UBE2K promotes breast cancer growth by ubiquitinating and degrading STUB1 to regulate the PKA/CREB1 signaling pathway, forming a feedback loop
Year: 2025
Type: article
Language: en
Topic: Ubiquitin and proteasome pathways
Authors and affiliations:
raw_author_name: Jiancheng Mou
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Hongchao Tang
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China; Key Laboratory for Diagnosis and Treatment of Upper Limb Edema and Stasis of Breast Cancer, Hangzhou, 310053, Zhejiang, China
raw_author_name: Xiaoge Hu
raw_affiliation_strings: Zhejiang Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China
raw_author_name: Zhuotao Yang
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Haotian Su
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Da Qian
raw_affiliation_strings: Central Laboratory, Changshu Hospital Affiliated to Soochow University, Changshu No.1 People's Hospital, Changshu, 215500, China
raw_author_name: Chenhong Li
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Haotian Liu
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Zhihao Ye
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Mingxing Xu
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Shuyan Liu
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Qinghui Zheng
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Xiaozhen Liu
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China; Key Laboratory for Diagnosis and Treatment of Upper Limb Edema and Stasis of Breast Cancer, Hangzhou, 310053, Zhejiang, China
raw_author_name: Xin Zeng
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China
raw_author_name: Qiuran Xu
raw_affiliation_strings: Zhejiang Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, 310014, China. Electronic address: xuqiuran@hmc.edu.cn
raw_author_name: Xuli Meng
raw_affiliation_strings: Department of Breast Surgery, General Surgery, Cancer Center, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, 310053, Zhejiang, China; Key Laboratory for Diagnosis and Treatment of Upper Limb Edema and Stasis of Breast Cancer, Hangzhou, 310053, Zhejiang, China. Electronic address: mxlmail@126.com