DISCO-seq: 3D single-cell transcriptomics of intact biological systems
Year: 2025
Type: preprint
Topic: Single-cell and spatial transcriptomics
Authors and affiliations:
raw_author_name: Harsharan Singh Bhatia
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Laurent H.A. Simons
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Louis B. Kuemmerle
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Cristin McCabe
raw_affiliation_strings: Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA;
raw_author_name: Sophie Jansen
raw_affiliation_strings: Department of Biosystems Science and Engineering, ETH Zuerich, Basel, Switzerland;
raw_author_name: Zhisong He
raw_affiliation_strings: Department of Biosystems Science and Engineering, ETH Zuerich, Basel, Switzerland;
raw_author_name: Mayar Ali
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Denise Jeridi
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Mihail Ivilinov Todorov
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Luciano Hoeher
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Sudharsan Padmarasu
raw_affiliation_strings: Core Facility Genomics (CF-GEN), Helmholtz Center Munich, Neuherberg, Germany;
raw_author_name: Ha Eun Park
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany;
raw_author_name: Justus Flinn Thevis
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany;
raw_author_name: Laura M. Bartos
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany;
raw_author_name: Inderjeet Singh
raw_affiliation_strings: Research Unit Adipocytes & Metabolism (ADM), Helmholtz Diabetes Center, Helmholtz Center    Munich, Neuherberg, Germany;
raw_author_name: Siegfried Ussar
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany;
raw_author_name: Kivanc Gorgulu
raw_affiliation_strings: Comprehensive Cancer Center Muenchen, Institute for Tumor Metabolism, TUM School of Medicine and Health, University Medical Center, Technical University of Munich, Germany;
raw_author_name: Hana Alguel
raw_affiliation_strings: Comprehensive Cancer Center Muenchen, Institute for Tumor Metabolism, TUM School of Medicine and Health, University Medical Center, Technical University of Munich, Germany;
raw_author_name: Kenny Roberts
raw_affiliation_strings: Wellcome Sanger Institute, Hinxton, Cambridge, UK;
raw_author_name: Omer A. Bayraktar
raw_affiliation_strings: Wellcome Sanger Institute, Hinxton, Cambridge, UK;
raw_author_name: Matthias Brendel
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany;
raw_author_name: Fabian J. Theis
raw_affiliation_strings: Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany;
raw_author_name: Barbara Treutlein
raw_affiliation_strings: Department of Biosystems Science and Engineering, ETH Zuerich, Basel, Switzerland;
raw_author_name: Aviv Regev
raw_affiliation_strings: Research & Early Development, Genentech, South San Francisco, CA, USA
raw_author_name: Ali Erturk
raw_affiliation_strings: Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany;