A BRN2:MYC transcriptional axis regulates interconversion between therapy-resistant and tumorigenic phenotypes in melanoma
Year: 2025
Type: article
Language: en
Topic: Melanoma and MAPK Pathways
Authors and affiliations:
raw_author_name: Yuntian Zhang
raw_affiliation_strings: Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
raw_author_name: Marcus A. Urquijo
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah School of Medicine, Salt Lake City, UT 84103, USA
raw_author_name: Rebecca G. Zitnay
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Molecular Genetics, The Ohio State University College of Arts and Sciences, Columbus, OH 43210, USA; Department of Chemical Engineering, University of Utah, Salt Lake City, UT 84103, USA
raw_author_name: Kayla Marks
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Rachel L. Belote
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Molecular Genetics, The Ohio State University College of Arts and Sciences, Columbus, OH 43210, USA
raw_author_name: Maike M.K. Hansen
raw_affiliation_strings: Radboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ Nijmegen, the Netherlands
raw_author_name: Montana Ferita
raw_affiliation_strings: Department of Mathematics, University of Utah, Salt Lake City, UT, USA
raw_author_name: Hannah M. Neuendorf
raw_affiliation_strings: Cancer Drug Mechanisms Group, Cancer Research Department, QIMR Berghofer, Brisbane, QLD 4006, Australia; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4059, Australia
raw_author_name: Tong Liu
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Eric A. Smith
raw_affiliation_strings: Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA
raw_author_name: Elnaz Mirzaei Mehrabad
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
raw_author_name: Miroslav Hejna
raw_affiliation_strings: Department of Physics, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
raw_author_name: Tarek E. Moustafa
raw_affiliation_strings: Department of Chemical Engineering, University of Utah, Salt Lake City, UT 84103, USA
raw_author_name: Devin Lange
raw_affiliation_strings: SCI Institute and Kahlert School of Computing, University of Utah, Salt Lake City, UT 84112, USA
raw_author_name: Min Hu
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah School of Medicine, Salt Lake City, UT 84103, USA
raw_author_name: Fatemeh Vand-Rajabpour
raw_affiliation_strings: Department of Medical Genetics, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
raw_author_name: Anne Done
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Carly A. Becker
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Matthew Lieberman
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA
raw_author_name: Matthew Chang
raw_affiliation_strings: Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA; Departments of Biomedical Engineering and Oncological Sciences, Oregon Health and Science University, Portland, OR 97239, USA; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Operative Care Division, VA Portland Health Care System, Portland, OR 97239, USA
raw_author_name: Brian K. Lohman
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
raw_author_name: Chris J. Stubben
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA
raw_author_name: Melissa Q. Reeves
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Pathology, University of Utah, Salt Lake City, UT 84132, USA
raw_author_name: Xiaoyang Zhang
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah School of Medicine, Salt Lake City, UT 84103, USA
raw_author_name: Leor S. Weinberger
raw_affiliation_strings: Gladstone Center for Cell Circuitry, Gladstone Institutes, San Francisco, CA 94158, USA; Departments of Pharmaceutical Chemistry and Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA
raw_author_name: Matthew W. VanBrocklin
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Dekker C. Deacon
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Douglas Grossman
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
raw_author_name: Benjamin T. Spike
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah School of Medicine, Salt Lake City, UT 84103, USA
raw_author_name: Alexander Lex
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; SCI Institute and Kahlert School of Computing, University of Utah, Salt Lake City, UT 84112, USA
raw_author_name: Glen M. Boyle
raw_affiliation_strings: Cancer Drug Mechanisms Group, Cancer Research Department, QIMR Berghofer, Brisbane, QLD 4006, Australia; School of Biomedical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, QLD 4059, Australia; School of Biomedical Science, Faculty of Health, Medicine and Behavioral Sciences, University of Queensland, Brisbane, QLD 4072, Australia
raw_author_name: Rajan Kulkarni
raw_affiliation_strings: Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA; Departments of Biomedical Engineering and Oncological Sciences, Oregon Health and Science University, Portland, OR 97239, USA; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Operative Care Division, VA Portland Health Care System, Portland, OR 97239, USA
raw_author_name: Thomas A. Zangle
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Chemical Engineering, University of Utah, Salt Lake City, UT 84103, USA
raw_author_name: Robert L. Judson-Torres
raw_affiliation_strings: Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA; Department of Oncological Sciences, University of Utah School of Medicine, Salt Lake City, UT 84103, USA; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA. Electronic address: robert.judson-torres@hci.utah.edu