Structure guided analysis of KRAS G12 mutants in HLA-A*11:01 reveals a length encoded immunogenic advantage in G12D
Year: 2025
Type: article
Language: en
Topic: T-cell and B-cell Immunology
Authors and affiliations:
raw_author_name: Jiali Zhu
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Zhifeng Chen
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Xi Xu
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Yuxuan Wang
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Pei Liu
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Maorong Wen
raw_affiliation_strings: Hangzhou Weizhi Biotechnology Co., Ltd, Hangzhou, China
raw_author_name: Quanmeng Wang
raw_affiliation_strings: Tongji University Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Yuchen He
raw_affiliation_strings: Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Hongwei Jin
raw_affiliation_strings: State key laboratory of natural and biomimetic drugs, Peking University Health Science Center, Beijing, China
raw_author_name: Hongjuan Xue
raw_affiliation_strings: National Facility for Protein Science in Shanghai, ZhangJiang lab, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, China
raw_author_name: Shuqing Wang
raw_affiliation_strings: Tianjin Key Laboratory of Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin, China
raw_author_name: Ke Xu
raw_affiliation_strings: Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China. kx2129@tongji.edu.cn
Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Clinical Research Center for Anesthesiology and Perioperative Medicine, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai, China
raw_author_name: Linlin Zhao
raw_affiliation_strings: Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China. lzhao@tongji.edu.cn
Department of Anesthesiology, Putuo People's Hospital, School of Medicine, Tongji University, Shanghai, China