Long‐Term Outcomes of a Stratified Treatment Regimen Based on Etoposide and Glucocorticoids in Children With Hemophagocytic Lymphohistiocytosis ( <scp>CCHG</scp> ‐ <scp>HLH</scp> ‐2018): A Multicenter, Single‐Arm Clinical Study
Year: 2025
Type: article
Language: en
Topic: Autoimmune and Inflammatory Disorders Research
Authors and affiliations:
raw_author_name: Zishi Fang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
raw_author_name: Jie Yu
raw_affiliation_strings: Department of Hematology Oncology Children's Hospital of Chongqing Medical University  Chongqing China
Department of Hematology Oncology, Children's Hospital of Chongqing Medical University, Chongqing, China
raw_author_name: Wei Liu
raw_affiliation_strings: Department of Hematology Oncology Children's Hospital of Zhengzhou University  Zhengzhou Henan China
Department of Hematology Oncology, Children's Hospital of Zhengzhou University, Zhengzhou, Henan, China
raw_author_name: Ang Wei
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: Qing Zhang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematologic Disease Laboratory Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Hematologic Disease Laboratory, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Capital Medical University, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
raw_author_name: Jianpei Fang
raw_affiliation_strings: Department of Pediatrics Sun Yat‐sen Memorial Hospital, Sun Yat‐sen University  Guangzhou Province China
Department of Pediatrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Province, China
raw_author_name: Shaoyan Hu
raw_affiliation_strings: Department of Hematology Children's Hospital of Soochow University  Soochow Province China
Department of Hematology, Children's Hospital of Soochow University, Soochow, Province, China
raw_author_name: Xiaoyan Wu
raw_affiliation_strings: Department of Pediatrics, Union Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan Hubei China
Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
raw_author_name: Jian Wang
raw_affiliation_strings: Department of Hematology Oncology Anhui Children's Hospital  Hefei Anhui China
Department of Hematology, Beijing Friendship Hospital Capital Medical University  Beijing China
Department of Hematology Oncology, Anhui Children's Hospital, Hefei, Anhui, China
raw_author_name: Weihong Zhao
raw_affiliation_strings: Department of Pediatrics, First Hospital Peking University  Beijing China
Department of Pediatrics, First Hospital, Peking University, Beijing, China
raw_author_name: Aiguo Liu
raw_affiliation_strings: Department of Pediatric Hematology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology  Wuhan Province China
Department of Pediatric Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Province, China
raw_author_name: Shilin Liu
raw_affiliation_strings: Department of Hematology Oncology Shenzhen Children's Hospital  Shenzhen China
Department of Hematology Oncology, Shenzhen Children's Hospital, Shenzhen, China
raw_author_name: Xuerong Li
raw_affiliation_strings: Department of Pediatric Hematology and Oncology The Affiliated Hospital of Qingdao University  Qingdao China
Department of Pediatric Hematology and Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China
raw_author_name: Yongjun Fang
raw_affiliation_strings: Department of Hematology and Oncology Children's Hospital of Nanjing Medical University  Nanjing China
Department of Hematology and Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China
raw_author_name: Jingshi Wang
raw_affiliation_strings: Department of Hematology Oncology Anhui Children's Hospital  Hefei Anhui China
Department of Hematology, Beijing Friendship Hospital Capital Medical University  Beijing China
Department of Hematology, Beijing Friendship Hospital, Capital Medical University, Beijing, China
raw_author_name: Yuan Sun
raw_affiliation_strings: Department of Hematology Oncology Beijing Jingdu Children's Hospital  Beijing China
Department of Hematology Oncology, Beijing Jingdu Children's Hospital, Beijing, China
raw_author_name: Rong Liu
raw_affiliation_strings: Department of Hematology Children's Hospital Affiliated to Capital Institute of Pediatrics  Beijing China
Department of Hematology, Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing, China
raw_author_name: Leping Zhang
raw_affiliation_strings: Department of Pediatrics Peking University People's Hospital  Beijing China
Department of Pediatrics, Peking University People's Hospital, Beijing, China
raw_author_name: Yongmin Tang
raw_affiliation_strings: Hematology‐Oncology Center, The Children's Hospital of Zhejiang University School of Medicine  Hangzhou Zhejiang China
Hematology-Oncology Center, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
raw_author_name: Dongsheng Huang
raw_affiliation_strings: Department of Pediatrics Beijing Tongren Hospital, Capital Medical University  Beijing China
Department of Pediatrics, Beijing Tongren Hospital, Capital Medical University, Beijing, China
raw_author_name: Xiaojun Yuan
raw_affiliation_strings: Department of Pediatric Hematology and Oncology Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine  Shanghai China
Department of Pediatric Hematology and Oncology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Liming Sun
raw_affiliation_strings: Department of Pediatrics, Beijing Shijitan Hospital Capital Medical University  Beijing China
Department of Pediatrics, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
raw_author_name: Jian Ge
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
raw_author_name: Yunze Zhao
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: Dong Wang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: Wenqian Wang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
raw_author_name: Chenxin Zhou
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
raw_author_name: Zhigang Li
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematologic Disease Laboratory Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics, Capital Medical University, Beijing, China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematologic Disease Laboratory, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: Tianyou Wang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: Rui Zhang
raw_affiliation_strings: Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics Capital Medical University  Beijing China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education  Beijing China
Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing, China
Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China
raw_author_name: for the Chinese Children's Histiocyte Group