LabID-base/OpenAlex-Afillation huggingface dataset:
Dietary Pineapple Pomace Complex Improves Growth Performance and Reduces Fecal Odor in Weaned Piglets by Modulating Fecal Microbiota, SCFAs, and Indoles
Year: 2025
Type: article
Language: en
Topic: Pineapple and bromelain studies
Authors and affiliations:
raw_author_name: Shengnan Yu
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Jiahao Jin
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Minglin Zheng
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Fuquan Yin
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Wenchao Liu
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Zhihui Zhao
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
raw_author_name: Liyuan Wang
raw_affiliation_strings: Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518124, China
raw_author_name: Yuxia Chen
raw_affiliation_strings: College of Coastal Agriculture Science, Guangdong Ocean University, Zhanjiang 524088, China
Diagnostic Pathways and Molecular Biomarkers in Colorectal Cancer: Current Evidence and Perspectives in Poland
Year: 2025
Type: article
Language: en
Topic: Colorectal Cancer Screening and Detection
Authors and affiliations:
raw_author_name: Bartosz Bichalski
raw_affiliation_strings: Department of Surgical Nursing and Propaedeutics of Surgery, Faculty of Health Sciences in Katowice, Medical University of Silesia, 41-902 Bytom, Poland
raw_author_name: Magda Bichalska-Lach
raw_affiliation_strings: Department of Surgical Nursing and Propaedeutics of Surgery, Faculty of Health Sciences in Katowice, Medical University of Silesia, 41-902 Bytom, Poland
raw_author_name: Dariusz Waniczek
raw_affiliation_strings: Department of Oncological Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-514 Katowice, Poland
Seasonal Spatial Distribution and Migration Patterns of the Shrimp Parapenaeus fissuroides in the Southern Yellow and East China Seas: Habitat Area Change Under Climate Scenarios
Year: 2025
Type: article
Language: en
Topic: Crustacean biology and ecology
Authors and affiliations:
raw_author_name: Min Xu
raw_affiliation_strings: Key Laboratory of Fisheries Remote Sensing Ministry of Agriculture and Rural Affairs, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
raw_author_name: Yong Liu
raw_affiliation_strings: Key Laboratory of Fisheries Remote Sensing Ministry of Agriculture and Rural Affairs, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
raw_author_name: Yang Xu
raw_affiliation_strings: Key Laboratory of Fisheries Remote Sensing Ministry of Agriculture and Rural Affairs, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
raw_author_name: Haisu Zheng
raw_affiliation_strings: Shanghai Aquatic Wildlife Conservation and Research Center, Shanghai 200080, China
raw_author_name: Jianzhong Ling
raw_affiliation_strings: Key Laboratory of Fisheries Remote Sensing Ministry of Agriculture and Rural Affairs, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
raw_author_name: Huiyu Li
raw_affiliation_strings: Key Laboratory of Fisheries Remote Sensing Ministry of Agriculture and Rural Affairs, East China Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Shanghai 200090, China
Design and performance analysis of bionic trabecular bone scaffold structure based on Voronoi
Year: 2025
Type: article
Language: en
Topic: Cellular and Composite Structures
Authors and affiliations:
raw_author_name: Linlin Liu
raw_affiliation_strings: School of Integrated Circuits, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China
raw_author_name: Xin Wang
raw_affiliation_strings: School of Integrated Circuits, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China. 1102584187@qq.com
School of Integrated Circuits, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China
raw_author_name: Shuxian Wang
raw_affiliation_strings: School of Integrated Circuits, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China
raw_author_name: Juncai Liu
raw_affiliation_strings: Sichuan Provincial Laboratory of Orthopaedic Engineering, Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China
raw_author_name: Jinghong Yang
raw_affiliation_strings: Sichuan Provincial Laboratory of Orthopaedic Engineering, Department of Orthopaedics, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China
raw_author_name: Chen Zhou
raw_affiliation_strings: School of Integrated Circuits, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China
Optimization of Bunkering Logistics at Sea, Taking into Account Cost, Time and Technical Constraints
Year: 2025
Type: article
Language: en
Topic: Vehicle Routing Optimization Methods
Authors and affiliations:
raw_author_name: Dmitry Pervukhin
raw_affiliation_strings: Department of System Analysis and Control, Saint Petersburg Mining University, 199106 Saint Petersburg, Russia
raw_author_name: Semyon Neyrus
raw_affiliation_strings: Department of System Analysis and Control, Saint Petersburg Mining University, 199106 Saint Petersburg, Russia
Comparison of Growth and Water Quality in the Cultivation of Anguilla japonica and Lactuca sativa in Aquaponics with Biofloc and RAS Technologies
Year: 2025
Type: article
Language: en
Topic: Innovations in Aquaponics and Hydroponics Systems
Authors and affiliations:
raw_author_name: Ju-ae Hwang
raw_affiliation_strings: Advanced Aquaculture Research Center, National Institute of Fisheries Science, Changwon 51688, Republic of Korea
raw_author_name: Jun Seong Park
raw_affiliation_strings: Advanced Aquaculture Research Center, National Institute of Fisheries Science, Changwon 51688, Republic of Korea
raw_author_name: Hae Seung Jeong
raw_affiliation_strings: Advanced Aquaculture Research Center, National Institute of Fisheries Science, Changwon 51688, Republic of Korea
Optimizing Fe-Cr-Al Alloy: Microstructure Insights and Mechanical Performance at Different Annealing Temperatures
Year: 2025
Type: article
Language: en
Topic: High-Velocity Impact and Material Behavior
Authors and affiliations:
raw_author_name: Yangli Liu
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
raw_author_name: Yu Zhang
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
raw_author_name: Chengyue Yu
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
raw_author_name: Chuhan Zhang
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
raw_author_name: Zhu Cao
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
raw_author_name: Wang Li
raw_affiliation_strings: Hebei Key Laboratory of Material Near-Net Forming Technology, School of Material Science and Engineering, Hebei University of Science and Technology, Shijiazhuang, 050018, Hebei, China
raw_author_name: Jingyuan Li
raw_affiliation_strings: Beijing Advanced Innovation Center for Materials Genome Engineering, National Key Laboratory of Advanced Stainless Steel, School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, 100083, China
Association between the C-reactive protein–albumin–lymphocyte (CALLY) index and osteoarthritis prevalence: a cross-sectional study of American adults based on NHANES
Year: 2025
Type: article
Language: en
Topic: Inflammatory Biomarkers in Disease Prognosis
Authors and affiliations:
raw_author_name: Linzeng Qi
raw_affiliation_strings: Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China
raw_author_name: Qian Chen
raw_affiliation_strings: Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China
raw_author_name: Yingxia Li
raw_affiliation_strings: Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China
raw_author_name: Yongyuan Guo
raw_affiliation_strings: Department of Orthopaedics, Qilu Hospital of Shandong University, Jinan, China
The effect of seasonal and meteorological factors on suicide rates in the Lithuanian population in 2001–2021: a case‑crossover study
Year: 2025
Type: article
Language: en
Topic: Climate Change and Health Impacts
Authors and affiliations:
raw_author_name: Vidmantas Vaičiulis
raw_affiliation_strings: Department of Environmental and Occupational Medicine, Lithuanian University of Health Sciences, Tilzės St. 18, Kaunas, 47181, Lithuania
Health Research Institute, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, 47181, Lithuania
raw_author_name: Ričardas Radišauskas
raw_affiliation_strings: Department of Environmental and Occupational Medicine, Lithuanian University of Health Sciences, Tilzės St. 18, Kaunas, 47181, Lithuania
Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu Ave. 15, Kaunas, 50162, Lithuania
raw_author_name: Olga Meščeriakova
raw_affiliation_strings: Department of Health Management, Lithuanian University of Health Sciences, Tilzės St. 18, Kaunas, 47181, Lithuania
raw_author_name: Gintarė Kalinienė
raw_affiliation_strings: Department of Environmental and Occupational Medicine, Lithuanian University of Health Sciences, Tilzės St. 18, Kaunas, 47181, Lithuania
Health Research Institute, Lithuanian University of Health Sciences, Tilzes St. 18, Kaunas, 47181, Lithuania
raw_author_name: Donatas Valiukas
raw_affiliation_strings: Lithuanian Hydrometeorological Service, Oršos St. 8, Vilnius, 09300, Lithuania
raw_author_name: Laura Seiduanova
raw_affiliation_strings: Department of Health Politics and Management, Asfendiyarov Kazakh National Medical University, Tole Bi Street 94, Almaty, Kazakhstan, 050000. seyduanova.l@kaznmu.kz
raw_author_name: Akmaral Abikulova
raw_affiliation_strings: Department of Health Politics and Management, Asfendiyarov Kazakh National Medical University, Tole Bi Street 94, Almaty, Kazakhstan, 050000
raw_author_name: Jonė Venclovienė
raw_affiliation_strings: Institute of Cardiology, Lithuanian University of Health Sciences, Sukileliu Ave. 15, Kaunas, 50162, Lithuania
Genome-wide association study to identification of candidate genes influencing key seed traits in Perilla frutescens
Year: 2025
Type: article
Language: en
Topic: Natural Products and Biological Research
Authors and affiliations:
raw_author_name: Me-Sun Kim
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Gi-An Lee
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Jung Yoon Yi
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Yu-Mi Choi
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Myoung-Jae Shin
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Jae-Eun Lee
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Sookyeong Lee
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Kebede Taye Desta
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Eun-Gyeong Kim
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Gyeong Ju Gim
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea
raw_author_name: Eunae Yoo
raw_affiliation_strings: National Agrobiodiversity Center, National Institute of Agricultural Sciences, Rural Development Administration, Jeonju, 54874, Republic of Korea. eung77@korea.kr
Azirine-Based Synthesis of Alkynylpyrroles
Year: 2025
Type: article
Language: en
Topic: Synthesis and Catalytic Reactions
Authors and affiliations:
raw_author_name: Artur E. Taishev
raw_affiliation_strings: Saint Petersburg State University, Institute of Chemistry, 7/9 Universitetskaya Naberezhnaya, St. Petersburg 199034, Russia
raw_author_name: Ekaterina E. Galenko
raw_affiliation_strings: Saint Petersburg State University, Institute of Chemistry, 7/9 Universitetskaya Naberezhnaya, St. Petersburg 199034, Russia
raw_author_name: Mikhail S. Novikov
raw_affiliation_strings: Saint Petersburg State University, Institute of Chemistry, 7/9 Universitetskaya Naberezhnaya, St. Petersburg 199034, Russia
raw_author_name: Alexander F. Khlebnikov
raw_affiliation_strings: Saint Petersburg State University, Institute of Chemistry, 7/9 Universitetskaya Naberezhnaya, St. Petersburg 199034, Russia
Restoring Shallow Lakes by Constructing Pollution Absorption Zone: Practices and Insights
Year: 2025
Type: article
Language: en
Topic: Aquatic Ecosystems and Phytoplankton Dynamics
Authors and affiliations:
raw_author_name: Yihui Zhang
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Jinge Zhu
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Weiping Hu
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Zhaoliang Peng
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Hui Chen
raw_affiliation_strings: Jiangsu Jintan Changdang Lake Tourism Resort Management Office
Jiangsu Jintan Changdang Lake Tourism Resort Management Office, Changzhou 213000, China
raw_author_name: Jiancai Deng
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Jing Luo
raw_affiliation_strings: Key Laboratory of Lake and Watershed Science for Water Security
Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences
Key Laboratory of Lake and Watershed Science for Water Security, Nanjing Institute of Geography and Limnology, Chinese Academy of Sciences, Nanjing 210008, China
raw_author_name: Jian Yang
raw_affiliation_strings: Jiangsu Jintan Changdang Lake Tourism Resort Management Office
Jiangsu Jintan Changdang Lake Tourism Resort Management Office, Changzhou 213000, China
Comparison of the optical and mechanical properties of plastics before and after ethylene oxide sterilization
Year: 2025
Type: article
Language: en
Topic: Polymer Science and PVC
Authors and affiliations:
raw_author_name: Hans de Brouwer
raw_affiliation_strings: SABIC, Technology & Innovation, Bergen op Zoom, the Netherlands
raw_author_name: Muhammad Maqsood
raw_affiliation_strings: SABIC, Technology & Innovation, Geleen, the Netherlands
Comparative Analysis of <scp>mRNA</scp> and <scp>miRNA</scp> Related to Lipid Metabolism in Skeletal Muscle of New Zealand White Rabbit and Yufeng Yellow Rabbit
Year: 2025
Type: article
Language: en
Topic: Rabbits: Nutrition, Reproduction, Health
Authors and affiliations:
raw_author_name: Shuodi Ou
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Yixuan Jiang
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Wenxiang Han
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Huidong Niu
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Taiqing Jia
raw_affiliation_strings: Agricultural and Rural Bureau of Qingfeng County  Puyang Henan China
Agricultural and Rural Bureau of Qingfeng County, Puyang, Henan, China
raw_author_name: Bo Li
raw_affiliation_strings: Agricultural and Rural Bureau of Qingfeng County  Puyang Henan China
Agricultural and Rural Bureau of Qingfeng County, Puyang, Henan, China
raw_author_name: Hanfang Cai
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Yaping Wang
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Zhi Chen
raw_affiliation_strings: College of Animal Science and Technology Yangzhou University  Yangzhou Jiangsu China
College of Animal Science and Technology, Yangzhou University, Yangzhou, Jiangsu, China
raw_author_name: Ming Li
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
raw_author_name: Huifen Xu
raw_affiliation_strings: College of Animal Science and Technology Henan Agricultural University  Zhengzhou China
College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, China
Hierarchical attention graph learning with LLM enhancement for molecular solubility prediction
Year: 2025
Type: article
Language: en
Topic: Machine Learning in Materials Science
Authors and affiliations:
raw_author_name: Yangxin Fan
raw_affiliation_strings: Department of Computer Science, Case Western Reserve University, Cleveland, OH, USA
raw_author_name: Yinghui Wu
raw_affiliation_strings: Department of Computer Science, Case Western Reserve University, Cleveland, OH, USA
raw_author_name: Roger H. French
raw_affiliation_strings: Department of Material Science, Case Western Reserve University, Cleveland, OH, USA
raw_author_name: Danny Perez
raw_affiliation_strings: Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, USA
raw_author_name: Michael G. Taylor
raw_affiliation_strings: Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, USA
raw_author_name: Ping Yang
raw_affiliation_strings: Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM, USA
An LPS-Deficient vaccine candidate with steD deletion confers enhanced protection against homologous and heterologous Salmonella
Year: 2025
Type: article
Language: en
Topic: Salmonella and Campylobacter epidemiology
Authors and affiliations:
raw_author_name: Guodong Zhou
raw_affiliation_strings: College of Agriculture and Biology, Liaocheng University, Shandong, 252059, China
Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, Liaocheng University, Shandong, Liaocheng , 252059, China
raw_author_name: Xinyan Wang
raw_affiliation_strings: College of Agriculture and Biology, Liaocheng University, Shandong, 252059, China
raw_author_name: Hepeng Zhang
raw_affiliation_strings: College of Agriculture and Biology, Liaocheng University, Shandong, 252059, China
raw_author_name: Zhihui Zhang
raw_affiliation_strings: College of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Shandong, Liaocheng , 252059, China
Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, Liaocheng University, Shandong, Liaocheng , 252059, China
raw_author_name: Shengliang Cao
raw_affiliation_strings: College of Agriculture and Biology, Liaocheng University, Shandong, 252059, China
Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, Liaocheng University, Shandong, Liaocheng , 252059, China
raw_author_name: Yubao Li
raw_affiliation_strings: College of Agriculture and Biology, Liaocheng University, Shandong, 252059, China. liyubao@lcu.edu.cn
College of Pharmaceutical Sciences and Food Engineering, Liaocheng University, Shandong, Liaocheng , 252059, China. liyubao@lcu.edu.cn
Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, Liaocheng University, Shandong, Liaocheng , 252059, China. liyubao@lcu.edu.cn
Shandong Key Laboratory of Applied Technology for Protein and Peptide Drugs, Liaocheng University, Shandong, Liaocheng , 252059, China