Cardiovascular-Kidney Effects of Dapagliflozin in Patients at Cardiovascular Risk With or Without Type 2 Diabetes: Results of a Randomized, Double-Blind, Placebo-Controlled Trial
Year: 2025
Type: article
Language: en
Topic: Diabetes Treatment and Management
Authors and affiliations:
raw_author_name: Vikas S. Sridhar
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University of British Columbia, Vancouver, Canada (V.S.S.)
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
raw_author_name: Luxcia Kugathasan
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
raw_author_name: Yuliya Lytvyn
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
raw_author_name: Yangqing Deng
raw_affiliation_strings: Biostatistics Department (Y.D., L.E.L.), University Health Network, Toronto, Ontario, Canada
Biostatistics Department, University Health Network, Toronto, Ontario, Canada. (Y.D., L.E.L.)
raw_author_name: Hongyan Liu
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
raw_author_name: Leif Erik Lovblom
raw_affiliation_strings: Biostatistics Department (Y.D., L.E.L.), University Health Network, Toronto, Ontario, Canada
Institute of Health Policy, Management and Evaluation (L.E.L.), University of Toronto, Ontario, Canada
Biostatistics Department, University Health Network, Toronto, Ontario, Canada. (Y.D., L.E.L.)
Institute of Health Policy, Management and Evaluation, University of Toronto, Ontario, Canada. (L.E.L.)
raw_author_name: Josephine Tse
raw_affiliation_strings: Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
raw_author_name: Massimo Nardone
raw_affiliation_strings: Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
raw_author_name: John S. Floras
raw_affiliation_strings: Division of Cardiology, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada (J.S.F., T.O., T.T.)
raw_author_name: Tosin Osuntokun
raw_affiliation_strings: Division of Cardiology, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada (J.S.F., T.O., T.T.)
raw_author_name: Tomoyuki Tobushi
raw_affiliation_strings: Division of Cardiology, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada (J.S.F., T.O., T.T.)
raw_author_name: Ruthabella C.Y. Lam
raw_affiliation_strings: Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)
raw_author_name: Brian Lam
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
raw_author_name: Jasper Stevens
raw_affiliation_strings: Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands (J.S., D.J.T., H.J.L.H.)
raw_author_name: Dylan Burger
raw_affiliation_strings: Kidney Research Centre, Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada (D.B.)
raw_author_name: Daan J. Touw
raw_affiliation_strings: Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands (J.S., D.J.T., H.J.L.H.)
raw_author_name: Hiddo J.L. Heerspink
raw_affiliation_strings: Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands (J.S., D.J.T., H.J.L.H.)
raw_author_name: Julie A. Lovshin
raw_affiliation_strings: Department of Medicine, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.A.L.)
Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Endocrinology and Metabolism, Department of Medicine (J.A.L., B.A.P.), University of Toronto, Ontario, Canada
Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Ontario, Canada. (J.A.L., B.A.P.)
Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.A.L.)
raw_author_name: Bruce A. Perkins
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Endocrinology and Metabolism, Department of Medicine (J.A.L., B.A.P.), University of Toronto, Ontario, Canada
Division of Endocrinology and Metabolism, Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (B.A.P.)
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
raw_author_name: David Z.I. Cherney
raw_affiliation_strings: Department of Medicine, Temerty Faculty of Medicine (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.), University of Toronto, Ontario, Canada
Division of Nephrology, Department of Medicine (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.), University Health Network, Toronto, Ontario, Canada
Temerty Faculty of Medicine, University of Toronto, Ontario, Canada. (V.S.S., L.K., Y.L., H.L., B.L., J.A.L., B.A.P., D.Z.I.C.)
Division of Nephrology, Department of Medicine, University Health Network, Toronto, Ontario, Canada. (L.K., Y.L., H.L., J.T., M.N., R.C.Y.L., D.Z.I.C.)