Pharmacokinetics, safety, and tolerability of nacubactam (OP0595) after intravenous infusion: a randomized, double-blind, placebo-controlled phase I clinical trial in healthy Chinese male subjects
Year: 2025
Type: article
Language: en
Topic: Antibiotic Resistance in Bacteria
Authors and affiliations:
raw_author_name: Hui Qiu
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Tingting Wu
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
Department of Pharmacy, The Third Xiangya Hospital, Central South University, No.138, Tongzipo Road, Changsha, 410013, China
raw_author_name: Lei Diao
raw_affiliation_strings: Shanghai Fosun Pharmaceutical Development Co., Ltd., Shanghai, China
raw_author_name: Nianda Yu
raw_affiliation_strings: Shanghai Fosun Pharmaceutical Development Co., Ltd., Shanghai, China
raw_author_name: Hong Chen
raw_affiliation_strings: Fobeni Healthcom Pharmaceutical Jiangsu Co., Ltd., Jiangsu, China
raw_author_name: Xi Peng
raw_affiliation_strings: Fobeni Healthcom Pharmaceutical Jiangsu Co., Ltd., Jiangsu, China
raw_author_name: Jie Huang
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Jinlian Xie
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Qian Wu
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Shuang Yang
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Xiaoyan Yang
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Long Zeng
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Qi Pei
raw_affiliation_strings: Department of Pharmacy, The Third Xiangya Hospital, Central South University, No.138, Tongzipo Road, Changsha, 410013, China
raw_author_name: Chengxian Guo
raw_affiliation_strings: Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China
raw_author_name: Guoping Yang
raw_affiliation_strings: Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, No.138, Tongzipo Road, Changsha, 410013, China. ygp9880@126.com
Central South University Third Xiangya Hospital Center of Clinical Pharmacology Changsha, Changsha, 410013, Hunan, China. ygp9880@126.com
XiangYa School of Pharmaceutical Sciences, Central South University, Changsha, China. ygp9880@126.com
XiangYa School of Pharmaceutical Sciences, Central South University, Changsha, China
Center for Clinical Pharmacology, The Third Xiangya Hospital, Central South University, No.138, Tongzipo Road, Changsha, 410013, China