Protein: Bifunctional hemolysin/adenylate cyclase
UniProt accession: J7QLC0
Organism: Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC 10739 / 18323)
Taxonomy: Bacteria, Proteobacteria, Betaproteobacteria, Burkholderiales, Alcaligenaceae, Bordetella
Gene names: BN118_0468, cya, cyaA
Length: 1706 residues
Disorder content (fraction disordered): 0.4109026963657678
Dataset labels: Unicellular toxins and antitoxins, Bacterial virulence-related proteins
Curated region start positions: 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1006, 1009, 1009, 1529, 1529, 1632, 1632
Curated region end positions: 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1706, 1681, 1681, 1681, 1681, 1706, 1706
Curated region terms: disorder, disorder to order, disorder, disorder to order, disorder, disorder to order, disorder, disorder to order, disorder, disorder to order, calcium ion binding, calcium ion binding, calcium ion binding, calcium ion binding, calcium ion binding, disorder to order, disorder, disorder, disorder to order, toxin activity, host cell surface binding
Domain/feature annotations: Serralysin-like metalloprotease, C-terminal, Serralysin-like metalloprotease, C-terminal, Anthrax toxin, edema factor, central domain, Serralysin-like metalloprotease, C-terminal, Serralysin-like metalloprotease, C-terminal, Serralysin-like metalloprotease, C-terminal, Serralysin-like metalloprotease, C-terminal, 3.30.70.1720, RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), RTX calcium-binding nonapeptide repeat (4 copies), N-terminal domain in RTX protein, Anthrax toxin LF subunit, Haemolysin-type calcium binding protein related domain
Sequence:
MQQSHQAGYANAADRESGIPAAVLDGIKAVAKEKNATLMFRLVNPHSTSLIAEGVATKGLGVHAKSSDWGLQAGYIPVNPNLSKLFGRAPEVIARADNDVNSSLAHGHTAVDLTLSKERLDYLRQAGLVTGMADGVVASNHAGYEQFEFRVKETSDGRYAVQYRRKGGDDFEAVKVIGNAAGIPLTADIDMFAIMPHLSNFRDSARSSVTSGDSVTDYLARTRRAASEATGGLDRERIDLLWKIARAGARSAVGTEARRQFRYDGDMNIGVITDFELEVRNALNRRAHAVGAQDVVQHGTEQNNPFPEADEKIFVVSATGESQMLTRGQLKEYIGQQRGEGYVFYENRAYGVAGKSLFDDGLGAAPGVPSGRSKFSPDVLETVPASPGLRRPSLGAVERQDSGYDSLDGVGSRSFSLGEVSDMAAVEAAELEMTRQVLHAGARQDDAEPGVSGASAHWGQRALQGAQAVAAAQRLVHAIALMTQFGRAGSTNTPQEAASLSAAVFGLGEASSAVAETVSGFFRGSSRWAGGFGVAGGAMALGGGIAAAVGAGMSLTDDAPAGQKAAAGAEIALQLTGGTVELASSIALALAAARGVTSGLQVAGASAGAAAGALAAALSPMEIYGLVQQSHYADQLDKLAQESSAYGYEGDALLAQLYRDKTAAEGAVAGVSAVLSTVGAAVSIAAAASVVGAPVAVVTSLLTGALNGILRGVQQPIIEKLANDYARKIDELGGPQAYFEKNLQARHEQLANSDGLRKMLADLQAGWNASSVIGVQTTEISKSALELAAITGNADNLKSVDVFVDRFVQGERVAGQPVVLDVAAGGIDIASRKGERPALTFITPLAAPGEEQRRRTKTGKSEFTTFVEIVGKQDRWRIRDGAADTTIDLAKVVSQLVDANGVLKHSIKLDVIGGDGDDVVLANASRIHYDGGAGTNTVSYAALGRQDSITVSADGERFNVRKQLNNANVYREGVATQTTAYGKRTENVQYRHVELARVGQLVEVDTLEHVQHIIGGAGNDSITGNAHDNFLAGGSGDDRLDGGAGNDTLVGGEGQNTVIGGAGDDVFLQDLGVWSNQLDGGAGVDTVKYNVHQPSEERLERMGDTGIHADLQKGTVEKWPALNLFSVDHVKNIENLHGSRLNDRIAGDDQDNELWGHDGNDTIRGRGGDDILRGGLGLDTLYGEDGNDIFLQDDETVSDDIDGGAGLDTVDYSAMIHPGRIVAPHEYGFGIEADLSREWVRKASALGVDYYDNVRNVENVIGTSMKDVLIGDAQANTLMGQGGDDTVRGGDGDDLLFGGDGNDMLYGDAGNDTLYGGLGDDTLEGGAGNDWFGQTQAREHDVLRGGDGVDTVDYSQTGAHAGIAAGRIGLGILADLGAGRVDKLGEAGSSAYDTVSGIENVVGTELADRITGDAQANVLRGAGGADVLAGGEGDDVLLGGDGDDQLSGDAGRDRLYGEAGDDWFFQDAANAGNLLDGGDGRDTVDFSGPGRGLDAGAKGVFLSLGKGFASLMDEPETSNVLRNIENAVGSARDDVLIGDAGANVLNGLAGNDVLSGGAGDDVLLGDEGSDLLSGDAGNDDLFGGQGDDTYLFGVGYGHDTIYESGGGHDTIRINAGADQLWFARQGNDLEIRILGTDDALTVHDWYRDADHRVEIIHAANQAVDQAGIEKLVEAMAQYPDPGAAAAAPPAARVPDTLMQSLAVNWR