Large-scale integration of omics and electronic health records to identify potential risk protein biomarkers and therapeutic drugs for cancer prevention
Year: 2025
Type: article
Language: en
Topic: Genetic Associations and Epidemiology
Authors and affiliations:
raw_author_name: Qing Li
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada
raw_author_name: Qingyuan Song
raw_affiliation_strings: Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Computer Science, Vanderbilt University, Nashville, TN, USA
raw_author_name: Zhishan Chen
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Jungyoon Choi
raw_affiliation_strings: Division of Oncology and Hematology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan 15355, Korea
raw_author_name: Victor Moreno
raw_affiliation_strings: Oncology Data Analytics Program, Catalan Institute of Oncology (ICO), L'Hospitalet de Llobregat, Barcelona, Spain; Colorectal Cancer Group, ONCOBELL Program, Institut de Recerca Biomedica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain; Department of Clinical Sciences, Faculty of Medicine and Health Sciences and Universitat de Barcelona Institute of Complex Systems (UBICS), University of Barcelona (UB), L'Hospitalet de Llobregat, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain
raw_author_name: Jie Ping
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Wanqing Wen
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Chao Li
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Xiang Shu
raw_affiliation_strings: Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Jun Yan
raw_affiliation_strings: Physiology and Pharmacology, University of Calgary, Calgary, AB, Canada
raw_author_name: Xiao-ou Shu
raw_affiliation_strings: Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Qiuyin Cai
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Jirong Long
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Jeroen R. Huyghe
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
raw_author_name: Rish Pai
raw_affiliation_strings: Mayo Clinic Arizona, Scottsdale, AZ, USA
raw_author_name: Stephen B. Gruber
raw_affiliation_strings: Department of Preventive Medicine & USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
raw_author_name: Yaohua Yang
raw_affiliation_strings: Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
raw_author_name: Graham Casey
raw_affiliation_strings: Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
raw_author_name: Xusheng Wang
raw_affiliation_strings: Department of Genetics, Genomics and Informatics, University of Tennessee Health Science Center, Memphis, TN, USA
raw_author_name: Adetunji T. Toriola
raw_affiliation_strings: Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO, USA
raw_author_name: Li Li
raw_affiliation_strings: Department of Family Medicine, School of Medicine, University of Virginia, Charlottesville, VA, USA
raw_author_name: Bhuminder Singh
raw_affiliation_strings: Epithelial Biology Center and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA
raw_author_name: Ken S. Lau
raw_affiliation_strings: Epithelial Biology Center and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN, USA
raw_author_name: Li Zhou
raw_affiliation_strings: Harvard Medical School, Boston, MA, USA; Division of General Internal Medicine and Primary Care, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA
raw_author_name: Zichen Zhang
raw_affiliation_strings: Department of Biostatistics, the University of Texas MD Anderson, Houston, TX, USA
raw_author_name: Chong Wu
raw_affiliation_strings: Department of Biostatistics, the University of Texas MD Anderson, Houston, TX, USA
raw_author_name: Ulrike Peters
raw_affiliation_strings: Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA, USA
raw_author_name: Wei Zheng
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Quan Long
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada; Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; The Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Department of Mathematics and Statistics, Faculty of Science, University of Calgary, Calgary, AB, Canada
raw_author_name: Zhijun Yin
raw_affiliation_strings: Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Computer Science, Vanderbilt University, Nashville, TN, USA. Electronic address: zhijun.yin.1@vumc.org
raw_author_name: Xingyi Guo
raw_affiliation_strings: Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: xingyi.guo@vumc.org