Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity
Year: 2025
Type: article
Language: en
Topic: Chemokine receptors and signaling
Authors and affiliations:
raw_author_name: Beatrice Zitti
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Florent Duval
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Pratyaksha Wirapati
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Mehdi Hicham
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Yuxuan Xie
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Juhyun Oh
raw_affiliation_strings: Center for Systems Biology, Massachusetts General Brigham and Harvard Medical School, Boston, MA, USA
raw_author_name: Jan Hoelzl
raw_affiliation_strings: Center for Systems Biology, Massachusetts General Brigham and Harvard Medical School, Boston, MA, USA; Department of Medical Oncology, Heidelberg University Hospital, Heidelberg, Germany
raw_author_name: Philippa Meiser
raw_affiliation_strings: Institute of Molecular Immunology, TUM University Hospital, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany
raw_author_name: Marco Varrone
raw_affiliation_strings: AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland
raw_author_name: Hannah M. Peterson
raw_affiliation_strings: Center for Systems Biology, Massachusetts General Brigham and Harvard Medical School, Boston, MA, USA
raw_author_name: Chiara Cianciaruso
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Ruben Bill
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Felix Bayerl
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Evangelia Bolli
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Anne-Gaëlle Goubet
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Máté Kiss
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Sheri McDowell
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Phil Cheng
raw_affiliation_strings: AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Department of Oncology, Geneva University Hospital, Geneva, Switzerland
raw_author_name: Dan Celestini
raw_affiliation_strings: AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Department of Oncology, Geneva University Hospital, Geneva, Switzerland
raw_author_name: Julie Terzic
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Thomas Zwahlen
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland
raw_author_name: Nagham Alouche
raw_affiliation_strings: Department of Immunobiology, University of Lausanne, Lausanne, Switzerland
raw_author_name: Nawel Zouggari
raw_affiliation_strings: Department of Oncology, Geneva University Hospital, Geneva, Switzerland
raw_author_name: David Tarussio
raw_affiliation_strings: Department of Oncology, Center for Experimental Therapeutics, Lausanne University Hospital (CHUV), Lausanne, Switzerland
raw_author_name: Stephanie Tissot
raw_affiliation_strings: Department of Oncology, Center for Experimental Therapeutics, Lausanne University Hospital (CHUV), Lausanne, Switzerland
raw_author_name: Paula Nunes-Hasler
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland
raw_author_name: Mari Mino-Kenudson
raw_affiliation_strings: Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
raw_author_name: Michael Lanuti
raw_affiliation_strings: Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA
raw_author_name: William C. Faquin
raw_affiliation_strings: Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA
raw_author_name: Peter M. Sadow
raw_affiliation_strings: Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Department of Otolaryngology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA
raw_author_name: Jean-Christophe Tille
raw_affiliation_strings: Division of Clinical Pathology, Geneva University Hospitals, Geneva, Switzerland
raw_author_name: Sana Intidhar Labidi-Galy
raw_affiliation_strings: Department of Oncology, Geneva University Hospital, Geneva, Switzerland
raw_author_name: Christopher S. Garris
raw_affiliation_strings: Center for Systems Biology, Massachusetts General Brigham and Harvard Medical School, Boston, MA, USA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
raw_author_name: Stephanie Hugues
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland
raw_author_name: Tatiana V. Petrova
raw_affiliation_strings: Department of Oncology, University of Lausanne, Lausanne, Switzerland; Ludwig Institute for Cancer Research, Lausanne, Switzerland
raw_author_name: Burkhard Ludewig
raw_affiliation_strings: Institute of Immunobiology, Cantonal Hospital, St. Gallen, Switzerland; University Heart Center, University Hospital Zurich, Zurich, Switzerland; Center for Translational and Experimental Cardiology, University Hospital Zurich, Zurich, Switzerland
raw_author_name: Sergio Quezada
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Sanjiv Luther
raw_affiliation_strings: Department of Immunobiology, University of Lausanne, Lausanne, Switzerland
raw_author_name: Thorsten R. Mempel
raw_affiliation_strings: Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, MA, USA
raw_author_name: Giovanni Ciriello
raw_affiliation_strings: AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland
raw_author_name: Sara I. Pai
raw_affiliation_strings: Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Olivier Michielin
raw_affiliation_strings: AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Oncology, Geneva University Hospital, Geneva, Switzerland
raw_author_name: Jan P. Böttcher
raw_affiliation_strings: Institute of Molecular Immunology, TUM University Hospital, School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany; Department of Experimental Immunology, Institute of Immunology, University of Tübingen, Tübingen, Germany; M3 Research Center, University Hospital Tübingen, University of Tübingen, Tübingen, Germany
raw_author_name: Ralph Weissleder
raw_affiliation_strings: Center for Systems Biology, Massachusetts General Brigham and Harvard Medical School, Boston, MA, USA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA; Department of Radiology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
raw_author_name: Mikael J. Pittet
raw_affiliation_strings: Department of Pathology and Immunology, and Center for Translational Oncohaematology Research, University of Geneva, Geneva, Switzerland; AGORA Cancer Research Center, and Swiss Cancer Center Leman, Lausanne, Switzerland; Department of Oncology, Geneva University Hospital, Geneva, Switzerland; Ludwig Institute for Cancer Research, Lausanne, Switzerland. Electronic address: mikael.pittet@unige.ch