TBK1 Induces the Formation of Optineurin Filaments That Condensate with Polyubiquitin and LC3 for Cargo Sequestration
Year: 2025
Type: article
Language: en
Topic: Autophagy in Disease and Therapy
Authors and affiliations:
raw_author_name: Maria G. Herrera
raw_affiliation_strings: Department Molecular Cell Biology Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Faculty of Exact and Natural Sciences Institute of Biosciences Biotechnology and Translational Biology (iB3) University of Buenos Aires  Intendente Güiraldes 2160, Ciudad Universitaria Buenos Aires C1428EGA Argentina
Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany
raw_author_name: Lena Kühn
raw_affiliation_strings: Department Molecular Cell Biology Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany
raw_author_name: Lisa Jungbluth
raw_affiliation_strings: Ernst‐Ruska Centre for Microscopy and Spectroscopy with Electrons  ER‐C‐3/Structural Biology, Forschungszentrum Jülich 52425 Jülich Germany
raw_author_name: Verian Bader
raw_affiliation_strings: Department Biochemistry of Neurodegenerative Diseases Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Department Molecular Cell Biology Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Department Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany
raw_author_name: Laura J. Krause
raw_affiliation_strings: Department Molecular Cell Biology Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Department Molecular Cell Biology, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, 44801 Bochum, Germany
raw_author_name: David Kartte
raw_affiliation_strings: Ernst‐Ruska Centre for Microscopy and Spectroscopy with Electrons  ER‐C‐3/Structural Biology, Forschungszentrum Jülich 52425 Jülich Germany
raw_author_name: Elias Adriaenssens
raw_affiliation_strings: Max Perutz Labs, Department of Biochemistry and Cell Biology University of Vienna  Vienna 1030 Austria
Max Perutz Labs, Vienna Biocenter Campus (VBC)  Vienna 1030 Austria
Max Perutz Labs, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, 1030 Austria
Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030 Austria
raw_author_name: Sascha Martens
raw_affiliation_strings: Max Perutz Labs, Department of Biochemistry and Cell Biology University of Vienna  Vienna 1030 Austria
Max Perutz Labs, Vienna Biocenter Campus (VBC)  Vienna 1030 Austria
Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030 Austria
Max Perutz Labs, Department of Biochemistry and Cell Biology, University of Vienna, Vienna, 1030 Austria
raw_author_name: Jörg Tatzelt
raw_affiliation_strings: Cluster of Excellence RESOLV Ruhr University Bochum  44801 Bochum Germany
Department Biochemistry of Neurodegenerative Diseases Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Cluster of Excellence RESOLV, Ruhr University Bochum, 44801 Bochum, Germany
raw_author_name: Carsten Sachse
raw_affiliation_strings: Department of Biology Heinrich Heine University  Universitätsstr. 1 40225 Düsseldorf Germany
Ernst‐Ruska Centre for Microscopy and Spectroscopy with Electrons  ER‐C‐3/Structural Biology, Forschungszentrum Jülich 52425 Jülich Germany
raw_author_name: Konstanze F. Winklhofer
raw_affiliation_strings: Cluster of Excellence RESOLV Ruhr University Bochum  44801 Bochum Germany
Department Molecular Cell Biology Institute of Biochemistry and Pathobiochemistry Ruhr University Bochum  44801 Bochum Germany
Cluster of Excellence RESOLV, Ruhr University Bochum, 44801 Bochum, Germany