Sitravatinib plus tislelizumab in locally recurrent or metastatic triple-negative breast cancer: a multi-cohort, single-arm, phase II clinical trial (SPARK Trial)
Year: 2025
Type: article
Language: en
Topic: Phagocytosis and Immune Regulation
Authors and affiliations:
raw_author_name: Xi-Yu Liu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Xin-Yi Sui
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Ying Xu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Fan Yang
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Song-Yang Wu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Xiu-Zhi Zhu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Ke Zuo
raw_affiliation_strings: Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China
raw_author_name: Shuo-Wen Cao
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Xi Jin
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Li Chen
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Lin-Xiaoxi Ma
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Wen-Juan Zhang
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Fu-Gui Ye
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Fei-Lin Qu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Ding Ma
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Yi Xiao
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Gen-Hong Di
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Guang-Yu Liu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Ke-Da Yu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Jiong Wu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Xin Hu
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Yi-Zhou Jiang
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China
raw_author_name: Zhong-Hua Wang
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China. zhonghuawang95@hotmail.com
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. zhonghuawang95@hotmail.com
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China. zhonghuawang95@hotmail.com
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
raw_author_name: Zhi-Ming Shao
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China. zhimingshao@fudan.edu.cn
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. zhimingshao@fudan.edu.cn
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China. zhimingshao@fudan.edu.cn
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China
raw_author_name: Lei Fan
raw_affiliation_strings: Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China. teddyfl@163.com
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. teddyfl@163.com
Fudan University Shanghai Cancer Center and Key Laboratory of Breast Cancer, Shanghai, China. teddyfl@163.com
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China
Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, China