Design and Evaluation of a Folate-Targeted PEG-MMAE Conjugate with Enzyme-Activated Drug Release for Enhanced Tumor Selectivity and Antitumor Efficacy
Year: 2025
Type: article
Language: en
Topic: Nanoparticle-Based Drug Delivery
Authors and affiliations:
raw_author_name: Lizhe Bai
raw_affiliation_strings: East China Normal University
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering
raw_author_name: Xuzhuo Li
raw_affiliation_strings: East China Normal University
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering
raw_author_name: Chengyi Zuo
raw_affiliation_strings: Institute of Pharmaceutical Analysis, College of pharmacy/State Key Laboratory of Bioactive Molecules and Druggability assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China
Jinan University
Institute of Pharmaceutical Analysis, College of pharmacy/State Key Laboratory of Bioactive Molecules and Druggability assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China
raw_author_name: Mengyuan Ding
raw_affiliation_strings: East China Normal University
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China
raw_author_name: Xing Jiang
raw_affiliation_strings: East China Normal University
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering
raw_author_name: Wei Lu
raw_affiliation_strings: East China Normal University
School of Pharmacy, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering
Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China
raw_author_name: Qiqin Wang
raw_affiliation_strings: Institute of Pharmaceutical Analysis, College of pharmacy/State Key Laboratory of Bioactive Molecules and Druggability assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China
Jinan University
Institute of Pharmaceutical Analysis, College of pharmacy/State Key Laboratory of Bioactive Molecules and Druggability assessment/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China, Jinan University, Guangzhou 510632, China
raw_author_name: Shulei Zhu
raw_affiliation_strings: School of Pharmacy, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062, China