Pre-existing and early cellular immune factors correlate with functionally complete protection against primary controlled human SARS-CoV-2 infection
Year: 2025
Type: article
Language: en
Topic: COVID-19 Clinical Research Studies
Authors and affiliations:
raw_author_name: Helen R. Wagstaffe
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Ryan S. Thwaites
raw_affiliation_strings: National Heart and Lung Institute, Imperial College London, London, UK
raw_author_name: Jasmin K. Sidhu
raw_affiliation_strings: National Heart and Lung Institute, Imperial College London, London, UK
raw_author_name: Rik G. H. Lindeboom
raw_affiliation_strings: The Netherlands Cancer Institute, Amsterdam, the Netherlands
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK
raw_author_name: Lorenz Kretschmer
raw_affiliation_strings: Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK
raw_author_name: Kaylee B. Worlock
raw_affiliation_strings: UCL Respiratory, Division of Medicine, University College London, London, UK
raw_author_name: Lisa M. Dratva
raw_affiliation_strings: Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK
raw_author_name: Ao Huang
raw_affiliation_strings: Center for Systems and Engineering Immunology (CSEI) and Department of Immunobiology, Yale University, New Haven, CT, USA
Program in Computational Biology and Biomedical Informatics, Yale University, New Haven, CT, USA
raw_author_name: Stephanie Ascough
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Loukas Papargyris
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Richard McKendry
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Ashley M. Collins
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Jiayun Xu
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Nana-Marie Lemm
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK
raw_author_name: Ben Killingley
raw_affiliation_strings: Department of Infectious Diseases, University College London Hospital, London, UK
raw_author_name: Mariya Kalinova
raw_affiliation_strings: hVIVO Services Ltd., London, UK
raw_author_name: Alex Mann
raw_affiliation_strings: hVIVO Services Ltd., London, UK
raw_author_name: Andrew Catchpole
raw_affiliation_strings: hVIVO Services Ltd., London, UK
raw_author_name: Leo Swadling
raw_affiliation_strings: Division of Infection and Immunity, University College London, London, UK
raw_author_name: John S. Tsang
raw_affiliation_strings: Center for Systems and Engineering Immunology (CSEI) and Department of Immunobiology, Yale University, New Haven, CT, USA
Department of Biomedical Engineering, Yale University, New Haven, CT, USA
Program in Computational Biology and Biomedical Informatics, Yale University, New Haven, CT, USA
raw_author_name: Mala K. Maini
raw_affiliation_strings: Division of Infection and Immunity, University College London, London, UK
raw_author_name: Mahdad Noursadeghi
raw_affiliation_strings: Division of Infection and Immunity, University College London, London, UK
raw_author_name: Marko Z. Nikolić
raw_affiliation_strings: UCL Respiratory, Division of Medicine, University College London, London, UK
raw_author_name: Sarah A. Teichmann
raw_affiliation_strings: Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
The Netherlands Cancer Institute, Amsterdam, the Netherlands
raw_author_name: Peter J. M. Openshaw
raw_affiliation_strings: National Heart and Lung Institute, Imperial College London, London, UK
raw_author_name: Christopher Chiu
raw_affiliation_strings: Department of Infectious Disease, Imperial College London, London, UK. c.chiu@imperial.ac.uk
Department of Infectious Disease, Imperial College London, London, UK