Multi-modal choroid plexus pathology in aging and Alzheimer’s disease
Year: 2025
Type: article
Language: en
Topic: Cerebrospinal fluid and hydrocephalus
Authors and affiliations:
raw_author_name: Huixin Xu
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Peter Lotfy
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Division of Gastroenterology, Hepatology, and Nutrition, Boston Children’s Hospital, Boston, MA 02115, USA
Graduate Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Benjamin Englert
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
raw_author_name: Jane Oberhauser
raw_affiliation_strings: Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA
Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 94158, USA
raw_author_name: Lillian I.J. Byer
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Jasmin Wihlman
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
HUS Diagnostic Center, Helsinki University Hospital, 00290 Helsinki, Finland
raw_author_name: Kia Colangelo
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
raw_author_name: Serhat V. Okar
raw_affiliation_strings: Translational Neuroradiology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20815, USA
raw_author_name: Ashley Thommana
raw_affiliation_strings: Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
Translational Neuroradiology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20815, USA
raw_author_name: Henri Puttonen
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
HUS Diagnostic Center, Helsinki University Hospital, 00290 Helsinki, Finland
raw_author_name: Mikko I. Mäyränpää
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
HUS Diagnostic Center, Helsinki University Hospital, 00290 Helsinki, Finland
raw_author_name: Jarno Tuimala
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
raw_author_name: Rute Pedrosa
raw_affiliation_strings: Aiforia Technologies Plc., 00150 Helsinki, Finland
raw_author_name: Darshan Kumar
raw_affiliation_strings: Aiforia Technologies Plc., 00150 Helsinki, Finland
raw_author_name: James Francis Haberberger
raw_affiliation_strings: The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA 94305, USA
raw_author_name: Micaiah Emmy Atkins
raw_affiliation_strings: The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA 94305, USA
raw_author_name: Shon Alimukhamedov
raw_affiliation_strings: The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA 94305, USA
raw_author_name: Aja Pragana
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Jordan Benson
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Mary Elizabeth Gabrielle
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
raw_author_name: Anna Dong
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
Harvard College, Harvard University, Cambridge, MA 02138, USA
raw_author_name: Violeta Durán Laforet
raw_affiliation_strings: Department of Neurobiology, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA
raw_author_name: Peter Bor-Chian Lin
raw_affiliation_strings: Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer Disease, Research Center, Washington University, St. Louis, MO 63110, USA
raw_author_name: C. Dirk Keene
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98057, USA
raw_author_name: Caitlin S. Latimer
raw_affiliation_strings: Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, WA, 98057, USA
raw_author_name: Katherine E. Prater
raw_affiliation_strings: Department of Neurology, University of Washington School of Medicine, Seattle, WA, 98057, USA
raw_author_name: David M. Holtzman
raw_affiliation_strings: Department of Neurology, Hope Center for Neurological Disorders, Knight Alzheimer Disease, Research Center, Washington University, St. Louis, MO 63110, USA
raw_author_name: Alina Isakova
raw_affiliation_strings: The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA 94305, USA
raw_author_name: Tony Wyss-Coray
raw_affiliation_strings: Department of Neurology and Neurological Sciences, Stanford University, Stanford, CA 94305, USA
The Phil and Penny Knight Initiative for Brain Resilience, Stanford University, Stanford, CA 94305, USA
raw_author_name: Dorothy P. Schafer
raw_affiliation_strings: Department of Neurobiology, Brudnick Neuropsychiatric Research Institute, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA
raw_author_name: Daniel S. Reich
raw_affiliation_strings: Translational Neuroradiology Section, Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20815, USA
raw_author_name: Terho Lehtimäki
raw_affiliation_strings: Faculty of Medicine and Health Technology, Tampere University, 33100 Tampere, Finland
Fimlab Laboratories Ltd., Wellbeing Services County of Pirkanmaa, 33520 Tampere, Finland
Finnish Cardiovascular Research Center, Tampere University, 33014 Tampere, Finland
raw_author_name: Pekka J. Karhunen
raw_affiliation_strings: Faculty of Medicine and Health Technology, Tampere University, 33100 Tampere, Finland
Fimlab Laboratories Ltd., Wellbeing Services County of Pirkanmaa, 33520 Tampere, Finland
Finnish Cardiovascular Research Center, Tampere University, 33014 Tampere, Finland
raw_author_name: Eloise H. Kok
raw_affiliation_strings: Faculty of Medicine and Health Technology, Tampere University, 33100 Tampere, Finland
Tampere University Hospital, Wellbeing Services County of Pirkanmaa, 33520 Tampere, Finland
raw_author_name: Deidre Jansson
raw_affiliation_strings: Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98108, USA
VISN 20 Northwest Mental Illness Research, Education and Clinical Center, VA Puget Sound Healthcare System, Seattle, WA, USA
raw_author_name: Andrew C. Yang
raw_affiliation_strings: Department of Neurology, University of California, San Francisco, San Francisco, CA, USA
Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA
raw_author_name: Liisa Myllykangas
raw_affiliation_strings: Department of Pathology, University of Helsinki, PO Box 21, 00014 Helsinki, Finland
HUS Diagnostic Center, Helsinki University Hospital, 00290 Helsinki, Finland
raw_author_name: Jose Ordovas-Montanes
raw_affiliation_strings: Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Division of Gastroenterology, Hepatology, and Nutrition, Boston Children’s Hospital, Boston, MA 02115, USA
Harvard Stem Cell Institute, Cambridge, MA 02138, USA
Program in Immunology, Harvard Medical School, Boston, MA 02115, USA
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA
raw_author_name: Maria K. Lehtinen
raw_affiliation_strings: Department of Pathology, Boston Children’s Hospital and Harvard Medical School, Boston, MA 02115, USA
Graduate Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA
Harvard Stem Cell Institute, Cambridge, MA 02138, USA