Glycochenodeoxycholic acid promotes hepatocarcinogenesis by inducing hepatic progenitor cell differentiation into cancer-associated fibroblasts via sphingosine-1-phosphate receptor 2 signalling
Year: 2025
Type: article
Language: en
Topic: Liver physiology and pathology
Authors and affiliations:
raw_author_name: Lu Gao
raw_affiliation_strings: Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Gang Lv
raw_affiliation_strings: Senior Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, China
raw_author_name: Ying Huang
raw_affiliation_strings: Institute of Advanced Clinical Medicine, Peking University, Beijing, China
State Key Laboratory of Female Fertility Promotion, Department of Endocrinology and Metabolism, Third Hospital, Peking University, Beijing, China
raw_author_name: Mengmeng Xue
raw_affiliation_strings: School of Pharmacy, Anhui Medical University, Hefei, China
raw_author_name: Zhipeng Zhang
raw_affiliation_strings: Cancer Center, Beijing Key Laboratory for Interdisciplinary Research in Gastrointestinal Oncology, Peking University Third Hospital, Peking University, Beijing, China
Department of General Surgery, Peking University Third Hospital, Peking University, Beijing, China
raw_author_name: Jing Weng
raw_affiliation_strings: Department of General Surgery, Peking University Third Hospital, Peking University, Beijing, China
raw_author_name: Haoran Bai
raw_affiliation_strings: Department of Oncology, Longhua Hospital Affiliated to , Shanghai University of Traditional Chinese Medicine, Shanghai, China
raw_author_name: Min Tao
raw_affiliation_strings: School of Pharmacy, Anhui Medical University, Hefei, China
raw_author_name: Xi Luo
raw_affiliation_strings: Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
raw_author_name: Yuhua Gao
raw_affiliation_strings: Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
raw_author_name: Shiyao Feng
raw_affiliation_strings: Department of Urology, Chao hu Hospital of Anhui Medical University, Anhui, China
raw_author_name: Xiaojuan Hou
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Chen Zong
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Xue Yang
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Qiudong Zhao
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Jinghua Jiang
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China
raw_author_name: Xinyu Zhu
raw_affiliation_strings: Changhai Clinical Research Unit, Changhai Hospital of Naval Medical University, Shanghai, China
raw_author_name: Zhipeng Han
raw_affiliation_strings: Department of Oncology, Longhua Hospital Affiliated to , Shanghai University of Traditional Chinese Medicine, Shanghai, China
raw_author_name: Changtao Jiang
raw_affiliation_strings: Department of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing, China
State Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
raw_author_name: Dongyu Zhao
raw_affiliation_strings: Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing, China. zhaodongyu@bjmu.edu.cn
raw_author_name: Lixin Wei
raw_affiliation_strings: Department of Tumor Immune and Metabolism, National Center for Liver Cancer, Naval Medical University, Shanghai, China. lixinwei@smmu.edu.cn
raw_author_name: Lulu Sun
raw_affiliation_strings: Institute of Advanced Clinical Medicine, Peking University, Beijing, China. lulusun@bjmu.edu.cn
State Key Laboratory of Female Fertility Promotion, Department of Endocrinology and Metabolism, Third Hospital, Peking University, Beijing, China. lulusun@bjmu.edu.cn