IL-21 attenuates liver inflammation by enhancing myeloid-derived suppressor cells immunosuppressive function in chronic HBV infection
Year: 2025
Type: article
Language: en
Topic: Immune cells in cancer
Authors and affiliations:
raw_author_name: Xiaoyi Li
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
raw_author_name: Zihan Jin
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
raw_author_name: Meihan Pan
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: Zheyu Dong
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: Junlin Chen
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
raw_author_name: Zhipeng Liu
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
raw_author_name: Hongjie Chen
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
raw_author_name: Guofu Ye
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: Shihong Zhong
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: Weiying He
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: Libo Tang
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China. tanglibosmu@foxmail.com
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment
raw_author_name: GuiRong Rao
raw_affiliation_strings: Central Laboratory of Air Force Hospital in the Southern Theater, Guangzhou, 510602, Guangdong Province, PR China. raogr@126.com
Central Laboratory of Air Force Hospital in the Southern Theater, Guangzhou, 510602, Guangdong Province, PR China
raw_author_name: Yongyin Li
raw_affiliation_strings: Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment; Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China. yongyinli@foxmail.com
Key Laboratory of Infectious Diseases Research in South China (Southern Medical University), Ministry of Education, Guangdong Provincial Key Laboratory for Prevention and Control of Major Liver Diseases, Guangdong Provincial Research Center for Liver Fibrosis Engineering and Technology, No.1838 North Guangzhou Avenue, Guangzhou, 510515, China
Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, State Key Laboratory of Multi-Organ Injury Prevention and Treatment