Immunogenicity and safety of a group B Streptococcus vaccine (GBS-AlpN) in pregnant women and their infants: a phase 2, multicentre, observer-blind, randomised, placebo-controlled study
Year: 2025
Type: article
Language: en
Topic: Neonatal and Maternal Infections
Authors and affiliations:
raw_author_name: Paul T Heath
raw_affiliation_strings: St George's Vaccine Institute, Institute for Infection and Immunity, City St George's, University of London, London, UK
raw_author_name: Ntokozo Zuma-Gwala
raw_affiliation_strings: Setshaba Research Centre, Soshanguve, Gauteng, South Africa
raw_author_name: Rikke Bek Helmig
raw_affiliation_strings: Department of Obstetrics and Gynaecology, Aarhus University Hospital, Skejby, Denmark; Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark
raw_author_name: Elizea Horne
raw_affiliation_strings: Wits RHI, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
raw_author_name: Anette Kjærbye-Thygesen
raw_affiliation_strings: Department of Obstetrics and Gynaecology, Copenhagen University Hospital Amager and Hvidovre Hospital, Copenhagen, Denmark
raw_author_name: Mie Korslund Wiinblad Crusell
raw_affiliation_strings: Department of Obstetrics and Gynaecology, Copenhagen University Hospital Amager and Hvidovre Hospital, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
raw_author_name: Maphoshane Nchabeleng
raw_affiliation_strings: Mecru Clinical Research Unit, Sefako Makgatho Health Sciences University, Pretoria, South Africa; National Health Laboratory Service, Dr George Mukhari Academic Microbiology Laboratory, Ga-Rankuwa, Pretoria, South Africa
raw_author_name: Renate Strehlau
raw_affiliation_strings: South African Medical Research Council Vaccines and Infectious Diseases Analytics Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Nkanyezi Research Unit, Department of Paediatrics and Child Health, University of the Witwatersrand, Johannesburg, South Africa
raw_author_name: Mohammed R Khalil
raw_affiliation_strings: Research Unit of Gynaecology and Obstetrics (Kolding), Department of Regional Health Research, Lillebælt Hospital, Vejle, Denmark
raw_author_name: Christine E Jones
raw_affiliation_strings: Faculty of Medicine and Institute for Life Sciences, University of Southampton, Southampton, UK; National Institute for Health and Care Research Southampton Clinical Research Facility and National Institute for Health and Care Research Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK
raw_author_name: Jorne Biccler
raw_affiliation_strings: Sanos, Søborg, Denmark
raw_author_name: Jeannett Dimsits
raw_affiliation_strings: MinervaX, Frederiksberg, Denmark. Electronic address: jeannett.dimsits@dadlnet.dk
MinervaX, Frederiksberg, Denmark. Electronic address: jdi@minervax.com
raw_author_name: Bengt Johansson-Lindbom
raw_affiliation_strings: MinervaX, Frederiksberg, Denmark; Department of Experimental Medical Science, Lund University Cancer Centre, Medicon Village, Lund University, Lund, Sweden
raw_author_name: Per B Fischer
raw_affiliation_strings: MinervaX, Frederiksberg, Denmark
raw_author_name: Lidia Oostvogels
raw_affiliation_strings: MinervaX, Frederiksberg, Denmark
South African Medical Research Council Vaccines and Infectious Diseases Analytics Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
raw_author_name: Shabir A Madhi
raw_affiliation_strings: South African Medical Research Council Vaccines and Infectious Diseases Analytics Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Wits Infectious Diseases and Oncology Research Institute, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
raw_author_name: Louise Monfeldt Schmidt
raw_author_name: Diane Gorm Malberg-Pedersen
raw_author_name: Christina Løngren Karlsen
raw_author_name: Beatriz Morais
raw_author_name: Vanessa Greening
raw_author_name: Emma Eccleston
raw_author_name: Asma Khalil
raw_author_name: Kirsty Le Doare
raw_author_name: Eva Galiza
raw_author_name: Simone Paulson
raw_author_name: Rhea Hampton
raw_author_name: Kate Raney
raw_author_name: Nicki Martin
raw_author_name: Fiona Walbridge
raw_author_name: Monica Corcoles Fernandez
raw_author_name: Emily Cornish
raw_author_name: Laura Sparks
raw_author_name: Rebecca Durham
raw_author_name: Patience Faith Kwedza
raw_author_name: Salome Makaba
raw_author_name: Gcebile Dlamini
raw_author_name: Hamisha Soma-Kasiram
raw_author_name: Matsontso Mathebula
raw_author_name: Dineo Noko
raw_author_name: Ingrid Ramboho
raw_author_name: Nontando Moeketsi
raw_author_name: Mehreen Jalilzadeh Khoie
raw_author_name: Anthonet Koen
raw_author_name: Charmaine Machimana
raw_author_name: Lisa Jose
raw_author_name: Amy Tamblyn
raw_author_name: Carol Taoushanis