Pancreatic Cancer Organoids Recapitulate Chemotherapy Response and Identify a Potent Cytotoxic T-Cell Population
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Renee R. Anderko
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
2UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Alexandra E. Bowman
raw_affiliation_strings: 3Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, United States
raw_author_name: Praneel Murthy
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Pranav Murthy
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Asmita Chopra
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, United States
raw_author_name: Nikhil V. Tirukkovalur
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Sebastiaan Ceuppens
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Alessandro Paniccia
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
4Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Kenneth K. Lee
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
4Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Robbie B. Mailliard
raw_affiliation_strings: 5Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Michael T. Lotze
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
2UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania
3Department of Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania
6Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania
University of Pittsburgh Cancer Institute, Pittsburgh, PA, United States
raw_author_name: Aatur D. Singhi
raw_affiliation_strings: 7Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States
raw_author_name: Amer H. Zureikat
raw_affiliation_strings: 1Division of Surgical Oncology, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania
2UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania
4Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
University of Pittsburgh, Pittsburgh, PA, United States