Comparative Analysis of AI-based Quantification vs. Visual Rating of Enlarged Perivascular Spaces in the MESA Cohort
Year: 2025
Type: article
Language: en
Topic: Cerebrospinal fluid and hydrocephalus
Authors and affiliations:
raw_author_name: Morgan F. Torres
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Sokratis Charisis
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Tanweer Rashid
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
raw_author_name: Sachintha R. Brandigampala
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
raw_author_name: Kevin D. Hiatt
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
raw_author_name: Jeffrey B. Ware
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Christopher T. Whitlow
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Ilya M. Nasrallah
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Jose Rafael Romero
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
raw_author_name: Jordan E. Tanley
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
raw_author_name: Sudha Seshadri
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Timothy J. Hohman
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Susan R. Heckbert
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Christos Davatzikos
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the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Timothy M. Hughes
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
raw_author_name: Mohamad Habes
raw_affiliation_strings: From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA; the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA; the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA; the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA; and the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of
the Department of Radiology (J.B.W., I.M.N., C.D.) and the Center for Biomedical Image Computing and Analytics (I.M.N., C.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
the Department of Epidemiology and Cardiovascular Health Research Unit (S.R.H.), University of Washington, Seattle, WA, USA
From the Neuroimage Analytics Laboratory (NAL) and the Biggs Institute Neuroimaging Core (BINC), Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases (M.F.T., S.C., T.R., S.R.B., S.S., M.H.), and the Department of Neurology (S.C., S.S.), University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
the Department of Neurology (R.R.), School of Medicine, Boston University, Boston, MA, USA
the Department of Radiology (K.D.H., C.T.W.), and the Department of Internal Medicine (J.E.T., T.M.H.), Wake Forest School of Medicine, Winston-Salem, NC, USA
the Vanderbilt Memory and Alzheimer's Center (T.H.), Vanderbilt University Medical Center, Nashville, TN, USA