A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription
Year: 2025
Type: article
Language: en
Topic: BRCA gene mutations in cancer
Authors and affiliations:
raw_author_name: Anna Minello
raw_affiliation_strings: Institut Curie, Université PSL CNRS UMR3348, Orsay, France
Université Paris-Saclay CNRS UMR3348, Orsay, France
raw_author_name: Jesus Gomez-Escudero
raw_affiliation_strings: Genome Instability and Cancer Predisposition Laboratory, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain
raw_author_name: Sreerama Chaitanya Sridhara
raw_affiliation_strings: Genome Instability and Cancer Predisposition Laboratory, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain
raw_author_name: Charlotte Martin
raw_affiliation_strings: Institut Curie, Université PSL CNRS UMR3348, Orsay, France
Université Paris-Saclay CNRS UMR3348, Orsay, France
raw_author_name: Elodie Girard
raw_affiliation_strings: CBIO-Centre for Computational Biology, INSERM U900, Mines ParisTech, Paris, France
raw_author_name: Juan C. Cañas
raw_affiliation_strings: Genome Instability and Cancer Predisposition Laboratory, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain
raw_author_name: Yasin Memari
raw_affiliation_strings: Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK
Early Cancer Institute, University of Cambridge, Cambridge, UK
raw_author_name: Maria Rose Bustos
raw_affiliation_strings: BioMedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Cancer Research Laboratory, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
raw_author_name: Antonio Galarreta
raw_affiliation_strings: Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland
raw_author_name: Virginie Boucherit
raw_affiliation_strings: Institut Curie, Université PSL CNRS UMR3348, Orsay, France
Université Paris-Saclay CNRS UMR3348, Orsay, France
raw_author_name: Evgeny Imyanitov
raw_affiliation_strings: N.N. Petrov National Medical Research Center of Oncology, Saint Petersburg, Russia
raw_author_name: Sigridur Klara Bodvarsdottir
raw_affiliation_strings: BioMedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland
raw_author_name: Sylvain Baulande
raw_affiliation_strings: Institut Curie, PSL University, ICGex Next-Generation Sequencing Platform, Paris, France
raw_author_name: Anne Vincent-Salomon
raw_affiliation_strings: Diagnostic and Theragnostic Medicine Division, Institut Curie, Paris, France, Institut Curie, Paris, France
raw_author_name: Nicolas Servant
raw_affiliation_strings: CBIO-Centre for Computational Biology, INSERM U900, Mines ParisTech, Paris, France
raw_author_name: Matthias Altmeyer
raw_affiliation_strings: Department of Molecular Mechanisms of Disease, University of Zurich, Zurich, Switzerland
raw_author_name: Stefan Sigurdsson
raw_affiliation_strings: BioMedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Cancer Research Laboratory, Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland
raw_author_name: Dominique Stoppa-Lyonnet
raw_affiliation_strings: Department of Genetics, Institut Curie, Paris, France
INSERM U830 Institut Curie, Paris, France
Paris-Cité University, Paris, France
raw_author_name: Serena Nik-Zainal
raw_affiliation_strings: Academic Department of Medical Genetics, School of Clinical Medicine, University of Cambridge, Cambridge, UK
Early Cancer Institute, University of Cambridge, Cambridge, UK
raw_author_name: Aura Carreira
raw_affiliation_strings: Genome Instability and Cancer Predisposition Laboratory, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain. acarreira@cbm.csic.es
Institut Curie, Université PSL CNRS UMR3348, Orsay, France. acarreira@cbm.csic.es
Université Paris-Saclay CNRS UMR3348, Orsay, France. acarreira@cbm.csic.es
Genome Instability and Cancer Predisposition Laboratory, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Madrid, Spain
Institut Curie, Université PSL CNRS UMR3348, Orsay, France
Université Paris-Saclay CNRS UMR3348, Orsay, France