Dual-target CAR-T therapy for ovarian cancer: synergistic targeting of MSLN and B7H3 enhances anti-tumor efficacy and overcomes antigen heterogeneity
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Feng Ji
raw_affiliation_strings: Department of Clinical Science and Research, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Kai Yan
raw_affiliation_strings: State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Bo Ding
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Yuxin Zhu
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Mengchen Rao
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Kexing Gao
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Hao Lin
raw_affiliation_strings: Department of Clinical Science and Research, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Yiyang Shan
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Sicong Liu
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Zhongdang Xiao
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China. zdxiao@seu.edu.cn
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, China. zdxiao@seu.edu.cn
Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
raw_author_name: Yang Shen
raw_affiliation_strings: Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China. shenyang@seu.edu.cn
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China. shenyang@seu.edu.cn
Department of Obstetrics and Gynecology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China
Nanjing Key Laboratory of Intelligent Obstetrics and Gynecology Medicine, Southeast University, Nanjing, Jiangsu, China