Transcriptional dynamics of CD8+ T-cell exhaustion in immune checkpoint inhibitor resistance at single-cell resolution
Year: 2025
Type: article
Language: en
Topic: Cancer Immunotherapy and Biomarkers
Authors and affiliations:
raw_author_name: Tzu-Yang Tseng
raw_affiliation_strings: Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei, 106, Taiwan
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan
raw_author_name: Ching-Hung Hsieh
raw_affiliation_strings: Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan
raw_author_name: Hsuan-Cheng Huang
raw_affiliation_strings: Institute of Biomedical Informatics, National Yang Ming Chao Tung University, No. 155, Sec. 2, Linong St., 112, Taipei, Taiwan
raw_author_name: Yu-Ching Wu
raw_affiliation_strings: Department of Medical Research, National Taiwan University Hospital, No.7, Chung Shan S. Rd., Taipei, 100, Taiwan
raw_author_name: Chiun Hsu
raw_affiliation_strings: Center for Computational and Systems Biology, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan. chialanghsu@ntuh.gov.tw
Department of Medical Oncology, National Taiwan University Cancer Center, No. 57, Ln. 155, Sec. 3, Keelung Rd., 106, Taipei, Taiwan
Department of Medical Research, National Taiwan University Hospital, No.7, Chung Shan S. Rd., Taipei, 100, Taiwan. chialanghsu@ntuh.gov.tw
Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, No. 1, Sec. 1, Ren'ai Rd., 100, Taipei, Taiwan. chialanghsu@ntuh.gov.tw
Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan
Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan. chialanghsu@ntuh.gov.tw
raw_author_name: Chia-Lang Hsu
raw_affiliation_strings: Center for Computational and Systems Biology, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan. chialanghsu@ntuh.gov.tw
Department of Medical Oncology, National Taiwan University Cancer Center, No. 57, Ln. 155, Sec. 3, Keelung Rd., 106, Taipei, Taiwan
Department of Medical Research, National Taiwan University Hospital, No.7, Chung Shan S. Rd., Taipei, 100, Taiwan. chialanghsu@ntuh.gov.tw
Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, No. 1, Sec. 1, Ren'ai Rd., 100, Taipei, Taiwan. chialanghsu@ntuh.gov.tw
Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan
Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan. chialanghsu@ntuh.gov.tw
raw_author_name: Da-Liang Ou
raw_affiliation_strings: Graduate Institute of Oncology, National Taiwan University, No.2, Syujhou Rd., Taipei, 100, Taiwan. dlou@ntu.edu.tw
YongLin Institute of Health, National Taiwan University, No. 49, Fanglan Rd., 106, Taipei, Taiwan. dlou@ntu.edu.tw
raw_author_name: Hsueh-Fen Juan
raw_affiliation_strings: Center for Advanced Computing and Imaging in Biomedicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan. yukijuan@ntu.edu.tw
Center for Computational and Systems Biology, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan. yukijuan@ntu.edu.tw
Department of Life Science, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., Taipei, 106, Taiwan. yukijuan@ntu.edu.tw
Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, No. 1, Sec. 4, Roosevelt Rd., 106, Taipei, Taiwan. yukijuan@ntu.edu.tw