Efficacy, safety, pharmacokinetics, immunogenicity, and serum neutralizing activity of AZD7442 (tixagevimab-cilgavimab) in patients hospitalized with COVID-19: long-term results from the DisCoVeRy trial
Year: 2025
Type: article
Language: en
Topic: SARS-CoV-2 and COVID-19 Research
Authors and affiliations:
raw_author_name: Clément R. Massonnaud
raw_affiliation_strings: Département d'Épidémiologie, Biostatistique et Recherche Clinique, AP-HP, Hôpital Bichat Claude-Bernard, F-75018 Paris, France; Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, F-75018 Paris, France. Electronic address: clement.massonnaud@aphp.fr
raw_author_name: Nathan Peiffer-Smadja
raw_affiliation_strings: Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, F-75018 Paris, France; Service de Maladies Infectieuses et Tropicales, AP-HP, Hôpital Bichat Claude-Bernard, F-75018 Paris, France; National Institute for Health Research, Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, London, UK
raw_author_name: Pascal Poignard
raw_affiliation_strings: Groupe de Recherche en Infectiologie Clinique CIC-1406, Inserm-CHUGA-Université Grenoble Alpes, Grenoble, France; University of Grenoble Alpes, CEA, CNRS, Institut de Biologie Structurale (IBS), Grenoble, France; Laboratoire de Virologie, Center Hospitalier Universitaire Grenoble-Alpes, Grenoble, France
raw_author_name: Simon Jamard
raw_affiliation_strings: Service de Maladies Infectieuses Et Tropicales (SMIT), Centre Hospitalier Universitaire de Tours, Tours, France
raw_author_name: François Goehringer
raw_affiliation_strings: Université de Lorraine, CHRU de Nancy, Service des Maladies Infectieuses et Tropicales, Nancy, France
raw_author_name: François Danion
raw_affiliation_strings: Hôpitaux Universitaires de Strasbourg, Département de maladies infectieuses et tropicales, Strasbourg, France
raw_author_name: Jean Reignier
raw_affiliation_strings: CHU de Nantes, Service de Médecine Intensive et Réanimation, Université de Nantes, Nantes, France
raw_author_name: Nathalie de Castro
raw_affiliation_strings: Département des Maladies Infectieuses et Tropicales, GH Saint-Louis/Lariboisière-Fernand Widal, Université de Paris Cité, INSERM U 944, Paris, France
raw_author_name: Denis Garot
raw_affiliation_strings: CHRU Tours, Service de Médecine Intensive Réanimation, Tours, France
raw_author_name: Eva Larranaga Lapique
raw_affiliation_strings: Clinic of Infectious Diseases, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles, Brussels, Belgium
raw_author_name: Karine Lacombe
raw_affiliation_strings: Sorbonne Université, Inserm, Institut Pierre-Louis d'Épidémiologie et de Santé Publique, Paris, France; Service de Maladies Infectieuses et Tropicales, AP-HP, Hôpital Saint-Antoine, F-75012 Paris, France
raw_author_name: Violaine Tolsma
raw_affiliation_strings: Centre Hospitalier Annecy Genevois, Service des Maladies Infectieuses et Tropicales, Annecy, France
raw_author_name: Emmanuel Faure
raw_affiliation_strings: CHU Lille, Service Universitaire de Maladies Infectieuses, Lille, France
raw_author_name: Denis Malvy
raw_affiliation_strings: Department of Infectious Diseases and Tropical Medicine, CHU Bordeaux, Bordeaux, France
raw_author_name: Thérèse Staub
raw_affiliation_strings: Centre Hospitalier de Luxembourg, Service des Maladies Infectieuses, Luxembourg
raw_author_name: Johan Courjon
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raw_author_name: France Cazenave-Roblot
raw_affiliation_strings: Département des Maladies Infectieuses et Tropicales, CHU de Poitiers, INSERM, Poitiers, France
raw_author_name: Anne Ma Dyrhol Riise
raw_affiliation_strings: Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway
raw_author_name: Paul Leturnier
raw_affiliation_strings: Department of Infectious Diseases, Hôtel-Dieu University Hospital, University Hospital of Nantes, Nantes, France
raw_author_name: Guillaume Martin-Blondel
raw_affiliation_strings: CHU de Toulouse, Service des Maladies Infectieuses et Tropicales, Toulouse, France; Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity) INSERM UMR1291-CNRS UMR5051-Université Toulouse III, Toulouse, France
raw_author_name: Claire Roger
raw_affiliation_strings: Department of Anesthesiology, Critical Care Pain, and Emergency Medicine, Nimes University Hospital, Nimes, France
raw_author_name: Karolina Akinosoglou
raw_affiliation_strings: Department of Internal Medicine and Infectious Diseases, University General Hospital of Patras, Patras, Greece
raw_author_name: Vincent Le Moing
raw_affiliation_strings: CHU de Montpellier, Service des Maladies Infectieuses et Tropicales, Montpellier, France
raw_author_name: Lionel Piroth
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raw_author_name: Pierre Sellier
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raw_author_name: Xavier Lescure
raw_affiliation_strings: Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, F-75018 Paris, France; Service de Maladies Infectieuses et Tropicales, AP-HP, Hôpital Bichat Claude-Bernard, F-75018 Paris, France
raw_author_name: Marius Trøseid
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raw_author_name: Philippe Clevenbergh
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raw_author_name: Olav Dalgard
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raw_author_name: Sébastien Gallien
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raw_author_name: Marie Gousseff
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raw_author_name: Paul Loubet
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raw_author_name: Fanny Vardon-Bounes
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raw_author_name: Clotilde Visée
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raw_author_name: Leila Belkhir
raw_affiliation_strings: Department of Internal Medicine and Infectious Diseases, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
raw_author_name: Élisabeth Botelho-Nevers
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raw_author_name: André Cabié
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raw_author_name: Anastasia Kotanidou
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raw_author_name: Fanny Lanternier
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raw_author_name: Elisabeth Rouveix-Nordon
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raw_author_name: Susana Silva
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raw_author_name: Guillaume Thiery
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raw_author_name: Guislaine Carcelain
raw_affiliation_strings: Immunology Department, Robert Debré Hospital, Assistance Publique Hôpitaux de Paris, Paris, France; Université Paris Cité, INSERM U976, Paris, France
raw_author_name: Alpha Diallo
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raw_author_name: Noémie Mercier
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raw_author_name: Vida Terzić
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raw_author_name: Maude Bouscambert-Duchamp
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raw_author_name: Alexandre Gaymard
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raw_author_name: Grégory Destras
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raw_author_name: Laurence Josset
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raw_author_name: Drifa Belhadi
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raw_author_name: Nicolas Billard
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raw_author_name: Jérémie Guedj
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raw_author_name: Thi-Hong-Lien Han
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raw_author_name: Aline Dechanet
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raw_author_name: Claire Fougerou-Leurent
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raw_author_name: Soizic Le Mestre
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raw_author_name: Annabelle Métois
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raw_author_name: Isabelle Bally
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raw_author_name: Sarah Tubiana
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raw_author_name: Joe Eustace
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