Discovery of a small molecule TLR3 agonist adjuvant
Year: 2025
Type: article
Language: en
Topic: Immune Response and Inflammation
Authors and affiliations:
raw_author_name: Branden Lee
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Danica Dong
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Etsuro Nanishi
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: John Mark Awad
raw_affiliation_strings: Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, Boston, MA, USA
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Kimia Z. Abedi
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Yoshine Saito
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Francesco Borriello
raw_affiliation_strings: Generate Biomedicines, Somerville, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Soumik Barman
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Byron Brook
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Aisling Kelly
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Manisha Menon
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Constance Marques-Mourlet
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Maansi V. Gupta
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Ida Lister
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Chiwoo Oh
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Kevin Lyskawa
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Morgan Goetz
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Kristina Walker
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Wing Ki Cheng
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Spencer E. Brightman
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Pankaj Sharma
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Timothy R. O’Meara
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Katherine Chew
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Daniel Vieira
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Kevin Ryff
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Cali Sweitzer
raw_affiliation_strings: Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Sanya Thomas
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Simon D. van Haren
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Matthew Pettengill
raw_affiliation_strings: Department of Pathology and Genomic Medicine, Thomas Jefferson University, Philadelphia, PA, USA
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: Hyuk-Soo Seo
raw_affiliation_strings: Dana-Farber Cancer Institute, Boston, MA, USA
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
raw_author_name: Sirano Dhe-Paganon
raw_affiliation_strings: Dana-Farber Cancer Institute, Boston, MA, USA
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
raw_author_name: Wei Zhang
raw_affiliation_strings: Center for Green Chemistry and Department of Chemistry, University of Massachusetts Boston, Boston, MA, USA
raw_author_name: Ofer Levy
raw_affiliation_strings: Broad Institute of MIT & Harvard, Cambridge, MA, USA
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA
raw_author_name: David J. Dowling
raw_affiliation_strings: Department of Pediatrics, Harvard Medical School, Boston, MA, USA. David.Dowling@childrens.harvard.edu
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA. David.Dowling@childrens.harvard.edu
Department of Pediatrics, Harvard Medical School, Boston, MA, USA
Precision Vaccines Program, Boston Children's Hospital, Boston, MA, USA