Concurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancer
Year: 2025
Type: article
Language: en
Topic: Lung Cancer Treatments and Mutations
Authors and affiliations:
raw_author_name: Meiting Yue
raw_affiliation_strings: Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Zhen Qin
raw_affiliation_strings: Institute of Pathology & Southwest Cancer Center, the First Affiliated Hospital (Southwest Hospital) and School of Basic Medical Sciences, Army Medical University (Third Military Medical University), and the Key Laboratory of Tumor Immunopathology, the Ministry of Education (Third Military Medical University), Chongqing, China
raw_author_name: Shijie Tang
raw_affiliation_strings: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Xinlei Cai
raw_affiliation_strings: Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China
raw_author_name: Yikai Zhao
raw_affiliation_strings: Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China
raw_author_name: Chen Yang
raw_affiliation_strings: Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China
raw_author_name: Liang Chen
raw_affiliation_strings: Institute of Life and Health Engineering, Jinan University, Guangzhou, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. lnchen@sjtu.edu.cn
School of Life Science and Technology, Shanghai Tech University, Shanghai, China. lnchen@sjtu.edu.cn
School of Mathematical Sciences and School of Artificial Intelligence, Shanghai Jiao Tong University, Shanghai, China. lnchen@sjtu.edu.cn
raw_author_name: Luonan Chen
raw_affiliation_strings: Institute of Life and Health Engineering, Jinan University, Guangzhou, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. lnchen@sjtu.edu.cn
School of Life Science and Technology, Shanghai Tech University, Shanghai, China. lnchen@sjtu.edu.cn
School of Mathematical Sciences and School of Artificial Intelligence, Shanghai Jiao Tong University, Shanghai, China. lnchen@sjtu.edu.cn
School of Mathematical Sciences and School of Artificial Intelligence, Shanghai Jiao Tong University, Shanghai, China
raw_author_name: Hongbin Ji
raw_affiliation_strings: Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China. hbji@sibcb.ac.cn
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China. hbji@sibcb.ac.cn
School of Life Science and Technology, Shanghai Tech University, Shanghai, China. hbji@sibcb.ac.cn
University of Chinese Academy of Sciences, Beijing, China. hbji@sibcb.ac.cn
Key Laboratory of Multi-Cell Systems, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China
Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China
School of Life Science and Technology, Shanghai Tech University, Shanghai, China