Design and synthesis of novel fucosylated chondroitin sulfate derivatives as intrinsic FXase inhibitors and evaluation of their antithrombotic activities
Year: 2025
Type: article
Language: en
Topic: Proteoglycans and glycosaminoglycans research
Authors and affiliations:
raw_author_name: Dongliang Xu
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Xi Gong
raw_affiliation_strings: School of Traditional Chinese Pharmacy, Shenyang Pharmaceutical University, Shenyang, 117004, China; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
raw_author_name: Lisha Lin
raw_affiliation_strings: State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
raw_author_name: Hang Dong
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Yijian Wen
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Yingnian Li
raw_affiliation_strings: State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China
raw_author_name: Gang Fu
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Yuanhang Ma
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Weicheng Xiong
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Tianyu Guan
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Ao Sun
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Xiangbao Meng
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China
raw_author_name: Xudong Dong
raw_affiliation_strings: The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, 650032, China
raw_author_name: Zhongtang Li
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China; Ningbo Institute of Marine Medicine, Peking University, Ningbo, 315832, China. Electronic address: lizhongtang@bjmu.edu.cn
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China; Ningbo Institute of Marine Medicine, Peking University, Ningbo, 315832, China. Electronic address: zjli@bjmu.edu.cn
raw_author_name: Mingyi Wu
raw_affiliation_strings: State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. Electronic address: wumingyi@mail.kib.ac.cn
raw_author_name: Zhongjun Li
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China; Ningbo Institute of Marine Medicine, Peking University, Ningbo, 315832, China. Electronic address: lizhongtang@bjmu.edu.cn
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China; Ningbo Institute of Marine Medicine, Peking University, Ningbo, 315832, China. Electronic address: zjli@bjmu.edu.cn