Molecular, histological, and clinical effects of selective TYK2 inhibition with zasocitinib (TAK-279) in patients with moderate-to-severe plaque psoriasis
Year: 2025
Type: article
Language: en
Topic: Psoriasis: Treatment and Pathogenesis
Authors and affiliations:
raw_author_name: Amit Choudhury
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA. Electronic address: amit.choudhury@takeda.com
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA. Electronic address: amit.choudhury@takeda.com
raw_author_name: Sandra Garcet
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
raw_author_name: Inna Cueto
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
raw_author_name: Norma Kunjravia
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
raw_author_name: Xuan Li
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
raw_author_name: Darshna Rambhia
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA
raw_author_name: Sachin Kumar
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Vinayagam Arunachalam
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Jessamyn Blau
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Jie Cheng
raw_affiliation_strings: Statistical and Quantitative Sciences, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Statistical and Quantitative Sciences, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Feng Hong
raw_affiliation_strings: Statistical and Quantitative Sciences, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Statistical and Quantitative Sciences, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Banishree Saha
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Jay Tang
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Wenwen Zhang
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Håkan Wennbo
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: Paresh Thakker
raw_affiliation_strings: Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA
Gastrointestinal and Inflammation Therapeutic Area Unit, Takeda Pharmaceuticals International Co., Cambridge, MA, USA
raw_author_name: James G. Krueger
raw_affiliation_strings: Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York, USA
Laboratory for Investigative Dermatology, The Rockefeller University, New York, NY, USA