Aptamer-Mediated Covalent Dual Lysosome-Targeting Chimeras Enhance Targeted Degradation of Cell Surface Proteins
Year: 2025
Type: article
Language: en
Topic: Click Chemistry and Applications
Authors and affiliations:
raw_author_name: Tao Peng
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
School of Chemistry and Materials
University of Science and Technology of China
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
School of Chemistry and Materials, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China
raw_author_name: Min Su
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
raw_author_name: Zuying Zhang
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
School of Chemistry and Materials
University of Science and Technology of China
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
School of Chemistry and Materials, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China
raw_author_name: Ya Wang
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
raw_author_name: Yingdi Zhu
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
raw_author_name: Juan Li
raw_affiliation_strings: Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences
School of Chemistry and Materials
University of Science and Technology of China
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application
Zhejiang Cancer Hospital, Zhejiang Key Laboratory of Functional Nucleic Acids for Basic and Clinical Application, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, P. R. China
School of Chemistry and Materials, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China