NKTR-255, a polymer-conjugated IL-15, synergizes with CAR-T cell therapy to activate endogenous anti-tumor immunity and improve tumor control
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: W. Sam Nutt
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Molecular and Cell Biology Graduate Program, University of Washington; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Mitchell G. Kluesner
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Medical Scientist Training Program, University of Washington School of Medicine; Seattle, WA, USA
Molecular and Cell Biology Graduate Program, University of Washington; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Emma Bingham
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Ekram Gad
raw_affiliation_strings: Comparative Medicine (TRMS), Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Dani Miller
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Victor Zepeda
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Andrew J. Snyder
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Medical Scientist Training Program, University of Washington School of Medicine; Seattle, WA, USA
Molecular and Cell Biology Graduate Program, University of Washington; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Sydney A. Marsh
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Immunology Graduate Program, University of Washington; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Shannon M. Liudahl
raw_affiliation_strings: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Mari Hoffman
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Molecular and Cell Biology Graduate Program, University of Washington; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Lillian LeBlanc
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Madeleine E. Volfbeyn
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Sarah M. Garrison
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Megha Sarvothama
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Kevin C. Barry
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Mark B. Headley
raw_affiliation_strings: Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center
raw_author_name: Mario Marcondes
raw_affiliation_strings: Nektar Therapeutics; San Francisco, CA, USA
Nektar Therapeutics
raw_author_name: Shivani Srivastava
raw_affiliation_strings: Human Biology Division, Fred Hutchinson Cancer Center; Seattle, WA, USA
Fred Hutchinson Cancer Center