Plasma cell identity escape drives resistance to anti-BCMA T-cell–redirecting therapy in multiple myeloma
Year: 2025
Type: preprint
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Francesco Maura
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA
raw_author_name: Ciara L. Freeman
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Kylee H Maclachlan
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Marta Larrayoz Ilundain
raw_affiliation_strings: Department of Hematology, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, IDISNA, CIBERONC, University of Navarra, Pamplona, Spain
raw_author_name: Bachisio Ziccheddu
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Erin W Meermeier
raw_affiliation_strings: Mayo Clinic, Scottsdale, AZ, USA
raw_author_name: Juan-Jose Garces
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Michael Durante
raw_affiliation_strings: Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA
raw_author_name: Holly Lee
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Ross Firestone
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Meghan Menges
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Kayla Reid
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Benjamin Diamond
raw_affiliation_strings: Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA
raw_author_name: Marios Papadimitriou
raw_affiliation_strings: Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA
raw_author_name: Ariosto Siqueira Silva
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Praneeth Reddy Sudalagunta
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Noemie Leblay
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Sungwoo Ahn
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Ethan Fuller
raw_affiliation_strings: Dana Farber Cancer Institute, Boston, USA
raw_author_name: Edward Briercheck
raw_affiliation_strings: Dana Farber Cancer Institute, Boston, USA
raw_author_name: Meaghen E Sharik
raw_affiliation_strings: Mayo Clinic, Scottsdale, AZ, USA
raw_author_name: Megan T Du
raw_affiliation_strings: Mayo Clinic, Scottsdale, AZ, USA
raw_author_name: Phaedra Agius
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Doris K Hansen
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Xiaofei Song
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Xiaohong Zhao
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Mark B Meads
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Jamie Teer
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Tomas Jelinek
raw_affiliation_strings: Department of Haemato-oncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
raw_author_name: Patrick Hagner
raw_affiliation_strings: Executive Director, Translational Development, Bristol-Myers Squibb, Summit, NJ 07901
Executive Director, Translational Development, Bristol-Myers Squibb, Summit, NJ 0701
raw_author_name: Rachid Baz
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Melissa Alsina
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Anusuya M. Ramasubramanian
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Eric Smith
raw_affiliation_strings: Dana Farber Cancer Institute, Boston, USA
raw_author_name: Sergio A. Giralt
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Sham Mailankody
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Leif P. Bergsagel
raw_affiliation_strings: Mayo Clinic, Scottsdale, AZ, USA
raw_author_name: Paola Neri
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Marta Chesi
raw_affiliation_strings: Mayo Clinic, Scottsdale, AZ, USA
raw_author_name: Jose A. Martinez-Climent
raw_affiliation_strings: Department of Hematology, Center for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, IDISNA, CIBERONC, University of Navarra, Pamplona, Spain
raw_author_name: Frederick L. Locke
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA
raw_author_name: Nizar J. Bahlis
raw_affiliation_strings: Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, Canada
raw_author_name: Ola Landgren
raw_affiliation_strings: Myeloma Service, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, USA
raw_author_name: Issam Hamadeh
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Saad Z. Usmani
raw_affiliation_strings: Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Kenneth H. Shain
raw_affiliation_strings: Moffitt Cancer Center, Tampa, FL, USA