Modulation of the Apolipoprotein M/S1PR4 Pathway Reduces Podocyte Lipid Overload in Alport Syndrome via Distinct Autophagy and Efflux Mechanisms
Year: 2025
Type: article
Language: en
Topic: Renal Diseases and Glomerulopathies
Authors and affiliations:
raw_author_name: Matthew Tolerico
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Judith Molina
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Arianna Insenga
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Arianna Carrazco
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Rachel Njeim
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Alexis Sloan
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Anthony Griswold
raw_affiliation_strings: Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Makoto Kurano
raw_affiliation_strings: Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan
raw_author_name: Armando Mendez
raw_affiliation_strings: Diabetes Research Institute, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Robin Nathans
raw_affiliation_strings: Centers for Therapeutic Innovation, Pfizer Inc., Cambridge, Massachusetts
raw_author_name: Robin Bolek
raw_affiliation_strings: Centers for Therapeutic Innovation, Pfizer Inc., Cambridge, Massachusetts
raw_author_name: Sandrine Ettou
raw_affiliation_strings: Centers for Therapeutic Innovation, Pfizer Inc., Cambridge, Massachusetts
raw_author_name: Stephen Berasi
raw_affiliation_strings: Centers for Therapeutic Innovation, Pfizer Inc., Cambridge, Massachusetts
raw_author_name: Alessia Fornoni
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida
raw_author_name: Sandra Merscher
raw_affiliation_strings: Katz Family Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Peggy and Harold Katz Family Drug Discovery Center, University of Miami Miller School of Medicine, Miami, Florida