Mutant p53 promotes clonal hematopoiesis by generating a chronic inflammatory microenvironment
Year: 2025
Type: article
Language: en
Topic: Acute Myeloid Leukemia Research
Authors and affiliations:
raw_author_name: Sisi Chen
raw_affiliation_strings: Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Precision Research Center for Refractory Diseases, Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Sergio Barajas
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, and
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Sasidhar Vemula
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Yuxia Yang
raw_affiliation_strings: Department of Medical Genetics, School of Basic Medical Sciences, Peking University, Beijing, China
Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Ed Simpson
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Hongyu Gao
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Rudong Li
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Farzaneh Behzadnia
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Sarah C. Nabinger
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: David A. Schmitz
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Hongxia Chen
raw_affiliation_strings: Department of Hematology and Oncology, Chongqing University Three Gorges Hospital, Chongqing, China
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Wenjie Cai
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, and
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Shiyu Xiao
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Ruyue Luo
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Mohammed Abdullahel Amin
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Maegan L. Capitano
raw_affiliation_strings: Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: James P. Ropa
raw_affiliation_strings: Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Aidan Fahey
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Shuyi Zhou
raw_affiliation_strings: Precision Research Center for Refractory Diseases, Department of Hematology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
raw_author_name: Tiffany M. Mays
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Magdalena Sotelo
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Hao Pan
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Sophie K. Hu
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Sophia Veranga
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Moiez Ali
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Maria Shumilina
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Reuben Kapur
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Kehan Ren
raw_affiliation_strings: Department of Pathology and
raw_author_name: Yuzhi Jia
raw_affiliation_strings: Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
raw_author_name: Huiping Liu
raw_affiliation_strings: Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Irum Khan
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Yasmin Abaza
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Jessica K. Altman
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Elizabeth A. Eklund
raw_affiliation_strings: Department of Medicine, Jesse Brown VA Medical Center, Chicago, Illinois, USA
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Lucy A. Godley
raw_affiliation_strings: Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Christine R. Zhang
raw_affiliation_strings: Department of Pathology and
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Peng Ji
raw_affiliation_strings: Department of Pathology and
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Seth L. Masters
raw_affiliation_strings: The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
raw_author_name: Ben A. Croker
raw_affiliation_strings: Department of Pediatrics, University of California San Diego, La Jolla, California, USA
raw_author_name: H. Scott Boswell
raw_affiliation_strings: Department of Medicine and
raw_author_name: George E. Sandusky
raw_affiliation_strings: Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Zhonghua Gao
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, College of Medicine, Pennsylvania State University, Hershey, Pennsylvania, USA
raw_author_name: Lindsey D. Mayo
raw_affiliation_strings: Department of Pediatrics, Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA
raw_author_name: Sharon A. Savage
raw_affiliation_strings: Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
raw_author_name: Stephanie Halene
raw_affiliation_strings: Department of Internal Medicine and Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut, USA
raw_author_name: Yali Dou
raw_affiliation_strings: Department of Medicine, University of Southern California, Los Angeles, California, USA
raw_author_name: Leonidas C. Platanias
raw_affiliation_strings: Department of Medicine, Jesse Brown VA Medical Center, Chicago, Illinois, USA
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Madina Sukhanova
raw_affiliation_strings: Department of Pathology and
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Yunlong Liu
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA
raw_author_name: Omar Abdel-Wahab
raw_affiliation_strings: Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA
raw_author_name: Yan Liu
raw_affiliation_strings: Department of Medical Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA
Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois, USA