A translational neuroscience &amp; computational evaluation of a D1R partial agonist for schizophrenia (TRANSCENDS): Rationale and study design of a brain-based clinical trial
Year: 2025
Type: article
Language: en
Topic: Neurotransmitter Receptor Influence on Behavior
Authors and affiliations:
raw_author_name: Clara Fonteneau
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Zailyn Tamayo
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Ally Price
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Lining Pan
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Yvette Afriyie-Agyemang
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Shriya Agrawal
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Audrey Butler
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Courtney Cail
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Monica Calkins
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Ananthsrinivas Rao Chakilam
raw_affiliation_strings: AbbVie Inc., North Chicago IL, USA
raw_author_name: Kimberlee Forselius-Bielen
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Geena Fram
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Allea Frazier
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Roberto Gil
raw_affiliation_strings: Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA
raw_author_name: Preetika Govil
raw_affiliation_strings: New York State Psychiatric Institute, New York NY, USA
raw_author_name: David L. Gray
raw_affiliation_strings: Vigil Neuroscience, Watertown MA, USA
raw_author_name: Jack Grinband
raw_affiliation_strings: New York State Psychiatric Institute, New York NY, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York NY, USA; Department of Radiology, Columbia University Irving Medical Center, New York NY, USA
raw_author_name: Ruben C. Gur
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Natalka K. Haubold
raw_affiliation_strings: Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA
raw_author_name: Zachary Heffernan
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Mara Heneks
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Larry Kegeles
raw_affiliation_strings: New York State Psychiatric Institute, New York NY, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York NY, USA
raw_author_name: Christian Kohler
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Chenyang Lin
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Jing Lu
raw_affiliation_strings: Investigational Drug Service, Yale New Haven Hospital, New Haven CT, USA
raw_author_name: Megan Mayer
raw_affiliation_strings: New York State Psychiatric Institute, New York NY, USA
raw_author_name: Phuong Pham
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Greg Perlman
raw_affiliation_strings: Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA
raw_author_name: Masih Rahmati
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Mohini Ranganathan
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; VA Connecticut Healthcare System, West Haven CT, USA
raw_author_name: Nicole P. Santamauro
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Christopher W. Schutte
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Alexandria Selloni
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Jared Van Snellenberg
raw_affiliation_strings: Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA
raw_author_name: Toral Surti
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; VA Connecticut Healthcare System, West Haven CT, USA
raw_author_name: Daniel H. Wolf
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Catrin Zharyy
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Anissa Abi-Dargham
raw_affiliation_strings: Department of Psychiatry, Stony Brook University Renaissance School of Medicine, Stony Brook NY, USA
raw_author_name: Raquel E. Gur
raw_affiliation_strings: Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia PA, USA
raw_author_name: Jeffrey A. Lieberman
raw_affiliation_strings: Columbia University, College of Physicians and Surgeons, New York NY, USA
raw_author_name: Joshua T. Kantrowitz
raw_affiliation_strings: New York State Psychiatric Institute, New York NY, USA; Columbia University, College of Physicians and Surgeons, New York NY, USA; Nathan Kline Institute, Orangeburg NY, USA
raw_author_name: Alan Anticevic
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA
raw_author_name: Youngsun T. Cho
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA; Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven CT, USA; Child Study Center, Yale University School of Medicine, New Haven CT, USA. Electronic address: youngsun.cho@yale.edu
raw_author_name: John H. Krystal
raw_affiliation_strings: Department of Psychiatry, Yale University School of Medicine, New Haven CT, USA