Lymphodepleting chemotherapy potentiates neoantigen-directed T cell therapy by enhancing antigen presentation
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Shira Sagie
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel; Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel
raw_author_name: Tomer Babu
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Chen Weller
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Claire Tabachnik
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Ido Livneh
raw_affiliation_strings: Rappaport Technion Cancer Research center, The Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525433, Israel; Institute of Pathology, Rambam Health Care Campus, Haifa 3109601, Israel
raw_author_name: Nele P. Quast
raw_affiliation_strings: Department of Statistics, University of Oxford, OX1 3LB Oxford, UK
raw_author_name: Nofar Gumpert
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Alina Shomuradova
raw_affiliation_strings: Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK
raw_author_name: Matthew I. Raybould
raw_affiliation_strings: Department of Statistics, University of Oxford, OX1 3LB Oxford, UK
raw_author_name: Ronen Levy
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Dmitry Malko
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Adi Alfia
raw_affiliation_strings: Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Talal Ben Lulu
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Michal Alon
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Franco Herrera
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Mikhail Kutuzov
raw_affiliation_strings: Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK
raw_author_name: Mirie Zerbib
raw_affiliation_strings: Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Polina Greenberg
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Talya Wasserman-Bartov
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Gil Benedek
raw_affiliation_strings: Faculty of Medicine, Hadassah Hebrew-University Medical Center, Jerusalem 91120, Israel
raw_author_name: Yishai Levin
raw_affiliation_strings: INCPM, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Chani Stossel
raw_affiliation_strings: Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
raw_author_name: Iris Kamer
raw_affiliation_strings: Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
raw_author_name: Talia Golan
raw_affiliation_strings: Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
raw_author_name: Roni Oren
raw_affiliation_strings: Department of Veterinary Resources, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Merav Shmueli
raw_affiliation_strings: Department of Systems Immunology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Osnat Bartok
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel
raw_author_name: Jair Bar
raw_affiliation_strings: Jusidman Cancer Center, Sheba Medical Center, Ramat Gan 52621, Israel; Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
raw_author_name: Jonathan Cohen
raw_affiliation_strings: Sharett Institute of Oncology, Hadassah Cancer Research Institute and The Wohl Institute for Translational Medicine, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel
raw_author_name: Omer Dushek
raw_affiliation_strings: Sir William Dunn School of Pathology, University of Oxford, OX1 3RE Oxford, UK
raw_author_name: Charlotte M. Deane
raw_affiliation_strings: Department of Statistics, University of Oxford, OX1 3LB Oxford, UK
raw_author_name: Yardena Samuels
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: yardena.samuels@weizmann.ac.il