Genetic Correction of the Most Common Mutation Causing Primary Hyperoxaluria Restores Enzyme Localization and Oxalate Metabolism
Year: 2025
Type: article
Language: en
Topic: Kidney Stones and Urolithiasis Treatments
Authors and affiliations:
raw_author_name: Timo Keskinen
raw_affiliation_strings: Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
raw_author_name: Sami Jalil
raw_affiliation_strings: Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
raw_author_name: Irem Gümüşoğlu
raw_affiliation_strings: Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
raw_author_name: Juhana Juutila
raw_affiliation_strings: Faculty of Biological and Environmental Sciences, University of Helsinki  Helsinki Finland
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki  Helsinki Finland
Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland
raw_author_name: Nadim Kestilä
raw_affiliation_strings: Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
raw_author_name: Emilia Kuuluvainen
raw_affiliation_strings: Faculty of Biological and Environmental Sciences, University of Helsinki  Helsinki Finland
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki  Helsinki Finland
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
raw_author_name: Ville Hietakangas
raw_affiliation_strings: Faculty of Biological and Environmental Sciences, University of Helsinki  Helsinki Finland
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki  Helsinki Finland
Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland
raw_author_name: Diego Balboa
raw_affiliation_strings: Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
raw_author_name: Kirmo Wartiovaara
raw_affiliation_strings: Clinical Genetics, Helsinki University Hospital  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
Clinical Genetics, Helsinki University Hospital, Helsinki, Finland
raw_author_name: Mervi E. Hyvönen
raw_affiliation_strings: New Children's Hospital, Pediatric Research Center, Helsinki University Hospital  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki  Helsinki Finland
Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland
New Children's Hospital, Pediatric Research Center, Helsinki University Hospital, Helsinki, Finland