LiteFold/DisProt huggingface dataset:
Protein: Proteasome subunit beta
UniProt accession: A4HV47
Organism: Leishmania infantum
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LINJ.12.0003
Length: 283 residues
Disorder content (fraction disordered): 0.19081272084805653
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 54
Curated region terms: disorder
Domain/feature annotations: Proteasome subunit
Cross-references: PDB:6QM7, PDB:6QM8
Sequence:
MLQRPDHTLLQDPSYPKDIEQKLTENGPAQAGKQLFQPDLAVIDPQLSEAVSLGTTILAVSYKGGVVLAADSRTSSGTYVVNRASNKLTKLTEKIYCCRSGSAADTQALAERVSNYLGSYQTDIGADVNVATAANLFHKMCYVNRWNISAGIIVAGYDPINGGSVYSIPSGGSCVKLDYALGGSGSIFLYSFFDANYKPGMSKGECVAFCQRAVAHAYSRDGSSGGLIRTITLDAEEAEDLTVPWKRSPYCMEKDPKYQVQAVQNPPFSSSAKVTGNRMSSTG
Protein: Proteasome subunit beta
UniProt accession: A4IDD6
Organism: Leishmania infantum
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LINJ_36_1730
Length: 302 residues
Disorder content (fraction disordered): 0.32781456953642385
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1, 1
Curated region end positions: 99, 99
Curated region terms: disorder, disorder
Domain/feature annotations: Proteasome subunit
Cross-references: EMDB:10462, PDB:6QM7, PDB:6QM8, PDB:6TCZ
Sequence:
MFADFESVMSSNFTLDDCPRVGPFTYHNMDEDTLEEPLSLCSYRRAPQQTTERSPASCDAVTADPLDSSRYLHGENRCWTLTASCPVPRAIPKIDMKKGTTTLAFRFNGGIIVAVDSRASTGQYIASQTVLKVLEINDYLLGTLAGGAADCQYWERVLGMECRLWELRNGSRITVAAASKILANITYAYRNHGLSMGTMLAGWDQFGPSLYYVDDKGSRVKQDLFSVGSGSIYAYGVLDTGYRKDLSVEDACDLARRSIFHATYRDGASGGIVTVYHVHEKGWTKISRDDQTKLYDRYFPSQ
Protein: Proteasome subunit beta
UniProt accession: A4IBS2
Organism: Leishmania infantum
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LINJ_35_3880
Length: 254 residues
Disorder content (fraction disordered): 0.1141732283464567
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1, 1
Curated region end positions: 29, 29
Curated region terms: disorder, disorder
Domain/feature annotations: Proteasome subunit
Cross-references: EMDB:10462, PDB:6QM8, PDB:6TCZ
Sequence:
MPGFNFENVQRNLSLENEGYSAPRTLKTGTTIVGVVYKDGVVLGADTRATEGSIVADKCCRKIHYMAPNIMCCGAGTSADTEAVTNMVSSHLALHRLETGKQSRVLEALTLLKRHLYRYQGHVSAALVLGGVDVEGPFLATIAPHGSTDRLPFVTMGSGSIAAMAQLEVAYKDNMTCEEAKELVTSAIHKGIFNDPYSGTQVDVCVITKDKTELMIGYDTPNKRMHPRQEVMLPPGTTPVLKEEIRHLVDIVDV
Protein: DNA topoisomerase I-like protein
UniProt accession: Q8WQM6
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Length: 262 residues
Disorder content (fraction disordered): 0.03816793893129771
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 201
Curated region end positions: 210
Curated region terms: disorder
Domain/feature annotations: C-terminal topoisomerase domain
Cross-references: PDB:2B9S
Sequence:
MQPVQSPPVAPPSVPVAAPKKTPIDISALKLKMSPSVRATLAAAGVLGQCPRPIEAADEDALLKLKPMKTMVPSVKKVVAPVATTAPPPKVRRVESSSSSSSDSSSSSSDDDSSTDDSSGSDSSSYSSDDRSSSSAESVVSGEATLFHIAQSQGLVNKEVLTQEEEEVPTLVPPRPPVVRSFPNDIGKALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPINKIFSATIQKKFPWAMNAENFDF
Protein: Glycylpeptide N-tetradecanoyltransferase
UniProt accession: D0AB09
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: nmt
Length: 421 residues
Disorder content (fraction disordered): 0.023752969121140145
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 10
Curated region terms: disorder
Domain/feature annotations: Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain, Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
Cross-references: PDB:2WUU
Sequence:
MSRNPSNSDAAHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPSYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGQEEEAAKYDAPRHICEINFLCVHKQLREKRLAPILIKEVTRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPNAPKNSGLREMKPSDVPQVRRILMNYLDNFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNILNAAYVHYYAATSMPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML
Protein: Proteasome subunit beta
UniProt accession: A0A504X6A3
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: CGC20_24015, CGC21_10040, LDHU3_12.0050
Length: 283 residues
Disorder content (fraction disordered): 0.19081272084805653
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 54
Curated region terms: disorder
Domain/feature annotations: Proteasome subunit
Cross-references: EMDB:10462, PDB:6TCZ
Sequence:
MLQRPDHTLLQDPSYPKDIEQKLTENGPAQAGKQLFQPDLAVIDPQLSEAVSLGTTILAVSYKGGVVLAADSRTSSGTYVVNRASNKLTKLTEKIYCCRSGSAADTQALAERVSNYLGSYQTDIGADVNVATAANLFHKMCYVNRWNISAGIIVAGYDPINGGSVYSIPSGGSCVKLDYALGGSGSIFLYSFFDANYKPGMSKSECVAFCQRAVAHAYSRDGSSGGLIRTITLDAEEAEDLTVPWKRSPYCMEKDPKYQVQAVQNPPFSSSAKVTGNRMSSTG
Protein: Proteasome subunit beta
UniProt accession: A0A3S7WPD8
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: CGC20_20280, CGC21_24485, LDHU3_06.0180, LdCL_060006300
Length: 247 residues
Disorder content (fraction disordered): 0.13360323886639677
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 33
Curated region terms: disorder
Domain/feature annotations: Proteasome subunit
Cross-references: EMDB:10462, PDB:6TCZ, PDB:6TD5
Sequence:
MIEDHAEYGHNHYPQKLASSTLTLPKQGAKQQQWSPYQDNGGTTAAIAGKDFVILAGDTRLNGDYCLHSRHDQSKIFQLTPYTYMASNGMQADRLQLQQMLKYRVKWYQYNNGGRVPPTKAIAQLMSTMLYHRRFFPYYTFNMVVGLDEEGHGVCYSYDAVGSTEPFLYGTRGSAASFLEPVLDCLINRQHMTAQAPPEMTKEETLAMLKNAFTGAAERDIYTGDSVSFFIITKDGVQRESFELRKD
Protein: 40S ribosomal protein S11, putative
UniProt accession: Q9TXA6
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LDHU3_20.1990, LDHU3_21.2120, LdCL_200021000, LdCL_210023700
Length: 141 residues
Disorder content (fraction disordered): 0.09219858156028368
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 129
Curated region end positions: 141
Curated region terms: disorder
Domain/feature annotations: Ribosomal protein S17, Ribosomal_S17 N-terminal
Cross-references: EMDB:7024, PDB:6AZ1
Sequence:
MHRPSRKHVNKSGHIRYSKKIGLGFKTPAKALNGKYIDRKCPFTSNVVIRGRILRGVVHSTKMHRTIIIRRNYLHFIKKYQRYQKRHKSLAVHCSPAFDPKQGDEVVIGQCRPLSKTIRYNVLEVVSKSSADKMGKKFAKN
Protein: 40S ribosomal protein S6
UniProt accession: O44012
Organism: Leishmania infantum
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: RPS6, RS6
Length: 249 residues
Disorder content (fraction disordered): 0.04417670682730924
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 239
Curated region end positions: 249
Curated region terms: disorder
Domain/feature annotations: Ribosomal protein S6e
Cross-references: EMDB:7024, PDB:6AZ1
Sequence:
MYLNIAYPRNGTVKQFEISDEVLRRVQLQDYRLGNEVDGAIFGSEFKGYIFRLRGGSDKDGFPMVPGVLASSRVSLLVKRGAIGFNTFRGYQGERRRKNVRGCVLASDIALVNVTISKVGDQPIEGVTDTTAPRRLGPKRASKIRKLFNLSRTEDVRKYVVRRRVVKSGKKDRLKAPKIQRLITPRVKARRAKKAKDAIAKVRASAAERREYLRLIASNRRALRQRDHSKKHTQKVHAQRAEVAAFQKK
Protein: 60S ribosomal protein L23a
UniProt accession: D1M863
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Length: 145 residues
Disorder content (fraction disordered): 0.1724137931034483
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 25
Curated region terms: disorder
Domain/feature annotations: Ribosomal protein L23
Cross-references: EMDB:8343, PDB:5T2A
Sequence:
MPPAQKTVKKAAPKDAKATKVVKVSTRKAYTRPQFRRPHTYRKPATAKPSNRVTVESKDIAAFNVIRYPLTTDKAMKKIEENNTLTFIVDARANKTEIKKAIRKLYQVKAVKVNTLIRPDGLKKAYIRLSAAHDALDTANKIGLV
Protein: Pteridine reductase
UniProt accession: Q6QDB5
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Length: 288 residues
Disorder content (fraction disordered): 0.20833333333333337
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 70, 112, 227
Curated region end positions: 80, 132, 254
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: short chain dehydrogenase, Enoyl-(Acyl carrier protein) reductase
Cross-references: PDB:2XOX
Sequence:
MTAPTVPVALVTGAAKRLGSGIAEGLHAEGYAVCLHYHRSAAEANTLAATLNARRPNSAITVQADLSNVAKAPAGGADGAAPVTLFKRCADLVAACYTHWGRCDVLVNNASSFYPTPLLRKDEDGHVPCVGDREAMEAAAADLFGSNAMAPYFLIKAFAHRVADTPAEQRGTNYSIVNMVDAMTSQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLADDMPPAVREDYRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYVTGTCVKVDGGYSLTRA
Protein: Proliferating cell nuclear antigen
UniProt accession: B5TV91
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: PCNA
Length: 292 residues
Disorder content (fraction disordered): 0.19863013698630136
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 186, 118, 118
Curated region end positions: 226, 134, 134
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: Proliferating cell nuclear antigen, N-terminal domain, Proliferating cell nuclear antigen, C-terminal domain, Proliferating cell nuclear antigen, C-terminal domain
Cross-references: PDB:5H0T
Sequence:
MLEAQVQFASLWKRLVECINGLVNEANFDCNPGGLSVQAMDSSHVALVHMLLRDDCFVKYQCGRNSILGLNLASLSKVLKIVDSNDSLSLRHDDDSDVVTLTSENPEKTRKCEYQLKLLEIEAESMGIPEMDYRSTVTLNSAEFAKIVRDMQVFGDTVTIAISKEGVKFSSSGDVGQGYTFLQAAGVSDRSTKSEVKAEVKAEARDDDEEPLSRKYGKADSSANAIGVEVTMEEPITLSFALRFMGIFAKGSTLSERVTLKFAKDSPCMVEYGIDNVGYLRYYLAPKVDDAE
Protein: Glycylpeptide N-tetradecanoyltransferase
UniProt accession: Q4Q5S8
Organism: Leishmania major
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LMJF_32_0080, NMT
Length: 421 residues
Disorder content (fraction disordered): 0.023752969121140145
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 10
Curated region terms: disorder
Domain/feature annotations: Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain, Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain
Cross-references: PDB:6QD9, PDB:6QDA, PDB:6QDB, PDB:6QDC, PDB:6QDD, PDB:6QDE, PDB:6QDF, PDB:6QDG, PDB:6QDH
Sequence:
MSRNPSNSDAAHAFWSTQPVPQTEDETEKIVFAGPMDEPKTVADIPEEPYPIASTFEWWTPNMEAADDIHAIYELLRDNYVEDDDSMFRFNYSEEFLQWALCPPNYIPDWHVAVRRKADKKLLAFIAGVPVTLRMGTPKYMKVKAQEKGEGEEAAKYDEPRHICEINFLCVHKQLREKRLAPILIKEATRRVNRTNVWQAVYTAGVLLPTPYASGQYFHRSLNPEKLVEIRFSGIPAQYQKFQNPMAMLKRNYQLPSAPKNSGLREMKPSDVPQVRRILMNYLDSFDVGPVFSDAEISHYLLPRDGVVFTYVVENDKKVTDFFSFYRIPSTVIGNSNYNLLNAAYVHYYAATSIPLHQLILDLLIVAHSRGFDVCNMVEILDNRSFVEQLKFGAGDGHLRYYFYNWAYPKIKPSQVALVML
Protein: Methionine--tRNA ligase
UniProt accession: Q4QCD2
Organism: Leishmania major
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LMJF_21_0810
Length: 747 residues
Disorder content (fraction disordered): 0.014725568942436412
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 737
Curated region end positions: 747
Curated region terms: disorder
Domain/feature annotations: tRNA synthetases class I (M), Anticodon binding domain of methionyl tRNA ligase
Cross-references: PDB:3KFL
Sequence:
MLKFFTEKANHQALKAVLCAVFVQKPLEVTLGSTYSTPYLQLPKSRALLYSCNEAARLIWSTHAAPLPADNSLEGEAEWLEWESTVLTPALTPLYTHRRITGEAEAALKKLDSTIEEHQGTVAVKGAPSSTSFLVDSVLFASLLPALCEGGLLPAAQAARVPHLVKWFQAFQAEHAELIASAFDVLSVQECGDFLRVPQTYEVSPKKQKVFFATTPIYYVNASPHIGHVYSTLIVDVLGRYHRVKGEEVFVMTGTDEHGQKVAEAAAKQGVSPMDFTTSVSSEFKQCFQEMNYDMNYFIRTTNPTHEKLVQDIWKKLAAKGDIYLGKYEGWYSVSDESFLTAQNVADGVDRDGKPCKVSLESGHVVTWVEEENYMFRLSAFRERLLKYFHDHPNCIVPEFRRREVIKTVEKGLFDLSISRKRESVMNWSIPVPGDERHCIYVWLDALFNYYTGALTRVATDGTETLDEDHHALNRWPADVHVVGKDILKFHAIYWPAFLMSAELPLPERLVSHGWWTKDHKKISKSLGNAFDPVEKAKEFGIDALKYFLMRESNFQDDGDYSDKNMVARLNGELADTLGNLVSRCVAPKINVNGMWPEPAEYSESDKTLIASLNNLAGTVDHYYCLPDIQHALIAIFDVLRSLNAYVTENAPWKLVKMDTARLGTVLYVTMEGLRICTMFLQPVMPQKAKEIMDALGVPEAARVGMENYLFGIVKPGTKIAGLAEGQVVFQKVTLPTEEGERSSKGQ
Protein: Pea pathogenicity protein 2
UniProt accession: A0A175WC91
Organism: Madurella mycetomatis
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Pezizomycotina, Sordariomycetes, Sordariomycetidae, Sordariales, Sordariales incertae sedis, Madurella
Gene names: MMYC01_201259, MMYC01_203104
Length: 243 residues
Disorder content (fraction disordered): 0.06584362139917696
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 118, 118, 118, 118
Curated region end positions: 132, 132, 133, 133
Curated region terms: disorder, flexible linker, flexible linker, disorder
Domain/feature annotations: SnoaL-like domain
Cross-references: PDB:7JMR, PDB:7JMV
Sequence:
MTSPLDPHSKCYSHINGSAEELLDRLAVSELCKGWPVYRDASEWKNYRSLFTEDATVWTTWSGPRPVDEFITISKAGKEQGVFIMHRECGTLVELSPQQGRAIGKMKATITQRFSFPAASGAATNGTTGTTSDAIEFDVDCDCRFIFFCEKDTASGAWKAKYVKLFYEKDKVVSVDGHQAPKFTKDELAKYPQGYRYLGAAQARLGYDIDLQLPTSSGQLWDRMYGEMENWLGGNKVDLFWEH
Protein: Serine protease inhibitor
UniProt accession: Q26502
Organism: Schistosoma haematobium
Taxonomy: Eukaryota, Metazoa, Spiralia, Lophotrochozoa, Platyhelminthes, Trematoda, Digenea, Strigeidida, Schistosomatoidea, Schistosomatidae, Schistosoma
Length: 406 residues
Disorder content (fraction disordered): 0.03694581280788178
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 15
Curated region terms: disorder
Domain/feature annotations: Serpin (serine protease inhibitor)
Cross-references: PDB:3STO
Sequence:
MGILFTPENDDPYANISSHKAFTHAYLSTVTADFGGDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRLKSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLEKFFTDDIPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETTVSLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTVTSPIFVPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNPVLQS
Protein: Adenylosuccinate lyase
UniProt accession: G4VQX9
Organism: Schistosoma mansoni
Taxonomy: Eukaryota, Metazoa, Spiralia, Lophotrochozoa, Platyhelminthes, Trematoda, Digenea, Strigeidida, Schistosomatoidea, Schistosomatidae, Schistosoma
Length: 480 residues
Disorder content (fraction disordered): 0.020833333333333332
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 280, 280
Curated region end positions: 289, 289
Curated region terms: disorder, flexible linker
Domain/feature annotations: Lyase, Adenylosuccinate lyase C-terminus
Cross-references: PDB:5EYV
Sequence:
MDEFEEYRNPLTKRYASREMVCNFGEKRKVILWRQLWIWLAETQKELGFDITDEQINEMKSQRDSVDFGTAAAEEKARRHDVMAHVYTFALACPKAAPIIHLGATSCFVGDNADLIMLKDGLNILLPKVARCIDRLAKKAMLHKSLICLARTHLQPAQPTTMGRRICMWIQDLLLDLENLERLKNHTIRFRGAKGAVGTQASFMDLFQGDHQKVIKLDEILTKKSGFQRSWCVTGQTYPRKVDIEITNALSNIGATVHKICTDIRLLSSFHEVEEPFETKQIGSSAMPYKRNPIRSERACSLARYLMHISTSMVSTVSVQWLERSLDDSAIRRIVLPEAFLAADACLTLLQNIAEGLIVYPMVMEANLNSELPFLVVERILVKMVSEGAANRQECHERLRKHSHEAAAEIKLKGLKNSLMDKLLNDYYFAPIHSLLPTVLDPSYMIGRAVEQVEVFLNTEVDPAIHSYKDCLALNSNITI
Protein: Arginase
UniProt accession: Q6WVP6
Organism: Schistosoma mansoni
Taxonomy: Eukaryota, Metazoa, Spiralia, Lophotrochozoa, Platyhelminthes, Trematoda, Digenea, Strigeidida, Schistosomatoidea, Schistosomatidae, Schistosoma
Length: 364 residues
Disorder content (fraction disordered): 0.046703296703296704
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 17
Curated region terms: disorder
Domain/feature annotations: Arginase family
Cross-references: PDB:4Q3P
Sequence:
MLKSVATPYYPIQDEKPKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKHTVELSGSKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQTKQ
Protein: Proline--tRNA ligase
UniProt accession: Q4QDS0
Organism: Leishmania major
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LMJF_18_1220
Length: 731 residues
Disorder content (fraction disordered): 0.07250341997264022
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 288, 676
Curated region end positions: 328, 687
Curated region terms: disorder, disorder
Domain/feature annotations: tRNA synthetase class II core domain (G, H, P, S and T), Anticodon binding domain, Aminoacyl-tRNA editing domain, Prolyl-tRNA synthetase, C-terminal
Cross-references: PDB:5XIL
Sequence:
MSAKDCRGEPELLALLKELNIELPTISHGEMHTVEEANRELVQFGTPCVGTKNMFLKSKKGELVLLTAVHTTKTDMHAIEKAAGTRNLRFAPAEILSENLAVVQGCVTPFALINNIEKHNVTVLLDKNLKDSPIPFVLHPCRNDKSSLVVFEQLERFLEKVGYAYKLVDFGAASADAAVTGGAAAPAPKPKKAPADAAAAKRGGGGGGAAAPASAQSGETKLGIAAKREENFSAWYIDVITKAEMIEYYDVSGCYIIRPWAYYVWKCVQRFLGGKIEKLGVEDCYFPMFVSRSCLEREKDHIEGFAPEVAWVTRAGDTELEQPVAVRPTSETVMYPYYAKWIRSHRDLPVRLNMWNNVIRWEFSHPTPFIRTREFLWQEGHCAWAKAEECAKEVLEILECYASVYEQLLAVPVVRGRKTEKEKFAGGDYTTTVETFIEAVGRGCQGATSHNLGQNFGKMFDIRFQDPENNEQTLIPWQNSWGLSTRVIGVMIMVHGDNRGMVMPPRVASTQVIIIPVGITKDTTEEARQELLASCWRLESELCEGGVRARCDLRDNYSPGWRFNHWEVKGVPLRVELGPRELAERSLAVAVRHSGARHSVAWDAQTPAAVAALLEDVHAQMYARAKETMETHRVRVTEWTEFVPTLNRKCLILAPWCGAMECENQVKKDSAEESKVAQAQETREDARAPSMGAKTLCIPFEQPEEPAEGHECICKGCTKPATTWVLFGRSY
Protein: Putative trypanothione synthetase
UniProt accession: Q711P7
Organism: Leishmania major
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LMJF_27_1870, TRYS, tryS
Length: 652 residues
Disorder content (fraction disordered): 0.05674846625766871
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 252, 552
Curated region end positions: 262, 577
Curated region terms: disorder, disorder
Domain/feature annotations: Glutathionylspermidine synthase preATP-grasp, CHAP domain
Cross-references: PDB:2VOB
Sequence:
MSSLQRASVSFNKPGHIPFGAVQGYAPGGVPAYSNKHDHYFSGERNIEDNIFFGFKYQCVEFARRWLLVRKGLLLPDVNWACHIFQLKEVRDAATTESFAVLQVRNGTTTKPEADALLVYPSTDANPVGHVGTITEVGDDYVCVADQNYRFHKWESSCAYKLKLDHRDGIWTIIDDIDADEIEIPLGWLTFPGRANRPEGAPPVALHPSLHFKEPPKPYLLRRNFLPTESKANWLDMNNPAERLFVEEFGMDVSRTRLEEKVVSYYESNHEFHLRCVAYGTQLHAIFMEATAQVIESDEKLRLFAIPEEFWPRIRHSWKYQQTYISGRFDFAFNNETGEVKCFEYNADSASTLLECGLIQQKWAESVGLDKQDTRGSGFAVERNLKMAWANSGATGRVHFCVDEEREEQYTALYCMQAAEAVGLEGKLCILFDEFRFDDNGHVVDSDGVRVRNVWKTWMWESAITDYYAAREERGENWKPSPKDKVRLCDLLLGDDWEILYFEPMWKVIPSNKAILPMIYHNHPEHPAILKAEYELTDELRKHGYAKKPIVGRVGSNVIITSGDGVVHAESGGKYGKRNMIYQQLFELKKQDDYYAIIGGWMIGDAFSGTGIREDKSVITGVDSPFAAVRIKTDKLPHPVTLKDIDKMAEDE
Protein: Fructose-bisphosphate aldolase
UniProt accession: Q9U5N6
Organism: Leishmania mexicana
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: ald
Length: 371 residues
Disorder content (fraction disordered): 0.03504043126684636
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 358
Curated region end positions: 370
Curated region terms: disorder
Domain/feature annotations: Fructose-bisphosphate aldolase class-I
Cross-references: PDB:1EPX
Sequence:
MSRVTVLQSQLPAYNRLKTPYESELIATVKKLTTPGKGLLAADESIGSCTKRFQPIGLSNTEEHRRQYRALMLEAEGFEQYISGVILHDETVGQKASNGQTFPEYLTARGVVPGIKTDMGLCPLLEGAEGEQMTEGLDGYVKRASAYYKKGCRFCKWRNVYKIQNGTVSESAVRFNAETLARYAILSQMSGLVPIVEPEVMIDGKHDIDTCQRVSEHVWREVVAALQRHGVIWEGCLLKPNMVVPGAESGKTAAPEQVAHYTVMTLARTMPAMLPGVMFLSGGLSEVQASEYLNAINNSPLPRPYFLSFSYARALQSSALKAWGGKESGLAAGRRAFLHRARMNSMAQLGKYKRSDDDASSSSLYVKGNTY
Protein: Glucose-6-phosphate isomerase
UniProt accession: P42861
Organism: Leishmania mexicana
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: PGI
Length: 605 residues
Disorder content (fraction disordered): 0.07933884297520662
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 48
Curated region terms: disorder
Domain/feature annotations: Phosphoglucose isomerase
Cross-references: PDB:1T10
Sequence:
MSDYFSKLKEHVVESTEINGCTPSIATATFNAPYEVARKTKMLGVTDSSLLNLPAWKRLQSLYEKYGNDSILSHFEKDHQRFQRYSIEIDLHSDDNFLFLDYSKSHINDEIKDALVALAEERGVRAFAKAMFDGQRVNSTENRAVLHVALRNRSNRPIIVDGKDVMSDVNNVLAQMKDFTERVRSGEWKGQTGKSIYNIVNIGIGGSDLGPVMVTEALKPFSKRDLHCFFVSNVDGTHMAEVLKQVNLEETIFIIASKTFTTQETLTNAMSARNALMSYLKENGISTDGAVAKHFVALSTNTEKVREFGIDTVNMFAFWDWVGGRYSVWSAIGLSVMLSIGYDNFVEFLTGAHVMDNHFASTPTEQNLPMMLALVGIWYNNFFGSETQAVLPYDQYLWRLPAYLQQLDMESNGKGVTKKSGAVAVQTGPIVFGEAGTNGQHAFYQLIHQGTKIIPCDFIGCVQTQNRVGDHHRTLMSNFFAQTEALMVGKNAEEVRQELVKSGMSGDAIENMIPHKTFTGSRPSNSILVNALTPRALGAIIAMYEHKVLVQGAIWGINSYDQWGVELGKVLAKSILPQLKSGNIVSDHDGSTNGLINMFNTRAHL
Protein: Fructose-bisphosphatase
UniProt accession: O97193
Organism: Leishmania major
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: FBP, LMJF_04_1160
Length: 351 residues
Disorder content (fraction disordered): 0.08831908831908832
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 340, 52, 52, 61
Curated region end positions: 351, 70, 61, 70
Curated region terms: disorder, disorder, disorder to order, disorder
Domain/feature annotations: Fructose-1-6-bisphosphatase, N-terminal domain, Fructose-1-6-bisphosphatase, C-terminal domain
Cross-references: PDB:5OEY, PDB:5OEZ, PDB:5OFU
Sequence:
MDVRRTPTPTTLTQYIIKSQPPHSRGDFTLLMMAIQTSVKVIEKNIRRAGMKGMLGYIAGQSANATGDHQAKLDVISNIAFKAYLLSSTSVCVLGSEEEEQMIIAESGRRGDYLIFFDPLDGSSNIDANVSVGSIWGVWRLPKDTTINSVEDANAVIRMLKGTDMVSAGYAVYGSATNLVLTSGHGVDGFTLDPNIGEFILTHPHISIPKKRSIYSVNEGNYGKWEPWFKEYIDYLKMNKTTRYSARYIGSMVGDIHRTLLYGGIFCYPKDANQVEGKLRLLYEAAPMAMIVEQAGGKAVGSNGRILEQSITRLHQRTPVYFGSRQEVDLCMAFRDRNVKTEALAPTSSKL