Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling
Year: 2025
Type: article
Language: en
Topic: Cancer Cells and Metastasis
Authors and affiliations:
raw_author_name: Jueyao Zou
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Junfeng Shi
raw_affiliation_strings: Department of Oncology, Nanjing First Hospital of Nanjing Medical University, Nanjing, China
raw_author_name: Qiong Chen
raw_affiliation_strings: Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Ziyan Zhu
raw_affiliation_strings: Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Tongyao Hu
raw_affiliation_strings: Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Zhengyu Zhang
raw_affiliation_strings: Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Zhiqiang Pan
raw_affiliation_strings: School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Fei Xu
raw_affiliation_strings: School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Yong Zhu
raw_affiliation_strings: National Medical Centre of Colorectal Disease, The Third Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Yuanyuan Wu
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Yang Zhao
raw_affiliation_strings: Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Aiyun Wang
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Yin Lu
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China. luyingreen@njucm.edu.cn
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China. luyingreen@njucm.edu.cn
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. luyingreen@njucm.edu.cn
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China
raw_author_name: Yanhong Pan
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China. yanhongpan@njucm.edu.cn
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China. yanhongpan@njucm.edu.cn
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. yanhongpan@njucm.edu.cn
School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China. yanhongpan@njucm.edu.cn
School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China
raw_author_name: Wenxing Chen
raw_affiliation_strings: Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China. chenwx@njucm.edu.cn
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China. chenwx@njucm.edu.cn
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China. chenwx@njucm.edu.cn
Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China
Jiangsu Key Laboratory for Pharmacology and Safety Research of Chinese Materia Medica, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China
Jiangsu Joint International Research Laboratory of Chinese Medicine and Regenerative Medicine, Nanjing, China