Selective depletion of tumor-associated SAMHD1 enhances chemotherapeutic efficacy and antitumor immune responses
Year: 2025
Type: article
Language: en
Topic: interferon and immune responses
Authors and affiliations:
raw_author_name: Jing Sun
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
Yale School of Medicine, Yale University, New Haven, CT, USA
raw_author_name: Wenwen Zheng
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Zheng-Guo Zhang
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Hongkun Zhou
raw_affiliation_strings: Department of Hepatobiliary Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, China
raw_author_name: Songdi Wang
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Dingbo Huang
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Xiao-Yi Hu
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Qing-Feng Yu
raw_affiliation_strings: Department of Hematology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Zhao-Xing Wu
raw_affiliation_strings: Department of Hematology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Yi-Fei Shi
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Runxin Ye
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Fengyan Xia
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Wangwei Li
raw_affiliation_strings: School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China
raw_author_name: Shurui Lyu
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Yu Huang
raw_affiliation_strings: Experimental Animal Research Center, Zhejiang Chinese Medical University, Hangzhou, China
raw_author_name: Xu-Zhao Zhang
raw_affiliation_strings: Department of Hematology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Fei Xu
raw_affiliation_strings: Department of Hematology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Ke Zhao
raw_affiliation_strings: Institute of Virology and AIDS Research, First Hospital of Jilin University, Changchun, China
raw_author_name: Jie Yang
raw_affiliation_strings: Department of Hepatobiliary Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, China
raw_author_name: Juan Du
raw_affiliation_strings: Institute of Virology and AIDS Research, First Hospital of Jilin University, Changchun, China
raw_author_name: Jiaming Su
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Yajuan Rui
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Rongzhen Xu
raw_affiliation_strings: Department of Hematology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Wei-Ming Yang
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA
raw_author_name: Cang Li
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Jia ling Xu
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
raw_author_name: Ruiyu Zhu
raw_affiliation_strings: College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, China
School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China
raw_author_name: Xiaoguang Wang
raw_affiliation_strings: Department of Hepatobiliary Surgery, Affiliated Hospital of Jiaxing University, Jiaxing, China. xiaoguangwangs@163.com
raw_author_name: Wei Wei
raw_affiliation_strings: Cancer Center, The First Hospital of Jilin University, Changchun, Jilin, China. wwei6@jlu.edu.cn
Institute of Translational Medicine, Key Laboratory of Organ Regeneration and Transplantation of Ministry of Education, The First Hospital of Jilin University, Changchun, Jilin, China. wwei6@jlu.edu.cn
Institute of Virology and AIDS Research, First Hospital of Jilin University, Changchun, China. wwei6@jlu.edu.cn
raw_author_name: Xiao-Fang Yu
raw_affiliation_strings: Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education), The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. xfyu1@zju.edu.cn