LiteFold/DisProt huggingface dataset:
Protein: Structural polyprotein
UniProt accession: Q703G9
Organism: Infectious pancreatic necrosis virus (strain Sp)
Taxonomy: Viruses, Riboviria, Orthornavirae, Birnaviridae, Aquabirnavirus
Length: 972 residues
Disorder content (fraction disordered): 0.01440329218106996
Dataset labels: Viral proteins
Curated region start positions: 429
Curated region end positions: 442
Curated region terms: disorder
Domain/feature annotations: Birnavirus VP2 protein, Birnavirus VP3 protein, Birnavirus VP4 protein
Cross-references: PDB:3IDE
Sequence:
MNTNKATATYLKSIMLPETGPASIPDDITERHILKQETSSYNLEVSESGSGVLVCFPGAPGSRIGAHYRWNANQTGLEFDQWLETSQDLKKAFNYGRLISRKYDIQSSTLPAGLYALNGTLNAATFEGSLSEVESLTYNSLMSLTTNPQDKVNNQLVTKGVTVLNLPTGFDKPYVRLEDETPQGLQSMNGAKMRCTAAIAPRRYEIDLPSQRLPPVPATGTLTTLYEGNADIVNSTTVTGDINFSLAEQPADETKFDFQLDFMGLDNDVPVVTVVSSVLATNDNYRGVSAKMTQSIPTENITKPITRVKLSYKINQQTAIGNVATLGTMGPASVSFSSGNGNVPGVLRPITLVAYEKMTPLSILTVAGVSNYELIPNPELLKNMVTRYGKYDPEGLNYAKMILSHREELDIRTVWRTEEYKERTRVFNEITDFSSDLPTSKAWGWRDIVRGIRKVAAPVLSTLFPMAAPLIGMADQFIGDLTKTNAAGGRYHSMAAGGRYKDVLESWASGGPDGKFSRALKNRLESANYEEVELPPPSKGVIVPVVHTVKSAPGEAFGSLAIIIPGEYPELLDANQQVLSHFANDTGSVWGIGEDIPFEGDNMCYTALPLKEIKRNGNIVVEKIFAGPIMGPSAQLGLSLLVNDIEDGVPRMVFTGEIADDEETIIPICGVDIKAIAAHEQGLPLIGNQPGVDEEVRNTSLAAHLIQTGTLPVQRAKGSNKRIKYLGELMASNASGMDEELQRLLNATMARAKEVQDAEIYKLLKLMAWTRKNDLTDHMYEWSKEDPDALKFGKLISTPPKHPEKPKGPDQHHAQEARATRISLDAVRAGADFATPEWVALNNYRGPSPGQFKYYLITGREPEPGDEYEDYIKQPIVKPTDMNKIRRLANSVYGLPHQEPAPEEFYDAVAAVFAQNGGRGPDQDQMQDLRELARQMKRRPRNADAPRRTRAPAEPAPPGRSRFTPSGDNAEV
Protein: ADP-sugar pyrophosphatase
UniProt accession: Q9UKK9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSPC115, NUDIX5, NUDT5
Length: 219 residues
Disorder content (fraction disordered): 0.0593607305936073
Curated region start positions: 1
Curated region end positions: 13
Curated region terms: disorder
Domain/feature annotations: NUDIX domain
Cross-references: PDB:2DSB, PDB:2DSC, PDB:2DSD
Sequence:
MESQEPTESSQNGKQYIISEELISEGKWVKLEKTTYMDPTGKTRTWESVKRTTRKEQTADGVAVIPVLQRTLHYECIVLVKQFRPPMGGYCIEFPAGLIDDGETPEAAALRELEEETGYKGDIAECSPAVCMDPGLSNCTIHIVTVTINGDDAENARPKPKPGDGEFVEVISLPKNDLLQRLDALVAEEHLTVDARVYSYALALKHANAKPFEVPFLKF
Protein: Protein Tat
UniProt accession: P04610
Organism: Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: tat
Length: 86 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 86, 86, 86, 86, 86, 86
Curated region terms: disorder, viral gene expression, regulatory region RNA binding, disorder, viral gene expression, viral gene expression
Domain/feature annotations: Transactivating regulatory protein (Tat)
Cross-references: PDB:1JFW
Sequence:
MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTTKALGISYGRKKRRQRRRPPQGSQTHQVSLSKQPTSQPRGDPTGPKE
Protein: Protein Tat
UniProt accession: P04613
Organism: Human immunodeficiency virus type 1 group M subtype A (isolate MAL)
Taxonomy: Viruses, Riboviria, Pararnavirae, Artverviricota, Revtraviricetes, Ortervirales, Retroviridae, Orthoretrovirinae, Lentivirus
Gene names: tat
Length: 87 residues
Disorder content (fraction disordered): 1
Dataset labels: Viral proteins, RNA-binding proteins
Curated region start positions: 1, 1, 1, 1
Curated region end positions: 87, 87, 87, 87
Curated region terms: disorder, regulatory region RNA binding, viral gene expression, viral gene expression
Domain/feature annotations: Transactivating regulatory protein (Tat)
Sequence:
MDPVDPNLEPWNHPGSQPRTPCNKCYCKKCCYHCQMCFITKGLGISYGRKKRRQRRRPPQGNQAHQDPLPEQPSSQHRGDHPTGPKE
Protein: Nucleoprotein
UniProt accession: A0A2Z5UJ33
Organism: Influenza A virus
Taxonomy: Viruses, Riboviria, Orthornavirae, Negarnaviricota, Polyploviricotina, Insthoviricetes, Articulavirales, Orthomyxoviridae, Alphainfluenzavirus
Gene names: NP
Length: 498 residues
Disorder content (fraction disordered): 0.08634538152610442
Dataset labels: Viral proteins
Curated region start positions: 8, 73, 203, 8
Curated region end positions: 21, 91, 212, 21
Curated region terms: disorder, disorder, disorder, flexible N-terminal tail
Cross-references: PDB:2IQH
Sequence:
MATKGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNKYLEEHPSAGKDPKKTGGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPGNAEFEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLVGIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTNQQRASSGQISIQPTFSVQRNLPFDRPTIMAAFTGNTEGRTSDMRTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFFGDNAEEYDN
Protein: Phospho-2-dehydro-3-deoxyheptonate aldolase
UniProt accession: Q9K169
Organism: Neisseria meningitidis serogroup B (strain MC58)
Taxonomy: Bacteria, Proteobacteria, Betaproteobacteria, Neisseriales, Neisseriaceae, Neisseria
Gene names: NMB0307, aroG
Length: 351 residues
Disorder content (fraction disordered): 0.039886039886039885
Curated region start positions: 1, 1
Curated region end positions: 14, 14
Curated region terms: disorder, flexible N-terminal tail
Domain/feature annotations: DAHP synthetase I family
Cross-references: PDB:4UMA, PDB:4UMB, PDB:4UMC
Sequence:
MTHHYPTDDIKIKEVKELLPPIAHLYELPISKEASGLVHRTRQEISDLVHGRDKRLLVIIGPCSIHDPKAALEYAERLLKLRKQYENELLIVMRVYFEKPRTTVGWKGLINDPHLDGTFDINFGLRQARSLLLSLNNMGMPASTEFLDMITPQYYADLISWGAIGARTTESQVHRELASGLSCPVGFKNGTDGNLKIAIDAIGAASHSHHFLSVTKAGHSAIVHTGGNPDCHVILRGGKEPNYDAEHVSEAAEQLRAAGVTDKLMIDCSHANSRKDYTRQMEVAQDIAAQLEQDGGNIMGVMVESHLVEGRQDKPEVYGKSITDACIGWGATEELLALLAGANKKRMARAS
Protein: Glutathione S-transferase 1
UniProt accession: P46434
Organism: Onchocerca volvulus
Taxonomy: Eukaryota, Metazoa, Ecdysozoa, Nematoda, Chromadorea, Rhabditida, Spirurina, Spiruromorpha, Filarioidea, Onchocercidae, Onchocerca
Gene names: GST1, GSTA
Length: 235 residues
Disorder content (fraction disordered): 0.09787234042553192
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 11
Curated region end positions: 33
Curated region terms: disorder
Domain/feature annotations: Glutathione S-transferase, N-terminal domain, Glutathione S-transferase, C-terminal domain
Cross-references: PDB:2HNL
Sequence:
FITMNFVVEAASSNANQAITSENSIKPKGKLQPQMEKYTLTYFNGRGRAEVIRLLFALANVSYEDNRITRDEWKYLKPRTPFGHVPMLNVSGNVLGESHAIELLLGGRFGLLGTNDWEEAKIMAVVLNIDELFQKLIPWTHEKNTTKKAELFRNLSESDVMPFLGRYEKFLKESTTGHIVGNKVSVADLTVFNMLMTLDDEVKLEEYPQLASFVNKIGQMPGIKEWIKKRPKTYF
Protein: Lipoprotein
UniProt accession: Q7BMQ8
Organism: Neisseria meningitidis
Taxonomy: Bacteria, Proteobacteria, Betaproteobacteria, Neisseriales, Neisseriaceae, Neisseria
Gene names: B1A92_06690, gna1946
Length: 287 residues
Disorder content (fraction disordered): 0.14634146341463414
Curated region start positions: 1
Curated region end positions: 42
Curated region terms: disorder
Domain/feature annotations: NlpA lipoprotein
Cross-references: BMRB:17250
Sequence:
MKTFFKTLSAAALALILAACGGQKDSAPAASASAAADNGAAKKEIVFGTTVGDFGDMVKEQIQPELEKKGYTVKLVEFTDYVRPNLALAEGELDINVFQHKPYLDDFKKEHNLDITEVFQVPTAPLGLYPGKLKSLEEVKDGSTVSAPNDPSNFARVLVMLDELGWIKLKDGINPLTASKADIAENLKNIKIVELEAAQLPRSRADVDFAVVNGNYAISSGMKLTEALFQEPSFAYVNWSAVKTADKDSQWLKDVTEAYNSDAFKAYAHKRFEGYKSPAAWNEGAAK
Protein: Protein AIG2 C
UniProt accession: Q9MBH1
Organism: Arabidopsis thaliana
Taxonomy: Eukaryota, Viridiplantae, Streptophyta, Embryophyta, Tracheophyta, Spermatophyta, Magnoliopsida, eudicotyledons, Gunneridae, Pentapetalae, rosids, malvids, Brassicales, Brassicaceae, Camelineae, Arabidopsis
Gene names: AIG2C, At3g28950, K5K13.6
Length: 165 residues
Disorder content (fraction disordered): 0.18181818181818185
Curated region start positions: 148, 110
Curated region end positions: 165, 121
Curated region terms: disorder, disorder
Domain/feature annotations: Gamma-glutamyl cyclotransferase, AIG2-like
Cross-references: BMRB:15295, PDB:2JQV
Sequence:
MTSSDPQSHNVFVYGSILEPAVAAVILDRTADTVPAVLHGYHRYKLKGLPYPCIVSSDSGKVNGKVITGVSDAELNNFDVIEGNDYERVTVEVVRMDNSEKVKVETYVWVNKDDPRMYGEWDFEEWRVVHAEKFVETFRKMLEWNKNPNGKSMEEAVGSLLSSGD
Protein: Peptidyl-prolyl cis-trans isomerase FKBP8
UniProt accession: Q14318
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: FKBP38, FKBP8
Length: 412 residues
Disorder content (fraction disordered): 0.17718446601941748
Dataset labels: Autophagy-related proteins
Curated region start positions: 1, 1, 1, 1, 1, 1, 151, 1, 357, 23, 23, 23, 23, 23, 23, 23
Curated region end positions: 32, 32, 32, 32, 32, 34, 165, 34, 380, 28, 28, 28, 28, 28, 28, 28
Curated region terms: disorder, calmodulin binding, protein binding, calmodulin binding, self-inhibition, disorder, disorder, calmodulin binding, disorder, protein binding, protein binding, protein binding, regulation of mitophagy, regulation of mitophagy, protein binding, protein localization to mitochondrion
Domain/feature annotations: FKBP-type peptidyl-prolyl cis-trans isomerase, Tetratricopeptide repeat
Cross-references: PDB:5MGX
Sequence:
MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQPPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN
Protein: Imidazole glycerol phosphate synthase hisHF
UniProt accession: P33734
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: HIS7, YBR1640, YBR248C
Length: 552 residues
Disorder content (fraction disordered): 0.02717391304347826
Curated region start positions: 261
Curated region end positions: 275
Curated region terms: disorder
Domain/feature annotations: Glutamine amidotransferase class-I, Histidine biosynthesis protein
Cross-references: PDB:1JVN
Sequence:
MPVVHVIDVESGNLQSLTNAIEHLGYEVQLVKSPKDFNISGTSRLILPGVGNYGHFVDNLFNRGFEKPIREYIESGKPIMGICVGLQALFAGSVESPKSTGLNYIDFKLSRFDDSEKPVPEIGWNSCIPSENLFFGLDPYKRYYFVHSFAAILNSEKKKNLENDGWKIAKAKYGSEEFIAAVNKNNIFATQFHPEKSGKAGLNVIENFLKQQSPPIPNYSAEEKELLMNDYSNYGLTRRIIACLDVRTNDQGDLVVTKGDQYDVREKSDGKGVRNLGKPVQLAQKYYQQGADEVTFLNITSFRDCPLKDTPMLEVLKQAAKTVFVPLTVGGGIKDIVDVDGTKIPALEVASLYFRSGADKVSIGTDAVYAAEKYYELGNRGDGTSPIETISKAYGAQAVVISVDPKRVYVNSQADTKNKVFETEYPGPNGEKYCWYQCTIKGGRESRDLGVWELTRACEALGAGEILLNCIDKDGSNSGYDLELIEHVKDAVKIPVIASSGAGVPEHFEEAFLKTRADACLGAGMFHRGEFTVNDVKEYLLEHGLKVRMDEE
Protein: Syntaxin-17
UniProt accession: P56962
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: STX17
Length: 302 residues
Disorder content (fraction disordered): 0.38079470198675497
Dataset labels: Autophagy-related proteins
Curated region start positions: 142, 142, 142, 94, 94, 94, 171, 167, 142, 168, 168, 142, 142, 142, 142
Curated region end positions: 228, 228, 228, 121, 121, 121, 176, 188, 167, 228, 228, 228, 228, 228, 228
Curated region terms: disorder, disorder, protein binding, disorder, order to disorder, protein binding, protein binding, protein binding, disorder, protein binding, protein binding, protein binding, order, disorder to order, self-regulatory activity
Domain/feature annotations: STX17-like, N-terminal domain
Cross-references: PDB:7BV4, PDB:7BV6
Sequence:
MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGRTVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQFNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLIELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIGGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKKCS
Protein: Inositol polyphosphate multikinase
UniProt accession: P07250
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: ARG82, ARGR3, GSL3, IPK2, YD9395.06C, YDR173C
Length: 355 residues
Disorder content (fraction disordered): 0.28450704225352114
Curated region start positions: 287, 76, 46, 1, 287
Curated region end positions: 316, 110, 57, 24, 303
Curated region terms: disorder, disorder, disorder, disorder, protein stabilization
Domain/feature annotations: Inositol polyphosphate kinase
Cross-references: PDB:2IEW, PDB:2IF8
Sequence:
MDTVNNYRVLEHKAAGHDGTLTDGDGLLIFKPAFPQELEFYKAIQVRDVSRRKSSADGDAPLCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLSDSTDNLDSIPVKSEKSKQYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTDQNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLNDVDKLMRDDFIDDDDDDDDNDDDDDDDAEGSSEGPKDKKTTGSLSSMSLIDFAHSEITPGKGYDENVIEGVETLLDIFMKF
Protein: Growth hormone secretagogue receptor type 1
UniProt accession: Q92847
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: GHSR
Length: 366 residues
Disorder content (fraction disordered): 0.07650273224043716
Curated region start positions: 339, 339, 339
Curated region end positions: 366, 366, 366
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: 7 transmembrane receptor (rhodopsin family)
Sequence:
MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWTESSINT
Protein: Nuclear receptor coactivator 1
UniProt accession: P70365
Organism: Mus musculus
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Glires, Rodentia, Myomorpha, Muroidea, Muridae, Murinae, Mus, Mus
Gene names: Ncoa1, Src1
Length: 1447 residues
Disorder content (fraction disordered): 0.013130615065653077
Dataset labels: Autophagy-related proteins
Curated region start positions: 368, 371, 367, 368
Curated region end positions: 385, 385, 385, 385
Curated region terms: disorder, disorder, disorder, disorder
Domain/feature annotations: PAS fold, Nuclear receptor coactivator, DUF1518, Nuclear receptor coactivator, DUF1518, Nuclear receptor coactivator, Steroid receptor coactivator, PAS domain, Unstructured region on nuclear receptor coactivator protein, Nuclear receptor coactivators bHLH domain
Cross-references: PDB:1OJ5, PDB:5NWX
Sequence:
MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPEDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNRQQSSDLNSSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGTGIALSQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKEIASILNEMIQSDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYLLDKDEKDLRSTPNLCLDDVKVKVEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLDQFDQLLPTLEKAAQLPSLCETDRMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANNTLTTINQNKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGLSGPFQGMVRQKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAMLMRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLATRSSMVNRGMAGNMGGQFGAGISPQMQQNVFQYPGPGLVPQGEATFAPSLSPGSSMVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNNMSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGNQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE
Protein: Induced myeloid leukemia cell differentiation protein Mcl-1
UniProt accession: Q07820
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: BCL2L3, MCL1
Length: 350 residues
Disorder content (fraction disordered): 0.03428571428571429
Dataset labels: Autophagy-related proteins
Curated region start positions: 192, 192, 193
Curated region end positions: 201, 201, 203
Curated region terms: disorder, disorder, disorder
Domain/feature annotations: Apoptosis regulator proteins, Bcl-2 family
Cross-references: PDB:2KBW, PDB:5FC4, PDB:5W89
Sequence:
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
Protein: Uncharacterized protein CXorf51A
UniProt accession: A0A1B0GTR3
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: CXorf51, CXorf51A
Length: 108 residues
Disorder content (fraction disordered): 1
Curated region start positions: 1
Curated region end positions: 108
Curated region terms: disorder
Cross-references: BMRB:50944
Sequence:
MAKVTSEPQKPNEDVDEQTPSTSSTKGRKKGKTPRQRRSRSGVKGLKTTRKAKRPLRGSSSQKAGETNTPAGKPKKARGPILRGRYHRLKEKMKKEEADKEQSETSVL
Protein: Phosphatidylinositol 3-kinase catalytic subunit type 3
UniProt accession: Q8NEB9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: PIK3C3, VPS34
Length: 887 residues
Disorder content (fraction disordered): 0.09470124013528748
Dataset labels: Autophagy-related proteins
Curated region start positions: 422, 873, 246, 418, 872, 418, 452, 250, 250, 250
Curated region end positions: 469, 887, 260, 470, 887, 434, 469, 253, 253, 253
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, disorder, selective autophagy, protein binding, selective autophagy
Domain/feature annotations: Phosphatidylinositol 3- and 4-kinase, Phosphoinositide 3-kinase family, accessory domain (PIK domain), Phosphoinositide 3-kinase C2
Cross-references: PDB:4OYS, PDB:4PH4, PDB:7BL1
Sequence:
MGEAEKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVFAEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGGTTVSLFGKYGMFRQGMHDLKVWPNVEADGSEPTKTPGRTSSTLSEDQMSRLAKLTKAHRQGHMVKVDWLDRLTFREIEMINESEKRSSNFMYLMVEFRCVKCDDKEYGIVYYEKDGDESSPILTSFELVKVPDPQMSMENLVESKHHKLARSLRSGPSDHDLKPNAATRDQLNIIVSYPPTKQLTYEEQDLVWKFRYYLTNQEKALTKFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHYTNPTVRRYAVARLRQADDEDLLMYLLQLVQALKYENFDDIKNGLEPTKKDSQSSVSENVSNSGINSAEIDSSQIITSPLPSVSSPPPASKTKEVPDGENLEQDLCTFLISRACKNSTLANYLYWYVIVECEDQDTQQRDPKTHEMYLNVMRRFSQALLKGDKSVRVMRSLLAAQQTFVDRLVHLMKAVQRESGNRKKKNERLQALLGDNEKMNLSDVELIPLPLEPQVKIRGIIPETATLFKSALMPAQLFFKTEDGGKYPVIFKHGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKHGFMQFIQSVPVAEVLDTEGSIQNFFRKYAPSENGPNGISAEVMDTYVKSCAGYCVITYILGVGDRHLDNLLLTKTGKLFHIDFGYILGRDPKPLPPPMKLNKEMVEGMGGTQSEQYQEFRKQCYTAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQSLIDESVHALFAAVVEQIHKFAQYWRK
Protein: Transient receptor potential cation channel subfamily V member 2
UniProt accession: Q9Y5S1
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: TRPV2, VRL
Length: 764 residues
Disorder content (fraction disordered): 0.09424083769633508
Curated region start positions: 2
Curated region end positions: 73
Curated region terms: disorder
Domain/feature annotations: Ion transport protein, Ankyrin repeats (3 copies)
Cross-references: BMRB:51354
Sequence:
MTSPSSSPVFRLETLDGGQEDGSEADRGKLDFGSGLPPMESQFQGEDRKFAPQIRVNLNYRKGTGASQPDPNRFDRDRLFNAVSRGVPEDLAGLPEYLSKTSKYLTDSEYTEGSTGKTCLMKAVLNLKDGVNACILPLLQIDRDSGNPQPLVNAQCTDDYYRGHSALHIAIEKRSLQCVKLLVENGANVHARACGRFFQKGQGTCFYFGELPLSLAACTKQWDVVSYLLENPHQPASLQATDSQGNTVLHALVMISDNSAENIALVTSMYDGLLQAGARLCPTVQLEDIRNLQDLTPLKLAAKEGKIEIFRHILQREFSGLSHLSRKFTEWCYGPVRVSLYDLASVDSCEENSVLEIIAFHCKSPHRHRMVVLEPLNKLLQAKWDLLIPKFFLNFLCNLIYMFIFTAVAYHQPTLKKQAAPHLKAEVGNSMLLTGHILILLGGIYLLVGQLWYFWRRHVFIWISFIDSYFEILFLFQALLTVVSQVLCFLAIEWYLPLLVSALVLGWLNLLYYTRGFQHTGIYSVMIQKVILRDLLRFLLIYLVFLFGFAVALVSLSQEAWRPEAPTGPNATESVQPMEGQEDEGNGAQYRGILEASLELFKFTIGMGELAFQEQLHFRGMVLLLLLAYVLLTYILLLNMLIALMSETVNSVATDSWSIWKLQKAISVLEMENGYWWCRKKQRAGVMLTVGTKPDGSPDERWCFRVEEVNWASWEQTLPTLCEDPSGAGVPRTLENPVLASPPKEDEDGASEENYVPVQLLQSN
Protein: A-kinase anchor protein 5
UniProt accession: P24588
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: AKAP5, AKAP79
Length: 427 residues
Disorder content (fraction disordered): 0.2997658079625293
Curated region start positions: 300, 300, 404, 390, 361, 371, 337, 300, 337, 390
Curated region end positions: 427, 427, 413, 395, 365, 375, 343, 425, 343, 417
Curated region terms: disorder, disorder, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, protein binding, calmodulin binding
Domain/feature annotations: WSK motif
Sequence:
METTISEIHVENKDEKRSAEGSPGAERQKEKASMLCFKRRKKAAKALKPKAGSEAADVARKCPQEAGASDQPEPTRGAWASLKRLVTRRKRSESSKQQKPLEGEMQPAINAEDADLSKKKAKSRLKIPCIKFPRGPKRSNHSKIIEDSDCSIKVQEEAEILDIQTQTPLNDQATKAKSTQDLSEGISRKDGDEVCESNVSNSTTSGEKVISVELGLDNGHSAIQTGTLILEEIETIKEKQDVQPQQASPLETSETDHQQPVLSDVPPLPAIPDQQIVEEASNSTLESAPNGKDYESTEIVAEETKPKDTELSQESDFKENGITEEKSKSEESKRMEPIAIIITDTEISEFDVTKSKNVPKQFLISAENEQVGVFANDNGFEDRTSEQYETLLIETASSLVKNAIQLSIEQLVNEMASDDNKINNLLQ
Protein: Proteasome subunit beta
UniProt accession: A4HSQ5
Organism: Leishmania infantum
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: LINJ_06_0140
Length: 247 residues
Disorder content (fraction disordered): 0.13360323886639677
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 1
Curated region end positions: 33
Curated region terms: disorder
Domain/feature annotations: Proteasome subunit
Cross-references: PDB:6QM7, PDB:6QM8
Sequence:
MIEDHAEYGHNHYPQKLASSTLTLPKQGAKQQQWSPYQDNGGTTAAIAGKDFVILAGDTRLNGDYCLHSRHDQSKIFQLTPYTYMASNGMQADRLQLQQMLKYRVKWYQYNNGGRVPPTKAIAQLMSTLLYHRRFFPYYTFNMVVGLDEEGHGVCYSYDAVGSTEPFLYGTRGSAASFLEPVLDCLINRQHMTAQAPPEMTKEETLAMLKNAFTGAAERDIYTGDSVSFFIITKDGVQRESFELRKD
Protein: Proteasome subunit alpha type
UniProt accession: A0A504Y5E1
Organism: Leishmania donovani
Taxonomy: Eukaryota, Discoba, Euglenozoa, Kinetoplastea, Metakinetoplastina, Trypanosomatida, Trypanosomatidae, Leishmaniinae, Leishmania
Gene names: CGC20_38795, LDHU3_14.0400
Length: 285 residues
Disorder content (fraction disordered): 0.042105263157894736
Dataset labels: Neglected tropical diseases proteins
Curated region start positions: 274
Curated region end positions: 285
Curated region terms: disorder
Domain/feature annotations: Proteasome subunit, Proteasome subunit A N-terminal signature
Cross-references: EMDB:10462, PDB:6TCZ, PDB:6TD5
Sequence:
MSHRYDSRTTTFSPEGRLYQVEYAVEAIQQAGTVIGVCTKDGVVLAGEKMVPHPLFDSENMQDKNTSGEKMYKIAEHIGCSVAGVTSDAYALLNYARLSALRHQYTFQEPMAIEDLCRILCDEKQLYTQYGGVRPYGVSFLLVGWDRYYGYQLYSTEPSGDYSAWSAYAIGQNDQVAHSLLKKDWHENMTLEDGMLLALRVLGKTMDTAKIDLGRVEVAVMRKVPASNVDQLLDPFKHHPKTTPQFQILALSELKPHAERADQAREAEEQAEAERQRQQEQALES