LiteFold/DisProt huggingface dataset:
Protein: Transcription termination/antitermination protein NusG
UniProt accession: P0AFG0
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3945, b3982, nusG
Length: 181 residues
Disorder content (fraction disordered): 0.19889502762430936
Curated region start positions: 117, 117, 45
Curated region end positions: 131, 131, 65
Curated region terms: disorder, flexible linker, disorder
Domain/feature annotations: 2.30.30.30, NusG, N-terminal domain, KOW motif, Transcription termination factor nusG
Cross-references: PDB:2JVV, PDB:2K06
Sequence:
MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMVPTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAPISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKVSVSIFGRATPVELDFSQVEKA
Protein: Gliotactin
UniProt accession: Q9NK80
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: CG3903, Gli
Length: 956 residues
Disorder content (fraction disordered): 0.2165271966527197
Curated region start positions: 750, 750, 750
Curated region end positions: 956, 956, 956
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: alpha/beta hydrolase, Carboxylesterase family
Sequence:
MMHKLKYRDKLKWLLALLVLIGTCFIQTRGQTRDPRFYSRPGVDYHWPNPGDPDYRTYTFNDRRYGHYQPNGYGANYPGRNPPGQYPQGMPNEDRFRFDPNDPNARTQFPGVLAGWREDLQGKQRRDSLTLERDVFVTTNYGQVQGFKVYMYDNPDPKSFYRPYHSTVDRVMGECSVFLGIPYALPPTFEGRFKPPRVHRGWQLLQAVDFGPACPQPVRYTGATKGIMDMDEDCLYLNVYSPKTGAGVAQKYPVMVYIHGGEFIRGASNLFQGHILASFYDVVVVTLNYRLGALGFLSTGDENSPGNYGILDQAMALRWVYDNIEFFNGDRNSITLFGPGAGGASAGLLMVAPQTRNIVRRVIAQSGSALADWALIQDKYRAQNTSRVLGQLLGCSIESSWKLVNCLRTGRSFYELGNAEFSPQVGSFPWGPVLDHNFTLPGDDWYEGWREKDWRFLTKTPETLIRAGKFNRNIQYMTGVTTQEAAFFVAQNESLSPYYELDGRFFDQKIREHVFRYNYTLNPNGVYEAIKYMYTFWPDPNNNTIIRDQYINMLSDLYYRAPVDQMVKLMLEQKVPVYMYVLNTTVEALNLPQWRKYPHDIERYFLTGAPFMDTEFFPKKEHLQRNMWTDNDRNMSHFFMQTYTNFARYGNPTPQQVLGMHFQRAYQGEIRYLNINTTYNSSILLNYRQTECAFWTQYLPTVIGVLVPTYPPTTEYWWEPKEPLQIAFWSMSVACFFLIVLVVICCIMWRNAKRQSDRFYDEDVFINGEGLEPEQDTRGVDNAHMVTNHHALRSRDNIYEYRDSPSTKTLASKAHTDTTSLRSPSSLAMTQKSSSQASLKSGISLKETNGHLVKQSERAATPRSQQNGSIAKVASPPVEEKRLLQPLSSTPVTQLQAEPAKRVPTAASVSGSSRSTTPVPSARSTTTHTTTATLSSQPAAQPRRTHLVEGVPQTSV
Protein: Vesicle-associated membrane protein 4
UniProt accession: O70480
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Vamp4
Length: 141 residues
Disorder content (fraction disordered): 0.5035460992907801
Curated region start positions: 47, 47, 47
Curated region end positions: 117, 117, 117
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: 1.20.5.110, Synaptobrevin
Cross-references: pdb:2nps
Sequence:
MPPKFKRHLNDDDVTGSVKSERRNLLEDDSDEEEDFFLRGPSGPRFGPRNDKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQLRRQMWWRGCKIKAIMALAAAILLLMIIILIVVKFRT
Protein: Vesicle transport through interaction with t-SNAREs homolog 1A
UniProt accession: Q9JI51
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Vti1a, Vti1l2
Length: 224 residues
Disorder content (fraction disordered): 0.3482142857142857
Curated region start positions: 115, 115, 115
Curated region end positions: 192, 192, 192
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: t-snare proteins, 1.20.5.110, Vesicle transport v-SNARE protein N-terminus, Snare region anchored in the vesicle membrane C-terminus
Cross-references: pdb:2nps
Sequence:
MSADFEGYEQDFAVLTAEITSKISRVPRLPPDEKKQMVANVEKQLEEARELLEQMDLEVREIPPQSRGMYSNRMRSYKQEMGKLETDFKRSRIAYSDEVRNELLGDAGNSSENQLIKLREERAHLLDNTERLERSSRRLEAGYQIAVETEQIGQEMLENLSHDRERIQRARERLRETDANLGKSSRILTGMLRRIIQNRILLVILGIIVVITILTAITFFVRGH
Protein: Syntaxin-6
UniProt accession: Q5R6Q2
Organism: Pongo abelii
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Pongo
Gene names: STX6
Length: 255 residues
Disorder content (fraction disordered): 0.25098039215686274
Curated region start positions: 169, 169, 169
Curated region end positions: 232, 232, 232
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: 1.20.58.90, 1.20.5.110, SNARE domain, Syntaxin 6/10/61, N-terminal
Cross-references: pdb:2nps
Sequence:
MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL
Protein: Syntaxin-12
UniProt accession: G3V7P1
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Stx12, Stx13
Length: 274 residues
Disorder content (fraction disordered): 0.2518248175182482
Curated region start positions: 182, 182, 182
Curated region end positions: 250, 250, 250
Curated region terms: disorder, protein binding, disorder to order
Domain/feature annotations: 1.20.5.110, 1.20.58.70, SNARE domain, Syntaxin-like protein
Cross-references: pdb:2nps
Sequence:
MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQFQHSTNQLAKETNELLKELGSLPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQDLELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK
Protein: Synaptobrevin homolog 2
UniProt accession: P33328
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: SNC2, YOR327C
Length: 115 residues
Disorder content (fraction disordered): 0.7913043478260869
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 91, 91, 91, 91
Curated region terms: disorder, disorder to order, protein binding, molecular adaptor activity
Domain/feature annotations: 1.20.5.110, Synaptobrevin
Sequence:
MSSSVPYDPYVPPEESNSGANPNSQNKTAALRQEIDDTVGIMRDNINKVAERGERLTSIEDKADNLAISAQGFKRGANRVRKQMWWKDLKMRMCLFLVVIILLVVIIVPIVVHFS
Protein: Protein SSO1
UniProt accession: P32867
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: P1405, SSO1, YPL232W
Length: 290 residues
Disorder content (fraction disordered): 0.25517241379310346
Curated region start positions: 192, 192, 192
Curated region end positions: 265, 265, 265
Curated region terms: disorder, disorder to order, protein binding
Domain/feature annotations: 1.20.58.70, Syntaxin, SNARE domain
Cross-references: PDB:3b5n
Sequence:
MSYNNPYQLETPFEESYELDEGSSAIGAEGHDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVNEEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTNKQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR
Protein: Protein SSO2
UniProt accession: P39926
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: SSO2, YM8010.13C, YMR183C
Length: 295 residues
Disorder content (fraction disordered): 0.25084745762711863
Curated region start positions: 196
Curated region end positions: 269
Curated region terms: disorder
Domain/feature annotations: 1.20.58.70, Syntaxin, SNARE domain
Sequence:
MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVSEEQEMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSNKQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK
Protein: Glutathione S-transferase A1
UniProt accession: P08263
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GSTA1
Length: 222 residues
Disorder content (fraction disordered): 0.06756756756756757
Curated region start positions: 208, 208, 208
Curated region end positions: 222, 222, 222
Curated region terms: disorder, disorder to order, molecular function regulator
Domain/feature annotations: 1.20.1050.10, Glutaredoxin, Glutathione S-transferase, C-terminal domain, Glutathione S-transferase, N-terminal domain
Cross-references: PDB:1GSD, PDB:1GSE, PDB:1GSF
Sequence:
MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAKLALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
Protein: GRB2-associated-binding protein 2
UniProt accession: Q9UQC2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GAB2, KIAA0571
Length: 676 residues
Disorder content (fraction disordered): 0.03106508875739645
Curated region start positions: 504, 504
Curated region end positions: 524, 524
Curated region terms: disorder, protein binding
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), PH domain
Sequence:
MSGGGDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL
Protein: Ribosomal protein S6 kinase alpha-1
UniProt accession: Q15418
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MAPKAPK1A, RPS6KA1, RSK1
Length: 735 residues
Disorder content (fraction disordered): 0.08843537414965986
Curated region start positions: 683, 683, 683, 683, 712, 730, 730, 696, 709, 731, 577, 729, 730, 725, 725, 712
Curated region end positions: 735, 735, 735, 735, 727, 735, 735, 735, 735, 735, 588, 735, 735, 729, 732, 726
Curated region terms: disorder, protein binding, disorder, protein binding, protein binding, PDZ domain binding, phosphorylation display site, disorder, disorder, phosphorylation display site, disorder, PDZ domain binding, PDZ domain binding, self-interaction, self-regulatory activity, mitogen-activated protein kinase binding
Domain/feature annotations: Transferase(Phosphotransferase) domain 1, Phosphorylase Kinase; domain 1, Transferase(Phosphotransferase) domain 1, Phosphorylase Kinase; domain 1, Protein kinase domain, Protein kinase domain, Protein kinase C terminal domain
Cross-references: BMRB:27213, BMRB:27214, ELM:DOC_MAPK_gen_1, PDB:3RNY, PDB:4H3P, PDB:4h3p, PDB:5CSF, PDB:5N7D, PDB:5N7F, PDB:5N7G
Sequence:
MPLAQLKEPWPLMELVPLDPENGQTSGEEAGLQPSKDEGVLKEISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLPQSQLSHQDLQLVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKLPSTTL
Protein: Uncharacterized protein
UniProt accession: O25010
Organism: Helicobacter pylori (strain ATCC 700392 / 26695)
Taxonomy: Bacteria, Proteobacteria, Epsilonproteobacteria, Campylobacterales, Helicobacteraceae, Helicobacter
Gene names: HP_0222
Length: 73 residues
Disorder content (fraction disordered): 0.410958904109589
Curated region start positions: 1, 1
Curated region end positions: 30, 30
Curated region terms: disorder, disorder
Domain/feature annotations: Met repressor-like, Transcriptional regulator, RHH-like, CopG
Sequence:
MEKTENTDETRLRGTKNKLGRKPKADANKKTRAVSLYFSDEQYQKLEKMANEEEESVGSYIKRYILKALRKIE
Protein: Transcriptional repressor arc
UniProt accession: P03050
Organism: Salmonella phage P22
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Uroviricota, Caudoviricetes, Caudovirales, Podoviridae, Lederbergvirus
Gene names: arc
Length: 53 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 53, 53, 53, 53
Curated region terms: disorder, protein binding, disorder to order, disorder
Domain/feature annotations: Met repressor-like, Arc-like DNA binding domain
Cross-references: PDB:1ARQ
Sequence:
MKGMSKMPQFNLRWPREVLDLVRKVAEENGRSVNSEIYQRVMESFKKEGRIGA
Protein: Tubulin gamma chain
UniProt accession: P53378
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: L8167.21, TUB4, YLR212C
Length: 473 residues
Disorder content (fraction disordered): 0.07399577167019028
Curated region start positions: 439, 439
Curated region end positions: 473, 473
Curated region terms: disorder, phosphorylation display site
Domain/feature annotations: Helix hairpin bin, Tubulin/FtsZ, C-terminal domain, Tubulin/FtsZ, GTPase domain, Tubulin/FtsZ family, GTPase domain, Tubulin C-terminal domain
Sequence:
MGGEIITLQAGQCGNHVGKFLWSQLAKEHAIGTDGLSQLPDSSTERDDDTKPFFRENSRNKFTPRAIMMDSEPSVIADVENTFRGFFDPRNTWVASDGASAGNSWANGYDIGTRNQDDILNKIDKEIDSTDNFEGFQLLHSVAGGTGSGLGSNLLEALCDRYPKKILTTYSVFPARSSEVVVQSYNTILALRRLIEDSDATVVFDNASLLNISGKVFRNPNIDLQHTNQLISTIISSVTNSIRFPSYMYSSMSSIYSTLIPSPELHFLSPSFTPFTSDYIHDDIAHKGHSSYDVMLDLLDPSNSLVSTAMNNPTYFNVYNTIIGNVEPRQISRAMTKLQQRIKFPSWSSSAMHVNIGRRSPYLPLQPNENEVSGMMLSNMSTVVNVFENACNTFDKVFAKGAFLNNYNVGDLFQSMQNVQDEFAESREVVQSLMEDYVAAEQDSYLDDVLVDDENMVGELEEDLDADGDHKLV
Protein: Protein STE50
UniProt accession: P25344
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: STE50, YCL032W, YCL32W
Length: 346 residues
Disorder content (fraction disordered): 0.18208092485549132
Curated region start positions: 187
Curated region end positions: 249
Curated region terms: disorder
Domain/feature annotations: Transcription Factor, Ets-1, Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, Ras association (RalGDS/AF-6) domain, Ste50p, sterile alpha motif
Sequence:
MEDGKQAINEGSNDASPDLDVNGTILMNNEDFSQWSVDDVITWCISTLEVEETDPLCQRLRENDIVGDLLPELCLQDCQDLCDGDLNKAIKFKILINKMRDSKLEWKDDKTQEDMITVLKNLYTTTSAKLQEFQSQYTRLRMDVLDVMKTSSSSSPINTHGVSTTVPSSNNTIIPSSDGVSLSQTDYFDTVHNRQSPSRRESPVTVFRQPSLSHSKSLHKDSKNKVPQISTNQSHPSAVSTANTPGPSPNEALKQLRASKEDSCERILKNAMKRHNLADQDWRQYVLVICYGDQERLLELNEKPVIIFKNLKQQGLHPAIMLRRRGDFEEVAMMNGSDNVTPGGRL
Protein: Protein OPY2
UniProt accession: Q06810
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: OPY2, YPR075C
Length: 360 residues
Disorder content (fraction disordered): 0.4222222222222222
Curated region start positions: 194, 267, 325, 325, 325
Curated region end positions: 333, 345, 339, 339, 339
Curated region terms: disorder, disorder, protein binding, protein binding, protein binding
Domain/feature annotations: Opy2 protein
Sequence:
MSSSSKASASSSLSSTATSSTSATRGSDGCVVCDSTASCPVCASGEYCVMTSLTCDKCPSTYCAKQSDSQLSSLSSSSSSSSSSNSNEKTSLIVGFTVGIVGGAMLIALVALYFINKRYWKPKRQKNKALKLEEASQSYGNEEEYFDDEDDDDEDDEDDGGMRKDESHTLFNTSLVPPTLNVPGNRSSASTTRTRASNILPIAYIPGVTSGLSTDKLQSKLRSSSKRQNAAGDIRSHITLGSSILDGLDDEDDEHNQVLNKDADDNLITAIRAKPKLVQIAEEESDKEIQDLDVIEEQTEADDLSHMAKSEASHGNNDEDDDEEGSFILDLEIPESIRESTQGSRTESPFEDKFEIHDER
Protein: Isoform 10 of Pro-neuregulin-1, membrane-bound isoform
UniProt accession: Q02297-10
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GGF, HGL, HRGA, NDF, NRG1, SMDF
Length: 296 residues
Disorder content (fraction disordered): 0.2533783783783784
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 75, 75, 75, 75, 75
Curated region terms: disorder, disorder, disorder, nickel cation binding, zinc ion binding
Sequence:
MEIYSPDMSEVAAERSSSPSTQLSADPSLDGLPAAEDMPEPQTEDGRTPGLVGLAVPCCACLEAERLRGCLNSEKICIVPILACLVSLCLCIAGLKWVFVDKIFEYDSPTHLDPGGLGQDPIISLDATAASAVWVSSEAYTSPVSRAQSESEVQVTVQGDKAVVSFEPSAAPTPKNRIFAFSFLPSTAPSFPSPTRNPEVRTPKSATQPQTTETNLQTAPKLSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLPE
Protein: Ermin
UniProt accession: Q5RJL0
Organism: Rattus norvegicus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Rattus
Gene names: Ermn
Length: 282 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 282, 282, 282, 282, 282
Curated region terms: disorder, protein binding, disorder, disorder, disorder
Domain/feature annotations: Ermin
Sequence:
MTDTPVTLSGSECNGDRPPENGQQPSSQTRKTTDADETQTYYGVEPSLQHLPAKENQEESGNSKGNVLPRGSEDEKILNENTEENLFVVHQAIQDLSLQETSAEDTVFQEGHPWKKIPLNSHNLDMSRQKERIVHQHLEQREDESAAHQATEIEWLGFQKSSQVDILHSKCDEEEEVWNEEINEEDVDECAEDEGEDEVRVIEFKRKYREGSPLKEESLAREDSPLSSPSSQPGTPDEQLVLGKKGDIARNSYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Protein: Fizzy-related protein homolog
UniProt accession: Q9UM11
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CDH1, FYR, FZR, FZR1, KIAA1242
Length: 496 residues
Disorder content (fraction disordered): 0.1814516129032258
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 68, 109, 133
Curated region end positions: 41, 87, 124, 145
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: YVTN repeat-like/Quinoprotein amine dehydrogenase, CDC20/Fizzy WD40 domain
Cross-references: PDB:4UI9
Sequence:
MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRINENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTYSLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR
Protein: Anaphase-promoting complex subunit 2
UniProt accession: Q9UJX6
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ANAPC2, APC2, KIAA1406
Length: 822 residues
Disorder content (fraction disordered): 0.20924574209245744
Curated region start positions: 1, 30, 221, 459, 305, 731
Curated region end positions: 14, 52, 231, 475, 319, 822
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain, Cullin Repeats, Cullin; Chain C, Domain 2, Anaphase promoting complex (APC) subunit 2, ANAPC2-like, TPR repeats, Cullin alpha+beta domain
Cross-references: PDB:4UI9, PDB:5A31, PDB:5G04, PDB:5G05
Sequence:
MAAAVVVAEGDSDSRPGQELLVAWNTVSTGLVPPAALGLVSSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLESRLDPYLRSLELLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQCWCRQALEQFHQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDGPARPASPEAGNTLRRWRCHVQRFFYRIYASLRIEELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPASLETGQDSEDDSGEPEDWVPDPVDADPGKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVILLYFQDQASWTLEELSKAVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS
Protein: Uncharacterized protein MJ0480
UniProt accession: Q57904
Organism: Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Taxonomy: Archaea, Euryarchaeota, Methanomada group, Methanococci, Methanococcales, Methanocaldococcaceae, Methanocaldococcus
Gene names: MJ0480
Length: 198 residues
Disorder content (fraction disordered): 0.2828282828282828
Curated region start positions: 46, 46
Curated region end positions: 101, 101
Curated region terms: disorder, small molecule binding
Domain/feature annotations: Integral membrane protein EMC3/TMCO1-like
Cross-references: PDB:5C8J
Sequence:
MFGSIFDIYYKTLDAIFMPIIKVLHPALAILIIAIIVSLIINIATKLLVDQKRVAELKKEIQEFQVKFKKMSKNPEMMEKLQEEQQRIMQLNAELMKMSFRPMIYTWVPIILIFIYLRHVYGFGGVYQELNPGWNGVVVYLPIILSKILFIDFWHWLGSIFYKGGFKIVSNTALGWLGWYILCSFATSTVLRKILGIK
Protein: Tyrosine-protein phosphatase YopH
UniProt accession: P15273
Organism: Yersinia enterocolitica
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Yersiniaceae, Yersinia
Gene names: yop51, yopH
Length: 468 residues
Disorder content (fraction disordered): 0.06623931623931624
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 20, 21
Curated region end positions: 50, 35
Curated region terms: disorder, disorder
Domain/feature annotations: Protein-tyrosine phosphatase, YopH, N-terminal domain, Protein tyrosine phosphatase superfamily, Protein-tyrosine phosphatase, YopH, N-terminal
Cross-references: PDB:4GF3
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS