c-Rel drives pancreatic cancer metastasis through fibronectin-integrin signaling-induced isolation stress resistance and EMT
Year: 2025
Type: article
Language: en
Topic: Cell Adhesion Molecules Research
Authors and affiliations:
raw_author_name: D. Bakırdöğen
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany. derya.kabacaoglu@tum.de
Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: K. Görgülü
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: J. Xin
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: L. Richter
raw_affiliation_strings: Department of Surgery, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany
raw_author_name: S. Alcalá
raw_affiliation_strings: Biomarkers and Personalized Approach to Cancer Group (BIOPAC), Area 3 Cancer, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, 28049, Spain
Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Cancer Department, Instituto de Investigaciones Biomédicas (IIBM) Sols-Morreale CSIC-UAM, Madrid, Spain
raw_author_name: L. Ruiz-Cañas
raw_affiliation_strings: Biomarkers and Personalized Approach to Cancer Group (BIOPAC), Area 3 Cancer, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, 28049, Spain
Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Cancer Department, Instituto de Investigaciones Biomédicas (IIBM) Sols-Morreale CSIC-UAM, Madrid, Spain
raw_author_name: C. Dai
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: K. J. Frank
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: N. Wu
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: K. N. Diakopoulos
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: H. Ozturk
raw_affiliation_strings: Department of Obstetrics and Gynecology, Robert Lurie Comprehensive Cancer Center, Feinberg School of Medicine at Northwestern University, Chicago, IL, USA
raw_author_name: D. Demircioğlu
raw_affiliation_strings: Bioinformatics for Next-Generation Sequencing (BiNGS) core, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA
raw_author_name: K. Peschke
raw_affiliation_strings: Center for Organoid Systems (COS), Technical University of Munich, Munich, Germany
Center for Protein Assemblies (CPA), Technical University of Munich, Munich, Germany
German Cancer Consortium (DKTK), partner site Munich, Munich, Germany
TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
Translational Pancreatic Cancer Research Center, TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
Translational Pancreatic Cancer Research Center, TUM School of Medicine and Health, Department of Clinical Medicine – Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
raw_author_name: R. Ranjan
raw_affiliation_strings: Center for Organoid Systems (COS), Technical University of Munich, Munich, Germany
Center for Protein Assemblies (CPA), Technical University of Munich, Munich, Germany
German Cancer Consortium (DKTK), partner site Munich, Munich, Germany
TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
Translational Pancreatic Cancer Research Center, TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
raw_author_name: F. Fusco
raw_affiliation_strings: Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany
raw_author_name: J. Martinez-Useros
raw_affiliation_strings: Area of Physiology, Department of Basic Health Sciences, Faculty of Health Sciences, Rey Juan Carlos University, Madrid, 28922, Spain
Translational Oncology Division, Oncohealth Institute, Fundacion Jiménez Díaz University Hospital, Madrid, 28040, Spain
raw_author_name: M. J. Fernandez-Aceñero
raw_affiliation_strings: Pathology Department, Clinico San Carlos University Hospital, Madrid, 28040, Spain
raw_author_name: N. F. Chhabra
raw_affiliation_strings: TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
TUM School of Medicine and Health, Department of Clinical Medicine – Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
raw_author_name: J. C. López-Gil
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Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Cancer Department, Instituto de Investigaciones Biomédicas (IIBM) Sols-Morreale CSIC-UAM, Madrid, Spain
raw_author_name: J. Ai
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, China
Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Cancer Department, Instituto de Investigaciones Biomédicas (IIBM) Sols-Morreale CSIC-UAM, Madrid, Spain
Biomarkers and Personalized Approach to Cancer Group (BIOPAC), Area 3 Cancer, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, 28049, Spain
raw_author_name: D. A. Ruess
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
Department of General and Visceral Surgery, Center for Surgery, Medical Center University of Freiburg, Freiburg, Germany
German Cancer Consortium (DKTK), Partner Site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany
raw_author_name: E. Kaya-Aksoy
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: F. Schmidt
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: L. Kohlmann
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: A. Berninger
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: H. Yang
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany
raw_author_name: F. Schicktanz
raw_affiliation_strings: Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany
raw_author_name: K. Steiger
raw_affiliation_strings: Institute of Pathology, School of Medicine, Technical University of Munich, Munich, Germany
raw_author_name: I. E. Demir
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raw_author_name: R. M. Schmid
raw_affiliation_strings: TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
TUM School of Medicine and Health, Department of Clinical Medicine – Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
raw_author_name: M. Reichert
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Center for Organoid Systems (COS), Technical University of Munich, Munich, Germany
Center for Protein Assemblies (CPA), Technical University of Munich, Munich, Germany
German Cancer Consortium (DKTK), partner site Munich, Munich, Germany
TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
Translational Pancreatic Cancer Research Center, TUM School of Medicine and Health, Department of Clinical Medicine - Clinical Department for Internal Medicine II, University Medical Center, Technical University of Munich, Munich, Germany
raw_author_name: M. Adli
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raw_author_name: M. Lesina
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raw_author_name: B. Sainz
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Cancer Stem Cells and Fibroinflammatory Microenvironment Group, Cancer Department, Instituto de Investigaciones Biomédicas (IIBM) Sols-Morreale CSIC-UAM, Madrid, Spain
Centro de Investigación Biomédica en Red, Área Cáncer, CIBERONC, ISCIII, Madrid, Spain
raw_author_name: H. Algül
raw_affiliation_strings: Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany. hana.alguel@mri.tum.de
Comprehensive Cancer Center München, Institute for Tumor Metabolism, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, Ismaninger Str. 22, Munich, 81675, Germany