LiteFold/DisProt huggingface dataset:
Protein: Protein SopB
UniProt accession: P62558
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: B, ECOK12F047, sopB
Length: 323 residues
Disorder content (fraction disordered): 0.1609907120743034
Curated region start positions: 272, 275, 275, 275
Curated region end positions: 323, 323, 323, 323
Curated region terms: disorder, disorder to order, disorder to order, self-assembly
Domain/feature annotations: Centromere-binding protein HTH domain
Cross-references: PDB:3KZ5, PDB:3MKY
Sequence:
MKRAPVIPKHTLNTQPVEDTSLSTPAAPMVDSLIARVGVMARGNAITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQTPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSAYERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSARSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLSSRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP
Protein: Chromobox protein homolog 1
UniProt accession: P83917
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Cbx, Cbx1
Length: 185 residues
Disorder content (fraction disordered): 0.13513513513513514
Curated region start positions: 79, 79
Curated region end positions: 103, 103
Curated region terms: disorder, flexible linker
Domain/feature annotations: Chromo (CHRromatin Organisation MOdifier) domain, Chromo shadow domain
Sequence:
MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN
Protein: Heterochromatin protein 1
UniProt accession: P05205
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG8409, HP1, Su(var)205
Length: 206 residues
Disorder content (fraction disordered): 0.04854368932038835
Dataset labels: Condensates-related proteins
Curated region start positions: 131, 131
Curated region end positions: 140, 140
Curated region terms: disorder, disorder
Domain/feature annotations: Chromo (CHRromatin Organisation MOdifier) domain, Chromo shadow domain
Cross-references: PDB:3P7J
Sequence:
MGKKIDNPESSAKVSDAEEEEEEYAVEKIIDRRVRKGKVEYYLKWKGYPETENTWEPENNLDCQDLIQQYEASRKDEEKSAASKKDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEAEKILGASDNNGRLTFLIQFKGVDQAEMVPSSVANEKIPRMVIHFYEERLSWYSDNED
Protein: Chromatin-associated protein swi6
UniProt accession: P40381
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Taphrinomycotina, Schizosaccharomycetes, Schizosaccharomycetales, Schizosaccharomycetaceae, Schizosaccharomyces
Gene names: SPAC664.01c, SPAC824.10c, swi6
Length: 328 residues
Disorder content (fraction disordered): 0.6067073170731707
Dataset labels: Condensates-related proteins, RNA-binding proteins
Curated region start positions: 1, 140, 140, 140
Curated region end positions: 74, 264, 264, 264
Curated region terms: disorder, disorder, RNA binding, RNA binding
Domain/feature annotations: Chromo (CHRromatin Organisation MOdifier) domain, Chromo shadow domain
Sequence:
MKKGGVRSYRRSSTSKRSVIDDDSEPELPSMTKEAIASHKADSGSSDNEVESDHESKSSSKKLKENAKEEEGGEEEEEDEYVVEKVLKHRMARKGGGYEYLLKWEGYDDPSDNTWSSEADCSGCKQLIEAYWNEHGGRPEPSKRKRTARPKKPEAKEPSPKSRKTDEDKHDKDSNEKIEDVNEKTIKFADKSQEEFNENGPPSGQPNGHIESDNESKSPSQKESNESEDIQIAETPSNVTPKKKPSPEVPKLPDNRELTVKQVENYDSWEDLVSSIDTIERKDDGTLEIYLTWKNGAISHHPSTITNKKCPQKMLQFYESHLTFRENE
Protein: RNA-binding protein 8A
UniProt accession: Q9Y5S9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSPC114, MDS014, RBM8, RBM8A
Length: 174 residues
Disorder content (fraction disordered): 0.08045977011494253
Curated region start positions: 50
Curated region end positions: 63
Curated region terms: disorder
Domain/feature annotations: G3DSA:3.30.70.330, RNA recognition motif
Cross-references: PDB:1P27
Sequence:
MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNIHLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRRGGRRRSRSPDRRRR
Protein: mRNA decay activator protein ZFP36
UniProt accession: P22893
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Nup475, Tis11, Tis11a, Ttp, Zfp36
Length: 319 residues
Disorder content (fraction disordered): 0.109717868338558
Curated region start positions: 129
Curated region end positions: 163
Curated region terms: disorder
Domain/feature annotations: Zinc finger C-x8-C-x5-C-x3-H type (and similar), Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Cross-references: PDB:1M9O
Sequence:
MDLSAIYESLQSMSHDLSSDHGGTESLGGLWNINSDSIPSGVTSRLTGRSTSLVEGRSCGWVPPPPGFAPLAPRPGPELSPSPTSPTATPTTSSRYKTELCRTYSESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPTEDLALPGQPHVLRQSISFSGLPSGRRSSPPPPGFSGPSLSSCSFSPSSSPPPPGDLPLSPSAFSAAPGTPVTRRDPNQACCPSCRRSTTPSTIWGPLGGLARSPSAHSLGSDPDDYASSGSSLGGSDSPVFEAGVFGPPQTPAPPRRLPIFNRISVSE
Protein: Endoribonuclease ZC3H12A
UniProt accession: Q5D1E7
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Mcpip, Mcpip1, Zc3h12a
Length: 596 residues
Disorder content (fraction disordered): 0.0738255033557047
Curated region start positions: 296, 301, 301, 306
Curated region end positions: 339, 326, 326, 322
Curated region terms: disorder, mRNA binding, mRNA binding, zinc ion binding
Domain/feature annotations: Zc3h12a-like Ribonuclease NYN domain, UBA-like domain, Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain
Cross-references: BMRB:25719, PDB:2N5K, PDB:5H9W
Sequence:
MSDPCGTKPVQESNPTMSLWSLEDRHSSQGRPQPDQDPVAKEAPTSELQMKVDFFRKLGYSSSEIHSVLQKLGVQADTNTVLGELVKHGSATERECQALTAPSPQPPLVPRGGSTPKPSTLEPSLPEEDREGSDLRPVVIDGSNVAMSHGNKEVFSCRGILLAVNWFLERGHTDITVFVPSWRKEQPRPDVPITDQHILRELEKKKILVFTPSRRVGGKRVVCYDDRFIVKLAFESDGVVVSNDTYRDLQGERQEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPSLDNFLRKKPLPSEHRKQPCPYGKKCTYGIKCRFFHPERPSRPQRSVADELRANALLSPPRTPVKDKSSQRPSPASQSSSVSLEAEPGSLDGKKLGARSSPGPHREGSPQTCAPAGRSLPVSGGSFGPTEWLAHTQDSLPYTSQECLDSGIGSLESQMSELWGVRGGSPGESGPTRGPYAGYHSYGSKVPAAPSFSPFRPAMGAGHFSVPTDYVPPPPTYPSREYWSEPYPLPPPTPVLQEPQRPSPGAGGGPWGRVGDLAKERAGVYTKLCGVFPPHLVEAVMRRFPQLLDPQQLAAEILSYKSQHLSE
Protein: SH2 domain-containing protein 3C
UniProt accession: Q8N5H7
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NSP3, SH2D3C, UNQ272/PRO309/PRO34088
Length: 860 residues
Disorder content (fraction disordered): 0.01627906976744186
Curated region start positions: 756
Curated region end positions: 769
Curated region terms: disorder
Domain/feature annotations: SH2 domain, Ras guanine-nucleotide exchange factors catalytic domain, SH2 domain, RasGEF domain
Cross-references: PDB:3T6G
Sequence:
MTEGTKKTSKKFKFFKFKGFGSLSNLPRSFTLRRSSASISRQSHLEPDTFEATQDDMVTVPKSPPAYARSSDMYSHMGTMPRPSIKKAQNSQAARQAQEAGPKPNLVPGGVPDPPGLEAAKEVMVKATGPLEDTPAMEPNPSAVEVDPIRKPEVPTGDVEEERPPRDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLRSHAWYHGRIPREVSETLVQRNGDFLIRDSLTSLGDYVLTCRWRNQALHFKINKVVVKAGESYTHIQYLFEQESFDHVPALVRYHVGSRKAVSEQSGAIIYCPVNRTFPLRYLEASYGLGQGSSKPASPVSPSGPKGSHMKRRSVTMTDGLTADKVTRSDGCPTSTSLPRPRDSIRSCALSMDQIPDLHSPMSPISESPSSPAYSTVTRVHAAPAAPSATALPASPVARRSSEPQLCPGSAPKTHGESDKGPHTSPSHTLGKASPSPSLSSYSDPDSGHYCQLQPPVRGSREWAATETSSQQARSYGERLKELSENGAPEGDWGKTFTVPIVEVTSSFNPATFQSLLIPRDNRPLEVGLLRKVKELLAEVDARTLARHVTKVDCLVARILGVTKEMQTLMGVRWGMELLTLPHGRQLRLDLLERFHTMSIMLAVDILGCTGSAEERAALLHKTIQLAAELRGTMGNMFSFAAVMGALDMAQISRLEQTWVTLRQRHTEGAILYEKKLKPFLKSLNEGKEGPPLSNTTFPHVLPLITLLECDSAPPEGPEPWGSTEHGVEVVLAHLEAARTVAHHGGLYHTNAEVKLQGFQARPELLEVFSTEFQMRLLWGSQGASSSQARRYEKFDKVLTALSHKLEPAVRSSEL
Protein: Docking protein 1
UniProt accession: P97465
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Dok, Dok1
Length: 482 residues
Disorder content (fraction disordered): 0.02074688796680498
Curated region start positions: 257
Curated region end positions: 266
Curated region terms: disorder
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), PH domain, PTB domain (IRS-1 type)
Cross-references: PDB:1P5T, PDB:1UEF
Sequence:
MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSRGGRGGSRRLDCKMIRLAECVSVVPVTVESPPEPGAVAFRLDTAQRSHLLAADAVSSTAWVQTLCRTAFPKGGWALAQTENQPKFSALEMLENSLYSPTWEGSQFWVTSQKTEASERCGLQGSYILRVEAEKLTLLTLGAQSQILEPLLFWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTSQGNDIFQAVEAAIQQQKAQGKVGQAQDILRTDSHDGETEGKTVPPPVPQDPLGSPPALYAEPLDSLRIPPGPSQDSVYSDPLGSTPAGAGEGVHSKKPLYWDLYGHVQQQLLKTKLTDSKEDPIYDEPEGLAPAPPRGLYDLPQEPRDAWWCQARLKEEGYELPYNPATDDYAVPPPRSPKPAPAPKPQGLILPESGTTRGSGSKGFSSDTALYSQVQKSGTSGAWDCGLSKVGNDRAGVKSEGST
Protein: Lamina-associated polypeptide 2, isoforms alpha/zeta
UniProt accession: Q61033
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Lap2, Tmpo
Length: 693 residues
Disorder content (fraction disordered): 0.11544011544011544
Curated region start positions: 472, 51, 51
Curated region end positions: 491, 110, 110
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: G3DSA:1.10.720.40, G3DSA:1.10.720.40, LEM domain, Thymopoietin protein, Lamina-associated polypeptide 2 alpha
Cross-references: PDB:2V0X
Sequence:
MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEEREPTPVLGSGASVGRGRGAVGRKATKKTDKPRLEDKDDLDVTELSNEELLDQLVRYGVNPGPIVGTTRKLYEKKLLKLREQGTESRSSTPLPTVSSSAENTRQNGSNDSDRYSDNDEGKKKEHKKVKSARDCVPFSELASTPSGAFFQGISFPEISTRPPLGRTELQAAKKVQTTKRDPPRETCTDTALPGKGQTHKLAPGRSLFIPSESSYDRCVEKSSSPSSQREFAARLVSAAASPSLIRETTTTYSKDIVENICRGGKSRAQPLRAEEPGVSDQSVFSSEREVLQESERSQVISPPLAQAIRDYVNSLLVQGGVGSLPGTSDSVPTLDVENICKRLSQSSYQDSESLSPPRKVPRLSEKPARGGDSGSCVAFQNTPGSEHRSSFAKSVVSHSLTTLGVEVSKPPPQHDKIEASEPSFPLHESILKVVEEEWQQIDRQLPSVACRYPVSSIEAARILSVPKVDDEILGFISEATPRAATQASSTESCDKHLDLALCRSYEAAASALQIAAHTAFVAKSLQADISQAAQIINSDPSDAQQALRILNRTYDAASYLCDAAFDEVRMSACAMGSSTMGRRYLWLKDCKISPASKNKLTVAPFKGGTLFGGEVHKVIKKRGNKQ
Protein: FAD-linked sulfhydryl oxidase ALR
UniProt accession: P55789
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ALR, GFER, HERV1, HPO
Length: 205 residues
Disorder content (fraction disordered): 0.06341463414634146
Dataset labels: NDDs-related proteins
Curated region start positions: 81
Curated region end positions: 93
Curated region terms: disorder
Domain/feature annotations: ERV/ALR sulfhydryl oxidase domain, Erv1 / Alr family
Cross-references: PDB:3MBG
Sequence:
MAAPGERGRFHGGNLFFLPGGARSEMMDDLATDARGRGAGRRDAAASASTPAQAPTSDSPVAEDASRRRPCRACVDFKTWMRTQQKRDTKFREDCPPDREELGRHSWAVLHTLAAYYPDLPTPEQQQDMAQFIHLFSKFYPCEECAEDLRKRLCRNHPDTRTRACFTQWLCHLHNEVNRKLGKPDFDCSKVDERWRDGWKDGSCD
Protein: Stability determinant
UniProt accession: Q8XAD5
Organism: Escherichia coli O157:H7
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: ECs_2280
Length: 63 residues
Disorder content (fraction disordered): 1
Dataset labels: Unicellular toxins and antitoxins
Curated region start positions: 1, 1, 1, 1, 29, 15, 15, 42, 42, 5, 1, 1, 29
Curated region end positions: 63, 63, 63, 63, 41, 34, 34, 61, 61, 49, 12, 15, 41
Curated region terms: disorder, disorder, disorder, disorder, flexible linker, protein binding, molecular function regulator, molecular function regulator, protein binding, disorder to order, molecular adaptor activity, disorder, disorder
Domain/feature annotations: Stability determinant
Cross-references: PDB:3ZBE, PDB:5CW7, PDB:5CZF
Sequence:
MNRALSPMVSEFETIEQENSYNEWLRAKVATSLADPRPAIPHDEVERRMAERFAKMRKERSKQ
Protein: Spike glycoprotein
UniProt accession: P59594
Organism: Human SARS coronavirus
Taxonomy: Viruses, Riboviria, Orthornavirae, Pisuviricota, Pisoniviricetes, Nidovirales, Cornidovirineae, Coronaviridae, Orthocoronavirinae, Betacoronavirus, Sarbecovirus
Gene names: 2, S
Length: 1255 residues
Disorder content (fraction disordered): 0.15219123505976095
Dataset labels: Viral proteins
Curated region start positions: 1, 661, 812, 1120, 661, 661, 661, 1059, 810, 1105
Curated region end positions: 17, 673, 831, 1196, 673, 673, 674, 1196, 830, 1193
Curated region terms: disorder, disorder, disorder, disorder, limited proteolysis display site, limited proteolysis display site, disorder, disorder, disorder, disorder
Domain/feature annotations: Single helix bin, Coronavirus spike glycoprotein S2, Betacoronavirus spike glycoprotein S1, receptor binding, Betacoronavirus-like spike glycoprotein S1, N-terminal
Cross-references: PDB:5WRG, PDB:5X58, PDB:5X5B, PDB:6ACC, PDB:6ACD
Sequence:
MFIFLLFLTLTSGSDLDRCTTFDDVQAPNYTQHTSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTINHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTMNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGTQTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLREFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAILTAFSPAQDIWGTSAAAYFVGYLKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYWPLNDYGFYTTTGIGYQPYRVVVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGICASYHTVSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT
Protein: Spike glycoprotein
UniProt accession: K9N5Q8
Organism: Middle East respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
Taxonomy: Viruses, Riboviria, Orthornavirae, Pisuviricota, Pisoniviricetes, Nidovirales, Cornidovirineae, Coronaviridae, Orthocoronavirinae, Betacoronavirus, Merbecovirus
Gene names: 3, S
Length: 1353 residues
Disorder content (fraction disordered): 0.11751662971175168
Dataset labels: Viral proteins
Curated region start positions: 699, 745, 1207, 367, 427, 579, 366, 367, 591
Curated region end positions: 709, 756, 1294, 379, 437, 589, 380, 380, 601
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Single helix bin, Coronavirus spike glycoprotein S2, Betacoronavirus spike glycoprotein S1, receptor binding, Betacoronavirus-like spike glycoprotein S1, N-terminal, Coronavirus spike glycoprotein S2, intravirion
Cross-references: PDB:4XAK, PDB:5GMQ, PDB:5X59, PDB:5X5C, PDB:5X5F, PDB:6C6Z
Sequence:
MIHSVFLLMFLLTPTESYVDVGPDSVKSACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYVYSAGHATGTTPQKLFVANYSQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYCILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYTYNITEDEILEWFGITQTAQGVHLFSSRYVDLYGGNMFQFATLPVYDTIKYYSIIPHSIRSIQSDRKAWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEGVECDFSPLLSGTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCSRFLSDDRTEVPQLVNANQYSPCVSIVPSTVWEDGDYYRKQLSPLEGGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQRFVYDAYQNLVGYYSDDGNYYCLRACVSVPVSVIYDKETKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDTPSTLTPRSVRSVPGEMRLASIAFNHPIQVDQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFHKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTKYVAPQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYTYYNKWPWYIWLGFIAGLVALALCVFFILCCTGCGTNCMGKLKCNRCCDRYEEYDLEPHKVHVH
Protein: ATP-binding cassette sub-family C member 8
UniProt accession: Q09428
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ABCC8, HRINS, SUR, SUR1
Length: 1581 residues
Disorder content (fraction disordered): 0.03542061986084757
Curated region start positions: 621, 621
Curated region end positions: 676, 676
Curated region terms: disorder, flexible linker
Domain/feature annotations: ABC transporter type 1, transmembrane domain, ABC transporter type 1, transmembrane domain, ABC transporter, ABC transporter, ABC transporter transmembrane region, ABC transporter transmembrane region
Cross-references: PDB:6C3O, PDB:6C3P
Sequence:
MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDGVTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFPKLLIALLVYWTLAFITKTIKFVKFLDHAIGFSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFSPSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVPLRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFWSSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRDGLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAGILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTPAARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK
Protein: TOG array regulator of axonemal microtubules protein 1
UniProt accession: Q6A070
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Fam179b, Kiaa0423, Togaram1
Length: 1776 residues
Disorder content (fraction disordered): 0.01463963963963964
Curated region start positions: 595
Curated region end positions: 620
Curated region terms: disorder
Domain/feature annotations: Leucine-rich Repeat Variant, Leucine-rich Repeat Variant, Leucine-rich Repeat Variant, Leucine-rich Repeat Variant, Centrosomal protein CEP104-like, TOG domain
Cross-references: PDB:5DN7
Sequence:
MAAAPSELLPLPPPATPGSYRLLSRCRPYAPGTDGRRSGGTMRGEKNYYCRGAAGDHGSCPATPSPLASTLLLPAEAVSTSWSGPGSGLSGGDEEETRLLQLLRTAPDPSEAFQALQAALPRRGGRLGFPRRKEALYRALGRVLVEGGSEEKRLCLQLLSDVLRGQGEAGQLEEAFSLALLPQLVVSLREDNPALRKDALQILHICLRRSSGQVLRTLIQGLESPDARLRASTALLLPILFTPEDLLQGLDLTEVIISLARKLGDQEMEEESETAFSSLQQIGERLGQERFHSYISRLPSALRRHYNRRLESQYGSQVPYYLELEASGFSEDAAPCVVNLSSSNLKFEIIPQELHARLLDQEDYKNRTQAVEELKQLLGKFNPSSTPHASLVGFISLLYNLLDDSNFKVVHGTLQVLHLLVIRLGEQVQQFLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVGPQRVLSLLLENLKHKHSRVREEVVNICICSLLTYPSEDFDLPKLSFDLAPALVDSKRRVRQAALEAFAVLASSMGSGKTNVLFKAVDTVELQDNGDGVMNAVQARLARKTLPRLTEQGFVEYAILMPSSAQGRSSHLAHGADTDWLMSGNRTQSAHCYCGDHTRDSMQLYGSYSPTICTRRVLSAGKGKNKLPWENEQPGVMGENQTSNSKDIKDTEQFSAHDLIPSPKLKPSQGMPASDDLCFSKKRSSRNLFQSSRDFNSESVPTCGAGNTADLQTNLPGKCGQLGLSQIGCRTGSVGSDLQFLGTANGHQDKVYASIDFGSKTQQTFGSQSERTSSYSGSNASPGSFILPSYPLASPRTSPKHTSPLSVAPKKSQDNSISFSNSWPLKSFEGLSKPSPQKKLANQKSSDPTGENFQEKTTAVQLTPALVRSPSSRRGLNGTKPVPPIPRGINLLPDKADLSTMGHMKKQPDDIWKSEKDNLTIDLSELNFRDKDLDQEEMHSSLRSLRNSAAKKRAKLSGSSSTSDVDSPDSAMKLELTIDSPSRASSPNISSYSESGVYSQESLTSSLSTTPQGKRIMSDIFPTFGSKPCSTRLSSAKKTSHAAEQSPSAGFTRSSNLQQISSFDFTSTNTLSEDSVVIVGKGVFGNPNSAPTTCSQPVISSVESEDTFPVKPSIEPPSGVYGRAVQHNAPLYPEVENDKDTKVSIAKSTYEKMRQKRKEEKELLDAKDCERKETNPWERIKHLGSEKMTSENEPSSGVIPQYKERMSSVTHSPEIMDSLELRPFSKPDIALTEALRLLADEDWEKKMEGLNFVRCLAAFHSDLLNTKLHETTFAVVQEVKNLRSGVSRAAVVCLGDLFTYLKKSMDQELDSAVRALLHKAGESNTFIREDVDKALKAMVNNVTPARAVTSLINGGQSHLHIAVRRCTAQHLADVVECMDPERISSGTKDMADRLLPAAAKFAQDSSQETRYYGRKMLFLMMGHPNFEKLLEKYIPSKDLPYIKESVKNLRLKGLGEIPLDTASAKGRRSHPGSVGNTRSSSVSRDAFSSSEREVTEVREVPRKSAPRNSLESAEYIKVITGLLNAKDFRDRINGIKQLLSDTENNQELVVGNIVKIFDAFKSRLHDSNSKVNLVALETMHKMIPLLRDNLSPIINMLIPAIVDNNLNSKNPGIYAAATNVVHALSQHVDNYLLLQPFCTKAQFLNGKAKQDMTEKLADIVTELYQRKPHATEQKVLVVLWHLLGNMTHSGSLPGAGGNIRTATAKLSKALFTQMGQNLLNQAASQPPHIKKSLEELLDVTVLSEL
Protein: D-glucuronyl C5-epimerase B
UniProt accession: F1QR43
Organism: Danio rerio
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Actinopterygii, Neopterygii, Teleostei, Ostariophysi, Cypriniformes, Danionidae, Danioninae, Danio
Gene names: glceb
Length: 586 residues
Disorder content (fraction disordered): 0.03754266211604096
Curated region start positions: 51
Curated region end positions: 72
Curated region terms: disorder
Domain/feature annotations: D-glucuronyl C5-epimerase C-terminus, D-glucuronyl C5-epimerase, beta-sandwich domain
Cross-references: PDB:4PW2, PDB:4PXQ
Sequence:
MMRCLAARVHYKTLIVICALLSLLTVLLWNKCTSEKALRFLPRHPQPPPSPKIDSHPQQPQPPEPPPVVGGVRYEEIDCLINDDATIKGRREGSEVYMPFSWMEKYFEVYGKVVQYDGYDRFEFSHSYSKVYAQREQYHPNGVFMSFEGYNVEVRDRVKCISGVEGVPLSTQWGPQGYFYAIQIAQYGLSHYSKNLTERPPHVEVYDTAEERDSRSSAWTVPKGCSLTRVYDKTRATSVRQFSAPENSEGVSLPLGNTKDFIISFDLKFTSNGSVSVILETTEKGPPFVIHYVTTTQLILLKDRDITYGIGPRTTWTTVTRDLLTDLRKGIGLSNTKAVKATKTMPRRVVKLVVHGTGTIDNITISTTSHMAAFYAASDWLVRNQDERGGWPIMVTRKLGEGFRALEPGWYSAMAQGQAMSTLVRAYLMTKDDTYLKAALRATGPFKLPSEQHGVKAVFMNKYDWYEEYPTIPSSFVLNGFIYSLIGLFDLAQTAGEKLGRDAGQLYSKGMESLKVMLPLYDTGSGTIYDLRHFILGTAPNLARWDYHTTHINQLQLLGTIDNSPIFRDSVKRWKSYLKGGRAKHN
Protein: Prostacyclin synthase
UniProt accession: F1RE08
Organism: Danio rerio
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Actinopterygii, Neopterygii, Teleostei, Ostariophysi, Cypriniformes, Danionidae, Danioninae, Danio
Gene names: ptgis, ptgisl
Length: 480 residues
Disorder content (fraction disordered): 0.05
Curated region start positions: 305, 232
Curated region end positions: 316, 243
Curated region terms: disorder, disorder
Domain/feature annotations: Cytochrome P450, Cytochrome P450
Cross-references: PDB:3B98, PDB:3B99
Sequence:
MMWTALLLVGLSILVIVLYGRRTRRRNEPPLDKGMIPWLGHALEFGKDAAKFLTRMKEKHGDIFTVRAAGLYITVLLDSNCYDAVLSDVASLDQTSYAQVLMKRIFNMILPSHNPESEKKRAEMHFQGASLTQLSNSMQNNLRLLMTPSEMGLKTSEWKKDGLFNLCYSLLFKTGYLTVFGAENNDSAALTQIYEEFRRFDKLLPKLARTTINKEEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYVKQLQDEGIDAEMQRRAMLLQLWVTQGNAGPAAFWVMGYLLTHPEALRAVREEIQGGKHLRLEERQKNTPVFDSVLWETLRLTAAALITRDVTQDKKIRLSNGQEYHLRRGDRLCVFPFISPQMDPQIHQQPEMFQFDRFLNADRTEKKDFFKNGARVKYPSVPWGTEDNLCPGRHFAVHAIKELVFTILTRFDVELCDKNATVPLVDPSRYGFGILQPAGDLEIRYRIRF