Deep learning reveals endogenous sterols as allosteric modulators of the GPCR–Gα interface
Year: 2025
Type: article
Language: en
Topic: Receptor Mechanisms and Signaling
Authors and affiliations:
raw_author_name: Sanjay Kumar Mohanty
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Aayushi Mittal
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Namra Farooqi
raw_affiliation_strings: Academy of Scientific and Innovative Research (AcSIR)
CSIR-Institute of Microbial Technology, Sector-39A
raw_author_name: Aakash Gaur
raw_affiliation_strings: Academy of Scientific and Innovative Research (AcSIR)
Pharmacology Division, CSIR-Central Drug Research Institute
raw_author_name: Subhadeep Duari
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Saveena Solanki
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Anmol Kumar Sharma
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Sakshi Arora
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Suvendu Kumar
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Vishakha Gautam
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Nilesh Kumar Dixit
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Karthika Subramanian
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Tarini Shankar Ghosh
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Debarka Sengupta
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
Infosys Centre for AI, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Shashi Kumar Gupta
raw_affiliation_strings: Academy of Scientific and Innovative Research (AcSIR)
Pharmacology Division, CSIR-Central Drug Research Institute
raw_author_name: Arul Natarajan Murugan
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
raw_author_name: Deepak Sharma
raw_affiliation_strings: Academy of Scientific and Innovative Research (AcSIR)
CSIR-Institute of Microbial Technology, Sector-39A
raw_author_name: Gaurav Ahuja
raw_affiliation_strings: Department of Computational Biology, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)
Infosys Centre for AI, Indraprastha Institute of Information Technology-Delhi (IIIT-Delhi)