Molecular glue neferine induces BAP31 homodimerisation to disrupt endoplasmic reticulum–mitochondria crosstalk for anti‐neuroinflammation in ischaemic stroke
Year: 2025
Type: article
Language: en
Topic: Neuroinflammation and Neurodegeneration Mechanisms
Authors and affiliations:
raw_author_name: Ya‐Xuan Zhu
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Zhuo Yang
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Ling Li
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Ze‐Kun Chen
raw_affiliation_strings: Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Fang‐Fang Zhuo
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Yu‐Hui Wang
raw_affiliation_strings: The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine  Shanghai China
The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China
raw_author_name: Zheng‐Ping Liu
raw_affiliation_strings: Shandong Academy of Pharmaceutical Sciences New Sustained and Controlled Release Formulations and Drug Targeted Delivery System Shandong Engineering Research Center  Jinan China
Shandong Academy of Pharmaceutical Sciences, New Sustained and Controlled Release Formulations and Drug Targeted Delivery System Shandong Engineering Research Center, Jinan, China
raw_author_name: Bo Han
raw_affiliation_strings: School of Pharmacy/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization Shihezi University  Shihezi China
School of Pharmacy/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Shihezi University, Shihezi, China
raw_author_name: Wei Yu
raw_affiliation_strings: School of Pharmacy/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization Shihezi University  Shihezi China
School of Pharmacy/Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Shihezi University, Shihezi, China
raw_author_name: Peng‐Fei Tu
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Tian‐Tian Wei
raw_affiliation_strings: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China
raw_author_name: Hua Wang
raw_affiliation_strings: Department of Oncology The First Affiliated Hospital of Anhui Medical University  Hefei China
Key Laboratory of Anti‐inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education  Hefei China
Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, China
Key Laboratory of Anti-inflammatory and Immune Medicine (Anhui Medical University), Ministry of Education, Hefei, China
raw_author_name: Ke‐Wu Zeng
raw_affiliation_strings: Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences Peking University  Beijing China
State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China