Targeting high-risk MYC-overexpressed osteosarcoma with an Aurora kinase inhibitor:--results from a pilot umbrella trial
Year: 2025
Type: article
Language: en
Topic: Sarcoma Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Kai Tian
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
raw_author_name: Yafei Jiang
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Mengxiong Sun
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Yu Lv
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Jean Fan
raw_affiliation_strings: TransThera Sciences (US), Inc, Gaithersburg, MA, USA
raw_author_name: Caixia Sun
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Yujia Zhu
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Yingying Yu
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Xiaoyan Qiang
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Peng Peng
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Frank Wu
raw_affiliation_strings: TransThera Sciences (Nanjing), Inc, Nanjing, China
raw_author_name: Weisong Zhao
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Dongqing Zuo
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
raw_author_name: Hongsheng Wang
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Chongren Wang
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
raw_author_name: Wei Sun
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Jinzeng Wang
raw_affiliation_strings: National Research Center for Translational Medicine at Shanghai, State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. jz.wang@sjtu.edu.cn
National Research Center for Translational Medicine at Shanghai, State Key Laboratory of Medical Genomics, Shanghai Institute of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Zhengdong Cai
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China. czd856@vip.163.com
Shanghai Bone Tumor Institution, Shanghai, China
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Yingqi Hua
raw_affiliation_strings: Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Bone Tumor Institution, Shanghai, China. hua_yingqi@163.com
Department of Orthopedic Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Bone Tumor Institution, Shanghai, China