 7 transmembrane receptor (rhodopsin family)
Cross-references: PDB:4DKL
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
Protein: Thrombin inhibitor madanin 1
UniProt accession: Q86FP9
Organism: Haemaphysalis longicornis
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Chelicerata, Arachnida, Acari, Parasitiformes, Ixodida, Ixodoidea, Ixodidae, Haemaphysalinae, Haemaphysalis
Length: 79 residues
Disorder content (fraction disordered): 0.759493670886076
Curated region start positions: 20, 50, 50, 50, 50
Curated region end positions: 79, 73, 73, 73, 73
Curated region terms: disorder, disorder, molecular function inhibitor activity, protein binding, disorder to order
Domain/feature annotations: Thrombin inhibitor Madanin
Cross-references: PDB:5L6N
Sequence:
MKHFAILILAVVASAVVMAYPERDSAKEGNQEQERALHVKVQKRTDGDADYDEYEEDGTTPTPDPTAPTAKPRLRGNKP
Protein: Envelope glycoprotein gp160
UniProt accession: P04578
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate HXB2)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: env
Length: 856 residues
Disorder content (fraction disordered): 0.09579439252336448
Dataset labels: Viral proteins
Curated region start positions: 127, 127, 127, 398, 127
Curated region end positions: 196, 196, 196, 409, 196
Curated region terms: disorder, protein binding, evasion of host immune response, disorder, viral entry into host cell
Domain/feature annotations: Human immunodeficiency virus 1, Gp160, envelope glycoprotein, Human immunodeficiency virus 1, Gp160, envelope glycoprotein, 1.10.287.210, Single helix bin, Envelope glycoprotein GP120, Retroviral envelope protein
Cross-references: PDB:1G9M
Sequence:
MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCVKLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLDIIPIDNDTTSYKLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPNNNTRKRIRIQRGPGRAFVTIGKIGNMRQAHCNISRAKWNNTLKQIASKLREQFGNNKTIIFKQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTEGSNNTEGSDTITLPCRIKQIINMWQKVGKAMYAPPISGQIRCSSNITGLLLTRDGGNSNNESEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKLICTTAVPWNASWSNKSLEQIWNHTTWMEWDREINNYTSLIHSLIEESQNQQEKNEQELLELDKWASLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSFQTHLPTPRGPDRPEGIEEEGGERDRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTRIVELLGRRGWEALKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEVVQGACRAIRHIPRRIRQGLERILL
Protein: Thrombin inhibitor madanin 2
UniProt accession: Q86FP8
Organism: Haemaphysalis longicornis
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Chelicerata, Arachnida, Acari, Parasitiformes, Ixodida, Ixodoidea, Ixodidae, Haemaphysalinae, Haemaphysalis
Length: 80 residues
Disorder content (fraction disordered): 0.7625
Curated region start positions: 20, 20, 20
Curated region end positions: 80, 80, 80
Curated region terms: disorder, molecular function inhibitor activity, protein binding
Domain/feature annotations: Thrombin inhibitor Madanin
Sequence:
MKHFVILILAVVASAVVMAYPERDSAKDGNQEKERALLVKVQERYQGNQGDYDEYDQDETTPPPDPTAQTARPRLRQNQD
Protein: Photosystem I reaction center subunit V, chloroplastic
UniProt accession: P12357
Organism: Spinacia oleracea
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, Caryophyllales, Chenopodiaceae, Chenopodioideae, Anserineae, Spinacia
Gene names: PSAG
Length: 167 residues
Disorder content (fraction disordered): 0.5868263473053892
Curated region start positions: 73, 70
Curated region end positions: 167, 164
Curated region terms: disorder, disorder
Domain/feature annotations: Chlorophyll a-b binding protein like, Photosystem I psaG / psaK
Cross-references: PDB:2WSC:G, PDB:4XK8:G
Sequence:
MAAATASLSSTLLAPCSSKQPQPQQQHQHQQLKCKSFSGLRPLKLNISSNNSSSSLSMSSARRSMTCRAELSPSLVISLSTGLSLFLGRFVFFNFQRENMAKQVPEQNGMSHFEAGDTRAKEYVSLLKSNDPVGFNIVDVLAWGSIGHIVAYYILATASNGYDPSFF
Protein: Sulfate adenylyltransferase subunit 2
UniProt accession: Q87WW0
Organism: Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: PSPTO_4433, cysD
Length: 305 residues
Disorder content (fraction disordered): 0.29180327868852457
Curated region start positions: 217, 217, 217
Curated region end positions: 305, 305, 305
Curated region terms: disorder, entropic chain, small molecule binding
Domain/feature annotations: HUPs, Phosphoadenosine phosphosulfate reductase domain
Cross-references: PDB:1ZUN
Sequence:
MVDKLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLARKAFFPGKLPFPVMHVDTRWKFQEMYRFRDQMVEEMGLDLITHINPDGVAQGINPFTHGSAKHTDIMKTEGLKQALDKHGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNVYNGNVNKGESIRVFPLSNWTELDIWQYIYLEGIPIVPLYFAAERDVIEKNGTLIMIDDERILEHLTDEEKSRIVKKKVRFRTLGCYPLTGAVESEATSLTDIIQEMLLTRTSERQGRVIDHDGAGSMEEKKRQGYF
Protein: VP4
UniProt accession: Q8QWD4
Organism: Enterovirus D68
Taxonomy: Viruses, Riboviria, Orthornavirae, Pisuviricota, Pisoniviricetes, Picornavirales, Picornaviridae, Enterovirus, Enterovirus D
Length: 69 residues
Disorder content (fraction disordered): 0.4057971014492754
Dataset labels: Viral proteins
Curated region start positions: 2
Curated region end positions: 29
Curated region terms: disorder
Domain/feature annotations: Picornavirus coat protein VP4, Picornavirus coat protein (VP4)
Cross-references: PDB:4WM7, PDB:4WM8
Sequence:
MGAQVTRQQTGTHENANIATNGSHITYNQINFYKDSYAASASKQDFSQDPSKFTEPVVEGLKAGAPVLK
Protein: Anti-sigma factor NepR
UniProt accession: A0A0H3CFC9
Organism: Caulobacter vibrioides (strain NA1000 / CB15N)
Taxonomy: Bacteria, Proteobacteria, Alphaproteobacteria, Caulobacterales, Caulobacteraceae, Caulobacter
Gene names: CCNA_03590, nepR
Length: 61 residues
Disorder content (fraction disordered): 0.3606557377049181
Curated region start positions: 1
Curated region end positions: 22
Curated region terms: disorder
Domain/feature annotations: Anti-sigma factor NepR
Cross-references: PDB:3T0Y
Sequence:
MIEHVPMEDKRKGAAALDEARLRQQAIGVKLRQMFDEVVNEPVPDEFLAILRKAERPAGGE
Protein: Uncharacterized protein YdiE
UniProt accession: P0ACX9
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1695, b1705, ydiE
Length: 63 residues
Disorder content (fraction disordered): 0.31746031746031744
Curated region start positions: 1
Curated region end positions: 20
Curated region terms: disorder
Domain/feature annotations: Complement Module, domain 1, Hemin uptake protein hemP
Cross-references: PDB:4YNX
Sequence:
MRYTDSRKLTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDHDGQEYLLRKTQAGKLLLTK
Protein: Photosystem I reaction center subunit III, chloroplastic
UniProt accession: P12355
Organism: Spinacia oleracea
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, Caryophyllales, Chenopodiaceae, Chenopodioideae, Anserineae, Spinacia
Gene names: PSAF
Length: 231 residues
Disorder content (fraction disordered): 0.3333333333333333
Curated region start positions: 1
Curated region end positions: 77
Curated region terms: disorder
Domain/feature annotations: Photosystem I PsaF, reaction centre subunit III, Photosystem I reaction centre subunit III
Cross-references: PDB:2WSC, PDB:2WSE, PDB:2WSF
Sequence:
MSFTIPTNLYKPLATKPKHLSSSSFAPRSKIVCQQENDQQQPKKLELAKVGANAAAALALSSVLLSSWSVAPDAAMADIAGLTPCKESKQFAKREKQALKKLQASLKLYADDSAPALAIKATMEKTKKRFDNYGKYGLLCGSDGLPHLIVSGDQRHWGEFITPGILFLYIAGWIGWVGRSYLIAIRDEKKPTQKEIIIDVPLASSLLFRGFSWPVAAYRELLNGELVDNNF
Protein: Universal stress protein E
UniProt accession: P0AAC0
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW1327, b1333, uspE, ydaA
Length: 316 residues
Disorder content (fraction disordered): 0.04430379746835443
Curated region start positions: 269, 269, 269
Curated region end positions: 282, 282, 282
Curated region terms: disorder, entropic chain, small molecule binding
Domain/feature annotations: 3.40.50.12370, Universal stress protein family, Universal stress protein family
Cross-references: PDB:5CB0
Sequence:
MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQEVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAVNLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGISAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD
Protein: Methane monooxygenase regulatory protein B
UniProt accession: P27356
Organism: Methylosinus trichosporium
Taxonomy: Bacteria, Proteobacteria, Alphaproteobacteria, Rhizobiales, Methylocystaceae, Methylosinus
Gene names: mmoB
Length: 138 residues
Disorder content (fraction disordered): 0.34057971014492755
Curated region start positions: 1, 1, 127
Curated region end positions: 35, 35, 138
Curated region terms: disorder, molecular function regulator, disorder
Domain/feature annotations: Monooxygenase component MmoB/DmpM, MmoB/DmpM family
Cross-references: PDB:2MOB
Sequence:
MSSAHNAYNAGIMQKTGKAFADEFFAEENQVVHESNAVVLVLMKSDEIDAIIEDIVLKGGKAKNPSIVVEDKAGFWWIKADGAIEIDAAEAGELLGKPFSVYDLLINVSSTVGRAYTLGTKFTITSELMGLDRALTDI
Protein: Translocation protein in type III secretion
UniProt accession: Q9I332
Organism: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: PA1695, pscP
Length: 369 residues
Disorder content (fraction disordered): 0.6856368563685636
Curated region start positions: 1, 1, 20, 20, 20
Curated region end positions: 253, 253, 40, 40, 40
Curated region terms: disorder, flexible N-terminal tail, disorder, localization, protein binding
Domain/feature annotations: Flagellar hook-length control protein FliK
Sequence:
MLKLNAVDTAPLVSSDTLAPLPPLRAQQIAFEQALPAHRPPAPRPPFDKGDETTEAAATADAPTSTPLADQPAAPAADRPPTIRQPPMPVAADATPTPTPTPTPTPTPTPTPTPTPTVSPSGSVARQAPAVSARVAASTQAREPASVSAPPVDEPPLVPVSSHPQIAGRTHERPQPGPGFPAKTAAEVAPTAQASVQASPPAPTAGGEGRGEERRQPGETDPSALPPDDQAPVPLPAMQTPGDRLLARLLASSGSRPLPLADLARLLDAVQGRIQVASAAESHAARLQVRLPQLGAVEVQVLHGHGQLQIEISASPGSLALLQQARGELLERLQRLHPEQPVQLTFNQQQDSGQRSRQRRYLHEEWQAE
Protein: Suppressor protein STM1
UniProt accession: P39015
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: L9634.1, MPT4, STM1, STO1, YLR150W
Length: 273 residues
Disorder content (fraction disordered): 0.5897435897435898
Curated region start positions: 85, 177, 195, 85, 142
Curated region end positions: 117, 273, 273, 121, 168
Curated region terms: disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Stm1
Cross-references: PDB:4U3M, PDB:5DC3
Sequence:
MSNPFDLLGNDVEDADVVVLPPKEIVKSNTSSKKADVPPPSADPSKARKNRPRPSGNEGAIRDKTAGRRNNRSKDVTDSATTKKSNTRRATDRHSRTGKTDTKKKVNQGWGDDKKELSAEKEAQADAAAEIAEDAAEAEDAGKPKTAQLSLQDYLNQQANNQFNKVPEAKKVELDAERIETAEKEAYVPATKVKNVKSKQLKTKEYLEFDATFVESNTRKNFGDRNNNSRNNFNNRRGGRGARKGNNTANATNSANTVQKNRNIDVSNLPSLA
Protein: ATPase inhibitor, mitochondrial
UniProt accession: P01097
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: D1305, INH1, YDL181W
Length: 85 residues
Disorder content (fraction disordered): 0.27058823529411763
Curated region start positions: 28, 28, 28, 28
Curated region end positions: 50, 50, 50, 50
Curated region terms: disorder, molecular function inhibitor activity, disorder to order, protein binding
Domain/feature annotations: Single helix bin, Mitochondrial ATPase inhibitor, IATP
Sequence:
MLPRSALARSLQLQRGVAARFYSEGSTGTPRGSGSEDSFVKRERATEDFFVRQREKEQLRHLKEQLEKQRKKIDSLENKIDSMTK
Protein: Single-stranded DNA-binding protein
UniProt accession: Q9WZ73
Organism: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomy: Bacteria, Thermotogae, Thermotogales, Thermotogaceae, Thermotoga
Gene names: TM_0604, ssb
Length: 141 residues
Disorder content (fraction disordered): 0.3120567375886525
Curated region start positions: 38, 38, 38, 109, 109, 109
Curated region end positions: 48, 48, 48, 141, 141, 141
Curated region terms: disorder, molecular function regulator, nucleic acid binding, disorder, molecular function regulator, nucleic acid binding
Domain/feature annotations: Nucleic acid-binding proteins, Single-strand binding protein family
Cross-references: PDB:1Z9F
Sequence:
MSFFNKIILIGRLVRDPEERYTLSGTPVTTFTIAVDRVPRKNAPDDAQTTDFFRIVTFGRLAEFARTYLTKGRLVLVEGEMRMRRWETPTGEKRVSPEVVANVVRFMDRKPAETVSETEEELEIPEEDFSSDTFSEDEPPF
Protein: HTH-type transcriptional activator TipA
UniProt accession: P0A4T9
Organism: Streptomyces lividans
Taxonomy: Bacteria, Actinobacteria, Streptomycetales, Streptomycetaceae, Streptomyces
Gene names: tipA
Length: 253 residues
Disorder content (fraction disordered): 0.19367588932806323
Curated region start positions: 111, 111, 111
Curated region end positions: 159, 159, 159
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: Antibiotic binding domain of TipA-like multidrug resistance regulators, 1.10.1660.10, TipAS antibiotic-recognition domain, MerR HTH family regulatory protein
Cross-references: PDB:1NY9
Sequence:
MSYSVGQVAGFAGVTVRTLHHYDDIGLLVPSERSHAGHRRYSDADLDRLQQILFYRELGFPLDEVAALLDDPAADPRAHLRRQHELLSARIGKLQKMAAAVEQAMEARSMGINLTPEEKFEVFGDFDPDQYEEEVRERWGNTDAYRQSKEKTASYTKEDWQRIQDEADELTRRFVALMDAGEPADSEGAMDAAEDHRQGIARNHYDCGYEMHTCLGEMYVSDERFTRNIDAAKPGLAAYMRDAILANAVRHTP
Protein: Polymerase cofactor VP35
UniProt accession: Q05127
Organism: Zaire ebolavirus (strain Mayinga-76)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Ebolavirus
Gene names: VP35
Length: 340 residues
Disorder content (fraction disordered): 0.08529411764705883
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 20, 20, 20, 20, 20, 26, 20, 20, 20, 20, 20, 20
Curated region end positions: 48, 48, 48, 48, 48, 36, 48, 48, 48, 48, 48, 48
Curated region terms: disorder, protein binding, protein binding, protein binding, viral transcription, disorder to order, molecular sequestering activity, protein binding, molecular sequestering activity, molecular sequestering activity, molecular sequestering activity, viral genome replication
Domain/feature annotations: Filoviridae VP35, C-terminal inhibitory domain, helical subdomain, Filoviridae VP35, C-terminal inhibitory domain, beta-sheet subdomain, Filoviridae VP35
Cross-references: PDB:4YPI
Sequence:
MTTRTKGRGHTAATTQNDRMPGPELSGWISEQLMTGRIPVSDIFCDIENNPGLCYASQMQQTKPNPKTRNSQTQTDPICNHSFEEVVQTLASLATVVQQQTIASESLEQRITSLENGLKPVYDMAKTISSLNRVCAEMVAKYDLLVMTTGRATATAAATEAYWAEHGQPPPGPSLYEESAIRGKIESRDETVPQSVREAFNNLNSTTSLTEENFGKPDISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASLAEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPSPKIDRGWVCVFQLQDGKTLGLKI
Protein: Structural polyprotein
UniProt accession: P03315
Organism: Semliki forest virus
Taxonomy: Viruses, Riboviria, Orthornavirae, Kitrinoviricota, Alsuviricetes, Martellivirales, Togaviridae, Alphavirus
Length: 1253 residues
Disorder content (fraction disordered): 0.11332801276935354
Dataset labels: Viral proteins
Curated region start positions: 119, 119, 119, 119, 119, 119
Curated region end positions: 260, 260, 260, 260, 260, 260
Curated region terms: molten globule, small molecule binding, molten globule, small molecule binding, molten globule, small molecule binding
Domain/feature annotations: Alphavirus E2 glycoprotein, A domain, Tick-borne Encephalitis virus Glycoprotein, domain 1, Tick-borne Encephalitis virus Glycoprotein, domain 1, Alphavirus E2 glycoprotein, domain B, Alphavirus E2 glycoprotein, domain C, 2.60.40.350, Tick-borne Encephalitis virus Glycoprotein, domain 1, Trypsin-like serine proteases, Trypsin-like serine proteases, Alphavirus E2 glycoprotein, Alphavirus core protein, Alphavirus E3 glycoprotein, Alphavirus E1 glycoprotein
Sequence:
MNYIPTQTFYGRRWRPRPAARPWPLQATPVAPVVPDFQAQQMQQLISAVNALTMRQNAIAPARPPKPKKKKTTKPKPKTQPKKINGKTQQQKKKDKQADKKKKKPGKRERMCMKIENDCIFEVKHEGKVTGYACLVGDKVMKPAHVKGVIDNADLAKLAFKKSSKYDLECAQIPVHMRSDASKYTHEKPEGHYNWHHGAVQYSGGRFTIPTGAGKPGDSGRPIFDNKGRVVAIVLGGANEGSRTALSVVTWNKDMVTRVTPEGSEEWSAPLITAMCVLANATFPCFQPPCVPCCYENNAEATLRMLEDNVDRPGYYDLLQAALTCRNGTRHRRSVSQHFNVYKATRPYIAYCADCGAGHSCHSPVAIEAVRSEATDGMLKIQFSAQIGIDKSDNHDYTKIRYADGHAIENAVRSSLKVATSGDCFVHGTMGHFILAKCPPGEFLQVSIQDTRNAVRACRIQYHHDPQPVGREKFTIRPHYGKEIPCTTYQQTTAETVEEIDMHMPPDTPDRTLLSQQSGNVKITVGGKKVKYNCTCGTGNVGTTNSDMTINTCLIEQCHVSVTDHKKWQFNSPFVPRADEPARKGKVHIPFPLDNITCRVPMAREPTVIHGKREVTLHLHPDHPTLFSYRTLGEDPQYHEEWVTAAVERTIPVPVDGMEYHWGNNDPVRLWSQLTTEGKPHGWPHQIVQYYYGLYPAATVSAVVGMSLLALISIFASCYMLVAARSKCLTPYALTPGAAVPWTLGILCCAPRAHAASVAETMAYLWDQNQALFWLEFAAPVACILIITYCLRNVLCCCKSLSFLVLLSLGATARAYEHSTVMPNVVGFPYKAHIERPGYSPLTLQMQVVETSLEPTLNLEYITCEYKTVVPSPYVKCCGASECSTKEKPDYQCKVYTGVYPFMWGGAYCFCDSENTQLSEAYVDRSDVCRHDHASAYKAHTASLKAKVRVMYGNVNQTVDVYVNGDHAVTIGGTQFIFGPLSSAWTPFDNKIVVYKDEVFNQDFPPYGSGQPGRFGDIQSRTVESNDLYANTALKLARPSPGMVHVPYTQTPSGFKYWLKEKGTALNTKAPFGCQIKTNPVRAMNCAVGNIPVSMNLPDSAFTRIVEAPTIIDLTCTVATCTHSSDFGGVLTLTYKTNKNGDCSVHSHSNVATLQEATAKVKTAGKVTLHFSTASASPSFVVSLCSARATCSASCEPPKDHIVPYAASHSNVVFPDMSGTALSWVQKISGGLGAFAIGAILVLVVVTCIGLRR
Protein: RNA polymerase subunit 13
UniProt accession: B8YB65
Organism: Saccharolobus shibatae B12
Taxonomy: Archaea, Crenarchaeota, Thermoprotei, Sulfolobales, Sulfolobaceae, Saccharolobus
Gene names: rpo13
Length: 104 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 85, 83, 1, 47, 1, 83, 1
Curated region end positions: 32, 104, 104, 104, 52, 32, 104, 104
Curated region terms: disorder, double-stranded DNA binding, disorder, DNA-directed RNA polymerase complex, RNA polymerase binding, disorder, disorder, molten globule
Domain/feature annotations: RNA polymerase Rpo13 subunit HTH domain
Cross-references: PDB:4AYB
Sequence:
MVSGMSTEEEKEGTNDEEVSEEREVEETSEEEFPKLSIQDIELLMKNTEIWDNLLNGKISVDEAKRLFEDNYKDYEKRDSRRKAKKAASKKVKKTKKKEKSVEG
Protein: Cytolethal distending toxin subunit A
UniProt accession: O87120
Organism: Aggregatibacter actinomycetemcomitans
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Pasteurellales, Pasteurellaceae, Aggregatibacter
Gene names: cdtA
Length: 222 residues
Disorder content (fraction disordered): 0.08108108108108109
Dataset labels: Unicellular toxins and antitoxins, Bacterial virulence-related proteins
Curated region start positions: 53
Curated region end positions: 70
Curated region terms: disorder
Domain/feature annotations: 2.80.10.50, Cytolethal distending toxin A/C domain
Cross-references: PDB:2F2F
Sequence:
MKKFLPGLLLMGLVACSSNQRMSDYSQPESQSDLAPKSSTTQFQPQPLLSKASSMPLNLLSSSKNGQVSPSEPSNFMTLMGQNGALLTVWALAKRNWLWAYPNIYSQDFGNIRNWKIEPGKHREYFRFVNQSLGTCIEAYGNGLIHDTCSLDKLAQEFELLPTDSGAVVIKSVSQGRCVTYNPVSPTYYSTVTLSTCDGATEPLRDQTWYLAPPVLEATAVN