Deep immune profiling pinpoints cellular and molecular drivers of lupus immunopathology
Year: 2025
Type: article
Topic: Single-cell and spatial transcriptomics
Authors and affiliations:
raw_author_name: Masahiro Nakano
raw_affiliation_strings: Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Michihiro Kono
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Kenichiro Asahara
raw_affiliation_strings: Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Takayuki Katsuyama
raw_affiliation_strings: Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
raw_author_name: Satoshi Kubo
raw_affiliation_strings: The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
raw_author_name: Eri Katsuyama
raw_affiliation_strings: Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Faculty of Health Science, Okayama University Medical School, Graduate School of Health Sciences, Okayama University, Okayama, Japan
raw_author_name: Yuya Fujita
raw_affiliation_strings: The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
raw_author_name: Takahiro Nishino
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Hajime Inokuchi
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Takahiro Arakawa
raw_affiliation_strings: Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Tsugumi Kawashima
raw_affiliation_strings: Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Shohei Noma
raw_affiliation_strings: Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Akiko Minowa
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
raw_author_name: Reza Bagherzadeh
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Yukiro Matsumoto
raw_affiliation_strings: Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Jun Inamo
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Haruka Takahashi
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Bunki Natsumoto
raw_affiliation_strings: Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Xuejun Zhang
raw_affiliation_strings: Department of Dermatology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Institute of Dermatology, Anhui Medical University, Hefei, Anhui, China
Key Laboratory of Dermatology (Anhui Medical University), Ministry of Education, Hefei, Anhui, China
raw_author_name: Sang-Cheol Bae
raw_affiliation_strings: Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea
Hanyang Institute of Bioscience and Biotechnology, Seoul, Korea
Hanyang University Institute for Rheumatology Research, Seoul, Korea
raw_author_name: Akari Suzuki
raw_affiliation_strings: Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Hiroaki Hatano
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Chikashi Terao
raw_affiliation_strings: Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan
Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
The Department of Applied Genetics, The School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan
raw_author_name: Yoshiya Tanaka
raw_affiliation_strings: Department of Molecular Targeted Therapeutics, University of Occupational and Environmental Health, Kitakyushu, Japan
The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan
raw_author_name: Yoshinori Matsumoto
raw_affiliation_strings: Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Kazuhiko Yamamoto
raw_affiliation_strings: Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Kazuyoshi Ishigaki
raw_affiliation_strings: Department of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan
Keio University Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q)
Laboratory for Human Immunogenetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan