Synthesis and identification of a novel selective USP7 degrader that inhibits the migration of upper gastrointestinal cancer cells without affecting proliferation
Year: 2025
Type: article
Language: en
Topic: Protein Degradation and Inhibitors
Authors and affiliations:
raw_author_name: Xu-bin Ma
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Kai Sun
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Yuan-yuan Liu
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Liang Wang
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Chen-ran Lu
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Mo-han Li
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Zhuang-zhuang Li
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China
raw_author_name: Hong-min Liu
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China. Electronic address: liuhm@zzu.edu.cn
raw_author_name: Yi-chao Xu
raw_affiliation_strings: Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Henan Province Key Laboratory of Small Molecule Drug Discovery and Applied Research, School of Pharmaceutical Sciences, Zhengzhou University, 100 Science Avenue, Zhengzhou, 450001, China. Electronic address: xuyc2017@zzu.edu.cn