Targeting E2F8 sensitizes gemcitabine-resistant gallbladder cancer to PARP inhibitors by disrupting RRM2-driven DNA repair
Year: 2025
Type: article
Language: en
Topic: Cholangiocarcinoma and Gallbladder Cancer Studies
Authors and affiliations:
raw_author_name: Xiaojian Ni
raw_affiliation_strings: Biliary Tract Disease Center of Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Shanghai Biliary Tract Minimal Invasive Surgery and Materials Engineering Research Center, Shanghai, 200032, China
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China
raw_author_name: Min Li
raw_affiliation_strings: Biliary Tract Disease Center of Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Shanghai Biliary Tract Minimal Invasive Surgery and Materials Engineering Research Center, Shanghai, 200032, China
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China
raw_author_name: Wenqing Qiu
raw_affiliation_strings: Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China
raw_author_name: Jichang Han
raw_affiliation_strings: School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China
Sylvester Comprehensive Cancer Center, University of Miami, Miller Scholl of Medicine, Miami, FL, 33136, USA
raw_author_name: Meng Yu
raw_affiliation_strings: School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China
Sylvester Comprehensive Cancer Center, University of Miami, Miller Scholl of Medicine, Miami, FL, 33136, USA
raw_author_name: Shulong Zhang
raw_affiliation_strings: Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China
raw_author_name: Bohao Zheng
raw_affiliation_strings: Biliary Tract Disease Center of Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China
Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Shanghai Biliary Tract Minimal Invasive Surgery and Materials Engineering Research Center, Shanghai, 200032, China
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China
raw_author_name: Jiaqi He
raw_affiliation_strings: General Surgery, Department of Huadong Hospital, Fudan University, Shanghai, 200040, China. hd_hejiaqi@163.com
General Surgery, Department of Huadong Hospital, Fudan University, Shanghai, 200040, China
raw_author_name: Houbao Liu
raw_affiliation_strings: Biliary Tract Disease Center of Zhongshan Hospital, Fudan University, Shanghai, 200030, China. zsliuhb@sina.cn
Cancer Center, Zhongshan Hospital, Fudan University, Shanghai, 200030, China. zsliuhb@sina.cn
Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China. zsliuhb@sina.cn
Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China. zsliuhb@sina.cn
Shanghai Biliary Tract Minimal Invasive Surgery and Materials Engineering Research Center, Shanghai, 200032, China. zsliuhb@sina.cn
Zhongshan-Xuhui Hospital, Fudan University, Shanghai, 200032, China. zsliuhb@sina.cn
Shanghai Biliary Tract Minimal Invasive Surgery and Materials Engineering Research Center, Shanghai, 200032, China
Department of General Surgery, Shanghai Xuhui Central Hospital, Shanghai, 200031, China
Department of Biliary Surgery, Zhongshan Hospital, Fudan University, Shanghai, 200030, China