Metabolic engineering and late-stage functionalization expand the chemical space of the antimalarial premarineosin A
Year: 2025
Type: article
Language: en
Topic: Microbial Natural Products and Biosynthesis
Authors and affiliations:
raw_author_name: Christina M. McBride
raw_affiliation_strings: Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Morgan McCauley
raw_affiliation_strings: Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Natalia R. Harris
raw_affiliation_strings: Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Sahar Amin
raw_affiliation_strings: Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Brian J. Curtis
raw_affiliation_strings: Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Linnea Verhey-Henke
raw_affiliation_strings: Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Awet A. Teklemichael
raw_affiliation_strings: Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA
raw_author_name: Erin N. Oliphant
raw_affiliation_strings: National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD, USA
raw_author_name: Patricia Dranchak
raw_affiliation_strings: National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD, USA
raw_author_name: Katherine L. Lev
raw_affiliation_strings: Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Fengrui Qu
raw_affiliation_strings: Department of Chemistry, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Harrison M. Snodgrass
raw_affiliation_strings: Department of Chemistry, Indiana University, Bloomington, IN, USA
raw_author_name: Jared C. Lewis
raw_affiliation_strings: Department of Chemistry, Indiana University, Bloomington, IN, USA. jcl3@iu.edu
raw_author_name: James Inglese
raw_affiliation_strings: Metabolic Medicine Branch, National Human Genome Research Institute, NIH, Bethesda, MD, USA
National Center for Advancing Translational Sciences (NCATS), NIH, Rockville, MD, USA
raw_author_name: Xin-Zhuan Su
raw_affiliation_strings: Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Rockville, MD, USA
raw_author_name: Filipa Pereira
raw_affiliation_strings: Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA. fpere@umich.edu
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. fpere@umich.edu
raw_author_name: David H. Sherman
raw_affiliation_strings: Department of Chemistry, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu
Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu
Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA. davidhs@umich.edu