Tamoxifen metabolites acting via BKCa orchestrate the dynamics of K+ and Ca2+ in breast cancer cells
Year: 2025
Type: article
Language: en
Topic: Ion channel regulation and function
Authors and affiliations:
raw_author_name: Selina Maier
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany
raw_author_name: Werner Schroth
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany
raw_author_name: Finn Mier
raw_affiliation_strings: Laboratory for Molecular Design and Pharmaceutical Biophysics, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Laboratory for Molecular Design and Pharmaceutical Biophysics, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Lucas Matt
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Helmut Bischof
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Aiden Tamaddon
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Darko Stojkov
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Lena Birkenfeld
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Melanie Cruz Santos
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Dominic Gross
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Johanna Dahlen
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany
raw_author_name: Florian A. Büttner
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany
raw_author_name: Irina Bonzheim
raw_affiliation_strings: Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany
Institute of Pathology and Neuropathology, University Hospital Tübingen, Germany
raw_author_name: Falko Fend
raw_affiliation_strings: Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany
Institute of Pathology and Neuropathology, University Hospital Tübingen, Germany
raw_author_name: Hiltrud Brauch
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; Cluster of Excellence iFIT (EXC 2180) "Image-guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center, Partner Site Tübingen, Tübingen, Germany
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany; Cluster of Excellence iFIT (EXC 2180) "Image-guided and Functionally Instructed Tumor Therapies", University of Tübingen, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center, Partner Site Tübingen, Germany
raw_author_name: Frank M. Boeckler
raw_affiliation_strings: Laboratory for Molecular Design and Pharmaceutical Biophysics, Institute of Pharmacy, University of Tübingen, Tübingen, Germany; Interfaculty Institute for Biomedical Informatics (IBMI), University of Tübingen, Tübingen, Germany
Laboratory for Molecular Design and Pharmaceutical Biophysics, Institute of Pharmacy, University of Tübingen, Germany; Interfaculty Institute for Biomedical Informatics (IBMI), University Tübingen, Germany
raw_author_name: Matthias Schwab
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; Cluster of Excellence iFIT (EXC 2180) "Image-guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center, Partner Site Tübingen, Tübingen, Germany; Departments of Clinical Pharmacology, and Biochemistry and Pharmacy, University of Tübingen, Tübingen, Germany
Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany; Cluster of Excellence iFIT (EXC 2180) "Image-guided and Functionally Instructed Tumor Therapies", University of Tübingen, Germany; Departments of Clinical Pharmacology, and Biochemistry and Pharmacy, University Tübingen, Germany; German Cancer Consortium (DKTK) and German Cancer Research Center, Partner Site Tübingen, Germany
raw_author_name: Robert Lukowski
raw_affiliation_strings: Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Tübingen, Germany. Electronic address: robert.lukowski@uni-tuebingen.de
Department of Pharmacology, Toxicology and Clinical Pharmacy, Institute of Pharmacy, University of Tübingen, Germany. Electronic address: robert.lukowski@uni-tuebingen.de