The Endo-GeneScreen platform identifies drug-like probes that regulate endogenous protein levels within physiological contexts
Year: 2025
Type: article
Language: en
Topic: Genomics and Rare Diseases
Authors and affiliations:
raw_author_name: Preston Samowitz
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA
raw_author_name: Laszlo Radnai
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Thomas Vaissiere
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Sheldon D. Michaelson
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Camilo Rojas
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Ryan Mitchell
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA
raw_author_name: Murat Kilinc
raw_affiliation_strings: Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
Merck & Co, Rahway, NJ, USA
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA
raw_author_name: Austin Edwards
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Justin Shumate
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Richard Hawkins
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Virneliz Fernandez-Vega
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Timothy P. Spicer
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Louis Scampavia
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Theodore Kamenecka
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
raw_author_name: Courtney A. Miller
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA
raw_author_name: Gavin Rumbaugh
raw_affiliation_strings: Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA. gavinrumbaugh@ufl.edu
Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA. gavinrumbaugh@ufl.edu
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA. gavinrumbaugh@ufl.edu
The Skaggs Graduate School of Chemical and Biological Sciences at Scripps Research, Jupiter, FL, USA
Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA
Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA