Bringing tuberculosis genomics to the clinic: development and validation of a comprehensive pipeline to predict antimicrobial susceptibility from genomic data, accredited to ISO standards
Year: 2025
Type: article
Language: en
Topic: Tuberculosis Research and Epidemiology
Authors and affiliations:
raw_author_name: Kristy A Horan
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Linda Viberg
raw_affiliation_strings: Mycobacterium Reference Laboratory, Victorian Infectious Diseases Reference Laboratory (VIDRL), at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Susan A Ballard
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Maria Globan
raw_affiliation_strings: Mycobacterium Reference Laboratory, Victorian Infectious Diseases Reference Laboratory (VIDRL), at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Wytamma Wirth
raw_affiliation_strings: Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology, Royal Melbourne Hospital, Melbourne, VIC, Australia
raw_author_name: Katherine Bond
raw_affiliation_strings: Mycobacterium Reference Laboratory, Victorian Infectious Diseases Reference Laboratory (VIDRL), at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology, Royal Melbourne Hospital, Melbourne, VIC, Australia
raw_author_name: Jessica R Webb
raw_affiliation_strings: Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; School of Biological Sciences, University of Adelaide, Adelaide, SA, Australia
raw_author_name: Thinley Dorji
raw_affiliation_strings: Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Deborah A Williamson
raw_affiliation_strings: Mycobacterium Reference Laboratory, Victorian Infectious Diseases Reference Laboratory (VIDRL), at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia
raw_author_name: Michelle L Sait
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Ee Laine Tay
raw_affiliation_strings: Communicable Disease Epidemiology and Surveillance, Health Protection Branch, Public Health Division, Department of Health, Melbourne, VIC, Australia
raw_author_name: Justin T Denholm
raw_affiliation_strings: Victorian Tuberculosis Program, Melbourne Health at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia
raw_author_name: Benjamin P Howden
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology, Royal Melbourne Hospital, Melbourne, VIC, Australia; Centre for Pathogen Genomics, The University of Melbourne, Melbourne, VIC, Australia; Department of Infectious Diseases & Immunology, Austin Health, Heidelberg, VIC, Australia. Electronic address: bhowden@unimelb.edu.au
raw_author_name: Torsten Seemann
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Centre for Pathogen Genomics, The University of Melbourne, Melbourne, VIC, Australia
raw_author_name: Norelle L Sherry
raw_affiliation_strings: Microbiological Diagnostic Unit Public Health Laboratory (MDU PHL), Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia; Centre for Pathogen Genomics, The University of Melbourne, Melbourne, VIC, Australia; Department of Infectious Diseases & Immunology, Austin Health, Heidelberg, VIC, Australia