Itreg cells Ameliorates MOG-induced brain inflammation via endowing DC tolerogenic capacity predominantly via TGF-beta signaling mediated AKT/mTOR pathway inhibition
Year: 2025
Type: article
Language: en
Topic: Neuroinflammation and Neurodegeneration Mechanisms
Authors and affiliations:
raw_author_name: Yang Luo
raw_affiliation_strings: Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Shanghai, 201600, China. ldyy_yluo@lzu.edu.cn
Department of Medicine, Division of Rheumatology, Penn State College of Medicine, Hershey, PA, USA. ldyy_yluo@lzu.edu.cn
Department of Neurology, The First Hospital of Lanzhou University, No.1 of Donggang West Road, Chengguan District, Lanzhou, Gansu Province, 730000, China. ldyy_yluo@lzu.edu.cn
Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu, 730000, China. ldyy_yluo@lzu.edu.cn
The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, 730000, China. ldyy_yluo@lzu.edu.cn
Department of Medicine, Division of Rheumatology, Penn State College of Medicine, Hershey, PA, USA. luoyanglyyy@126.com
The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, 730000, China. luoyanglyyy@126.com
Department of Neurology, The First Hospital of Lanzhou University, No.1 of Donggang West Road, Chengguan District, Lanzhou, Gansu Province, 730000, China. luoyanglyyy@126.com
Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Shanghai, 201600, China. luoyanglyyy@126.com
Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu, 730000, China. luoyanglyyy@126.com
raw_author_name: Yating Li
raw_affiliation_strings: The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, 730000, China
raw_author_name: Jiale Tian
raw_affiliation_strings: The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, 730000, China
raw_author_name: Haolin Li
raw_affiliation_strings: Rheumatic Bone Disease Center, Gansu Hospital of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, 730000, China
raw_author_name: Yong Wang
raw_affiliation_strings: The First Clinical Medical College, Lanzhou University, Lanzhou, Gansu, 730000, China
raw_author_name: Xiaofeng Wei
raw_affiliation_strings: Key Laboratory of Biotherapy and Regenerative Medicine, Lanzhou, Gansu, 730000, China
raw_author_name: Long Zhang
raw_affiliation_strings: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Lanzhou University, Lanzhou, Gansu, 730000, China
raw_author_name: David Brand
raw_affiliation_strings: Research Service, Lt. Col. Luke Weathers, Jr. VA Medical Center, Memphis, TN, 38104, USA
raw_author_name: Songguo Zheng
raw_affiliation_strings: Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Shanghai, 201600, China. Song.Zheng@shsmu.edu.cn
Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Songjiang Research Institute of Shanghai Jiaotong University School of Medicine, 227 Chongqing South Road, Shanghai, 200025, China. Song.Zheng@shsmu.edu.cn
Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Shanghai, 201600, China. songguozhengzsg@126.com
Department of Immunology, School of Cell and Gene Therapy, Shanghai Jiao Tong University, Songjiang Research Institute of Shanghai Jiaotong University School of Medicine, 227 Chongqing South Road, Shanghai, 200025, China. songguozhengzsg@126.com