A Population-Scale Single-Cell Atlas of the Human Heart Reveals Cellular Remodeling and Cell–Cell Communication in Aging and Cardiac Disease
Year: 2025
Type: article
Topic: Single-cell and spatial transcriptomics
Authors and affiliations:
raw_author_name: Zheng Gong
raw_affiliation_strings: Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China;
Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 25002, China
raw_author_name: Mengwei Li
raw_affiliation_strings: Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix Building, Level 7, Singapore 138671, Singapore;
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix Building, Level 7, Singapore 138671, Singapore
raw_author_name: Kok Siong Ang
raw_affiliation_strings: Centre for Computational Biology, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore;
Centre for Computational Biology, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore
raw_author_name: Xi Zhao
raw_affiliation_strings: Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China;
Key Laboratory of Endocrine Glucose & Lipids Metabolism and Brain Aging, Ministry of Education, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China
raw_author_name: Chrishan J Ramachandra
raw_affiliation_strings: National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore 169609, Singapore;
National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore 169609, Singapore
raw_author_name: Xiaomeng Wang
raw_affiliation_strings: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Singapore, 138673 Singapore;
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 1 Biopolis Drive, Singapore, 13873 Singapore
raw_author_name: Derek John Hausenloy
raw_affiliation_strings: Cardiovascular & Metabolic Disorders Program, Duke-NUS Medical School, Singapore 169857, Singapore;
Cardiovascular & Metabolic Disorders Program, Duke-NUS Medical School, Singapore 16985, Singapore
raw_author_name: Yibin Wang
raw_affiliation_strings: Signature Research Program in Cardiovascular and Metabolic Diseases, Duke-NUS Medical School & National Heart Research Institute, Singapore
raw_author_name: Yuguo Chen
raw_affiliation_strings: Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 250012, China;
Department of Emergency Medicine, Qilu Hospital of Shandong University, Jinan 25002, China
raw_author_name: Jinmiao Chen
raw_affiliation_strings: Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix Building, Level 7, Singapore 138671, Singapore;
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, Matrix Building, Level 7, Singapore 138671, Singapore