A TROP2-targeting ADC synergizes with oxidative phosphorylation inhibitor to enhance apoptosis in ESCC by suppressing the PI3K-AKT-mTOR signaling pathway
Year: 2025
Type: article
Language: en
Topic: HER2/EGFR in Cancer Research
Authors and affiliations:
raw_author_name: Xinxin Liu
raw_affiliation_strings: Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
Gannan Branch of National Clinical Research Center for Geriatrics, Ganzhou, 341000, Jiangxi, China
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Jie Liu
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Yi’an Zhou
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Mei Li
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Medical Information Engineering, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Feiqi Wang
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Guanfeng Jiang
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Youban Xiao
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Wenming Cui
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Mingfeng Jiang
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Liang Gu
raw_affiliation_strings: Department of Thoracic Surgery, The First Affiliated Hospital, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Zuxiong Zhang
raw_affiliation_strings: Department of Thoracic Surgery, The First Affiliated Hospital, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Yong Zheng
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China
raw_author_name: Shuyong Zhang
raw_affiliation_strings: Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases (Ministry of Education), Gannan Medical University, Ganzhou, 341000, Jiangxi, China. zsy206@163.com
School of Basic Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China. zsy206@163.com
School of Medical Information Engineering, Gannan Medical University, Ganzhou, 341000, Jiangxi, China. zsy206@163.com
School of Rehabilitation Medicine, Gannan Medical University, Ganzhou, 341000, Jiangxi, China. zsy206@163.com
School of Medical Information Engineering, Gannan Medical University, Ganzhou, 341000, Jiangxi, China