LiteFold/DisProt huggingface dataset:
Protein: Isoform 5 of Tuberin
UniProt accession: P49815-5
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: TSC2, TSC4
Length: 1740 residues
Disorder content (fraction disordered): 0.3022988505747126
Curated region start positions: 50, 644, 937, 1039, 1202, 1689, 1689
Curated region end positions: 126, 682, 970, 1137, 1426, 1740, 1740
Curated region terms: disorder, disorder, disorder, disorder, disorder, disorder, flexible C-terminal tail
Cross-references: EMDB:30708, PDB:7DL2
Sequence:
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTDSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
Protein: Tuftelin-interacting protein 11
UniProt accession: Q9UBB9
Organism: Homo sapiens
Taxonomy: Eukaryota, Metazoa, Chordata, Craniata, Vertebrata, Euteleostomi, Mammalia, Eutheria, Euarchontoglires, Primates, Haplorrhini, Catarrhini, Hominidae, Homo
Gene names: HSPC006, STIP, TFIP11
Length: 837 residues
Disorder content (fraction disordered): 0.4181600955794504
Dataset labels: RNA-binding proteins
Curated region start positions: 1, 1, 1, 1, 1, 1
Curated region end positions: 350, 350, 350, 350, 350, 350
Curated region terms: disorder, disorder, order to disorder, disorder, order to disorder, amyloid-beta formation
Domain/feature annotations: G-patch domain, GC-rich sequence DNA-binding factor-like protein, Tuftelin interacting protein N terminal
Sequence:
MSLSHLYRDGEGRIDDDDDERENFEITDWDLQNEFNPNRQRHWQTKEEATYGVWAERDSDDERPSFGGKRARDYSAPVNFISAGLKKGAAEEAELEDSDDEEKPVKQDDFPKDFGPRKLKTGGNFKPSQKGFAGGTKSFMDFGSWERHTKGIGQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGSERTTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQVKVIDMTGREQKVYYSYSQISHKHNVPDDGLPLQSQQLPQSGKEAKAPGFALPELEHNLQLLIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHEERVISNLSKVLEMVEECERRMQPDCSNPLTLDECARIFETLQDKYYEEYRMSDRVDLAVAIVYPLMKEYFKEWDPLKDCTYGTEIISKWKSLLENDQLLSHGGQDLSADAFHRLIWEVWMPFVRNIVTQWQPRNCDPMVDFLDSWVHIIPVWILDNILDQLIFPKLQKEVENWNPLTDTVPIHSWIHPWLPLMQARLEPLYSPIRSKLSSALQKWHPSDSSAKLILQPWKDVFTPGSWEAFMVKNIVPKLGMCLGELVINPHQQHMDAFYWVIDWEGMISVSSLVGLLEKHFFPKWLQVLCSWLSNSPNYEEITKWYLGWKSMFSDQVLAHPSVKDKFNEALDIMNRAVSSNVGAYMQPGARENIAYLTHTERRKDFQYEAMQERREAENMAQRGIGVAASSVPMNFKDLIETKAEEHNIVFMPVIGKRHEGKQLYTFGRIVIYIDRGVVFVQGEKTWVPTSLQSLIDMAK
Protein: Origin recognition complex subunit 2
UniProt accession: P32833
Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Taxonomy: Eukaryota, Fungi, Dikarya, Ascomycota, Saccharomycotina, Saccharomycetes, Saccharomycetales, Saccharomycetaceae, Saccharomyces
Gene names: ORC2, RRR1, SIR5, YBR0523, YBR060C
Length: 620 residues
Disorder content (fraction disordered): 0.5903225806451613
