The G9a-TRIM21 axis exacerbates diabetic renal ischemia-reperfusion injury by inducing methylation-dependent ubiquitination and degradation of FoxO3a to promote oxidative stress and pyroptosis
Year: 2025
Type: article
Language: en
Topic: Inflammasome and immune disorders
Authors and affiliations:
raw_author_name: Qingyuan Zheng
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Xuke Qin
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Shiyu Huang
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Zhiwei Yan
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Jin Liu
raw_affiliation_strings: Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Yufeng Xiong
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Xiaojie Zhao
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Xinmiao Ni
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Haonan Mei
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Jun Jian
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Jingsong Wang
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Qianxue Lu
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Zhiyuan Chen
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Xiuheng Liu
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China
raw_author_name: Shanshan Wan
raw_affiliation_strings: Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China. Electronic address: ophwss@whu.edu.cn
raw_author_name: Hao Liu
raw_affiliation_strings: Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China. Electronic address: liuhao269@163.com
raw_author_name: Lei Wang
raw_affiliation_strings: Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China. Electronic address: drwanglei@whu.edu.cn