LiteFold/DisProt huggingface dataset:
Protein: Inhibin beta A chain
UniProt accession: P08476
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: INHBA
Length: 426 residues
Disorder content (fraction disordered): 0.06572769953051644
Dataset labels: Extracellular matrix proteins
Curated region start positions: 359
Curated region end positions: 386
Curated region terms: disorder
Domain/feature annotations: Cystine-knot cytokines, 2.60.120.970, Transforming growth factor beta like domain, TGF-beta propeptide
Cross-references: pdb:1nyu
Sequence:
MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGTARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Protein: Mast/stem cell growth factor receptor Kit
UniProt accession: P10721
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIT, SCFR
Length: 976 residues
Disorder content (fraction disordered): 0.022540983606557374
Dataset labels: Cancer-related proteins
Curated region start positions: 544
Curated region end positions: 565
Curated region terms: disorder
Domain/feature annotations: Immunoglobulins, Immunoglobulins, Immunoglobulins, Immunoglobulins, Immunoglobulins, Transferase(Phosphotransferase) domain 1, Phosphorylase Kinase; domain 1, Immunoglobulin domain, Protein tyrosine and serine/threonine kinase
Cross-references: PDB:1PKG
Sequence:
MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV
Protein: Coilin
UniProt accession: Q8RWK8
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At1g13030, COIL, F3F19.5
Length: 608 residues
Disorder content (fraction disordered): 0.6430921052631579
Dataset labels: RNA-binding proteins
Curated region start positions: 117, 117, 212, 212, 212, 350, 511
Curated region end positions: 350, 350, 350, 350, 350, 409, 608
Curated region terms: disorder, disorder, U2 snRNA binding, U1 snRNA binding, RNA binding, disorder, disorder
Domain/feature annotations: Coilin N-terminus, Coilin, C-terminal Tudor domain
Sequence:
MEEEKVRVRLVFEDRRILSKYQKKQGLTRSWVVLNRKCHRTISEFSDHIFHTFSLCEACPHGLSLSMEGFVLPPFESSCVLKDKDIVCVKKKKESLLEIVGEDSDENVYNAIEVEERPQIRPGEMLLANEEFQKETGGYESESEEDELEEEAEEFVPEKKASKKRKTSSKNQSTKRKKCKLDTTEESPDERENTAVVSNVVKKKKKKKSLDVQSANNDEQNNDSTKPMTKSKRSSQQEESKEHNDLCQLSAETKKTPSRSARRKKAKRQWLREKTKLEKEELLQTQLVVAPSQKPVITIDHQATKEKHCETLENQQAEEVSDGFGDEVVPVEVRPGHIRFKPLAGTDEASLDSEPLVENVLWNGNMTKKKGQKWGTEKSGFSKRYAQDFNEDATTQPAEAETLANCPIDYEQLVAYTGSVKKGDVIAYRLIELTSSWTPEVSSFRVGKISYYDPDSKMVTLMPVQEFPIEKKTEEDDDFCMQPDTSLYKEDGSLEIEFSALLDVRSVKTSSSDSAEVAKSALPEPDQSAKKPKLSANKELQTPAKENGEVSPWEELSEALSAKKAALSQANNGWNKKGSSSGGSWSYKALRGSAMGPVMNYLRSQKEI
Protein: Ubiquitin-like modifier-activating enzyme ATG7
UniProt accession: P38862
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: APG7, ATG7, CVT2, YHR171W
Length: 630 residues
Disorder content (fraction disordered): 0.02063492063492063
Dataset labels: Autophagy-related proteins
Curated region start positions: 618, 618
Curated region end positions: 630, 630
Curated region terms: disorder, protein binding
Domain/feature annotations: Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain, Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain, NAD(P)-binding Rossmann-like Domain, ThiF family, Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
Sequence:
MSSERVLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLTNRSFEKHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALECWEDGIKDINKCVSFVIISFADLKKYRFYYWLGVPCFQRPSSTVLHVRPEPSLKGLFSKCQKWFDVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLIDFKLLIIRQNEGSFALNATFASIDPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSLLDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQALYNFEDCGKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEEAQHKDFDRLRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQSSKQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQTKYSGSETTVLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKVIEAFTDLGWEFVKKALEHPLYLEEISGLSVIKQEVERLGNDVFEWEDDESDEIA
Protein: Tubulin alpha-1B chain
UniProt accession: P68363
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: TUBA1B
Length: 451 residues
Disorder content (fraction disordered): 0.07095343680709534
Curated region start positions: 416, 416
Curated region end positions: 447, 447
Curated region terms: disorder, protein binding
Domain/feature annotations: Tubulin/FtsZ, C-terminal domain, Tubulin/FtsZ, GTPase domain, Helix hairpin bin, Tubulin/FtsZ family, GTPase domain, Tubulin C-terminal domain
Cross-references: pdb:2e4h
Sequence:
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
Protein: Enhancer of mRNA-decapping protein 3
UniProt accession: Q96F86
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: EDC3, LSM16, PP844, YJDC, YJEFN2
Length: 508 residues
Disorder content (fraction disordered): 0.11023622047244094
Curated region start positions: 203, 203, 203, 203
Curated region end positions: 258, 258, 258, 258
Curated region terms: disorder, protein binding, disorder, protein binding
Domain/feature annotations: YjeF N-terminal domain, 2.30.30.100, YjeF-related protein N-terminus, FDF domain, Scd6-like Sm domain, Linker region of enhancer of mRNA-decapping protein 3
Cross-references: PDB:2WAX, PDB:2WAY, PDB:3D3J, imex:IM-23318-24635
Sequence:
MATDWLGSIVSINCGDSLGVYQGRVSAVDQVSQTISLTRPFHNGVKCLVPEVTFRAGDITELKILEIPGPGDNQHFGDLHQTELGPSGAGCQVGINQNGTGKFVKKPASSSSAPQNIPKRTDVKSQDVAVSPQQQQCSKSYVDRHMESLSQSKSFRRRHNSWSSSSRHPNQATPKKSGLKNGQMKNKDDECFGDDIEEIPDTDFDFEGNLALFDKAAVFEEIDTYERRSGTRSRGIPNERPTRYRHDENILESEPIVYRRIIVPHNVSKEFCTDSGLVVPSISYELHKKLLSVAEKHGLTLERRLEMTGVCASQMALTLLGGPNRLNPKNVHQRPTVALLCGPHVKGAQGISCGRHLANHDVQVILFLPNFVKMLESITNELSLFSKTQGQQVSSLKDLPTSPVDLVINCLDCPENVFLRDQPWYKAAVAWANQNRAPVLSIDPPVHEVEQGIDAKWSLALGLPLPLGEHAGRIYLCDIGIPQQVFQEVGINYHSPFGCKFVIPLHSA
Protein: Neutrophil cytosol factor 1
UniProt accession: P14598
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NCF1, NOXO2, SH3PXD1A
Length: 390 residues
Disorder content (fraction disordered): 0.25384615384615383
Curated region start positions: 213, 213, 296, 296, 296, 296, 296, 343, 343, 343, 213, 343
Curated region end positions: 228, 228, 330, 330, 330, 330, 304, 390, 390, 390, 228, 390
Curated region terms: disorder, disorder, disorder, disorder to order, protein binding, protein binding, protein binding, disorder, protein binding, protein binding, flexible linker, flexible C-terminal tail
Domain/feature annotations: Phox-like domain, SH3 Domains, SH3 Domains, SH3 domain, SH3 domain, PX domain, NADPH oxidase subunit p47Phox, C terminal domain, Neutrophil cytosol factor 1, PBR/AIR
Cross-references: PDB:1NG2, PDB:1WLP
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
Protein: Protein E6
UniProt accession: P26554
Organism: Human papillomavirus type 51
Taxonomy: Viruses, Monodnaviria, Shotokuvirae, Cossaviricota, Papovaviricetes, Zurhausenvirales, Papillomaviridae, Firstpapillomavirinae, Alphapapillomavirus
Gene names: E6
Length: 151 residues
Disorder content (fraction disordered): 0.0728476821192053
Dataset labels: Viral proteins
Curated region start positions: 141, 141, 141, 141, 141
Curated region end positions: 151, 151, 151, 151, 151
Curated region terms: disorder, disorder to order, protein binding, protein binding, regulation of proteolysis
Domain/feature annotations: E6 early regulatory protein, E6 early regulatory protein, Early Protein (E6)
Cross-references: BMRB:18967, PDB:2M3L, PDB:2M3M
Sequence:
MFEDKRERPRTLHELCEALNVSMHNIQVVCVYCKKELCRADVYNVAFTEIKIVYRDNNPYAVCKQCLLFYSKIREYRRYSRSVYGTTLEAITKKSLYDLSIRCHRCQRPLGPEEKQKLVDEKKRFHEIAGRWTGQCANCWQRTRQRNETQV
Protein: Methionine-R-sulfoxide reductase B1
UniProt accession: Q9JLC3
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Msrb1, Sepr, Sepx1
Length: 116 residues
Disorder content (fraction disordered): 0.3793103448275862
Curated region start positions: 1, 31, 105
Curated region end positions: 18, 44, 116
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Peptide methionine sulfoxide reductase., SelR domain
Cross-references: PDB:2KV1
Sequence:
MSFCSFFGGEVFQNHFEPGVYVCAKCSYELFSSHSKYAHSSPWPAFTETIHPDSVTKCPEKNRPEALKVSCGKCGNGLGHEFLNDGPKRGQSRFUIFSSSLKFVPKGKEAAASQGH
Protein: Capsid assembly scaffolding protein
UniProt accession: P13848
Organism: Bacillus phage phi29
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Uroviricota, Caudoviricetes, Caudovirales, Podoviridae, Picovirinae, Salasvirus
Gene names: 7
Length: 98 residues
Disorder content (fraction disordered): 0.20408163265306123
Dataset labels: Viral proteins
Curated region start positions: 79, 80, 79
Curated region end positions: 98, 98, 98
Curated region terms: flexible C-terminal tail, virion assembly, disorder
Domain/feature annotations: 1.20.5.400, Phi29 scaffolding protein
Cross-references: PDB:1NO4, PDB:1NOH
Sequence:
MPLKPEEHEDILNKLLDPELAQSERTEALQQLRVNYGSFVSEYNDLTKSHEKLAAEKDDLIVSNSKLFRQIGLTDKQEEDHKKADISETITIEDLEAK
Protein: Signal transducer and activator of transcription 6
UniProt accession: P42226
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: STAT6
Length: 847 residues
Disorder content (fraction disordered): 0.03778040141676505
Dataset labels: Cancer-related proteins
Curated region start positions: 783, 783, 790, 783, 786, 786, 799, 791
Curated region end positions: 814, 814, 799, 793, 808, 790, 808, 798
Curated region terms: disorder, protein binding, disorder, disorder, disorder to order, transcription coactivator binding, transcription coactivator binding, flexible linker
Domain/feature annotations: SH2 domain, STAT transcription factor, N-terminal domain, STAT transcription factor, DNA-binding domain, EF-hand, STAT transcription factor, all-alpha domain, SH2 domain, STAT transcription factor, coiled-coil domain, STAT protein, DNA binding domain, STAT protein, protein interaction domain, STAT6 C-terminal, Signal transducer and activator of transcription, linker domain
Cross-references: PDB:5NWM, PDB:5NWX
Sequence:
MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDTVQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
Protein: Beta-arrestin-2
UniProt accession: P32120
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: ARRB2
Length: 420 residues
Disorder content (fraction disordered): 0.16666666666666666
Curated region start positions: 352, 409, 351
Curated region end positions: 390, 420, 420
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: 2.60.40.640, 2.60.40.840, Arrestin (or S-antigen), N-terminal domain, Arrestin (or S-antigen), C-terminal domain
