A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function
Year: 2025
Type: article
Language: en
Topic: Receptor Mechanisms and Signaling
Authors and affiliations:
raw_author_name: Rebecca L. Brouillette
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Frédérique Lussier
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Émile Breault
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Nathan Meneboo
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Malihe Hassanzadeh
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Victoria Tremblay
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Magali Chartier
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Élora Midavaine
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Laurence Ulrich
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Jérôme Côté
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Véronique Blais
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Christine E. Mona
raw_affiliation_strings: Ahmanson Translational Theranostics Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA 90095, USA
Jonsson Comprehensive Cancer Center, UCLA Health, Los Angeles, CA 90095, USA
raw_author_name: Jean-Michel Longpré
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Michel Grandbois
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Pierre-Luc Boudreault
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
RECITAL International Partnership Lab, Université de Caen Normandie, 14000, Caen, France & Université de Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Martin Audet
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Élie Besserer-Offroy
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
François Baclesse Comprehensive Cancer Center, UNICANCER, 14000 Caen, France
Interdisciplinary Research Unit for Cancer Prevention and Treatment – Anticipe, INSERM, U1086, Université de Caen Normandie, 14000 Caen, France
RECITAL International Partnership Lab, Université de Caen Normandie, 14000, Caen, France & Université de Sherbrooke, QC, J1H 5N4, Canada
raw_author_name: Philippe Sarret
raw_affiliation_strings: Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada
RECITAL International Partnership Lab, Université de Caen Normandie, 14000, Caen, France & Université de Sherbrooke, QC, J1H 5N4, Canada