Structures of human glucose-6-phosphate transporter reveal reciprocal antiport mechanism driving glucose-6-phosphate and inorganic phosphate exchange
Year: 2025
Type: article
Language: en
Topic: Glycogen Storage Diseases and Myoclonus
Authors and affiliations:
raw_author_name: Qian Wang
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
raw_author_name: Ningjie Guo
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
raw_author_name: Yunxiang Du
raw_affiliation_strings: New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, China
raw_author_name: Junwu Liu
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Wanting Ai
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Fengyi Yang
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Yuanzai Zhu
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Yuanyuan Zhao
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
School of Basic Medical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Di Wu
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
School of Basic Medical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Lei Liu
raw_affiliation_strings: New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, China. lliu@tsinghua.edu.cn
New Cornerstone Science Laboratory, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Center for Synthetic and Systems Biology, Department of Chemistry, Tsinghua University, Beijing, China
raw_author_name: Xia Yao
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China. xia_yao@whu.edu.cn
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. xia_yao@whu.edu.cn
Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China
raw_author_name: Shuai Gao
raw_affiliation_strings: Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China. gaoshuai812@whu.edu.cn
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China. gaoshuai812@whu.edu.cn
Department of Urology, Zhongnan Hospital of Wuhan University, State Key Laboratory of Metabolism and Regulation in Complex Organisms, School of Pharmaceutical Sciences, Wuhan University, Wuhan, China
Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, China