Stratification of brain-derived extracellular vesicles of Alzheimer’s disease patients indicates a unique proteomic content and a higher seeding capacity of small extracellular vesicles
Year: 2025
Type: article
Language: en
Topic: Extracellular vesicles in disease
Authors and affiliations:
raw_author_name: Marie Oosterlynck
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Elodie Leroux
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Balasubramaniam Namasivayam
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Thomas Bouillet
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Raphaelle Caillierez
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Anne Loyens
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Daniele Mazur
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Romain Perbet
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Christophe Lefebvre
raw_affiliation_strings: Inserm, U1192-Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), University of Lille, Lille, France
raw_author_name: Soulaimane Aboulouard
raw_affiliation_strings: Inserm, U1192-Laboratoire Protéomique, Réponse Inflammatoire Et Spectrométrie de Masse (PRISM), University of Lille, Lille, France
raw_author_name: Claude-Alain Maurage
raw_affiliation_strings: CHU-Lille, CRB/CIC1403, Centre de Ressources Biologiques du Centre d'Investigation Clinique, University of Lille, Lille, France
raw_author_name: Bertrand Accart
raw_affiliation_strings: CHU-Lille, CRB/CIC1403, Centre de Ressources Biologiques du Centre d'Investigation Clinique, University of Lille, Lille, France
raw_author_name: Luc Buée
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France. luc.buee@inserm.fr
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France
raw_author_name: Morvane Colin
raw_affiliation_strings: Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine - pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France. morvane.colin@inserm.fr
Inserm UMR-S 1172, 'Alzheimer & Tauopathies', CHU-Lille, Lille Neuroscience & Cognition, Faculty of Medecine – pole recherche, University of Lille, Bâtiment Biserte, Rue Polonovski, 59000, Lille, France