Colorectal Air–Liquid Interface Organoids Preserve Tumour-Immune Architecture and Reveal Local Treg Expansion After PD-1 Blockade
Year: 2025
Type: article
Language: en
Topic: Cancer Cells and Metastasis
Authors and affiliations:
raw_author_name: Laura Córdoba
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Francisco J. Cueto
raw_affiliation_strings: Department of Medical Oncology, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Ramón Cantero-Cid
raw_affiliation_strings: Digestive Surgery Department, Faculty of Medicine, Universidad Autónoma de Madrid, 28046 Madrid, Spain
Digestive Surgery Service, La Paz University Hospital, 28046 Madrid, Spain
Translational Research and Innovation in Surgery Group, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Rebeca Abad-Moret
raw_affiliation_strings: Digestive Surgery Service, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Esteban Díaz
raw_affiliation_strings: Digestive Surgery Service, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Jaime Álvarez-Benayas
raw_affiliation_strings: ARIES Research Group, Universidad Antonio de Nebrija, 28248 Madrid, Spain
raw_author_name: Jesús Fernández-Felipe
raw_affiliation_strings: Faculty of Health Sciences, Universidad UNIE, 28015 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Jesús Jiménez-Rodríguez
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Daniel Arvelo-Rosario
raw_affiliation_strings: The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Pablo Mata-Martínez
raw_affiliation_strings: Immunomodulation Laboratory, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Marina Arranz-Álvarez
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Yaiza Pedroche-Just
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Sandra Nieto-Torrero
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Jaime Valentín-Quiroga
raw_affiliation_strings: The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Verónica Terrón-Arcos
raw_affiliation_strings: The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Jaime Fernández-Pascual
raw_affiliation_strings: Immunomodulation Laboratory, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Paloma Gómez-Campelo
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Nieves Cubo-Mateo
raw_affiliation_strings: ARIES Research Group, Universidad Antonio de Nebrija, 28248 Madrid, Spain
raw_author_name: Olivia Fernández-Medina
raw_affiliation_strings: Immunomodulation Laboratory, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Laura Hurtado-Navarro
raw_affiliation_strings: Faculty of Health Sciences, Universidad UNIE, 28015 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Gonzalo Sáenz de Santa María
raw_affiliation_strings: The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Julia del Prado-Montero
raw_affiliation_strings: The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Agustín L. Santos
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The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Roberto Lozano-Rodríguez
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Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Carlos del Fresno
raw_affiliation_strings: Immunomodulation Laboratory, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
raw_author_name: Eduardo López-Collazo
raw_affiliation_strings: Biobank Platform, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Biomedical Research Networking Center (CIBER), Respiratory Diseases (CibeRes), 28029 Madrid, Spain
Faculty of Health Sciences, Universidad UNIE, 28015 Madrid, Spain
The Innate Immune Response Group, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain
Tumour Immunology Lab, IdiPAZ, La Paz University Hospital, 28046 Madrid, Spain