Chimeras co-targeting antigens and FcγRIIb trigger degradation of extracellular soluble proteins and pathological aggregates
Year: 2025
Type: article
Language: en
Topic: Monoclonal and Polyclonal Antibodies Research
Authors and affiliations:
raw_author_name: Mingjuan Du
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
raw_author_name: Na Li
raw_affiliation_strings: Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin, PR China
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Tianqi Li
raw_affiliation_strings: Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin, PR China
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Zhuoqian Zhao
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
raw_author_name: Huanzhen Liu
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
raw_author_name: Xin Li
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Nanxin Gong
raw_affiliation_strings: Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin, PR China
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Baoxin Duan
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Wenli Wang
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Yi Jian
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Wenxuan Ma
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Xiaoqi Zhang
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Yi Wang
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Zhaoyuan Zhang
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Yiyang Bai
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Xiaoqian Wang
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Chunlei Wang
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Jinming Liu
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Xiangchen Guan
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Feilong Zhou
raw_affiliation_strings: State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Wei Wang
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China
raw_author_name: Lili Li
raw_affiliation_strings: Beijing Institute of Biological Products Co., Ltd, Beijing, PR China
raw_author_name: Xingping Zhu
raw_affiliation_strings: EVIDENT(Shanghai) Co., Ltd, Shanghai, PR China
raw_author_name: Ying Lei
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
raw_author_name: Yinkai Duan
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China
raw_author_name: Guoge Han
raw_affiliation_strings: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science and Nankai University affliated Tianjin Eye Hospital, Tianjin, PR China
raw_author_name: Pinghui Wei
raw_affiliation_strings: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science and Nankai University affliated Tianjin Eye Hospital, Tianjin, PR China
raw_author_name: Shan Gao
raw_affiliation_strings: Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science and Nankai University affliated Tianjin Eye Hospital, Tianjin, PR China
raw_author_name: Sheng Wang
raw_affiliation_strings: Shanghai Zelixir Biotech Company Ltd, Shanghai, PR China
raw_author_name: Ancheng Chen
raw_affiliation_strings: Shanghai Zelixir Biotech Company Ltd, Shanghai, PR China
raw_author_name: Yi Huang
raw_affiliation_strings: Analytical Science Department, Shanghai Tanshi Biotech Company Ltd, Shanghai, PR China
raw_author_name: Haitao Yang
raw_affiliation_strings: Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China. yanght@shanghaitech.edu.cn
raw_author_name: Xue Xue
raw_affiliation_strings: Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin, PR China. xuexue@nankai.edu.cn
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China. xuexue@nankai.edu.cn
raw_author_name: Hongkai Zhang
raw_affiliation_strings: Academy for Advanced Interdisciplinary Studies, Nankai University, Tianjin, PR China. hongkai@nankai.edu.cn
Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, PR China. hongkai@nankai.edu.cn
State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and College of Pharmacy, Nankai University, Tianjin, PR China. hongkai@nankai.edu.cn