A single-nucleus transcriptomic analysis reveals hippocampal neuronal alterations linked to anxiety- and depression-like behaviors in IBD model mice
Year: 2025
Type: article
Language: en
Topic: Single-cell and spatial transcriptomics
Authors and affiliations:
raw_author_name: Kangcheng Luo
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: luokangcheng@whu.edu.cn
raw_author_name: Mengting Zhang
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: zhang0790@whu.edu.cn
raw_author_name: Qianwen Tu
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: tuqianwen@whu.edu.cn
raw_author_name: Zhao Ding
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: dingzhao@whu.edu.cn
raw_author_name: Songlin Wan
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: songlinwan@whu.edu.cn
raw_author_name: Jian Li
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: 2022283030091@whu.edu.cn
raw_author_name: Youheng Wang
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: 785113824@qq.com
raw_author_name: Tianran Chen
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: Chentianr1996@163.com
raw_author_name: Daojiang Li
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: daojiangli@whu.edu.cn
raw_author_name: Qun Qian
raw_affiliation_strings: Department of Colorectal and Anal Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Quality Control Center of Colorectal and Anal Surgery, Health Commission of Hubei Province, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China; Wuhan Clinical Research Center for Constipation and Pelvic Floor Disorders, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: qunqian2007@163.com
raw_author_name: Lu Xia
raw_affiliation_strings: Department of Rehabilitation Medicine, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, Hubei province, 430071, China. Electronic address: xialu@whu.edu.cn