MEK inhibitor induces cardiac complications by preventing ZMYND8-mediated ubiquitination and proteasomal degradation of HMGB1
Year: 2025
Type: article
Language: en
Topic: Advanced Glycation End Products research
Authors and affiliations:
raw_author_name: Huangxi Fu
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Feng Jiang
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Anqi Xu
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Taicheng Zhou
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Ning Liu
raw_affiliation_strings: Emergency Department, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016 Zhejiang, PR China
raw_author_name: Xueqin Chen
raw_affiliation_strings: Thoracic Cancer Department, Hangzhou Cancer Hospital, Hangzhou 310002 Zhejiang, PR China; Department of Medical Oncology, Affiliated Hangzhou First People's Hospital, Xihu University School of Medicine, Hangzhou 310006 Zhejiang, PR China
raw_author_name: Zizheng Gao
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Wentong Wu
raw_affiliation_strings: Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou 310018 Zhejiang, PR China
raw_author_name: Hao Yan
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Xiaochun Yang
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Bo Yang
raw_affiliation_strings: Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou 310018 Zhejiang, PR China; School of Medicine, Hangzhou City University, Hangzhou 310015 Zhejiang, PR China; Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China
raw_author_name: Qiaojun He
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou 310018 Zhejiang, PR China; Department of Cardiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009 Zhejiang, PR China
raw_author_name: Peihua Luo
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou 310018 Zhejiang, PR China; Department of Cardiology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009 Zhejiang, PR China
raw_author_name: Zhifei Xu
raw_affiliation_strings: Center for Drug Safety Evaluation and Research of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, PR China. Electronic address: xzfzjut@zju.edu.cn