Immunotherapy Inhibits Tumor Cholesterol Synthesis via the IFNγ–IRF1–SREBF2 Axis
Year: 2025
Type: article
Language: en
Topic: Cancer, Lipids, and Metabolism
Authors and affiliations:
raw_author_name: Liping Xu
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
raw_author_name: Xiaomin Zhang
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
raw_author_name: Xiaowei Lai
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, China
raw_author_name: Hongyuan Chen
raw_affiliation_strings: 2Department of Pathogenic Biology and Immunology, School of Life Science and Biopharmaceutical, Guangdong Pharmaceutical University, Guangzhou, China
Guangdong Pharmaceutical University, Guangzhou, China
raw_author_name: Shuangye Liao
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
raw_author_name: Mingzeng Chang
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
raw_author_name: Xiaoqing Wu
raw_affiliation_strings: 2Department of Pathogenic Biology and Immunology, School of Life Science and Biopharmaceutical, Guangdong Pharmaceutical University, Guangzhou, China
Guangdong Pharmaceutical University, Guangzhou, China
raw_author_name: Wen Rui
raw_affiliation_strings: 3Center for Novel Drug Research and Development, Guangdong Pharmaceutical University, Guangzhou, China
Guangdong Pharmaceutical University, Guangzhou, China
raw_author_name: Juan Yang
raw_affiliation_strings: 4Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
Hunan University of Medicine, Hunan, China
raw_author_name: Danyang Wang
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, China
raw_author_name: Chengqi Gao
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Nanchang University, Nanchang, Jiangxi, China
raw_author_name: Ziqian Fang
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China
raw_author_name: Jianeng Zhang
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Guangzhou, China
raw_author_name: Wende Li
raw_affiliation_strings: 5Guangdong Laboratory Animals Monitoring Institute, Guangdong Key Laboratory of Laboratory Animals, Guangzhou, China
Guangdong Laboratory Animals Monitoring Institute, China
raw_author_name: Bo Li
raw_affiliation_strings: 6Department of Biochemistry and Molecular Biology, Cancer Research Institute, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China
Southern Medical University, Guangzhou, China
raw_author_name: Xiaojun Xia
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
raw_author_name: Penghui Zhou
raw_affiliation_strings: 1State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China
Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China