Plasma Proteomics in Acute Heart Failure: Survival-Associated Protein Signatures and 90-Day Trajectories
Year: 2025
Type: article
Topic: Advanced Proteomics Techniques and Applications
Authors and affiliations:
raw_author_name: Alexandra M Chitroceanu
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Pauline Fahjen
raw_affiliation_strings: Freie Universität Berlin, Department of Biology, Chemistry and Pharmacy, Königin-Luise- Straße 28-30, 14195 Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
Proteomics Platform, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Daniel Schulze
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Veronika Zach
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Lina Alasfar
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
raw_author_name: Matthias Ziehm
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Marieluise Kirchner
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Sylvia Niquet
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Jan-Niklas Dahmen
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Carlos Plappert
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Lucie Kretzler
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Andreas Kind
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Daniela Zurkan
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Rafaela Maria Pinto
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
raw_author_name: Edwardo Reynolds
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Tobias D Trippel
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
raw_author_name: Sofia Forslund
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Ulrike Grittner
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Knut Mai
raw_affiliation_strings: DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Department of Endocrinology and Metabolism, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, European Reference Network on Rare Endocrine Diseases (ENDO-ERN), Berlin, Germany
Department of Human Nutrition, German Institute of Human Nutrition Potsdam- Rehbrücke, Nuthetal, Germany
German Center for Diabetes Research, München-Neuherberg, Germany
Max Rubner Center for Cardiovascular Metabolic Renal Research, Charité-Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Michael Gotthardt
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
Translational Cardiology and Functional Genomics, Max Delbrück Center for Molecular Medicine, Berlin, Germany
raw_author_name: Gabriele G Schiattarella
raw_affiliation_strings: DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Charité - Universitätsmedizin Berlin, Berlin, Germany
Translational Approaches in Heart Failure and Cardiometabolic Disease, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany
raw_author_name: Ulrich Kintscher
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Institute of Pharmacology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
Max Rubner Center for Cardiovascular Metabolic Renal Research, Charité-Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Michael Ahmadi
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
raw_author_name: Leif-Hendrik Boldt
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Nikolaus Buchmann
raw_affiliation_strings: Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
raw_author_name: Kai-Uwe Eckardt
raw_affiliation_strings: Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Matthias Endres
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Center for Stroke Research (CSB), Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
Department of Neurology with experimental Neurology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Holger Gerhardt
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Norbert Hübner
raw_affiliation_strings: Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Jil Kollmus-Heege
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Ulf Landmesser
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Charité - Universitätsmedizin Berlin, Berlin, Germany
raw_author_name: Dominik N Müller
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Experimental and Clinical Research Center, a cooperation of Charité-Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Christian H Nolte
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Center for Stroke Research (CSB), Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Department of Neurology with experimental Neurology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Sophie K Piper
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Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
raw_author_name: Simrit Rattan
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Ira Rohrpasser-Napierkowski
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raw_author_name: Katharina Schönrath
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raw_author_name: Jeanette Schulz-Menger
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DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Oliver Schweizerhof
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Institute of Biometry and Clinical Epidemiology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Tobias Pischon
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Biobank Technology Platform, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Burkert Pieske
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raw_author_name: Joachim Weber
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Center for Stroke Research (CSB), Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Department of Neurology with experimental Neurology, Charité- Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
Max Rubner Center for Cardiovascular Metabolic Renal Research, Charité-Universitätsmedizin Berlin, corporate member of the Freie Universität Berlin and Humboldt-Universität Berlin, Berlin, Germany
raw_author_name: Philipp Mertins
raw_affiliation_strings: Berlin Institute of Health at Charité – Universitätsmedizin Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
Proteomics Platform, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany
raw_author_name: Frank Edelmann
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Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany
Deutsches Herzzentrum der Charité (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Virchow Klinikum, Berlin, Germany