Affinity-matured CD72-targeting nanobody CAR T cells enhance elimination of antigen-low B-cell malignancies
Year: 2025
Type: article
Language: en
Topic: CAR-T cell therapy research
Authors and affiliations:
raw_author_name: Adila Izgutdina
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Tasfia Rashid
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: William C Temple
raw_affiliation_strings: Department of Pediatrics, Division of Allergy, Immunology, and Bone Marrow Transplantation, UCSF Benioff Children’s Hospital, University of California San Francisco, San Francisco, California, USA
Department of Pediatrics, Division of Oncology, UCSF Benioff Children’s Hospital, University of California San Francisco, San Francisco, California, USA
raw_author_name: Sarah Aminov
raw_affiliation_strings: Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, New York, USA
raw_author_name: Bonell Patiño-Escobar
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Sujata Walunj
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Huimin Geng
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Hiroyuki Takamatsu
raw_affiliation_strings: Department of Hematology, Kanazawa University, Kanazawa, Japan
Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Daniel Gil-Alós
raw_affiliation_strings: Department of Hematology, Hospital Universitario 12 de Octubre-Universidad Complutense, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), CIBERONC, Madrid, Spain
Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
Hospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain
raw_author_name: Amrik S Kang
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Emilio Ramos
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Szu-Ying Chen
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Haley Johnson
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Matthew A Nix
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Akul Naik
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Mingcheng Li
raw_affiliation_strings: Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
raw_author_name: Constance M Yuan
raw_affiliation_strings: Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
raw_author_name: Hao-Wei Wang
raw_affiliation_strings: Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
raw_author_name: Srabani Sahu
raw_affiliation_strings: Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, New York, USA
raw_author_name: Rebecca C Larson
raw_affiliation_strings: Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA
Harvard Medical School, Boston, Massachusetts, USA
raw_author_name: Christopher Carpenter
raw_affiliation_strings: Arc Institute, Palo Alto, California, USA
raw_author_name: Fernando Salangsang
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Paul Phojanakong
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Juan Antonio Camara Serrano
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Isa Tariq
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Ons Zakraoui
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Veronica Steri
raw_affiliation_strings: Preclinical Therapeutics Core, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, USA
raw_author_name: Antonio Valeri
raw_affiliation_strings: Department of Hematology, Hospital Universitario 12 de Octubre-Universidad Complutense, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), CIBERONC, Madrid, Spain
Hospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain
raw_author_name: Joaquin Martinez-Lopez
raw_affiliation_strings: Department of Hematology, Hospital Universitario 12 de Octubre-Universidad Complutense, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), CIBERONC, Madrid, Spain
Hospital Universitario 12 de Octubre-Centro Nacional de Investigaciones Oncológicas (H12O-CNIO) Haematological Malignancies Clinical Research Unit, Spanish National Cancer Research Centre, Madrid, Spain
raw_author_name: Marcela V Maus
raw_affiliation_strings: Blood and Marrow Transplant Program, Massachusetts General Hospital, Boston, Massachusetts, USA
Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA
Harvard Medical School, Boston, Massachusetts, USA
raw_author_name: Samir Parekh
raw_affiliation_strings: Department of Medicine, Division of Hematology and Medical Oncology; Department of Oncological Sciences; and Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
raw_author_name: Amit Verma
raw_affiliation_strings: Department of Oncology, Blood Cancer Institute, Albert Einstein College of Medicine, Bronx, New York, USA
raw_author_name: Nirali N Shah
raw_affiliation_strings: Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA
raw_author_name: Arun P Wiita
raw_affiliation_strings: Chan Zuckerberg Biohub, San Francisco, California, USA
Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA
Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
Parker Insitute for Cancer Immunotherapy, San Francisco, California, USA