Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities
Year: 2025
Type: article
Language: en
Topic: Photoreceptor and optogenetics research
Authors and affiliations:
raw_author_name: Lennart Roos
raw_affiliation_strings: Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Department of Otolaryngology, University Medical Center Göttingen, 37075, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Aida Garrido-Charles
raw_affiliation_strings: Advanced Optogenes Group, Institute for Auditory Neuroscience, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Cardiovascular Physiology, University Medical Center Göttingen, Göttingen, Germany
raw_author_name: Niels Albrecht
raw_affiliation_strings: Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Anna Vavakou
raw_affiliation_strings: Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Alexey Alekseev
raw_affiliation_strings: Advanced Optogenes Group, Institute for Auditory Neuroscience, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Martina Bleyer
raw_affiliation_strings: Laboratory Animal Science Unit, Pathology, German Primate Center, Leibniz Institute for Primate Research, 37077, Goettingen, Germany
raw_author_name: Anupriya Thirumalai
raw_affiliation_strings: Auditory Circuit lab, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Artur Mittring
raw_affiliation_strings: Auditory Circuit lab, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Theocharis Alvanos
raw_affiliation_strings: Auditory Neuroscience and Synaptic Nanophysiology Group, Max-Planck-Institute for Multidisciplinary Sciences, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Collaborative Research Center SFB 1286 "Quantitative Synaptology", University of Göttingen, 37073, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Antoine T Huet
raw_affiliation_strings: Auditory Circuit lab, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Ernst Bamberg
raw_affiliation_strings: Max Plank Institute for Biophysics, Frankfurt am Main, Germany
raw_author_name: Kathrin Kusch
raw_affiliation_strings: Auditory Circuit lab, Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Collaborative Research Center SFB 1690 "Disease mechanisms and functional restoration of sensory and motor systems", University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Functional Auditory Genomics Group, Auditory Neuroscience and Optogenetics laboratory, German Primate Center, 37077, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Bettina J Wolf
raw_affiliation_strings: Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Tobias Moser
raw_affiliation_strings: Auditory Neuroscience and Synaptic Nanophysiology Group, Max-Planck-Institute for Multidisciplinary Sciences, 37075, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Collaborative Research Center SFB 1286 "Quantitative Synaptology", University of Göttingen, 37073, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Collaborative Research Center SFB 1690 "Disease mechanisms and functional restoration of sensory and motor systems", University of Göttingen, 37073, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany. tobias.moser@mpinat.mpg.de
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany
Collaborative Research Center SFB 1690 "Disease mechanisms and functional restoration of sensory and motor systems", University of Göttingen, 37073, Göttingen, Germany
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Thomas Mager
raw_affiliation_strings: Advanced Optogenes Group, Institute for Auditory Neuroscience, University Medical Center Göttingen, 37075, Göttingen, Germany. thomas.mager@med.uni-goettingen.de
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany. thomas.mager@med.uni-goettingen.de
Collaborative Research Center SFB 1690 "Disease mechanisms and functional restoration of sensory and motor systems", University of Göttingen, 37073, Göttingen, Germany. thomas.mager@med.uni-goettingen.de
Else Kröner Fresenius Center for Optogenetic Therapies, University Medical Center Göttingen, 37075, Göttingen, Germany. thomas.mager@med.uni-goettingen.de
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany. thomas.mager@med.uni-goettingen.de
Advanced Optogenes Group, Institute for Auditory Neuroscience, University Medical Center Göttingen, 37075, Göttingen, Germany
Institute for Auditory Neuroscience and InnerEarLab, University Medical Center Göttingen, 37075, Göttingen, Germany
Cluster of Excellence "Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells" (MBExC), University of Göttingen, 37073, Göttingen, Germany