Vulnerability of <i>SRSF2</i> -mutated chronic myelomonocytic leukemia to perturbation of the cGAS-STING pathway
Year: 2025
Type: article
Language: en
Topic: interferon and immune responses
Authors and affiliations:
raw_author_name: Yanan Chen
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Koon Chuen Chan
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, HKSAR, China
raw_author_name: Chun Fung Sin
raw_affiliation_strings: 2Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Lichuan Zheng
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Dandan Wang
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Lingge Tu
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong
raw_author_name: Fangfang He
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Wan Hei Jeffrey Hui
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Hoi Ki Leung
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Leslie Kar Fai Chan
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Sze Pui Tsui
raw_affiliation_strings: 2Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
Queen Mary Hospital, Hong Kong, Hong Kong
raw_author_name: Hoi yi Chan
raw_affiliation_strings: 2Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Alvin Chun Hang Ma
raw_affiliation_strings: 3Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR
4ZeBlast Technology Limited, Hong Kong Science Park, Hong Kong SAR
The Hong Kong Polytechnic University, Hong Kong, Hong Kong
raw_author_name: Anskar Y.H. Leung
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
4ZeBlast Technology Limited, Hong Kong Science Park, Hong Kong SAR
5Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR
University of Hong Kong, Hong Kong, Hong Kong
raw_author_name: Xuan Sun
raw_affiliation_strings: 1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR
4ZeBlast Technology Limited, Hong Kong Science Park, Hong Kong SAR
The University of Hong Kong, Hong Kong, Hong Kong