Novel DNJ Derivative Ameliorates Cardiac Hypertrophy by Targeting OPA1 and Restoring Mitochondrial Health
Year: 2025
Type: article
Language: en
Topic: Mitochondrial Function and Pathology
Authors and affiliations:
raw_author_name: Xue Ding
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Yangwei Jiang
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Institute of Quantitative Biology (Y.J., L.F., D.B., D.Z., R.Z.), Zhejiang University, Hangzhou, China
raw_author_name: Xiaochen Wang
raw_affiliation_strings: Institute of Translational Medicine (X.W., P.L.), Zhejiang University, Hangzhou, China
raw_author_name: Chujun Li
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Zhengyi Kong
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Lei Fu
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Institute of Quantitative Biology (Y.J., L.F., D.B., D.Z., R.Z.), Zhejiang University, Hangzhou, China
raw_author_name: Zhaoying Lei
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Huajian Cai
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Yufei Dong
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Chengyu Shi
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Xinwan Su
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
raw_author_name: Tilo Kunath
raw_affiliation_strings: Institute for Stem Cell Research, School of Biological Sciences, The University of Edinburgh, United Kingdom (T.K.)
raw_author_name: Ziyi Wang
raw_affiliation_strings: Innovative Institute of Basic Medical Sciences (Z.W.), Zhejiang University, Hangzhou, China
raw_author_name: Damiano Buratto
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Institute of Quantitative Biology (Y.J., L.F., D.B., D.Z., R.Z.), Zhejiang University, Hangzhou, China
raw_author_name: Aifu Lin
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Zhejiang Key Laboratory of Cell and Molecular Intelligence Design and Development Applications, Hangzhou, China (A.L., J.S., D.Z., R.Z., Q.Y.)
Zhejiang University-Lishui Joint Innovation Center for Life and Health and Lishui Lvgu Institute for Life and Health, China (A.L., R.Z., Q.Y.)
raw_author_name: Jianzhong Shao
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Zhejiang Key Laboratory of Cell and Molecular Intelligence Design and Development Applications, Hangzhou, China (A.L., J.S., D.Z., R.Z., Q.Y.)
raw_author_name: Dong Zhang
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Institute of Quantitative Biology (Y.J., L.F., D.B., D.Z., R.Z.), Zhejiang University, Hangzhou, China
Zhejiang Key Laboratory of Cell and Molecular Intelligence Design and Development Applications, Hangzhou, China (A.L., J.S., D.Z., R.Z., Q.Y.)
raw_author_name: Zhong Liu
raw_affiliation_strings: The First Affiliated Hospital (Z. Liu, R.Z., Q.Y.), Zhejiang University School of Medicine, Hangzhou, China
raw_author_name: Ping Liang
raw_affiliation_strings: Institute of Translational Medicine (X.W., P.L.), Zhejiang University, Hangzhou, China
Key Laboratory of Combined Multi-Organ Transplantation, Ministry of Public Health, the First Affiliated Hospital (P.L.), Zhejiang University School of Medicine, Hangzhou, China
raw_author_name: Ruhong Zhou
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
Institute of Quantitative Biology (Y.J., L.F., D.B., D.Z., R.Z.), Zhejiang University, Hangzhou, China
The First Affiliated Hospital (Z. Liu, R.Z., Q.Y.), Zhejiang University School of Medicine, Hangzhou, China
Zhejiang Key Laboratory of Cell and Molecular Intelligence Design and Development Applications, Hangzhou, China (A.L., J.S., D.Z., R.Z., Q.Y.)
Zhejiang University-Lishui Joint Innovation Center for Life and Health and Lishui Lvgu Institute for Life and Health, China (A.L., R.Z., Q.Y.)
raw_author_name: Qingfeng Yan
raw_affiliation_strings: College of Life Sciences (X.D., Y.J., C.L., Z.K., L.F., Z. Lei, H.C., Y.D., C.S., X.S., D.B., A.L., J.S., D.Z., R.Z., Q.Y.), Zhejiang University, Hangzhou, China
The First Affiliated Hospital (Z. Liu, R.Z., Q.Y.), Zhejiang University School of Medicine, Hangzhou, China
Zhejiang Key Laboratory of Cell and Molecular Intelligence Design and Development Applications, Hangzhou, China (A.L., J.S., D.Z., R.Z., Q.Y.)
Zhejiang University-Lishui Joint Innovation Center for Life and Health and Lishui Lvgu Institute for Life and Health, China (A.L., R.Z., Q.Y.)