RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
Year: 2025
Type: article
Language: en
Topic: Protein Kinase Regulation and GTPase Signaling
Authors and affiliations:
raw_author_name: Warapen Treekitkarnmongkol
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Hiroshi Katayama
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. HKatayama@mdanderson.org
Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Deivendran Sankaran
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Signal Transduction and Molecular Pharmacology, Centre for Cancer Drug Discovery, The Institute of Cancer Research London, London, UK
raw_author_name: Mei-Chee Tai
raw_affiliation_strings: Cancer Research Malaysia, Subang Jaya, Malaysia
Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Sanchita Rauth
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA
raw_author_name: Hanxiao Chen
raw_affiliation_strings: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, and Oncode Institute, UMC Utrecht, Utrecht, the Netherlands
raw_author_name: Tristian Nguyen
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Kieko Hara
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Fredrik I. Thege
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Moorthy P. Ponnusamy
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA
raw_author_name: Surinder K. Batra
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA
raw_author_name: Huamin Wang
raw_affiliation_strings: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Ignacio I. Wistuba
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Department of Translational Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tempa, FL, USA
The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA
raw_author_name: Thomas D. Schmittgen
raw_affiliation_strings: Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, FL, USA
raw_author_name: John V. Heymach
raw_affiliation_strings: Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Scott Kopetz
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Tony Hu
raw_affiliation_strings: Center for Cellular and Molecular Diagnostics, Department of Molecular and Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA
raw_author_name: Wantong Yao
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Anirban Maitra
raw_affiliation_strings: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
GI Cancer Center, NYU Langone Health Perlmutter Cancer Center, New York, NY, USA
Sheikh Ahmed Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA
raw_author_name: Subrata Sen
raw_affiliation_strings: Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. ssen@mdanderson.org
The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA. ssen@mdanderson.org
The University of Texas MD Anderson Cancer Center, UTHealth Graduate School of Biomedical Sciences, Houston, TX, USA