Enhanced lysosomal activity prevents infection with PrPSc and the seeding activity of α-synuclein &amp; tau prions
Year: 2025
Type: article
Language: en
Topic: Prion Diseases and Protein Misfolding
Authors and affiliations:
raw_author_name: Robert C.C. Mercer
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Nhat T.T. Le
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Nadia A. Mirza-Romero
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Isabel C. Orbe
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Erin Flaherty
raw_affiliation_strings: Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, USA
raw_author_name: Joseph P. DeFranco
raw_affiliation_strings: Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, USA
raw_author_name: Giada Lavigna
raw_affiliation_strings: Department of Neuroscience, Laboratory of Prion Neurobiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
Laboratory of Prion Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
raw_author_name: Jean R.P. Gatdula
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Douglas G. Fraser
raw_affiliation_strings: Department of Chemistry, Boston University, Boston, Massachusetts, USA
Boston University, Department of Chemistry, Boston, Massachusetts, USA
raw_author_name: Aravind Sundaravadivelu
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Janelle S. Vultaggio
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA
raw_author_name: Aaron B. Beeler
raw_affiliation_strings: Department of Chemistry, Boston University, Boston, Massachusetts, USA
Boston University, Department of Chemistry, Boston, Massachusetts, USA
raw_author_name: Roberto Chiesa
raw_affiliation_strings: Department of Neuroscience, Laboratory of Prion Neurobiology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
Laboratory of Prion Neurobiology, Department of Neuroscience, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy
raw_author_name: Glenn C. Telling
raw_affiliation_strings: Department of Microbiology, Immunology, and Pathology, Prion Research Center, Colorado State University, Fort Collins, Colorado, USA
raw_author_name: David A. Harris
raw_affiliation_strings: Department of Biochemistry & Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA. Electronic address: daharris@bu.edu
Boston University Chobanian & Avedisian School of Medicine, Department of Biochemistry & Cell Biology, Boston, Massachusetts, USA. Electronic address: daharris@bu.edu