Dysregulation of RUNX1 isoforms drives mitochondrial defects during neural differentiation in down syndrome
Year: 2025
Type: article
Language: en
Topic: Down syndrome and intellectual disability research
Authors and affiliations:
raw_author_name: Yan-na Liu
raw_affiliation_strings: Shanghai Children's Hospital, Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China; NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China
raw_author_name: Qin Cai
raw_affiliation_strings: Shanghai Children's Hospital, Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China; NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China
raw_author_name: Ke-yi Li
raw_affiliation_strings: Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, China
raw_author_name: Wen-xiu Li
raw_affiliation_strings: Shanghai Children's Hospital, Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China; NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China
raw_author_name: Guang He
raw_affiliation_strings: NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030, China
raw_author_name: Fanyi Zeng
raw_affiliation_strings: Shanghai Children's Hospital, Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China; NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China; Department of Histoembryology, Genetics & Development, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China. Electronic address: fzeng@vip.163.com
raw_author_name: Jing-bin Yan
raw_affiliation_strings: Shanghai Children's Hospital, Shanghai Institute of Medical Genetics, Shanghai Jiao Tong University School of Medicine, 24/1400 West Beijing Road, Shanghai 200040, China; NHC Key Laboratory of Medical Embryogenesis and Developmental Molecular Biology, Shanghai Key Laboratory of Embryo and Reproduction Engineering, 24/1400 West Beijing Road, Shanghai 200040, China. Electronic address: yanjb@shchildren.com.cn