Exploring the genetic architecture of multiple long-term conditions using a genome-wide association study in the UK Biobank population
Year: 2025
Type: article
Language: en
Topic: Genetic Associations and Epidemiology
Authors and affiliations:
raw_author_name: Anand Thakarakkattil Narayanan Nair
raw_affiliation_strings: Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD1 9SY, UK
raw_author_name: Miles Witham
raw_affiliation_strings: AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland and Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Avan A. Sayer
raw_affiliation_strings: AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland and Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Heather J. Cordell
raw_affiliation_strings: Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Ewan R. Pearson
raw_affiliation_strings: Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD1 9SY, UK. e.z.pearson@dundee.ac.uk
Population Health and Genomics, School of Medicine, University of Dundee, Dundee, DD1 9SY, UK
raw_author_name: Victoria Bartle
raw_affiliation_strings: ADMISSION Research Collaborative, Newcastle Upon Tyne, UK
raw_author_name: Rachel Cooper
raw_affiliation_strings: AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland and Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Ray Holding
raw_affiliation_strings: ADMISSION Research Collaborative, Newcastle Upon Tyne, UK
raw_author_name: Tom Marshall
raw_affiliation_strings: Institute of Applied Health Research, University of Birmingham, Birmingham, UK
raw_author_name: Fiona E. Matthews
raw_affiliation_strings: Research and Enterprise Office, University of Hull, Hull, UK
raw_author_name: Paolo Missier
raw_affiliation_strings: Research and Enterprise Office, University of Hull, Hull, UK
raw_author_name: Chris Plummer
raw_affiliation_strings: Digital Services, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland and Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Sian M. Robinson
raw_affiliation_strings: AGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
NIHR Newcastle Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Cumbria Northumberland and Tyne and Wear NHS Foundation Trust and Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Elizabeth Sapey
raw_affiliation_strings: Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK
PIONEER Hub, University of Birmingham, Birmingham, UK
raw_author_name: Thomas Scharf
raw_affiliation_strings: Population Health Sciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, UK
raw_author_name: Mervyn Singer
raw_affiliation_strings: Bloomsbury Institute for Intensive Care Medicine, University College London, London, UK
University College London Hospitals NHS Foundation Trust, London, UK
raw_author_name: James M. S. Wason
raw_affiliation_strings: Biostatistics Research Group, Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK