Automated GMP-compatible production of universal CAR Tregs for organ-targeted tolerance induction
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Kavitha Lakshmi
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Alexandra von Jutrzenka-Trzebiatowski
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
raw_author_name: Liliana Loureiro
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
raw_author_name: Karla Elizabeth González Soto
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
raw_author_name: Katja Peter
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
raw_author_name: José Manuel Marín Morales
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Samikshya Santosh Nirmala
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Nicole Berndt
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
raw_author_name: Claudia Arndt
raw_affiliation_strings: Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Yueyuan Hu
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
DKMS Stem Cell Bank, Deutsche Knochenmarkspenderdatei (DKMS), Dresden, Germany
raw_author_name: Jing-Wun Li
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Claudia Peitzsch
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Anna Taubenberger
raw_affiliation_strings: Biotechnology Center, Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Rebekka Wehner
raw_affiliation_strings: Faculty of Medicine Carl Gustav Carus, Institute of Immunology, TUD Dresden University of Technology, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany
National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Heidelberg, Germany
raw_author_name: Marc Schmitz
raw_affiliation_strings: Faculty of Medicine Carl Gustav Carus, Institute of Immunology, TUD Dresden University of Technology, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany
National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Heidelberg, Germany
raw_author_name: Kristina Hölig
raw_affiliation_strings: Department of Transfusion Medicine, Medical Clinic I (MK1), University Hospital Carl Gustav Carus, Dresden, Germany
Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East, Dresden, Germany
raw_author_name: Hinrich Abken
raw_affiliation_strings: Division for Genetic Immunotherapy, Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany
raw_author_name: Ezio Bonifacio
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
raw_author_name: Martin Bornhäuser
raw_affiliation_strings: Department of Hematology, Cell Therapy and Medical Oncology at Medical Clinic I (MK1), University Hospital Carl Gustav Carus, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany
National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Heidelberg, Germany
raw_author_name: Michael Bachmann
raw_affiliation_strings: German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Heidelberg, Germany
raw_author_name: Anja Feldmann
raw_affiliation_strings: German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany
National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a Partnership Between DKFZ, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology and Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Heidelberg, Germany
raw_author_name: Anke Fuchs
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany. Anke.Fuchs1@tu-dresden.de
German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany. Anke.Fuchs1@tu-dresden.de
Mildred Scheel Early Career Center, Faculty of Medicine Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany. Anke.Fuchs1@tu-dresden.de
Center for Regenerative Therapies Dresden (CRTD), Center for Molecular and Cellular Bioengineering (CMCB), TUD Dresden University of Technology, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany