Endothelial mitochondrial-derived vesicles (EMDVs) with retinal targeted homing properties dynamically modulate the eIF2α-ATF4-CHOP signaling pathway and efficiently restore mitochondrial homeostasis in diabetic retina
Year: 2025
Type: article
Language: en
Topic: Nanoplatforms for cancer theranostics
Authors and affiliations:
raw_author_name: Siyu Gui
raw_affiliation_strings: Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
National Clinical Research Center for Eye Diseases, Shanghai, China
Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
Shanghai Gene Therapy Center, Shanghai, China
Shanghai Key Laboratory of Fundus Diseases, Shanghai, China
raw_author_name: Jie Gao
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
raw_author_name: Tianchang Tao
raw_affiliation_strings: Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
raw_author_name: Peng Wang
raw_affiliation_strings: Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
National Clinical Research Center for Eye Diseases, Shanghai, China
Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
Shanghai Gene Therapy Center, Shanghai, China
Shanghai Key Laboratory of Fundus Diseases, Shanghai, China
raw_author_name: Yueyang Xu
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
raw_author_name: Zhihao Huang
raw_affiliation_strings: Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
National Clinical Research Center for Eye Diseases, Shanghai, China
Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
Shanghai Gene Therapy Center, Shanghai, China
Shanghai Key Laboratory of Fundus Diseases, Shanghai, China
raw_author_name: Yuyang She
raw_affiliation_strings: Department of Clinical Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Jiajie Li
raw_affiliation_strings: Department of Clinical Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Jingwan Su
raw_affiliation_strings: School of Ophthalmology & Optometry, Wenzhou Medical University, Wenzhou, 325000, China
raw_author_name: Zhe Lu
raw_affiliation_strings: School of Optometry & Ophthalmology, Tianjin Medical University, Tianjin, 300070, China
raw_author_name: Jianchao Qiao
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
raw_author_name: Song Wang
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China. gnawgnos@163.com
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China
raw_author_name: Xiaodong Sun
raw_affiliation_strings: Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. xdsun@sjtu.edu.cn
National Clinical Research Center for Eye Diseases, Shanghai, China. xdsun@sjtu.edu.cn
Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China. xdsun@sjtu.edu.cn
Shanghai Gene Therapy Center, Shanghai, China. xdsun@sjtu.edu.cn
Shanghai Key Laboratory of Fundus Diseases, Shanghai, China. xdsun@sjtu.edu.cn
National Clinical Research Center for Eye Diseases, Shanghai, China
Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Mohan Li
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China. limohan@ahmu.edu.cn
Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China