Clinically informed intermediate reasoning enables generalizable prostate cancer prognostication through machine learning in limited settings
Year: 2025
Type: article
Language: en
Topic: AI in cancer detection
Authors and affiliations:
raw_author_name: Jun Akatsuka
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Kotaro Tsutsumi
raw_affiliation_strings: Department of Neurology, University of California, Irvine, Orange, CA, USA
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Mami Takadate
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
Mathematical Intelligence for Medicine, Graduate School of Medicine, Tohoku University, Miyagi, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Yasushi Numata
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Hiromu Morikawa
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Atsushi Marugame
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Hayato Takeda
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Yuki Endo
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
raw_author_name: Yuka Toyama
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
raw_author_name: Takayuki Takahashi
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Kaori Ono
raw_affiliation_strings: Mathematical Intelligence for Medicine, Graduate School of Medicine, Tohoku University, Miyagi, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Junya Iwazaki
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Ryuji Ohashi
raw_affiliation_strings: Department of Integrated Diagnostic Pathology, Nippon Medical School, Tokyo, Japan
raw_author_name: Akira Shimizu
raw_affiliation_strings: Department of Analytic Human Pathology, Nippon Medical School, Tokyo, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Tomoharu Kiyuna
raw_affiliation_strings: Medical Solutions Department, NEC Corporation, Tokyo, Japan
raw_author_name: Maki Ogura
raw_affiliation_strings: Medical Solutions Department, NEC Corporation, Tokyo, Japan
raw_author_name: Masao Ueki
raw_affiliation_strings: Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
School of Information and Data Sciences, Nagasaki University, Nagasaki, Japan
raw_author_name: Takuma Kato
raw_affiliation_strings: Department of Urology, Faculty of Medicine, Kagawa University, Kagawa, Japan
raw_author_name: Toshiyuki China
raw_affiliation_strings: Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan
raw_author_name: Mikio Sugimoto
raw_affiliation_strings: Department of Urology, Faculty of Medicine, Kagawa University, Kagawa, Japan
raw_author_name: Hisamitsu Ide
raw_affiliation_strings: Department of Innovative Longevity, Juntendo University Graduate School of Medicine, Tokyo, Japan
Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan
raw_author_name: Naoto Sassa
raw_affiliation_strings: Department of Urology, Aichi Medical University Hospital, Aichi, Japan
raw_author_name: Naonori Ueda
raw_affiliation_strings: Goal-Oriented Technology Research Group, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Shigeo Horie
raw_affiliation_strings: Department of Innovative Longevity, Juntendo University Graduate School of Medicine, Tokyo, Japan
Department of Urology, Juntendo University Graduate School of Medicine, Tokyo, Japan
raw_author_name: Toyonori Tsuzuki
raw_affiliation_strings: Department of Surgical Pathology, Aichi Medical University Hospital, Aichi, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Go Kimura
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Yukihiro Kondo
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan
raw_author_name: Yoichiro Yamamoto
raw_affiliation_strings: Department of Urology, Nippon Medical School, Tokyo, Japan. yoichiro.yamamoto@riken.jp
Mathematical Intelligence for Medicine, Graduate School of Medicine, Tohoku University, Miyagi, Japan. yoichiro.yamamoto@riken.jp
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan. yoichiro.yamamoto@riken.jp
Department of Urology, Nippon Medical School, Tokyo, Japan
Mathematical Intelligence for Medicine, Graduate School of Medicine, Tohoku University, Miyagi, Japan
Pathology Informatics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan