SGSS05-NS3, a covalent SETD8 inhibitor that activates p53 pathway in neuroblastoma
Year: 2025
Type: article
Language: en
Topic: Neuroblastoma Research and Treatments
Authors and affiliations:
raw_author_name: Zhihui Liu
raw_affiliation_strings: Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA
raw_author_name: Sukriti Bagchi
raw_affiliation_strings: Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA
raw_author_name: Chunhua Yan
raw_affiliation_strings: Center for Biomedical Informatics and Information Technology, Center for Cancer Research, National Cancer Institute, Rockville, MD, USA
raw_author_name: Ying Hu
raw_affiliation_strings: Center for Biomedical Informatics and Information Technology, Center for Cancer Research, National Cancer Institute, Rockville, MD, USA
raw_author_name: Gil Blum
raw_affiliation_strings: Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
Tri-Institutional PhD Program of Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
raw_author_name: Anqi Ma
raw_affiliation_strings: Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Oncological Sciences and Neuroscience, Tisch Cancer Institute, New York, NY, 10029, USA
raw_author_name: Jian Jin
raw_affiliation_strings: Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, Oncological Sciences and Neuroscience, Tisch Cancer Institute, New York, NY, 10029, USA
raw_author_name: Minkui Luo
raw_affiliation_strings: Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
Program of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY, 10021, USA
Tri-Institutional PhD Program of Chemical Biology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA
raw_author_name: Sebastiano Di Bella
raw_affiliation_strings: Department of Precision Medicine in Medical, Surgical and Critical Care, University of Palermo, Palermo, Italy
raw_author_name: Francesco Verona
raw_affiliation_strings: Department of Health Promotion Sciences, Internal Medicine and Medical Specialties, University of Palermo, Palermo, 90127, Italy
raw_author_name: Ettore Appella
raw_affiliation_strings: Chemical Immunology Section, Laboratory of Cell Biology, National Cancer Institute, Bethesda, MD, USA
raw_author_name: Giuseppe Giannini
raw_affiliation_strings: Department of Molecular Medicine, University of Rome La Sapienza, Rome, 00161, Italy
Istituto Pasteur-Fondazione Cenci Bolognetti, Rome, 00161, Italy
raw_author_name: Carol J. Thiele
raw_affiliation_strings: Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA. thielec@mail.nih.gov
Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA
raw_author_name: Veronica Veschi
raw_affiliation_strings: Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA. veronica.veschi@uniroma1.it
Department of Molecular Medicine, University of Rome La Sapienza, Rome, 00161, Italy. veronica.veschi@uniroma1.it
Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD, 20892, USA
Department of Molecular Medicine, University of Rome La Sapienza, Rome, 00161, Italy