LiteFold/DisProt huggingface dataset:
Protein: Peroxisomal biogenesis factor 19
UniProt accession: P40855
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HK33, OK/SW-cl.22, PEX19, PXF
Length: 299 residues
Disorder content (fraction disordered): 0.6755852842809364
Curated region start positions: 1, 1, 1, 1, 4, 278
Curated region end positions: 165, 165, 165, 165, 182, 297
Curated region terms: disorder, protein binding, disorder, protein binding, disorder, disorder
Domain/feature annotations: Pex19, mPTS binding domain, Pex19 protein family
Sequence:
MAAAEEGCSVGAEADRELEELLESALDDFDKAKPSPAPPSTTTAPDASGPQKRSPGDTAKDALFASQEKFFQELFDSELASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRVGSDMTSQQEFTSCLKETLSGLAKNATDLQNSSMSEEELTKAMEGLGMDEGDGEGNILPIMQSIMQNLLSKDVLYPSLKEITEKYPEWLQSHRESLPPEQFEKYQEQHSVMCKICEQFEAETPTDSETTQKARFEMVLDLMQQLQDLGHPPKELAGEMPPGLNFDLDALNLSGPPGASGEQCLIM
Protein: Large envelope protein
UniProt accession: Q67953
Organism: Hepatitis B virus
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Blubervirales, Hepadnaviridae, Orthohepadnavirus
Gene names: S
Length: 445 residues
Disorder content (fraction disordered): 0.24269662921348312
Dataset labels: Viral proteins
Curated region start positions: 1, 1, 1, 1, 66, 72
Curated region end positions: 108, 108, 108, 108, 92, 90
Curated region terms: disorder, protein binding, disorder, disorder, protein binding, disorder to order
Domain/feature annotations: Major surface antigen from hepadnavirus
Sequence:
MQLIITSKLGIIYILCGRLAFYIREKLHAVPHFVGHHILGNKSYSMGGWSSKPRQGMGTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEAKQVGAGAFGPGFTPPHGGLLGWSPQAQGTLTTVPAAPPPASTNRQSGRQPTPISPPLRDSHPQAMQWNSTTFHQALLDPRVRGLYFPAGGSSSGTVNPVPTTASPISSIFSRTGDPAPNMESTTSGFLGPLLVLQAGFFLLTRILTIPQSLDSWLTSLNFLGGTPKCPGQNSQSPTSNHSPTSCPPTCPGYRWMCLRRFIIFLFILLLCLIFLLVLLDYKGMLPVCPLLPGTSTTSTGPCKTCTIPAQNTSMFPSCCCTKPSDGNCTCIPIPSSWAFARFLWEWASVRFSWLSLLVPFVQWSAGLSPTVWLSVIWTMWYWGPSLYNILSPFLPLLPILCCLWAYI
Protein: DNA polymerase delta subunit 2
UniProt accession: P49005
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: POLD2
Length: 469 residues
Disorder content (fraction disordered): 0.07036247334754797
Curated region start positions: 42, 102
Curated region end positions: 53, 122
Curated region terms: disorder, disorder
Domain/feature annotations: 3.60.21.50, 2.40.50.430, DNA polymerase alpha/epsilon subunit B, DNA polymerase delta subunit OB-fold domain
Cross-references: PDB:3E0J
Sequence:
MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFLENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPDDELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRFVLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINKAKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTLQLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKTDPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPISFSGFGAEDDDLGGLGLGP
Protein: Osteopontin
UniProt accession: Q9I832
Organism: Coturnix japonica
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Archelosauria, Archosauria, Dinosauria, Saurischia, Theropoda, Coelurosauria, Aves, Neognathae, Galloanserae, Galliformes, Phasianidae, Perdicinae, Coturnix
Gene names: OPN
Length: 264 residues
Disorder content (fraction disordered): 1
Curated region start positions: 90, 90, 90, 1
Curated region end positions: 120, 120, 120, 264
Curated region terms: disorder, order to disorder, protein binding, disorder
Domain/feature annotations: Osteopontin
Sequence:
MKLTLLCLCFISITAAWPVSKSKQHAISASSEEKYDPRSHHTHRYHQDHVDSQSQEHLQQTQNDLASLQQTHYSSEENADVPEQPDFPDVPSKSQETVDDDDDDDNDSNDTDESDEVFTDFPTEAPVAPFNRGDNAGRGDSVAYGFRAKAHVVKASKIRKAARKLIEDDATTEDGDSQPAGLWWPKESREQNSRELPQHQSVENDSRPKFDSREVDGGDSKASAGVDSRESQGSVPAVDASNQTLESAEDAEDRHSIENNEVTR
Protein: Histone-lysine N-methyltransferase EZH2
UniProt accession: Q15910
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: EZH2, KMT6
Length: 746 residues
Disorder content (fraction disordered): 0.24932975871313673
Dataset labels: Cancer-related proteins, NDDs-related proteins, RNA-binding proteins
Curated region start positions: 346, 480, 730, 183, 732, 733, 386, 1, 480, 487, 507, 497, 340, 367
Curated region end positions: 421, 514, 746, 210, 746, 746, 420, 10, 514, 513, 511, 513, 435, 375
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, flexible linker, disorder, disorder to order, nucleosome binding, methylation display site, histone binding, disorder, RNA binding
Domain/feature annotations: 1.20.58.1880, SET domain, SET domain, WD repeat binding protein EZH2, Polycomb repressive complex 2 tri-helical domain, CXC domain, Ezh2, MCSS domain
Cross-references: BMRB:51420, EMDB:EMD-21707, PDB:4MI0, PDB:4MI5, PDB:5HYN, PDB:6WKR
Sequence:
MGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
Protein: DNA topoisomerase 2-associated protein PAT1
UniProt accession: P25644
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: MRT1, PAT1, YCR077C, YCR77C
Length: 796 residues
Disorder content (fraction disordered): 0.11683417085427136
Dataset labels: Condensates-related proteins, RNA-binding proteins
Curated region start positions: 422, 5, 55
Curated region end positions: 469, 24, 79
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Topoisomerase II-associated protein PAT1, Topoisomerase II-associated protein PAT1
Cross-references: PDB:4BRW, PDB:4N0A
Sequence:
MSFFGLENSGNARDGPLDFEESYKGYGEHELEENDYLNDETFGDNVQVGTDFDFGNPHSSGSSGNAIGGNGVGATARSYVAATAEGISGPRTDGTAAAGPLDLKPMESLWSTAPPPAMAPSPQSTMAPAPAPQQMAPLQPILSMQDLERQQRQMQQQFMNFHAMGHPQGLPQGPPQQQFPMQPASGQPGPSQFAPPPPPPGVNVNMNQMPMGPVQVPVQASPSPIGMSNTPSPGPVVGATKMPLQSGRRSKRDLSPEEQRRLQIRHAKVEKILKYSGLMTPRDKDFITRYQLSQIVTEDPYNEDFYFQVYKIIQRGGITSESNKGLIARAYLEHSGHRLGGRYKRTDIALQRMQSQVEKAVTVAKERPSKLKDQQAAAGNSSQDNKQANTVLGKISSTLNSKNPRRQLQIPRQQPSDPDALKDVTDSLTNVDLASSGSSSTGSSAAAVASKQRRRSSYAFNNGNGATNLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSSYDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNVSFLTTSKIGLNLITILISRAALIKQDSSRSNILSSPEISTWNEIYDKLFTSLESKIQLIFPPREYNDHIMRLQNDKFMDEAYIWQFLASLALSGKLNHQRIIIDEVRDEIFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMGLVYRDGEISELK
Protein: AGAP008004-PA
UniProt accession: Q7Q3R9
Organism: Anopheles gambiae
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Nematocera, Culicoidea, Culicidae, Anophelinae, Anopheles
Gene names: 1277947, AgaP_AGAP008004
Length: 103 residues
Disorder content (fraction disordered): 0.7961165048543689
Curated region start positions: 22, 22, 85, 56, 56, 56, 56
Curated region end positions: 103, 103, 103, 84, 84, 84, 84
Curated region terms: disorder, disorder, disorder, disorder, disorder to order, protein binding, molecular function inhibitor activity
Domain/feature annotations: Thrombin inhibitor from mosquito
Cross-references: PDB:5NHU
Sequence:
MASKLFVLAFLCLALVVVVQSAPQYARGDVPTYDEEDFDEESLKPHSSSSSDDGEEEFDPSLLEEHADAPTARDPGRNPEFLRNSNTDEQASAPAASSSESDE
Protein: Variegin
UniProt accession: P85800
Organism: Amblyomma variegatum
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Chelicerata, Arachnida, Acari, Parasitiformes, Ixodida, Ixodoidea, Ixodidae, Amblyomminae, Amblyomma
Length: 32 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 8, 11, 11, 11, 15, 12, 12, 12, 12
Curated region end positions: 32, 32, 32, 32, 32, 32, 28, 28, 28, 28
Curated region terms: disorder, disorder, disorder, protein binding, molecular function inhibitor activity, disorder, disorder, protein binding, disorder to order, molecular function inhibitor activity
Cross-references: PDB:3B23
Sequence:
SDQGDVAEPKMHKTAPPFDFEAIPEEYLDDES
Protein: Uncharacterized protein avahiru
UniProt accession: Q6F3E8
Organism: Amblyomma variegatum
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Chelicerata, Arachnida, Acari, Parasitiformes, Ixodida, Ixodoidea, Ixodidae, Amblyomminae, Amblyomma
Gene names: avahiru
Length: 219 residues
Disorder content (fraction disordered): 0.045662100456621
Curated region start positions: 147, 147, 147, 147
Curated region end positions: 156, 156, 156, 156
Curated region terms: disorder, protein binding, disorder to order, molecular function inhibitor activity
Cross-references: PDB:5GIM
Sequence:
MLKNIVLLLAAGLSGPAVLAKPKWSPLFEEATNALEARSGGHQTAVPKVSKQGLGGDFEEIPSDEIIKRALEDRSGGHQTAVPKISKQGLGGDFEEIPSDEIIERALEARSDGHQTAVPKMSKQGLGGDIEEIPSDEIIERALEARSGGHQTAVPKMSKQGLGGDSEEIPSNEIIERALEARSGGHETAVPKMSKQGLGGDFEEIPSDEIIERALQARG
Protein: TP53-regulated inhibitor of apoptosis 1
UniProt accession: O43715
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: 15E1.1, HSPC132, TRIAP1
Length: 76 residues
Disorder content (fraction disordered): 0.3026315789473684
Curated region start positions: 54
Curated region end positions: 76
Curated region terms: disorder
Domain/feature annotations: Uncharacterised protein family (UPF0203)
Cross-references: PDB:4XZS
Sequence:
MNSVGEACTDMKREYDQCFNRWFAEKFLKGDSSGDPCTDLFKRYQQCVQKAIKEKEIPIEGLEFMGHGKEKPENSS
Protein: Integrin beta-1-binding protein 1
UniProt accession: O14713
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: ICAP1, ITGB1BP1
Length: 200 residues
Disorder content (fraction disordered): 0.055
Curated region start positions: 49, 49
Curated region end positions: 59, 59
Curated region terms: disorder, disorder
Domain/feature annotations: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB), Beta-1 integrin binding protein
Cross-references: PDB:4DX8, PDB:4JIF
Sequence:
MFRKGKKRHSSSSSQSSEISTKSKSVDSSLGGLSRSSTVASLDTDSTKSSGQSNNNSDTCAEFRIKYVGAIEKLKLSEGKGLEGPLDLINYIDVAQQDGKLPFVPPEEEFIMGVSKYGIKVSTSDQYDVLHRHALYLIIRMVCYDDGLGAGKSLLALKTTDASNEEYSLWVYQCNSLEQAQAICKVLSTAFDSVLTSEKP
Protein: Malate synthase G
UniProt accession: P37330
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW2943, b2976, glc, glcB
Length: 723 residues
Disorder content (fraction disordered): 0.015214384508990318
Curated region start positions: 300
Curated region end positions: 310
Curated region terms: disorder
Domain/feature annotations: Malate synthase G - maily-beta sub-domain, Malate synthase, domain III, Malate synthase, domain 3, Malate synthase, TIM barrel domain, Malate synthase, N-terminal domain, Malate synthase G, alpha-beta insertion domain, Malate synthase, C-terminal
Cross-references: PDB:1D8C
Sequence:
MSQTITQSRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVHDLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQPERVTVETTGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDPQRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVGYRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVAAVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSLLFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPKMHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFINTGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGMWAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFNAEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAGNFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH
Protein: Peptide YY
UniProt accession: P68005
Organism: Sus scrofa
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Suina, Suidae, Sus
Gene names: PYY
Length: 36 residues
Disorder content (fraction disordered): 0.3611111111111111
Curated region start positions: 1
Curated region end positions: 13
Curated region terms: disorder
Domain/feature annotations: Pancreatic hormone peptide
Cross-references: PDB:1RU5
Sequence:
YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY
Protein: Protein transport protein SEC31
UniProt accession: P38968
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: D1229, SEC31, WEB1, YDL195W
Length: 1273 residues
Disorder content (fraction disordered): 0.26001571091908876
Curated region start positions: 770
Curated region end positions: 1100
Curated region terms: disorder
Domain/feature annotations: YVTN repeat-like/Quinoprotein amine dehydrogenase, 1.25.40.980, Functional domain of the splicing factor Prp18, 2.20.25.400, WD domain, G-beta repeat, WD domain, G-beta repeat, Steroid receptor RNA activator (SRA1), Protein transport protein SEC31, Sec16 Sec23-binding domain
Cross-references: PDB:4BZJ
Sequence:
MVKLAEFSRTATFAWSHDKIPLLVSGTVSGTVDANFSTDSSLELWSLLAADSEKPIASLQVDSKFNDLDWSHNNKIIAGALDNGSLELYSTNEANNAINSMARFSNHSSSVKTVKFNAKQDNVLASGGNNGEIFIWDMNKCTESPSNYTPLTPGQSMSSVDEVISLAWNQSLAHVFASAGSSNFASIWDLKAKKEVIHLSYTSPNSGIKQQLSVVEWHPKNSTRVATATGSDNDPSILIWDLRNANTPLQTLNQGHQKGILSLDWCHQDEHLLLSSGRDNTVLLWNPESAEQLSQFPARGNWCFKTKFAPEAPDLFACASFDNKIEVQTLQNLTNTLDEQETETKQQESETDFWNNVSREESKEKPTVFHLQAPTWYGEPSPAAHWAFGGKLVQITPDGKGVSITNPKISGLESNTTLSEALKTKDFKPLINQRLVKVIDDVNEEDWNLLEKLSMDGTEEFLKEALAFDNDESDAQDDANNEKEDDGEEFFQQIETNFQPEGDFSLSGNIEQTISKNLVSGNIKSAVKNSLENDLLMEAMVIALDSNNERLKESVKNAYFAKYGSKSSLSRILYSISKREVDDLVENLDVSQWKFISKAIQNLYPNDIAQRNEMLIKLGDRLKENGHRQDSLTLYLAAGSLDKVASIWLSEFPDLEDKLKKDNKTIYEAHSECLTEFIERFTVFSNFINGSSTINNEQLIAKFLEFINLTTSTGNFELATEFLNSLPSDNEEVKTEKARVLIASGKSLPAQNPATATTSKAKYTNAKTNKNVPVLPTPGMPSTTSIPSMQAPFYGMTPGASANALPPKPYVPATTTSAPVHTEGKYAPPSQPSMASPFVNKTNSSTRLNSFAPPPNPYATATVPATNVSTTSIPQNTFAPIQPGMPIMGDYNAQSSSIPSQPPINAVSGQTPHLNRKANDGWNDLPLKVKEKPSRAKAVSVAPPNILSTPTPLNGIPANAASTMPPPPLSRAPSSVSMVSPPPLHKNSRVPSLVATSESPRASISNPYAPPQSSQQFPIGTISTANQTSNTAQVASSNPYAPPPQQRVATPLSGGVPPAPLPKASNPYAPTATTQPNGSSYPPTGPYTNNHTMTSPPPVFNKPPTGPPPISMKKRSNKLASIEQNPSQGATYPPTLSSSASPLQPSQPPTLASQVNTSAENVSHEIPADQQPIVDFLKEELARVTPLTPKEYSKQLKDCDKRLKILFYHLEKQDLLTQPTIDCLHDLVALMKEKKYKEAMVIHANIATNHAQEGGNWLTGVKRLIGIAEATLN
Protein: Integrin alpha-IIb
UniProt accession: P08514
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GP2B, ITGA2B, ITGAB
Length: 1039 residues
Disorder content (fraction disordered): 0.04908565928777671
Curated region start positions: 989, 989, 997
Curated region end positions: 1039, 1039, 1008
Curated region terms: disorder, molecular adaptor activity, disorder
Domain/feature annotations: Integrin alpha, N-terminal, Bicelle-embedded integrin alpha(iib) transmembrane segment, Integrin domains. Chain A, domain 2, ntegrin, alpha v. Chain A, domain 3, Integrin alpha cytoplasmic region, FG-GAP repeat, FG-GAP repeat, Integrin alpha Ig-like domain 1, Integrin alpha Ig-like domain 2, Integrin alpha Ig-like domain 3
Sequence:
MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEEGE
Protein: Integrin beta-3
UniProt accession: P05106
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GP3A, ITGB3
Length: 788 residues
Disorder content (fraction disordered): 0.06091370558375635
Dataset labels: Autophagy-related proteins, NDDs-related proteins
Curated region start positions: 741, 763, 765, 762, 742, 783, 777, 771, 780, 780
Curated region end positions: 788, 788, 775, 788, 788, 787, 781, 775, 783, 783
Curated region terms: disorder, disorder, protein binding, protein binding, protein binding, phosphorylation display site, phosphorylation display site, phosphorylation display site, protein binding, selective autophagy
Domain/feature annotations: von Willebrand factor, type A domain, 3.10.450.180, Laminin, ligand-binding face of the semaphorins, domain 2, Laminin, Cytochrome c1, transmembrane anchor, C-terminal, ntegrin, alpha v. Chain A, domain 3, Laminin, Integrin beta chain VWA domain, Integrin beta tail domain, EGF-like domain, Integrin beta cytoplasmic domain, Integrin plexin domain, Integrin beta epidermal growth factor like domain 1, Integrin EGF domain
Cross-references: PDB:1MK7, PDB:2L1C, PDB:2MTP
Sequence:
MRARPRPRPLWATVLALGALAGVGVGGPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGNGTFECGVCRCGPGWLGSQCECSEEDYRPSQQDECSPREGQPVCSQRGECLCGQCVCHSSDFGKITGKYCECDDFSCVRYKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQPGSYGDTCEKCPTCPDACTFKKECVECKKFDRGALHDENTCNRYCRDEIESVKELKDTGKDAVNCTYKNEDDCVVRFQYYEDSSGKSILYVVEEPECPKGPDILVVLLSVMGAILLIGLAALLIWKLLITIHDRKEFAKFEEERARAKWDTANNPLYKEATSTFTNITYRGT
Protein: Protein Nef
UniProt accession: P03404
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BH10)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: nef
Length: 206 residues
Disorder content (fraction disordered): 0.12135922330097088
Dataset labels: Viral proteins
Curated region start positions: 1
Curated region end positions: 25
Curated region terms: disorder
Domain/feature annotations: HIV 1 nef anchor domain, Nef Regulatory Factor, Negative factor, (F-Protein) or Nef
Sequence:
MGGKWSKSSVIGWPAVRERMRRAEPAADGVGAASRDLEKHGAITSSNTAANNAACAWLEAQEEEKVGFPVTPQVPLRPMTYKAAVDLSHFLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGIRYPLTFGWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRLAFHHVARELHPEYFKNC
Protein: Protein SMG7
UniProt accession: Q92540
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: C1orf16, EST1C, KIAA0250, SMG7
Length: 1137 residues
Disorder content (fraction disordered): 0.02902374670184697
Curated region start positions: 111
Curated region end positions: 143
Curated region terms: disorder
Domain/feature annotations: Est1 DNA/RNA binding domain, Telomerase activating protein Est1
Cross-references: PDB:1YA0
Sequence:
MSLQSAQYLRQAEVLKADMTDSKLGPAEVWTSRQALQDLYQKMLVTDLEYALDKKVEQDLWNHAFKNQITTLQGQAKNRANPNRSEVQANLSLFLEAASGFYTQLLQELCTVFNVDLPCRVKSSQLGIISNKQTHTSAIVKPQSSSCSYICQHCLVHLGDIARYRNQTSQAESYYRHAAQLVPSNGQPYNQLAILASSKGDHLTTIFYYCRSIAVKFPFPAASTNLQKALSKALESRDEVKTKWGVSDFIKAFIKFHGHVYLSKSLEKLSPLREKLEEQFKRLLFQKAFNSQQLVHVTVINLFQLHHLRDFSNETEQHTYSQDEQLCWTQLLALFMSFLGILCKCPLQNESQEESYNAYPLPAVKVSMDWLRLRPRVFQEAVVDERQYIWPWLISLLNSFHPHEEDLSSISATPLPEEFELQGFLALRPSFRNLDFSKGHQGITGDKEGQQRRIRQQRLISIGKWIADNQPRLIQCENEVGKLLFITEIPELILEDPSEAKENLILQETSVIESLAADGSPGLKSVLSTSRNLSNNCDTGEKPVVTFKENIKTREVNRDQGRSFPPKEVRRDYSKGITVTKNDGKKDNNKRKTETKKCTLEKLQETGKQNVAVQVKSQTELRKTPVSEARKTPVTQTPTQASNSQFIPIHHPGAFPPLPSRPGFPPPTYVIPPPVAFSMGSGYTFPAGVSVPGTFLQPTAHSPAGNQVQAGKQSHIPYSQQRPSGPGPMNQGPQQSQPPSQQPLTSLPAQPTAQSTSQLQVQALTQQQQSPTKAVPALGKSPPHHSGFQQYQQADASKQLWNPPQVQGPLGKIMPVKQPYYLQTQDPIKLFEPSLQPPVMQQQPLEKKMKPFPMEPYNHNPSEVKVPEFYWDSSYSMADNRSVMAQQANIDRRGKRSPGVFRPEQDPVPRMPFEKSLLEKPSELMSHSSSFLSLTGFSLNQERYPNNSMFNEVYGKNLTSSSKAELSPSMAPQETSLYSLFEGTPWSPSLPASSDHSTPASQSPHSSNPSSLPSSPPTHNHNSVPFSNFGPIGTPDNRDRRTADRWKTDKPAMGGFGIDYLSATSSSESSWHQASTPSGTWTGHGPSMEDSSAVLMESLKSIWSSSMMHPGPSALEQLLMQQKQKQQRGQGTMNPPH
Protein: Peptidyl-prolyl cis-trans isomerase FKBP5
UniProt accession: Q13451
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AIG6, FKBP5, FKBP51
Length: 457 residues
Disorder content (fraction disordered): 0.0262582056892779
Curated region start positions: 1
Curated region end positions: 12
Curated region terms: disorder
Domain/feature annotations: Tetratricopeptide repeat domain, 3.10.50.40, 3.10.50.40, FKBP-type peptidyl-prolyl cis-trans isomerase, FKBP-type peptidyl-prolyl cis-trans isomerase, Tetratricopeptide repeat, Tetratricopeptide repeat
Cross-references: PDB:3O5E
Sequence:
MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV