Intravenous Delivery of a Gene Therapy Vector that Expresses an Antitransferrin Receptor 1 Nanobody-I2S Fusion Protein Rescued Central Nervous System Lysosomal Burden in Mucopolysaccharidosis II Mice
Year: 2025
Type: article
Language: en
Topic: Lysosomal Storage Disorders Research
Authors and affiliations:
raw_author_name: Wanida Ruangsiriluk
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Sarah Melissa P. Jacobo
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Andrea Iskenderian
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Meera Modi
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Nancy Chen
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Brian Felice
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Shipeng Yuan
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Shreya T. Mukherji
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Melody Rivera Hernandez
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Shashank Sunkara
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Amanda MacDonald
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Girija Rajarshi
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Kathleen Palmieri
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Robert Crooker
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Rui Wu
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Margaret Dalrymple
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Mihir Chheda
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Donia Megahid
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Camila Arce
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Mingfang Shen
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Bhanu Dasari
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Xiaohui Zhao
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Maneesha Yalavarthi
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Pramod Rompikuntal
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Saravanan Ayyadurai
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Josephine Fang
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Alen Hozanovic
raw_affiliation_strings: Baxalta Innovations GmbH, a Part of Takeda Companies, Orth, Austria
raw_author_name: Brian Pescatore
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Dany Bassous
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Alla Romashko
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Elizabeth Galbreath
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Andreas Maccani
raw_affiliation_strings: Baxalta Innovations GmbH, a Part of Takeda Companies, Orth, Austria
raw_author_name: Julia Steinkellner
raw_affiliation_strings: Baxalta Innovations GmbH, a Part of Takeda Companies, Orth, Austria
raw_author_name: David E. Ehmann
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Vivian W. Choi
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
raw_author_name: Rizwana Islam
raw_affiliation_strings: Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA