Astrocytic LCN2 drives neuronal dysfunction in epilepsy by suppressing tunnel nanotube-mediated mitochondrial transfer via NLRP3 inflammasome activation
Year: 2025
Type: article
Language: en
Topic: Inflammasome and immune disorders
Authors and affiliations:
raw_author_name: Zixian Zhou
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, 325000, Wenzhou, China
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China; Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, 325000 Wenzhou, China
raw_author_name: Pengcheng Zhang
raw_affiliation_strings: Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Yanlin Jiang
raw_affiliation_strings: Department of Neurology, The First Affiliated Hospital of Guilin Medical University, Guilin Medical University, 541004, Guilin, China
Department of Neurology, the First Affiliated Hospital of Guilin Medical University, Guilin Medical University, 541004 Guilin, China
raw_author_name: Yingchun Xu
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Fangzhou Liu
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Xinyu Chen
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Deng Chen
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Wenfu Tang
raw_affiliation_strings: Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, 610041, Chengdu, China
Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, 610041 Chengdu, China
raw_author_name: Rujia Liao
raw_affiliation_strings: Department of Neurology, The First Affiliated Hospital of Guilin Medical University, Guilin Medical University, 541004, Guilin, China. Electronic address: liaorujia@hotmail.com
Department of Neurology, the First Affiliated Hospital of Guilin Medical University, Guilin Medical University, 541004 Guilin, China. Electronic address: liaorujia@hotmail.com
raw_author_name: Ling Liu
raw_affiliation_strings: Department of Neurology, West China Hospital, Sichuan University, 610041, Chengdu, China. Electronic address: neurologyliuling@163.com
Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, China. Electronic address: neurologyliuling@163.com