Design and Structural Optimization of Orally Bioavailable RSK4 Inhibitors for the Treatment of Esophageal Squamous Cell Carcinoma
Year: 2025
Type: article
Language: en
Topic: Melanoma and MAPK Pathways
Authors and affiliations:
raw_author_name: Limin Leng
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Shuai He
raw_affiliation_strings: Baotou Medical College
Department of Pathology, School of Basic Medicine and Forensic Science
Fourth Military Medical University
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China
raw_author_name: Manzhan Zhang
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Yanru Yang
raw_affiliation_strings: Fourth Military Medical University
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China
raw_author_name: Yuanyuan Ge
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Yuan Yuan
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Qiqi Niu
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Xiayu Shi
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Zhuo Chen
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Zhenjiang Zhao
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Huan He
raw_affiliation_strings: East China Normal University
Innovation Center for AI and Drug Discovery, School of Pharmacy
raw_author_name: Honglin Li
raw_affiliation_strings: East China Normal University
East China University of Science and Technology
Innovation Center for AI and Drug Discovery, School of Pharmacy
School of Pharmacy
School of Pharmacy, East China University of Science and Technology, Shanghai 200030, China
raw_author_name: Yufang Xu
raw_affiliation_strings: East China University of Science and Technology
School of Pharmacy
raw_author_name: Zhe Wang
raw_affiliation_strings: Fourth Military Medical University
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine
State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancer, Xijing Hospital and School of Basic Medicine, Fourth Military Medical University, Xi'an 710032, China
raw_author_name: Shiliang Li
raw_affiliation_strings: East China Normal University
East China University of Science and Technology
Innovation Center for AI and Drug Discovery, School of Pharmacy
School of Pharmacy
School of Pharmacy, East China University of Science and Technology, Shanghai 200030, China