TGF-βRII/IL-15 immunotherapeutic complex targets exhausted CD8 <sup>+</sup> T-cell subsets in lymph nodes and tumors
Year: 2025
Type: article
Language: en
Topic: Cancer Immunotherapy and Biomarkers
Authors and affiliations:
raw_author_name: Varghese K George
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Hing C Wong
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Martin Felices
raw_affiliation_strings: Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
raw_author_name: Mark P Rubinstein
raw_affiliation_strings: Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
Department of Surgery, Ohio State University Health System, Columbus, Ohio, USA
raw_author_name: Niraj Shrestha
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Natalia Valderrama
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Hamidreza Farzaneh
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Lin Kong
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Crystal Gilkes
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Alyssa Thompson
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Megan Larson
raw_affiliation_strings: Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
raw_author_name: Bai Liu
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Xiaoyun Zhu
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Gilles Michel Leclerc
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Dongjun Chung
raw_affiliation_strings: Department of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, Ohio, USA
Pelotonia Institute for Immuno-Oncology, Arthur G James Cancer Hospital and Richard J Solove Research Institute, Columbus, Ohio, USA
raw_author_name: Juan Xie
raw_affiliation_strings: Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
raw_author_name: Jordan Krull
raw_affiliation_strings: Department of Biomedical Informatics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
Pelotonia Institute for Immuno-Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
raw_author_name: Lucas Gomez
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Leah Kanakaraj
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Ann Bialik
raw_affiliation_strings: University of Miami Leonard M Miller School of Medicine, Miami, Florida, USA
raw_author_name: Jack O Egan
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Lijing You
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Xianglan Liu
raw_affiliation_strings: Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
raw_author_name: Rachael Teodorescu
raw_affiliation_strings: Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA
raw_author_name: Ana K Karen Gutierrez
raw_affiliation_strings: The Ohio State University, Columbus, Ohio, USA
raw_author_name: Christian Echeverri
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Reynier Rodriguez
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Zheng Wang
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Jilan Xing
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Neicy Gonzalez
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Pallavi Chaturvedi
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Manish R Patel
raw_affiliation_strings: Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
raw_author_name: Rose Wangen
raw_affiliation_strings: Obstetrics, Gynecology and Women’s Health, University of Minnesota, Minneapolis, Minnesota, USA
raw_author_name: Qing Cao
raw_affiliation_strings: University of Minnesota System, Minneapolis, Minnesota, USA
raw_author_name: Peter R Rhode
raw_affiliation_strings: HCW Biologics Inc, Miramar, Florida, USA
raw_author_name: Jeffrey S Miller
raw_affiliation_strings: Department of Medicine, University of Minnesota, Minneapolis, Minnesota, USA
raw_author_name: Melissa A Geller
raw_affiliation_strings: Obstetrics, Gynecology and Women’s Health, University of Minnesota, Minneapolis, Minnesota, USA