LabID-base/OpenAlex-Afillation huggingface dataset:
MORPHOLOGICAL AND TRANSCRIPTOMIC ANALYSES HIGHLIGHT DIFFERENTIAL REGENERATION KINETICS IN IMMEDIATE &lt;i&gt;VERSUS&lt;/i&gt; DELAYED NERVE REPAIR
Year: 2025
Type: article
Language: en
Topic: Nerve injury and regeneration
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Peripheral nerve injuries represent a significant clinical challenge due to their limited regenerative capacity. Although immediate repair is ideal, delayed intervention is often unavoidable. Understanding the mechanisms underlying both conditions is essential for optimizing functional recovery. Thus, this study aimed to uncover key pathways in nerve regeneration through the first transcriptomic analysis of regenerating nerves within a conduit, also comparing immediate and delayed nerve repair over time in a rat model. Immediately after injury, or following a delay of three months, microsurgical intervention with a chitosan tube was performed to repair an 8-mm median nerve gap, and regenerated nerves inside the conduit were collected at 14- and 21-days for morphometric analysis, and at 7-, 14-, and 21-days post-repair for RNA sequencing. Morphometric analysis based on absolute values showed a significant reduction in Schwann cell and axonal areas at 14-days, along with a decreased number of blood vessels and an overall smaller section area at 21-days in the delayed group. However, when normalized to the total section area to assess the relative proportions occupied by Schwann cells, axons, and vessels, no significant differences were observed between immediate and delayed groups at 21-days. To correlate morphometric data with transcriptomic profiles, RNA sequencing was conducted. Approximately 25,000 genes were differentially expressed in regenerating nerves compared to healthy controls, mainly related to inflammatory response, phagocytosis, cell signalling, and response to lipoprotein particles. Only 137 genes differed between delayed and immediate repair. Gene ontology analysis showed that the most enriched pathways were involved in angiogenesis, especially at 7-days, in accordance with the higher density of vessel area observed at 14-days. Overall, the comparison between the experimental groups indicated that immediate repair initiated a more rapid regenerative response, while delayed repair followed a slower, but ultimately convergent, trajectory highlighting that regeneration is postponed and partially impaired. Indeed, it is noteworthy that the nerve calibre was hindered in the delayed compared to the immediate repair. These findings underscore the importance of early intervention, but also suggest that, over time, delayed repair might achieve similar regenerative outcomes, especially if novel therapies will be developed to further enhance recovery
Feeding management practices and forage utilization in smallholder goat farming in Oransbari District, Papua Barat
Year: 2025
Type: article
Language: id
Topic: Livestock Farming and Management
Authors and affiliations:
raw_author_name: Ribka H. Sellau
raw_affiliation_strings: Universitas Papua, Manokwari, Indonesia
raw_author_name: Evi W Saragih
raw_affiliation_strings: Universitas Papua, Manokwari, Indonesia
raw_author_name: Marlyn N. Lekitoo
raw_affiliation_strings: Universitas Papua, Manokwari, Indonesia
REDUCTION OF TRAFFIC DELAYS IN SPEED CONTROL AT REGULATED INTERSECTIONS
Year: 2025
Type: article
Language: en
Topic: Transportation Systems and Logistics
Authors and affiliations:
raw_author_name: Olga Fadina
raw_affiliation_strings: South Ural State University
raw_author_name: Vladimir Shepelyov
raw_affiliation_strings: South Ural State University
raw_author_name: Evgeny Akhmadeev
raw_affiliation_strings: South Ural State University
Problems of territorial planning and land management at the present stage and ways to solve them
Year: 2025
Type: article
Language: en
Topic: Agricultural Development and Policies
Authors and affiliations:
raw_author_name: Yury Tsypkin
raw_affiliation_strings: State University of Land Use Planning
raw_author_name: Sergey Korostelev
raw_affiliation_strings: State University of Land Use Planning
raw_author_name: Salimzyan Sharipov
raw_affiliation_strings: Kazan State Agrarian University
Особливості емоційно-вольової саморегуляції фахівців екстреного реагування в умовах воєнного стану
Year: 2025
Type: article
Topic: Military Technology and Strategies
Authors and affiliations:
raw_author_name: Ілона Руденко
raw_affiliation_strings: National University of Civil Defense of Ukraine
raw_author_name: Людмила Мохнар
raw_affiliation_strings: National University of Civil Defense of Ukraine
raw_author_name: Ольга Жогло
raw_affiliation_strings: National University of Civil Defense of Ukraine
CONNEXIN 43 HEMICHANNELS CAN DRIVE THE GLIOBLASTOMA SPREADING
Year: 2025
Type: article
Language: en
Topic: Connexins and lens biology
Authors and affiliations:
raw_author_name: Share
raw_affiliation_strings: Glioblastoma (GBM) is the most common and aggressive primary tumor of the central nervous system (CNS) among high-grade gliomas (HGG). Patients with GBM often have a poor prognosis. Glioblastoma cells have a remarkable ability to infiltrate the CNS and migrate long distances from the tumor core, making complete surgical resection impossible. GBM infiltration relies on electrical and molecular connections with nervous tissue. Among molecular interactions, connexin 43 (Cx43) appears to be a marker for HGG in mouse models. Cx43 is a multifunctional protein, and is found on the plasma membranes of glial cells – particularly astrocytes – in the form of gap junctions or hemichannels, ensuring cell-to-cell or cell-to-extracellular space communication, respectively. Cx43 can be expressed by transformed astrocytes, i.e., GBM cells. Its abnormal expression can alter the electrical state of the system, resulting in epileptic events. To study the dynamics of GBM spread in humans, we characterized tumor and peritumoral tissue from glioma patients. Using confocal microscopy and functional assays, we assessed the state of the neuroglial network in fresh brain sections. Electrical activity, Cx43 density, and glial reactivity were correlated with the degree of tumor infiltration. In parallel, primary human glioblastoma cells were labeled by lentiviral transduction and injected into organotypic tissue sections from the same patients. The glioblastoma cells were monitored until day seven in culture by time-lapse microscopy to follow tumor progression and their response to Gap19, a selective blocker of Cx43 hemichannels. Tumor tissue has a different architecture than peritumoral tissue, which is reflected in specific electrical and morphological profiles. In peritumoral tissue, implanted GBM cells spread into the neuroglial network, and blockade of Cx43 hemichannels results in tissue remodeling and GBM cell polarization, which may correspond to a migratory pattern. This study reveals that tumor progression is not an isolated phenomenon but it is driven by interactions with the surrounding environment in living brain tissue. In particular, Cx43 hemichannels emerge as key players in tumor spread and recurrence, revealing a more complex dynamic than expected. This finding challenges the traditional idea of GBM as an entity external to the brain, especially considering the rarity of its metastases
Anterior Cruciate Ligament Bundles Elongation Patterns During Fast Running and Single-Leg Drop Landing: An In Vivo Biplane Radiography Study
Year: 2025
Type: article
Language: en
Topic: Knee injuries and reconstruction techniques
Authors and affiliations:
raw_author_name: Kohei Kamada
raw_affiliation_strings: Biodynamics Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
raw_author_name: Tom Gale
raw_affiliation_strings: Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
raw_author_name: Koji Nukuto
raw_affiliation_strings: Biodynamics Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan
Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
raw_author_name: Volker Musahl
raw_affiliation_strings: Department of Orthopedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
raw_author_name: William Anderst
raw_affiliation_strings: Biodynamics Laboratory, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Identification types and nutritional composition of traditional pig feed in rural areas of Timor Island and its influence on production efficiency
Year: 2025
Type: article
Language: id
Topic: Livestock Farming and Management
Authors and affiliations:
raw_author_name: Ni N. Suryani
raw_affiliation_strings: Universitas Nusa Cendana, Kupang, Indonesia
raw_author_name: Fredeicus D. Samba
raw_affiliation_strings: Universitas Nusa Cendana, Kupang, Indonesia
raw_author_name: David A. Nguru
raw_affiliation_strings: Universitas Nusa Cendana, Kupang, Indonesia
raw_author_name: I. K. Yoga Kertiyasa
raw_affiliation_strings: Universitas Nusa Cendana, Kupang, Indonesia
raw_author_name: Asri A. Widu
raw_affiliation_strings: Universitas Nusa Cendana, Kupang, Indonesia
Periodontitis and incident cognitive decline and dementia: A 15-year prospective cohort study of older men residing in Northern Ireland
Year: 2025
Type: article
Language: en
Topic: Oral microbiology and periodontitis research
Authors and affiliations:
raw_author_name: Dominic N Farsi
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
Department of Nutritional Sciences, King's College London, London, UK
raw_author_name: Rena Abadalkareem
raw_affiliation_strings: School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
raw_author_name: Gerry J Linden
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
raw_author_name: Gareth J McKay
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
raw_author_name: Claire T McEvoy
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
raw_author_name: Michael McAlinden
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
Northern Ireland Clinical Research Network, Belfast Health and Social Care Trust, Belfast, UK
raw_author_name: Lewis Winning
raw_affiliation_strings: Dublin Dental University Hospital, Trinity College Dublin, Dublin, Ireland
raw_author_name: Michael Hurley
raw_affiliation_strings: School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
raw_author_name: Jo Kelly
raw_affiliation_strings: School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
raw_author_name: Peter A Passmore
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
raw_author_name: Clive Holmes
raw_affiliation_strings: School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
raw_author_name: Chris C Patterson
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
raw_author_name: Jessica L Teeling
raw_affiliation_strings: School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK
raw_author_name: Bernadette McGuinness
raw_affiliation_strings: Centre for Public Health, School of Medicine Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK
Optical properties of CdPbSe thin films: effects of deposition process and alloy composition
Year: 2025
Type: article
Language: en
Topic: Quantum Dots Synthesis And Properties
Authors and affiliations:
raw_author_name: Hamidreza Hatami
raw_affiliation_strings: Department of Physics, Faculty of Science, Malayer University, Malayer, Iran
raw_author_name: Nader Ghobadi
raw_affiliation_strings: Department of Physics, Faculty of Science, Malayer University, Malayer, Iran
raw_author_name: Dariush Mehrparvar
raw_affiliation_strings: Department of Physics, Faculty of Science, Malayer University, Malayer, Iran
A case report on post radiotherapy chylous ascites treated with “fasting + octreotide”
Year: 2025
Type: article
Language: en
Topic: Lymphatic Disorders and Treatments
Authors and affiliations:
raw_author_name: Jing-jing Wang
raw_affiliation_strings: Department of Oncology, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China
Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, China
raw_author_name: Lei Xie
raw_affiliation_strings: Department of Oncology, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China
raw_author_name: Xing-yu Chen
raw_affiliation_strings: Department of General Surgery, Taizhou Fourth People’s Hospital, Taizhou, China
Department of General Surgery, Taizhou Fourth People's Hospital, Taizhou, China
raw_author_name: Xiang Wang
raw_affiliation_strings: Department of Oncology, Taizhou Hospital of Traditional Chinese Medicine, Taizhou, China
SYNTHESIS OF CONTACTLESS DRIVES OF MACHINE TOOLS AND STUDY OF THEIR PARAMETERS AND CHARACTERISTICS
Year: 2025
Type: article
Language: en
Topic: Advanced Theoretical and Applied Studies in Material Sciences and Geometry
Authors and affiliations:
raw_author_name: Vladimir Breshev
raw_affiliation_strings: Lugansk Vladimir Dahl State University
raw_author_name: Yulia Dolzhenko
raw_affiliation_strings: Lugansk Vladimir Dahl State University
Citrus waste hydrochar performance as soil amendment in constructed wetlands for the treatment of wastewater from the sugarcane industry
Year: 2025
Type: article
Topic: Constructed Wetlands for Wastewater Treatment
Authors and affiliations:
raw_author_name: Ofelia Landeta-Escamilla
raw_affiliation_strings: Tecnológico Nacional de México, División de Estudios de Posgrado e Investigación
raw_author_name: Oscar O. Sandoval-Gonzalez
raw_affiliation_strings: Tecnológico Nacional de México, División de Estudios de Posgrado e In-vestigación
raw_author_name: Alejandro Alvarado-Lassman
raw_affiliation_strings: Tecnológico Nacional de México, División de Estudios de Posgrado e Investigación
raw_author_name: Norma A. Vallejo-Cantu
raw_affiliation_strings: Tecnológico Nacional de México, División de Estudios de Posgrado e In-vestigación
raw_author_name: Arely Gonzalez-Serrano
raw_affiliation_strings: Tecnológico Nacional de México, División de Estudios de Posgrado e Investigación
Health economics evidence for food system policy: a systematic review of reviews
Year: 2025
Type: article
Language: en
Topic: Global Public Health Policies and Epidemiology
Authors and affiliations:
raw_author_name: Lin Fu
raw_affiliation_strings: Centre for Economics of Obesity, School of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom
raw_author_name: Irina Pokhilenko
raw_affiliation_strings: Centre for Economics of Obesity, School of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom
raw_author_name: Thijs van Rens
raw_affiliation_strings: Department of Economics, University of Warwick, Coventry, United Kingdom
raw_author_name: Richard Smith
raw_affiliation_strings: Department of Public Health and Sport Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom
raw_author_name: Emma Frew
raw_affiliation_strings: Centre for Economics of Obesity, School of Applied Health Sciences, College of Medicine and Health, University of Birmingham, Birmingham, United Kingdom
A novel sensor-based real-time tracking game for assessing ankle proprioceptive effects on sensorimotor performance
Year: 2025
Type: article
Language: en
Topic: Balance, Gait, and Falls Prevention
Authors and affiliations:
raw_author_name: Monica Hruzd
raw_affiliation_strings: Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers Health, Rutgers University, 65 Bergen St. Room 166, Newark, NJ, 07107, USA
raw_author_name: Rylie Watson
raw_affiliation_strings: Department of Biomedical Engineering, University of Arizona, Tucson, AZ, USA
raw_author_name: Mohammad Hosseinalizadeh
raw_affiliation_strings: Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers Health, Rutgers University, 65 Bergen St. Room 166, Newark, NJ, 07107, USA
raw_author_name: Kubra Akbas
raw_affiliation_strings: Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers Health, Rutgers University, 65 Bergen St. Room 166, Newark, NJ, 07107, USA
raw_author_name: Nima Toosizadeh
raw_affiliation_strings: Brain Health Institute, Rutgers University, New Brunswick, NJ, USA. nima.toosizadeh@rutgers.edu
Department of Neurology, Rutgers Health, Rutgers University, Newark, NJ, USA. nima.toosizadeh@rutgers.edu
Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers Health, Rutgers University, 65 Bergen St. Room 166, Newark, NJ, 07107, USA. nima.toosizadeh@rutgers.edu
Department of Rehabilitation and Movement Sciences, School of Health Professions, Rutgers Health, Rutgers University, 65 Bergen St. Room 166, Newark, NJ, 07107, USA
Intestinal Behçet’s disease presenting with intestinal obstruction misdiagnosed as Crohn’s disease: a case report
Year: 2025
Type: article
Language: en
Topic: Ocular Diseases and Behçet’s Syndrome
Authors and affiliations:
raw_author_name: Jian Song
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China
raw_author_name: Liu-Hai Zeng
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China
raw_author_name: Wen-Yao Lv
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China
raw_author_name: Cheng-Hao Gu
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China
raw_author_name: Wei Lin
raw_affiliation_strings: Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China. 18757455613@163.com
Department of Gastrointestinal Surgery, Xiangshan First People's Hospital Medical and Health Group, Xiangshan, 315700, Zhejiang Province, PR China
Efficacy, safety, and patient-centered outcomes of needle-free injectors versus insulin pens in diabetes management: a comprehensive meta-analysis
Year: 2025
Type: review
Language: en
Topic: Diabetes Management and Research
Authors and affiliations:
raw_author_name: Jing Wang
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Xinhao Chen
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Zhili Ge
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Yingran Xia
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Zixiang Tang
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Zehao Sun
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Lijing Jiao
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Jing Zhou
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Lihui Zhang
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
raw_author_name: Zhansheng Zhao
raw_affiliation_strings: The Second Hospital of Hebei Medical University
The Second Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China
Spatial Approach for the Assessment of Public Transit Node Accessibility in Urban Areas of Developing Countries: Evidence from Addis Ababa, Ethiopia
Year: 2025
Type: article
Language: en
Topic: Urban Transport and Accessibility
Authors and affiliations:
raw_author_name: Eskindir Ayele Atumo
raw_affiliation_strings: School of Civil Engineering and Architecture, Dire Dawa University, Dire Dawa, Ethiopia
Electronics in Agriculture: Importance, Innovations, and Challenges for Smart Farming
Year: 2025
Type: article
Topic: Smart Agriculture and AI
Authors and affiliations:
raw_author_name: F. Javier Castillo-Romero
raw_affiliation_strings: Tecnológico Nacional de México/I.T. Orizaba
raw_author_name: Albino Martínez.-Sibaja
raw_affiliation_strings: Tecnológico Nacional de México/I.T. Orizaba
raw_author_name: H. Yahaira Hernández-Acosta
raw_affiliation_strings: Division de Ingeniería Mecatrónica y Centro de Innovación y emprendi-miento científico y tecnológico, Universidad Politécnica del Valle de Mé-xico
raw_author_name: Vijay Kumar-Shankar
raw_affiliation_strings: Nitte Meenakshi Institute of Technology. Department of Mechanical En-gineering
raw_author_name: J.J. Agustin Flores-Cuautle
raw_affiliation_strings: Secihti/Tecnológico Nacional de México/I.T