PLK1 or WEE1 inhibition targets homologous recombination repair proficiency in BRCA1/2 wild-type high-grade serous ovarian cancer
Year: 2025
Type: article
Language: en
Topic: DNA Repair Mechanisms
Authors and affiliations:
raw_author_name: Qian Xi
raw_affiliation_strings: Department of Gynecological Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China
Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Akiko Kunita
raw_affiliation_strings: Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. kunita@m.u-tokyo.ac.jp
Next-Generation Precision Medicine Development Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. kunita@m.u-tokyo.ac.jp
Next-Generation Precision Medicine Development Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Miho Ogawa
raw_affiliation_strings: Next-Generation Precision Medicine Development Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Masanori Kawakami
raw_affiliation_strings: Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Mirei Ka
raw_affiliation_strings: Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Saeko Nagai
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Anh Quynh Duong
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Ayumi Taguchi
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Kousuke Watanabe
raw_affiliation_strings: Next-Generation Precision Medicine Development Laboratory, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Tomohiko Fukuda
raw_affiliation_strings: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
raw_author_name: Kenbun Sone
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Aya Shinozaki-Ushiku
raw_affiliation_strings: Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Tetsuo Ushiku
raw_affiliation_strings: Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Yasushi Hirota
raw_affiliation_strings: Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Hidenori Kage
raw_affiliation_strings: Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Kazuhiro Katayama
raw_affiliation_strings: Laboratory of Molecular Targeted Therapeutics, School of Pharmacy, Nihon University, Chiba, Japan
raw_author_name: Katsutoshi Oda
raw_affiliation_strings: Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. odak@g.ecc.u-tokyo.ac.jp
Division of Integrative Genomics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan