Synthetic lethality from the combination of a histone methyltransferase SUV39H2 inhibitor and a poly (ADP-ribose) polymerase inhibitor for uterine leiomyosarcoma
Year: 2025
Type: article
Language: en
Topic: PARP inhibition in cancer therapy
Authors and affiliations:
raw_author_name: Yusuke Toyohara
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
raw_author_name: Kenbun Sone
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ksone5274@gmail.com
Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Kohei Kumegawa
raw_affiliation_strings: Cancer Cell Diversity Project, NEXT-Ganken Program, Japanese Foundation for Cancer Research, Tokyo, Japan
raw_author_name: Yoko Yamamoto
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Ryuta Hachijo
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
raw_author_name: Asako Kukita
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Ayumi Taguchi
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Masako Ikemura
raw_affiliation_strings: Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Yuichiro Miyamoto
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Michihiro Tanikawa
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Takayuki Iriyama
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Mayuyo Mori
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Ryuji Hamamoto
raw_affiliation_strings: Cancer Translational Research Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
Division of Medical AI Research and Development, National Cancer Center Research Institute, Tokyo, Japan
raw_author_name: Tetsuo Ushiku
raw_affiliation_strings: Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Katsuhiko Oda
raw_affiliation_strings: Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Yasushi Hirota
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Reo Maruyama
raw_affiliation_strings: Cancer Cell Diversity Project, NEXT-Ganken Program, Japanese Foundation for Cancer Research, Tokyo, Japan
Division of Cancer Epigenomics, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan
raw_author_name: Yutaka Osuga
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan