Endogenous Osteocyte-Osteoclast Signaling Enables Bone Remodeling, Drug Response, and Cancer Invasion in a Nanoscale Calcified Bone-on-a-Chip Model
Year: 2025
Type: preprint
Language: en
Topic: Bone Metabolism and Diseases
Authors and affiliations:
raw_author_name: Mauricio G.C. Sousa
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health and Science University
raw_author_name: Avathamsa Athirasala
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health and Science University
raw_author_name: Daniela M. Roth
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health and Science University
raw_author_name: Mahshid Hosseini
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Universidade de Campinas (Unicamp)
raw_author_name: Genevieve E. Romanowicz
raw_affiliation_strings: Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA
Oregon Health and Science University
raw_author_name: Rebekka Duhen
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Institute, Oregon Health & Science University, 181 S.W. Sam Jackson Park Road Portland, OR 9729-098
raw_author_name: May Anny A. Fraga
raw_affiliation_strings: Department of Restorative Dentistry, Faculdade de Odontologia de Piracicaba (FOP), Universidade Estadual de Campinas, Piracicaba, São Paulo, Brazil
Oregon Health and Science University
raw_author_name: Sofia M. Vignolo
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
University of Oregon
raw_author_name: Aaron Doe
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health and Science University
raw_author_name: Jinho Lee
raw_affiliation_strings: Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
University of Oregon
raw_author_name: Jonathan V. Nguyen
raw_affiliation_strings: Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health & Science University
raw_author_name: Angela S.P. Lin
raw_affiliation_strings: Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA
University of Oregon
raw_author_name: Cristiane M. Franca
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Oregon Health & Science University
raw_author_name: Robert E. Guldberg
raw_affiliation_strings: Knight Campus for Accelerating Scientific Impact, University of Oregon, Eugene, Oregon, USA
raw_author_name: Luiz E. Bertassoni
raw_affiliation_strings: Cancer Early Detection Advanced Research (CEDAR), Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Department of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA
Department of Oral Rehabilitation and Biosciences, School of Dentistry, Oregon Health & Science University, Portland, Oregon, USA
Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA
Knight Cancer Precision Biofabrication Hub, Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon, USA