VAL-083 is effective in patients with newly-diagnosed MGMT-unmethylated glioblastoma: report of phase II study
Year: 2025
Type: article
Language: en
Topic: Glioma Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Chengcheng Guo
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Qunying Yang
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Meiling Deng
raw_affiliation_strings: Department of Radiation Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Xiaoling Qiu
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Shaoxiong Wu
raw_affiliation_strings: Department of Radiation Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Xiaojing Du
raw_affiliation_strings: Department of Radiation Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Ke Sai
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Ziyu Dai
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Zhenghe Chen
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China. chenzhp@sysucc.org.cn
raw_author_name: Ji Zhang
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Fuhua Lin
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Chao Ke
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Shaoyan Xi
raw_affiliation_strings: Department of Pathology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Wanming Hu
raw_affiliation_strings: Department of Pathology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Zhihuan Zhou
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Jiawei Li
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Xi Cao
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Yixiang Liao
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Yanchun Lv
raw_affiliation_strings: Department of Radiology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
raw_author_name: Dennis Brown
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA. dbrown@valenttech.com
Edison Oncology Holding Corp., Menlo Park, CA, USA. dbrown@valenttech.com
Valent Technologies, LLC, Menlo Park, CA, USA. dbrown@valenttech.com
DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
Edison Oncology Holding Corp., Menlo Park, CA, USA
raw_author_name: John Langlands
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
Valent Technologies, LLC, Menlo Park, CA, USA
raw_author_name: Gregory Johnson
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
raw_author_name: Jeffrey Bacha
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
Edison Oncology Holding Corp., Menlo Park, CA, USA
raw_author_name: Claire Kwan
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
raw_author_name: Sarath Kanekal
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
raw_author_name: Richard Schwartz
raw_affiliation_strings: DelMar Pharmaceuticals, Inc., Vancouver, Menlo Park, CA, USA
raw_author_name: Zhongping Chen
raw_affiliation_strings: Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China
Department of Neurosurgery/Neuro-Oncology, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, Guangdong, People's Republic of China. chenzhp@sysucc.org.cn