<i>APOE</i> *4 Risk-Modifying Genes and Drug Targets in Alzheimer’s Disease through Cell-Type Specific Genomic Analyses
Year: 2025
Type: preprint
Language: en
Topic: Alzheimer's disease research and treatments
Authors and affiliations:
raw_author_name: Youjie Zeng
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Noah Cook
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Chenyu Yang
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Sathesh K. Sivasankaran
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Masashi Fujita
raw_affiliation_strings: Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA
raw_author_name: Zachary A. Gardell
raw_affiliation_strings: Department of Neurology, University of California San Francisco, San Francisco, CA, USA
Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA
Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA
raw_author_name: Yann Le Guen
raw_affiliation_strings: Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, CA, 94304, USA
raw_author_name: Daichi Shigemizu
raw_affiliation_strings: Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan
Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
raw_author_name: Kouichi Ozaki
raw_affiliation_strings: Department of Aging Research, Nagoya University Graduate School of Medicine, Nagoya, Japan
Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan
Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
raw_author_name: Takashi Morizono
raw_affiliation_strings: Medical Genome Center, Research Institute, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
raw_author_name: Norikazu Hara
raw_affiliation_strings: Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan
raw_author_name: Akinori Miyashita
raw_affiliation_strings: Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan
raw_author_name: Takeshi Ikeuchi
raw_affiliation_strings: Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan
raw_author_name: Cyril Pottier
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Carlos Cruchaga
raw_affiliation_strings: Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA
raw_author_name: Valerio Napolioni
raw_affiliation_strings: School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, 62032, Italy
raw_author_name: M. Ryan Corces
raw_affiliation_strings: Department of Neurology, University of California San Francisco, San Francisco, CA, USA
Gladstone Institute of Data Science and Biotechnology, Gladstone Institutes, San Francisco, CA, USA
Gladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA, USA
raw_author_name: Vilas Menon
raw_affiliation_strings: Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA
raw_author_name: Michael D. Greicius
raw_affiliation_strings: Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA
raw_author_name: Michael E. Belloy
raw_affiliation_strings: Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA
NeuroGenomics and Informatics Center, Washington University School of Medicine, St. Louis, MO, USA