Discovery of isoindoline-2(1H)-carboxamide STING inhibitors as anti-inflammatory agents
Year: 2025
Type: article
Language: en
Topic: interferon and immune responses
Authors and affiliations:
raw_author_name: Xiaoqian Zhou
raw_affiliation_strings: Lingang Laboratory, Shanghai, 200031, People's Republic of China
School of Physical Science & Technology, ShanghaiTech University, Shanghai, 201210, People's Republic of China
Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
raw_author_name: Shumin Zang
raw_affiliation_strings: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China
raw_author_name: Shanyan Yao
raw_affiliation_strings: Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
raw_author_name: Hongfei Zhou
raw_affiliation_strings: Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China
raw_author_name: Xiyuan Wang
raw_affiliation_strings: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
raw_author_name: Meiyu Geng
raw_affiliation_strings: Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai, 264117, Shandong, People's Republic of China
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China
raw_author_name: Zhengsheng Zhan
raw_affiliation_strings: Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China. zszhan@simm.ac.cn
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. zszhan@simm.ac.cn
Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
raw_author_name: Zuoquan Xie
raw_affiliation_strings: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China. zqxie@simm.ac.cn
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. zqxie@simm.ac.cn
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
raw_author_name: Wenhu Duan
raw_affiliation_strings: Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China. whduan@simm.ac.cn
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. whduan@simm.ac.cn
Small-Molecule Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, People's Republic of China
University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China