Convergent mutation trajectories convert functional self-tolerance in IGHV4-34 B cells to genetic tolerance encoded in the antibody
Year: 2025
Type: article
Language: en
Topic: T-cell and B-cell Immunology
Authors and affiliations:
raw_author_name: Christopher J. Jara
raw_affiliation_strings: Garvan Institute of Medical Research
St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales Sydney
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia
raw_author_name: Sherin Zachariah
raw_affiliation_strings: John Curtin School of Medical Research, The Australian National University
John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia
raw_author_name: Katherine J. L. Jackson
raw_affiliation_strings: Garvan Institute of Medical Research
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Timothy J. Peters
raw_affiliation_strings: Garvan Institute of Medical Research
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Etienne Masle-Farquhar
raw_affiliation_strings: Garvan Institute of Medical Research
St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales Sydney
St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Deborah L. Burnett
raw_affiliation_strings: Garvan Institute of Medical Research
School of Biomedical Sciences, University of New South Wales Sydney
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
School of Biomedical Sciences, University of New South Wales Sydney, Sydney, NSW 2052, Australia
raw_author_name: Eric Lam
raw_affiliation_strings: Garvan Institute of Medical Research
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Megan Faulks
raw_affiliation_strings: Garvan Institute of Medical Research
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Amanda Russell
raw_affiliation_strings: Garvan Institute of Medical Research
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Lisa Miosge
raw_affiliation_strings: John Curtin School of Medical Research, The Australian National University
John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia
raw_author_name: Stewart Smith
raw_affiliation_strings: John Curtin School of Medical Research, The Australian National University
John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia
raw_author_name: David C. Tscharke
raw_affiliation_strings: John Curtin School of Medical Research, The Australian National University
John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia
raw_author_name: Robert Brink
raw_affiliation_strings: Garvan Institute of Medical Research
St. Vincent’s Clinical School, Faculty of Medicine, University of New South Wales Sydney
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
St. Vincent's Clinical School, Faculty of Medicine, University of New South Wales Sydney, Sydney, NSW 2052, Australia
raw_author_name: Christopher C. Goodnow
raw_affiliation_strings: Cellular Genomics Futures Institute, University of New South Wales Sydney
Garvan Institute of Medical Research
School of Biomedical Sciences, University of New South Wales Sydney
School of Biomedical Sciences, University of New South Wales Sydney, Sydney, NSW 2052, Australia
Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
raw_author_name: Joanne H. Reed
raw_affiliation_strings: Westmead Institute for Medical Research, University of Sydney
Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia