Geminin inhibits DNA replication licensing by sterically blocking CDT1-MCM2 interactions
Year: 2025
Type: article
Language: en
Topic: DNA Repair Mechanisms
Authors and affiliations:
raw_author_name: Joshua Tomkins
raw_affiliation_strings: Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London, UK
Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Lucy V. Edwardes
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Sarah V. Faull
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Matthew Peach
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Peter J. Gillespie
raw_affiliation_strings: Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK
School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK
raw_author_name: Vera Leber
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Anna Schmidt
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Halil Bounoua
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Nicholas Sim
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: Rosa Camarillo
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
MRC Laboratory of Medical Sciences (LMS), London, UK
raw_author_name: J. Julian Blow
raw_affiliation_strings: Division of Molecular, Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, UK
School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK
raw_author_name: Alexis R. Barr
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. a.barr@lms.mrc.ac.uk
MRC Laboratory of Medical Sciences (LMS), London, UK. a.barr@lms.mrc.ac.uk
raw_author_name: Anna Barnard
raw_affiliation_strings: Department of Chemistry, Molecular Sciences Research Hub, Imperial College London, London, UK. a.barnard@imperial.ac.uk
raw_author_name: Christian Speck
raw_affiliation_strings: Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. chris.speck@imperial.ac.uk
MRC Laboratory of Medical Sciences (LMS), London, UK. chris.speck@imperial.ac.uk