Improving Activity and C <sub>β</sub> -Stereoselectivity of <scp>l</scp> -Threonine Transaldolase via Structure-Guided Protein Engineering and a Visual High-Throughput Screening Method
Year: 2025
Type: article
Language: en
Topic: Biomedical Research and Pathophysiology
Authors and affiliations:
raw_author_name: Zonghao Li
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Shanshan Yu
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Jinhui Feng
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Xiang Sheng
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Yucheng Gu
raw_affiliation_strings: Jealott’s Hill International Research Centre
Syngenta Ltd
Syngenta Ltd, Jealott's Hill International Research Centre, Bracknell Rg42 6ey, U.K
raw_author_name: Peiyuan Yao
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Qiaqing Wu
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China
raw_author_name: Dunming Zhu
raw_affiliation_strings: National Center of Technology Innovation for Synthetic Biology, National Engineering Research Center of Industrial Enzymes and Tianjin Engineering Research Center of Biocatalytic Technology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
State Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, 32 Xi Qi Dao, Tianjin Airport Economic Area, Tianjin 300308, China
University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Beijing 100049, China