Engineered extracellular vesicles-mediated curcumin delivery in brain microenvironment modulating lysosomes, mitochondria, and microglia reprogram for parkinson’s disease therapy
Year: 2025
Type: article
Language: en
Topic: Extracellular vesicles in disease
Authors and affiliations:
raw_author_name: Ming-You Shie
raw_affiliation_strings: Department of Bioinformatics and Medical Engineering, Asia University, Taichung, 413305, Taiwan. eric@mail.cmu.edu.tw
Department of Biomedical Engineering, China Medical University, Taichung, 406040, Taiwan. eric@mail.cmu.edu.tw
Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan. eric@mail.cmu.edu.tw
Xenotransplantation Translational Research Center, China Medical University Hospital, 404327, Taichung, Taiwan. eric@mail.cmu.edu.tw
raw_author_name: Mei-Chih Chen
raw_affiliation_strings: Research and Development Department, Shine Out Bio Technology Co., Ltd, Taichung, 407608, Taiwan
Translational Cell Therapy Center, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Yeh Chen
raw_affiliation_strings: Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, 402202, Taiwan
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan
Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Shi-Wei Huang
raw_affiliation_strings: Translational Cell Therapy Center, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Yen-Hong Lin
raw_affiliation_strings: Department of Biomedical Engineering, China Medical University, Taichung, 406040, Taiwan
Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Min-Hua Yu
raw_affiliation_strings: Institute of Translational Medicine and New Drug Development, China Medical University, Taichung, 406040, Taiwan
Xenotransplantation Translational Research Center, China Medical University Hospital, 404327, Taichung, Taiwan
raw_author_name: Chih-Ming Pan
raw_affiliation_strings: Translational Cell Therapy Center, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Cheng-Yu Chen
raw_affiliation_strings: Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Yi-Wen Chen
raw_affiliation_strings: Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, 402202, Taiwan
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan
Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Ching-Liang Hsieh
raw_affiliation_strings: Chinese Medicine Research Center, China Medical University, Taichung, 406040, Taiwan
Department of Chinese Medicine, China Medical University Hospital, Taichung, 404327, Taiwan
Graduate Institute of Acupuncture Science, China Medical University, Taichung, 406040, Taiwan
raw_author_name: Shao-Chih Chiu
raw_affiliation_strings: Translational Cell Therapy Center, China Medical University Hospital, Taichung, 404327, Taiwan
raw_author_name: Shung-Te Kao
raw_affiliation_strings: School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, 406040, Taiwan
raw_author_name: Jaung-Geng Lin
raw_affiliation_strings: Chinese Medicine Research Center, China Medical University, Taichung, 406040, Taiwan. jglin@mail.cmu.edu.tw
School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, 406040, Taiwan. jglin@mail.cmu.edu.tw
raw_author_name: Der-Yang Cho
raw_affiliation_strings: Department of Neurosurgery, China Medical University Hospital, Taichung, 404327, Taiwan. dycho1212@gmail.com
Graduate Institute of Biomedical Sciences, China Medical University, Taichung, 406040, Taiwan. dycho1212@gmail.com
Research & Development Center for x-Dimensional Extracellular Vesicles, China Medical University Hospital, Taichung, 404327, Taiwan. dycho1212@gmail.com
Translational Cell Therapy Center, China Medical University Hospital, Taichung, 404327, Taiwan. dycho1212@gmail.com
Xenotransplantation Translational Research Center, China Medical University Hospital, 404327, Taichung, Taiwan. dycho1212@gmail.com