TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer
Year: 2025
Type: article
Language: en
Topic: FOXO transcription factor regulation
Authors and affiliations:
raw_author_name: Junbing Chen
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Hepatobiliary Surgery &amp; Liver Transplantation Liver Cancer Institute Zhongshan Hospital Fudan University Key Laboratory of Carcinogenesis and Cancer Invasion Ministry of Education Shanghai 200032 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
Department of Hepatobiliary Surgery & Liver Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, 200032 China
raw_author_name: Longtao Huangfu
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Gangjian Wang
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Xueying Wang
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Huanbo Zhu
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Qian Yao
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Program in MPE Molecular Pathological Epidemiology Department of Pathology Brigham and Women's Hospital Harvard Medical School Boston MA 02215 USA
Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02215 USA
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Cong Chen
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Xiaohuan Tang
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Ting Guo
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Biao Fan
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Xingyang Liu
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Laboratory of Molecular Oncology Peking University Cancer Hospital &amp; Institute  Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Laboratory of Molecular Oncology, Peking University Cancer Hospital & Institute, Beijing, 100142 China
raw_author_name: Qingda Li
raw_affiliation_strings: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital and Institute Beijing 100142 China
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Zining Liu
raw_affiliation_strings: Department of Gynecologic Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences &amp; Peking Union Medical College Beijing 100021 China
Department of Gynecologic Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100021 China
raw_author_name: Ying Hu
raw_affiliation_strings: Biological Sample Bank Peking University Cancer Hospital &amp; Institute  Fu‐Cheng Road Beijing 100142 China
Biological Sample Bank, Peking University Cancer Hospital & Institute, Fu-Cheng Road, Beijing, 100142 China
raw_author_name: Tianze Sun
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, Beijing, 100142 China
raw_author_name: Jiafu Ji
raw_affiliation_strings: Department of Gastrointestinal Surgery Peking University Cancer Hospital and Institute Beijing 100142 China
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational Research Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital &amp; Institute  Beijing 100142 China
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital & Institute, Beijing, 100142 China
raw_author_name: Xiaofang Xing
raw_affiliation_strings: State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational Research Division of Gastrointestinal Cancer Translational Research Laboratory Peking University Cancer Hospital &amp; Institute  Beijing 100142 China
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Division of Gastrointestinal Cancer Translational Research Laboratory, Peking University Cancer Hospital & Institute, Beijing, 100142 China