Protein: PfEMP1 variant 1 of strain MC
UniProt accession: Q25733
Organism: Plasmodium falciparum
Taxonomy: Eukaryota, Sar, Alveolata, Apicomplexa, Aconoidasida, Haemosporida, Plasmodiidae, Plasmodium, Plasmodium (Laverania)
Gene names: MCvar-1 PfEMP1
Length: 2924 residues
Disorder content (fraction disordered): 0.0047879616963064295
Curated region start positions: 605
Curated region end positions: 618
Curated region terms: disorder
Domain/feature annotations: Duffy-antigen binding domain, Duffy-antigen binding domain, Duffy-antigen binding domain, Duffy-antigen binding domain, 1.20.58.830, 1.20.58.1930, 1.20.58.830, Acidic terminal segments, variant surface antigen of PfEMP1, Acidic terminal segments, variant surface antigen of PfEMP1, PFEMP1 DBL domain, PFEMP1 DBL domain, Duffy binding domain, Duffy binding domain, Duffy binding domain, Duffy binding domain, acidic terminal segments, variant surface antigen of PfEMP1, N-terminal segments of PfEMP1, Cysteine-Rich Interdomain Region 1 gamma, Duffy-binding-like domain, C-terminal subdomain, Duffy-binding-like domain, C-terminal subdomain, Duffy-binding-like domain, C-terminal subdomain
Cross-references: PDB:3C64
Sequence:
MGGGNGGGGTKDKDAKHALDRIGEEVYKEKVENDAEKYKKALKGNLQEAKGIGELASSPNPCKLVEDYYNNRLKRKRYPCANRQTVRFSDEYGGQCTFNRIKDSENNDNSIGACAPYRRLHLCDYNLEKMGKTSTTKHDLLLDVCMAAKYEGDSIKTHYTKHELTNPDTKSQLCTILARSFADIGDIVRGKDLYLGYDDKEKDERKKLENNLIEIFKKIHENLGTQDAKDHYKKDEENYYQLREDWWTANRSTVWKAITCHAGESDKYFRKTCCSGEWTDDKCRCKDEEGKNETNEVPTYFDYVPQYLRWFEEWAEDFCRKRKKKIENAIKNCRGEKGNERYCDLNGYNCEETARGAEIFVKGDDCHKCSVACDRFVKWIDNQRKEFDKQKKKYDEEINKTHGTTITTGNGKINNLYVGHFYKILKKYYPTVDKSLQKLNDEAICKKPPNVGNEKASTVDFNNEVNTTFSHTTYCEACPWCGAQKEKNGGGWKAKEKSCAKKKERIFNKENSTDIKILTPEKGRSKTLEKLKTFCKDGQKIKNDIWKCHYDDNGTDDQTDDSNDCVLGDWGNLTKEDKIMSYNAFFWMWVHDMLIDSIKWRDEHGRCINKDKGKTCIKGCNKKCICFQKWVEQKKTEWGKIKDHFRKQKDIPKDWTHDDFLQTLLMKDLLLEIIQDTYGDANEIKRIEALLEQAGVGGIDFAALAGLYTKGFVAEKDTTIDKLLQHEQKEADKCLKTHTDDTCPPQEDRSVARSESATVPSPPADPKATEEVDANASSDDEDDFEEEEEEEEDEGEEEAEEVQEEKTDESATEAVAPSPPGTTQDGVKPASQEDDVKVCSIVDKALKGKLDDACTLKYGKTAPTSWKCIPSGNNTTTESTTKPGAAGTPSGKDTGSICVPPRRRKLYVGKLHDWAGGETTEAKSQETSGGQKTPSGNESSPSEKLPQGPTPETTKETPESSLLHAFVSPPRLRRFLPWHKFKEQWKAQHGAGATGQQTIIGTLDGGGEETPDKLLKTGHIPPDFLRQMFYTLGDYRDILVGNTDIVVHTSGNKEDMQIMEAIQKKIEQILPTSGSSPSPPRVTQTQHSVENPRKTWWNENGKKIWEGMVCALTYNTDTPSGTAPTQIQEVRTKLRDENSKNPKIPQYKYDQVKLDDTSDAKTTGSPVPSGEKITPLTDFISRPPYFRYLEEWGETFCKERKKRLEKIKEECRGDRTGHEHCSGDGYDCTRTDADRNDKFVDLNCRDCHIQCRKYRKWIDIKFDEYHKQEKKYQGEYDKLTKDKSSGGDNNCCKDIEKHKSAAVFLKELKHCKNGQTSENKGNQEDQLNKLDFDKIPQTFSPSTYCKACPVYGVNCNGNKRGRGGTNGCTTNNEPENKENDKGAASTISILINDGSTNGATNGTTGTTDETLKECSDKYAFFKGLRKQEWTCQKKYGVNQCNLTNRVNDTYFDKDIVFNEFFQRWLRYFVHDYNILKHKIDPCIKKEKQDKTEHKCINGCNIKCECVRKWLEIKGNEWGNIKKHYNINSNDDKETIAYNVKSYFVDQGLFDTDYKKAQKVVEDEKERKKIWGCTGHDECSEKEKEENKNFITNLISELQDKITSCQNKHNPNGKTACDPFPSPTPEETDPLDDDTPDPLDDDQHTEQPKFCPPPPPPMTCVEKIAKELRVEAEGKINNELKGNGKDFNGKCNNVKKKNGAVIGEESCKFEQTYENSVNNINNKCKDNQNERFKIGQKWNFKYIGTIRKDLCIPPRREHMCLDDLSMLGRTTISDSSALLKKIQEAAKSERDDIIRKLLEQNSCDEHRICDAMKYSFADLGDIIRGRDLWNKNSKQKGLQKRLEYAFINIYNKLQNDKNKYEKDRPKYLQLRSDWWDANRKHIWNAMTCNAPDDAKFLKKNPNDTSGSSSSKGIMTTHSNCGYDKEPPDYDYIPQPFRWMQEWSESFCKLLNEEMEQFEKTCGECKKNSITCEDDRNGTNCENCKNQCEKYKKLIHNWKLGFDKYKEIYNEIYNNKDSKINSNEYFKKFLEKLKDKCKELNSSDKCIDEATHCTKYKFSNSENKNHNNYAFKNPPKEYEKACKCDAPDPLDNCPKDSATYEKACNTLLPTKLCESKTFNNDDDSWDTSFVQTSPRDNTGVLVPPRRRQICLKNITTKLRSIEKIDDFKAELMTSAYNEGKLLCELYKKDRDVTLQAMKYSFYDYGDIVKGTDLISTAPLDKLKTKLNVLLKGDGTNEIKEDRGKWWTENRTRVWHAMLCGYKAAGGKIEERDCSLPDDNTHQFLRWFREWSEHFCAKRQKLFNEVKRECASAQCIIEYGTIDPPVCEEACTQYRDYITRKIQEYRLLNYQYNTNFNEKKAEVTKAPEYFNDKCNDKCNCLSKYIDIEKKWKNMYDSFDDNDLKNKCICRQIKPKRPPKKVKPEEEHTPSEQDTPPPLPPKPDDLPPPAEEPFNRDILEKTIPFGIALALGSIAFLFLKKKTKSSVGNLFQILHIPKSDYDIPTKLSPNRYIPYTSGKYRGKRYIYLEGDSGTDSGYTDHYSDITSSSESEYEELDINDIYVPGSPKYKTLIEVVLEPSGNNTTASGKNTPSDTQNDIQNDGIPSSKITDNEWNTLKDEFISNMLQNEPNTEPNMLGYNVDNNTHPTTSRHNVEEKPFIMSIHDRDLYSGEEYSYNVNMVNNDIPISARNGNYSGIDLINDSLNSNKVDIYDELLKRKENELFGTNHTKKNTSTNSVAKNTNTDPIHNQLNLFHTWLDRHRDMCEKWDTNNKKEELLDKLKEEWNKDNNSGNINPSGNTPPTSDIPSGKQSDIPSDNNIHSDIPYVLNTDVSIQIHMDNPKPINEFSNMDTYPNNSSMDTILEDLDKPFNEPYYYDVQDDIYYDVHDHDTSTVDTNAMDEPSKVQIEMDVNTKLVKEKYPIADLWDI