The PIK3CA/AKT pathway drives therapy resistance in rhabdomyosarcoma
Year: 2025
Type: article
Language: en
Topic: PI3K/AKT/mTOR signaling in cancer
Authors and affiliations:
raw_author_name: Qiqi Yang
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Institute of Molecular and Cell Biology, Agency for Science, Technology, and Resesarch (A*STAR), Singapore, Singapore
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Yueyang Wang
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Luis A. Corchete Sanchez
raw_affiliation_strings: Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Sabateeshan Mathavarajah
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Qian Qin
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA, USA
Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Yun Wei
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Eric Alpert
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Lauren Whelton
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Priyanshu Sharma
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Stephanie Strom
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Ilyas Oultache
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: A. John Iafrate
raw_affiliation_strings: Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Luca Pinello
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Esther Rheinbay
raw_affiliation_strings: Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
raw_author_name: Chuan Yan
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA. yan_chuan@a-star.edu.sg
Institute of Molecular and Cell Biology, Agency for Science, Technology, and Resesarch (A*STAR), Singapore, Singapore. yan_chuan@a-star.edu.sg
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. yan_chuan@a-star.edu.sg
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA. yan_chuan@a-star.edu.sg
Institute of Molecular and Cell Biology, Agency for Science, Technology, and Resesarch (A*STAR), Singapore, Singapore
raw_author_name: David M. Langenau
raw_affiliation_strings: Harvard Stem Cell Institute, Cambridge, MA, USA. dlangenau@mgh.harvard.edu
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. dlangenau@mgh.harvard.edu
Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA. dlangenau@mgh.harvard.edu
Harvard Stem Cell Institute, Cambridge, MA, USA
Krantz Family Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA