IMPROVE-DiCE, a 2-Part, Open-Label, Phase 2a Trial Evaluating the Safety and Effectiveness of Ninerafaxstat in Patients With Cardiometabolic Syndromes
Year: 2025
Type: article
Language: en
Topic: Diabetes Treatment and Management
Authors and affiliations:
raw_author_name: Moritz J. Hundertmark
raw_affiliation_strings: Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland (M.J.H.)
Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: Sarah M. Birkhoelzer
raw_affiliation_strings: Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: Clara Portwood
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raw_author_name: Adrienne G. Siu
raw_affiliation_strings: Department of Physiology, Anatomy and Genetics, Medical Sciences Division, Oxford, United Kingdom (A.G.S., J.G., D.J.T.)
Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: Violet Matthews
raw_affiliation_strings: Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom (V.M., R.S.)
raw_author_name: Andrew J. Lewis
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raw_author_name: James Grist
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Department of Radiology, Oxford University Hospitals NHS Foundations Trust, Oxford, United Kingdom (J.G.)
Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom (J.G.)
Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: Ferenc Mózes
raw_affiliation_strings: Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: John A. Henry
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raw_author_name: Jai Patel
raw_affiliation_strings: Imbria Pharmaceuticals, Boston, MA (J.P., P.C., A.Y.)
raw_author_name: Paul Chamberlin
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raw_author_name: Rizwan Sarwar
raw_affiliation_strings: Experimental Therapeutics, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom (R.S., A.Y.)
Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom (V.M., R.S.)
raw_author_name: Arash Yavari
raw_affiliation_strings: Experimental Therapeutics, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom (R.S., A.Y.)
Imbria Pharmaceuticals, Boston, MA (J.P., P.C., A.Y.)
raw_author_name: Hakim-Moulay Dehbi
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raw_author_name: Prashant Rao
raw_affiliation_strings: CardioVascular Institute, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
raw_author_name: Xu Shi
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Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
raw_author_name: Shuning Zheng
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Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
raw_author_name: Jeremy M. Robbins
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Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
raw_author_name: Robert E. Gerszten
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Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (P.R., X.S., S.Z., J.M.R., R.E.G.)
raw_author_name: Michael P. Frenneaux
raw_affiliation_strings: Imperial College London (M.P.F.)
raw_author_name: Ladislav Valkovič
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Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
raw_author_name: Jack J.J.J. Miller
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raw_author_name: Stefan Neubauer
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Oxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom (M.J.H., S.M.B., C.P., A.G.S., A.J.L., J.G., F.M., J.A.H., L.V., S.N., D.J.T., O.J.R.)
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