Discovery of ART5537: A Potent and Selective Small-Molecule Probe for EXO1
Year: 2025
Type: article
Language: en
Topic: DNA Repair Mechanisms
Authors and affiliations:
raw_author_name: Sam E. Mann
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Owen A. Davis
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Jörg Bomke
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Irina Cornaciu
raw_affiliation_strings: ALPX, 71 Avenue des Martyrs, 38000 Grenoble, France
raw_author_name: Elias Elinati
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Bruce Follows
raw_affiliation_strings: EMD Serono Research & Development Institute
EMD Serono Research & Development Institute, Billerica, Massachusetts 018-21-3936, United States
raw_author_name: Alessandro Galbiati
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Lerin Geo
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Diego Grande
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Catherine Jorand-Lebrun
raw_affiliation_strings: EMD Serono Research & Development Institute
EMD Serono Research & Development Institute, Billerica, Massachusetts 018-21-3936, United States
raw_author_name: Claudio A. Lademann
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Julien Lefranc
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Birgitta Leuthner
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Bethany Mason
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Claire L. McWhirter
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Djordje Musil
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Ulrich Pehl
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Carl Petersson
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Andrea Pica
raw_affiliation_strings: ALPX, 71 Avenue des Martyrs, 38000 Grenoble, France
raw_author_name: Maria Filipa Pinto
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Eeson Rajendra
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Christin Rakers
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Ana Toste Rêgo
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Helen M. R. Robinson
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Daniel Schwarz
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Graeme C. M. Smith
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Fiona J. Sorrell
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Frank T. Zenke
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany
raw_author_name: Robert A. Heald
raw_affiliation_strings: Artios Pharma Ltd., B940, Babraham Research Campus, Cambridge CB22 3FH, U.K
raw_author_name: Lars T. Burgdorf
raw_affiliation_strings: Merck Healthcare KGaA
Merck Healthcare KGaA, 64293 Darmstadt, Germany