Phase Separation Contributes to Pathogenicity for Nonsense Mediated Decay-Escaping Variant Alleles
Year: 2025
Type: article
Topic: RNA Research and Splicing
Authors and affiliations:
raw_author_name: Jiaoyang Xu
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: Jacob Schmidt
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: Tugce Bozkurt-Yozgatli
raw_affiliation_strings: Department of Biostatistics and Bioinformatics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
raw_author_name: Iman Egab
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: Luisa Mestroni
raw_affiliation_strings: Adult Medical Genetics Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
raw_author_name: Matthew Taylor
raw_affiliation_strings: Adult Medical Genetics Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
raw_author_name: Jennifer E. Posey
raw_affiliation_strings: Department of Pediatrics, Columbia University Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY; Department of Medicine, Columbia University, New York, NY
Department of Medicine, Columbia University, New York, NY
raw_author_name: Richard A. Gibbs
raw_affiliation_strings: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, 77030, USA
raw_author_name: Eric Boerwinkle
raw_affiliation_strings: The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Houston, TX
raw_author_name: Paul de Vries
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: Alanna Morrison
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: S. Stephen Yi
raw_affiliation_strings: Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA
Dan L Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, TX 77030, USA
Department of Neurosurgery, Baylor College of Medicine, Temple, TX 76508, USA
raw_author_name: Chad A. Shaw
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
raw_author_name: Claudia M.B. Carvalho
raw_affiliation_strings: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA
Pacific Northwest Research Institute, Seattle, WA, USA
raw_author_name: James R. Lupski
raw_affiliation_strings: Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA
Department of Pediatrics, Baylor College of Medicine, Houston, TX, 77030, USA
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, 77030, USA
Texas Children’s Hospital, Houston, TX, 77303, USA
Texas Children's Hospital, Houston, TX, 77303, USA
raw_author_name: Sujatha Jagannathan
raw_affiliation_strings: Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
RNA Bioscience Initiative, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
raw_author_name: Emel Timucin
raw_affiliation_strings: Gebze Technical University, Dept. Molecular Biology&Genetics, Faculty of Science, Gebze 41400 Kocaeli Turkey
raw_author_name: Zeynep Coban-Akdemir
raw_affiliation_strings: Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA