LiteFold/DisProt huggingface dataset:
Protein: Protein Rev
UniProt accession: P69718
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate HXB3)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: rev
Length: 116 residues
Disorder content (fraction disordered): 0.14655172413793102
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 34, 34, 34, 34, 34, 34, 34, 35, 35, 35
Curated region end positions: 50, 50, 50, 50, 50, 50, 50, 50, 46, 46
Curated region terms: disorder, disorder, disorder to order, RNA binding, disorder, disorder to order, RNA binding, protein localization to nucleoplasm, RNA binding, protein binding
Domain/feature annotations: REV protein (anti-repression trans-activator protein)
Sequence:
MAGRSGDSDEDLLKAVRLIKFLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILSTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTILESGAKE
Protein: Myozenin-1
UniProt accession: Q9NP98
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MYOZ, MYOZ1
Length: 299 residues
Disorder content (fraction disordered): 1
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 92, 1, 92, 1, 92, 92, 92, 92, 119, 176, 106, 180, 216, 200, 200, 216, 218, 92
Curated region end positions: 174, 299, 174, 299, 174, 299, 299, 299, 299, 237, 292, 128, 199, 240, 215, 215, 240, 228, 299
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, actinin binding, actinin binding, actinin binding, actinin binding, actinin binding, actinin binding, actinin binding, actinin binding, flexible linker, disorder, actinin binding, actinin binding, molecular condensate scaffold activity
Domain/feature annotations: Calcineurin-binding protein (Calsarcin)
Cross-references: BMRB:50496, BMRB:50497, PDB:7A8T, PDB:7A8U, SASBDB:SASDJJ6, SASBDB:SASDJK6
Sequence:
MPLSGTPAPNKKRKSSKLIMELTGGGQESSGLNLGKKISVPRDVMLEELSLLTNRGSKMFKLRQMRVEKFIYENHPDVFSDSSMDHFQKFLPTVGGQLGTAGQGFSYSKSNGRGGSQAGGSGSAGQYGSDQQHHLGSGSGAGGTGGPAGQAGRGGAAGTAGVGETGSGDQAGGEGKHITVFKTYISPWERAMGVDPQQKMELGIDLLAYGAKAELPKYKSFNRTAMPYGGYEKASKRMTFQMPKFDLGPLLSEPLVLYNQNLSNRPSFNRTPIPWLSSGEPVDYNVDIGIPLDGETEEL
Protein: Protein Vpu
UniProt accession: P19554
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate SF162)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: vpu
Length: 81 residues
Disorder content (fraction disordered): 0.5308641975308642
Dataset labels: Viral proteins
Curated region start positions: 39, 39, 64, 39, 39, 39, 39, 64
Curated region end positions: 81, 51, 78, 48, 48, 81, 51, 78
Curated region terms: disorder, lipid binding, lipid binding, disorder to order, order, disorder, plasma membrane, plasma membrane
Domain/feature annotations: Vpu protein
Cross-references: BMRB:15513, PDB:2K7Y
Sequence:
MQPLQILAIVALVVAAIIAIVVWTIVYIEYRKILRQRKIDRLIDRITERAEDSGNESEGDQEELSALVERGHLAPWDVDDL
Protein: Bis(5'-adenosyl)-triphosphatase
UniProt accession: P49789
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FHIT
Length: 147 residues
Disorder content (fraction disordered): 0.14285714285714285
Dataset labels: NDDs-related proteins, Cancer-related proteins
Curated region start positions: 107, 112, 112
Curated region end positions: 127, 116, 116
Curated region terms: disorder, phosphorylation display site, phosphorylation display site
Domain/feature annotations: HIT domain
Cross-references: PDB:1FHI, PDB:2FHI
Sequence:
MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQTTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKHDKEDFPASWRSEEEMAAEAAALRVYFQ
Protein: Dual specificity phosphatase 29
UniProt accession: Q68J44
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DUPD1, DUSP27, DUSP29
Length: 220 residues
Disorder content (fraction disordered): 0.2
Curated region start positions: 2, 207
Curated region end positions: 31, 220
Curated region terms: disorder, disorder
Domain/feature annotations: Dual specificity phosphatase, catalytic domain
Cross-references: PDB:2Y96
Sequence:
MTSGEVKTSLKNAYSSAKRLSPKMEEEGEEEDYCTPGAFELERLFWKGSPQYTHVNEVWPKLYIGDEATALDRYRLQKAGFTHVLNAAHGRWNVDTGPDYYRDMDIQYHGVEADDLPTFDLSVFFYPAAAFIDRALSDDHSKILVHCVMGRSRSATLVLAYLMIHKDMTLVDAIQQVAKNRCVLPNRGFLKQLRELDKQLVQQRRRSQRQDGEEEDGREL
Protein: Dual specificity protein phosphatase 14
UniProt accession: O95147
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: DUSP14, MKP6
Length: 198 residues
Disorder content (fraction disordered): 0.1111111111111111
Curated region start positions: 2
Curated region end positions: 23
Curated region terms: disorder
Domain/feature annotations: Dual specificity phosphatase, catalytic domain
Cross-references: PDB:2WGP
Sequence:
MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPVIRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKESRHLMPYWGI
Protein: Protein Vpr
UniProt accession: P12520
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate NY5)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: vpr
Length: 96 residues
Disorder content (fraction disordered): 0.17708333333333334
Dataset labels: Viral proteins
Curated region start positions: 1, 1
Curated region end positions: 17, 17
Curated region terms: disorder, protein binding
Domain/feature annotations: VPR/VPX protein
Cross-references: PDB:5JK7
Sequence:
MEQAPEDQGPQREPYNEWTLELLEELKSEAVRHFPRIWLHNLGQHIYETYGDTWAGVEAIIRILQQLLFIHFRIGCRHSRIGVTRQRRARNGASRS
Protein: Protein Tat
UniProt accession: P69697
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BH10)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: tat
Length: 86 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 86, 86, 86, 86, 86, 86, 86
Curated region terms: disorder, pre-molten globule, pre-molten globule, disorder, disorder, disorder to pre-molten globule, metal ion binding
Domain/feature annotations: Transactivating regulatory protein (Tat)
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQSRGDPTGPKE
Protein: RNA-directed RNA polymerase L
UniProt accession: Q05318
Organism: Zaire ebolavirus (strain Mayinga-76)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Ebolavirus
Gene names: L
Length: 2212 residues
Disorder content (fraction disordered): 0.1301989150090416
Dataset labels: Viral proteins
Curated region start positions: 1306, 1306, 1306
Curated region end positions: 1593, 1593, 1593
Curated region terms: disorder, flexible linker, RNA polymerase activity
Domain/feature annotations: Mononegavirales RNA dependent RNA polymerase, Mononegavirales mRNA-capping region V
Sequence:
MATQHTQYPDARLSSPIVLDQCDLVTRACGLYSSYSLNPQLRNCKLPKHIYRLKYDVTVTKFLSDVPVATLPIDFIVPVLLKALSGNGFCPVEPRCQQFLDEIIKYTMQDALFLKYYLKNVGAQEDCVDEHFQEKILSSIQGNEFLHQMFFWYDLAILTRRGRLNRGNSRSTWFVHDDLIDILGYGDYVFWKIPISMLPLNTQGIPHAAMDWYQASVFKEAVQGHTHIVSVSTADVLIMCKDLITCRFNTTLISKIAEIEDPVCSDYPNFKIVSMLYQSGDYLLSILGSDGYKIIKFLEPLCLAKIQLCSKYTERKGRFLTQMHLAVNHTLEEITEMRALKPSQAQKIREFHRTLIRLEMTPQQLCELFSIQKHWGHPVLHSETAIQKVKKHATVLKALRPIVIFETYCVFKYSIAKHYFDSQGSWYSVTSDRNLTPGLNSYIKRNQFPPLPMIKELLWEFYHLDHPPLFSTKIISDLSIFIKDRATAVERTCWDAVFEPNVLGYNPPHKFSTKRVPEQFLEQENFSIENVLSYAQKLEYLLPQYRNFSFSLKEKELNVGRTFGKLPYPTRNVQTLCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGEHATVRGSSFVTDLEKYNLAFRYEFTAPFIEYCNRCYGVKNVFNWMHYTIPQCYMHVSDYYNPPHNLTLENRDNPPEGPSSYRGHMGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVMGDNQCITVLSVFPLETDADEQEQSAEDNAARVAASLAKVTSACGIFLKPDETFVHSGFIYFGKKQYLNGVQLPQSLKTATRMAPLSDAIFDDLQGTLASIGTAFERSISETRHIFPCRITAAFHTFFSVRILQYHHLGFNKGFDLGQLTLGKPLDFGTISLALAVPQVLGGLSFLNPEKCFYRNLGDPVTSGLFQLKTYLRMIEMDDLFLPLIAKNPGNCTAIDFVLNPSGLNVPGSQDLTSFLRQIVRRTITLSAKNKLINTLFHASADFEDEMVCKWLLSSTPVMSRFAADIFSRTPSGKRLQILGYLEGTRTLLASKIINNNTETPVLDRLRKITLQRWSLWFSYLDHCDNILAEALTQITCTVDLAQILREYSWAHILEGRPLIGATLPCMIEQFKVFWLKPYEQCPQCSNAKQPGGKPFVSVAVKKHIVSAWPNASRISWTIGDGIPYIGSRTEDKIGQPAIKPKCPSAALREAIELASRLTWVTQGSSNSDLLIKPFLEARVNLSVQEILQMTPSHYSGNIVHRYNDQYSPHSFMANRMSNSATRLIVSTNTLGEFSGGGQSARDSNIIFQNVINYAVALFDIKFRNTEATDIQYNRAHLHLTKCCTREVPAQYLTYTSTLDLDLTRYRENELIYDSNPLKGGLNCNISFDNPFFQGKRLNIIEDDLIRLPHLSGWELAKTIMQSIISDSNNSSTDPISSGETRSFTTHFLTYPKIGLLYSFGAFVSYYLGNTILRTKKLTLDNFLYYLTTQIHNLPHRSLRILKPTFKHASVMSRLMSIDPHFSIYIGGAAGDRGLSDAARLFLRTSISSFLTFVKEWIINRGTIVPLWIVYPLEGQNPTPVNNFLYQIVELLVHDSSRQQAFKTTISDHVHPHDNLVYTCKSTASNFFHASLAYWRSRHRNSNRKYLARDSSTGSSTNNSDGHIERSQEQTTRDPHDGTERNLVLQMSHEIKRTTIPQENTHQGPSFQSFLSDSACGTANPKLNFDRSRHNVKFQDHNSASKREGHQIISHRLVLPFFTLSQGTRQLTSSNESQTQDEISKYLRQLRSVIDTTVYCRFTGIVSSMHYKLDEVLWEIESFKSAVTLAEGEGAGALLLIQKYQVKTLFFNTLATESSIESEIVSGMTTPRMLLPVMSKFHNDQIEIILNNSASQITDITNPTWFKDQRARLPKQVEVITMDAETTENINRSKLYEAVYKLILHHIDPSVLKAVVLKVFLSDTEGMLWLNDNLAPFFATGYLIKPITSSARSSEWYLCLTNFLSTTRKMPHQNHLSCKQVILTALQLQIQRSPYWLSHLTQYADCELHLSYIRLGFPSLEKVLYHRYNLVDSKRGPLVSITQHLAHLRAEIRELTNDYNQQRQSRTQTYHFIRTAKGRITKLVNDYLKFFLIVQALKHNGTWQAEFKKLPELISVCNRFYHIRDCNCEERFLVQTLYLHRMQDSEVKLIERLTGLLSLFPDGLYRFD
Protein: Envelope glycoprotein
UniProt accession: Q05320
Organism: Zaire ebolavirus (strain Mayinga-76)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Ebolavirus
Gene names: GP
Length: 676 residues
Disorder content (fraction disordered): 0.15680473372781065
Dataset labels: Viral proteins
Curated region start positions: 524, 524, 524, 524, 524, 524, 524, 524, 524, 529, 524, 190, 279, 465, 524, 632
Curated region end positions: 539, 539, 539, 539, 539, 539, 539, 539, 539, 535, 539, 212, 298, 501, 539, 641
Curated region terms: disorder, order, disorder to order, lipid binding, disorder, lipid binding, lipid binding, lipid binding, disorder, lipid binding, viral entry into host cell, disorder, disorder, disorder, viral entry into host cell, disorder
Domain/feature annotations: Filovirus glycoprotein, Envelope glycoprotein GP2-like, HR1-HR2
Cross-references: BMRB:11004, DisProt:DP03538r001, PDB:2RLJ, PDB:3CSY, PDB:5T42
Sequence:
MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFTVVSNGAKNISGQSPARTSSDPGTNTTTEDHKIMASENSSAMVQVHSQGREAAVSHLTTLATISTSPQSLTTKPGPDNSTHNTPVYKLDISEATQVEQHHRRTDNDSTASDTPSATTAAGPPKAENTNTSKSTDFLDPATTTSPQNHSETAGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVDKTLPDQGDNDNWWTGWRQWIPAGIGVTGVIIAVIALFCICKFVF
Protein: Envelope glycoprotein
UniProt accession: P87666
Organism: Zaire ebolavirus (strain Kikwit-95)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Ebolavirus
Gene names: GP
Length: 676 residues
Disorder content (fraction disordered): 0.10207100591715976
Dataset labels: Viral proteins
Curated region start positions: 632, 524, 524, 524, 524, 524, 524, 529, 524, 190, 279
Curated region end positions: 641, 539, 539, 539, 539, 539, 539, 535, 539, 212, 298
Curated region terms: disorder, disorder, disorder, order, disorder, disorder to order, lipid binding, lipid binding, viral entry into host cell, disorder, disorder
Domain/feature annotations: Filovirus glycoprotein, Envelope glycoprotein GP2-like, HR1-HR2
Cross-references: BMRB:11004, DisProt:DP03537r001, DisProt:DP03537r002, DisProt:DP03537r003, DisProt:DP03537r004, DisProt:DP03537r005, DisProt:DP03537r006, DisProt:DP03537r007, DisProt:DP03537r008, DisProt:DP03537r009, DisProt:DP03537r010, DisProt:DP03537r011, DisProt:DP03537r012, DisProt:DP03537r013, DisProt:DP03537r015, DisProt:DP03537r016, PDB:2RLJ, PDB:3CSY, PDB:5T42
Sequence:
MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFTAVSNRAKNISGQSPARTSSDPGTNTTTEDHKIMASENSSAMVQVHSQGREAAVSHLTTLATISTSPQPPTTKPGPDNSTHNTPVYKLDISEATQVEQHHRRTDNDSTASDTPPATTAAGPLKAENTNTSKGTDLLDPATTTSPQNHSETAGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRARREAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYTEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVDKTLPDQGDNDNWWTGWRQWIPAGIGVTGVIIAVIALFCICKFVF
Protein: RING finger protein Z
UniProt accession: A0A097F4I8
Organism: Lassa mammarenavirus
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Ellioviricetes, Bunyavirales, Arenaviridae, Mammarenavirus
Gene names: Z
Length: 99 residues
Disorder content (fraction disordered): 0.5050505050505051
Dataset labels: Viral proteins
Curated region start positions: 1, 74
Curated region end positions: 24, 99
Curated region terms: disorder, disorder
Domain/feature annotations: P-11 zinc finger
Cross-references: EMDB:EMD-31178, PDB:7ELA
Sequence:
MGNKQVKAPEARNSPRASLIPDATHLGPQFCKSCWFENKGLVECNNHYLCLNCLTLLLGVSSRCPICKMPLPTRLRPSAAPTAPPAEAGDNTRPPPYSP
Protein: Nucleoprotein
UniProt accession: Q9DQX7
Organism: Lassa mammarenavirus
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Ellioviricetes, Bunyavirales, Arenaviridae, Mammarenavirus
Gene names: N, NP
Length: 569 residues
Disorder content (fraction disordered): 0.0632688927943761
Dataset labels: Viral proteins
Curated region start positions: 147, 339, 339
Curated region end positions: 157, 363, 363
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: Arenavirus nucleocapsid N-terminal domain, Arenavirus nucleocapsid C-terminal domain
Cross-references: PDB:3R3L
Sequence:
MSASKEVKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKQRRDDSDLKRLRDLNQAVNNLVELKSTQQKSVLRVGTLSSDDLLTLAADLEKLKSKVTRTERPLSSGVYMGNLSSQQLDQRRALLNLIGMTNGSQGSQAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDVVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQSMDGILKSILKVKRALGMFVSDTPGERNPYENILYKICLSGDGWPYIASRTSIVGRAWENTVVDLETDGKPQKIGSGNSNKSLQSAGFSAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEVALYQPISGCYIHFFREPTDLKQFKQDAKYSHGIDIADLFAAQPGLTSAVIEALPRNMVITCQGSEDIKKLLESQGRKDIKLIDIALSKIDSRKFENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTLVLRAVLPRDMVFRTSTPRVVL
Protein: Nucleoprotein
UniProt accession: P13699
Organism: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Ellioviricetes, Bunyavirales, Arenaviridae, Mammarenavirus
Gene names: N
Length: 569 residues
Disorder content (fraction disordered): 0.0632688927943761
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 147, 339, 339
Curated region end positions: 157, 363, 363
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: Arenavirus nucleocapsid N-terminal domain, Arenavirus nucleocapsid C-terminal domain
Cross-references: PDB:3MWP, PDB:3MWT, PDB:3MX2, PDB:3MX5
Sequence:
MSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNNSSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPRVVL
Protein: Protein Vpr
UniProt accession: Q72500
Organism: Human immunodeficiency virus 1
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: vpr
Length: 96 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 96, 96, 96, 96, 96, 96
Curated region terms: disorder, disorder, symbiont-mediated perturbation of host cell cycle progression, viral penetration into host nucleus, release from viral latency, viral genome replication
Domain/feature annotations: VPR/VPX protein
Sequence:
MEQAPEDQGPQREPYNEWTLELLEELKSEAVRHFPRIWLHNLGRHIYETYGDTWAGVEAIIRILQQLPFIHFRIGCRHSRIGVTRQRRARNGASRS
Protein: Pre-glycoprotein polyprotein GP complex
UniProt accession: P08669
Organism: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Ellioviricetes, Bunyavirales, Arenaviridae, Mammarenavirus
Gene names: GP-C, GPC
Length: 491 residues
Disorder content (fraction disordered): 0.11812627291242364
Dataset labels: Viral proteins
Curated region start positions: 1
Curated region end positions: 58
Curated region terms: disorder
Domain/feature annotations: Arenavirus glycoprotein
Cross-references: PDB:5VK2
Sequence:
MGQIVTFFQEVPHVIEEVMNIVLIALSVLAVLKGLYNFATCGLVGLVTFLLLCGRSCTTSLYKGVYELQTLELNMETLNMTMPLSCTKNNSHHYIMVGNETGLELTLTNTSIINHKFCNLSDAHKKNLYDHALMSIISTFHLSIPNFNQYEAMSCDFNGGKISVQYNLSHSYAGDAANHCGTVANGVLQTFMRMAWGGSYIALDSGRGNWDCIMTSYQYLIIQNTTWEDHCQFSRPSPIGYLGLLSQRTRDIYISRRLLGTFTWTLSDSEGKDTPGGYCLTRWMLIEAELKCFGNTAVAKCNEKHDEEFCDMLRLFDFNKQAIQRLKAEAQMSIQLINKAVNALINDQLIMKNHLRDIMGIPYCNYSKYWYLNHTTTGRTSLPKCWLVSNGSYLNETHFSDDIEQQADNMITEMLQKEYMERQGKTPLGLVDLFVFSTSFYLISIFLHLVKIPTHRHIVGKSCPKPHRLNHMGICSCGLYKQPGVPVKWKR
Protein: Membrane-associated protein VP24
UniProt accession: P35256
Organism: Lake Victoria marburgvirus (strain Musoke-80)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Marburgvirus
Gene names: VP24
Length: 253 residues
Disorder content (fraction disordered): 0.04743083003952569
Dataset labels: Viral proteins
Curated region start positions: 242
Curated region end positions: 253
Curated region terms: disorder
Domain/feature annotations: Filovirus membrane-associated protein VP24
Cross-references: PDB:4OR8
Sequence:
MAELSTRYNLPANVTENSINLDLNSTARWIKEPSVGGWTVKWGNFVFHIPNTGMTLLHHLKSNFVVPEWQQTRNLFSHLFKNPKSTIIEPFLALRILLGVALKDQELQQSLIPGFRSIVHMLSEWLLLEVTSAIHISPNLLGIYLTSDMFKILMAGVKNFFNKMFTLHVVNDHGKPSSIEIKLTGQQIIITRVNMGFLVEVRRIDIEPCCGETVLSESVVFGLVAEAVLREHSQMEKGQPLNLTQYMNSKIAI
Protein: Matrix protein VP40
UniProt accession: P35260
Organism: Lake Victoria marburgvirus (strain Musoke-80)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Haploviricotina, Monjiviricetes, Mononegavirales, Filoviridae, Marburgvirus
Gene names: VP40
Length: 303 residues
Disorder content (fraction disordered): 0.11551155115511552
Dataset labels: Viral proteins
Curated region start positions: 1
Curated region end positions: 35
Curated region terms: disorder
Domain/feature annotations: Matrix protein VP40
Cross-references: PDB:5B0V
Sequence:
MASSSNYNTYMQYLNPPPYADHGANQLIPADQLSNQQGITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISAYNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFSTNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMKKRGENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
Protein: Nucleoprotein
UniProt accession: P89522
Organism: Crimean-Congo hemorrhagic fever virus (strain Nigeria/IbAr10200/1970)
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Ellioviricetes, Bunyavirales, Nairoviridae, Orthonairovirus
Gene names: N
Length: 482 residues
Disorder content (fraction disordered): 0.022821576763485476
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 183, 183
Curated region end positions: 193, 193
Curated region terms: disorder, flexible linker
Domain/feature annotations: Nucleocapsid N protein
Cross-references: PDB:4AQG
Sequence:
MENKIEVNNKDEMNRWFEEFKKGNGLVDTFTNSYSFCESVPNLDRFVFQMASATDDAQKDSIYASALVEATKFCAPIYECAWVSSTGIVKKGLEWFEKNAGTIKSWDESYTELKVDVPKIEQLTGYQQAALKWRKDIGFRVNANTAALSNKVLAEYKVPGEIVMSVKEMLSDMIRRRNLILNRGGDENPRGPVSHEHVDWCREFVKGKYIMAFNPPWGDINKSGRSGIALVATGLAKLAETEGKGIFDEAKKTVEALNGYLDKHKDEVDRASADSMITNLLKHIAKAQELYKNSSALRAQSAQIDTAFSSYYWLYKAGVTPETFPTVSQFLFELGKQPRGTKKMKKALLSTPMKWGKKLYELFADDSFQQNRIYMHPAVLTAGRISEMGVCFGTIPVANPDDAAQGSGHTKSILNLRTNTETNNPCAKTIVKLFEVQKTGFNIQDMDIVASEHLLHQSLVGKQSPFQNAYNVKGNATSANII
Protein: Eukaryotic peptide chain release factor GTP-binding subunit
UniProt accession: P05453
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: GST1, PNM2, SAL3, SUF12, SUP2, SUP35, YD9395.05, YDR172W
Length: 685 residues
Disorder content (fraction disordered): 0.36496350364963503
Dataset labels: Condensates-related proteins
Curated region start positions: 1
Curated region end positions: 250
Curated region terms: pre-molten globule
Domain/feature annotations: Elongation factor Tu GTP binding domain, Elongation factor Tu domain 2, GTP-eEF1A C-terminal domain-like
Sequence:
MSDSNQGNNQQNYQQYSQNGNQQQGNNRYQGYQAYNAQAQPAGGYYQNYQGYSGYQQGGYQQYNPDAGYQQQYNPQGGYQQYNPQGGYQQQFNPQGGRGNYKNFNYNNNLQGYQAGFQPQSQGMSLNDFQKQQKQAAPKPKKTLKLVSSSGIKLANATKKVGTKPAESDKKEEEKSAETKEPTKEPTKVEEPVKKEEKPVQTEEKTEEKSELPKVEDLKISESTHNTNNANVTSADALIKEQEEEVDDEVVNDMFGGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAKDAGRQGWYLSWVMDTNKEERNDGKTIEVGKAYFETEKRRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQCVSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHVDRHINAPFMLPIAAKMKDLGTIVEGKIESGHIKKGQSTLLMPNKTAVEIQNIYNETENEVDMAMCGEQVKLRIKGVEEEDISPGFVLTSPKNPIKSVTKFVAQIAIVELKSIIAAGFSCVMHVHTAIEEVHIVKLLHKLEKGTNRKSKKPPAFAKKGMKVIAVLETEAPVCVETYQDYPQLGRFTLRDQGTTIAIGKIVKIAE
Protein: RNA-directed RNA polymerase
UniProt accession: P22173
Organism: Infectious pancreatic necrosis virus (strain Jasper)
Taxonomy: Viruses, Riboviria, Orthornavirae, Birnaviridae, Aquabirnavirus
Gene names: VP1
Length: 845 residues
Disorder content (fraction disordered): 0.09822485207100592
Dataset labels: Viral proteins
Curated region start positions: 1, 793, 799, 793, 20, 1
Curated region end positions: 26, 845, 845, 845, 30, 10
Curated region terms: disorder, disorder, disorder, viral genome replication, disorder, disorder
Domain/feature annotations: Birnavirus RNA dependent RNA polymerase (VP1), palm domain, Birnavirus RNA dependent RNA polymerase (VP1), thumb domain, Birnavirus RNA dependent RNA polymerase (VP1), C-terminal
Cross-references: PDB:2YI8, PDB:2YI9, PDB:2YIB, PDB:3ZED
Sequence:
MSDIFNSPQNKASILTALMKSTTGDVEDVLIPKRFRPAKDPLDSPQAAAQFLKDNKYRILRPRAIPTMVELETDAALPRLRQMVEDGKLKDTVSVPEGTTAFYPKYYPFHKPDHDEVGTFGAPDITLLKQLTFFLLENDFPTGPETLRQVREAIATLQYGSGSYSGQLNRLLAMKGVATGRNPNKTPKTVGYTNEQLAKLLEQTLPINTPKHEDPDLRWAPSWLINYTGDLSTDKSYLPHVTIKSSAGLPYIGKTKGDTTAEALVLADSFIRDLGRAATSADPEAGVKKTITDFWYLSCGLLFPKGERYTQVDWDKKTRNIWSAPYPTHLLLSMVSTPVMNESKLNITNTQTPSLYGFSPFHGGMDRIMTIIRDSLDNDEDLVMIYADNIYILQDNTWYSIDLEKGEANCTPQHMQAMMYYLLTRGWTNEDGSPRYNPTWATFAMNVAPSMVVDSSCLLMNLQLKTYGQGSGNAFTFLNNHLMSTIVVAEWVKAGKPNPMTKEFMDLEEKTGINFKIERELKNLRETIVEAVETAPQDGYLADGSDLPPIRPGKAVELDLLGWSAIYSRQMEMFVPVLENERLIASAAYPKGLENKALARKPGAEIAYQIVRYEAIRLVGGWNNPLLETAAKHMSLDKRKRLEVKGIDVTGFLDDWNNMSEFGGDLEGITLSEPLTNQTLVDINTPLDSFDPKARPQTPRSPKKTLDEVTTAITSGTYKDPKSAVWRLLDQRTKLRVSTLRDQALALKPASSSVDNWAEATEELAQQQQLLMKANNLLKSSLTETREALETIQSDKIIAGKSNPEKNPGTAANPVVGYGEFSEKIPLTPTQKKNAKRREKQRRNQ