Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts
Year: 2025
Type: article
Language: en
Topic: Glioma Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Rachael A Vaubel
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Laboratory Medicine and Pathology, , Rochester, MN
raw_author_name: Wenjuan Zhang
raw_affiliation_strings: Department of Pharmaceutics, College of Pharmacy, University of Minnesota , Minneapolis, MN,
University of Minnesota Department of Pharmaceutics, College of Pharmacy, , Minneapolis, MN
raw_author_name: Nishika Karbhari
raw_affiliation_strings: Department of Neuro-Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Neuro-Oncology, , Rochester, MN
raw_author_name: Ju-Hee Oh
raw_affiliation_strings: Department of Pharmaceutics, College of Pharmacy, University of Minnesota , Minneapolis, MN,
University of Minnesota Department of Pharmaceutics, College of Pharmacy, , Minneapolis, MN
raw_author_name: Katie L Waller
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Laboratory Medicine and Pathology, , Rochester, MN
raw_author_name: Ann Mladek
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Sonia Jain
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Danielle M Burgenske
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Paul A Decker
raw_affiliation_strings: Department of Quantitative Health Sciences, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Quantitative Health Sciences, , Rochester, MN
raw_author_name: Matt L Kosel
raw_affiliation_strings: Department of Quantitative Health Sciences, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Quantitative Health Sciences, , Rochester, MN
raw_author_name: Zeng Hu
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Lauren L Ott
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Brett L Carlson
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Katrina K Bakken
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN
raw_author_name: Tugce Pasa
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Laboratory Medicine and Pathology, , Rochester, MN
raw_author_name: Nicole R Sarkaria
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Laboratory Medicine and Pathology, , Rochester, MN
raw_author_name: Surabhi Talele
raw_affiliation_strings: Department of Pharmaceutics, College of Pharmacy, University of Minnesota , Minneapolis, MN,
University of Minnesota Department of Pharmaceutics, College of Pharmacy, , Minneapolis, MN
raw_author_name: Jeanette E Eckel-Passow
raw_affiliation_strings: Department of Quantitative Health Sciences, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Quantitative Health Sciences, , Rochester, MN
raw_author_name: Patrizia Sini
raw_affiliation_strings: Department of Pharmacology and Translational Research, Boehringer Ingelheim , Vienna,
Boehringer Ingelheim, Vienna, Austria
raw_author_name: William F Elmquist
raw_affiliation_strings: Department of Pharmaceutics, College of Pharmacy, University of Minnesota , Minneapolis, MN,
University of Minnesota Department of Pharmaceutics, College of Pharmacy, , Minneapolis, MN
raw_author_name: Jann N Sarkaria
raw_affiliation_strings: Department of Radiation Oncology, Mayo Clinic , Rochester, MN,
Mayo Clinic Department of Radiation Oncology, , Rochester, MN