CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia
Year: 2025
Type: article
Language: en
Topic: Advanced Breast Cancer Therapies
Authors and affiliations:
raw_author_name: Melissa L. Stewart
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Jessica Gibbs
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Kevin Watanabe-Smith
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Ariel Nguyen
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Isabel Kenna
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Karina Thiel-Klare
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Andy Kaempf
raw_affiliation_strings: Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Biostatistics Shared Resource, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Daniel Bottomly
raw_affiliation_strings: Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Stephen E. Kurtz
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Christopher A. Eide
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Nicola Long
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Jennifer N. Saultz
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Luca Sax
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Ariane Huang
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA
raw_author_name: Shannon K. McWeeney
raw_affiliation_strings: Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Division of Bioinformatics and Computational Biology, Department of Medical Informatics and Clinical Epidemiology, Oregon Health and Science University, Portland, OR, USA; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Bill H. Chang
raw_affiliation_strings: Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Division of Hematology and Oncology, Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA
raw_author_name: Jeffrey W. Tyner
raw_affiliation_strings: Division of Hematology and Medical Oncology, Oregon Health and Science University, Portland, OR, USA; Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA; Department of Cell, Developmental and Cancer Biology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA. Electronic address: tynerj@ohsu.edu