Rapid transcellular hepatic copper depletion by ARBM-101 rescues severe liver damage in Wilson disease rodents
Year: 2025
Type: article
Language: en
Topic: Trace Elements in Health
Authors and affiliations:
raw_author_name: Jonas Engler
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany
raw_author_name: Eun-Jung Kim
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Dasol Kim
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Noreene M. Shibata
raw_affiliation_strings: Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of California Davis, Davis, CA, USA
raw_author_name: Emilie Munk Lynderup
raw_affiliation_strings: Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark
raw_author_name: Mikkel H. Vendelbo
raw_affiliation_strings: Department of Nuclear Medicine and PET Center, Aarhus University Hospital, Aarhus, Denmark; Department of Biomedicine, Aarhus University, Aarhus, Denmark
raw_author_name: Banu Akdogan
raw_affiliation_strings: Institute of Molecular Toxicology and Pharmacology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany
raw_author_name: Judith Sailer
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany
raw_author_name: Adriana Fontes
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany; Institute of Molecular Toxicology and Pharmacology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany
raw_author_name: Carola Eberhagen
raw_affiliation_strings: Institute of Molecular Toxicology and Pharmacology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany
raw_author_name: Tamara Rieder
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany
raw_author_name: Quirin Reinold
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany
raw_author_name: Hongjae Lee
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Dongsik Park
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Chunwon Jung
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Weonbin Im
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Susanne I. Wudy
raw_affiliation_strings: Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), TUM School of Life Sciences, Technical University of Munich, Freising, Germany
raw_author_name: Karin Kleigrewe
raw_affiliation_strings: Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), TUM School of Life Sciences, Technical University of Munich, Freising, Germany
raw_author_name: Stefan Engelhardt
raw_affiliation_strings: Institute of Pharmacology and Toxicology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany
raw_author_name: Alan A. DiSpirito
raw_affiliation_strings: Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, IA, USA
raw_author_name: Thomas Damgaard Sandahl
raw_affiliation_strings: Department of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark
raw_author_name: Valentina Medici
raw_affiliation_strings: Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of California Davis, Davis, CA, USA
raw_author_name: So-Young Eun
raw_affiliation_strings: R&D Center, ArborMed Co. Ltd, Pangyo, Seongnam, Gyeonggi-do, Republic of Korea
raw_author_name: Hans Zischka
raw_affiliation_strings: Institute of Toxicology and Environmental Hygiene, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany; Institute of Molecular Toxicology and Pharmacology, Helmholtz Munich, German Research Center for Environmental Health, Neuherberg, Germany. Electronic address: hans.zischka@helmholtz-munich.de