Propranolol metabolite and enantiomers affect colorectal cancer development by inhibiting MAPK pathway and downregulating PD-1 expression
Year: 2025
Type: article
Language: en
Topic: Cancer, Stress, Anesthesia, and Immune Response
Authors and affiliations:
raw_author_name: Hanying Yi
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Yingying Dai
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Cuiyu Chen
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Wenjuan Ma
raw_affiliation_strings: Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Yu Zhang
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Shiyu Wang
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Ouyang Jing
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Dongbo Liu
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Jielin Wan
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Yang Wang
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Jie Liu
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Howard L. Mcleod
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; Intermountain Precision Genomics, Intermountain healthcare, St. George UT84770, USA
raw_author_name: Lin Chen
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address: chendoc@126.com
raw_author_name: Yijing He
raw_affiliation_strings: Department of Clinical Pharmacology, Xiangya Hospital, Central South University, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address: heyijing@csu.edu.cn