Protein: DNA-directed RNA polymerase II subunit RPB1
UniProt accession: P24928
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: POLR2, POLR2A
Length: 1970 residues
Disorder content (fraction disordered): 0.10050761421319795
Dataset labels: NDDs-related proteins, Condensates-related proteins, RNA-binding proteins
Curated region start positions: 1773, 1773, 1773
Curated region end positions: 1970, 1970, 1960
Curated region terms: disorder, microfibril binding, microfibril binding
Domain/feature annotations: 3.30.1360.140, RNA polymerase Rpb1, domain 3, 1.10.132.30, RNA polymerase II, clamp domain, 1.10.150.390, 2.40.40.20, RNA polymerase ii, RNA polymerase II, clamp domain, RNA polymerase Rpb1, domain 2, RNA polymerase Rpb1, domain 3, RNA polymerase Rpb1, domain 7, RNA polymerase Rpb1, domain 6, RNA polymerase Rpb1, domain 1, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 5, RNA polymerase Rpb1, domain 4, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat, RNA polymerase Rpb1 C-terminal repeat
Sequence:
MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN