Chlorotonils exhibit potent activity against <i>Mycobacterium tuberculosis</i> , while resistance is mediated by MmpR5-MmpL5
Year: 2025
Type: preprint
Topic: Tuberculosis Research and Epidemiology
Authors and affiliations:
raw_author_name: Felix Deschner
raw_affiliation_strings: Helmholtz Institute for Pharmaceutical Research Saarland;
Helmholtz Institute for Pharmaceutical Research Saarland
raw_author_name: Melissa D Chengalroyen
raw_affiliation_strings: University of Cape Town;
University of Cape Town
raw_author_name: Lauren Ames
raw_affiliation_strings: Seattle Children's Research Institute;
Seattle Children's Research Institute
raw_author_name: Diana Quach
raw_affiliation_strings: Linnaeus Bioscience Inc;
Linnaeus Bioscience Inc
raw_author_name: Rodrigo Aguilera Olvera
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Barbara Bosch
raw_affiliation_strings: The Rockefeller University;
The Rockefeller University
raw_author_name: Anthony Castro
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Heather Kim
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Kaushik Raman
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Natalie Thornton
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Joshua Wallach
raw_affiliation_strings: Weill Cornell Medical College;
Weill Cornell Medical College
raw_author_name: Fernanda Rodrigues da Costa
raw_affiliation_strings: Seattle Children's Research Institute;
Seattle Children's Research Institute
raw_author_name: Renee Allen
raw_affiliation_strings: Seattle Children's Research Institute;
Seattle Children's Research Institute
raw_author_name: Andréanne Lupien
raw_affiliation_strings: McGill University;
McGill University
raw_author_name: Mandisa Zuma
raw_affiliation_strings: University of Cape Town;
University of Cape Town
raw_author_name: Sasha Lynch
raw_affiliation_strings: University of Cape Town;
University of Cape Town
raw_author_name: Joe Pogliano
raw_affiliation_strings: University of California;
University of California
raw_author_name: Joseph Sugie
raw_affiliation_strings: Seattle Children's Research Institute;
Seattle Children's Research Institute
raw_author_name: Jeremy M Rock
raw_affiliation_strings: Rockefeller University;
Rockefeller University
raw_author_name: Dirk Schnappinger
raw_affiliation_strings: Weill Cornell Medical College, New York
raw_author_name: Tanya Parish
raw_affiliation_strings: Seattle Children's Research Institute;
Seattle Children's Research Institute
raw_author_name: Valerie Mizrahi
raw_affiliation_strings: University of Cape Town;
University of Cape Town
raw_author_name: Michael DeJesus
raw_affiliation_strings: The Rockefeller University;
The Rockefeller University
raw_author_name: Rolf Müller
raw_affiliation_strings: Helmholtz Institute for Pharmaceutical Research Saarland
raw_author_name: Jennifer Herrmann
raw_affiliation_strings: Helmholtz Institute for Pharmaceutical Research Saarland;
Helmholtz Institute for Pharmaceutical Research Saarland