Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Antitumor Immunity
Year: 2025
Type: article
Language: en
Topic: Hedgehog Signaling Pathway Studies
Authors and affiliations:
raw_author_name: Deepika Singh
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Benjamin C. Onyeagucha
raw_affiliation_strings: 3Department of Sciences and Mathematics, Mississippi University for Women, Columbus, Mississippi
Mississippi University for Women, San Antonio, TX, United States
raw_author_name: Daisy Medina
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Panneerdoss Subbarayalu
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
Greehey Children's Cancer Research Institute, San Antonio, Texas, United States
raw_author_name: Rahul Mojidra
raw_affiliation_strings: 4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Dongwen Lv
raw_affiliation_strings: 4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
5Barshop Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, United States
raw_author_name: Mukund Bhandari
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Southwestern Medical Center, Dallas, Texas, United States
raw_author_name: Santosh Timilsina
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
raw_author_name: Prabhakar Pitta Venkata
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
Mays Cancer Center at UT Health San Antonio, United States
raw_author_name: Jian Yu Huang
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Saif Nirzhor
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
raw_author_name: Shahad Abdulsahib
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Jack Yancy Prochnau
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Chris T.P. Do
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Subapriya Rajamanickam
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
raw_author_name: Yidong Chen
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
6Department of Epidemiology and Biostatistics, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, United States
raw_author_name: Alexander B. Taylor
raw_affiliation_strings: 4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Suryavathi Viswanadhapalli
raw_affiliation_strings: 7Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Maria E. Falzone
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Jean Jiang
raw_affiliation_strings: 4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at Houston, San Antonio, TX, United States
raw_author_name: Patrick Sung
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Daohong Zhou
raw_affiliation_strings: 4Department of Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
5Barshop Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, United States
raw_author_name: Ratna K. Vadlamudi
raw_affiliation_strings: 7Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States
raw_author_name: Robert Hromas
raw_affiliation_strings: 8Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas at San Antonio, San Antonio, United States
raw_author_name: Manjeet K. Rao
raw_affiliation_strings: 1Greehey Children’s Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, Texas
2Department of Cell Systems and Anatomy, University of Texas Health Science Center at San Antonio, San Antonio, Texas
The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States