Linked-domain inhibitors designed to block UBE2D induce the unfolded protein response
Year: 2025
Type: article
Language: en
Topic: Ubiquitin and proteasome pathways
Authors and affiliations:
raw_author_name: Zara Bukhari
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Li Gu
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Anneroos E. Nederstigt
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Logan J. Cope
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Derek L. Bolhuis
raw_affiliation_strings: Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
raw_author_name: Kim Harvey
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Tristan Allen
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Spencer Hill
raw_affiliation_strings: Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Las Vegas, NV, USA
raw_author_name: Yujie Yang
raw_affiliation_strings: Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA
raw_author_name: Guy Lawson
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Cai Lu
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Tommy Tran
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Leah Pineda
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Leanne Low
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Andrew Chiang
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Jason Song
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Michelle V. Fong
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: Vanessa M. Rangel
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA
raw_author_name: William K. Chan
raw_affiliation_strings: Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA
raw_author_name: Gary Kleiger
raw_affiliation_strings: Department of Chemistry and Biochemistry, University of Nevada, Las Vegas, Las Vegas, NV, USA
raw_author_name: Dennis Goldfarb
raw_affiliation_strings: Department of Cell Biology and Physiology, Institute for Informatics, Washington University, St. Louis, MO, USA
raw_author_name: Craig A. Vierra
raw_affiliation_strings: Biological Sciences Department, University of the Pacific, Stockton, CA 95211, USA
raw_author_name: Nicholas G. Brown
raw_affiliation_strings: Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA
raw_author_name: Joseph S. Harrison
raw_affiliation_strings: The University of the Pacific, Department of Chemistry, Stockton, CA 95210, USA. Electronic address: jharrison@pacific.edu