Machine learning enables de novo multiepitope design of <i>Plasmodium falciparum</i> circumsporozoite protein to target trimeric L9 antibody
Year: 2025
Type: article
Language: en
Topic: Malaria Research and Control
Authors and affiliations:
raw_author_name: J. Andrew D. Nelson
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Department of Biochemistry and Biophysics, The University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
Department of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104
raw_author_name: Samuel E. Garfinkle
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Department of Biochemistry and Biophysics, The University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Zi Jie Lin
raw_affiliation_strings: Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Joyce Park
raw_affiliation_strings: Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Amber J. Kim
raw_affiliation_strings: Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Kelly Bayruns
raw_affiliation_strings: Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Madison E. McCanna
raw_affiliation_strings: Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Kylie M. Konrath
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Colby J. Agostino
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Department of Biochemistry and Biophysics, The University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Department of Biochemistry and Biophysics, The University of Pennsylvania, Philadelphia, PA 19104
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Daniel W. Kulp
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Department of Biochemistry and Biophysics, The University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
raw_author_name: Audrey R. Odom John
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Division of Infectious Diseases, Children’s Hospital of Philadelphia
Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104
Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA 19104
raw_author_name: Jesper Pallesen
raw_affiliation_strings: Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania
Department of Biochemistry and Biophysics, The University of Pennsylvania
Vaccine and Immunotherapy Center, The Wistar Institute
Vaccine and Immunotherapy Center, The Wistar Institute, Philadelphia, PA 19104
Biomedical Graduate Studies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104