LabID-base/OpenAlex-Afillation huggingface dataset:
Vancomycin heteroresistance (hVISA) in MRSA links to treatment failure and supports a revised PAP-AUC threshold
Year: 2025
Type: article
Language: en
Topic: Antimicrobial Resistance in Staphylococcus
Authors and affiliations:
raw_author_name: Nikos Fatsis-Kavalopoulos
raw_affiliation_strings: Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
raw_author_name: Yong Kyun Kim
raw_affiliation_strings: Division of Infectious Diseases, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea
Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. yskim@amc.seoul.kr
raw_author_name: Yong Pil Chong
raw_affiliation_strings: Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
raw_author_name: Seongman Bae
raw_affiliation_strings: Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
raw_author_name: So Yun Lim
raw_affiliation_strings: Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
raw_author_name: Yang Soo Kim
raw_affiliation_strings: Division of Infectious Diseases, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea
Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. yskim@amc.seoul.kr
Division of Infectious Diseases, Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
raw_author_name: Dan I. Andersson
raw_affiliation_strings: Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden. Dan.Andersson@imbim.uu.se
Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden
Tuning electrical performance of Sc2O3/SiO2/Si MOS capacitors through interface and thermal processing
Year: 2025
Type: article
Language: en
Topic: Semiconductor materials and devices
Authors and affiliations:
raw_author_name: Muhsin Uğur Doğan
raw_affiliation_strings: Department of Electronic and Automation, Bolu Abant Izzet Baysal University, Bolu, Turkey
The correlation between the systemic immune-inflammatory index and the risk of major adverse cardiovascular events after transcatheter aortic valve replacement: a retrospective cohort study
Year: 2025
Type: article
Language: en
Topic: Inflammatory Biomarkers in Disease Prognosis
Authors and affiliations:
raw_author_name: Rui Han
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Zhenwei Wang
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, China
raw_author_name: Hailong Zhang
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Yujia Wu
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Wanqian Pan
raw_affiliation_strings: Department of Cardiovascular Medicine, The First Affiliated Hospital, Hainan Medical University, Haikou, 570100, China
raw_author_name: Hang Li
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Xiaodong Qian
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Haifeng Xu
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Tingbo Jiang
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China. jtbsdfyy@163.com
Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China
raw_author_name: Weixiang Chen
raw_affiliation_strings: Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, 215031, China. chenweixiang@suda.edu.cn
Activities undertaken by Indigenous Australians as “caring for Country”: A systematic review
Year: 2025
Type: review
Language: en
Topic: Indigenous Health, Education, and Rights
Authors and affiliations:
raw_author_name: Geoffrey R. Browne
raw_affiliation_strings: Melbourne School of Design, Faculty of Architecture, Building and Planning, University of Melbourne, Parkville, VIC, 3010, Australia. Geoffrey.browne@unimelb.edu.au
raw_author_name: Kate Haughey
raw_affiliation_strings: LatStudios, Level 2, 358 Lonsdale Street, Melbourne, VIC, 3000, Australia
Syphilitic oral ulceration: easy to confuse with similar
Year: 2025
Type: article
Language: en
Topic: Syphilis Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Paul Hellyer
raw_affiliation_strings: Retired GDP/Clinical Teacher, Bexhill-on-Sea, East Sussex, United Kingdom. bdjmanuscripts@nature.com
Retired GDP/Clinical Teacher, Bexhill-on-Sea, East Sussex, United Kingdom
THE EFFECT OF ANTIBIOTIC-INDUCED DYSBIOSIS ON PERIPHERAL NERVE REPAIR
Year: 2025
Type: article
Language: en
Topic: Gut microbiota and health
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Human gut microbiota is the dynamic and complex population of microorganisms (bacteria, fungi, protozoa and viruses), which contributes to tissue homeostasis through a series of physiological functions. The gut microbiota influences not only the gastrointestinal tract, but also a growing list of other organs, impacting on function such as barrier integrity, metabolism, hematopoiesis and inflammation, leading to its consideration as a ‘vital organ’. Recently, our laboratory identified a connection between the gut microbiota and the peripheral nervous system (PNS). To study the impact of microbiota composition on peripheral nerve regeneration, we administered a cocktail of antibiotics (vancomycin 0.25 mg/mL, ampicillin 0.5 mg/mL, metronidazole 0.5 mg/mL) to mice via drinking water. Animals were divided into four groups: Group 1 (Treated with antibiotics before and after the surgery), Group 2 (Treated with antibiotics before the