Single cell transcriptomics of human weight loss links adipocyte NPY1R to control of lipolysis
Year: 2025
Type: article
Language: en
Topic: Adipokines, Inflammation, and Metabolic Diseases
Authors and affiliations:
raw_author_name: Julius E.R. Grothen
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
raw_author_name: Jaime M. Martinez
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Nikos Sidiropoulos
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Lucas Massier
raw_affiliation_strings: Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge, Sweden; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany
Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany
raw_author_name: Danae Zareifi
raw_affiliation_strings: Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge, Sweden
Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge
raw_author_name: Jiawei Zhong
raw_affiliation_strings: Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge, Sweden
Department of Medicine (H7), Karolinska Institutet, C2-94, Karolinska University Hospital, Huddinge
raw_author_name: Ida Davidsen
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Jette W. Platou
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Jette Mandelbaum
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Pia Rothe
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Henning Hvid
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Mads Grønborg
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Christian Toft Madsen
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark
raw_author_name: Jens M. Bruun
raw_affiliation_strings: Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark; Danish National Center for Obesity, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
raw_author_name: Mikael Rydén
raw_affiliation_strings: Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark; Steno Diabetes Center, Copenhagen, Denmark
raw_author_name: Niklas Mejhert
raw_affiliation_strings: Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark; Steno Diabetes Center, Copenhagen, Denmark
raw_author_name: Jørn W. Helge
raw_affiliation_strings: Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
raw_author_name: Zachary Gerhart-Hines
raw_affiliation_strings: Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark. Electronic address: zpg@sund.ku.dk
raw_author_name: Thomas Å. Pedersen
raw_affiliation_strings: Novo Nordisk A/S, Research & Development, Måløv, Denmark. Electronic address: tqpe@novonordisk.com