Complete structures of the YenTc holotoxin prepore and pore reveal the evolutionary basis for chitinase incorporation into ABC toxins
Year: 2025
Type: article
Language: en
Topic: Studies on Chitinases and Chitosanases
Authors and affiliations:
raw_author_name: Yu Shang Low
raw_affiliation_strings: ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Solace G. Roche
raw_affiliation_strings: ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Nadezhda A. Aleksandrova
raw_affiliation_strings: ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Gabriel Foley
raw_affiliation_strings: School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Jason KK Low
raw_affiliation_strings: School of Life and Environmental Sciences, University of Sydney, Camperdown, NSW, Australia
raw_author_name: Joseph K. Box
raw_affiliation_strings: School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Tristan I. Croll
raw_affiliation_strings: Altos Labs, Cambridge, UK
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK
raw_author_name: Irene R. Chassagnon
raw_affiliation_strings: School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
Servatus Biopharmaceuticals, Coolum Beach, QLD, Australia
raw_author_name: J. Shaun Lott
raw_affiliation_strings: School of Biological Sciences, University of Auckland, Auckland, New Zealand
raw_author_name: Evelyne Deplazes
raw_affiliation_strings: School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Mikael Bodén
raw_affiliation_strings: School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia
raw_author_name: Mark RH Hurst
raw_affiliation_strings: Bioeconomy Science Institute, AgResearch, Lincoln Research Centre, Christchurch, New Zealand
raw_author_name: Sarah J. Piper
raw_affiliation_strings: ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au
Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. sarah.piper@monash.edu.au
Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. sarah.piper@monash.edu.au
raw_author_name: Michael J. Landsberg
raw_affiliation_strings: ARC Centre for Cryo-electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. m.landsberg@uq.edu.au
Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au
School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, Australia. m.landsberg@uq.edu.au