TRBC2-targeting antibody–drug conjugates for the treatment of T cell cancers
Year: 2025
Type: article
Language: en
Topic: HER2/EGFR in Cancer Research
Authors and affiliations:
raw_author_name: Jiaxin Ge
raw_affiliation_strings: Division of Hematologic Malignancies and Bone Marrow Transplantation, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Joshua Urban
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Sarah R. DiNapoli
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Bum Seok Lee
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Taha Ahmedna
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Tushar D. Nichakawade
raw_affiliation_strings: Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Brian J. Mog
raw_affiliation_strings: Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Steve Lu
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Xuyang Li
raw_affiliation_strings: Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Nikita Marcou
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Stephanie Glavaris
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Jacqueline Douglass
raw_affiliation_strings: Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Jin Liu
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Maximilian F. Konig
raw_affiliation_strings: Division of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Evangeline Watson
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Maria Popoli
raw_affiliation_strings: Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: J. David Peske
raw_affiliation_strings: Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Sima Rozati
raw_affiliation_strings: Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Cole H. Sterling
raw_affiliation_strings: Division of Hematologic Malignancies and Bone Marrow Transplantation, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Nina Wagner-Johnston
raw_affiliation_strings: Division of Hematologic Malignancies and Bone Marrow Transplantation, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Richard F. Ambinder
raw_affiliation_strings: Division of Hematologic Malignancies and Bone Marrow Transplantation, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Kathy Gabrielson
raw_affiliation_strings: Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Charles G. Mullighan
raw_affiliation_strings: Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Nickolas Papadopoulos
raw_affiliation_strings: Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Chetan Bettegowda
raw_affiliation_strings: Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Drew M. Pardoll
raw_affiliation_strings: Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
raw_author_name: Shibin Zhou
raw_affiliation_strings: Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Surojit Sur
raw_affiliation_strings: Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Kenneth W. Kinzler
raw_affiliation_strings: Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Bert Vogelstein
raw_affiliation_strings: Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Howard Hughes Medical Institute, Chevy Chase, MD, USA
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
raw_author_name: Suman Paul
raw_affiliation_strings: Division of Hematologic Malignancies and Bone Marrow Transplantation, Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, USA. spaul19@jhmi.edu
Ludwig Center and Lustgarten Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA. spaul19@jhmi.edu