Venetoclax resistance in preclinical KMT2A-rearranged acute lymphoblastic leukemia models is characterized by high inter- and intra-model heterogeneity
Year: 2025
Type: article
Language: en
Topic: Acute Lymphoblastic Leukemia research
Authors and affiliations:
raw_author_name: Anna Richter
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany. anna.richter@med.uni-rostock.de
raw_author_name: Lea Kinsky
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
raw_author_name: Sandra Lange
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
raw_author_name: Nares Trakooljul
raw_affiliation_strings: Research Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany
raw_author_name: Frieder Hadlich
raw_affiliation_strings: Research Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany
raw_author_name: Anett Sekora
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
raw_author_name: Gudrun Knuebel
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
Institute of Medical Genetics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany
raw_author_name: Saskia Krohn
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
Institute of Medical Genetics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany
raw_author_name: Christian Schmidt
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
raw_author_name: Michelle Busch
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
raw_author_name: Tim Schreiber
raw_affiliation_strings: Rudolf-Zenker Institute of Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18057, Rostock, Germany
raw_author_name: Simone Kumstel
raw_affiliation_strings: Rudolf-Zenker Institute of Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18057, Rostock, Germany
raw_author_name: Klaus Wimmers
raw_affiliation_strings: Research Institute for Farm Animal Biology, Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany
raw_author_name: Hugo Murua Escobar
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany
Institute of Medical Genetics, Rostock University Medical Center, Ernst-Heydemann-Str. 8, 18057, Rostock, Germany
raw_author_name: Christian Junghanss
raw_affiliation_strings: Department of Internal Medicine, Clinic for Hematology, Hemostasis, Oncology, Stem Cell Therapy and Palliative Medicine, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany