Bispecific BAFF-R/BCMA CAR T cells control growth of heterogeneous plasma cells in multiple myeloma
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Agnese Fiori
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany
raw_author_name: Karin Zimmermann
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany
raw_author_name: Anna Li
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer; 13125 Berlin, Germany
raw_author_name: Jörg Westermann
raw_affiliation_strings: Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Virchow Klinikum, 13353 Berlin, Germany
Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Virchow Klinikum; 13353 Berlin, Germany
raw_author_name: Ioannis Anagnostopoulos
raw_affiliation_strings: University of Würzburg, Institute of Pathology, 97080 Würzburg, Germany
University of Würzburg, Institute of Pathology; 97080 Würzburg, Germany
raw_author_name: Lutz Menzel
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany
raw_author_name: Mario Bunse
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer; 13125 Berlin, Germany
raw_author_name: Henry Erdlei
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany
raw_author_name: Jeyan Jayarajan
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer; 13125 Berlin, Germany
raw_author_name: Florian Grünschläger
raw_affiliation_strings: Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH); 69120 Heidelberg, Germany; Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ); 69120 Heidelberg, Germany
raw_author_name: Juan Pablo Ortiz-Aguirre
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany; Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Virchow Klinikum, 13353 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany; Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Virchow Klinikum; 13353 Berlin, Germany
raw_author_name: Simon Haas
raw_affiliation_strings: Berlin Institute of Health (BIH), 10178 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, BIMSB, Berlin, Germany; Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Benjamin Franklin, 12203 Berlin, Germany; Precision Healthcare University Research Institute, Queen Mary University of London, London E1 1HH, UK
Berlin Institute of Health (BIH); 10178 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, BIMSB; Berlin, Germany; Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Benjamin Franklin; 12203 Berlin, Germany; Precision Healthcare University Research Institute, Queen Mary University of London; London E1 1HH, UK
raw_author_name: Uwe-Jens Teßmann
raw_affiliation_strings: Helios Klinik Berlin-Buch, Department of Trauma Surgery, 13125 Berlin, Germany
Helios Klinik Berlin-Buch, Department of Trauma Surgery; 13125 Berlin, Germany
raw_author_name: Jens Freitag
raw_affiliation_strings: Helios Klinik Berlin-Buch, Department of Trauma Surgery, 13125 Berlin, Germany
Helios Klinik Berlin-Buch, Department of Trauma Surgery; 13125 Berlin, Germany
raw_author_name: Andreas Rosenwald
raw_affiliation_strings: University of Würzburg, Institute of Pathology, 97080 Würzburg, Germany
University of Würzburg, Institute of Pathology; 97080 Würzburg, Germany
raw_author_name: Larry Kwak
raw_affiliation_strings: Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA
Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute Beckman Research Institute of City of Hope; Duarte, CA 91010
raw_author_name: Xiuli Wang
raw_affiliation_strings: Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA
Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute Beckman Research Institute of City of Hope; Duarte, CA 91010
raw_author_name: Zhenyuan Dong
raw_affiliation_strings: Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA
Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute Beckman Research Institute of City of Hope; Duarte, CA 91010
raw_author_name: Soungchul Cha
raw_affiliation_strings: Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute, Beckman Research Institute of City of Hope, Duarte, CA 91010, USA
Toni Stephenson Lymphoma Center, Hematologic Malignancies Research Institute Beckman Research Institute of City of Hope; Duarte, CA 91010
raw_author_name: John Reiser
raw_affiliation_strings: Fate Therapeutics, San Diego, CA 92131, USA
Fate Therapeutics; San Diego, CA 92131
raw_author_name: Eigen Peralta
raw_affiliation_strings: Fate Therapeutics, San Diego, CA 92131, USA
Fate Therapeutics; San Diego, CA 92131
raw_author_name: Bahram Valamehr
raw_affiliation_strings: Fate Therapeutics, San Diego, CA 92131, USA
Fate Therapeutics; San Diego, CA 92131
raw_author_name: Jan Krönke
raw_affiliation_strings: Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Benjamin Franklin, 12203 Berlin, Germany
Charité-University Medicine Berlin, Department of Hematology, Oncology and Tumorimmunology, Campus Benjamin Franklin; 12203 Berlin, Germany
raw_author_name: Uta E. Höpken
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer, 13125 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine, Department of Microenvironmental Regulation in Autoimmunity and Cancer; 13125 Berlin, Germany
raw_author_name: Armin Rehm
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology, 13125 Berlin, Germany. Electronic address: arehm@mdc-berlin.de
Max-Delbrück-Center for Molecular Medicine, Department of Translational Tumorimmunology; 13125 Berlin, Germany. Electronic address: arehm@mdc-berlin.de