Drug targeting of the monocarboxylate transporter MCT4 is a novel treatment strategy for metastatic ccRCC
Year: 2025
Type: article
Language: en
Topic: Cancer, Hypoxia, and Metabolism
Authors and affiliations:
raw_author_name: Lena-Sophie Menig-Benzig
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: Lena-Sophie.Menig-Benzig@med.uni-tuebingen.de
raw_author_name: Viktoria Stühler
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: Viktoria.Stuehler@med.uni-tuebingen.de
raw_author_name: Pascale Mazzola
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: pascale.mazzola@med.uni-tuebingen.de
raw_author_name: Hannah Heinrich
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: hannah.heinrich@ikp-stuttgart.de
raw_author_name: Ute Hofmann
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: ute.hofmann@ikp-stuttgart.de
raw_author_name: Natalie Widmann
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: natalie.widmann@ikp-stuttgart.de
raw_author_name: Regina Bohnert
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: Regina.Bohnert@ikp-stuttgart.de
raw_author_name: Sylvia K. Neef
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: Sylvia.neef@ikp-stuttgart.de
raw_author_name: Carolin Sauter-Meyerhoff
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: Carolin.Sauter-Meyerhoff@humangenetik-tuebingen.de
raw_author_name: Christian Schmees
raw_affiliation_strings: NMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany. Electronic address: Christian.Schmees@nmi.de
raw_author_name: Anika Fuhr
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: anika.fuhr@outlook.de
raw_author_name: Verena Klumpp
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: verena-klumpp@gmx.de
raw_author_name: Steffen Rausch
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: steffen.rausch@med.uni-tuebingen.de
raw_author_name: Dennis Gürgen
raw_affiliation_strings: Experimental Pharmacology and Oncology Berlin-Buch GmbH (EPO), Berlin, Germany. Electronic address: dennis.guergen@epo-berlin.com
raw_author_name: Thomas E. Mürdter
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: thomas.muerdter@ikp-stuttgart.de
raw_author_name: Stefan Winter
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: stefan.winter@ikp-stuttgart.de
raw_author_name: Florian A. Büttner
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany. Electronic address: florian.buettner@ikp-stuttgart.de
raw_author_name: Stephan Kruck
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: Stephan.Kruck@siloah.de
raw_author_name: Anaïs Choffart
raw_affiliation_strings: Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University of Tübingen, Tübingen, Germany; German Cancer Consortium (DKTK), Partner Site Tübingen, German Cancer Research Center (DKFZ), Heidelberg, Germany; Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany. Electronic address: Anais.Choffart@med.uni-tuebingen.de
raw_author_name: André F. Martins
raw_affiliation_strings: Department of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, University of Tübingen, Tübingen, Germany; German Cancer Consortium (DKTK), Partner Site Tübingen, German Cancer Research Center (DKFZ), Heidelberg, Germany; Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany. Electronic address: Andre.Martins@med.uni-tuebingen.de
raw_author_name: Jörg Hennenlotter
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: joerg.hennenlotter@med.uni-tuebingen.de
raw_author_name: Maria Luisa Barcena
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: Maria.Luisa.Barcena@med.uni-tuebingen.de
raw_author_name: Olesya Vakhrusheva
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: olesya.vakhrusheva@med.uni-tuebingen.de
raw_author_name: Veronika Bahlinger
raw_affiliation_strings: Institute of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: veronika.bahlinger@med.uni-tuebingen.de
raw_author_name: Falko Fend
raw_affiliation_strings: Institute of Pathology and Neuropathology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: falko.fend@med.uni-tuebingen.de
raw_author_name: Igor Tsaur
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany. Electronic address: Igor.Tsaur@med.uni-tuebingen.de
raw_author_name: Jens Bedke
raw_affiliation_strings: Department of Urology, University Hospital Tuebingen, Tuebingen, Germany; Department of Urology & Transplantation Surgery, Eva Mayr-Stihl Cancer Center, Klinikum Stuttgart, Stuttgart, Germany. Electronic address: bedke@live.com
raw_author_name: Matthias Schwab
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany; German Cancer Consortium (DKTK), Partner Site Tübingen, German Cancer Research Center (DKFZ), Heidelberg, Germany; Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany; Departments of Clinical Pharmacology, Pharmacy and Biochemistry, University of Tuebingen, Tuebingen, Germany. Electronic address: matthias.schwab@ikp-stuttgart.de
raw_author_name: Elke Schaeffeler
raw_affiliation_strings: Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany; University of Tuebingen, Tuebingen, Germany; Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany. Electronic address: elke.schaeffeler@ikp-stuttgart.de