Chondrosarcoma organoids reveal SHH pathway activation driven by PTCH1 and BCOR alterations
Year: 2025
Type: article
Language: en
Topic: Bone Tumor Diagnosis and Treatments
Authors and affiliations:
raw_author_name: Haruna Takami
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Keiichi Yoshida
raw_affiliation_strings: Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Next-generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Yukiko Matsuoka
raw_affiliation_strings: Next-generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Satoru Sasagawa
raw_affiliation_strings: Molecular Biology Laboratory, Research Institute, Nozaki Tokushukai Hospital, Tanigawa 2-10-50, Daito, Osaka, 574-0074, Japan
raw_author_name: Noriko Nagamine
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Yoji Kukita
raw_affiliation_strings: Laboratory of Genomic Pathology, Osaka International Cancer Institute, 3- 1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Kazuma Kiyotani
raw_affiliation_strings: Laboratory of Immunogenomics, Center for Intractable Diseases and ImmunoGenomics (CiDIG), Health and Nutrition (NIBIOHN), National Institute of Biomedical Innovation, Ibaraki-shi, Osaka, Japan
raw_author_name: Yusuke Yoshimura
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Rie Suzuki
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Hironari Tamiya
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Shigeki Kakunaga
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Toshinari Yagi
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Sho Nakai
raw_affiliation_strings: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Yoshinori Imura
raw_affiliation_strings: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Seiji Okada
raw_affiliation_strings: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Ken-ichi Yoshida
raw_affiliation_strings: Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Next-generation Precision Medicine Research Center, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
raw_author_name: Satoshi Takenaka
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
raw_author_name: Toru Wakamatsu
raw_affiliation_strings: Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan. evolutionhhh49@yahoo.co.jp
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. evolutionhhh49@yahoo.co.jp
Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan
Department of Musculoskeletal Oncology Service, Osaka International Cancer Institute, 3-1-69 Otemae, Chuo-ku, Osaka, 541-8567, Japan