Monitoring rapid degradation of NANOG reveals UTP15 maintains pluripotency by regulating nascent transcripts
Year: 2025
Type: article
Language: en
Topic: Pluripotent Stem Cells Research
Authors and affiliations:
raw_author_name: Mingqiang Deng
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
Key Laboratory of Biological Targeting Diagnosis, Therapy and Rehabilitation of Guangdong Higher Education Institutes, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
raw_author_name: Dongmei He
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Xiwei Wang
raw_affiliation_strings: Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China
raw_author_name: Yuting Yuan
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, China
Peninsula Cancer Research Center, Binzhou Medical University, 346 Guanhai Road, Yantai, Shandong, China
raw_author_name: Lishen Wang
raw_affiliation_strings: Biomedical Science College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China
raw_author_name: Yanlin Hou
raw_affiliation_strings: Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China
raw_author_name: Qiuyue Zhu
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Chuanman Zhou
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Zhibiao Mai
raw_affiliation_strings: Centre for Regenerative Medicine and Health, Hong Kong Institute of Science and Innovation, Chinese Academy of Sciences, Hong Kong, SAR, China
raw_author_name: Yulong Zhang
raw_affiliation_strings: State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Zhengwen Nie
raw_affiliation_strings: Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China
raw_author_name: Yuling Song
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Qiongfang Wu
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Luyao Pan
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Bei Dong
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Zhi Xiong
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Duo Li
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Dongjun Liu
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
raw_author_name: Jinxin Xu
raw_affiliation_strings: China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Dajiang Qin
raw_affiliation_strings: Bioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China
Centre for Regenerative Medicine and Health, Hong Kong Institute of Science and Innovation, Chinese Academy of Sciences, Hong Kong, SAR, China
Guangdong Engineering Research Center of Early Clinical Trials of Biotechnology Drugs, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
Guangdong Engineering Technology Research Center of Biological Targeting Diagnosis, Therapy and Rehabilitation, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
Key Laboratory of Biological Targeting Diagnosis, Therapy and Rehabilitation of Guangdong Higher Education Institutes, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
raw_author_name: Hui Zheng
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Yu Zhao
raw_affiliation_strings: Molecular Cancer Research Center, School of Medicine, Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen, China
raw_author_name: Peng Tang
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
raw_author_name: Jinkai Wang
raw_affiliation_strings: Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China
raw_author_name: Cristin Print
raw_affiliation_strings: Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
Maurice Wilkins Centre, University of Auckland, Auckland, New Zealand
raw_author_name: Ralf Jauch
raw_affiliation_strings: Centre for Translational Stem Cell Biology, Hong Kong, SAR, China
School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China
raw_author_name: Wensheng Zhang
raw_affiliation_strings: School of Life Sciences and Medicine, Shandong University of Technology, Zibo, China. zhangwensheng@suda.edu.cn
School of Life Sciences and Medicine, Shandong University of Technology, Zibo, China
raw_author_name: Guangming Wu
raw_affiliation_strings: Department of Basic Research, Guangzhou National Laboratory, Guangzhou, China. wu_guangming@gzlab.ac.cn
The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China. wu_guangming@gzlab.ac.cn
The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
raw_author_name: Xichen Bao
raw_affiliation_strings: Center for Cell Lineage Atlas, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. bao_xichen@gibh.ac.cn
China-New Zealand Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. bao_xichen@gibh.ac.cn
Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. bao_xichen@gibh.ac.cn
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. bao_xichen@gibh.ac.cn
University of Chinese Academy of Sciences, Beijing, China. bao_xichen@gibh.ac.cn
State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
University of Chinese Academy of Sciences, Beijing, China
Key Laboratory of Biological Targeting Diagnosis, Therapy and Rehabilitation of Guangdong Higher Education Institutes, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China
Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China