surgery), Group 3 (Treated with antibiotics after the surgery) and Group 4 (Not treated with antibiotics). Mice were subjected to peripheral nerve injury (transection or crush) and, after 2, 7 or 28 days different tissues/organs were harvested for the analysis: median and ulnar nerve, flexor digitorum superficialis and flexor digitorum profundus, spleen, lymphnodes, serum, fecal pellet, DRGs, and forepaw. To assess functional recovery, we performed the grasping test. Antibiotic treatment did not cause weight loss or evident behavioral alterations. Microbiota analysis revealed distinct patterns across groups/treatments and timepoints. Overall, antibiotic treatment induced dysbiosis, with the extent and nature of the disruption varying according to treatment duration. The rescue group (treated only before surgery) demonstrated partial recovery of the microbiota, particularly at later timepoints. The grasping test revealed that mice treated 10 days before median nerve injury showed reduced strength in the injured forelimb compared to untreated animals until day 10 post-injury. This difference progressively diminished, with similar performance among groups by day 28. Additional analyses are ongoing. Our findings indicate that microbiota depletion leads to functional alterations in the PNS. Further analyses are ongoing to elucidate mechanisms underlying these effects
Correction: Fishing for wages: remuneration gaps and attractiveness of the EU fisheries sector
Year: 2025
Type: article
Language: en
Topic: Coastal and Marine Management
Authors and affiliations:
raw_author_name: Jordi Guillen
raw_affiliation_strings: European Commission, Joint Research Centre (JRC), Ispra, Italy
raw_author_name: Antonio Borriello
raw_affiliation_strings: European Commission, Joint Research Centre (JRC), Ispra, Italy
raw_author_name: Natacha Carvalho
raw_affiliation_strings: European Environment Agency (EEA), Copenhagen, Denmark
raw_author_name: Simone Quatrini
raw_affiliation_strings: European Commission, Joint Research Centre (JRC), Ispra, Italy
Cytometric Analysis of CD3 + CD4 + T Populations and Activation and Regulation Status of Naïve and Memory CD4 + CD45RA T Cells in Immunocompetent Patients with Neurocryptococcosis
Year: 2025
Type: article
Language: en
Topic: Fungal Infections and Studies
Authors and affiliations:
raw_author_name: Isabel Feitosa Maciel
raw_affiliation_strings: Dermatology and Immunodeficiency Research Laboratory (LIM56), Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo., São Paulo-SP, Brazil. biomed.isabelmaciel@alumni.usp.br
Dermatology and Immunodeficiency Research Laboratory (LIM56), Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo., São Paulo-SP, Brazil
raw_author_name: Juliana Ruiz
raw_affiliation_strings: Dermatology and Immunodeficiency Research Laboratory (LIM56), Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo., São Paulo-SP, Brazil
raw_author_name: Renata Buccheri de Oliveira
raw_affiliation_strings: Vitalant Research Institute, University of California, San Francisco, USA
raw_author_name: Paula Ordonhez Rigato
raw_affiliation_strings: Immunobiology and Biomarkers Laboratory, Immunology Center, Adolfo Lutz Institute, São Paulo-SP, Brazil
raw_author_name: Victor Angelo Folgosi
raw_affiliation_strings: Dermatology and Immunodeficiency Research Laboratory (LIM56), Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo., São Paulo-SP, Brazil
raw_author_name: Roseli Santos de Freitas-Xavier
raw_affiliation_strings: Microbiology Laboratory, Central Laboratory Division and Laboratory Pathology Laboratory (LIM 03Department of PathologyFaculdade de Medicina, Hospital das Clinicas, Universidade de São Paulo., São Paulo-SP, Brazil
raw_author_name: Dewton de Moraes Vasconcelos
raw_affiliation_strings: Dermatology and Immunodeficiency Research Laboratory (LIM56), Department of Dermatology, Hospital das Clínicas, School of Medicine, University of São Paulo., São Paulo-SP, Brazil
The association of nationwide trainee doctor mass resignations in South Korea with hospital utilization, expenditure, and patient outcomes
Year: 2025
Type: article
Language: en
Topic: Hospital Admissions and Outcomes
Authors and affiliations:
raw_author_name: Seonghoon Kim
raw_affiliation_strings: Singapore Management University, Singapore, Singapore
raw_author_name: SangNam Ahn
raw_affiliation_strings: Saint Louis University, St. Louis, MO, United States
raw_author_name: Kanghyock Koh
raw_affiliation_strings: Korea University, Seongbuk-gu, Republic of Korea
raw_author_name: Donghyoun Lee
raw_affiliation_strings: Jeju National University Hospital, Jeju National University College of Medicine, Jeju-si, Republic of Korea
Distinct patterns in neuromuscular adaptation to repeated perturbations in chronic ankle instability
Year: 2025
Type: article
Language: en
Topic: Foot and Ankle Surgery
Authors and affiliations:
raw_author_name: Xiaohan Xu
raw_affiliation_strings: Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK. xx274@exeter.ac.uk
Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK
raw_author_name: Joanna Bowtell
raw_affiliation_strings: Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK
raw_author_name: William R. Young
raw_affiliation_strings: Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK
raw_author_name: Daniel T. P. Fong
raw_affiliation_strings: National Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, LE11 3TT, UK
raw_author_name: Genevieve K. R. Williams
raw_affiliation_strings: Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK. g.k.r.williams@exeter.ac.uk
Public Health and Sports Sciences Department, University of Exeter, Exeter, EX1 2LU, UK
Mitigating cyberbullying’s impact on children’s well-being: The roles of digital literacy and cognitive emotion regulation
Year: 2025
Type: article
Language: en
Topic: Bullying, Victimization, and Aggression
Authors and affiliations:
raw_author_name: Qianru Liang
raw_affiliation_strings: Guangdong Institute of Smart Education, Jinan University, Guangzhou, China
raw_author_name: Sisi Tao
raw_affiliation_strings: Department of Early Childhood Education, Education University of Hong Kong, Hong Kong SAR, China
raw_author_name: Qianqian Pan
raw_affiliation_strings: Centre for Research in Pedagogy and Practice (CRPP), Nanyang Technological University, Singapore, Singapore
raw_author_name: Min Lan
raw_affiliation_strings: Zhejiang Key Laboratory of Intelligent Education Technology and Application, Zhejiang Normal University, Jinhua, China
raw_author_name: Zemin Guo
raw_affiliation_strings: Faculty of Education, University of Hong Kong, Hong Kong SAR, China
raw_author_name: Wenhui Li
raw_affiliation_strings: Teaching and Learning Centre, Lingnan University, Hong Kong SAR, China
raw_author_name: Yimeng Li
raw_affiliation_strings: Faculty of Education, University of Hong Kong, Hong Kong SAR, China
raw_author_name: Cheng Yong Tan
raw_affiliation_strings: Faculty of Education, University of Hong Kong, Hong Kong SAR, China
raw_author_name: Nancy Law
raw_affiliation_strings: Faculty of Education, University of Hong Kong, Hong Kong SAR, China
Spin-dependent transport through graphene-based quantum antidot nanoribbon in the presence of Rashba coupling
Year: 2025
Type: article
Language: en
Topic: Graphene research and applications
Authors and affiliations:
raw_author_name: A. Naifar
raw_affiliation_strings: Laboratory of Chemistry, Materials and Modelling (LR24ES02), Department of Physics, University of Kairouan, Kairouan, Tunisia
Preparatory Institute for Engineering Studies of Kairouan, (I.P.E.I.K), University of Kairouan, Kairouan, Tunisia
raw_author_name: A. Phirouznia
raw_affiliation_strings: Azarbaijan Shahid Madani University, Tabriz, 53714-161, Iran
raw_author_name: K. Hasanirokh
raw_affiliation_strings: Azarbaijan Shahid Madani University, Tabriz, 53714-161, Iran
THE NEUROPROTECTIVE PEPTIDES &lt;i&gt;PACAP&lt;/i&gt; AND &lt;i&gt;ADNP&lt;/i&gt; RESCUE CEREBELLAR GRANULE CELLS FROM APOPTOSIS
Year: 2025
Type: article
Language: en
Topic: Nuclear Receptors and Signaling
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Neuronal fate is determined by signals that promote either survival or apoptotic death. These signals are essential for the proper development of the central nervous system and the maintenance of homeostasis in adulthood
however, their dysregulation can contribute to the onset of neurological disorders. Through genomic screening and a reverse engineering approach, we previously characterized the transcriptional program regulating apoptosis and survival in cerebellar granule cells (CGCs) deprived of neurotrophic factors. Among the genes analyzed, we identified two transcription factors – Homeobox D9 (Hoxd9) and Nuclear Receptor 4A1 (Nr4a1) – as potential master regulators of the apoptotic process in CGCs cultured under serum deprivation and low potassium conditions (5 mM KCl). In the present study, we investigated the neuroprotective effects of the peptides PACAP and ADNP to assess whether they can prevent neuronal death by modulating the expression of these transcription factors. Using a continuous CGC cell line, we defined the temporal window of neuroprotection for both peptides and evaluated their impact on Hoxd9 and Nr4a1 expression levels. Our findings suggest that Hoxd9 and Nr4a1 may play a pivotal role in the genetic program underlying neuronal survival and represent potential targets for neuroprotective strategies. This study was supported by Unione Europea-Next Generation EU PNRR per Mac2I1.1 (grant number:2022RTBHJ) CUPE53D23015490001
CHANGE IN AQUAPORIN-4 EXPRESSION AND LOCALIZATION DURING AMYOTROPHIC LATERAL SCLEROSIS AND SPINAL MUSCULAR ATROPHY PROGRESSION
Year: 2025
Type: article
Language: en
Topic: Cerebrospinal fluid and hydrocephalus
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: The glymphatic system is a glial-dependent perivascular network responsible for clearing waste and neurotoxic substances from the central nervous system. Aquaporin-4 (AQP4) water channels, expressed on the astrocyte endfeet and localized around blood vessels, are key components of this system. Dysfunction of the glymphatic pathway has been associated with several neurodegenerative diseases, including Alzheimer’s disease and Amyotrophic Lateral Sclerosis (ALS). Our purpose was to evaluate if the alterations in AQP4 expression may also contribute to neurodegeneration in ALS and Spinal Muscular Atrophy (SMA), two different motor neuron diseases. We investigated AQP4 expression in the ventral horns of spinal cord in delta7SMN and SOD1G93A mice, respectively SMA and ALS models. Three time points were selected to represent the presymptomatic, early symptomatic, and late disease stages. The lumbar spinal cord was collected, sectioned at 40 μm, and processed for immunofluorescence analysis using antibodies against AQP4, GFAP (astroglial marker) and ChAT (motor neuron marker). Images were acquired with a Zeiss Apotome microscope and analyzed with ImageJ. We observed a significant increase in AQP4 expression in SOD1G93A mice at both early and late disease stages compared to healthy controls: specifically, during these stages, AQP4 levels in the peri-motoneuronal region increased by 89.8% and 45.6%, respectively, in ALS mice relative to controls. In addition, an increasing trend in AQP4 expression was detected between the presymptomatic and early disease stages. Conversely, AQP4 levels decreased at the late stage, possibly due to neurodegeneration. Comparable expression patterns were observed in SMA mice, in which the increase between the presymptomatic and early stages reached approximately 36%. Our study highlights a potential contribution of the glymphatic system in the pathogenesis of motor neuron diseases and suggests AQP4 as a potential therapeutic target to delay neurodegeneration
An annotated clinical image dataset for AI classification of malignant and potentially malignant oral lesions
Year: 2025
Type: article
Language: en
Topic: Dental Radiography and Imaging
Authors and affiliations:
raw_author_name: Noran Ayman
raw_affiliation_strings: Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt. noran.ayman@dentistry.cu.edu.eg
Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt
raw_author_name: Fat´heya M. Zahran
raw_affiliation_strings: Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt
raw_author_name: Yomna Safaa El-Din
raw_affiliation_strings: Computer and Systems Engineering Department, Ain Shams University, Cairo, Egypt
raw_author_name: Noha Adel Azab
raw_affiliation_strings: Department of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Cairo, Egypt
GAIT CHARACTERIZATION IN A MOUSE MODEL OF CHRONIC MILD STRESS- AND 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE-INDUCED NEUROINFLAMMATION
Year: 2025
Type: article
Language: en
Topic: Parkinson's Disease Mechanisms and Treatments
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Chronic mild stress (CMS) is an etiological risk factor for neuroinflammation that, in turn, is involved in the pathogenesis and progression of Parkinson’s disease (PD). To study the relationship between CMS, neuroinflammation and PD, we set up an in vivo model in which mice were subjected to CMS and, at the end of treatment, received 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) that causes the selective degeneration of the substantia nigra dopaminergic neurons, that is the main pathological feature of PD. In patients, disturbances in gait are symptomatic of PD. In mice, the administration of MPTP results in PD symptoms, including gait alteration. Several studies in mouse models of PD have characterized gait by estimating stride parameters by painting animals’ paws. Therefore, to compare the effects CMS and MPTP on mice gait, from the analysis footprint patterns four step parameters were measured: stride length, hind-base width, front-base width and overlap between forepaw and hindpaw placement. Control and stressed mice exhibited comparable stride lengths for both forepaws and hindpaws. By contrast, MPTP-treated mice displayed a significantly shorter stride length compared with control mice (p<0.05), as well as MPTP-treated stressed mice compared to the ones subjected only to CMS (p<0.05). The frontbase width did not differ significantly in mice from all experimental conditions
also hindbase width of MPTP-treated stressed mice resulted significantly higher compared to the one of mice subjected only to CMS (p<0.05). Stressed mice displayed reduced hindbase width compared to control one. The front/hind footprint overlap provides an indication of the accuracy of foot placement and of the uniformity of step alternation: surprisingly, MPTP-treated mice displayed a footprint overlap similar to control one whereas, as expected, overlap in MPTPtreated stressed mice resulted significantly lower compared to the ones subjected only to CMS (p<0.05). Although stressed mice displayed better step overlap compared to control one, the variability of the distances measured resulted higher. Overall, these data suggest that MPTP induced in both unstressed and stressed mice a significative gait alteration compared to respective controls, while the effects of CMS on motor behaviour were limited to the alteration of the uniformity of step alternation
in contrast, the hindbase width of MPTP-treated mice was broader than that shown by controls (p<0.05)