Efficacy and safety of Janus kinase 1/2 inhibitor KL130008 in active rheumatoid arthritis: a randomized, double-blind, placebo-controlled phase II trial
Year: 2025
Type: article
Language: en
Topic: Rheumatoid Arthritis Research and Therapies
Authors and affiliations:
raw_author_name: Yue Cheng
raw_affiliation_strings: Clinical Trial Centerand, National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs , West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610041, Sichuan, China
raw_author_name: Honghu Tang
raw_affiliation_strings: Department of Rheumatology and Immunology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China
raw_author_name: Yufeng Qing
raw_affiliation_strings: Department of Rheumatology and Immunology, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China
raw_author_name: Yuan Liu
raw_affiliation_strings: Department of Rheumatology and Immunology, Liuzhou People's Hospital, Liuzhou, Guangxi, China
Department of Rheumatology and Immunology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China. yi2006liu@163.com
raw_author_name: Lei Yang
raw_affiliation_strings: Department of Rheumatology and Immunology, Zhengzhou Central Hospital, Zhengzhou, Henan, China
raw_author_name: Wantai Dang
raw_affiliation_strings: Department of Rheumatology and Immunology, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China
raw_author_name: Jing Yu
raw_affiliation_strings: Department of Rheumatology and Immunology, The Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China
raw_author_name: Rongbin Li
raw_affiliation_strings: Department of Rheumatology and Immunology, Qiqihar First Hospital, Qiqihar, Heilongjiang, China
raw_author_name: Huaxiang Liu
raw_affiliation_strings: Department of Rheumatology and Immunology, Qilu Hospital of Shandong University, Jinan, Shandong, China
raw_author_name: Zhenyu Jiang
raw_affiliation_strings: Department of Rheumatology and Immunology, The First Hospital of Jilin University, Changchun, Jilin, China
raw_author_name: Hongsheng Sun
raw_affiliation_strings: Department of Rheumatology and Immunology, Shandong Provincial Hospital, Jinan, Shandong, China
raw_author_name: Songlou Yin
raw_affiliation_strings: Department of Rheumatology and Immunology, Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu, China
raw_author_name: Jianzhao Cheng
raw_affiliation_strings: Department of Rheumatology and Immunology, Xiangtan Central Hospital, Xiangtan, Hunan, China
raw_author_name: Zhijun Li
raw_affiliation_strings: Department of Rheumatology and Immunology, The First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China
raw_author_name: Wenqiang Fan
raw_affiliation_strings: Department of Rheumatology and Immunology, Xinxiang Central Hospital, Xinxiang, Henan, China
raw_author_name: Hong Zhang
raw_affiliation_strings: Department of Rheumatology and Immunology, The First People's Hospital of Yunnan Province, Kunming, Yunnan, China
raw_author_name: Hongwei Du
raw_affiliation_strings: Department of Rheumatology and Immunology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China
raw_author_name: Zili Fu
raw_affiliation_strings: Department of Rheumatology and Immunology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
raw_author_name: Xinmei Ma
raw_affiliation_strings: Department of Rheumatology and Immunology, Zaozhuang Municipal Hospital, Zaozhuang, Shandong, China
raw_author_name: Jian Wu
raw_affiliation_strings: Department of Rheumatology and Immunology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
raw_author_name: Lihua Duan
raw_affiliation_strings: Department of Rheumatology and Immunology, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi, China
raw_author_name: Rong Zhang
raw_affiliation_strings: Department of Rheumatology and Immunology, The First Hospital of China Medical University, Shenyang, Liaoning, China
raw_author_name: Jinying Lin
raw_affiliation_strings: Department of Rheumatology and Immunology, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China
raw_author_name: Zhanyun Da
raw_affiliation_strings: Department of Rheumatology and Immunology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China
raw_author_name: Wei Wei
raw_affiliation_strings: Department of Rheumatology and Immunology, Tianjin Medical University General Hospital, Tianjin, China
raw_author_name: Qianxun Zhai
raw_affiliation_strings: Department of Rheumatology and Immunology, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, China
raw_author_name: Bingjie Wu
raw_affiliation_strings: Clinical Research Center, Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., Chengdu, Sichuan, China
raw_author_name: Xiaowei Yi
raw_affiliation_strings: Clinical Research Center, Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., Chengdu, Sichuan, China
raw_author_name: Xiaoping Jin
raw_affiliation_strings: Clinical Research Center, Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., Chengdu, Sichuan, China
raw_author_name: Junyou Ge
raw_affiliation_strings: Clinical Research Center, Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd., Chengdu, Sichuan, China
National Engineering Research Center of Targeted Biologics, Chengdu, Sichuan, China
raw_author_name: Ping Feng
raw_affiliation_strings: Clinical Trial Centerand, National Medical Products Administration Key Laboratory for Clinical Research and Evaluation of Innovative Drugs , West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, 610041, Sichuan, China. fengping@wchscu.cn
raw_author_name: Yi Liu
raw_affiliation_strings: Department of Rheumatology and Immunology, Liuzhou People's Hospital, Liuzhou, Guangxi, China
Department of Rheumatology and Immunology, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, China. yi2006liu@163.com