Genetic liability to psoriasis predicts severe disease outcomes
Year: 2025
Type: article
Language: en
Topic: Psoriasis: Treatment and Pathogenesis
Authors and affiliations:
raw_author_name: Jake R. Saklatvala
raw_affiliation_strings: Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9RT, UK
raw_author_name: Samuel Lessard
raw_affiliation_strings: Target, Disease & Systems Biology, Sanofi Research, Cambridge, MA, USA
raw_author_name: Maris Teder-Laving
raw_affiliation_strings: Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
raw_author_name: Laurent F. Thomas
raw_affiliation_strings: BioCore - Bioinformatics Core Facility, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
Department of Clinical and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
raw_author_name: Ravi Ramessur
raw_affiliation_strings: St John's Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK
raw_author_name: Jonas Zierer
raw_affiliation_strings: Immunology Disease Area, Biomedical Research, Novartis Pharma AG, Basel, Switzerland
raw_author_name: Bjørn Olav Åsvold
raw_affiliation_strings: Department of Endocrinology, Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
raw_author_name: Anne Barton
raw_affiliation_strings: Centre for Genetics and Genomics Versus Arthritis, The University of Manchester, Manchester, UK
National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Centre, The University of Manchester, Manchester, UK
The Kellgren Centre for Rheumatology, Manchester University NHS Foundation Trust, Manchester, UK
raw_author_name: David Baudry
raw_affiliation_strings: St John's Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK
raw_author_name: John Bowes
raw_affiliation_strings: Centre for Genetics and Genomics Versus Arthritis, The University of Manchester, Manchester, UK
National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Centre, The University of Manchester, Manchester, UK
raw_author_name: Ben Brumpton
raw_affiliation_strings: Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7030, Trondheim, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway
raw_author_name: Sandro Bruno
raw_affiliation_strings: Immunology Disease Area, Biomedical Research, Novartis Pharma AG, Basel, Switzerland
raw_author_name: Vinod Chandran
raw_affiliation_strings: Schroeder Arthritis Institute, Krembil Research Institute, and Toronto Western Hospital, University Health Network and Departments of Medicine/Rheumatology, Institute of Medical Science, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
raw_author_name: Clément Chatelain
raw_affiliation_strings: Target, Disease & Systems Biology, Sanofi Research, Cambridge, MA, USA
raw_author_name: Emanuele de Rinaldis
raw_affiliation_strings: Target, Disease & Systems Biology, Sanofi Research, Cambridge, MA, USA
raw_author_name: James T. Elder
raw_affiliation_strings: Ann Arbor Veterans Affairs Hospital, Ann Arbor, MI, USA
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: David Ellinghaus
raw_affiliation_strings: Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
raw_author_name: John Foerster
raw_affiliation_strings: College of Medicine, Dentistry, and Nursing, University of Dundee, Dundee, UK
raw_author_name: Andre Franke
raw_affiliation_strings: Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
raw_author_name: Dafna D. Gladman
raw_affiliation_strings: Schroeder Arthritis Institute, Krembil Research Institute, and Toronto Western Hospital, University Health Network and Departments of Medicine/Rheumatology, Institute of Medical Science, and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
raw_author_name: Wayne Gulliver
raw_affiliation_strings: Department of Dermatology, Discipline of Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada
Newlab Clinical Research Inc, St. John's, NL, Canada
raw_author_name: Ulrike Hüffmeier
raw_affiliation_strings: Institute of Human Genetics, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany
raw_author_name: Laura Huilaja
raw_affiliation_strings: Department of Dermatology and Medical Research Center, Oulu University Hospital and Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland
raw_author_name: Kristian Hveem
raw_affiliation_strings: Department of Innovation and Research, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, Norway
raw_author_name: Shameer Khader
raw_affiliation_strings: Target, Disease & Systems Biology, Sanofi Research, Cambridge, MA, USA
raw_author_name: Külli Kingo
raw_affiliation_strings: Faculty of Medicine, Institute of Clinical Medicine, University of Tartu, Tartu University Hospital, Tartu, Estonia
raw_author_name: Katherine Klinger
raw_affiliation_strings: Genetics Research, Sanofi, Cambridge, MA, USA
raw_author_name: Frank Kolbinger
raw_affiliation_strings: Immunology Disease Area, Biomedical Research, Novartis Pharma AG, Basel, Switzerland
raw_author_name: Sulev Kõks
raw_affiliation_strings: Centre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University, Perth, WA, 6150, Australia
Perron Institute for Neurological and Translational Science, Nedlands, WA, 6009, Australia
raw_author_name: Wilson Liao
raw_affiliation_strings: Deparment of Dermatology, University of California San Francisco, San Francisco, CA, USA
raw_author_name: Rajan P. Nair
raw_affiliation_strings: Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Joanne Nititham
raw_affiliation_strings: Deparment of Dermatology, University of California San Francisco, San Francisco, CA, USA
raw_author_name: Proton Rahman
raw_affiliation_strings: Memorial University of Newfoundland, St. John's, NL, Canada
raw_author_name: André Reis
raw_affiliation_strings: Institute of Human Genetics, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany
raw_author_name: Manpreet K. Sagoo
raw_affiliation_strings: St John's Institute of Dermatology, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, UK
raw_author_name: Philip E. Stuart
raw_affiliation_strings: Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Kaisa Tasanen
raw_affiliation_strings: Department of Dermatology and Medical Research Center, Oulu University Hospital and Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland
raw_author_name: Tanel Traks
raw_affiliation_strings: Department of Dermatology and Venereology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia
raw_author_name: Lam C. Tsoi
raw_affiliation_strings: Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Steffen Uebe
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raw_author_name: Katie Watts
raw_affiliation_strings: MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, UK
raw_author_name: BSTOP study group
raw_author_name: Nadia Aldoori
raw_author_name: Mahmud Ali
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raw_author_name: Fiona Antony
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raw_author_name: Periasamy Balasubramaniam
raw_author_name: Kay Baxter
raw_author_name: Anthony Bewley
raw_author_name: Alexandra Bonsall
raw_affiliation_strings: Department of Dermatology, NHS Lothian, Edinburgh, UK
Centre for Genomic & Experimental Medicine, Institute of Genetics and Cancer, The University of Edinburgh, Edinburgh, UK
raw_author_name: Victoria Brown
raw_author_name: Katya Burova
raw_author_name: Aamir Butt
raw_author_name: Mel Caswell
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raw_author_name: Sharmela Darne
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raw_author_name: Trupti Desai
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raw_affiliation_strings: Department of Medical & Molecular Genetics, School of Basic & Medical Biosciences, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9RT, UK
raw_author_name: Michael Duckworth
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raw_author_name: Caoimhe Fahy
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