Clinical development of gene edited tacrolimus-resistant Treg (FKBP12 <sup>KO</sup> -Treg) to enable simultaneous immunosuppression and support of immune regulation
Year: 2025
Type: preprint
Topic: Renal Transplantation Outcomes and Treatments
Authors and affiliations:
raw_author_name: Ghazaleh Zarrinrad
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Lisa-Marie Burkhardt
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Dimitrios Laurin Wagner
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Stephan Schlickeiser
raw_affiliation_strings: BIH Center for Regenerative Therapies (BCRT), Charite - Universitaetsmedizin Berlin;
raw_author_name: Maik Stein
raw_affiliation_strings: Berlin Center for Regenerative Therapies, BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Désirée Jacqueline Wendering
raw_affiliation_strings: BIH Center for Regenerative Therapies (BCRT), Charite - Universitaetsmedizin Berlin;
raw_author_name: Lukas Ehlen
raw_affiliation_strings: Berlin Center for Regenerative Therapies, BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Gavin L. Kurgan
raw_affiliation_strings: Integrated DNA Technologies;
raw_author_name: Pawel Durek
raw_affiliation_strings: Deutsches Rheumaforschungszentrum, Leibniz Institut;
raw_author_name: Frederik Heinrich
raw_affiliation_strings: Deutsches Rheuma-Forschungszentrum Berlin;
raw_author_name: Anamika Giri
raw_affiliation_strings: Berlin Center for Regenerative Therapies, BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Kristy Ou
raw_affiliation_strings: Berlin Center for Regenerative Therapies, BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Henrike Hoffmann
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Sandra Muench
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Insa Stuewe
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Sven Dolling
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Oliver McCallion
raw_affiliation_strings: University of Oxford, John Radcliffe Hospital;
raw_author_name: Jaspal Kaeda
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Jonas Kath
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Sarah Schulenberg
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Abdolreza Nazari
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Lena Peter
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Samira Picht
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Rolf Turk
raw_affiliation_strings: Integrated DNA Technologies;
raw_author_name: Garrett Rettig
raw_affiliation_strings: Integrated DNA Technologies;
raw_author_name: Morgan Sturgeon
raw_affiliation_strings: Integrated DNA Technologies;
raw_author_name: Thomas L. Osborne
raw_affiliation_strings: Integrated DNA Technologies;
raw_author_name: Ashley Jacobi
raw_affiliation_strings: Integrated DNA Technologies, Inc.;
raw_author_name: Rebecca Friedrich
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Masako Monika Kaufmann
raw_affiliation_strings: Uniklinik Freiburg;
raw_author_name: Julia Klermund
raw_affiliation_strings: Uniklinik Freiburg;
raw_author_name: Simon Fink
raw_affiliation_strings: Natural and Medical Sciences Institute at the University of Tuebingen;
raw_author_name: Markus F. Templin
raw_author_name: Andy Roemhild
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Daniel Kaiser
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Oliver Klein
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Toni Cathomen
raw_affiliation_strings: Medical Center - University of Freiburg;
raw_author_name: Mir-Farzin Mashreghi
raw_affiliation_strings: Deutsches Rheuma-Forschungszentrum;
raw_author_name: Fadi Issa
raw_affiliation_strings: University of Oxford;
raw_author_name: Julia K. Polánsky
raw_affiliation_strings: BIH, Charite - Universitaetsmedizin Berlin
raw_author_name: Hans-Dieter Volk
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Michael Schmueck-Henneresse
raw_affiliation_strings: BIH, Charite-Universitaetsmedizin Berlin;
raw_author_name: Petra Reinke
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;
raw_author_name: Leila Amini
raw_affiliation_strings: Charite-Universitaetsmedizin Berlin;