Setting the stage for cardiomyopathy gene editing trials: a systematic review of isogenic pair use in human induced pluripotent stem cell-derived cardiomyocyte research
Year: 2025
Type: article
Language: en
Topic: CRISPR and Genetic Engineering
Authors and affiliations:
raw_author_name: C Nina van der Wilt
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Rogier J A Veltrop
raw_affiliation_strings: Department of Biochemistry, CARIM, Maastricht University , Universiteitssingel 50, 6229 ER Maastricht ,
Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
LMNAcardiac.org, LMNA Patient Organization , Vredehofstraat 13761, HA Soest ,
Netherlands Heart Institute, Holland Heart House , Moreelsepark 1, 3511 EP Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Netherlands Heart Institute, Holland Heart House , Utrecht ,
LMNAcardiac.org, LMNA Patient Organization ,
Department of Biochemistry, CARIM, Maastricht University , Maastricht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Maaike H Janssens
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Iara Bakker
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Francesca Stillitano
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Netherlands Heart Institute, Holland Heart House , Moreelsepark 1, 3511 EP Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Netherlands Heart Institute, Holland Heart House , Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Joost P G Sluijter
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Linda W van Laake
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Jolanda van der Velden
raw_affiliation_strings: Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Center , De Boelelaan 1108, 1081 HZ Amsterdam ,
Department of Physiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Center , Amsterdam ,
raw_author_name: Eric Villard
raw_affiliation_strings: APHP, Pitié-Salpêtrière University Hospital , 47-83 Boulevard de l'Hôpital, 75013 Paris ,
ICAN Biocell iPS Core – Institute for Cardiometabolism and Nutrition , 47-83 Boulevard de l'Hôpital, 75013 Paris ,
Sorbonne Université, INSERM, UMRS 1166 , 47-83, Boulevard de l'Hôpital, 75013 Paris ,
Sorbonne Université, INSERM, UMRS 1166; APHP, Pitié-Salpêtrière University Hospital; and ICAN Biocell iPS core - Institute for Cardiometabolism and Nutrition , Paris ,
raw_author_name: Judith Montag
raw_affiliation_strings: Department of Human Medicine, Medical School Berlin , Rüdesheimer Str. 50, 14197 Berlin ,
Department of Human Medicine, Medical School Berlin , Berlin ,
raw_author_name: Chris Denning
raw_affiliation_strings: Biodiscovery Institute, University of Nottingham , Life Sciences Building University Park, NG7 2RD Nottingham ,
Biodiscovery Institute, University of Nottingham , Nottingham ,
raw_author_name: J Peter van Tintelen
raw_affiliation_strings: Department of Genetics, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Department of Genetics, University Medical Centre Utrecht, Utrecht University , Utrecht ,
raw_author_name: Anneline S J M te Riele
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Pim van der Harst
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Leon J Schurgers
raw_affiliation_strings: Department of Biochemistry, CARIM, Maastricht University , Universiteitssingel 50, 6229 ER Maastricht ,
Department of Biochemistry, CARIM, Maastricht University , Maastricht ,
raw_author_name: Frank G van Steenbeek
raw_affiliation_strings: Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University , Yalelaan 104-106, 3584 CM Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht University , Utrecht ,
raw_author_name: Magdalena Harakalova
raw_affiliation_strings: Department of Biochemistry, CARIM, Maastricht University , Universiteitssingel 50, 6229 ER Maastricht ,
Department of Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University , Heidelberglaan 100, 3584 CX Utrecht ,
Netherlands Heart Institute, Holland Heart House , Moreelsepark 1, 3511 EP Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Heidelberglaan 8, 3584 CS Utrecht ,
Regenerative Medicine Center Utrecht and Circulatory Health Research Center, University Medical Center Utrecht, Utrecht University , Utrecht ,
Netherlands Heart Institute, Holland Heart House , Utrecht ,
Department of Biochemistry, CARIM, Maastricht University , Maastricht ,