Methylome-wide association studies and epigenetic biomarker development for 133 mass spectrometry-assessed circulating proteins in 14,671 Generation Scotland participants
Year: 2025
Type: article
Language: en
Topic: Epigenetics and DNA Methylation
Authors and affiliations:
raw_author_name: Josephine A. Robertson
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Jakub Bajzik
raw_affiliation_strings: Institute of Science and Technology, Vienna, Austria
raw_author_name: Spyros Vernardis
raw_affiliation_strings: Eliptica Limited, The London Cancer Hub, Cotswold Road, Sutton, London, UK
Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Aleksandra D. Chybowska
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Daniel L. McCartney
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Arturas Grauslys
raw_affiliation_strings: Eliptica Limited, The London Cancer Hub, Cotswold Road, Sutton, London, UK
raw_author_name: Jure Mur
raw_affiliation_strings: Alzheimer Scotland Dementia Research Centre, Department of Psychology, University of Edinburgh, Edinburgh, UK
Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Hannah M. Smith
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Archie Campbell
raw_affiliation_strings: Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK
Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Camilla Drake
raw_affiliation_strings: MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Hannah Grant
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Jamie Pearce
raw_affiliation_strings: Centre for Research on Environment, Society and Health, School of Geosciences, University of Edinburgh, Edinburgh, UK
raw_author_name: Tom C. Russ
raw_affiliation_strings: Alzheimer Scotland Dementia Research Centre, Department of Psychology, University of Edinburgh, Edinburgh, UK
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
raw_author_name: Poppy Adkin
raw_affiliation_strings: Medical Research Council Clinical Trials Unit, University College London, London, UK
Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Matthew White
raw_affiliation_strings: Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Charles Brigden
raw_affiliation_strings: Eliptica Limited, The London Cancer Hub, Cotswold Road, Sutton, London, UK
raw_author_name: Christoph B. Messner
raw_affiliation_strings: Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
Precision Proteomics Center, Swiss Institute of Allergy and Asthma Research, University of Zurich, Zurich, Switzerland
raw_author_name: David J. Porteous
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Caroline Hayward
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK
raw_author_name: Simon R. Cox
raw_affiliation_strings: Department of Psychology, The Lothian Birth Cohorts, University of Edinburgh, Edinburgh, UK
raw_author_name: Aleksej Zelezniak
raw_affiliation_strings: Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, Gothenburg, SE-412 96, Sweden
Eliptica Limited, The London Cancer Hub, Cotswold Road, Sutton, London, UK
Institute of Biotechnology, Life Sciences Centre, Vilnius University, Sauletekio al. 7, Vilnius, LT10257, Lithuania
Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
Randall Centre for Cell & Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London, SE1 1UL, UK
raw_author_name: Markus Ralser
raw_affiliation_strings: Department of Biochemistry, Charité Universitätsmedizin Berlin, Berlin, Germany
Eliptica Limited, The London Cancer Hub, Cotswold Road, Sutton, London, UK
Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Matthew R. Robinson
raw_affiliation_strings: Institute of Science and Technology, Vienna, Austria
raw_author_name: Riccardo E. Marioni
raw_affiliation_strings: Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. riccardo.marioni@ed.ac.uk
Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK