Manganese-enriched nanoboron agent amplifies BNCT efficacy via pyroptosis-mediated immune activation and STING pathway synergy
Year: 2025
Type: article
Language: en
Topic: Boron Compounds in Chemistry
Authors and affiliations:
raw_author_name: Zhicheng Zhang
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China
Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310058, China
raw_author_name: Xiaoyan Sun
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China
raw_author_name: Yaxin Qin
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China
Jinhua Institute of Zhejiang University, Jinhua, 321299, China
raw_author_name: Yufan Yang
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China
raw_author_name: Qi Dai
raw_affiliation_strings: Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310058, China
raw_author_name: Xiaoyan Bao
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China
raw_author_name: Minoru Suzuki
raw_affiliation_strings: Division of Particle Radiation Oncology, Particle Radiation Oncology Research Center, Institute for Integrated Radiation and Nuclear Science, Kyoto University, 2- 1010, Asashiro-Nishi, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan
raw_author_name: Sheng Wang
raw_affiliation_strings: Department of Nuclear Science and Technology, School of Energy and Power Engineering, Xi'an Jiaotong University, No. 28, Xianning West Road, Xi'an, 710049, Shaanxi, China
raw_author_name: Zai Yang
raw_affiliation_strings: Department of Nuclear Science and Technology, School of Energy and Power Engineering, Xi'an Jiaotong University, No. 28, Xianning West Road, Xi'an, 710049, Shaanxi, China
raw_author_name: Zhifeng Li
raw_affiliation_strings: Department of Nuclear Science and Technology, School of Energy and Power Engineering, Xi'an Jiaotong University, No. 28, Xianning West Road, Xi'an, 710049, Shaanxi, China
raw_author_name: Min Han
raw_affiliation_strings: College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China. hanmin@zju.edu.cn
Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310058, China. hanmin@zju.edu.cn
Hangzhou Institute of Innovative Medicine, Zhejiang University, Hangzhou, 310058, China. hanmin@zju.edu.cn
Jinhua Institute of Zhejiang University, Jinhua, 321299, China. hanmin@zju.edu.cn
raw_author_name: Donghang Xu
raw_affiliation_strings: Department of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, 310058, China. xudonghang@zju.edu.cn
raw_author_name: Qichun Wei
raw_affiliation_strings: Department of Radiation Oncology, Key Laboratory of Cancer Prevention and Intervention, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310058, China. qichun_wei@zju.edu.cn