Mapping cellular targets of covalent cancer drugs in the entire mammalian body
Year: 2025
Type: article
Language: en
Topic: Click Chemistry and Applications
Authors and affiliations:
raw_author_name: Zhengyuan Pang
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA
raw_author_name: Verina H. Leung
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Cailynn C. Wang
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Ahmadreza Attarpour
raw_affiliation_strings: Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
raw_author_name: Anthony Rinaldi
raw_affiliation_strings: Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada
raw_author_name: Hanbing Shen
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Maria Dolores Moya-Garzon
raw_affiliation_strings: Department of Pathology, Stanford School of Medicine, Stanford, CA, USA; Sarafan ChEM-H, Stanford University, Stanford, CA, USA
raw_author_name: Logan H. Sigua
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Claire Rammel
raw_affiliation_strings: Section of Cardio-Oncology & Immunology, Cardiovascular Research Institute (CVRI), University of California, San Francisco, School of Medicine, San Francisco, CA 94158, USA
raw_author_name: Alexandra Selke
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Christopher Glynn
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Melaina Yender
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Senhan Xu
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
raw_author_name: Javid J. Moslehi
raw_affiliation_strings: Section of Cardio-Oncology & Immunology, Cardiovascular Research Institute (CVRI), University of California, San Francisco, School of Medicine, San Francisco, CA 94158, USA
raw_author_name: Peng Wu
raw_affiliation_strings: Department of Molecular and Cellular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
raw_author_name: Jonathan Z. Long
raw_affiliation_strings: Department of Pathology, Stanford School of Medicine, Stanford, CA, USA; Sarafan ChEM-H, Stanford University, Stanford, CA, USA
raw_author_name: Maged Goubran
raw_affiliation_strings: Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada; Hurvitz Brain Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, Canada
raw_author_name: Benjamin F. Cravatt
raw_affiliation_strings: Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA
raw_author_name: Li Ye
raw_affiliation_strings: Department of Neuroscience, Dorris Neuroscience Center, Scripps Research, San Diego, CA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: liye@scripps.edu