LiteFold/DisProt huggingface dataset:
Protein: Mitogen-activated protein kinase 10
UniProt accession: P53779
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: JNK3, JNK3A, MAPK10, PRKM10, SAPK1B
Length: 464 residues
Disorder content (fraction disordered): 0.05603448275862069
Curated region start positions: 206
Curated region end positions: 231
Curated region terms: disorder
Domain/feature annotations: Phosphorylase Kinase; domain 1, Transferase(Phosphotransferase) domain 1, Protein kinase domain
Cross-references: PDB:1JNK
Sequence:
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAVNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
Protein: Vitellogenin
UniProt accession: C4PB33
Organism: Bombus ignitus
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Hymenoptera, Apocrita, Aculeata, Apoidea, Apidae, Bombus, Bombus
Length: 1772 residues
Disorder content (fraction disordered): 0.019751693002257337
Curated region start positions: 361
Curated region end positions: 395
Curated region terms: disorder
Domain/feature annotations: Lipovitellin; beta-sheet shell regions, chain A, Vitellinogen, superhelical, von Willebrand factor type D domain, Lipoprotein amino terminal region, Vitellinogen, open beta-sheet
Sequence:
MWLPLTVLLLAGIVSADYDHGWHVNNEYIYLVRSRTLVNLNELSDQHTGILMKALLTIQVKDPQMLTAKVSQSQYARILKSLPEGWDAEISDQMLELRDMPLSGKPFNIKLKHGVIRDIIVDRTIPTWEVNILKSIVSQLQVDSLGENAIRTSEMQIPTDEHPYGMFRAMEDSVGGKCEVLYDITPLPEQNVYVQPELVPVPDLKREGQYIDIRKSKNFNKCDQRMNYQFGITGNKYWEAGSNKNGKFFSQSAMSRIIISGTLKSYTIQSAVTTNIMYISPRFYDHEHGMVTSRMNLTLAAVKKITNPLPKPNSPESTGNLVYIYSNPYSDMEERRVGKVVEDSDNMMLSDSISSISSSEEATKGQNYRSLSSDSSSSSSFSNSEEDHYWQPKPTMEDAPQNPLSSIYIGYMGKYIGKSNEVDVVEKSKELISQIANEMEDPNDVYENHILEKYTVLCNLLRTMNKEQMLQVDKHVRLSPHELKSMDKTQVLKQNAWTVLKSAVAQAGTGPAFLVIKNWIEMKEVDSKRGADLLAKLPKTARAPTAEYIMEFFKLATGETVKNDLALNSSAIIAFSELVYNAQVSRKGLHNHYPVHTYGRLTPKHNKAVTEYYIPYLETELKKAVESGQSTVIQTYIMALGNIGHPKILPVLEPYLEGKVRMTVFQRTLMVSTLAKLAENFPKLARSILYKIYLNTMEEHQVRCTAVFILMQTDPPLTMLQRMAEFTKIDKNKYVNSAVKSTLESLANLKDAEYQTLAKKARVAKNLLSPSDYSYHYSRGYITESIMDEGNIISHMMLKYIGSDDSLIPNAIYYAVFSTYGDFKLPPFEVVTMVSSIRSILELNTSPEEKERIKLAAEKIAEQLNIISDEFIPLEGNIMWNGKYGARFLPFDQSCLSLLRELLLMYLKGESEGKLINRLGSYDITYGFPTETGLPFVYNFELPMLLKITGAMNNEAKNLKTIKMKTDFRILYAMKIQGRMSFVTPFEHQEYIAGVDVDFNLHLPMKLTLDIDLPKQSFEIKIWPLKGEDKAQLLHYSVVPYVANHNILSLRPLLTEKTAQMIIPDDIYLDTISDSDLLKVVLETDKSYDYKNWLDLDIDDLFNVVIAPWSSDNDNYRKVDVFLNLKREQVAPFVLKMSYDFMEMAPTAEDAKLWTPKATAMEPSDKHPDSEVRRKQWMDEAAKGVKSAKSQVIDIRLEVPVTSEETIMNVITVATSNSEIEKKGRTLVYWNFETLFEVCAASQTKVTPDNTVFYEEVAQLKPKVEFNADFRIGKVCSTGEQLNINSVATQSKELRERIKNSSLIKTCEKQMQQGNKILRACQNAAAISMILDQITISVDFQSQHFINFITKALNVMMNIDYLNEIAYIHTELSDLKVAGKRKIDIVANLTNDFESADVLISTPNMNIYANDIDLSALEISAEDVLMAADEDMDIQNLLYNEDEPACILDKTRAQTFDSKEYPLRLGKCWHVVVTTYPRVNPNNPNEKMRMHKFDSVSILTRDMENGQREMKVLLGDKELKFVPTSSQPKIFVNEQLIKVTKDMSWQEKMDDEVLYEIFQINDHSVGLVSDEYELNLVYDGKRIMMKAGDKFRKAIRGLCGNYDGKLINDFMAPEKCVFRKPEQFIASYALTKEECESEFFENSKLLMDQDCVYEEKNHLSNVISDKESGRRDIEESNWGYHKQTKSKQCTIMKAHMKEIEHMICFTIRQVPSCAPGCWATEMKPKDYQYHCMKRNAASLALKARIEKGAKPDLSQKSVTLTEPINVPLACKA
Protein: Vitellogenin
UniProt accession: O17428
Organism: Pimpla nipponica
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Arthropoda, Hexapoda, Insecta, Pterygota, Neoptera, Endopterygota, Hymenoptera, Apocrita, Parasitoida, Ichneumonoidea, Ichneumonidae, Pimplinae, Pimplini, Pimpla
Gene names: Vg
Length: 1807 residues
Disorder content (fraction disordered): 0.02324294410625346
Curated region start positions: 356
Curated region end positions: 397
Curated region terms: disorder
Domain/feature annotations: Vitellinogen, superhelical, Lipovitellin; beta-sheet shell regions, chain A, von Willebrand factor type D domain, Lipoprotein amino terminal region, Vitellinogen, open beta-sheet
Sequence:
MWCPLFLVLLAGAATAEHLQAWKTDTEYQYAVRGRTLSALHDVADQYSGIIMRALLTIQPKSDGTLEAKVTKARYAQIHTKLPGGWNSEIPDHKLEMKQFPMSEKVFEIKMKHGVVRDLIVDKDVPTWEVNVLKSIVSQLQVDTQGENLMASKYNQEPEDEGVTAMFKTMEDTVGGRCEVLYDINPLPEFVLQKRPELVPMPDIRGDGEIIDIVKTKNYSNCEQRSGYHFGIPGTNKWEPSSGASGNFLSRSSVSRVIVTGNLKSFTIQSSVSTNKVILSPNFHENRKGMVSSRVNVTLVKIGAPSTGDWSTPANPESTGNLVYNYNNPFAGVGEDRRASRPQDNRNSEEKVRSLYNLYRRNRINDNDDDSSASDSSKSAKSLESNEEQLYWQPKPTLNEAPAMAMLPFFIGNHGKSIHKTDEIEPITMAKTLASQIGSDFQDPNSITDEQTLEKFTLLVRIIRTMSTQQIAEAERDLYQSNNEIDPHDESQSVRRGTWAAFRDAVAQAGTAPALVTITLWIKQKKIRGVEAASVVGVLAKTARTPTREYIDVFFELATMPETIHEPFLNTTALFTFSELVRYSQMDNPSSHTRYPVHTFGRFSDKINPEVFRMYVPYLAEKLKTSIEKNENAKAHTYIVSLGNIAHPKILAVFEPYLEGKMPASTFQRLLMVISLNKLATLKPKLARGVFYRIYKNTGEAHQLRCAAVTALMSTNPPASMLQRMAEFTNEDHSKHVNAAVKSAIESASELETPQWQELAENARNAKPLLNKESYGFEYSKLYLTDFIEREMNVAYQAQASFISSDDSYVPEALFVKARAIFGGFTFPRTSAGAMVSSAKDLLSAFEDAFKGEKTSHKHSHVEFSPENVAKLLKIKSEPNEDVEGAFMLQSAYNNKFMSLDKNTLKNLPELSSKALKALKDGHHFNTARIESYEMTMSFPMESGFPFVYTMKVPSMLKLAGSVKGDSNEDSLDGHVHLRAVYSVQFQSKLGFVTPFEHQHYMAGINKNYQAYVPLRVNVNYEDSDKRVTLKIQPIEQNEKFKLWHHSVVPFTSRHDILKMSPVLKDKETQKIITEEVSKNEYNFGSDKHGVKFTVLAEADNDNSPLNFEDAKWERNPLTQLFHLFVEQPVYHKVDIFMQPSKSSEQSIILSTAFETLQDDTTKYDEDRSKHIKAEAPKVENKKLNDPQRRRKLLKEAAKGIAAADAFAVDIGLEYPGQAPVQAFATLAFASSEVDEKSRGLVYWRLTDAGNDFEFESCTSLEARSPRTSDFGKDMLDQPEFRSRKFDIDLRYGQTCEKGYKVEIQGSQEQTEKYRDTIKRLPTAIECIRAAKKGMKSLPACHDVSVKMTMLDKTRITIKYDKDSREMYQLFDDYLDSMSDADDDLKSSKKRLNAVKDDDKAYDDTVKIAVDLSPNDNNGRFSYESDFVKLEARDVPINGIGPLVNVHPDLETAERLDMDMSDEPVRQRICVLDSHSATTFDESTYPINLGKCWHVVMTTFPKTNKNSGSAEPIDEDMALSILVRDAGDKKKDIKVTLGDKELQFSHADSKNKVTLDGKKVDLSEKRSYRHKNGKDIDFEVLQRPDGTLGLVSSKYDIDAWYDGQRVQIKASGKYRSDIRGLCGNFDGEPDNDFTSPKDCVLLKPEEFAASYALTTKDCHGSALEHARKASQAVCSQKSPRPGNVVSDRDAGRKYSENSNWGYHSRQNSDDEQGKNDSSDHKRCNTLRTKVIEEEDQICFSLRPLPTCAEGCTANRTKPKVMPMHCMPKNIAAERMADRIKQGANPDFSQKSYTKKNGFDIPVGCHAA
Protein: cAMP-dependent protein kinase type II-alpha regulatory subunit
UniProt accession: P13861
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PKR2, PRKAR2, PRKAR2A
Length: 404 residues
Disorder content (fraction disordered): 0.11633663366336634
Curated region start positions: 44, 44
Curated region end positions: 90, 90
Curated region terms: disorder, flexible linker
Domain/feature annotations: Jelly Rolls, Jelly Rolls, cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain, Cyclic nucleotide-binding domain, Cyclic nucleotide-binding domain, Regulatory subunit of type II PKA R-subunit
Sequence:
MSHIQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARAPASVLPAATPRQSLGHPPPEPGPDRVADAKGDSESEEDEDLEVPVPSRFNRRVSVCAETYNPDEEEEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVSERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIARCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSSVDLGNLGQ
Protein: Kaposi's sarcoma-associated herpes-like virus ORF73 homolog
UniProt accession: Q98148
Organism: Human herpesvirus 8
Taxonomy: Viruses, Duplodnaviria, Heunggongvirae, Peploviricota, Herviviricetes, Herpesvirales, Herpesviridae, Gammaherpesvirinae, Rhadinovirus
Length: 1162 residues
Disorder content (fraction disordered): 0.3786574870912221
Dataset labels: Viral proteins
Curated region start positions: 1110, 1133, 1133, 745, 620, 325, 1133
Curated region end positions: 1162, 1144, 1144, 925, 723, 426, 1144
Curated region terms: disorder, disorder to order, protein binding, disorder, disorder, disorder, viral life cycle
Domain/feature annotations: Epstein Barr virus nuclear antigen-1, DNA-binding domain, Protein LANA1-like, DNA-binding domain
Cross-references: BMRB:26042, PDB:2ND0
Sequence:
MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSIDGRECGPHTLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPVSPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPPEPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWATESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKECSENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEEDEEDDDDEDNEDEEDDEEEDKKEDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPLQEPQQQEPQQQEPLQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQREPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQEQQDEQEQQDEQEQQDEQQQDEQQQQDEQQQQDEQQQQDEQQQQDEQQQQDEQEQQEEQEQQEEQEQELEEQEQELEDQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEVEEQEQEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQELEEVEEQEQQELEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDDDPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARPQHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGPDQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQGPGDSPQEMT
Protein: Supervillin
UniProt accession: O46385
Organism: Bos taurus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Laurasiatheria, Artiodactyla, Ruminantia, Pecora, Bovidae, Bovinae, Bos
Gene names: SVIL
Length: 2194 residues
Disorder content (fraction disordered): 0.15587967183226983
Curated region start positions: 1, 11, 11, 1
Curated region end positions: 342, 174, 174, 342
Curated region terms: disorder, protein binding, protein binding, molecular adaptor activity
Domain/feature annotations: Severin, Severin, Villin headpiece domain, Severin, Severin, Severin, Gelsolin repeat, Villin headpiece domain
Sequence:
MKRKERIARRLEGIETDTQPILLQSCTGLVTHRLLEEDTPRYMRATDPASPHIGRSNEEEETSDSSLEKQTRSKQCTETSGIHADSPYSSGIMDTQSLESKAERIARYKAERRRQLAEKYGLTLDPEADSETPSRYSRSRKDPEAAEKRGVRSERSAESSRDAGSSYSRTELSGLRTCVAESKDYGLHRSDGVSDTEVLLNAENQRRGQEPSATGLARDLPLAGEVSSSFSFSGRDSALGEVPRSPKAVHSLPSPSPGQPASPSHSTSDLPLPAEARASIGKPKHEWFLQKDSEGDTPSLINWPSRVKVREKLVREESARSSPELTSESLTQRRHQTAPGHYLAFQSENSAFDRVSGKVASSARQPIRGYVQPAEPVHTITLVTSDTPESISEGSWVGPAPQTVTKPPPSKVLEGERRDTPVLHICESKAEDVLFSDALEKTRKTLAVLEDRGSGRSQEAPSGTEDLSQPAVGIVTAEPQKESESLAHPPMAQQQPTERMGRSEMVMYVQSEAVSQGHRKEVPTRKHRVLTRSLSDYTGPPQLQALKAKAPAPKRDAESQTSKAELELGLLDTKVSVAQLRNAFLESARASRKPELHSRVEGSSEGPGVERERGSRKPRRYFSPGENRKTSERFRTQPITSAERKESDRSTSNSEMPAAEDEEKVDERARLSVAAKRLLFREMEKSFDEKSVPKRRSRNAAVEQRLRRLQDRSHTQPVTTEEVVIAAEPTPASCSVATHPVMTRHPSPTVAKSPVQPARTLQASAHQKALARDQTNESKDSAEQGEPDSSTLSLAEKLALFNKLSQPVSKAISTRNRLDMRQRRMNARYQTQPVTLGEVEQVQSGKLMAFSPTINTSVSTVASTVPPMYAGNLRTKPLPDDSFGATEQKFASSLENSDSPVRSILKSQGWQPSVEGAGSKAMLREFEETERKGGLTGGDGGVTKYGSFEEAELSYPVLSRVREGDNHKEAIYALPRKGSLELAHPPIAQLGDDLKEFSTPKSTMQASPDWKERQLFEEKVDLENVTKRKFSLKAAEFGEPTSEQTGAAAGKPAAPTATPVSWKPQDPSEQPQEKRYQSPCAMFAAGEIKAPAVEGSLDSPSKTMSIKERLALLKKSGEEDWRNRLNRKQEYGKASITSSLHIQETEQSLKKKRVTESRESQMTIEERKHLITVREDAWKTRGKGAANDSTQFTVAGRMVKRGLASPTAITPVASPVSSKARGTTPVSRPLEDIEARPDMQLESDLKLDRLETFLRRLNNKVGGMQETVLTVTGKSVKEVMKPDDDETFAKFYRSVDSSLPRSPVELDEDFDVIFDPYAPRLTSSVAEHKRAVRPKRRVQASKNPLKMLAAREDLLQEYTEQRLNVAFVESKRMKVEKLSANSSFSEVTLAGLASKENFSNVSLRSVNLTEQNSNNSAVPYKKLMLLQVKGRRHVQTRLVEPRAPSLNSGDCFLLLSPHHCFLWVGEFANVIEKAKASELASLIQTKRELGCRATYIQTVEEGINTHTHAAKDFWKLLGGQASYQSAGDPKEDELYETAIIETNCIYRLMDDKLVPDDDYWGKIPKCSLLQSKEVLVFDFGSEVYVWHGKEVTLAQRKIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFKEKFLDWTELKRPNEKNASELAQHKDDARAEVKPYDVTRMVPVPQTTAGTVLDGVNVGRGYGLVEGDDRRQFEIASISVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFIVSTAVGSRQKGEHSVRVAGKEKCVYFFWQGRQSTVSEKGTSALMTVELDEERGAQVQVLQGKEPPCFLQCFQGGMVVHSGRREEEEENTQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVHKALIYLWHGCKAQAHTKEVGRTAANKIKDQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRRDRKAYDCMLQDPGNFNFTPRLFILSSSSGDFSATEFMYPARDPSVVNSMPFLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCRGKNLKKPPPKSYLIHAGLEPLTFTNMFPSWEHREDIAEITEMDTEVSNQITLVEDVLAKLCKTIYPLADLLARPLPEGVDPLKLEIYLTDEDFEFALDMTRDEYNALPAWKQVNLKKAKGLF
Protein: UDP-glucose 6-dehydrogenase
UniProt accession: O60701
