Causal neurodevelopmental origins of scoliosis: Multi-omics Mendelian randomization reveals brain–region–specific pathways and protein mediators
Year: 2025
Type: article
Language: en
Topic: Scoliosis diagnosis and treatment
Authors and affiliations:
raw_author_name: Shuhao Zhang
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Sisi Lu
raw_affiliation_strings: The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
raw_author_name: Shiyu Chen
raw_affiliation_strings: The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
raw_author_name: Xiangxiang Pan
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Dongdong Xia
raw_affiliation_strings: Orthopedic Department, Ningbo No.1 Hospital, Ningbo, Zhejiang, China
raw_author_name: Lue Liu
raw_affiliation_strings: Orthopedic Department, Ruian People's Hospital, Wenzhou, Zhejiang, China
raw_author_name: Chenglong Xie
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Majid Nisar
raw_affiliation_strings: Orthopedic Department, Swat Medical College and Swat Medical Complex Teaching Hospital, Khyber Pakhtunkhwa, Pakistan
raw_author_name: Aimin Wu
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, China
The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Xiaolei Zhang
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Xiangyang Wang
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, China
The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China
raw_author_name: Chongan Huang
raw_affiliation_strings: Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, China
The Second Medical School of Wenzhou Medical University, Wenzhou, Zhejiang, China
Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang, China