Prime editing of the β1 adrenoceptor in the brain restores physiological REM sleep in a mouse model of Alzheimer’s disease
Year: 2025
Type: article
Language: en
Topic: Neurobiology and Insect Physiology Research
Authors and affiliations:
raw_author_name: Desirée Böck
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. desiree.boeck@hest.ethz.ch
Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland. desiree.boeck@hest.ethz.ch
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland. desiree.boeck@hest.ethz.ch
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
raw_author_name: Lisa Tidecks
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Maria Wilhelm
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Waleed ElGrawani
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Sian Duss
raw_affiliation_strings: Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Chiara Trevisan
raw_affiliation_strings: Institute of Neuropathology, University of Zurich, Zurich, Switzerland
raw_author_name: Dalila Vena
raw_affiliation_strings: Institute of Neuropathology, University of Zurich, Zurich, Switzerland
raw_author_name: Anna Maria Reuss
raw_affiliation_strings: Institute of Neuropathology, University of Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Lucas Kissling
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Matteo Ranucci
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Mattia Privitera
raw_affiliation_strings: Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Lisa K. Polzer
raw_affiliation_strings: Institute of Chemistry and Biochemistry, Free University of Berlin, Berlin, Germany
Institute of Neuropathology, University of Zurich, Zurich, Switzerland
raw_author_name: Athena E. Economides
raw_affiliation_strings: Institute of Neuropathology, University of Zurich, Zurich, Switzerland
raw_author_name: Eleonora I. Ioannidi
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Raquel Mendes
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Yanik Weber
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Justine Leonardi
raw_affiliation_strings: Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Jonas Mumenthaler
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Elina Villiger
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Romain Goutagny
raw_affiliation_strings: University of Strasbourg, CNRS, LNCA UMR 7364, Strasbourg, France
raw_author_name: Chantal Mathis
raw_affiliation_strings: University of Strasbourg, CNRS, LNCA UMR 7364, Strasbourg, France
raw_author_name: Lukas Schmidheini
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Tanja Rothgangl
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Sharan Janjuha
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Tommaso Patriarchi
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Johannes Bohacek
raw_affiliation_strings: Laboratory of Molecular and Behavioral Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Yaroslav Sych
raw_affiliation_strings: Institute of Cellular and Integrative Neuroscience, CNRS UPR3212, University of Strasbourg, Strasbourg, France
raw_author_name: Adriano Aguzzi
raw_affiliation_strings: Institute of Neuropathology, University of Zurich, Zurich, Switzerland
Neuroscience Center Zurich (ZNZ), University of Zurich and ETH Zurich, Zurich, Switzerland
raw_author_name: Jochen Winterer
raw_affiliation_strings: Laboratory of Systems Neuroscience, Institute for Neuroscience, Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
raw_author_name: Konstantinos Kompotis
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland
raw_author_name: Gerald Schwank
raw_affiliation_strings: Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. schwank@pharma.uzh.ch
Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland