Bioavailable human metabolites from TOTUM-448 (plant-based formulation) maintain liver cell functionality in a hyperlipidic context that drives MASLD onset
Year: 2025
Type: article
Language: en
Topic: Liver Disease Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Fabien Wauquier
raw_affiliation_strings: Faculté de Médecine, Clinic'n'Cell SAS, 28 place Henri Dunant, Clermont-Ferrand, 63001, France
raw_author_name: Vivien Chavanelle
raw_affiliation_strings: Valbiotis, 20 rue Henri et Gilberte Goudier, Riom, 63200, France
raw_author_name: Annie Bouchard-Mercier
raw_affiliation_strings: Valbiotis, 20 rue Henri et Gilberte Goudier, Riom, 63200, France
raw_author_name: Line Boutin-Wittrant
raw_affiliation_strings: Faculté de Médecine, Clinic'n'Cell SAS, 28 place Henri Dunant, Clermont-Ferrand, 63001, France
raw_author_name: Yolanda F. Otero
raw_affiliation_strings: Valbiotis, 20 rue Henri et Gilberte Goudier, Riom, 63200, France
raw_author_name: Stéphanie Krisa
raw_affiliation_strings: Université de Bordeaux-INRAE-INP-ISVV, 210 Chem. de Leysotte, Villenave-d'Ornon, 33140, France
raw_author_name: Josep Valls
raw_affiliation_strings: MetaboHUB, Bordeaux Metabolome, 210 Chem. de Leysotte, Villenave-d'Ornon, 33140, France
raw_author_name: Florian Le Joubioux
raw_affiliation_strings: Valbiotis, Zone Industrielle des 4 Chevaliers, Bâtiment 12 F, Rue Paul Vatine, Perigny, 17180, France
raw_author_name: Bruno Pereira
raw_affiliation_strings: Biostat Unit, DRCI, CHU, Clermont-Ferrand, 63000, France
raw_author_name: Véronique Roux
raw_affiliation_strings: CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, Clermont-Ferrand, 63000, France
raw_author_name: Nicolas Macian
raw_affiliation_strings: CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, Clermont-Ferrand, 63000, France
raw_author_name: Gisèle Pickering
raw_affiliation_strings: CIC INSERM 1405/Plateforme d'Investigation Clinique CHU Gabriel Montpied, Clermont-Ferrand, 63000, France
raw_author_name: Véronique Sapone
raw_affiliation_strings: Valbiotis, Zone Industrielle des 4 Chevaliers, Bâtiment 12 F, Rue Paul Vatine, Perigny, 17180, France
raw_author_name: Murielle Cazaubiel
raw_affiliation_strings: Valbiotis, Zone Industrielle des 4 Chevaliers, Bâtiment 12 F, Rue Paul Vatine, Perigny, 17180, France
raw_author_name: Auriane Bron
raw_affiliation_strings: Center for Microbial Ecology and Technology (CMET), Department of Biotechnology, Ghent University, Ghent, Belgium
Digestive Environment and Health, Université Clermont Auvergne, UMR 454 MEDIS UCA-INRAE, Microbiology, Clermont-Ferrand, France
International associated laboratory Host Microbes Interactions in the Human Gut (HOMIGUT), Clermont-Ferrand, France
raw_author_name: Sébastien Peltier
raw_affiliation_strings: Valbiotis, Zone Industrielle des 4 Chevaliers, Bâtiment 12 F, Rue Paul Vatine, Perigny, 17180, France
raw_author_name: Stéphanie Blanquet
raw_affiliation_strings: Digestive Environment and Health, Université Clermont Auvergne, UMR 454 MEDIS UCA-INRAE, Microbiology, Clermont-Ferrand, France
International associated laboratory Host Microbes Interactions in the Human Gut (HOMIGUT), Clermont-Ferrand, France
raw_author_name: Pascal Sirvent
raw_affiliation_strings: Valbiotis, 20 rue Henri et Gilberte Goudier, Riom, 63200, France
raw_author_name: Yohann Wittrant
raw_affiliation_strings: Faculté de Médecine, Clinic'n'Cell SAS, 28 place Henri Dunant, Clermont-Ferrand, 63001, France. yohann.wittrant@inrae.fr
INRAE, UMR 1019, UNH, Clermont-Ferrand, 63000, France. yohann.wittrant@inrae.fr