Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction–associated steatohepatitis in mice
Year: 2025
Type: article
Language: en
Topic: Drug Transport and Resistance Mechanisms
Authors and affiliations:
raw_author_name: Veronia Basaly
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Zakiyah R. Henry
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Rulaiha E. Taylor
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Bo Kong
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Ill Yang
raw_affiliation_strings: Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey
raw_author_name: Anita Brinker
raw_affiliation_strings: Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey
raw_author_name: Zhenning Yang
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Peihong Zhou
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey
raw_author_name: Laurie B. Joseph
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Lauren Aleksunes
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey
raw_author_name: Brian Buckley
raw_affiliation_strings: Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey
raw_author_name: Masahiko Negishi
raw_affiliation_strings: Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Chapel Hill, North Carolina
raw_author_name: Grace L. Guo
raw_affiliation_strings: Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey; Environmental and Occupational Health Science Institute, Rutgers University, Piscataway, New Jersey; Rutgers Center for Lipid Research, Rutgers University, New Brunswick, New Jersey; Department of Veterans Affairs New Jersey Health Care System, East Orange, New Jersey. Electronic address: glg48@eohsi.rutgers.edu