Cross-references: EMDB:36078, EMDB:36081, PDB:8J8R, PDB:8J8V
Sequence:
MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIANYQAFPPTPNPPRPPTRLQERLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQVEQDDQVSPSSTFCKVYTITPLLSNNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIALPRPQSAATHPPTLLPSAVPETDAPVDTNLIEFETNYATDDDIVFEDFARLRLKGLKDEDYDDQFC
Protein: Ubiquitin-like protein SMT3
UniProt accession: Q12306
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: D9719.15, SMT3, YDR510W
Length: 101 residues
Disorder content (fraction disordered): 0.22772277227722773
Curated region start positions: 1
Curated region end positions: 23
Curated region terms: disorder
Domain/feature annotations: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1, Ubiquitin-2 like Rad60 SUMO-like
Cross-references: pdb:1l2n
Sequence:
MSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGATY
Protein: Humanin
UniProt accession: Q8IVG9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HN, MT-RNR2
Length: 24 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 1
Curated region end positions: 24, 24
Curated region terms: disorder, disorder
Domain/feature annotations: Humanin family
Sequence:
MAPRGFSCLLLLTSEIDLPVKRRA
Protein: NF-kappa-B essential modulator
UniProt accession: Q9Y6K9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FIP3, IKBKG, NEMO
Length: 419 residues
Disorder content (fraction disordered): 0.2553699284009546
Dataset labels: NDDs-related proteins
Curated region start positions: 252, 150, 1
Curated region end positions: 272, 192, 43
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: L1 transposable element, trimerization domain, Nemo cc2-lz domain - 1d5 darpin complex, L1 transposable element, trimerization domain, NF-kappa-B essential modulator NEMO, Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator, C2H2 type zinc-finger
Cross-references: PDB:3CL3
Sequence:
MNRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLVERLGLEKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQEYDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
Protein: Cell division protein FtsN
UniProt accession: P29131
Organism: Escherichia coli (strain K12)
Taxonomy: Bacteria, Proteobacteria, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Escherichia
Gene names: JW3904, b3933, ftsN, msgA
Length: 319 residues
Disorder content (fraction disordered): 0.3981191222570533
Curated region start positions: 68, 124, 94
Curated region end positions: 79, 215, 116
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Sporulation related repeat, SPOR domain
Cross-references: BMRB:5984, PDB:1UTA
Sequence:
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG
Protein: Amphiphysin
UniProt accession: Q7KLE5
Organism: Drosophila melanogaster
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Diptera, Brachycera, Muscomorpha, Ephydroidea, Drosophilidae, Drosophila, Sophophora
Gene names: Amp, Amph, CG8604, DAMP, Damp, Dmel\CG8604, Dmel_CG8604, amph, dAmp, dAmph, damph
Length: 602 residues
Disorder content (fraction disordered): 0.06478405315614617
Curated region start positions: 1, 1, 158, 158, 160, 1
Curated region end positions: 26, 26, 170, 170, 164, 26
Curated region terms: disorder, disorder to order, disorder, flexible linker, lipid tube assembly, lipid binding
Domain/feature annotations: Arfaptin homology (AH) domain/BAR domain, SH3 Domains, SH3 domain, BAR domain
Cross-references: PDB:1URU
Sequence:
MTENKGIMLAKSVQKHAGRAKEKILQNLGKVDRTADEIFDDHLNNFNRQQASANRLQKEFNNYIRCVRAAQAASKTLMDSVCEIYEPQWSGYDALQAQTGASESLWADFAHKLGDQVLIPLNTYTGQFPEMKKKVEKRNRKLIDYDGQRHSFQNLQANANKRKDDVKLTKGREQLEEARRTYEILNTELHDELPALYDSRILFLVTNLQTLFATEQVFHNETAKIYSELEAIVDKLATESQRGSNTLRKQTSNPIKTSSPVQSPVNKLNNANINSNYQNQITTNGGSSLANSPTSTSSSLQEPRFDSVSSTPEPRPESPAAALVSATPSSPVENGVTTKSLERPELSGLNASAKATTTTQTSPTEDKAVVSEAVKPSETEGAAVAASVTPAPPATPAQINGNNNEPSIVKEGGKQPKELPSTTSNAEAAAEAAANNGNSIEEHKQKKLGNDTTVTATETVTVTQHSVTSTDTDNIVTISDTNTDTDTKTSTGTSQKGRPVPVVNRHSVNNLNKNPFEDDDERIYEVPADANTADLPPGVLYRVKATYGYAKEDVDELSFEIGDLIRVIEYDDPEDQEEGWLMGQKEGTNEKGLFPANFTRPI
Protein: COP9 signalosome complex subunit 5
UniProt accession: Q92905
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: COPS5, CSN5, JAB1
Length: 334 residues
Disorder content (fraction disordered): 0.09880239520958084
Curated region start positions: 198, 284
Curated region end positions: 218, 295
Curated region terms: disorder, disorder
Domain/feature annotations: Cytidine Deaminase, domain 2, JAB1/Mov34/MPN/PAD-1 ubiquitin protease, Cop9 signalosome subunit 5 C-terminal domain
Cross-references: PDB:4D10, PDB:4D18, PDB:4F7O
Sequence:
MAASGSGMAQKTWELANNMQEAQSIDEIYKYDKKQQQEILAAKPWTKDHHYFKYCKISALALLKMVMHARSGGNLEVMGLMLGKVDGETMIIMDSFALPVEGTETRVNAQAAAYEYMAAYIENAKQVGRLENAIGWYHSHPGYGCWLSGIDVSTQMLNQQFQEPFVAVVIDPTRTISAGKVNLGAFRTYPKGYKPPDEGPSEYQTIPLNKIEDFGVHCKQYYALEVSYFKSSLDRKLLELLWNKYWVNTLSSSSLLTNADYTTGQVFDLSEKLEQSEAQLGRGSFMLGLETHDRKSEDKLAKATRDSCKTTIEAIHGLMSQVIKDKLFNQINIS
Protein: Tegument protein VP16
UniProt accession: P04486
Organism: Human herpesvirus 1 (strain F)
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Peploviricota, Herviviricetes, Herpesvirales, Herpesviridae, Alphaherpesvirinae, Simplexvirus
Gene names: UL48
Length: 490 residues
Disorder content (fraction disordered): 0.2714285714285714
Dataset labels: Viral proteins
Curated region start positions: 412, 456, 456, 456, 412, 456, 456, 412, 412, 454, 412, 412, 469, 452, 475, 469, 452, 469, 452, 475, 469, 452, 350, 403
Curated region end positions: 490, 490, 490, 490, 456, 490, 490, 490, 490, 490, 490, 490, 485, 490, 484, 485, 490, 485, 490, 484, 485, 490, 394, 490
Curated region terms: disorder, disorder, molecular adaptor activity, protein binding, protein binding, protein binding, molecular function activator activity, molecular function activator activity, disorder to order, protein binding, protein binding, molecular function activator activity, disorder, disorder, disorder to order, disorder to order, disorder to order, protein binding, protein binding, molecular function activator activity, molecular function activator activity, molecular function activator activity, disorder, disorder
Domain/feature annotations: Alpha trans-inducing (Alpha-TIF), Alpha trans-inducing protein (Alpha-TIF), Herpes simplex virus virion protein 16 C terminal
Cross-references: BMRB:6099, DisProt:DP01642r001, DisProt:DP01642r002, DisProt:DP01642r005, DisProt:DP01642r006, DisProt:DP01642r007, DisProt:DP01642r009, DisProt:DP01642r010, DisProt:DP01642r014, DisProt:DP01642r015, DisProt:DP01642r016, DisProt:DP01642r017, DisProt:DP01642r018, DisProt:DP01642r019, DisProt:DP01642r026, DisProt:DP01642r027, DisProt:DP01642r028, DisProt:DP01642r029, DisProt:DP01642r030, PDB:2K2U, PDB:2PHE, PDB:2PHG, PDB:PDB:2PHE, PDB:PDB:2PHG
Sequence:
MDLLVDELFADMDADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERAQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG