Identification of Novel Susceptibility Genes for Early-Onset Colorectal Cancer Through Germline Rare Variant Burden Testing
Year: 2025
Type: article
Language: en
Topic: Genetic factors in colorectal cancer
Authors and affiliations:
raw_author_name: Ruocen Song
raw_affiliation_strings: Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
raw_author_name: Reger R. Mikaeel
raw_affiliation_strings: Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA
raw_author_name: Zhongping He
raw_affiliation_strings: Department of Biostatistics, University of Florida, Gainesville, FL 32611, USA
raw_author_name: Mehgan Horsnell
raw_affiliation_strings: Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
raw_author_name: Wendy Uylaki
raw_affiliation_strings: Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
raw_author_name: Weimin Meng
raw_affiliation_strings: Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL 32611, USA
raw_author_name: Nicola K. Poplawski
raw_affiliation_strings: Adelaide Medical School, University of Adelaide, Adelaide, SA 5000, Australia
Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, SA 5000, Australia
raw_author_name: Bernd Wollnik
raw_affiliation_strings: Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany
raw_author_name: Yun Li
raw_affiliation_strings: Institute of Human Genetics, University Medical Center Göttingen, 37075 Göttingen, Germany
raw_author_name: Jinghua Feng
raw_affiliation_strings: Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5001, Australia
Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia
raw_author_name: Hamish S. Scott
raw_affiliation_strings: Centre for Cancer Biology, SA Pathology and University of South Australia, Adelaide, SA 5001, Australia
Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, SA 5000, Australia
Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia
raw_author_name: Yufeng Shen
raw_affiliation_strings: Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
raw_author_name: Chen Wang
raw_affiliation_strings: Department of Biostatistics, Columbia University Irving Medical Center, New York, NY 10032, USA
raw_author_name: Rui Yin
raw_affiliation_strings: Department of Health Outcomes and Biomedical Informatics, University of Florida, Gainesville, FL 32611, USA
raw_author_name: Yousong Ding
raw_affiliation_strings: Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, University of Florida, Gainesville, FL 32611, USA
raw_author_name: Xavier Llor
raw_affiliation_strings: Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06520, USA
raw_author_name: Wendy K. Chung
raw_affiliation_strings: Department of Pediatrics, Boston Children’s Hospital, Boston, MA 02115, USA
Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Eric Smith
raw_affiliation_strings: Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia
raw_author_name: Timothy J. Price
raw_affiliation_strings: Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia
raw_author_name: Joanne P. Young
raw_affiliation_strings: Department of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville, SA 5011, Australia
Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5000, Australia
raw_author_name: Xiao Fan
raw_affiliation_strings: Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA
University of Florida Health Cancer Center, Gainesville, FL 32610, USA