A Reproducible Sequence-Level Strategy to Enhance Peptide Immunogenicity While Preserving Wild-Type Epitope Recognition
Year: 2025
Type: article
Language: en
Topic: vaccines and immunoinformatics approaches
Authors and affiliations:
raw_author_name: Chia-Hung Chen
raw_affiliation_strings: Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan
Department of Medical Research, Hsinchu Municipal MacKay Children’s Hospital, Hsinchu 30068, Taiwan
raw_author_name: Yu-Chi Chiu
raw_affiliation_strings: Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan 33004, Taiwan
raw_author_name: Kai-Yao Huang
raw_affiliation_strings: Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan
Department of Medical Research, Hsinchu Municipal MacKay Children’s Hospital, Hsinchu 30068, Taiwan
Department of Medicine, MacKay Medical College, No. 46, Sec. 3, Zhongzheng Rd., New Taipei 25245, Taiwan
Institute of Biomedical Sciences, MacKay Medical College, New Taipei 25245, Taiwan
raw_author_name: Hsiao-Hsuan Huang
raw_affiliation_strings: Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, No. 75 Po-Ai Street, Hsinchu 30068, Taiwan
raw_author_name: Ta-Wei Kuo
raw_affiliation_strings: Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, No. 75 Po-Ai Street, Hsinchu 30068, Taiwan
raw_author_name: Yu-Chi Liu
raw_affiliation_strings: Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, No. 75 Po-Ai Street, Hsinchu 30068, Taiwan
raw_author_name: Hui-Ju Kao
raw_affiliation_strings: Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan
Department of Medical Research, Hsinchu Municipal MacKay Children’s Hospital, Hsinchu 30068, Taiwan
raw_author_name: Chen-Lin Yu
raw_affiliation_strings: Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan
Department of Medical Research, Hsinchu Municipal MacKay Children’s Hospital, Hsinchu 30068, Taiwan
raw_author_name: Shun-Long Weng
raw_affiliation_strings: Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, No. 75 Po-Ai Street, Hsinchu 30068, Taiwan
Department of Medicine, MacKay Medical College, No. 46, Sec. 3, Zhongzheng Rd., New Taipei 25245, Taiwan
Department of Nursing, Mackay Junior College of Medicine, Nursing and Management, Taipei 11260, Taiwan
Department of Obstetrics and Gynecology, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan
Department of Obstetrics and Gynecology, Hsinchu Municipal MacKay Children’s Hospital, Hsinchu 30068, Taiwan
Institute of Biomedical Sciences, MacKay Medical College, New Taipei 25245, Taiwan
raw_author_name: Kuang-Wen Liao
raw_affiliation_strings: Center for Intelligent Drug Systems and Smart Bio-Devices (IDS<sup>2</sup>B), National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan
Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, No. 75 Po-Ai Street, Hsinchu 30068, Taiwan
Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan 70101, Taiwan
Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
Institute of Molecular Medicine and Bioengineering, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu 30068, Taiwan
School of Dentistry, Kaohsiung Medical University, Kaohsiung 80708, Taiwan