Genetic alterations of SENP6 in multiple myeloma disrupt genome and proteome stability, sensitizing to proteasome inhibition
Year: 2025
Type: article
Language: en
Topic: Ubiquitin and proteasome pathways
Authors and affiliations:
raw_author_name: Frederik Herzberg
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
raw_author_name: Michael Korenkov
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
raw_author_name: Konstandina Isaakidis
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
raw_author_name: Chuanbing Zang
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
raw_author_name: Matthias Wirth
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany; German Consortium for Translational Cancer Research (DKTK), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg
Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, 37075 Göttingen, Germany
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
German Consortium for Translational Cancer Research (DKTK), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg
raw_author_name: Stefan Müller
raw_affiliation_strings: German Consortium for Translational Cancer Research (DKTK), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Institute of Biochemistry II, Goethe University Frankfurt, Medical School, 60590 Frankfurt
Institute of Biochemistry II, Goethe University Frankfurt, Medical School, 60590 Frankfurt
German Consortium for Translational Cancer Research (DKTK), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
raw_author_name: Ulrich Keller
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; German Consortium for Translational Cancer Research (DKTK), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; National Center for Tumor Diseases (NCT), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Cluster of Excellence ImmunoPreCept, Charité - Universitätsmedizin Berlin, Berlin
National Center for Tumor Diseases (NCT), partner site Berlin, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
raw_author_name: Uta M. Demel
raw_affiliation_strings: Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany; Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany; Clinician Scientist Program, Berlin Institute of Health (BIH), Berlin. uta.demel@charite.de
Department of Hematology, Oncology and Cancer Immunology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany
Clinician Scientist Program, Berlin Institute of Health (BIH), Berlin
Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany