MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors
Year: 2025
Type: article
Language: en
Topic: DNA Repair Mechanisms
Authors and affiliations:
raw_author_name: Hülya Dogan
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Martin Liptay
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Joana S. Barbosa
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Ewa Gogola
raw_affiliation_strings: Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam,  1066CX, The Netherlands
raw_author_name: Alexandra A. Duarte
raw_affiliation_strings: Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam,  1066CX, The Netherlands
raw_author_name: Jonas A. Schmid
raw_affiliation_strings: Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland
raw_author_name: Ismar Klebic
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Merve Mutlu
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Myriam Siffert
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Paola Francica
raw_affiliation_strings: Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Israel Salguero
raw_affiliation_strings: Spanish National Cancer Research Center, Madrid, 28029, Spain
Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Rd, Cambridge, CB2 1QN, UK
Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Tennis Court Rd, Cambridge,  CB2 1QN, UK
raw_author_name: Marieke van de Ven
raw_affiliation_strings: Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
raw_author_name: Renske de Korte-Grimmerink
raw_affiliation_strings: Mouse Clinic for Cancer and Aging Research (MCCA), Preclinical Intervention Unit, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
raw_author_name: Stephen P. Jackson
raw_affiliation_strings: Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK
raw_author_name: Jos Jonkers
raw_affiliation_strings: Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
Oncode Institute, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands
Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam,  1066CX, The Netherlands
raw_author_name: Massimo Lopes
raw_affiliation_strings: Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland
raw_author_name: Diego Dibitetto
raw_affiliation_strings: Department of Experimental Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri, 2, Milan, 20156, Italy. diego.dibitetto@marionegri.it
Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland. diego.dibitetto@marionegri.it
Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland
raw_author_name: Sven Rottenberg
raw_affiliation_strings: Bern Center for Precision Medicine, Department for BioMedical Research, University of Bern, Bern, 3012, Switzerland. sven.rottenberg@unibe.ch
Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, 1066CX, The Netherlands. sven.rottenberg@unibe.ch
Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, Bern, 3012, Switzerland. sven.rottenberg@unibe.ch
Bern Center for Precision Medicine, Department for BioMedical Research, University of Bern, Bern, 3012, Switzerland