Most Extreme Humans (Reality, English)
Genres: Medical
Status: Running
Premiered: 2026-06-10
Network: TLC
Country: US
Airs on: Wednesday
Air time: 21:00
Runtime: 60 minutes
Most Extreme Humans follows people from around the globe living with the world's rarest and most remarkable physical conditions. From a Filipino man whose hands have grown so large he wears wristwatches as rings, to Brazil, where the world's smallest married couple have a combined height under six feet, to a 19-year-old in India living with the ultra-rare condition known as "werewolf syndrome." This series examines what everyday life looks like when the world is not built with your body in mind.