Integrase versus protease inhibitor therapy in advanced HIV disease (LAPTOP): a multicountry, randomised, open-label, non-inferiority trial
Year: 2025
Type: article
Language: en
Topic: HIV/AIDS drug development and treatment
Authors and affiliations:
raw_author_name: Georg M N Behrens
raw_affiliation_strings: Department of Rheumatology and Immunology, Hannover Medical School, Hanover, Germany; Centre for Individualized Infection Medicine, HZI-Hannover Medical School, Hanover, Germany; German Centre for Infection Research Partner Site Hannover-Braunschweig, Hanover, Germany. Electronic address: behrens.georg@mh-hannover.de
raw_author_name: Lambert Assoumou
raw_affiliation_strings: Sorbonne University, Inserm, Pierre Louis Institute of Epidemiology and Public Health, Paris, France
raw_author_name: Geoffroy Liegeon
raw_affiliation_strings: Paris Cité University and Sorbonne University, Paris, France; Department of Infectious and Tropical Diseases, Saint-Louis and Lariboisière Hospital, Paris, France
raw_author_name: Andrea Antinori
raw_affiliation_strings: Clinical and Research Department, IRCCS Lazzaro Spallanzani National Institute for Infectious Diseases, Rome, Italy
raw_author_name: Rafael Micán
raw_affiliation_strings: Infectious Diseases Unit, La Paz University Hospital, Madrid, Spain
raw_author_name: Francesco G Genderini
raw_affiliation_strings: Infectious Diseases Department, Saint-Pierre University Hospital, Brussels, Belgium
raw_author_name: Frank A Post
raw_affiliation_strings: Department of Sexual Health and HIV, Kings College Hospital NHS Foundation Trust, London, UK
raw_author_name: Jürgen K Rockstroh
raw_affiliation_strings: Department of Internal Medicine, University Hospital Bonn, Bonn, Germany
raw_author_name: Lisa Hamzah
raw_affiliation_strings: Department of Clinical Infection, St George's Hospital, London, UK
raw_author_name: Pere Domingo
raw_affiliation_strings: Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
raw_author_name: Adrian Curran
raw_affiliation_strings: Department of Infectious Diseases, Vall d'Hebron University Hospital, Barcelona, Spain
raw_author_name: Montserrat Laguno
raw_affiliation_strings: Infectious Diseases Service, Hospital Clinic de Barcelona, Barcelona, Spain
raw_author_name: Carl Fletcher
raw_affiliation_strings: Research Organisation (KC), London, UK
raw_author_name: Jack Moody
raw_affiliation_strings: Research Organisation (KC), London, UK
raw_author_name: Anton Pozniak
raw_affiliation_strings: Chelsea and Westminster Hospital, London, UK; London School of Hygiene & Tropical Medicine, London, UK
raw_author_name: Georg M N Behrens
raw_affiliation_strings: Department of Rheumatology and Immunology, Hannover Medical School, Hanover, Germany; Centre for Individualized Infection Medicine, HZI-Hannover Medical School, Hanover, Germany; German Centre for Infection Research Partner Site Hannover-Braunschweig, Hanover, Germany. Electronic address: behrens.georg@mh-hannover.de
raw_author_name: Brenda Crabtree
raw_author_name: Nikos Dedes
raw_author_name: Carlo Giaquinto
raw_author_name: Beatriz Grinsztejn
raw_author_name: Esteban Martinez
raw_author_name: Jean-Michel Molina
raw_author_name: Anton Pozniak
raw_affiliation_strings: Chelsea and Westminster Hospital, London, UK; London School of Hygiene & Tropical Medicine, London, UK
raw_author_name: Jürgen K Rockstroh
raw_affiliation_strings: Department of Internal Medicine, University Hospital Bonn, Bonn, Germany
raw_author_name: Francois Venter
raw_author_name: Andrea Antinori
raw_affiliation_strings: Clinical and Research Department, IRCCS Lazzaro Spallanzani National Institute for Infectious Diseases, Rome, Italy
raw_author_name: Cristina Gómez Ayerbe
raw_author_name: Georg M N Behrens
raw_affiliation_strings: Department of Rheumatology and Immunology, Hannover Medical School, Hanover, Germany; Centre for Individualized Infection Medicine, HZI-Hannover Medical School, Hanover, Germany; German Centre for Infection Research Partner Site Hannover-Braunschweig, Hanover, Germany. Electronic address: behrens.georg@mh-hannover.de
raw_author_name: Phil Bright
raw_author_name: Mar Masia Canuto
raw_author_name: Antonella Castagna
raw_author_name: Aoife Cotter
raw_author_name: Alberto Díaz De Santiago
raw_author_name: Pere Domingo
raw_affiliation_strings: Infectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
raw_author_name: Adriàn Curran Fabregas
raw_author_name: Julie Fox
raw_author_name: Lucio Jesus Garcia-Fraile
raw_author_name: Francesco Giovanni Genderini
raw_affiliation_strings: Infectious Diseases Department, Saint-Pierre University Hospital, Brussels, Belgium
raw_author_name: Andrea Giacomelli
raw_author_name: Juan Gonzalez
raw_author_name: Giovanni Guaraldi
raw_author_name: Lisa Hamzah
raw_affiliation_strings: Department of Clinical Infection, St George's Hospital, London, UK
raw_author_name: Elbushra Herieka
raw_author_name: Guillen Sirera Jiménez
raw_author_name: Margaret Anne Johnson
raw_author_name: Christine Katlama
raw_author_name: Stephen Kegg
raw_author_name: Chris Kenyon
raw_author_name: Hernando Knobel
raw_author_name: Karine Lacombe
raw_author_name: Montserrat Laguno
raw_affiliation_strings: Infectious Diseases Service, Hospital Clinic de Barcelona, Barcelona, Spain
raw_author_name: Clara Lehmann
raw_author_name: Pierre Leroy
raw_author_name: Alain Makinson
raw_author_name: Patrick Mallon
raw_author_name: Giulia Marchetti
raw_author_name: Rob Miller
raw_author_name: Jean-Michel Molina
raw_author_name: Roya Movahedi
raw_author_name: Chloe Meave Orkin
raw_author_name: Federico Pulido Ortega
raw_author_name: Jose Luis Casado Osorio
raw_author_name: Patrick Philibert
raw_author_name: Joaquín Portilla
raw_author_name: Frank Alexander Post
raw_affiliation_strings: Department of Sexual Health and HIV, Kings College Hospital NHS Foundation Trust, London, UK
raw_author_name: Francois Raffi
raw_author_name: Jose Ramon Blanco Ramos
raw_author_name: Iain Reeves
raw_author_name: Jürgen Rockstroh
raw_affiliation_strings: Department of Internal Medicine, University Hospital Bonn, Bonn, Germany
raw_author_name: Karen Rogstad
raw_author_name: Maria Saumoy
raw_author_name: Guido Schäfer
raw_author_name: Sarah Schoeman
raw_author_name: Christoph D Spinner
raw_author_name: Christoph Stephan
raw_author_name: Janina Trauth
raw_author_name: Andrew Peter Ustianowski
raw_author_name: Linos Vandekerckhove
raw_author_name: Alan Winston