Targeting ALC1 can safely expand the therapeutic utility of PARP inhibitors across high-grade serous ovarian cancers
Year: 2025
Type: article
Language: en
Topic: PARP inhibition in cancer therapy
Authors and affiliations:
raw_author_name: Lindsey N. Aubuchon
raw_affiliation_strings: Cancer Biology Graduate Program, Washington University School of Medicine; St. Louis, MO, 63110, USA
Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Deanna H. Wong
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University; St. Louis, Missouri, USA
Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Natasha M. Ramakrishnan
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Samantha F. Greenberg
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Rohan Reddy
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Elena Lomonosova
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University; St. Louis, Missouri, USA
raw_author_name: Amanda Compadre
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University; St. Louis, Missouri, USA
raw_author_name: Kathleen E. Jackson
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Danielle Kemper
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Vrutti Mehta
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Kellen Zoberi
raw_affiliation_strings: Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA
raw_author_name: Dineo Khabele
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University; St. Louis, Missouri, USA
raw_author_name: Elizabeth L. Christie
raw_affiliation_strings: Sir Peter MacCallum Department of Oncology, The University of Melbourne; Parkville, Victoria, Australia
raw_author_name: Mary M. Mullen
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University; St. Louis, Missouri, USA
raw_author_name: Priyanka Verma
raw_affiliation_strings: Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Siteman Cancer Center, Washington University School of Medicine; 4911 Barnes Jewish Hospital Plaza, St. Louis, Missouri 63110, USA
Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine; St. Louis, MO, 63110, USA