FAME-CRISPR improves CRISPR-Cas9 genome editing via HDAC inhibition and engineered virus-like particle delivery
Year: 2025
Type: article
Language: en
Topic: CRISPR and Genetic Engineering
Authors and affiliations:
raw_author_name: Mahbod Djamshidi
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Alexander Hill
raw_affiliation_strings: Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada
raw_author_name: Katayoun Heshmatzad
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Jethro Langley
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Hokan Krowicki
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Motamed Ali
raw_affiliation_strings: Departments of Ecosystem and Public Health, University of Calgary, Calgary, AB, Canada; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Yang Yang
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Ryota Tanida
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Mohamed Faizal Abdul-Careem
raw_affiliation_strings: Departments of Ecosystem and Public Health, University of Calgary, Calgary, AB, Canada; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Pierre Billon
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
raw_author_name: Karl Riabowol
raw_affiliation_strings: Robson DNA Sciences Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada; Arthur JE Childs Comprehensive Cancer Institute, University of Calgary, Calgary, AB, Canada; Departments of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Department of Oncology, University of Calgary, Calgary, AB, Canada; Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. Electronic address: karl@ucalgary.ca