In situ DC-primed vaccine combined with CD137 agonist elicits long-lasting antitumor immunity through cDC1-mediated tumor antigen-specific CD8 <sup>+</sup> T cell responses
Year: 2025
Type: article
Language: en
Topic: Immunotherapy and Immune Responses
Authors and affiliations:
raw_author_name: Mengjiao Wang
raw_affiliation_strings: Department of Pulmonary and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan, People's Republic of China
Institute of Modern Biology, Nanjing University, Nanjing, Jiangsu, People's Republic of China
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, Zigong, Sichuan, People's Republic of China
raw_author_name: Li Qiu
raw_affiliation_strings: Department of Thoracic Surgery, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University National Clinical Research Center for Respiratory Diseases, Guangzhou, Guangdong, People's Republic of China
State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Cheng Tang
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Danqing Huang
raw_affiliation_strings: Guangzhou Key Laboratory for Research and Development of Nano-Biomedical Technology for Diagnosis and Therapy &Guangdong Provincial Education Department Key Laboratory of Nano-Immunoregulation Tumor Microenvironment, Department of Oncology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Qiaocong Zheng
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Zunyi Li
raw_affiliation_strings: Department of Basic Medicine, Army Medical University, Chongqing, People's Republic of China
raw_author_name: Zhenhui Zhang
raw_affiliation_strings: Department of Thoracic Surgery, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University National Clinical Research Center for Respiratory Diseases, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Shupei Wei
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Lanfang Chen
raw_affiliation_strings: Department of Pulmonary and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan, People's Republic of China
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, Zigong, Sichuan, People's Republic of China
raw_author_name: Hongxin Huang
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Jun Liu
raw_affiliation_strings: Department of Thoracic Surgery, State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University National Clinical Research Center for Respiratory Diseases, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Junfeng Zhou
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Tao Lu
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Guanxin Liu
raw_affiliation_strings: Department of Pulmonary and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan, People's Republic of China
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
Department of Pulmonary and Critical Care Medicine, Zigong First People's Hospital, Zigong, Sichuan, People's Republic of China
raw_author_name: Yingjie Nie
raw_affiliation_strings: Shenzhen Key Laboratory for Cancer Metastasis and Personalized Therapy, Department of Clinical Oncology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong, People's Republic of China
raw_author_name: Qibin Leng
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institute of Cancer Research, The Affiliated Cancer Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China
raw_author_name: Tao Chen
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China