Robust Workflow for Multiclass Host-Gut Microbial Cometabolite Quantitation in Human Stool via 3-Nitrophenylhydrazine Derivatization and LC-MS/MS: A Validated Analytical Platform for Translational Studies
Year: 2025
Type: article
Language: en
Topic: Gut microbiota and health
Authors and affiliations:
raw_author_name: Daniel Zhi Wei Ng
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
raw_author_name: Mingyou Koh
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore
raw_author_name: Adrian Low
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Lin Liu
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Nur Halisah Binte Jumat
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Zixuan Zhang
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Xiu Qi Koh
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Mengtong Zhu
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
raw_author_name: Mark Muthiah
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
Division of Gastroenterology & Hepatology, Department of Medicine
National University Centre for Organ Transplantation
National University Health System
National University Hospital
raw_author_name: Yock Young Dan
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
Division of Gastroenterology & Hepatology, Department of Medicine
National University Hospital
raw_author_name: Jonathan Wei Jie Lee
raw_affiliation_strings: Department of Medicine, Yong Loo Lin School of Medicine, MD6 Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore
Division of Gastroenterology & Hepatology, Department of Medicine
Institute for Health Innovation and Technology (iHealthtech), National University of Singapore, E7, 15 Kent Ridge Crescent, Singapore 119276, Singapore
National University Hospital
raw_author_name: Eric Chun Yong Chan
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore