Reversing Autophagy Inhibition Ameliorates Neurodegeneration in Hereditary Spastic Paraplegia Caused by a Degradation‐Resistant <scp> <i>SPAST</i> </scp> Mutation
Year: 2025
Type: article
Language: en
Topic: Hereditary Neurological Disorders
Authors and affiliations:
raw_author_name: Dingyi Zhang
raw_affiliation_strings: Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University  Chongqing China
Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University Chongqing China
These authors contributed equally to this work
raw_author_name: Yang Hu
raw_affiliation_strings: Department of Neurology The Second Affiliated Hospital of Chongqing Medical University  Chongqing China
Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
These authors contributed equally to this work
raw_author_name: Jianhe Guo
raw_affiliation_strings: Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University  Chongqing China
Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University Chongqing China
These authors contributed equally to this work
raw_author_name: Dongmei Wu
raw_affiliation_strings: Department of Neurology The Second Affiliated Hospital of Chongqing Medical University  Chongqing China
These authors contributed equally to this work
Department of Neurology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
raw_author_name: Yifan Zhang
raw_affiliation_strings: Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University  Chongqing China
Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education)
Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University Chongqing China
raw_author_name: Lingzi Yang
raw_affiliation_strings: Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University  Chongqing China
Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University Chongqing China
Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education)
raw_author_name: Yuxi Wang
raw_affiliation_strings: Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders  Chongqing China
Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China
raw_author_name: Nong Xiao
raw_affiliation_strings: Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders  Chongqing China
Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China
raw_author_name: Jinhua Fan
raw_affiliation_strings: Central Laboratory Chongqing University Fuling Hospital, Chongqing University  Chongqing China
Central Laboratory, Chongqing University Fuling Hospital, Chongqing University, Chongqing, China
raw_author_name: Yanling Dong
raw_affiliation_strings: Department of Obstetrics The First Affiliated Hospital of Chongqing Medical University  Chongqing China
Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
raw_author_name: Min Zhong
raw_affiliation_strings: Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders  Chongqing China
Department of Rehabilitation, Jiangxi Children's Medical Center, Jiangxi Provincial Key Laboratory of Birth Defect for Prevention and Control  Jiangxi China
Department of Rehabilitation, Jiangxi Children's Medical Center, Jiangxi Provincial Key Laboratory of Birth Defect for Prevention and Control, Jiangxi, China
Department of Rehabilitation, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, Chongqing, China
raw_author_name: Tongfei Liu
raw_affiliation_strings: Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University  Chongqing China
Department of Neurobiology, School of Basic Medical Sciences
Department of Neurobiology, School of Basic Medical Sciences; Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education); Department of Neurology The First Affiliated Hospital of Chongqing Medical University, Chongqing Medical University Chongqing China
Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education)