Targeting Tumor Microenvironment–Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer
Year: 2025
Type: article
Language: en
Topic: Prostate Cancer Treatment and Research
Authors and affiliations:
raw_author_name: Brian M. Shinder
raw_affiliation_strings: 1Department of Urology, Yale School of Medicine, New Haven, Connecticut
2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
Johns Hopkins University, Baltimore, MD, United States
raw_author_name: Young Sun Lee
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Ninghui Mao
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Nazifa Salsabeel
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
3Department of Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, New York
Icahn School of Medicine at Mount Sinai, New York, NY, United States
raw_author_name: Zeda Zhang
raw_affiliation_strings: 4Department of Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Harmanpreet Kaur
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Xiaoping Chen
raw_affiliation_strings: 5Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York City, New York
Memorial Sloan Kettering Cancer Center, New York, United States
raw_author_name: Qing Chang
raw_affiliation_strings: 5Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York City, New York
Memorial Sloan Kettering Cancer Center, New York, New York, United States
raw_author_name: Elisa de Stanchina
raw_affiliation_strings: 5Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York City, New York
Memorial Sloan Kettering Cancer Center, New York, United States
raw_author_name: Anuradha Gopalan
raw_affiliation_strings: 6Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Charles L. Sawyers
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
7Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States
raw_author_name: Brett S. Carver
raw_affiliation_strings: 2Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York
8Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York
9Division of Urology, Memorial Sloan Kettering Cancer Center, New York, New York
Memorial Sloan Kettering Cancer Center, New York, NY, United States