Curated region start positions: 1, 344, 498, 176
Curated region end positions: 232, 354, 620, 200
Curated region terms: disorder, disorder, disorder, chromatin binding
Domain/feature annotations: Origin recognition complex subunit 2 RecA-like domain, ORC2 WHD
Cross-references: EMDB:25924, PDB:7TJF
Sequence:
MLNGEDFVEHNDILSSPAKSRNVTPKRVDPHGERQLRRIHSSKKNLLERISLVGNERKNTSPDPALKPKTPSKAPRKRGRPRKIQEELTDRIKKDEKDTISSKKKRKLDKDTSGNVNEESKTSNNKQVMEKTGIKEKREREKIQVATTTYEDNVTPQTDDNFVSNSPEPPEPATPSKKSLTTNHDFTSPLKQIIMNNLKEYKDSTSPGKLTLSRNFTPTPVPKNKKLYQTSETKSASSFLDTFEGYFDQRKIVRTNAKSRHTMSMAPDVTREEFSLVSNFFNENFQKRPRQKLFEIQKKMFPQYWFELTQGFSLLFYGVGSKRNFLEEFAIDYLSPKIAYSQLAYENELQQNKPVNSIPCLILNGYNPSCNYRDVFKEITDLLVPAELTRSETKYWGNHVILQIQKMIDFYKNQPLDIKLILVVHNLDGPSIRKNTFQTMLSFLSVIRQIAIVASTDHIYAPLLWDNMKAQNYNFVFHDISNFEPSTVESTFQDVMKMGKSDTSSGAEGAKYVLQSLTVNSKKMYKLLIETQMQNMGNLSANTGPKRGTQRTGVELKLFNHLCAADFIASNEIALRSMLREFIEHKMANITKNNSGMEIIWVPYTYAELEKLLKTVLNTL
Protein: Capsule biosynthesis protein CapD proenzyme
UniProt accession: Q51693
Organism: Bacillus anthracis
Taxonomy: Bacteria, Bacillati, Bacillota, Bacilli, Bacillales, Bacillaceae, Bacillus, Bacillus cereus group
Gene names: BXB0063, GBAA_pXO2_0063, capD, dep, pXO2-55
Length: 528 residues
Disorder content (fraction disordered): 0.0625
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 336, 29
Curated region end positions: 351, 45
Curated region terms: disorder, disorder
Domain/feature annotations: Gamma-glutamyltranspeptidase
Cross-references: PDB:3G9K, PDB:3GA9
Sequence:
MNSFKWGKKIILFCLIVSLMGGIGVSCSFNKIKDSVKQKIDSMGDKGTYGVSASHPLAVEEGMKVLKNGGSAVDAAIVVSYVLGVVELHASGIGGGGGMLIISKDKETFIDYRETTPYFTGNQKPHIGVPGFVAGMEYIHDNYGSLPMGELLQPAINYAEKGFKVDDSLTMRLDLAKPRIYSDKLSIFYPNGEPIETGETLIQTDLARTLKKIQKEGAKGFYEGGVARAISKTAKISLEDIKGYKVEVRKPVKGNYMGYDVYTAPPPFSGVTLLQMLKLAEKKEVYKDVDHTATYMSKMEEISRIAYQDRKKNLGDPNYVNMDPNKMVSDKYISTMKNENGDALSEAEHESTTHFVIIDRDGTVVSSTNTLSNFFGTGKYTAGFFLNNQLQNFGSEGFNSYEPGKRSRTFMAPTVLKKDGETIGIGSPGGNRIPQILTPILDKYTHGKGSLQDIINEYRFTFEKNTAYTEIQLSSEVKNELSRKGLNVKKKVSPAFFGGVQALIKDERDNVITGAGDGRRNGTWKSNK
Protein: Outer membrane autotransporter IcsA
UniProt accession: Q7BCK4
Organism: Shigella flexneri
Taxonomy: Bacteria, Pseudomonadati, Pseudomonadota, Gammaproteobacteria, Enterobacterales, Enterobacteriaceae, Shigella
Gene names: CP0182, icsA, virG
Length: 1102 residues
Disorder content (fraction disordered): 0.016333938294010888
Dataset labels: Bacterial virulence-related proteins
Curated region start positions: 741, 741, 741
Curated region end positions: 758, 758, 758
Curated region terms: disorder, disorder, flexible linker
Domain/feature annotations: Autotransporter beta-domain, Passenger-associated-transport-repeat, Autochaperone Domain Type 1, VirG insertion domain (VID)
Cross-references: PDB:3ML3, PDB:5KE1
Sequence:
MNQIHKFFCNMTQCSQGGAGELPTVKEKTCKLSFSPFVVGASLLLGGPIAFATPLSGTQELHFSEDNYEKLLTPVDGLSPLGAGEDGMDAWYITSSNPSHASRTKLRINSDIMISAGHGGAGDNNDGNSCGGNGGDSITGSDLSIINQGMILGGSGGSGADHNGDGGEAVTGDNLFIINGEIISGGHGGDSYSDSDGGNGGDAVTGVNLPIINKGTISGGNGGNNYGEGDGGNGGDAITGSSLSVINKGTFAGGNGGAAYGYGYDGYGGNAITGDNLSVINNGAILGGNGGHWGDAINGSNMTIANSGYIISGKEDDGTQNVAGNAIHITGGNNSLILHEGSVITGDVQVNNSSILKIINNDYTGTTPTIEGDLCAGDCTTVSLSGNKFTVSGDVSFGENSSLNLAGISSLEASGNMSFGNNVKVEAIINNWAQKDYKLLSADKGITGFSVSNISIINPLLTTGAIDYTKSYISDQNKLIYGLSWNDTDGDSHGEFNLKENAELTVSTILADNLSHHNINSWDGKSLTKSGEGTLILAEKNTYSGFTNINAGILKMGTVEAMTRTAGVIVNKGATLNFSGMNQTVNTLLNSGTVLINNINAPFLPDPVIVTGNMTLEKNGHVILNNSSSNVGQTYVQKGNWHGKGGILSLGAVLGNDNSKTDRLEIAGHASGITYVAVTNEGGSGDKTLEGVQIISTDSSDKNAFIQKGRIVAGSYDYRLKQGTVSGLNTNKWYLTSQMDNQESKQMSNQESTQMSSRRASSQLVSSLNLGEGSIHTWRPEAGSYIANLIAMNTMFSPSLYDRHGSTIVDPTTGQLSETTMWIRTVGGHNEHNLADRQLKTTANRMVYQIGGDILKTNFTDHDGLHVGIMGAYGYQDSKTHNKYTSYSSRGTVSGYTAGLYSSWFQDEKERTGLYMDAWLQYSWFNNTVKGDGLTGEKYSSKGITGALEAGYIYPTIRWTAHNNIDNALYLNPQVQITRHGVKANDYIEHNGTMVTSSGGNNIQAKLGLRTSLISQSCIDKETLRKFEPFLEVNWKWSSKQYGVIMNGMSNHQIGNRNVIELKTGVGGRLADNLSIWGNVSQQLGNNSYRDTQGILGVKYTF
Protein: Functional amyloid subunit FapC
UniProt accession: P0DXF5
Organism: Pseudomonas fluorescens
Taxonomy: Bacteria, Pseudomonadati, Pseudomonadota, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: HZ99_04090, PSUK4_00030, fapC
Length: 250 residues
Disorder content (fraction disordered): 1
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 250, 250, 250, 250, 250
Curated region terms: disorder, amyloid fibril formation, amyloid fibril formation, disorder, disorder
Sequence:
MKPTMALKPLVFALAALMAVAAQAGPAEKWKPTPAPTGTVAAAVTDTQVSKDNKFDDTKTLNNAGANGSLSNSKGNLGANIAAGSGNQQDNAAAITSSAGDAATVFAVADIYQESKDNKFTNKGTQNNALLNNSANNSSGNVGVNVAAGQGNQQKNNLAIVTADGKNVAAASNTEQVSLDNHFLNEASSKHSYKPQYVVNNAGLLNSANNASGNIGVNVAAGAGNQQSNTLTLGSGCTVCAAGTGSKLAF
Protein: Functional amyloid subunit FapB
UniProt accession: P0DXF4
Organism: Pseudomonas fluorescens
Taxonomy: Bacteria, Pseudomonadati, Pseudomonadota, Gammaproteobacteria, Pseudomonadales, Pseudomonadaceae, Pseudomonas
Gene names: HZ99_04085, PSUK4_00020, fapB
Length: 182 residues
Disorder content (fraction disordered): 1
Dataset labels: Condensates-related proteins
Curated region start positions: 1, 1, 1, 1, 1
Curated region end positions: 182, 182, 182, 182, 182
Curated region terms: disorder, amyloid fibril formation, amyloid fibril formation, disorder, disorder
Sequence:
MTHSWLLLTVLGCSAAMADSNNQALIDNAGKQYTGVLSVNQAAGNQHQQINSRAISLGGQASDALIQKLDGKVDPSLNASAAIQGSAFSNGNGILGVNQSAGANNQMINAVRISTGPQSVDDNVLSQQNMTLLPDSRSPSTTGSRQVVTSDQAFTGSRGVVQVNQSAGVGNRMANTLGVTIK