LiteFold/DisProt huggingface dataset:
Protein: Protein transport protein TIP20
UniProt accession: P33891
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: TIP1, TIP20, YGL145W
Length: 701 residues
Disorder content (fraction disordered): 0.025677603423680456
Curated region start positions: 217
Curated region end positions: 234
Curated region terms: disorder
Domain/feature annotations: RINT-1/TIP-1 family
Cross-references: PDB:3FHN
Sequence:
MNGIDDLLNINDRIKQVQNERNELASKLQNLKQSLASNDTEVALSEVIAQDIIEVGASVEGLEQLRAKYGDLQILNKLEKVAVQQTQMQAGVDKLDSFERQLDELAEQPPDQFTLDDVKALHSKLTSVFATVPQINNIDSQYAAYNKLKSKVTGKYNDVIIQRLATNWSNTFDQKLLEAQWDTQKFASTSVGLVKCLRENSTKLYQLSLLYLPLEEETQNGDSERPLSRSNNNQEPVLWNFKSLANNFNVRFTYHFHATSSSSKIETYFQFLNDYLAENLYKCINIFHDDCNGLTKPVIHEQFINYVLQPIRDKVRSTLFQNDLKTLIVLISQILATDKNLLNSFHYHGLGLVSLISDEVWEKWINYEVEMANRQFINITKNPEDFPKSSQNFVKLINKIYDYLEPFYDLDFDLLVRYKLMTCSLIFMNLTSSYLDYILTVDSLNETRTKEQELYQTMAKLQHVNFVYRKIKSLSSNFIFIQLTDIVNSTESKKYNSLFQNVENDYEKAMSTDMQNSIVHRIQKLLKETLRNYFKISTWSTLEMSVDENIGPSSVPSAELVNSINVLRRLINKLDSMDIPLAISLKVKNELLNVIVNYFTESILKLNKFNQNGLNQFLHDFKSLSSILSLPSHATNYKCMSLHELVKILKLKYDPNNQQFLNPEYIKTGNFTSLKEAYSIKYLKDTKIQDALYRIIYGNIL
Protein: Ras GTPase-activating protein-binding protein 2
UniProt accession: Q9UN86
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: G3BP2, KIAA0660
Length: 482 residues
Disorder content (fraction disordered): 0.02074688796680498
Dataset labels: Condensates-related proteins, RNA-binding proteins
Curated region start positions: 45
Curated region end positions: 54
Curated region terms: disorder
Domain/feature annotations: RNA recognition motif, Nuclear transport factor 2 (NTF2) domain
Cross-references: PDB:5DRV
Sequence:
MVMEKPSPLLVGREFVRQYYTLLNKAPEYLHRFYGRNSSYVHGGVDASGKPQEAVYGQNDIHHKVLSLNFSECHTKIRHVDAHATLSDGVVVQVMGLLSNSGQPERKFMQTFVLAPEGSVPNKFYVHNDMFRYEDEVFGDSEPELDEESEDEVEEEQEERQPSPEPVQENANSGYYEAHPVTNGIEEPLEESSHEPEPEPESETKTEELKPQVEEKNLEELEEKSTTPPPAEPVSLPQEPPKAFSWASVTSKNLPPSGTVSSSGIPPHVKAPVSQPRVEAKPEVQSQPPRVREQRPRERPGFPPRGPRPGRGDMEQNDSDNRRIIRYPDSHQLFVGNLPHDIDENELKEFFMSFGNVVELRINTKGVGGKLPNFGFVVFDDSEPVQRILIAKPIMFRGEVRLNVEEKKTRAARERETRGGGDDRRDIRRNDRGPGGPRGIVGGGMMRDRDGRGPPPRGGMAQKLGSGRGTGQMEGRFTGQRR
Protein: HTLV-1 basic zipper factor
UniProt accession: P0C746
Organism: Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Deltaretrovirus
Gene names: HBZ
Length: 209 residues
Disorder content (fraction disordered): 0.3588516746411483
Dataset labels: Viral proteins
Curated region start positions: 3, 3, 3, 3, 33
Curated region end positions: 77, 77, 77, 77, 56
Curated region terms: disorder, disorder, protein binding, disorder to order, disorder to order
Cross-references: PDB:6DMX
Sequence:
MVNFVSAGLFRCLPVSCPEDLLVEELVDGLLSLEEELKDKEEEEAVLDGLLSLEEESRGRLRRGPPGEKAPPRGETHRDRQRRAEEKRKRKKEREKEEEKQTAEYLKRKEEEKARRRRRAEKKAADVARRKQEEQERRERKWRQGAEKAKQHSARKEKMQELGIDGYTRQLEGEVESLEAERRKLLQEKEDLMGEVNYWQGRLEAMWLQ
Protein: High affinity copper uptake protein 1
UniProt accession: O15431
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: COPT1, CTR1, SLC31A1
Length: 190 residues
Disorder content (fraction disordered): 0.2736842105263158
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 52, 52, 52, 52, 52
Curated region terms: disorder, disorder to order, flexible N-terminal tail, disorder to order, copper ion binding
Domain/feature annotations: Ctr copper transporter family
Sequence:
MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
Protein: Cytochrome P450 165B3
UniProt accession: Q8RN04
Organism: Amycolatopsis orientalis
Taxonomy: Bacteria, Actinomycetota, Pseudonocardiales, Pseudonocardiaceae, Amycolatopsis
Gene names: cyp165B3, oxyB
Length: 398 residues
Disorder content (fraction disordered): 0.032663316582914576
Curated region start positions: 70
Curated region end positions: 82
Curated region terms: disorder
Domain/feature annotations: Cytochrome P450
Cross-references: PDB:1LFK
Sequence:
MSEDDPRPLHIRRQGLDPADELLAAGALTRVTIGSGADAETHWMATAHAVVRQVMGDHQQFSTRRRWDPRDEIGGKGIFRPRELVGNLMDYDPPEHTRLRRKLTPGFTLRKMQRMAPYIEQIVNDRLDEMERAGSPADLIAFVADKVPGAVLCELVGVPRDDRDMFMKLCHGHLDASLSQKRRAALGDKFSRYLLAMIARERKEPGEGMIGAVVAEYGDDATDEELRGFCVQVMLAGDDNISGMIGLGVLAMLRHPEQIDAFRGDEQSAQRAVDELIRYLTVPYSPTPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALAPDVDRLDVTREPIPHVAFGHGVHHCLGAALARLELRTVFTELWRRFPALRLADPAQDTEFRLTTPAYGLTELMVAW
Protein: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, apicoplast
UniProt accession: P62368
Organism: Plasmodium falciparum (isolate 3D7)
Taxonomy: Eukaryota, Sar, Alveolata, Apicomplexa, Aconoidasida, Haemosporida, Plasmodiidae, Plasmodium, Plasmodium (Laverania)
Gene names: IspF, PF3D7_0209300, PFB0420w
Length: 240 residues
Disorder content (fraction disordered): 0.06666666666666667
Curated region start positions: 82
Curated region end positions: 97
Curated region terms: disorder
Domain/feature annotations: YgbB family
Cross-references: PDB:4C81, PDB:4C82
Sequence:
MFLKGYTSNVVLIILTFFILLTKEEKNIKNNISGYCFLNFGLKKNAIIKKREKQNLKLFCYNGIRIGQGYDIHKIKVLDEEYNTYANNDFNKNEQSFKTLTLGGVKINNVLVLSHSDGDIIYHSIVDSILGALGSLDIGTLFPDKDEKNKNKNSAIFLRYARLLIYKKNYDIGNVDINVIAQVPKISNIRKNIIKNISTVLNIDESQISVKGKTHEKLGVIGEKKAIECFANILLIPKNS
Protein: Leucine-rich repeat protein SHOC-2
UniProt accession: Q9UQ13
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: KIAA0862, SHOC2
Length: 582 residues
Disorder content (fraction disordered): 0.14604810996563575
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 1
Curated region end positions: 85, 85
Curated region terms: disorder, disorder
Domain/feature annotations: Leucine rich repeat, Leucine-rich repeat region, Leucine-rich repeat region
Cross-references: PDB:7SD1
Sequence:
MSSSLGKEKDSKEKDPKVPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
Protein: Dihydropyrimidinase-related protein 5
UniProt accession: Q9BPU6
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CRMP5, DPYSL5, ULIP6
Length: 564 residues
Disorder content (fraction disordered): 0.1276595744680851
Dataset labels: NDDs-related proteins
Curated region start positions: 493
Curated region end positions: 564
Curated region terms: disorder
Domain/feature annotations: Amidohydrolase family
Cross-references: PDB:4B90
Sequence:
MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW
Protein: Isoform 2 of Rap1 GTPase-GDP dissociation stimulator 1
UniProt accession: P52306-2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: RAP1GDS1, SMGGDS
Length: 558 residues
Disorder content (fraction disordered): 0.03225806451612903
Dataset labels: NDDs-related proteins
Curated region start positions: 61
Curated region end positions: 78
Curated region terms: disorder
Cross-references: PDB:5XGC
Sequence:
MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTEQRLTVES
Protein: Probable G-protein coupled receptor 158
UniProt accession: Q5T848
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GPR158, KIAA1136
Length: 1215 residues
Disorder content (fraction disordered): 0.2411522633744856
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 221, 362, 24, 221, 512, 512, 512, 669, 764, 669
Curated region end positions: 69, 260, 388, 70, 261, 524, 524, 524, 702, 863, 710
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, order, disorder to order, disorder, disorder, disorder
Domain/feature annotations: 7 transmembrane sweet-taste receptor of 3 GCPR, GPR158/179 extracellular domain
Cross-references: EMDB:31351, EMDB:31360, EMDB:31363, PDB:7EWL, PDB:7EWP, PDB:7EWR
Sequence:
MGAMAYPLLLCLLLAQLGLGAVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHPGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAIISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKEKSHHKPKAAEVCQQSNQKRIDKAEVCLWESQGQSILEDEKLLISKTPVLPERAKEENGGQPRAANVCAGQSEELPPKAVASKTENENLNQIGHQEKKTSSSEENVRGSYNSSNNFQQPLTSRAEVCPWEFETPAQPNAGRSVALPASSALSANKIAGPRKEEIWDSFKV
Protein: 14-3-3-like protein C
UniProt accession: P93343
Organism: Nicotiana tabacum
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, asterids, lamiids, Solanales, Solanaceae, Nicotianoideae, Nicotianeae, Nicotiana
Length: 260 residues
Disorder content (fraction disordered): 0.07692307692307693
Curated region start positions: 241
Curated region end positions: 260
Curated region terms: disorder
Domain/feature annotations: 14-3-3 protein
Cross-references: PDB:1O9C, PDB:1O9D, PDB:1O9E, PDB:1O9F
Sequence:
MAVAPTAREENVYMAKLAEQAERYEEMVEFMEKVSNSLGSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEESRGNEEHVNSIREYRSKIENELSKICDGILKLLDAKLIPSAASGDSKVFYLKMKGDYHRYLAEFKTGAERKEAAESTLTAYKAAQDIATTELAPTHPIRLGLALNFSVFYYEILNSPDRACNLAKQAFDEAIAELDTLGEESYKDSTLIMQLLRDNLTLWTSDMQDDGADEIKEDPKPDEAKN
Protein: Meckelin
UniProt accession: Q5HYA8
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: MKS3, TMEM67
Length: 995 residues
Disorder content (fraction disordered): 0.11256281407035176
Dataset labels: NDDs-related proteins
Curated region start positions: 1, 644, 793, 849
Curated region end positions: 36, 665, 827, 867
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: Meckelin (Transmembrane protein 67)
Cross-references: EMDB:31584, PDB:7FH1
Sequence:
MATRGGAGVAMAVWSLLSARAVTAFLLLFLPRFLQAQTFSFPFQQPEKCDNNQYFDISALSCVPCGANQRQDARGTSCVCLPGFQMISNNGGPAIICKKCPENMKGVTEDGWNCISCPSDLTAEGKCHCPIGHILVERDINGTLLSQATCELCDGNENSFMVVNALGDRCVRCEPTFVNTSRSCACSEPNILTGGLCFSSTGNFPLRRISAARYGEVGMSLTSEWFAKYLQSSAAACWVYANLTSCQALGNMCVMNMNSYDFATFDACGLFQFIFENTAGLSTVHSISFWRQNLPWLFYGDQLGLAPQVLSSTSLPTNFSFKGENQNTKLKFVAASYDIRGNFLKWQTLEGGVLQLCPDTETRLNAAYSFGTTYQQNCEIPISKILIDFPTPIFYDVYLEYTDENQHQYILAVPVLNLNLQHNKIFVNQDSNSGKWLLTRRIFLVDAVSGRENDLGTQPRVIRVATQISLSVHLVPNTINGNIYPPLITIAYSDIDIKDANSQSVKVSFSVTYEMDHGEAHVQTDIALGVLGGLAVLASLLKTAGWKRRIGSPMIDLQTVVKFLVYYAGDLANVFFIITVGTGLYWLIFFKAQKSVSVLLPMPIQEERFVTYVGCAFALKALQFLHKLISQITIDVFFIDWERPKGKVLKAVEGEGGVRSATVPVSIWRTYFVANEWNEIQTVRKINSLFQVLTVLFFLEVVGFKNLALMDSSSSLSRNPPSYIAPYSCILRYAVSAALWLAIGIIQVVFFAVFYERFIEDKIRQFVDLCSMSNISVFLLSHKCFGYYIHGRSVHGHADTNMEEMNMNLKREAENLCSQRGLVPNTDGQTFEIAISNQMRQHYDRIHETLIRKNGPARLLSSSASTFEQSIKAYHMMNKFLGSFIDHVHKEMDYFIKDKLLLERILGMEFMEPMEKSIFYNDEGYSFSSVLYYGNEATLLIFDLLFFCVVDLACQNFILASFLTYLQQEIFRYIRNTVGQKNLASKTLVDQRFLI
Protein: Triggering receptor expressed on myeloid cells 2
UniProt accession: Q9NZC2
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: TREM2
Length: 230 residues
Disorder content (fraction disordered): 0.26956521739130435
Dataset labels: Age-related disorders proteins
Curated region start positions: 131, 189, 189, 190
Curated region end positions: 174, 206, 198, 194
Curated region terms: disorder, disorder, disorder to order, limited proteolysis display site
Domain/feature annotations: Immunoglobulin V-set domain
Cross-references: BMRB:50263, BMRB:50265, PDB:6B8O, PDB:6Z0G, PDB:6Z0I
Sequence:
MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPCQRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTLRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLACIFLIKILAASALWAAAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT
Protein: Synaptotagmin-1
UniProt accession: P21579
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: SVP65, SYT, SYT1
Length: 422 residues
Disorder content (fraction disordered): 0.14691943127962084
Dataset labels: NDDs-related proteins
Curated region start positions: 81, 81, 81, 81, 81, 101, 81, 81, 81, 81
Curated region end positions: 142, 142, 142, 142, 142, 119, 142, 142, 98, 98
Curated region terms: disorder, flexible linker, flexible linker, disorder, lipid binding, lipid binding, vesicle organization, regulation of calcium ion binding, presynaptic membrane, phospholipid binding
Domain/feature annotations: C2 domain, C2 domain
Sequence:
MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVKK
Protein: Aurein-2.5
UniProt accession: P69019
Organism: Ranoidea aurea
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Amphibia, Batrachia, Anura, Neobatrachia, Hyloidea, Hylidae, Pelodryadinae, Ranoidea
Length: 72 residues
Disorder content (fraction disordered): 0.2222222222222222
Curated region start positions: 50, 50, 50, 50, 50, 50, 50, 50
Curated region end positions: 65, 65, 65, 65, 65, 65, 65, 65
Curated region terms: disorder, disorder to order, order, lipid binding, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, pore formation in membrane of another organism, channel activity
Domain/feature annotations: Frog skin active peptide family signal and propeptide
Cross-references: BMRB:34284, PDB:6GS9
Sequence:
MAFLKKSLFLVLFLGLVSLSICEKEKRQNEEDEDENEAANHEEGSEEKRGLFDIVKKVVGAFGSLGKRNDLE
Protein: (rape) hypothetical protein
UniProt accession: A0A078IB52
Organism: Brassica napus
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Brassiceae, Brassica
Gene names: BnaC09g11090D, DARMORV10_C09P17210.1, GSBRNA2T00084185001
Length: 150 residues
Disorder content (fraction disordered): 1
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 1, 1
Curated region end positions: 150, 5, 150
Curated region terms: disorder, acetylation display site, RNA binding
Sequence:
MQYYETREKEYYDVAQGQSRQSYGQNHQGYGQSQSRPVYGNSPTLNYRSHGGFLDGLFKGKNGQKGQNGLGSFLGQHKNQDTNQGHGHGKLLGQHQKKTHETNKGVNGLGMFINNGEKKHKKQNEHKKKKNKDGHASGNESGSSSGSDSE
Protein: Mechanosensitive ion channel protein 10
UniProt accession: Q9LYG9
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: At5g12080, F14F18.230, MSL10, MXC9.3
Length: 734 residues
Disorder content (fraction disordered): 0.4891008174386921
Curated region start positions: 1, 1, 335, 397, 469, 313, 1
Curated region end positions: 164, 165, 386, 431, 480, 506, 164
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, self-assembly
Domain/feature annotations: Mechanosensitive ion channel, beta-domain, Mechanosensitive ion channel protein Msy1-like, transmembrane domain
Cross-references: EMDB:41164, EMDB:41166, PDB:8TDJ, PDB:8TDL
Sequence:
MAEQKSSNGGGGGGDVVINVPVEEASRRSKEMASPESEKGVPFSKSPSPEISKLVGSPNKPPRAPNQNNVGLTQRKSFARSVYSKPKSRFVDPSCPVDTSILEEEVREQLGAGFSFSRASPNNKSNRSVGSPAPVTPSKVVVEKDEDEEIYKKVKLNREMRSKISTLALIESAFFVVILSALVASLTINVLKHHTFWGLEVWKWCVLVMVIFSGMLVTNWFMRLIVFLIETNFLLRRKVLYFVHGLKKSVQVFIWLCLILVAWILLFNHDVKRSPAATKVLKCITRTLISILTGAFFWLVKTLLLKILAANFNVNNFFDRIQDSVFHQYVLQTLSGLPLMEEAERVGREPSTGHLSFATVVKKGTVKEKKVIDMGKVHKMKREKVSAWTMRVLMEAVRTSGLSTISDTLDETAYGEGKEQADREITSEMEALAAAYHVFRNVAQPFFNYIEEEDLLRFMIKEEVDLVFPLFDGAAETGRITRKAFTEWVVKVYTSRRALAHSLNDTKTAVKQLNKLVTAILMVVTVVIWLLLLEVATTKVLLFFSTQLVALAFIIGSTCKNLFESIVFVFVMHPYDVGDRCVVDGVAMLVEEMNLLTTVFLKLNNEKVYYPNAVLATKPISNYFRSPNMGETVEFSISFSTPVSKIAHLKERIAEYLEQNPQHWAPVHSVVVKEIENMNKLKMALYSDHTITFQENRERNLRRTELSLAIKRMLEDLHIDYTLLPQDINLTKKN
Protein: Vacuolar protein-sorting-associated protein 60
UniProt accession: Q03390
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: CHM5, MOS10, VPS60, YDR486C
Length: 229 residues
Disorder content (fraction disordered): 0.2576419213973799
Curated region start positions: 128, 128, 128, 140, 128, 128
Curated region end positions: 186, 186, 186, 183, 186, 186
Curated region terms: disorder, disorder, disorder to order, protein binding, protein binding, protein binding
Domain/feature annotations: Snf7
Cross-references: PDB:2LUH
Sequence:
MNRIFGYGNKKSHDQLLQESNQSMNQAQQSLSNRISQLDTQIAQLNFQLQNIQKNLQRSNNKQPSLRKQALKILNKRKQLENMKDSLDSQSWSMTQAQLTNDNLQNTMITINALKQTNNAMKAQYGKINIDKLQDMQDEMLDLIEQGDELQEVLAMNNNSGELDDISDAELDAELDALAQEDFTLPTSENSLGNDMPSYLLGANAPPAFIDEEPNLDTEDKNKALESAQ
Protein: Vacuolar protein sorting-associated protein VTA1
UniProt accession: Q06263
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: VTA1, YLR181C
Length: 330 residues
Disorder content (fraction disordered): 0.03333333333333333
Curated region start positions: 65, 65, 65, 65, 65
Curated region end positions: 75, 75, 75, 75, 75
Curated region terms: disorder, disorder to order, protein binding, protein binding, protein binding
Domain/feature annotations: Vta1 like, Vta1 C-terminal domain
Cross-references: PDB:2LUH, PDB:2RKK
Sequence:
MASNAARVVATAKDFDKVGLGIIGYYLQLYAVELILSEEDRSQEMTALATELLDTIEAFKKEIGGESEAEDSDKSLHVMNTLIHDQEKAKIYMLNFTMSLYNEKLKQLKDGPWDVMLKRSLWCCIDLFSCILHLWKENISETSTNSLQKRIKYCKIYLSKLAKGEIGSSDEKTLDYADFADDSEEIKDEDVDHQTSDLENNNNDKVEGLAPKDQTTSYEPVDEVPEFIDDADSVNEEEQTVDKNEDAITKDEQQVVKKEVDLTRPSAPSEPAAAEHKSYTKDELTKIMDRASKIEQIQKLAKYAISALNYEDLPTAKDELTKALDLLNSI
Protein: N-cym protein
UniProt accession: P40205
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CYMN, MYCNOS, NCYM
Length: 109 residues
Disorder content (fraction disordered): 1
Dataset labels: Cancer-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 1, 1, 1, 1
Curated region end positions: 109, 109, 109, 109, 109, 109, 109, 109, 109, 109
Curated region terms: disorder, disorder, protein stabilization, protein binding, protein binding, negative regulation of protein kinase activity, negative regulation of apoptotic process, positive regulation of cell migration, negative regulation of apoptotic process, positive regulation of cell migration
Sequence:
MQHPPCEPGNCLSLKEKKITEGSGGVCWGGETDASNPAPALTACCAAEREANVEQGLAGRLLLCNYERRVVRRCKIAGRGRAPLGTRPLDVSSFKLKEEGRPPCLKINK