A novel fully human anti-ROR1 antibody PBA-0405 optimized for ADCC, induces potent anti-tumor activity against both solid and hematological malignancies
Year: 2025
Type: article
Language: en
Topic: Monoclonal and Polyclonal Antibodies Research
Authors and affiliations:
raw_author_name: Niina Veitonmäki
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Anna Kostyn
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Sonia Kołt
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Aleksandra Ziemblicka
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Beata Romanowska
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Sabina Oleksy
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Ewelina Krzywińska
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Kamilla Sołtys
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Łukasz Świderski
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Piotr Naporowski
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Piotr Mamczur
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Monika Świtoń
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Marek Orłowski
raw_affiliation_strings: Department of Biochemistry, Molecular Biology and Biotechnology, Faculty of Chemistry, Wroclaw University of Science and Technology, Wroclaw, Poland
Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Ying Zhang
raw_affiliation_strings: GemPharmatech Co. Ltd., Nanjing, China
raw_author_name: Jianming Xu
raw_affiliation_strings: GemPharmatech Co. Ltd., Nanjing, China
raw_author_name: Anna Andrzejczak
raw_affiliation_strings: Laboratory of Genetics and Epigenetics of Human Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
raw_author_name: Aleksandra Bielawska-Pohl
raw_affiliation_strings: Laboratory of Biology of Stem and Neoplastic Cells, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
raw_author_name: Lidia Karabon
raw_affiliation_strings: Laboratory of Genetics and Epigenetics of Human Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland
raw_author_name: Dariusz Wołowiec
raw_affiliation_strings: Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wrocław, Poland
raw_author_name: Wondossen Sime
raw_affiliation_strings: IVRS AB, Lund, Sweden
raw_author_name: Ramin Massoumi
raw_affiliation_strings: IVRS AB, Lund, Sweden
raw_author_name: Sameer Deshmukh
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Jakub Kołodziejski
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Tomasz Klaus
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland
raw_author_name: Pieter Spee
raw_affiliation_strings: Pure Biologics S. A., Wroclaw, Poland