Effects of zibotentan and dapagliflozin combined in patients with compensated cirrhosis: A randomized placebo‐controlled exploratory study
Year: 2025
Type: article
Language: en
Topic: Liver Disease and Transplantation
Authors and affiliations:
raw_author_name: Juan Carlos Garcia‐Pagan
raw_affiliation_strings: Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clínic, Institut de Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). CIBEREHD (Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas). Health Care Provider of the European Reference Network on Rare Liver Disorders (ERN RARE‐Liver). Departament de Medicina i Ciències de la Salut. Universitat de Barcelona  Barcelona Spain
raw_author_name: Lise Lotte Gluud
raw_affiliation_strings: Gastro Unit Copenhagen University Hospital Hvidovre and Department of Clinical Medicine, University of Copenhagen  Copenhagen Denmark
Gastro Unit, Copenhagen University Hospital Hvidovre and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
raw_author_name: Mattias Mandorfer
raw_affiliation_strings: Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Medicine III Medical University of Vienna  Vienna Austria
Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria
raw_author_name: Jörn M. Schattenberg
raw_affiliation_strings: Department of Internal Medicine II Saarland University Medical Center  Homburg Germany
Department of Internal Medicine II, Saarland University Medical Center, Homburg, Germany
raw_author_name: Andrea De Gottardi
raw_affiliation_strings: Gastroenterology and Hepatology, Luzerner Kantonsspital, Luzern  Switzerland
Gastroenterology and Hepatology, Luzerner Kantonsspital, Luzern, Switzerland
raw_author_name: Annalisa Berzigotti
raw_affiliation_strings: Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital University of Bern  Bern Switzerland
Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
raw_author_name: José Ignacio Fortea
raw_affiliation_strings: Gastroenterology and Hepatology Department, Clinical and Translational Research in Digestive Diseases, Valdecilla Research Institute (IDIVAL) Marqués de Valdecilla University Hospital  Santander Spain
raw_author_name: Agustin Albillos Martínez
raw_affiliation_strings: Dept of Gastroenterology, Hospital Universitario Ramon y Cajal, IRYCIS, CIBEREHD University of Alcala  Madrid Spain
Dept of Gastroenterology, Hospital Universitario Ramon y Cajal, IRYCIS, CIBEREHD, University of Alcala, Madrid, Spain
raw_author_name: Edilmar Alvarado‐Tapias
raw_affiliation_strings: Department of Gastroenterology Hospital Santa Creu i Sant Pau, Barcelona, Spain. Centre for Biomedical Research in Liver and Digestive Diseases Network (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain. Universitat Autònoma de Barcelona (UAB), Departament de Medicina UAB  Barcelona Spain
raw_author_name: Marco Berning
raw_affiliation_strings: Department of Medicine I University Hospital Dresden, Technische Universität Dresden (TU Dresden)  Dresden Germany
raw_author_name: Pawel Petryszyn
raw_affiliation_strings: Department of Clinical Pharmacology Wroclaw Medical University  Wroclaw Poland
Late‐stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca  Warsaw Poland
Late-stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca, Warsaw, Poland
raw_author_name: Emilia Henricson
raw_affiliation_strings: Biopharmaceutical Clinical Operations, Cardiovascular, Renal and Metabolic, AstraZeneca  Gothenburg Sweden
Biopharmaceutical Clinical Operations, Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden
raw_author_name: Niklas Berglind
raw_affiliation_strings: Late‐stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca  Gothenburg Sweden
Late-stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden
raw_author_name: Min Lin
raw_affiliation_strings: Late‐stage Development, Biometrics, Cardiovascular, Renal and Metabolic, AstraZeneca  Gaithersburg Maryland USA
Late-stage Development, Biometrics, Cardiovascular, Renal and Metabolic, AstraZeneca, Gaithersburg, Maryland, USA
raw_author_name: Kevin Persson
raw_affiliation_strings: Late‐stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca  Gothenburg Sweden
Late-stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden
raw_author_name: Anne‐Kristina Mercier
raw_affiliation_strings: Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&amp;D, AstraZeneca  Gothenburg Sweden
Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, R&amp;D, AstraZeneca Gothenburg Sweden
raw_author_name: Phil Ambery
raw_affiliation_strings: Late‐stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca  Gothenburg Sweden
Late-stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden
raw_author_name: Jaime Bosch
raw_affiliation_strings: Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital University of Bern  Bern Switzerland
Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland
raw_author_name: Jan Oscarsson
raw_affiliation_strings: Late‐stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca  Gothenburg Sweden
Late-stage Clinical Development, Cardiovascular, Renal and Metabolic, AstraZeneca, Gothenburg, Sweden
raw_author_name: Don C. Rockey
raw_affiliation_strings: Medical University of South Carolina College of Medicine  South Carolina USA
Medical University of South Carolina, College of Medicine, South Carolina, USA