Mitochondrial Integrated Stress Response Activation Creates a Therapeutic Vulnerability to MCL-1 Inhibition in Acute Myeloid Leukemia
Year: 2025
Type: article
Topic: PI3K/AKT/mTOR signaling in cancer
Authors and affiliations:
raw_author_name: Lauren Brakefield-Laird
raw_affiliation_strings: Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Amit Budhraja
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Peter M. Hall
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
The Center for Advanced Genome Engineering, St Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Dixie Brewington
raw_affiliation_strings: Preclinical Therapeutics Program, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Jamila Moore
raw_affiliation_strings: Preclinical Therapeutics Program, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Josi Lott
raw_affiliation_strings: Center of Excellence for Leukemia Studies St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Yonghui Ni
raw_affiliation_strings: Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Dennis Voronin
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
St. Jude Graduate School of Biomedical Sciences, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Oliver Grant-Chapman
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
St. Jude Graduate School of Biomedical Sciences, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Tresor Mukiza
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Tristen Wright
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
St. Jude Graduate School of Biomedical Sciences, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Yong-Dong Wang
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Sandi Radko-Juettner
raw_affiliation_strings: Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Shondra M. Pruett-Miller
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
The Center for Advanced Genome Engineering, St Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Stanley Pounds
raw_affiliation_strings: Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Peter Vogel
raw_affiliation_strings: Comparative Pathology Core, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA
raw_author_name: Joseph T. Opferman
raw_affiliation_strings: Department of Cell and Molecular Biology, St. Jude Children’s Research Hospital, Memphis, TN, 38105 USA