Single-Particle Multiparametric Microscopy Reveals Structural, Size, and Payload Heterogeneity in mRNA-Loaded Lipid Nanoparticles
Year: 2025
Type: article
Language: en
Topic: RNA Interference and Gene Delivery
Authors and affiliations:
raw_author_name: Albert Kamanzi
raw_affiliation_strings: Department of Physics and Astronomy
Michael Smith Laboratories
ScopeSys, Inc., 2366 Main Mall, Vancouver, BC V6T 1Z4, Canada
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Ariadne Tuckmantel Bido
raw_affiliation_strings: Michael Smith Laboratories
ScopeSys, Inc., 2366 Main Mall, Vancouver, BC V6T 1Z4, Canada
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Yao Zhang
raw_affiliation_strings: Department of Biochemistry and Molecular Biology
Michael Smith Laboratories
School of Biomedical Engineering
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Erik Olsén
raw_affiliation_strings: Department of Physics
Michael Smith Laboratories
University of British Columbia
University of Gothenburg
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Maya Stibbards-Lyle
raw_affiliation_strings: Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Martin Jasinski
raw_affiliation_strings: Department of Physics and Astronomy
Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Yifei Gu
raw_affiliation_strings: Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Benjamin Wang
raw_affiliation_strings: ScopeSys, Inc., 2366 Main Mall, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Michael Venier-Karzis
raw_affiliation_strings: ScopeSys, Inc., 2366 Main Mall, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Romain Berti
raw_affiliation_strings: ScopeSys, Inc., 2366 Main Mall, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Michelle Jeliazkova
raw_affiliation_strings: Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Cynthia Shaheen
raw_affiliation_strings: Department of Physics and Astronomy
Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Jerry Leung
raw_affiliation_strings: Department of Biochemistry and Molecular Biology
Michael Smith Laboratories
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada
raw_author_name: Miffy Hok Yan Cheng
raw_affiliation_strings: Department of Biochemistry and Molecular Biology
Faculty of Pharmaceutical Sciences
University of British Columbia
raw_author_name: Pieter R. Cullis
raw_affiliation_strings: Faculty of Pharmaceutical Sciences
University of British Columbia
raw_author_name: Sabrina Leslie
raw_affiliation_strings: Department of Physics and Astronomy
Michael Smith Laboratories
School of Biomedical Engineering
University of British Columbia
Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada