Leveraging large-scale biobanks for therapeutic target discovery
Year: 2025
Type: article
Language: en
Topic: Genetic Associations and Epidemiology
Authors and affiliations:
raw_author_name: Brian R. Ferolito
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.. Electronic address: brian.ferolito@va.gov
raw_author_name: Hesam Dashti
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, 02115, MA, USA.; Broad Institute of MIT and Harvard, 415 Main St., Cambridge, 02142, MA, USA
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Health Data Science Centre, Human Technopole, V.le Rita Levi-Montalcini, 1, Milan, 20157, Italy; Centre for Human Technologies (CHT), Insituto Italiano di Tecnologia, Via Enrico Melen 83, Building B, 7th floor, Genova, 16152, Italy
raw_author_name: Gina M. Peloso
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Ave Crosstown Center, Boston, 02115, MA, USA
raw_author_name: Daniel J. Golden
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, 02115, MA, USA
raw_author_name: Kai Gravel-Pucillo
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, 02115, MA, USA
raw_author_name: Danielle Rasooly
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, 02115, MA, USA
raw_author_name: Andrea R.V.R. Horimoto
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; Division of Aging, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, 02115, MA, USA
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA
raw_author_name: Liam Gaziano
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; BHF Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0BB, UK
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MRC Integrative Epidemiology Unit, Bristol Medical School, Bristol, BS8 1QU, UK
raw_author_name: Ines A. Smit
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European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, CB10 1SD, UK
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European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, CB10 1SD, UK
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Open Targets, Hinxton, CB10 1SD, UK
raw_author_name: Lauren Costa
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA
raw_author_name: Jennifer E. Huffman
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Million Veteran Program (MVP) Coordinating Center, Veterans Affairs Healthcare System, 2 Avenue de Lafayette, Boston, 02111, MA, USA.; VA Palo Alto Healthcare System, Palo Alto, 94304, CA, USA; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA
raw_author_name: Gian Gaetano Tartaglia
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Centre for Human Technologies (CHT), Insituto Italiano di Tecnologia, Via Enrico Melen 83, Building B, 7th floor, Genova, 16152, Italy.; ICREA - Instituci´o Catalana de Recerca I Estudis Avan¸cats, Pg. Llu´is Companys 23, Barcelona, 08010, Spain
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Centre for Human Technologies (CHT), Insituto Italiano di Tecnologia, Via Enrico Melen 83, Building B, 7th floor, Genova, 16152, Italy.; Universit`a degli Studi di Genova, via Balbi 5, Genova, 16126, Italy
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Centre for Human Technologies (CHT), Insituto Italiano di Tecnologia, Via Enrico Melen 83, Building B, 7th floor, Genova, 16152, Italy
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European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, CB10 1SD, UK
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European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, CB10 1SD, UK
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BHF Cardiovascular Epidemiology Unit, University of Cambridge, Cambridge, CB2 0BB, UK; NIHR Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, CB2 0BB, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, CB2 0BB, UK.; British Heart Foundation Centre of Research Excellence, School of Clinical Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, CB2 0BB, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, CB2 0BB, UK
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