Targeting fibroblast activation protein in solid tumors via LNP-mediated CAR-mRNA delivery promotes durable regression in murine models
Year: 2025
Type: article
Language: en
Topic: Macrophage Migration Inhibitory Factor
Authors and affiliations:
raw_author_name: Sikun Meng
raw_affiliation_strings: Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Tomoaki Hara
raw_affiliation_strings: Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Tetsuya Sato
raw_affiliation_strings: Biomedical Research Center, Faculty of Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama, 350-1241, Japan
raw_author_name: Shotaro Tatekawa
raw_affiliation_strings: Department of Radiation Oncology, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Yasuko Arao
raw_affiliation_strings: Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Yoshiko Saito
raw_affiliation_strings: Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Toshiro Hirai
raw_affiliation_strings: Vaccine Creation Group, BIKEN Innovative Vaccine Research Alliance Laboratories, Research Institute for Microbial Diseases, The University of Osaka, Yamadaoka 2-1, Suita, Osaka, 565-0871, Japan
raw_author_name: Daisuke Motooka
raw_affiliation_strings: Research Institute for Microbial Diseases, The University of Osaka, Yamadaoka 3-1, Suita, Osaka, 565-0871, Japan
raw_author_name: Sarah Rennie
raw_affiliation_strings: Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, DK2200 Copenhagen N, Copenhagen, Denmark
raw_author_name: Taroh Satoh
raw_affiliation_strings: Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Kazuhiko Ogawa
raw_affiliation_strings: Department of Radiation Oncology, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Yutaka Miura
raw_affiliation_strings: Department of Life Science and Technology, School of Life Science and Technology, Institute of Science Tokyo, 4259 Nagatsutacho, Midori-ku, Yokohama, Kanagawa, 226-8501, Japan
Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo, 4259 Nagatsutacho, Midori-ku, Yokohama, Kanagawa, 226-8501, Japan
raw_author_name: Masaki Mori
raw_affiliation_strings: Tokai University Graduate School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan
raw_author_name: Yuichiro Doki
raw_affiliation_strings: Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Hidetoshi Eguchi
raw_affiliation_strings: Department of Gastroenterological Surgery, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan
raw_author_name: Hideshi Ishii
raw_affiliation_strings: Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan. hishii@gesurg.med.osaka-u.ac.jp
Department of Medical Data Science, Center of Medical Innovation and Translational Research, Graduate School of Medicine, The University of Osaka, Yamadaoka 2-2, Suita, Osaka, 565-0871, Japan