CAR T cells targeting CCR4 selectively deplete human Tregs ex vivo and in vivo
Year: 2025
Type: article
Language: en
Topic: T-cell and B-cell Immunology
Authors and affiliations:
raw_author_name: Caitlin M. Tilsed
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Karen P. Fong
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Xinyi Shi
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Tatiana Akimova
raw_affiliation_strings: 3Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
raw_author_name: Liqing Wang
raw_affiliation_strings: 3Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
raw_author_name: Estela Noguera-Ortega
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Ryan Krouse
raw_affiliation_strings: 4Division of Thoracic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Andres Bermudez
raw_affiliation_strings: 4Division of Thoracic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Sunil Singhal
raw_affiliation_strings: 4Division of Thoracic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Regina Young
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Evgeniy Eruslanov
raw_affiliation_strings: 4Division of Thoracic Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
University of Pennsylvania, Philadelphia, Pennsylvania, United States
raw_author_name: Keisuke Watanabe
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
The University of Pennsylvania, United States
raw_author_name: Wayne W. Hancock
raw_affiliation_strings: 3Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children’s Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
raw_author_name: Carl H. June
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States
raw_author_name: Steven M. Albelda
raw_affiliation_strings: 1Center for Cellular Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, United States