Pharmacological targeting of nuclear factor (erythroid-derived 2)-like 2 (NRF2): a potential strategy to improve the efficacy of oncological photodynamic therapy
Year: 2025
Type: article
Language: en
Topic: Genomics, phytochemicals, and oxidative stress
Authors and affiliations:
raw_author_name: Daniel J. de Klerk
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China; Precision Medicine in Oncology (PrMiO), Department of Pathology, Erasmus MC Cancer Institute, Erasmus Medical Center, Rotterdam, the Netherlands
raw_author_name: Mark J. de Keijzer
raw_affiliation_strings: Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; Membrane Biochemistry and Biophysics, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, the Netherlands
raw_author_name: Leonardo P. Franchi
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Institute of Biological Sciences (ICB 2), Federal University of Goiás (UFG), Goiânia, Goiás, Brazil
raw_author_name: Jiahao Tian
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China; Department of Pathology and Clinical Bioinformatics, Erasmus Medical Center, Rotterdam, the Netherlands
raw_author_name: Maxim A. Gureev
raw_affiliation_strings: School of Computer Science, Physics and Technology, HSE University, Saint Petersburg, Russian Federation
raw_author_name: Yingnan Ge
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China
raw_author_name: Bárbara Mesquita
raw_affiliation_strings: Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands
raw_author_name: Gideon E. Saelman
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands
raw_author_name: Isis Van herteryck
raw_affiliation_strings: Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
raw_author_name: Lionel M. Dias
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China
raw_author_name: Lianne R. de Haan
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands
raw_author_name: Mingjuan Li
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands
raw_author_name: Lenka N.C. Boyd
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands; Laboratory of Medical Oncology, Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands; Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, the Netherlands
raw_author_name: Tessa Y.S. Le Large
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands; Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium; Laboratory of Medical Oncology, Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands
raw_author_name: Elisa Giovannetti
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands; Laboratory of Medical Oncology, Department of Medical Oncology, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands; Cancer Pharmacology Laboratory, Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) Start-Up Unit, Fondazione Pisana per la Scienza, Pisa, Italy
raw_author_name: Geert Kazemier
raw_affiliation_strings: Department of Surgery, Amsterdam University Medical Center (UMC), Vrije Universiteit, Amsterdam, the Netherlands; Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, the Netherlands
raw_author_name: Perry D. Moerland
raw_affiliation_strings: Department of Epidemiology and Data Science, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Yunlei Li
raw_affiliation_strings: Department of Pathology and Clinical Bioinformatics, Erasmus Medical Center, Rotterdam, the Netherlands
raw_author_name: Andrew P. Stubbs
raw_affiliation_strings: Department of Pathology and Clinical Bioinformatics, Erasmus Medical Center, Rotterdam, the Netherlands
raw_author_name: Mathias Devreese
raw_affiliation_strings: Department of Pathobiology, Pharmacology and Zoological Medicine, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
raw_author_name: Yuri B. Porozov
raw_affiliation_strings: School of Computer Science, Physics and Technology, HSE University, Saint Petersburg, Russian Federation; Advitam Laboratory, Belgrade, Serbia
raw_author_name: Joanne Verheij
raw_affiliation_strings: Cancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, the Netherlands; Department of Pathology, Amsterdam University Medical Center (UMC), University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Twan Lammers
raw_affiliation_strings: Department of Nanomedicine and Theranostics, Institute for Experimental Molecular Imaging, Center for Biohyhrid Medical Systems, University Hospital RWTH Aachen, Aachen, Germany
raw_author_name: Yazan S. Khaled
raw_affiliation_strings: Leeds Institute of Medical Research, St. James's University Hospital, Leeds, United Kingdom
raw_author_name: Byron Baron
raw_affiliation_strings: Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta
raw_author_name: Lingfeng Wu
raw_affiliation_strings: Department of Urology, The Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, PR China
raw_author_name: Michal Heger
raw_affiliation_strings: Jiaxing Key Laboratory for Photonanomedicine and Experimental Therapeutics, Department of Pharmaceutics, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China; Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands; Membrane Biochemistry and Biophysics, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, the Netherlands; Applive Research Laboratories, College of Medicine, Jiaxing University, Jiaxing, Zhejiang, PR China. Electronic address: michal.heger@photonanomedicine.com