Multinational cost-utility analysis of panel-based pharmacogenetics-guided treatment of patients enrolled in the U-PGx PREPARE study
Year: 2025
Type: article
Language: en
Topic: Pharmacogenetics and Drug Metabolism
Authors and affiliations:
raw_author_name: Vasileios Fragoulakis
raw_affiliation_strings: The Golden Helix Foundation, London, UK
raw_author_name: Jesse J. Swen
raw_affiliation_strings: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands
raw_author_name: Margarita-Ioanna Koufaki
raw_affiliation_strings: The Golden Helix Foundation, London, UK
University of Patras, School of Health Sciences, Department of Pharmacy, Division of Pharmacology and Biosciences, Laboratory of Pharmacogenomics and Individualised Therapy, Patras, Greece
raw_author_name: Kathrin Blagec
raw_affiliation_strings: Centre for Medical Statistics, Informatics and Intelligent Systems, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria
raw_author_name: Tanja Blagus
raw_affiliation_strings: Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
raw_author_name: Stefan Böhringer
raw_affiliation_strings: Department of Biomedical Data Sciences, Leiden University Medical Centre, Leiden, Netherlands
The Golden Helix Foundation, London, UK
raw_author_name: Anne Cambon-Thomsen
raw_affiliation_strings: CNRS, Centre for Epidemiology and Research in Population Health (CERPOP), Université de Toulouse, INSERM, Toulouse, France
raw_author_name: Erika Cecchin
raw_affiliation_strings: Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
raw_author_name: Ka-Chun Cheung
raw_affiliation_strings: Medicines Information Centre, Royal Dutch Pharmacists Association (KNMP), The Hague, Netherlands
raw_author_name: Vera H.M. Deneer
raw_affiliation_strings: Division Laboratories, Pharmacy and Biomedical Genetics, Hospital Pharmacy, University Medical Centre Utrecht, Utrecht, Netherlands
Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Netherlands
raw_author_name: Mathilde Dupui
raw_affiliation_strings: Service de Pharmacologie Médicale et Clinique, CEIP-addictovigilance de Toulouse, Faculté de Médecine, CHU, Toulouse, France
raw_author_name: Siv Jonsson
raw_affiliation_strings: Department of Pharmacy, Uppsala University, Uppsala, Sweden
raw_author_name: Candace Joefield-Roka
raw_affiliation_strings: Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria
raw_author_name: Katja S. Just
raw_affiliation_strings: Institute of Clinical Pharmacology, University Hospital RWTH Aachen, Aachen, Germany
raw_author_name: Mats O. Karlsson
raw_affiliation_strings: Department of Pharmacy, Uppsala University, Uppsala, Sweden
raw_author_name: Lidija Konta
raw_affiliation_strings: Bio.logis Digital Health, Frankfurt am Main, Germany
Diagnosticum Centre for Humangenetics, Frankfurt am Main, Germany
raw_author_name: Rudolf Koopmann
raw_affiliation_strings: Bio.logis Digital Health, Frankfurt am Main, Germany
Diagnosticum Centre for Humangenetics, Frankfurt am Main, Germany
raw_author_name: Marjolein Kriek
raw_affiliation_strings: Department of Clinical Genetics, Leiden University Medical Centre, Leiden, Netherlands
raw_author_name: Thorsten Lehr
raw_affiliation_strings: Clinical Pharmacy, Saarland University, Saarbrücken, Germany
raw_author_name: Lisanne E.N. Manson
raw_affiliation_strings: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands
raw_author_name: Emmanuelle Rial-Sebbag
raw_affiliation_strings: Universite de Toulouse III Paul Sabatier, Toulouse, France
raw_author_name: Victoria Rollinson
raw_affiliation_strings: Department of Pharmacology and Therapeutics, Wolfson Centre for Personalised Medicine, The University of Liverpool, Liverpool, UK
raw_author_name: Rossana Roncato
raw_affiliation_strings: Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
raw_author_name: Matthias Samwald
raw_affiliation_strings: Centre for Medical Statistics, Informatics and Intelligent Systems, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria
raw_author_name: Elke Schaeffeler
raw_affiliation_strings: Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
iFIT Cluster of Excellence (EXC2180)-Image Guided and Functionally Instructed Tumor Therapies, University of Tuebingen, Tuebingen, Germany
raw_author_name: Maria Skokou
raw_affiliation_strings: University of Patras, School of Health Sciences, Department of Pharmacy, Division of Pharmacology and Biosciences, Laboratory of Pharmacogenomics and Individualised Therapy, Patras, Greece
raw_author_name: Matthias Schwab
raw_affiliation_strings: Department of Clinical Pharmacology, University of Tuebingen, Tuebingen, Germany
Department of Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany
Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
iFIT Cluster of Excellence (EXC2180)-Image Guided and Functionally Instructed Tumor Therapies, University of Tuebingen, Tuebingen, Germany
raw_author_name: Daniela Steinberger
raw_affiliation_strings: Bio.logis Digital Health, Frankfurt am Main, Germany
Diagnosticum Centre for Humangenetics, Frankfurt am Main, Germany
raw_author_name: Julia C. Stingl
raw_affiliation_strings: Department of Clinical Pharmacology and Pharmacoepidemiology, University Hospital Heidelberg, Germany
raw_author_name: Roman Tremmel
raw_affiliation_strings: Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
raw_author_name: Richard M. Turner
raw_affiliation_strings: Department of Pharmacology and Therapeutics, Wolfson Centre for Personalised Medicine, The University of Liverpool, Liverpool, UK
GSK, Stevenage, Hertfordshire, UK
raw_author_name: Mandy H. van Rhenen
raw_affiliation_strings: Medicines Information Centre, Royal Dutch Pharmacists Association (KNMP), The Hague, Netherlands
raw_author_name: Cathelijne H. van der Wouden
raw_affiliation_strings: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands
raw_author_name: Cristina Lucía Dávila-Fajardo
raw_affiliation_strings: Clinical Pharmacy Department, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria Granada, Granada, Spain
raw_author_name: Vita Dolžan
raw_affiliation_strings: Pharmacogenetics Laboratory, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
raw_author_name: Munir Pirmohamed
raw_affiliation_strings: Department of Pharmacology and Therapeutics, Wolfson Centre for Personalised Medicine, The University of Liverpool, Liverpool, UK
raw_author_name: Gere Sunder-Plassmann
raw_affiliation_strings: Department of Medicine III, Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria
raw_author_name: Giuseppe Toffoli
raw_affiliation_strings: Experimental and Clinical Pharmacology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
raw_author_name: Henk-Jan Guchelaar
raw_affiliation_strings: Department of Clinical Pharmacy and Toxicology, Leiden University Medical Centre, Leiden, Netherlands
raw_author_name: George P. Patrinos
raw_affiliation_strings: Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates
Erasmus University Medical Centre, Faculty of Medicine and Health Sciences, Department of Pathology-Clinical Bioinformatics Unit, Rotterdam, Netherlands
Hellenic Pasteur Institute, Athens, Greece
University of Patras, School of Health Sciences, Department of Pharmacy, Division of Pharmacology and Biosciences, Laboratory of Pharmacogenomics and Individualised Therapy, Patras, Greece
Zayed Centre for Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates
raw_author_name: Christina Mitropoulou
raw_affiliation_strings: Department of Genetics and Genomics, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, Abu Dhabi, United Arab Emirates
The Golden Helix Foundation, London, UK