Complete genomes of a multi-generational pedigree to expand studies of genetic and epigenetic inheritance
Year: 2025
Type: article
Language: en
Topic: Genomic variations and chromosomal abnormalities
Authors and affiliations:
raw_author_name: Monika Cechova
raw_affiliation_strings: Faculty of Informatics, Masaryk University, Brno, Czech Republic
UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Tamara A. Potapova
raw_affiliation_strings: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA
raw_author_name: Andreas Rechtsteiner
raw_affiliation_strings: Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA, USA
raw_author_name: Glenn Hickey
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Rebecca Serra Mari
raw_affiliation_strings: Center for Digital Medicine, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Institute for Medical Biometry and Bioinformatics, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
raw_author_name: Mira Mastoras
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Julian Menendez
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Nikol Poláková
raw_affiliation_strings: Faculty of Informatics, Masaryk University, Brno, Czech Republic
raw_author_name: Prajna Hebbar
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Fedor Ryabov
raw_affiliation_strings: International Laboratory of Bioinformatics, HSE University, Moscow, Russia
UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Hailey Loucks
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Aljona Groot
raw_affiliation_strings: Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA, USA
raw_author_name: Tomáš Pavlík
raw_affiliation_strings: Faculty of Informatics, Masaryk University, Brno, Czech Republic
raw_author_name: Mobin Asri
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Shihua Dong
raw_affiliation_strings: Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA
raw_author_name: Stephanie M. Yan
raw_affiliation_strings: Department of Biology, Johns Hopkins University, Baltimore, MD, USA 21218
raw_author_name: Julian K. Lucas
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Steven J. Solar
raw_affiliation_strings: Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
raw_author_name: Matthew Borchers
raw_affiliation_strings: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA
raw_author_name: Mark Mattingly
raw_affiliation_strings: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA
raw_author_name: Sean McKinney
raw_affiliation_strings: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA
raw_author_name: Marie Krátká
raw_affiliation_strings: Faculty of Informatics, Masaryk University, Brno, Czech Republic
National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Kamenice 5, Brno, 62500, Czech Republic
raw_author_name: Catherine Mikhailova
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Ondřej Hanák
raw_affiliation_strings: Faculty of Informatics, Masaryk University, Brno, Czech Republic
raw_author_name: Sohinee Tiffany Saha
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Emily Xu
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Dmitry Antipov
raw_affiliation_strings: Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
raw_author_name: Sergey Koren
raw_affiliation_strings: Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
raw_author_name: Jordan M. Eizenga
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Brandy McNulty
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Joshua M.V. Gardner
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Todd Hillaker
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Ivo Violich
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Christopher Markovic
raw_affiliation_strings: McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA
raw_author_name: Semyon Kruglyak
raw_affiliation_strings: Element Biosciences, San Diego, CA 92121, USA
raw_author_name: Shawn Levy
raw_affiliation_strings: Element Biosciences, San Diego, CA 92121, USA
raw_author_name: Trevor Wolf
raw_affiliation_strings: Element Biosciences, San Diego, CA 92121, USA
raw_author_name: Matthew W. Mitchell
raw_affiliation_strings: Coriell Institute for Medical Research, Camden, NJ 08103, USA
raw_author_name: Laura Scheinfeldt
raw_affiliation_strings: Coriell Institute for Medical Research, Camden, NJ 08103, USA
raw_author_name: Haoyu Cheng
raw_affiliation_strings: Department of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA
raw_author_name: Ivan A. Alexandrov
raw_affiliation_strings: Department of Anatomy and Anthropology & Department of Human Molecular Genetics and Biochemistry, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Rajiv C. McCoy
raw_affiliation_strings: Department of Biology, Johns Hopkins University, Baltimore, MD, USA 21218
raw_author_name: Benedict Paten
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA
raw_author_name: Adam M. Phillippy
raw_affiliation_strings: Genome Informatics Section, Center for Genomics and Data Science Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
raw_author_name: Justin M. Zook
raw_affiliation_strings: Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA
raw_author_name: Jennifer L. Gerton
raw_affiliation_strings: Stowers Institute for Medical Research, Kansas City, MO, 64110, USA
raw_author_name: Robert S. Fulton
raw_affiliation_strings: Element Biosciences, San Diego, CA 92121, USA
raw_author_name: Nathan O. Stitziel
raw_affiliation_strings: Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
raw_author_name: Ting Wang
raw_affiliation_strings: Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA
raw_author_name: Tobias Marschall
raw_affiliation_strings: Center for Digital Medicine, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Institute for Medical Biometry and Bioinformatics, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
raw_author_name: Carol W. Greider
raw_affiliation_strings: Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA, USA
raw_author_name: Karen H. Miga
raw_affiliation_strings: UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA, USA