Effective therapeutic targeting of <i>CTNNB1</i> ‐mutant hepatoblastoma with <scp>WNTinib</scp>
Year: 2025
Type: article
Language: en
Topic: Wnt/β-catenin signaling in development and cancer
Authors and affiliations:
raw_author_name: Ugne Balaseviciute
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Júlia Huguet‐Pradell
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Jordi Abril‐Fornaguera
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Albert Gris‐Oliver
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
raw_author_name: Alex Rialdi
raw_affiliation_strings: Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Elisa Fernández‐Martínez
raw_affiliation_strings: Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Carla Montironi
raw_affiliation_strings: Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Pathology Department and Molecular Biology Core Hospital Clínic of Barcelona  Spain
raw_author_name: Vanessa Del Pozo
raw_affiliation_strings: Greehey Children's Cancer Research Institute University of Texas Health Science Center  San Antonio TX USA
Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX, USA
raw_author_name: Peter Houghton
raw_affiliation_strings: Greehey Children's Cancer Research Institute University of Texas Health Science Center  San Antonio TX USA
Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, TX, USA
raw_author_name: Laura Zanatto
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Universitat de Barcelona  Spain
raw_author_name: Agavni Mesropian
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Ieva Keraite
raw_affiliation_strings: Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Swan Thung
raw_affiliation_strings: Department of Pathology ISMMS  New York NY USA
Department of Pathology, ISMMS, New York, NY, USA
raw_author_name: Carolina Armengol
raw_affiliation_strings: Childhood Liver Oncology Group (c‐LOG) Health Sciences Research Institute Germans Trias i Pujol (IGTP)  Badalona Spain
Liver and Digestive Diseases Networking Biomedical Research Centre (CIBEREHD)  Madrid Spain
Childhood Liver Oncology Group (c-LOG), Health Sciences Research Institute Germans Trias i Pujol (IGTP), Badalona, Spain
Liver and Digestive Diseases Networking Biomedical Research Centre (CIBEREHD), Madrid, Spain
raw_author_name: Pau Sancho‐Bru
raw_affiliation_strings: Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Universitat de Barcelona  Spain
raw_author_name: Ernesto Guccione
raw_affiliation_strings: Bioinformatics for Next Generation Sequencing Shared Resource Facility Icahn School of Medicine at Mount Sinai  New York NY USA
Center for OncoGenomics and Innovative Therapeutics Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Center for Therapeutics Discovery, Department of Oncological Sciences and Pharmacological Sciences Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
The Precision Immunology Institute Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
raw_author_name: Roser Pinyol
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
raw_author_name: Josep M. Llovet
raw_affiliation_strings: Facultat de Medicina i Ciències de la Salut Universitat de Barcelona  Catalonia Spain
Institució Catalana de Recerca i Estudis Avançats  Barcelona Catalonia Spain
Liver Cancer Translational Research Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic Universitat de Barcelona  Catalonia Spain
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology) Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai  New York NY USA
Mount Sinai Liver Cancer Program (Divisions of Liver Diseases, Department of Hematology/Oncology, Department of Medicine, Department of Pathology), Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA