Radiosynthesis and Preclinical Evaluation of a Novel <sup>11</sup> C-Labeled Pyrazolopyrimidine Derivative for Positron Emission Tomography Imaging of Phosphodiesterase 2A
Year: 2025
Type: article
Language: en
Topic: Phosphodiesterase function and regulation
Authors and affiliations:
raw_author_name: Yinlong Li
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Wakana Mori
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Zhendong Song
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Tomoteru Yamasaki
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Taoqian Zhao
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Jiahui Chen
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Yiding Zhang
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Xin Zhou
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Lin Xie
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Tomomi Kokufuta
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Kuan Hu
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Qilong Hu
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Masayuki Fujinaga
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Xiaoyan Li
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Katsushi Kumata
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Chongjiao Li
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Zhenkun Sun
raw_affiliation_strings: Department of Pharmacology and Chemical Biology
Emory University School of Medicine
Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, United States
raw_author_name: Yabiao Gao
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
raw_author_name: Danielle E. Hoyle
raw_affiliation_strings: Department of Pharmacology and Chemical Biology
Emory University School of Medicine
Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, United States
raw_author_name: Jimmy S. Patel
raw_affiliation_strings: Department of Radiation Oncology
Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States
Winship Cancer Institute of Emory University
Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia 30322, United States
raw_author_name: Hongjie Yuan
raw_affiliation_strings: Department of Pharmacology and Chemical Biology
Emory University School of Medicine
Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia 30322, United States
raw_author_name: Ming-Rong Zhang
raw_affiliation_strings: Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences
National Institutes for Quantum Science and Technology
Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Sciences, National Institutes for Quantum Science and Technology, Chiba 263-8555, Japan
raw_author_name: Steven H. Liang
raw_affiliation_strings: Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, Georgia 30322, United States