Ligand non-competitive GITR antibody prevents formation of the obligatory signal-triggering GITRL: GITR stoichiometry
Year: 2025
Type: article
Language: en
Topic: T-cell and B-cell Immunology
Authors and affiliations:
raw_author_name: Jing Yan
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Jessica Min-DeBartolo
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Ching-Shin Huang
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: M. Nusrat Sharif
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Li Li
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Susan Fish
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Corey Dower
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Denise Murphy
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Tatyana Andreyeva
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Heng Liu
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Xinbing Han
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Wei Zheng
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Jot Hui Ooi
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Jason Edmonds
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Ting Chen
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Zachary Maben
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Chad R. Stevens
raw_affiliation_strings: Pharmacokinetics, Dynamics & Metabolism (PDM), Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Andover, MA, USA
raw_author_name: Polina Goihberg
raw_affiliation_strings: Pharmacokinetics, Dynamics & Metabolism (PDM), Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Andover, MA, USA
raw_author_name: Malgorzata Nocula-Lugowska
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Steven M Evans
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Lidia Mosyak
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Kerry Kelleher
raw_affiliation_strings: BioMedicine Design, Preclinical and Translational Sciences, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Caitlyn Dickinson
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Martin Hegen
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Aaron Winkler
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA
raw_author_name: Fridrik Karlsson
raw_affiliation_strings: Inflammation and Immunology Research Unit, Pfizer Research & Development, Pfizer Inc., Cambridge, MA, USA. fridrikj.karlsson@pfizer.com