Selective B-cell subset depletion underlies increased infection risk in patients with MM treated with anti-BCMA vs anti-GPRC5D bsAbs
Year: 2025
Type: article
Language: en
Topic: Multiple Myeloma Research and Treatments
Authors and affiliations:
raw_author_name: Tomas Jelinek
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
3Sylvester Comprehensive Cancer Center, Myeloma Research Institute, University of Miami, Miami, FL
Universit Hospital Ostrava, Ostrava, Czech Republic
raw_author_name: David Zihala
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
4Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic
Department of Hemato-oncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic, Ostrava, Czech Republic
raw_author_name: Aintzane Zabaleta
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC number CB16/12/00369, Pamplona, Spain, Pamplona, Spain
raw_author_name: Ioannis V. Kostopoulos
raw_affiliation_strings: 6Department of Biology, School of Sciences, National and Kapodistrian University of Athens, Athens, Greece
National and Kapodistrian University of Athens, ATHENS, Greece
raw_author_name: Ondrej Soucek
raw_affiliation_strings: 7Department of Immunology, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic
Faculty of Medicine, University Hospital and Charles University, Hradec Kralove, Hradec Králové, Czech Republic
raw_author_name: Ondrej Venglar
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University of Ostrava, Ostrava, Czech Republic
raw_author_name: Cristina Moreno
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
University of Navarra, Pamplona, Spain
raw_author_name: Despina Fotiou
raw_affiliation_strings: 8Plasma Cell Dyscrasia Unit, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
Alexandra Hospital, National and Kapodistrian University, Athens Medical School, Athens, Greece
raw_author_name: Eva Radova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
raw_author_name: Luis Esteban Tamariz-Amador
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CCUN, CIBER-ONC numbers CB16/12/00369, CB16/12/00489, Pamplona, Pamplona, Spain
raw_author_name: Foteini Theodorakakou
raw_affiliation_strings: 8Plasma Cell Dyscrasia Unit, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
raw_author_name: Ludmila Muronova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University Hospital Ostrava, Ostrava, West Virginia, Czech Republic
raw_author_name: Andrea Manubens
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clinica Universidad de Navarra (CCUN), CIMA Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra (IDISNA), CIBER-ONC, Madrid, Spain
raw_author_name: Ourania Tsitsilonis
raw_affiliation_strings: 6Department of Biology, School of Sciences, National and Kapodistrian University of Athens, Athens, Greece
National and Kapodistrian University of Athens, Athens, Greece
raw_author_name: Tereza Popkova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University Hospital Ostrava, Ostrava-Poruba, Czech Republic
raw_author_name: Carmen Gonzalez
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clinica Universidad de Navarra, Centro de Investigacion Medica Aplicada (CIMA), IDISNA, CIBER-ONC number CB16/12/00369 and CB16/12/00489, Pamplona, Pamplona, Spain
raw_author_name: Anjana Anilkumar Sithara
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
4Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic
University Hospital Ostrava, Ostrava-Poruba, Czech Republic
raw_author_name: Francesco Corrado
raw_affiliation_strings: 9Center for Early Detection and Interception, Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
raw_author_name: Nayda Bidikian
raw_affiliation_strings: 9Center for Early Detection and Interception, Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
raw_author_name: Camila Guerrero
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IDISNA), CIBER-ONC number CB16/12/00369, PAMPLONA, Spain
raw_author_name: Veronika Kapustova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University of Ostrava, Ostrava, Czech Republic
raw_author_name: Daniel Bilek
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
4Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic
Faculty of Science, University of Ostrava, Ostrava, Czech Republic, Ostrava, Czech Republic
raw_author_name: Patrick R. Hagner
raw_affiliation_strings: 10Bristol Myers Squibb, Summit, NJ
Bristol-Myers Squibb, Summit, New Jersey, United States
raw_author_name: Marta Larrayoz
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
CIMA, Pamplona, Spain
raw_author_name: Jose A. Martinez Climent
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain
raw_author_name: Lucie Broskevicova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University Hospital Ostrava, Ostrava-Poruba, Czech Republic
raw_author_name: Jana Mihalyova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
University Hospital Ostrava, Ostrava, Czech Republic
raw_author_name: Maximilian Merz
raw_affiliation_strings: 11Myeloma Service, Memorial Sloan Kettering Cancer Center, New York, NY
MSKCC, New York, United States
raw_author_name: Tereza Sevcikova
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
4Department of Biology and Ecology, Faculty of Science, University of Ostrava, Ostrava, Czech Republic
University of Ostrava, Ostrava, Czech Republic
raw_author_name: Irene M. Ghobrial
raw_affiliation_strings: 9Center for Early Detection and Interception, Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
raw_author_name: Jesus San Miguel
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigación Medica Aplicada (CIMA), Instituto de Investigación, Sanitaria de Navarra (IDISNA, CIBERONC), CIBER-ONC CB16, Pamplona, Navarra, Spain
raw_author_name: Meletios A. Dimopoulos
raw_affiliation_strings: 12Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
13Department of Medicine, Korea University, Seoul, South Korea
Department of Clinical Therapeutics, Plasma cell dyscrasia Unit, National and Kapodistrian University of Athens, Athens, Greece, Greece
raw_author_name: Paula Rodriguez-Otero
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Cancer Center Clínica Universidad de Navarra, Pamplona, Spain
raw_author_name: Jakub Radocha
raw_affiliation_strings: 14Fourth Department of Internal Medicine-Hematology, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic
University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
raw_author_name: Efstathios Kastritis
raw_affiliation_strings: 8Plasma Cell Dyscrasia Unit, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
raw_author_name: Bruno Paiva
raw_affiliation_strings: 5Cancer Center Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada Universidad de Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain
Clinica Universidad de Navarra, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigación Sanitaria de Navarra (IDISNA), CIBERONC (CB16/12/00369), Pamplona, Spain
raw_author_name: Roman Hajek
raw_affiliation_strings: 1Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
2Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
FN Ostrava, Ostrava, Czech Republic