Fixed-duration ibrutinib–venetoclax with MRD-guided ibrutinib–obinutuzumab intensification in first-line chronic lymphocytic leukaemia (HOVON 158/NEXT STEP): primary analysis of a multicentre, open-label, phase 2 trial
Year: 2025
Type: article
Language: en
Topic: Chronic Lymphocytic Leukemia Research
Authors and affiliations:
raw_author_name: Arnon P Kater
raw_affiliation_strings: Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands; Department of Hematology, Cancer Center Amsterdam, Amsterdam, Netherlands; Lymphoma and Myeloma Center Amsterdam and Cancer Center Amsterdam, Amsterdam, Netherlands. Electronic address: a.p.kater@amsterdamumc.nl
raw_author_name: Sabina Kersting
raw_affiliation_strings: Department of Hematology, Haga Hospital, The Hague, Netherlands
raw_author_name: Julie M Dubois
raw_affiliation_strings: Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands; Department of Hematology, Cancer Center Amsterdam, Amsterdam, Netherlands
raw_author_name: Bronno van der Holt
raw_affiliation_strings: HOVON Foundation, Rotterdam, Netherlands; Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
raw_author_name: Caspar da Cunha-Bang
raw_affiliation_strings: Department of Hematology, Rigshospitalet, Copenhagen, Denmark
raw_author_name: Doreen te Raa
raw_affiliation_strings: Department of Internal Medicine, Gelderland Valley Hospital, Ede, Netherlands
raw_author_name: Cecile Idink
raw_affiliation_strings: Department of Internal Medicine, ZorgSaam, Terneuzen, Netherlands
raw_author_name: Fransien de Boer
raw_affiliation_strings: Department of Internal Medicine, Ikazia Hospital, Rotterdam, Netherlands
raw_author_name: Jolanda Droogendijk
raw_affiliation_strings: Department of Internal Medicine, Elisabeth-Tweesteden Hospital, Tilburg, Netherlands
raw_author_name: Koen de Heer
raw_affiliation_strings: Department of Internal Medicine, Flevoziekenhuis, Almere, Netherlands
raw_author_name: Leonie van der Burg
raw_affiliation_strings: Department of Internal Medicine, Antonius Hospital, Sneek, Netherlands
raw_author_name: Marten R Nijziel
raw_affiliation_strings: Department of Internal Medicine, Catharina Hospital, Eindhoven, Netherlands
raw_author_name: Lidwien Tick
raw_affiliation_strings: Department of Internal Medicine, Máxima Medisch Centrum, Eindhoven, Netherlands
raw_author_name: Henriette Levenga
raw_affiliation_strings: Department of Internal Medicine, Groene Hart Hospital, Gouda, Netherlands
raw_author_name: Matthijs Silbermann
raw_affiliation_strings: Department of Internal Medicine, Tergooi Hospital, Hilversum, Netherlands
raw_author_name: Inge Ludwig
raw_affiliation_strings: Department of Hematology, Bernhoven Hospital, Uden, Netherlands
raw_author_name: Aart Beeker
raw_affiliation_strings: Department of Internal Medicine, Spaarne Hospital, Hoofddorp, Netherlands
raw_author_name: Mar Bellido
raw_affiliation_strings: University Medical Center Groningen and University of Groningen, Groningen, Netherlands
raw_author_name: Johan A Dobber
raw_affiliation_strings: Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
raw_author_name: Ludo M Evers
raw_affiliation_strings: Department of Hematology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands
raw_author_name: Anne-Marie van der Kevie-Kersemaekers
raw_affiliation_strings: Department of Human Genetics, Amsterdam University Medical Centers, Amsterdam, Netherlands
raw_author_name: Clemens Mellink
raw_affiliation_strings: Department of Human Genetics, Amsterdam University Medical Centers, Amsterdam, Netherlands
raw_author_name: Ine Meulendijks
raw_affiliation_strings: HOVON Foundation, Rotterdam, Netherlands
raw_author_name: Sonia Cunha
raw_affiliation_strings: HOVON Foundation, Rotterdam, Netherlands
raw_author_name: Martine Abrahamse-Testroote
raw_affiliation_strings: HOVON Foundation, Rotterdam, Netherlands
raw_author_name: Gerben Zwezerijnen
raw_affiliation_strings: Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands
raw_author_name: Josée Zijlstra
raw_affiliation_strings: Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, Amsterdam, Netherlands
raw_author_name: Carsten U Niemann
raw_affiliation_strings: Department of Hematology, Rigshospitalet, Copenhagen, Denmark
raw_author_name: Mark-David Levin
raw_affiliation_strings: Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands