Genetic activation of ERK2 recapitulates core neurodevelopmental features of Rasopathy syndromes in mice
Year: 2025
Type: article
Language: en
Topic: Melanoma and MAPK Pathways
Authors and affiliations:
raw_author_name: Kassidy E. Grover
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Zoe R. Cappel
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Avery Volz
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Evelin M. Cotella
raw_affiliation_strings: Department of Functional and Systems Neuroscience, Instituto Mercedes y Martin Ferreyra INIMEC-CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina
Universidad Nacional de Córdoba
raw_author_name: Kelly Smallwood
raw_affiliation_strings: The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Christine A. Berryhill
raw_affiliation_strings: Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States
Indiana University School of Medicine
raw_author_name: Kimaya R. Raje
raw_affiliation_strings: Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Austen A. Fisher
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Mary Claire T. Casper
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Diana Nardini
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Tilat A. Rizvi
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Rosa M. Salazar
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Ashley Wooten
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Michael T. Williams
raw_affiliation_strings: Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Charles V. Vorhees
raw_affiliation_strings: Department of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Lindsey E. Romick
raw_affiliation_strings: Division of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Kenneth D. Greis
raw_affiliation_strings: Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
University of Cincinnati College of Medicine
raw_author_name: Yueh-Chiang Hu
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Linde A. Miles
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Steven P. Angus
raw_affiliation_strings: Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, 46202, United States
Indiana University School of Medicine
raw_author_name: Nancy Ratner
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Carlos E. Prada
raw_affiliation_strings: Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, United States
Edwards Family Division of Genetics and Rare Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 60611, United States
Ann & Robert H. Lurie Children's Hospital of Chicago
raw_author_name: K. Nicole Weaver
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: Ronald R. Waclaw
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center
raw_author_name: J. Elliott Robinson
raw_affiliation_strings: Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Division of Experimental Hematology and Cancer Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, United States
University of Cincinnati Cancer Center, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, United States
Cincinnati Children's Hospital Medical Center