Clinical Frailty Scale as a Predictor of Early Treatment Discontinuation in Elderly Patients With Chronic Lymphocytic Leukemia Treated With Zanubrutinib: A Multicenter Real‐World Study
Year: 2025
Type: article
Language: en
Topic: Chronic Lymphocytic Leukemia Research
Authors and affiliations:
raw_author_name: Ernesto Vigna
raw_affiliation_strings: Department of Onco‐Hematology Hematology Unit Azienda Ospedaliera Annunziata  Cosenza Italy
raw_author_name: Enrica Antonia Martino
raw_affiliation_strings: Department of Onco‐Hematology Hematology Unit Azienda Ospedaliera Annunziata  Cosenza Italy
raw_author_name: Annalisa Pitino
raw_affiliation_strings: Institute of Clinical Physiology (IFC‐CNR)  Rome Italy
raw_author_name: Raffaella Pasquale
raw_affiliation_strings: Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) SOC Clinica Ematologia  Udine Italy
raw_author_name: Isacco Ferrarini
raw_affiliation_strings: Department of Engineering for Innovation Medicine University of Verona  Verona Italy
raw_author_name: Riccardo Moia
raw_affiliation_strings: Division of Hematology Department of Translational Medicine Università del Piemonte Orientale  Novara Italy
raw_author_name: Andrea Visentin
raw_affiliation_strings: Hematology Unit Department of Medicine‐DIMED University of Padova  Padova Italy
raw_author_name: Alessandro Sanna
raw_affiliation_strings: Hematology Unit Deparment of Oncology AOU‐Careggi  Florence Italy
raw_author_name: Marina Motta
raw_affiliation_strings: Department of Hematology ASST Spedali Civili di Brescia  Lombardia Italy
raw_author_name: Massimo Moratti
raw_affiliation_strings: Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) SOC Clinica Ematologia  Udine Italy
raw_author_name: Paolo Sportoletti
raw_affiliation_strings: Centro di Ricerca Emato‐Oncologica (CREO) Dipartimento di Medicina e Chirurgia Università di Perugia  Perugia Italy
raw_author_name: Annalisa Chiarenza
raw_affiliation_strings: Division of Hematology Azienda Policlinico‐S. Marco University of Catania  Catania Italy
raw_author_name: Alessandro Maggi
raw_affiliation_strings: Haematology Ospedale G. Moscati  Taranto Italy
raw_author_name: Valentina Zammit
raw_affiliation_strings: Oncoematology and BMT Unit Oncology Department Ospedale La Maddalena Palermo  Palermo Italy
raw_author_name: Michele Merli
raw_affiliation_strings: Hematology Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico  Milano Italy
raw_author_name: Idanna Innocenti
raw_affiliation_strings: Dipartimento di Scienze di Laboratorio ed Ematologiche Area Ematologia Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore  Rome Italy
raw_author_name: Claudia Giordano
raw_affiliation_strings: Department of Clinical Medicine and Surgery Federico II University Medical School  Naples Italy
raw_author_name: Laura Nocilli
raw_affiliation_strings: Department of Hematology Azienda Ospedaliera Papardo  Messina Italy
raw_author_name: Massimiliano Postorino
raw_affiliation_strings: Hematology Department of Biomedicine and Prevention Tor Vergata University of Rome  Rome Italy
raw_author_name: Caterina Stelitano
raw_affiliation_strings: Department of Hematology Azienda Ospedaliera Bianchi Melacrino Morelli  Reggio Calabria Italy
raw_author_name: Andrea Ferrario
raw_affiliation_strings: Department of Medicine and Surgery University of Insubria and Department of Oncology ASST Sette Laghi Ospedale di Circolo  Varese Italy
raw_author_name: Anna Maria Frustaci
raw_affiliation_strings: Department of Haematology Niguarda Cancer Center ASST Grande Ospedale Metropolitano Niguarda  Milan Italy
raw_author_name: Marcello Riva
raw_affiliation_strings: Hematology Department Ospedale San Bortolo di Vicenza  Vicenza Italy
raw_author_name: Sara Pepe
raw_affiliation_strings: Hematology Department of Translational and Precision Medicine Sapienza University  Rome Italy
raw_author_name: Adalberto Ibatici
raw_affiliation_strings: Hematology and Cellular Therapy Unit IRCCS Ospedale Policlinico San Martino  Genoa Italy
raw_author_name: Stefania Scardino
raw_affiliation_strings: Hematology and Stem Cell Transplant Unit “Vito Fazzi” Hospital  Lecce Italy
raw_author_name: Paola Anticoli Borza
raw_affiliation_strings: UOC Ematologia Azienda Ospedaliera San Giovanni‐Addolorata  Rome Italy
raw_author_name: Laura Ballotta
raw_affiliation_strings: Dipartimento Clinico di Scienze Mediche Chirurgiche e della Salute Università degli Studi di Trieste  Trieste Italy
raw_author_name: Salvatrice Mancuso
raw_affiliation_strings: Department of Health Promotion Mother and Child Care Internal Medicine and Medical Specialties (PROMISE) Hematology Unit University of Palermo  Palermo Italy
raw_author_name: Francesco Malaspina
raw_affiliation_strings: Hematology Unit IRCCS IRST Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori “Dino Amadori”  Meldola Italy
raw_author_name: Anna Mele
raw_affiliation_strings: Haematology Ospedale Cardinale Panico  Tricase(Lecce) Italy
raw_author_name: Sara Galimberti
raw_affiliation_strings: Division of Hematology University Hospital of Pisa  Pisa Italy
raw_author_name: Gioacchino Catania
raw_affiliation_strings: SCDU Ematologia ‐AOU SS Antonio e Biagio e C. Arrigo.  Alessandria Italy
raw_author_name: Annamaria Giordano
raw_affiliation_strings: Unit of Hematology and Stem Cell Transplantation AOUC Policlinico  Bari Italy
raw_author_name: Ilaria Angeletti
raw_affiliation_strings: Department of Medicine and Surgery University of Perugia Hematology/Oncology Unit Terni Hospital  Terni Italy
raw_author_name: Luana Schiattone
raw_affiliation_strings: Dipartimento di Ematologia Clinica Ospedale civile S. Spirito Pescara  Pescara Italy
raw_author_name: Elsa Pennese
raw_affiliation_strings: Dipartimento di Ematologia Clinica Ospedale civile S. Spirito Pescara  Pescara Italy
raw_author_name: Rosanna Miccolis
raw_affiliation_strings: Department of Hematology ASL BT  Barletta Italy
raw_author_name: Angelo Fama
raw_affiliation_strings: Department of Internal Medicine Hematology Unit Ospedale G. Mazzini  Teramo Italy
raw_author_name: Giulio Giordano
raw_affiliation_strings: Unità Operativa Complessa Medicina Servizio e Ambulatorio di Ematologia Ospedale di Riferimento Regionale Antonio Cardarelli  Campobasso Italy
raw_author_name: Catello Califano
raw_affiliation_strings: Onco‐Hematology Unit “A. Tortora” Hospital  Pagani Italy
raw_author_name: Antonella Bruzzese
raw_affiliation_strings: Department of Onco‐Hematology Hematology Unit Azienda Ospedaliera Annunziata  Cosenza Italy
raw_author_name: Santino Caserta
raw_affiliation_strings: Department of Onco‐Hematology Hematology Unit Azienda Ospedaliera Annunziata  Cosenza Italy
raw_author_name: Giuliana Farina
raw_affiliation_strings: Hematology Hospital “Sant'Anna e San Sebastiano”  Caserta Italy
raw_author_name: Pietro Bulian
raw_affiliation_strings: Centro di Riferimento Oncologico di Aviano (CRO) Clinical and Experimental Onco‐Hematology Unit IRCCS  Aviano Italy
raw_author_name: Giacomo Loseto
raw_affiliation_strings: Hematology and Cell Therapy Unit IRCCS Istituto Tumori ‘Giovanni Paolo II’  Bari Italy
raw_author_name: Barbara Pocali
raw_affiliation_strings: Division of Hematology and Stem Cell Transplantation Unit Cardarelli Hospital  Naples Italy
raw_author_name: Vanessa Innao
raw_affiliation_strings: Hematology Unit Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi  Catania Italy
raw_author_name: Piero Galieni
raw_affiliation_strings: Department of Haematology and Stem Cell Transplantation Unit C. e G. Mazzoni Hospital  Ascoli Piceno Italy
raw_author_name: Vincenzo Fraticelli
raw_affiliation_strings: Department of Hematology Gemelli Molise  Campobasso Italy
raw_author_name: Candida Vitale
raw_affiliation_strings: Department of Molecular Biotechnology and Health Sciences University of Turin  Turin Italy
Division of Hematology A.O.U. Città della Salute e della Scienza di Torino  Turin Italy
raw_author_name: Azzurra Romeo
raw_affiliation_strings: Hematology Unit Ospedale Santa Maria Goretti  Latina Italy
raw_author_name: Marco Rossi
raw_affiliation_strings: Department of Experimental and Clinical Medicine Magna Grecia University  Catanzaro Italy
Department of Hematology‐Oncology Azienda Universitaria Ospedaliera Renato Dulbecco  Catanzaro Italy
raw_author_name: Ilaria Scortechini
raw_affiliation_strings: Azienda Ospedaliero Universitaria delle Marche  Ancona Italy
raw_author_name: Federico Vozella
raw_affiliation_strings: Hematology Stem cell Transplantation Fondazione Policlinico Universitario Campus Bio Medico di Roma  Rome Italy
raw_author_name: Luigi Malandruccolo
raw_affiliation_strings: Hematology Unit Ospedale “Fabrizio Spaziani”  Frosinone Italy
raw_author_name: Marzia Varettoni
raw_affiliation_strings: Division of Hematology Fondazione IRCCS Policlinico San Matteo di Pavia  Pavia Italy
raw_author_name: Lucia Morello
raw_affiliation_strings: Unità Operativa di Ematologia Ospedale Guglielmo da Saliceto  Piacenza Italy
raw_author_name: Giuseppe Pietrantuono
raw_affiliation_strings: IRCCS CROB Referral Cancer Center of Basilicata  Rionero in Vulture Italy
raw_author_name: Esmeralda Conte
raw_affiliation_strings: Haematology Unit Department of Clinical and Molecular Medicine Sant'Andrea University Hospital Sapienza University  Rome Italy
raw_author_name: Martina Cantelli
raw_affiliation_strings: Unità di Ematologia Ospedale Santa Maria delle Croci  Ravenna Italy
raw_author_name: Roberta Murru
raw_affiliation_strings: Hematology and Stem Cell Transplantation Unit Ospedale Oncologico A. Businco ARNAS G. Brotzu  Cagliari Italy
raw_author_name: Daniele Caracciolo
raw_affiliation_strings: Department of Experimental and Clinical Medicine Magna Grecia University  Catanzaro Italy
raw_author_name: Enrico Derenzini
raw_affiliation_strings: Division of Onco‐Hematology IEO European Institute of Oncology IRCCS  Milano Italy
raw_author_name: Valentina Di Martina
raw_affiliation_strings: Hematology Unit Ospedale San Vincenzo  Taormina Italy
raw_author_name: Roberto Marasca
raw_affiliation_strings: Hematology Unit Department of Oncology and Hematology Azienda‐Ospedaliero Universitaria (AOU) of Modena Policlinico Modena  Modena Italy
raw_author_name: Maria Ilaria Del Principe
raw_affiliation_strings: Hematology Department of Biomedicine and Prevention Tor Vergata University of Rome  Rome Italy
raw_author_name: Amalia Figuera
raw_affiliation_strings: Division of Hematology Azienda Policlinico‐S. Marco University of Catania  Catania Italy
raw_author_name: Francesco Angotzi
raw_affiliation_strings: Hematology Unit Department of Medicine‐DIMED University of Padova  Padova Italy
raw_author_name: Marta Coscia
raw_affiliation_strings: Department of Medicine and Surgery University of Insubria and Department of Oncology ASST Sette Laghi Ospedale di Circolo  Varese Italy
raw_author_name: Nicola Di Renzo
raw_affiliation_strings: Hematology and Stem Cell Transplant Unit “Vito Fazzi” Hospital  Lecce Italy
raw_author_name: Luca Laurenti
raw_affiliation_strings: Dipartimento di Scienze di Laboratorio ed Ematologiche Area Ematologia Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore  Rome Italy
raw_author_name: Nicola Amodio
raw_affiliation_strings: Department of Experimental and Clinical Medicine Magna Grecia University  Catanzaro Italy
raw_author_name: Pellegrino Musto
raw_affiliation_strings: Department of Precision and Regenerative Medicine and Ionian Area “Aldo Moro” University School of Medicine  Bari Italy
Unit of Hematology and Stem Cell Transplantation AOUC Policlinico  Bari Italy
raw_author_name: Francesco Di Raimondo
raw_affiliation_strings: Division of Hematology Azienda Policlinico‐S. Marco University of Catania  Catania Italy
raw_author_name: Arcangelo Liso
raw_affiliation_strings: Department of Medicine and Surgery University of Perugia Hematology/Oncology Unit Terni Hospital  Terni Italy
raw_author_name: Alessandra Tedeschi
raw_affiliation_strings: Department of Haematology Niguarda Cancer Center ASST Grande Ospedale Metropolitano Niguarda  Milan Italy
raw_author_name: Livio Trentin
raw_affiliation_strings: Hematology Unit Department of Medicine‐DIMED University of Padova  Padova Italy
raw_author_name: Gianluca Gaidano
raw_affiliation_strings: Division of Hematology Department of Translational Medicine Università del Piemonte Orientale  Novara Italy
raw_author_name: Francesca Romana Mauro
raw_affiliation_strings: Hematology Department of Translational and Precision Medicine Sapienza University  Rome Italy
raw_author_name: Giovanni Tripepi
raw_affiliation_strings: Clinical Epidemiology and Physiopathology of Renal Diseases and Hypertension of Reggio Calabria Institute of Clinical Physiology (IFC‐CNR)  Reggio Calabria Italy
raw_author_name: Andrea Corsonello
raw_affiliation_strings: Department of Pharmacy Health and Nutritional Science University of Calabria  Rende Italy
Unit of Geriatric Medicine Italian National Research Center on Aging (IRCCS INRCA)  Cosenza Italy
raw_author_name: Fortunato Morabito
raw_affiliation_strings: AIL Sezione di Cosenza  Cosenza Italy
raw_author_name: Valter Gattei
raw_affiliation_strings: Centro di Riferimento Oncologico di Aviano (CRO) Clinical and Experimental Onco‐Hematology Unit IRCCS  Aviano Italy
raw_author_name: Massimo Gentile
raw_affiliation_strings: Department of Onco‐Hematology Hematology Unit Azienda Ospedaliera Annunziata  Cosenza Italy
Department of Pharmacy Health and Nutritional Science University of Calabria  Rende Italy