Design, synthesis, and biological evaluation of hybrids from both nitrones with eNOS-mimicking activity and selective iNOS inhibitors for the treatment of ischemic stroke
Year: 2025
Type: article
Language: en
Topic: Nitric Oxide and Endothelin Effects
Authors and affiliations:
raw_author_name: Weijie Jiao
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China; Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Hui Ye
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Duorui Ji
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Mengshuang Huang
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Ruichen Li
raw_affiliation_strings: Xinxiang Municipal Hospital of Traditional Chinese Medicine, Xinxiang, 453000, PR China
raw_author_name: Jian Jia
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Bowen Wang
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Shurui Wang
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Zhen Lei
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Nan Qin
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Hong Wu
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Xiaokun Li
raw_affiliation_strings: Xinxiang Municipal Hospital of Traditional Chinese Medicine, Xinxiang, 453000, PR China
raw_author_name: Guiyue Wu
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Yinglin Cui
raw_affiliation_strings: Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, 450002, PR China
raw_author_name: Yihua Zhang
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Jianbing Wu
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China
raw_author_name: Zhangjian Huang
raw_affiliation_strings: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, 211198, PR China; School of Pharmacy, Xinjiang Key Laboratory of Biopharmaceuticals and Medical Devices, Key Laboratory of Active Components of Xinjiang Natural Medicine and Drug Release Technology, Engineering Research Center of Xinjiang and Central Asian Medicine Resources, Xinjiang Medical University, Urumqi, 830054, PR China. Electronic address: zhangjianhuang@cpu.edu.cn