Dual-target anti-vascular endothelial growth factor/tumor necrosis factor-α nanobody precisely intervenes in hypoxia-induced retinal neovascularization formation and inflammation activation
Year: 2025
Type: article
Language: en
Topic: Retinal Diseases and Treatments
Authors and affiliations:
raw_author_name: Qian Yang
raw_affiliation_strings: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, Fujian, China
Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian, China
raw_author_name: Yize Bian
raw_affiliation_strings: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Department of Pharmacy, The First Hospital of Putian City, Putian, Fujian, 351100, China
Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Department of pharmacy, The First Hospital of Putian City, Putian, Fujian, 351100,China
raw_author_name: Jie Zhou
raw_affiliation_strings: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, Fujian, China
Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian, China
raw_author_name: Xiaohui Wang
raw_affiliation_strings: Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, Fujian, China
Department of Ophthalmology, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, China
raw_author_name: Pengfen Gao
raw_affiliation_strings: Fuzhou Aier Eye Hospital, Fuzhou, 350000, Fujian, China
Fuzhou Aier Eye Hospital, Fuzhou 350000, Fujian, China
raw_author_name: Juhua Yang
raw_affiliation_strings: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China
raw_author_name: He Wang
raw_affiliation_strings: School of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China. Electronic address: 2013057@fjtcm.edu.cn
raw_author_name: Xiaole Chen
raw_affiliation_strings: Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, Fujian, China. Electronic address: leochen5139@fjmu.edu.cn
Department of Bioengineering and Biopharmaceutics, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China; Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian, China. Electronic address: leochen5139@fjmu.edu.cn
raw_author_name: Nanwen Zhang
raw_affiliation_strings: Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou, 350122, Fujian, China; Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China. Electronic address: znw@fjmu.edu.cn
Key Laboratory of Natural Medicine Pharmacology in Fujian Province, School of Pharmacy, Fujian Medical University, Fuzhou 350122, Fujian, China; Department of Pharmacology, School of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China. Electronic address: znw@fjmu.edu.cn