Osimertinib activates a TGF-β2–dependent secretory program that drives lung adenocarcinoma progression
Year: 2025
Type: article
Language: en
Topic: Lung Cancer Treatments and Mutations
Authors and affiliations:
raw_author_name: Madhurima Ghosh
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Chao Wu
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Abhishek Kumar
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Monique Nilsson
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: John V. Heymach
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Weina Zhao
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Jiang Yu
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Xin Liu
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Na Ding
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Shike Wang
raw_affiliation_strings: Section of Hematology and Medical Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
Tulane Cancer Center, Louisiana Cancer Research Center, New Orleans, Louisiana, USA
Section of Hematology and Medical Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, United States of America
raw_author_name: Guan-Yu Xiao
raw_affiliation_strings: Department of Toxicology and Cancer Biology, The University of Kentucky, Lexington, Kentucky, USA
Department of Toxicology and Cancer Biology, The University of Kentucky, Lexington, United States of America
raw_author_name: Angelo Chen
raw_affiliation_strings: Department of Biosciences, Rice University, Houston, Texas, USA
Department of Biosciences, Rice University, Houston, United States of America
raw_author_name: Kate Grimley
raw_affiliation_strings: Department of Chemistry, Texas A&M University, College Station, Texas, USA
Department of Chemistry, Texas A&M University, College Station, United States of America
raw_author_name: William K. Russell
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, Texas, USA
Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, United States of America
raw_author_name: Chad J. Creighton
raw_affiliation_strings: Department of Medicine and Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Texas, USA
Department of Medicine and Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, United States of America
raw_author_name: Xiaochao Tan
raw_affiliation_strings: Section of Hematology and Medical Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
Tulane Cancer Center, Louisiana Cancer Research Center, New Orleans, Louisiana, USA
Section of Hematology and Medical Oncology, Department of Medicine, Tulane University School of Medicine, New Orleans, United States of America
raw_author_name: Jonathan M. Kurie
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas-MD Anderson Cancer Center, Houston, Texas, USA
Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, United States of America