Respiratory and Antinociceptive Effects of Nociceptin Receptor–µ-Opioid Receptor Agonist Cebranopadol versus Full Opioid Receptor Agonist Oxycodone: A Comparison in Healthy Volunteers
Year: 2025
Type: article
Language: en
Topic: Pain Management and Opioid Use
Authors and affiliations:
raw_author_name: Simone Jansen
raw_affiliation_strings: Simone Jansen, M.D., Ph.D.: Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands
Centre for Human Drug Research, Leiden, the Netherlands
raw_author_name: Erik Olofsen
raw_affiliation_strings: Erik Olofsen, Ph.D.: Centre for Human Drug Research, Leiden, The Netherlands; Department of Anesthesiology, Leiden University medical Center, Leiden, The Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands
raw_author_name: Laurence Moss
raw_affiliation_strings: Laurence Moss, M.D.: Centre for Human Drug Research, Leiden, The Netherlands; Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
Centre for Human Drug Research, Leiden, the Netherlands
raw_author_name: Joseph C. Grieco
raw_affiliation_strings: Joseph C. Grieco, Ph.D.: Tris Pharma, Inc., Monmouth Junction, New Jersey
Tris Pharma, Inc., Monmouth Junction, New Jersey, USA
raw_author_name: Marc L. Lesnick
raw_affiliation_strings: Marc L. Lesnick, Ph.D.: Tris Pharma, Inc., Monmouth Junction, New Jersey
Tris Pharma, Inc., Monmouth Junction, New Jersey, USA
raw_author_name: James C. Hackworth
raw_affiliation_strings: James C. Hackworth, Ph.D.: Tris Pharma, Inc., Monmouth Junction, New Jersey
Tris Pharma, Inc., Monmouth Junction, New Jersey, USA
raw_author_name: Monique van Velzen
raw_affiliation_strings: Monique van Velzen, Ph.D.: Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands; Department of Anesthesiology and Pain Medicine, Erasmus MC, Rotterdam the Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands
raw_author_name: Albert Dahan
raw_affiliation_strings: Albert Dahan, M.D., Ph.D.: Centre for Human Drug Research, Leiden, The Netherlands; MediD Consultancy BV, Amsterdam, The Netherlands; Outcomes Research Consortium, Houston, Texas
MediD Consultancy BV, Amsterdam, the Netherlands;
Centre for Human Drug Research, Leiden, the Netherlands
Outcomes Research Consortium, Houston, Texas, USA
raw_author_name: Elise Sarton
raw_affiliation_strings: Elise Sarton, M.D., Ph.D.: Department of Anesthesiology, Amsterdam University Medical Center, Amsterdam, The Netherlands
Department of Anesthesiology, Amsterdam University Medical Center, Amsterdam, the Netherlands
raw_author_name: Geert Jan Groeneveld
raw_affiliation_strings: Geert Jan Groeneveld, M.D., Ph.D.: Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands
Centre for Human Drug Research, Leiden, the Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands
raw_author_name: Marieke Niesters
raw_affiliation_strings: Marieke Niesters, M.D., Ph.D.: Department of Anesthesiology and Pain Medicine, Erasmus MC, Rotterdam, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands; Departement of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
Centre for Human Drug Research, Leiden, the Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands
raw_author_name: Rutger van der Schrier
raw_affiliation_strings: Rutger van der Schrier, M.D., Ph.D.: Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands
Department of Anesthesiology, Leiden University Medical Center, Leiden, the Netherlands