Formononetin inhibits colorectal cancer via the miR-490-3p/ABCC2 axis and synergizes with 5-fluorouracil: mechanistic insights and therapeutic implications
Year: 2025
Type: article
Language: en
Topic: Drug Transport and Resistance Mechanisms
Authors and affiliations:
raw_author_name: Hong Yu
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: 15310505297@163.com
raw_author_name: Muyan Kong
raw_affiliation_strings: The Seventh Affiliated Hospital of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518000, PR China. Electronic address: kmy_1995n@163.com
raw_author_name: Jinyi Chen
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: 18675193307@163.com
raw_author_name: Jiyao Liu
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: liu_jiyao@163.com
raw_author_name: Keyao Shan
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: sky1020189@163.com
raw_author_name: Guiyu Zhang
raw_affiliation_strings: The Seventh Affiliated Hospital of Guangzhou University of Chinese Medicine, Shenzhen, Guangdong 518000, PR China. Electronic address: zhangguiyu@gzucm.edu.cn
raw_author_name: Ruidi Jiang
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: ruidi2001@126.com
raw_author_name: Yinli Zheng
raw_affiliation_strings: State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Department of Pathology, Guangzhou 510060, PR China. Electronic address: zhengyinl@sysucc.org.cn
raw_author_name: Qiulu Chen
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: 19806453319@163.com
raw_author_name: Rong Zhang
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: zhangrong@gzucm.edu.cn
raw_author_name: Zhongqiu Liu
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: liuzq@gzucm.edu.cn
raw_author_name: Jinjun Wu
raw_affiliation_strings: State Key Laboratory of Traditional Chinese Medicine Syndrome, Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines, Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines, International Institute for Translational Chinese Medicine, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, PR China. Electronic address: wujinjun@gzucm.edu.cn