Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System
Year: 2025
Type: article
Language: en
Topic: Cerebrospinal fluid and hydrocephalus
Authors and affiliations:
raw_author_name: Lei Jin
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Zeyu Yang
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Boyang Wei
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Yu Wu
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Longxiang Li
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Jiaming Zhou
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Xin Zhang
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Fa Jin
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Shixing Su
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Yanchao Liu
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Ran Li
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Shenquan Guo
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Xingwu Liu
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Yu Cai
raw_affiliation_strings: Nanomedicine Innovation Center Erasmus (NICE) Erasmus MC 3015 GD Rotterdam Netherlands
Nanomedicine Innovation Center Erasmus (NICE), Erasmus MC, 3015 GD Rotterdam, Netherlands
raw_author_name: Hong Liu
raw_affiliation_strings: State Key Laboratory of Antiviral Drugs Henan University  Zhengzhou 450046 China
Translational Medical Center of Huaihe Hospital Henan University  Kaifeng 475004 China
State Key Laboratory of Antiviral Drugs, Henan University, Zhengzhou, 450046 China
Translational Medical Center of Huaihe Hospital, Henan University, Kaifeng, 475004 China
raw_author_name: Min Chen
raw_affiliation_strings: Department of Neurosurgery The Second Affiliated Hospital Jiangxi Medical College Nanchang University Nanchang 330006 China
Department of Neurosurgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006 China
raw_author_name: Wenchao Liu
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Chuanzhi Duan
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China
raw_author_name: Xifeng Li
raw_affiliation_strings: Neurosurgery Center Department of Cerebrovascular Surgery The National Key Clinical Specialty Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration Zhujiang Hospital Institute for Brain Science and Intelligence Zhujiang Hospital, Southern Medical University Guangzhou 510282 China
Neurosurgery Center, Department of Cerebrovascular Surgery, The National Key Clinical Specialty, Engineering Research Center of Diagnostic and Therapeutic Technology and Devices for Cerebrovascular Diseases in Ministry of Education, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Zhujiang Hospital Institute for Brain Science and Intelligence, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282 China