Phenotypes in Brugada syndrome with different genotypes triggered by fever or inflammation using gene-edited iPSCs
Year: 2025
Type: article
Language: en
Topic: Cardiac electrophysiology and arrhythmias
Authors and affiliations:
raw_author_name: Yingrui Li
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Lena Rose
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Timo Prädel
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Mandy Kleinsorge
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, 37075, Göttingen, Germany
Stem Cell Unit, Clinic for Cardiology and Pneumology, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Xuehui Fan
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China
raw_author_name: Zenghui Meng
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Chen Yan
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Rui Liu
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Xinhao Lei
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Binyi Zhao
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Guoqiang Yang
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Zhenxing Liao
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Hendrik Dinkel
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Alexandra Viktoria Busley
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, 37075, Göttingen, Germany
Stem Cell Unit, Clinic for Cardiology and Pneumology, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Rujia Zhong
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Feng Zhang
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Qiang Xu
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China
raw_author_name: Lasse Maywald
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Assem Aweimer
raw_affiliation_strings: Department of Cardiology and Angiology, Bergmannsheil University Hospitals, Ruhr University of Bochum, 44789, Bochum, Germany
raw_author_name: Mengying Huang
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Alexander Moscu-Gregor
raw_affiliation_strings: Center for Human Genetics and Laboratory Medicine, Martinsried, Germany
raw_author_name: Nazha Hamdani
raw_affiliation_strings: Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University, Bochum, Germany
Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University, Bochum, Germany
raw_author_name: Luca Schneider
raw_affiliation_strings: Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University, Bochum, Germany
Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University, Bochum, Germany
raw_author_name: Yeweynwuha Zemedi
raw_affiliation_strings: Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University, Bochum, Germany
Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University, Bochum, Germany
raw_author_name: Saltanat Zhazykbayeva
raw_affiliation_strings: Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University, Bochum, Germany
Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University, Bochum, Germany
raw_author_name: Alyssa Hohn
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Zhen Yang
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Lin Qiao
raw_affiliation_strings: First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Andreas Mügge
raw_affiliation_strings: Department of Cardiology and Angiology, Bergmannsheil University Hospitals, Ruhr University of Bochum, 44789, Bochum, Germany
raw_author_name: Lukas Cyganek
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Göttingen, 37075, Göttingen, Germany
Stem Cell Unit, Clinic for Cardiology and Pneumology, University Medical Center Göttingen, 37075, Göttingen, Germany
raw_author_name: Xiaobo Zhou
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany. xiaobo.zhou@medma.uni-heidelberg.de
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. xiaobo.zhou@medma.uni-heidelberg.de
Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China. xiaobo.zhou@medma.uni-heidelberg.de
Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, 646000, Sichuan, China
raw_author_name: Ibrahim Akin
raw_affiliation_strings: DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg-Mannheim, 68167, Mannheim, Germany
First Department of Medicine, Faculty of Medicine Mannheim, University Medical Centre Mannheim (UMM), Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany
raw_author_name: Ibrahim El-Battrawy
raw_affiliation_strings: Department of Cardiology and Angiology, Bergmannsheil University Hospitals, Ruhr University of Bochum, 44789, Bochum, Germany
Department of Cellular and Translational Physiology, Institute of Physiology, Ruhr University, Bochum, Germany
Institut für Forschung und Lehre (IFL), Molecular and Experimental Cardiology, Ruhr University, Bochum, Germany