Tubule‐Derived IFN‐α Promotes GSDMD‐Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation
Year: 2025
Type: article
Language: en
Topic: Inflammasome and immune disorders
Authors and affiliations:
raw_author_name: Yiping Xu
raw_affiliation_strings: Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
raw_author_name: Yating Wang
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
raw_author_name: Siming Jiang
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
raw_author_name: Yi Li
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
raw_author_name: Guanglan Li
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
raw_author_name: Yuchu Liu
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
raw_author_name: Siyuan Li
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
raw_author_name: Yiming Zhou
raw_affiliation_strings: Basic andTranslational Medical Research Center, Sun Yat-sen Memorial Hospital Sun Yat‐sen University  Guangzhou 510120 China
Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Basic andTranslational Medical Research Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510120 China
raw_author_name: Qinghua Liu
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
raw_author_name: Yi Zhou
raw_affiliation_strings: Basic andTranslational Medical Research Center, Sun Yat-sen Memorial Hospital Sun Yat‐sen University  Guangzhou 510120 China
Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
raw_author_name: Wei Chen
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Email: [email protected]
raw_author_name: Hongyu Li
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China
Email: [email protected]
raw_author_name: Haiping Mao
raw_affiliation_strings: Department of Nephrology NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology  Guangzhou 510080 China
Department of Nephrology The First Affiliated Hospital Sun Yat‐sen University  Guangzhou 510080 China
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080 China
Email: [email protected]
Department of Nephrology, NHC Key Laboratory of ClinicalNephrology (Sun Yat-Sen University) and Guangdong Provincial Key Laboratory ofNephrology, Guangzhou, 510080 China