Enhanced glioblastoma immunotherapy via SMAC mimetic dose escalation and TGFβ blockade
Year: 2025
Type: article
Language: en
Topic: Glioma Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Kyle Malone
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
Ottawa Institute of Systems Biology University of Ottawa , Ottawa, Ontario K1H 8M5,
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
raw_author_name: Melanie Dugas
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
raw_author_name: Nathalie Earl
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
Ottawa Institute of Systems Biology University of Ottawa , Ottawa, Ontario K1H 8M5,
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
raw_author_name: Tommy Alain
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
Ottawa Institute of Systems Biology University of Ottawa , Ottawa, Ontario K1H 8M5,
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
raw_author_name: Robert G Korneluk
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
raw_author_name: Eric LaCasse
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
raw_author_name: Shawn T Beug
raw_affiliation_strings: Apoptosis Research Centre, Children’s Hospital of Eastern Ontario Research Institute , Ottawa, Ontario K1H 8L1,
Centre for Infection, Immunity and Inflammation, University of Ottawa , Ottawa, Ontario K1H 8M5,
Department of Biochemistry, Microbiology and Immunology, University of Ottawa , Ottawa, Ontario K1H 8M5,
Ottawa Institute of Systems Biology University of Ottawa , Ottawa, Ontario K1H 8M5,
Children's Hospital of Eastern Ontario Research Institute Apoptosis Research Centre, , 401 Smyth Road, Ottawa, Ontario, Canada, K1H 8L1
University of Ottawa Department of Biochemistry, Microbiology and Immunology, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5
University of Ottawa Centre for Infection, Immunity and Inflammation, , 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5