Lopinavir/ritonavir induces hepatotoxicity in HepG2 cells through inhibition of the Nrf2 pathway, resulting in oxidative stress, endoplasmic reticulum stress, and cell cycle arrest
Year: 2025
Type: article
Language: en
Topic: Hepatitis C virus research
Authors and affiliations:
raw_author_name: Wenhong Zhou
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Dan Wang
raw_affiliation_strings: School of Pharmacy, Zunyi Medicinal University, Zunyi, China
raw_author_name: Jundou Tu
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Jun Li
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Jiayu Xu
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Wenjing Tan
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Diwei Mo
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Pengying Liang
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Yinglin Guo
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China
raw_author_name: Ming Hu
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China. Electronic address: 3110478@qq.com
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China. Electronic address: 3110478@qq.com
raw_author_name: Linhu Ye
raw_affiliation_strings: Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan 528200, China; School of Pharmacy, Zunyi Medicinal University, Zunyi, China. Electronic address: yelinhu@126.com
Department of Pharmacy, The Sixth Affiliated Hospital, School of Medicine, South China University of Technology, Foshan, 528200, China; School of Pharmacy, Zunyi Medicinal University, Zunyi, China. Electronic address: yelinhu@126.com