Biomarkers of LRRK2 and lysosomal dysfunction in Progressive Supranuclear Palsy
Year: 2025
Type: preprint
Topic: Parkinson's Disease Mechanisms and Treatments
Authors and affiliations:
raw_author_name: Louise-Kristine Nielsen
raw_affiliation_strings: Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK;
raw_author_name: Joshua LI Frost
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: David P Vaughan
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Raquel Real
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Riona Fumi
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Marte Theilmann Jensen
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Megan Hodgson
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Eleanor J. Stafford
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Lesley Wu
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Olaf Ansorge
raw_affiliation_strings: Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;
raw_author_name: Annelies Quaegebeur
raw_affiliation_strings: Department of Clinical Neurosciences, Cambridge University Hospitals NHS Trust and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK;
raw_author_name: Kieren SJ Allinson
raw_affiliation_strings: Department of Clinical Neurosciences, Cambridge University Hospitals NHS Trust and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK;
raw_author_name: Thomas T Warner
raw_affiliation_strings: Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Zane Jaunmuktane
raw_affiliation_strings: Queen Square Brain Bank for Neurological Disorders, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Anjum Misbahuddin
raw_affiliation_strings: Department of Neurology, Queens Hospital, Romford, UK;
raw_author_name: P Nigel Leigh
raw_affiliation_strings: Department of Neuroscience, Brighton and Sussex Medical School, University of Brighton and University of Sussex, Brighton, BN1 9PX, UK;
raw_author_name: Boyd CP Ghosh
raw_affiliation_strings: Wessex Neurological Centre, University Hospitals Southampton NHS Foundation Trust, UK;
raw_author_name: Kailash P Bhatia
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Alistair Church
raw_affiliation_strings: Department of Neurology, Royal Gwent Hospital, Newport, UK;
raw_author_name: Christopher Kobylecki
raw_affiliation_strings: Department of Neurology, Northern Care Alliance NHS Foundation Trust, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK;
raw_author_name: Michele TM Hu
raw_affiliation_strings: Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK;
raw_author_name: James B Rowe
raw_affiliation_strings: Department of Clinical Neurosciences, Cambridge University Hospitals NHS Trust and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK;
raw_author_name: Alan A Shomo
raw_affiliation_strings: Neurodegenerative Diseases Research Unit, Biogen, Cambridge, Massachusetts, USA
raw_author_name: Danielle L Graham
raw_affiliation_strings: Neurodegenerative Diseases Research Unit, Biogen, Cambridge, Massachusetts, USA
raw_author_name: Omar S Mabrouk
raw_affiliation_strings: Neurodegenerative Diseases Research Unit, Biogen, Cambridge, Massachusetts, USA
raw_author_name: Huw R Morris
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;
raw_author_name: Esther M Sammler
raw_affiliation_strings: Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK;
raw_author_name: Edwin Jabbari
raw_affiliation_strings: Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, London, UK;