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: UGDH
Length: 494 residues
Disorder content (fraction disordered): 0.06072874493927125
Dataset labels: NDDs-related proteins
Curated region start positions: 465, 465
Curated region end positions: 494, 494
Curated region terms: flexible C-terminal tail, disorder
Domain/feature annotations: NAD(P)-binding Rossmann-like Domain, NAD(P)-binding Rossmann-like Domain, Cytochrome c1, transmembrane anchor, C-terminal, UDP-glucose/GDP-mannose dehydrogenase family, central domain, UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain, UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain
Cross-references: PDB:5VR8
Sequence:
MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDVNESRINAWNSPTLPIYEPGLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLIGGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDMFKELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIPKFSLQDPPNKKPKV
Protein: Plastid transcriptionally active 4
UniProt accession: A0A178W0D3
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At1g65260, PTAC4, T8F5.2, T8F5_2, VIPP1
Length: 259 residues
Disorder content (fraction disordered): 0.15057915057915058
Curated region start positions: 221, 221, 221
Curated region end positions: 259, 259, 259
Curated region terms: disorder, disorder, protein folding chaperone
Domain/feature annotations: PspA/IM30 family
Sequence:
MNLFERFSRVVKSYANALISSFEDPEKILEQTVIEMNSDLTKMRQATAQVLASQKQLQNKYKAAQQSSDDWYKRAQLALAKGDEDLAREALKRRKSFADNATALKTQLDQQKGVVDNLVSNTRLLESKIQEAKAKKDTLLARARTAKTATKVQEMIGTVNTSGALSAFEKMEEKVMAMESEADALTQIGTDELEGKFQMLETSSVDDDLADLKKELSGSSKKGELPPGRSTVAASTRYPFKDSEIENELNELRRKANDF
Protein: Neuromodulin
UniProt accession: P06837
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Basp2, Gap43
Length: 227 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1, 34, 34, 1, 34, 34, 34
Curated region end positions: 227, 57, 57, 227, 57, 57, 57
Curated region terms: pre-molten globule, localization, molecular function regulator, pre-molten globule, protein binding, protein binding, pre-molten globule to order
Domain/feature annotations: IQ calmodulin-binding motif, Neuromodulin, Gap junction protein N-terminal region
Cross-references: PDB:4E53
Sequence:
MLCCMRRTKQVEKNDEDQKIEQDGVKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAPAAEAEAKEKDDAPVADGVEKKEGDGSATTDAAPATSPKAEEPSKAGDAPSEEKKGEGDAAPSEEKAGSAETESAAKATTDNSPSSKAEDGPAKEEPKQADVPAAVTDAAATTPAAEDAATKAAQPPTETAESSQAEEEKDAVDEAKPKESARQDEGKEDPEADQEHA
Protein: RNA guanine-N7 methyltransferase activating subunit
UniProt accession: Q9BTL3
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: C15orf18, FAM103A1, RAMAC, RAMMET
Length: 118 residues
Disorder content (fraction disordered): 0.3728813559322034
Curated region start positions: 2, 2, 2, 2
Curated region end positions: 45, 45, 45, 45
Curated region terms: disorder, disorder to order, protein binding, molecular function activator activity
Domain/feature annotations: mRNA cap methylation, RNMT-activating mini protein
Cross-references: PDB:5E8J
Sequence:
MTDTAEAVPKFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY
Protein: NF-kappa-B-activating protein
UniProt accession: Q8N5F7
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: NKAP
Length: 415 residues
Disorder content (fraction disordered): 0.927710843373494
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 1, 359, 1, 359
Curated region end positions: 328, 328, 415, 328, 415
Curated region terms: disorder, disorder, disorder, disorder, disorder
Domain/feature annotations: NF-kappa-B-activating protein C-terminal domain, NF-kappa-B-activating protein
Cross-references: EMDB:16452, EMDB:32321, EMDB:4525, PDB:6QDV, PDB:7W5B, PDB:8C6J
Sequence:
MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEPSDLIGPEAPKTLTSQDDKPLNYGHALLPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIASFECSGYVMSGSRHRRMEAVRLRKENQIYSADEKRALASFNQEERRKRENKILASFREMVYRKTKGKDDK
Protein: AF4/FMR2 family member 1
UniProt accession: P51825
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AF4, AFF1, FEL, MLLT2, PBM1
Length: 1210 residues
Disorder content (fraction disordered): 0.019008264462809916
Dataset labels: Cancer-related proteins
Curated region start positions: 738
Curated region end positions: 760
Curated region terms: disorder
Domain/feature annotations: AF-4 proto-oncoprotein N-terminal region, AF4 interaction motif, AFF4, C-terminal homology domain
Cross-references: PDB:2LM0
Sequence:
MAAQSSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSSRIQNMLGNYEEVKEFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEPMPSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVKFDKQQADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIECGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNMAMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIASTGTPSPLSPMPSPASSVGSQSSAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLSTNVCTLALNSSLVDLVHYTRQGFQQLQELTKTP
Protein: Heat shock 70 kDa protein 1B
UniProt accession: P0DMV9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSP72, HSPA1B
Length: 641 residues
Disorder content (fraction disordered): 0.1216848673946958
Curated region start positions: 229
Curated region end positions: 306
Curated region terms: disorder
Domain/feature annotations: Substrate Binding Domain Of DNAk; Chain A, domain 1, G3DSA:1.20.1270.10, Hsp70 protein
Sequence:
MAKAAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSYKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANTLAEKDEFEHKRKELEQVCNPIISGLYQGAGGPGPGGFGAQGPKGGSGSGPTIEEVD
Protein: Pre-mRNA-splicing factor cwf15
UniProt accession: P78794
Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Taphrinomycotina, Schizosaccharomycetes, Schizosaccharomycetales, Schizosaccharomycetaceae, Schizosaccharomyces
Gene names: SPBC337.06c, cwf15
Length: 265 residues
Disorder content (fraction disordered): 0.660377358490566
Curated region start positions: 1, 71
Curated region end positions: 23, 222
Curated region terms: disorder, disorder
Domain/feature annotations: Cwf15/Cwc15 cell cycle control protein
Cross-references: PDB:3JB9
Sequence:
MTTAHRPQFDPARGHSEMAPTRITSSRALPAHLKLKYRQESQGTEEEVRKQDLREALLRAEAAHFATQEHGASSEEVSQNSKLIEGFTSPSTDDKPNNDVEVDYQELLRQTLEADEDASDSDDSVDSSNKNSEVSIKRRKTESNSQESVDSSNSESSDEESDSEDETQQLLRELENIKQERKREQMLQEEKNRALEQEKREREIAFGNELLNKASSGSFQVKRRWDEDVVFRNTHKGVDDTPRPGFVNDMLRSEFHKKFLARFVD
Protein: Complexin-1
UniProt accession: O14810
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CPLX1
Length: 134 residues
Disorder content (fraction disordered): 0.07462686567164178
Dataset labels: NDDs-related proteins
Curated region start positions: 74
Curated region end positions: 83
Curated region terms: disorder
Domain/feature annotations: Synaphin protein
Cross-references: PDB:3RK3, PDB:3RL0
Sequence:
MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQAEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAAMEANSEGSLTRPKKAIPPGCGDEVEEEDESILDTVIKYLPGPLQDMLKK
Protein: BAG family molecular chaperone regulator 4
UniProt accession: O95429
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BAG4, SODD
Length: 457 residues
Disorder content (fraction disordered): 0.0437636761487965
Curated region start positions: 357
Curated region end positions: 376
Curated region terms: disorder
Domain/feature annotations: BAG domain, BAG domain
Cross-references: PDB:1M7K
Sequence:
MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPLYPLRPEPPQPPISWRVRGGGPAETTWLGEGGGGDGYYPSGGAWPEPGRAGGSHQEQPPYPSYNSNYWNSTARSRAPYPSTYPVRPELQGQSLNSYTNGAYGPTYPPGPGANTASYSGAYYAPGYTQTSYSTEVPSTYRSSGNSPTPVSRWIYPQQDCQTEAPPLRGQVPGYPPSQNPGMTLPHYPYGDGNRSVPQSGPTVRPQEDAWASPGAYGMGGRYPWPSSAPSAPPGNLYMTESTSPWPSSGSPQSPPSPPVQQPKDSSYPYSQSDQSMNRHNFPCSVHQYESSGTVNNDDSDLLDSQVQYSAEPQLYGNATSDHPNNQDQSSSLPEECVPSDESTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL
Protein: Isoform 3 of Ran-binding protein 3
UniProt accession: Q9H6Z4-3
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RANBP3
Length: 499 residues
Disorder content (fraction disordered): 0.03006012024048096
Curated region start positions: 31
Curated region end positions: 45
Curated region terms: disorder
Cross-references: PDB:5XZX
Sequence:
MADLANEEKPAIAPPVFVFQKDKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLTQFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSESSSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSNEEDDSDDDDVLAPSGATAAGAGDEGDGQTTGST