Additive Clinical Utility of Microsatellite Instability and Tumor Mutational Burden to Predict Immune Checkpoint Inhibitor Effectiveness in Metastatic Castration-Resistant Prostate Cancer
Year: 2025
Type: article
Language: en
Topic: Prostate Cancer Treatment and Research
Authors and affiliations:
raw_author_name: Nicolas Sayegh
raw_affiliation_strings: 1Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
2Division of Hematology and Oncology, Department of Internal Medicine, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas
Huntsman Cancer Institute, University of Utah (NCI-CCC), Salt Lake City, Utah, United States
raw_author_name: Ryon P. Graf
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
Foundation Medicine, San Diego, CA, United States
raw_author_name: Umang Swami
raw_affiliation_strings: 1Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Huntsman Cancer Institute, Salt Lake City, United States
raw_author_name: Zeynep Irem Ozay
raw_affiliation_strings: 1Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Huntsman Cancer Institute, Salt Lake City, United States
raw_author_name: Chadi Hage Chehade
raw_affiliation_strings: 1Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Huntsman Cancer Institute, Salt Lake City, United States
raw_author_name: Julia A. Elvin
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
AstraZeneca (United States), Waltham, Massachusetts, United States
raw_author_name: Douglas Lin
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
Foundation Medicine, Boston, MA, United States
raw_author_name: Julia C.F. Quintanilha
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
Foundation Medicine, Cambridge, MA, United States
raw_author_name: Gerald Li
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
Foundation Medicine, Cambridge, MA, United States
raw_author_name: Alan H. Bryce
raw_affiliation_strings: 4Department of Medical Oncology and Therapeutics Research, City of Hope, Phoenix, Arizona
City Of Hope National Medical Center, Phoenix, AZ, United States
raw_author_name: Rana R. McKay
raw_affiliation_strings: 5Department of Medicine, University of California San Diego, La Jolla, California
University of California, San Diego, La Jolla, CA, United States
raw_author_name: Jeffrey S. Ross
raw_affiliation_strings: 3Foundation Medicine, Cambridge, Massachusetts
SUNY Upstate Medical University, Syracuse, NY, United States
raw_author_name: Tian Zhang
raw_affiliation_strings: 2Division of Hematology and Oncology, Department of Internal Medicine, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas
The University of Texas Southwestern Medical Center, Dallas, TX, United States
raw_author_name: Neeraj Agarwal
raw_affiliation_strings: 1Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah
Huntsman Cancer Institute, Salt lake City, UT, United States