LabID-base/OpenAlex-Afillation huggingface dataset:
MICROFLUIDIC PLATFORM TO UNRAVEL GLIOMASECRETOME INTERACTION
Year: 2025
Type: article
Language: en
Topic: 3D Printing in Biomedical Research
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Diffuse infiltrating gliomas (DIGs) account for approximately 80% of all malignant gliomas, making them the second most common primary tumor of the central nervous system (CNS). Among them, glioblastoma (GBM) is the most aggressive form, associated with poor prognosis. These features are attributed to the interplay between clonogenic glioblastoma stem cells (GSCs) and the tumor microenvironment (TME). In fact, the secretion of growth factors and cytokines supports GSCs, collectively altering the tumor secretome that maintains cancer cell pluripotency, drives invasiveness, facilitates intra-brain tumor dissemination, and conferrers resistance to chemotherapy. The goal of this study is to develop a novel approach to investigate the interplay between GSCs and secretome through an in vitro microfluidic system, through the MIVO platform organ-on-chip. To this aim, tumor spheres of different glioma cell lines were cultured using the hanging drop method and moved to the upper chamber of MIVO support: a compartment divided from the fluidic channel by a porous membrane, simulating the microcirculation of secreted cells in the TME. A volume of 150-200 μL of medium was added into the chamber to balance the liquid level inside and outside the insert, to ensure proper flow. The plate with the inserts was placed in the specific support, then the cartridge was secured inside the pump head. To validate the platform’s potential, deferoxamine (DFX, a hypoxiamimetic agent) was added to the flow of the microfluidic system, worsening the tumor microenvironment. In this contest, DFX effects on the secretome were evaluated by ELISA assay. Preliminary results revealed a significant increase of vascular endothelial growth factor (VEGF) and interleukin-1β (IL-1β) in glioma secretomes following DFX exposure, observing some differences among glioma cell lines. These findings support our hypothesis by this microfluidic platform is able to offer a valuable tool for studying GSC behavior during therapeutic interventions. Furthermore, it holds promise for use in preliminary screening of therapeutic agents targeting DIGs, potentially accelerating drug discovery and improving treatment strategies. This study was supported by Piano di Incentivi per la Ricerca di Ateneo 2024/2026. Linea di intervento 1
The effect of addition of methionine and lysine in rations containing fermented palm kernel cake on broiler protein efficiency ratio
Year: 2025
Type: article
Language: id
Topic: Food and Agricultural Sciences
Authors and affiliations:
raw_author_name: M. Alfarizi
raw_affiliation_strings: Universitas Jambi, Jambi, Indonesia
raw_author_name: Mairizal Mairizal
raw_affiliation_strings: Universitas Jambi, Jambi, Indonesia
raw_author_name: Akmal Akmal
raw_affiliation_strings: Universitas Jambi, Jambi, Indonesia
Pemantauan Kondisi Fisik Bendungan Sermo Bertipe Beton Melalui Model Tiga Dimensi Menggunakan Unmanned Aerial Vehicle
Year: 2025
Type: article
Topic: Infrastructure Maintenance and Monitoring
Authors and affiliations:
raw_author_name: Tiara Alda Megapratiwi
raw_affiliation_strings: Universitas Pembangunan Nasional "Veteran" Yogyakarta
raw_author_name: Maulana Yudinugroho
raw_affiliation_strings: Teknik Geomatika, Fakultas Teknologi Mineral & Energi, Universitas Pembangunan Nasional “Veteran” Yogyakarta, Indonesia
Teknik Geomatika, Fakultas Teknologi Mineral & Energi, Universitas Pembangunan Nasional "Veteran" Yogyakarta, Indonesia
OVEREXPRESSION OF ANOSMIN-1 ALTERS THE MYELINATION PATTERN AND THE MORPHOLOGY OF AXONAL COMPONENTS IN CEREBELLAR PURKINJE CELLS
Year: 2025
Type: article
Language: en
Topic: Hypothalamic control of reproductive hormones
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Anosmin-1 (A1) is an extracellular matrix glycoprotein that regulates FGF, Wnt, BMP, and VEGF signaling pathways during nervous system development, and is widely expressed throughout the central nervous system, including the cerebellum. Mutations in the ANOS1 gene (formerly KAL1), which encodes A1, cause Kallmann syndrome (KS), a rare congenital disorder characterized by hypogonadotropic hypogonadism and anosmia. Given that the A1-overexpressing mouse model exhibits ataxia-like motor deficits, we hypothesized that these abnormalities might result from cerebellar dysfunction. Alterations in myelin formation and in the structural components of axons are major contributors to both the generation and conduction velocity of action potentials and may represent a key mechanism underlying the motor impairments observed in A1-overexpressing mice. To investigate this possibility, we examined the maturation dynamics of the axon initial segment (AIS) and the overall myelination pattern. Immunostaining of Ankyrin-g, a reliable marker of the AIS, revealed distinct morphological modifications in Purkinje cell axons of A1-overexpressing mice. Specifically, AISs in mutant mice are significantly longer and located further away from the soma compared to wild-type (WT) controls at adult stages. To assess potential structural modifications in the nodal and paranodal regions, we measured the length of nodes of Ranvier and found that, at postnatal day 60, mutant mice displayed longer nodes compared to WT. Moreover, during development, A1-overexpressing mice exhibited an altered timeline of myelination with evidence that the deposition occurs earlier compared to WT. Yet, in the mutants myelination reaches normal levels at adult stages. These data indicate that A1 regulates both the timing of myelin deposition and the structural organization of axonal domains, thereby participating in the neuromorphological shaping of Purkinje cell axons essential for efficient signal transmission
Taxonomy, morphology and cytology of Micranthes virginiensis (Michaux) Small (Saxifragales, Saxifragaceae), new chromosome counts for Micranthes and description of a new Micranthes species from the south-eastern USA
Year: 2025
Type: article
Language: en
Topic: Plant Diversity and Evolution
Authors and affiliations:
raw_author_name: Tara K. Hall
raw_affiliation_strings: Western Carolina University, Cullowhee, United States of America
raw_author_name: Luiz F. L. da Silveira
raw_affiliation_strings: Western Carolina University, Cullowhee, United States of America
raw_author_name: Max S. Lanning
raw_affiliation_strings: Western Carolina University, Cullowhee, United States of America
raw_author_name: Katherine G. Mathews
raw_affiliation_strings: Western Carolina University, Cullowhee, United States of America
KAEMPFEROL TARGETS LIPID BALANCE, ENDOCANNABINOID PATHWAYS, AND PPAR-α IN THE RAT CEREBRAL CORTEX AFTER TRANSIENT BILATERAL COMMON CAROTID ARTERY OCCLUSION AND REPERFUSION
Year: 2025
Type: article
Language: en
Topic: Cannabis and Cannabinoid Research
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Transient bilateral common carotid artery occlusion and reperfusion (BCCAO/R) has previously been established as an effective model for replicating early brain inflammation triggered by acute hypoperfusion and subsequent reperfusion events. Recognizing the significant role of diet and nutrition in shaping brain neuroplasticity, this investigation explored the neuroprotective impact of kaempferol (KAM), a dietary flavonoid, within a rat BCCAO/R paradigm. Adult Wistar rats received a single oral dose of KAM (40 mg) 6 h prior to surgery. Extensive lipidomic and molecular assessments were performed on frontal and temporal-occipital cortical tissues in addition to plasma samples. In the frontal cortex, KAM treatment led to increased concentrations of anti-inflammatory N-acylethanolamines – namely palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and docosahexaenoylethanolamide (DHAEA) – while diminishing levels of oxidized arachidonic acid derivatives. KAM further suppressed cyclooxygenase-2 (COX-2) protein and selectively reduced the endocannabinoid 2-arachidonoylglycerol (2-AG), reflecting alterations in arachidonic acid metabolism. These molecular effects were accompanied by elevated peroxisome proliferator-activated receptor alpha (PPARα) and cannabinoid receptors CB1R and CB2R, supporting activation of anti-inflammatory pathways at both nuclear and membrane levels. No marked changes emerged in the temporal-occipital cortex. In plasma, DHAEA levels increased in parallel with cortical findings, whereas PEA and OEA elevations were restricted to shamoperated KAM-treated subjects, implying potential central redistribution during hypoperfusion/reperfusion stress. Collectively, these results indicate that KAM confers anti-inflammatory protection by both suppressing COX-2- mediated prostanoid production and enhancing PPARα-dependent lipid signaling. This dual mechanism underscores KAM’s promise as a dietary strategy to mitigate neuroinflammation following hypoperfusion– reperfusion injury
THERMAL CONDUCTIVITY OF MATERIALS WITH OXIDE-CERAMIC COATINGS, OBTAINED BY MICROARC OXIDATION
Year: 2025
Type: article
Language: en
Topic: Material Properties and Applications
Authors and affiliations:
raw_author_name: Aleksey Krivenkov
raw_author_name: Viktor Batrashov
raw_affiliation_strings: Penza State University
raw_author_name: Il'ya Kiselev
raw_affiliation_strings: Penzenskiy gosudarstvennyy universitet
raw_author_name: Anton Akimov
Evaluation of Bus Lane Implementation Expediency on Streets with Different Lane Numbers: Case Study
Year: 2025
Type: article
Language: en
Topic: Traffic control and management
Authors and affiliations:
raw_author_name: Fuad Dashdamirov
raw_affiliation_strings: Logistics and Transport Institute , Azerbaijan Technical University , Baku , Azerbaijan
raw_author_name: Turan Verdiyev
raw_affiliation_strings: Logistics and Transport Institute , Azerbaijan Technical University , Baku , Azerbaijan
Enhanced structural, morphological, optical, and electrical properties of Cu-doped SnO2 for advanced p–n junction diode applications
Year: 2025
Type: article
Language: en
Topic: ZnO doping and properties
Authors and affiliations:
raw_author_name: R. Marnadu
raw_affiliation_strings: Department of Condensed Matter Physics, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, SIMATS, Chennai, Tamil Nadu, 602105, India
raw_author_name: S. Sugarthi
raw_affiliation_strings: Department of Physics and Nanotechnology, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu, 603203, India
raw_author_name: K. S. Mohan
raw_affiliation_strings: Department of Physics, Nandha Engineering College, Erode, Tamil Nadu, 638052, India
raw_author_name: Farhat S. Khan
raw_affiliation_strings: College of Arts and Sciences, Dehran Aljunoub, King Khalid University, P.O. Box 62527, Abha, Saudi Arabia
raw_author_name: Mohd Taukeer Khan
raw_affiliation_strings: Department of Physics, Faculty of Science, Islamic University of Madinah, Madinah, Saudi Arabia
raw_author_name: Mohd. Shkir
raw_affiliation_strings: Department of Physics, College of Science, King Khalid University, P.O. Box 960, Abha, AlQura’a, 61421, Saudi Arabia
Smart Nano-Materials for Energy and Optoelectronic Devices Lab, Central Labs, King Khalid University, P.O. Box 960, Abha, AlQura’a, 61421, Saudi Arabia
raw_author_name: Vasudeva Reddy Minnam Reddy
raw_affiliation_strings: School of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea
raw_author_name: P. Parasuraman
raw_affiliation_strings: Department of Physics, Bannari Amman Institute of Technology, Sathyamangalam, Erode, Tamil Nadu, 638401, India
Exploring the Mediating Role of Teacher–Student Interaction in Technology-Enhanced Vocational Education: Evidence from a Structural Equation Modelling Study
Year: 2025
Type: article
Language: en
Topic: Educational Environments and Student Outcomes
Authors and affiliations:
raw_author_name: Titus Kurra
raw_affiliation_strings: Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Syarifuddin .
raw_affiliation_strings: Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Ervi Novitasari
raw_affiliation_strings: Agricultural Technology Education, Universitas Negeri Makassar, Makassar, South Sulawesi
Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Lativa Mursyida
raw_affiliation_strings: Electronic Engineering, Universitas Negeri Padang, Padang, West Sumatra
Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Khaidir Rahman
raw_affiliation_strings: Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Retyana Wahrini
raw_affiliation_strings: Electronic Engineering, State University of Makassar Faculty of Engineering, Makassar, South Sulawesi
Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
raw_author_name: Andry Tanggu Mara
raw_affiliation_strings: Technology and Vocational Education, Universitas Negeri Yogyakarta Program Pascasarjana, Yogyakarta, Special Region of Yogyakarta
Pass the prescription: improving antibiotic stewardship
Year: 2025
Type: letter
Language: en
Topic: Antibiotic Use and Resistance
Authors and affiliations:
raw_author_name: D. Sundararajan
raw_affiliation_strings: Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom. sdeepika@hotmail.co.uk
Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom
raw_author_name: S. Shivji
raw_affiliation_strings: Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom. sarika.shivji@nhs.net
Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom
raw_author_name: A. Parbhoo
raw_affiliation_strings: Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom. alan.parbhoo@ldh.nhs.uk
Department of Oral & Maxillofacial Surgery, Luton & Dunstable University Hospital, Bedfordshire Hospitals NHS Foundation Trust, Luton, United Kingdom
A new diagnostic frontier: the ‘EasyAge app' for cervical vertebral maturation staging
Year: 2025
Type: article
Language: en
Topic: Cervical and Thoracic Myelopathy
Authors and affiliations:
raw_author_name: Navaljeet Kaur Mann
raw_affiliation_strings: Consultant, Oral and Maxillofacial Surgery, Ludhiana, India. Navaljeetkaurmann@gmail.com
Consultant, Oral and Maxillofacial Surgery, Ludhiana, India
Raising awareness of oral cancer at the Royal Cornwall Hospital
Year: 2025
Type: article
Language: en
Topic: Dental Education, Practice, Research
Authors and affiliations:
raw_author_name: Alison Brown
raw_affiliation_strings: Dental Hygienist and Clinical Supervisor, Peninsula Dental School, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Dental Hygienist and Clinical Supervisor, Peninsula Dental School, University of Plymouth, Plymouth, UK
raw_author_name: Guy Lambourn
raw_affiliation_strings: Clinical Lead Truro DEF, Peninsula Dental School, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Clinical Lead Truro DEF, Peninsula Dental School, University of Plymouth, Plymouth, UK
raw_author_name: Ness Avery
raw_affiliation_strings: Clinical Lecturer in Dental Education, Peninsula Dental School, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Clinical Lecturer in Dental Education, Peninsula Dental School, University of Plymouth, Plymouth, UK
raw_author_name: Safiya Robinson
raw_affiliation_strings: Clinical Lecturer in Dental Education, Peninsula Dental School, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Clinical Lecturer in Dental Education, Peninsula Dental School, University of Plymouth, Plymouth, UK
raw_author_name: Tanya Lommerse
raw_affiliation_strings: Specialist in Oral Surgery, Royal Cornwall Hospital and Clinical Supervisor, Truro DEF, Peninsula Dental School, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Specialist in Oral Surgery, Royal Cornwall Hospital and Clinical Supervisor, Truro DEF, Peninsula Dental School, University of Plymouth, Plymouth, UK
raw_author_name: Casper Jonker
raw_affiliation_strings: Peninsula Dental School Year 4 Programme Lead, University of Plymouth, Plymouth, UK. bdj.news@springernature.com
Peninsula Dental School Year 4 Programme Lead, University of Plymouth, Plymouth, UK
AI, digital dentistry and patient equity
Year: 2025
Type: letter
Language: en
Topic: Artificial Intelligence in Healthcare and Education
Authors and affiliations:
raw_author_name: S. H. Ibrahim
raw_affiliation_strings: Centre of Comprehensive Care Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Selangor, Malaysia; Special Care Dentistry Unit, Department of Oral and Maxillofacial Surgery and Oral Diagnosis, Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan, Malaysia. hajaribrahim@iium.edu.my
Special Care Dentistry Unit, Department of Oral and Maxillofacial Surgery and Oral Diagnosis, Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan, Malaysia
Centre of Comprehensive Care Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Selangor, Malaysia
raw_author_name: A. F. Luai
raw_affiliation_strings: Dental Public Health Discipline, Department of Family Oral Health, Faculty of Dentistry, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia; Alliance for a Cavity-Free Future Malaysia Chapter (ACFF MC), Kuala Lumpur, Malaysia. dramirulfaiz@ukm.edu.my
Alliance for a Cavity-Free Future Malaysia Chapter (ACFF MC), Kuala Lumpur, Malaysia
Dental Public Health Discipline, Department of Family Oral Health, Faculty of Dentistry, Universiti Kebangsaan Malaysia (UKM), Kuala Lumpur, Malaysia
raw_author_name: M. S. Ahmad
raw_affiliation_strings: Centre of Comprehensive Care Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Selangor, Malaysia. massuryalis@gmail.com
Centre of Comprehensive Care Studies, Faculty of Dentistry, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, Selangor, Malaysia
Comparing Sulfur Sources in a No-Till Wheat–Soybean Cropping System
Year: 2025
Type: article
Language: en
Topic: Nitrogen and Sulfur Effects on Brassica
Authors and affiliations:
raw_author_name: Vanderson Modolon Duart
raw_affiliation_strings: Postgraduate Program in Agronomy, State University of Ponta Grossa, Ponta Grossa, Parana, Brazil
raw_author_name: Grazielle Schornobai
raw_affiliation_strings: Postgraduate Program in Agronomy, State University of Ponta Grossa, Ponta Grossa, Parana, Brazil
raw_author_name: Eduardo Fávero Caires
raw_affiliation_strings: Department of Soil Science and Agricultural Engineering, State University of Ponta Grossa, Ponta Grossa, Parana, Brazil
State University of Ponta Grossa, Av. Carlos Cavalcanti 4748, Ponta Grossa, 84030- 900, Parana, Brazil
Pratiques inconstitutionnelles françaises à la lumière de l’histoire
Year: 2025
Type: article
Language: en
Topic: Legal Systems and Institutions
Authors and affiliations:
raw_author_name: Marcel Morabito
raw_affiliation_strings: Sciences Po Paris
DICE / ILF-GERJC - Droits International, Comparé et Européen/ Institut Louis Favoreu - Groupe d 'études et de recherches sur la justice constitutionnelle [DICE - UMR 7318] (Institut Louis Favoreu - Groupe d'études et de recherches sur la justice constitutionnelle 
Espace Cassin, 3 Av Robert Schuman 13628 AIX EN PROVENCE CEDEX 1 - France)
Sciences Po - Sciences Po (27, rue Saint-Guillaume - 75337 Paris cedex 07 - France)
John Mankey Riggs 1810(?)-1885: the first specialist periodontist, the first to perform surgery under general anaesthesia and dentist to Mark Twain
Year: 2025
Type: article
Language: en
Topic: Dental Anxiety and Anesthesia Techniques
Authors and affiliations:
raw_author_name: David G. Hillam
raw_affiliation_strings: Retired Consultant in Restorative Dentistry (Periodontology), Stonehouse, United Kingdom. dg.hillam@gmail.com
Retired Consultant in Restorative Dentistry (Periodontology), Stonehouse, United Kingdom
Author Q&amp;A: Aseel Moqbel
Year: 2025
Type: article
Language: en
Topic: Diverse Scientific and Economic Studies
Authors and affiliations:
raw_author_name: Aseel Moqbel
raw_affiliation_strings: Near East University, Faculty of Dentistry, Department of Orthodontics, Mersin10, Turkey. aseel.moqbel@neu.edu.tr
Electrochemical corrosion behavior of Sn-58Bi-XNi solder alloy in 3.5 wt.% NaCl solution
Year: 2025
Type: article
Language: en
Topic: Electronic Packaging and Soldering Technologies
Authors and affiliations:
raw_author_name: Chong Fu
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: Wan Yi
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: DongYang Zhang
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: Dong Xiao
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: ZuXin Fan
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: RuiKang Xiao
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: MiaoMiao Liang
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
raw_author_name: Yan Hou
raw_affiliation_strings: School of Materials Science and Engineering, Xi’an Polytechnic University, Xi’an, 710048, China
From practice to publication: recognising all contributions
Year: 2025
Type: editorial
Language: en
Topic: Academic Writing and Publishing
Authors and affiliations:
raw_author_name: Wendy Thompson
raw_affiliation_strings: Division of Dentistry, University of Manchester, United Kingdom. bdjmanuscripts@nature.com
raw_author_name: Andrew Kirkcaldy
raw_affiliation_strings: Division of Dentistry, University of Manchester, United Kingdom. bdjmanuscripts@nature.com
raw_author_name: Matthew Byrne
raw_affiliation_strings: Division of Dentistry, University of Manchester, United Kingdom. bdjmanuscripts@nature.com
Psychopharmacology Treatment of Schizoaffective Disorder
Year: 2025
Type: article
Language: en
Topic: Electroconvulsive Therapy Studies
Authors and affiliations:
raw_author_name: David N. Osser
raw_affiliation_strings: Mental Health & Behavioral Sciences Service, VA Boston Healthcare System, Brockton, Massachusetts, USA,Harvard South Shore Psychiatry Training Program, Brockton, Massachusetts, USA