Accurate prediction of gain- and loss-of-function variants in GABA <sub>A</sub> receptors
Year: 2025
Type: article
Topic: Neuroscience and Neuropharmacology Research
Authors and affiliations:
raw_author_name: Christian M. Boßelmann
raw_affiliation_strings: Department for Neurology and Epileptology, Member of ERN EpiCARE, Hertie Institute for Clinical Brain Research and Hertie Center of Neurology, University Hospital Tübingen, 72076, Tübingen, Germany
raw_author_name: Sebastian Ortiz
raw_affiliation_strings: Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 4293, Dianalund, Denmark
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 5230, Odense, Denmark
Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 493, Dianalund, Denmark
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 520, Odense, Denmark
raw_author_name: Rebekka Staal Dahl
raw_affiliation_strings: Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 4293, Dianalund, Denmark
Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, 77030, Houston, TX, United States
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 5230, Odense, Denmark
Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 493, Dianalund, Denmark
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 520, Odense, Denmark
raw_author_name: Vivian W. Y. Liao
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Serene El-Kamand
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Susan X. N. Lin
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Anthony Sze Hon Kan
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Tobias Brünger
raw_affiliation_strings: Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, 77030, Houston, TX, United States
raw_author_name: Dennis Lal
raw_affiliation_strings: Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, 77030, Houston, TX, United States
Epilepsy Center, Neurological Institute, Cleveland Clinic, 44195, Cleveland, OH, United States
Program in Medical and Population Genetics, Broad Institute of Massachusetts Institute of Technology (M.I.T.) and Harvard, 02142, Cambridge, MA, United States
Stanley Center for Psychiatric Research, Broad Institute of Harvard and M.I.T, 02142, Cambridge, MA, United States
raw_author_name: Holger Lerche
raw_affiliation_strings: Department for Neurology and Epileptology, Member of ERN EpiCARE, Hertie Institute for Clinical Brain Research and Hertie Center of Neurology, University Hospital Tübingen, 72076, Tübingen, Germany
raw_author_name: Jules Kreuer
raw_affiliation_strings: Department of Computer Science, Methods in Medical Informatics, University of Tuebingen, 72076, Tuebingen, Germany
raw_author_name: Nico Pfeifer
raw_affiliation_strings: Department of Computer Science, Methods in Medical Informatics, University of Tuebingen, 72076, Tuebingen, Germany
raw_author_name: Mary Chebib
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Nathan L. Absalom
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Science, Western Sydney University, 2750, Penrith, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Philip K. Ahring
raw_affiliation_strings: School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 2050, Sydney, NSW, Australia
School of Medical Sciences, Faculty of Medicine and Health, Brain and Mind Centre, The University of Sydney, 200, Sydney, NSW, Australia
raw_author_name: Rikke S. Møller
raw_affiliation_strings: Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 4293, Dianalund, Denmark
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 5230, Odense, Denmark
Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, 520, Odense, Denmark
Department of Epilepsy Genetics and Personalized Medicine, Member of ERN EpiCARE, Danish Epilepsy Center, 493, Dianalund, Denmark