Phosphorylation of CBX8 by PKD1 suppresses PRC1 activity and promotes cell senescence
Year: 2025
Type: article
Language: en
Topic: Epigenetics and DNA Methylation
Authors and affiliations:
raw_author_name: Zhiqiang Fang
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
raw_author_name: Doudou Liu
raw_affiliation_strings: Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
raw_author_name: Yuanyuan Su
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
Xiamen Key Laboratory of Precision Medicine for Cardiovascular Disease, Xiamen, China
raw_author_name: Fengxin Hao
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
raw_author_name: Ruodong Qin
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
raw_author_name: Guodong Li
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China
raw_author_name: Jun Chen
raw_affiliation_strings: Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China. cjbiochem@bjmu.edu.cn
Peking University Research Center on Aging, Department of Biochemistry and Molecular Biology, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Department of Integration of Chinese and Western Medicine, School of Basic Medical Science, Peking University, Beijing, 100191, China