Decreased scleral Wnt5ahi fibroblasts exacerbate myopia progression by disrupting extracellular matrix homeostasis in mice
Year: 2025
Type: article
Language: en
Topic: Ophthalmology and Visual Impairment Studies
Authors and affiliations:
raw_author_name: He Zhu
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Wei Chen
raw_affiliation_strings: Key Laboratory of Biomechanics and Mechanobiology (Ministry of Education), Key Laboratory of Innovation and Transformation of Advanced Medical Devices (Ministry of Industry and Information Technology), National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering), School of Engineering Medicine, Beihang University, Beijing, China
raw_author_name: Xuemei Ling
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Shiming Jiao
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Le Yu
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Huihui Liu
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Mengyi Ding
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Fan Zhang
raw_affiliation_strings: Key Laboratory of Biomechanics and Mechanobiology (Ministry of Education), Key Laboratory of Innovation and Transformation of Advanced Medical Devices (Ministry of Industry and Information Technology), National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering), School of Engineering Medicine, Beihang University, Beijing, China
raw_author_name: Yixin Zhou
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Yulu Pan
raw_affiliation_strings: State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Zhonglou Zhou
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Jia Qu
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China
raw_author_name: Fei Zhao
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China. zhaofei@eye.ac.cn
Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China. zhaofuxing12@163.com
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China. zhaofei@eye.ac.cn
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China. zhaofuxing12@163.com
raw_author_name: Fuxin Zhao
raw_affiliation_strings: Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China. zhaofei@eye.ac.cn
Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China. zhaofuxing12@163.com
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China. zhaofei@eye.ac.cn
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China. zhaofuxing12@163.com
raw_author_name: Xiangtian Zhou
raw_affiliation_strings: Department of Ophthalmology, State Key Laboratory of Eye Health, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhouxt@shsmu.edu.cn
Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences (2019RU025), Wenzhou, Zhejiang, China. zhouxt@shsmu.edu.cn
State Key Laboratory of Eye Health, Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Eye Hospital, Wenzhou Medical University, Wenzhou, China. zhouxt@shsmu.edu.cn