Use of a cytochrome P450 humanised mouse model to refine schistosomiasis drug discovery
Year: 2025
Type: preprint
Topic: Parasites and Host Interactions
Authors and affiliations:
raw_author_name: Sarah D. Davey
raw_affiliation_strings: Department of Life Sciences, Aberystwyth University;
Department of Life Sciences, Aberystwyth University
raw_author_name: Josephine E. Forde-Thomas
raw_affiliation_strings: Department of Life Sciences, Aberystwyth University;
Department of Life Sciences, Aberystwyth University
raw_author_name: Benjamin J. Hulme
raw_affiliation_strings: Department of Life Sciences, Aberystwyth University;
Department of Life Sciences, Aberystwyth University
raw_author_name: Kristin Lees
raw_affiliation_strings: Department of Life Sciences, Aberytwyth University;
Department of Life Sciences, Aberytwyth University
raw_author_name: Alice H. Costain
raw_affiliation_strings: The University of Manchester Faculty of Biology Medicine and Health;
The University of Manchester Faculty of Biology Medicine and Health
raw_author_name: Mary Evans
raw_affiliation_strings: Department of Life Sciences, Aberystwyth University;
Department of Life Sciences, Aberystwyth University
raw_author_name: Gabriel Rinaldi
raw_affiliation_strings: University of Oxford;
University of Oxford
raw_author_name: Laura Frame
raw_affiliation_strings: Drug Discovery Unit, School of Life Sciences; University of Dundee;
Drug Discovery Unit, School of Life Sciences
University of Dundee
raw_author_name: Laste Stojanovski
raw_affiliation_strings: Drug Discovery Unit, School of Life Sciences; University of Dundee;
University of Dundee
Drug Discovery Unit, School of Life Sciences
raw_author_name: Frederick R. C. Simeons
raw_affiliation_strings: Drug Discovery Unit, School of Life Sciences; University of Dundee;
Drug Discovery Unit, School of Life Sciences
University of Dundee
raw_author_name: Amy Tavendale
raw_affiliation_strings: Drug Discovery Unit, School of Life Sciences; University of Dundee;
University of Dundee
Drug Discovery Unit, School of Life Sciences
raw_author_name: A. Kenneth MacLeod
raw_affiliation_strings: Drug Discovery Unit, School of Life Sciences; University of Dundee;
University of Dundee
Drug Discovery Unit, School of Life Sciences
raw_author_name: Remi Pichon
raw_affiliation_strings: Department of Biology, Oxford University;
Department of Biology, Oxford University
raw_author_name: Yi-Hsuan Lee
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Oktawia Polak
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Iain W. Chalmers
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Bismark Dankwa
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Brenda Kisia Odhiambo
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Victor Hugo Guimaraes
raw_affiliation_strings: Federal University of Sao Carlos;
Federal University of Sao Carlos
raw_author_name: Matthew Hegarty
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Martin T. Swain
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Wayne Aubrey
raw_affiliation_strings: Aberystwyth University;
Aberystwyth University
raw_author_name: Nicola Caldwell
raw_affiliation_strings: University of Dundee;
University of Dundee
raw_author_name: Andrew S. MacDonald
raw_affiliation_strings: The University of Edinburgh Institute of Immunology and Infection Research;
The University of Edinburgh Institute of Immunology and Infection Research
raw_author_name: Ian H. Gilbert
raw_affiliation_strings: University of Dundee;
University of Dundee
raw_author_name: Beatriz Baragaña
raw_affiliation_strings: University of Dundee;
University of Dundee
raw_author_name: Kevin D. Read
raw_affiliation_strings: University of Dundee;
University of Dundee
raw_author_name: Karl F. Hoffmann
raw_affiliation_strings: Department of Life Sciences