Genomic characterization of colorectal tumors: insights into significantly mutated genes, pathways, and survival outcomes
Year: 2025
Type: article
Language: en
Topic: Colorectal Cancer Treatments and Studies
Authors and affiliations:
raw_author_name: Tabitha A. Harrison
raw_affiliation_strings: Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. haratabi@uw.edu
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. haratabi@uw.edu
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA
raw_author_name: Syed H. Zaidi
raw_affiliation_strings: Ontario Institute for Cancer Research, Toronto, ON, Canada
raw_author_name: Hang Yin
raw_affiliation_strings: Institute for Public Health Genetics, School of Public Health, University of Washington, Seattle, WA, USA
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Robert S. Steinfelder
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Conghui Qu
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Elom K. Aglago
raw_affiliation_strings: Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
raw_author_name: Sonja I. Berndt
raw_affiliation_strings: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
raw_author_name: Lisa A. Boardman
raw_affiliation_strings: Comprehensive Cancer Center, Mayo Clinic, Rochester, MN, USA
raw_author_name: Hermann Brenner
raw_affiliation_strings: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany
raw_author_name: Daniel D. Buchanan
raw_affiliation_strings: Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia
Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia
University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia
raw_author_name: Peter T. Campbell
raw_affiliation_strings: Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
raw_author_name: Yin Cao
raw_affiliation_strings: Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St Louis, MO, USA
Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St Louis, MO, USA
raw_author_name: Andrew T. Chan
raw_affiliation_strings: Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Stephen J. Chanock
raw_affiliation_strings: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
raw_author_name: Kimberly F. Doheny
raw_affiliation_strings: Center for Inherited Disease Research (CIDR), Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: David A. Drew
raw_affiliation_strings: Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Jane C. Figueiredo
raw_affiliation_strings: Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
raw_author_name: Amy J. French
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics, Mayo Clinic, Rochester, MN, USA
raw_author_name: Steven Gallinger
raw_affiliation_strings: Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
raw_author_name: Peter Georgeson
raw_affiliation_strings: Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia
University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia
raw_author_name: Marios Giannakis
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA, USA
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Ellen L. Goode
raw_affiliation_strings: Department of Quantitative Health Sciences, Division of Epidemiology, Mayo Clinic, Rochester, MN, USA
raw_author_name: Stephen B. Gruber
raw_affiliation_strings: Department of Medical Oncology and Therapeutics Research and Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, USA
raw_author_name: Andrea Gsur
raw_affiliation_strings: Center for Cancer Research, Medical University of Vienna, Vienna, Austria
raw_author_name: Marc J. Gunter
raw_affiliation_strings: Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK
Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
raw_author_name: Sophia Harlid
raw_affiliation_strings: Department of Diagnostics and Intervention, Oncology Unit, Umeå University, Umeå, Sweden
raw_author_name: Michael Hoffmeister
raw_affiliation_strings: Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
raw_author_name: Wen-Yi Huang
raw_affiliation_strings: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
raw_author_name: Meredith AJ. Hullar
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Jeroen R. Huyghe
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Mark A. Jenkins
raw_affiliation_strings: Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia
raw_author_name: Yi Lin
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Victor Moreno
raw_affiliation_strings: Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain
ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain
Oncology Data Analytics Program (ODAP), Unit of Biomarkers and Suceptibility (UBS), Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain
raw_author_name: Neil Murphy
raw_affiliation_strings: Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
raw_author_name: Polly A. Newcomb
raw_affiliation_strings: Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Christina C. Newton
raw_affiliation_strings: Department of Population Science, American Cancer Society, Atlanta, GA, USA
raw_author_name: Jonathan A. Nowak
raw_affiliation_strings: Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Mireia Obón-Santacana
raw_affiliation_strings: Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain
ONCOBELL Program, Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain
Oncology Data Analytics Program (ODAP), Unit of Biomarkers and Suceptibility (UBS), Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain
raw_author_name: Shuji Ogino
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA, USA
Cancer Immunology Program, Dana-Farber Cancer Institute, Boston, MA, USA
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA
Division of Nutrition, Harvard Medical School, Boston, MA, USA
Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Tameka Shelford
raw_affiliation_strings: Center for Inherited Disease Research (CIDR), Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Mingyang Song
raw_affiliation_strings: Clinical and Translational Epidemiology Unit, Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Departments of Epidemiology and Nutrition, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA
raw_author_name: Claire E. Thomas
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Amanda E. Toland
raw_affiliation_strings: Departments of Cancer Biology and Genetics and Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA
raw_author_name: Tomotaka Ugai
raw_affiliation_strings: Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA
Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Caroline Y. Um
raw_affiliation_strings: Department of Population Science, American Cancer Society, Atlanta, GA, USA
raw_author_name: Bethany Van Guelpen
raw_affiliation_strings: Department of Diagnostics and Intervention, Oncology Unit, Umeå University, Umeå, Sweden
Wallenberg Centre for Molecular Medicine, Umeå University, Umeå, Sweden
raw_author_name: Quang M. Trinh
raw_affiliation_strings: Ontario Institute for Cancer Research, Toronto, ON, Canada
raw_author_name: Wei Sun
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Thomas J. Hudson
raw_affiliation_strings: Ontario Institute for Cancer Research, Toronto, ON, Canada
raw_author_name: Li Hsu
raw_affiliation_strings: Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
raw_author_name: Ulrike Peters
raw_affiliation_strings: Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA. upeters@fredhutch.org
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA. upeters@fredhutch.org
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA
raw_author_name: Amanda I. Phipps
raw_affiliation_strings: Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA
Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA, USA