Cholesterol-metabolic tumor-associated macrophages regulate tumor budding-like cell subpopulation to promote chordoma stemness via BACH1/ANGPTL4/SDC4 axis
Year: 2025
Type: article
Language: en
Topic: Lipid metabolism and disorders
Authors and affiliations:
raw_author_name: Bo-Wen Zheng
raw_affiliation_strings: Department of Orthopedics Surgery, General Hospital of the Central Theater Command , Wuhan,
Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei,
Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang, Hunan,
Musculoskeletal Tumor Center, Peking University People’s Hospital, Peking University , Beijing,
Peking University Musculoskeletal Tumor Center, Peking University People’s Hospital, , Beijing, 100044,
Huazhong University of Science and Technology Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
University of South China Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
raw_author_name: Chao Xia
raw_affiliation_strings: Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang, Hunan,
Huazhong University of Science and Technology Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
University of South China Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
raw_author_name: Wei Huang
raw_affiliation_strings: The First Affiliated Hospital, Health Management Center, Hengyang Medical School, University of South China , Hengyang, Hunan,
University of South China The First Affiliated Hospital, Health Management Center, Hengyang Medical School, , Hengyang, 421001,
raw_author_name: Hua-Qing Niu
raw_affiliation_strings: Department of Ophthalmology, The Second Affiliated Hospital of Zhengzhou University , Zhengzhou,
The Second Affiliated Hospital of Zhengzhou University Department of Ophthalmology, , Zhengzhou, 450014,
raw_author_name: Bang-Min Luo
raw_affiliation_strings: Department of Spinal Surgery, The First People’s Hospital of Chenzhou , Chenzhou,
University of South China Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
Huazhong University of Science and Technology Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
The First People’s Hospital of Chenzhou Department of Spinal Surgery, , Chenzhou, 423000,
raw_author_name: Shen-Quan Liang
raw_affiliation_strings: Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang, Hunan,
University of South China Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
Huazhong University of Science and Technology Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
raw_author_name: Bo-Yv Zheng
raw_affiliation_strings: Department of Orthopedics Surgery, General Hospital of the Central Theater Command , Wuhan,
Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology , Wuhan, Hubei,
Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang, Hunan,
Musculoskeletal Tumor Center, Peking University People’s Hospital, Peking University , Beijing,
General Hospital of the Central Theater Command Department of Orthopedics Surgery, , Wuhan, 430061,
raw_author_name: Ling-Xiang Jiang
raw_affiliation_strings: Department of Radiation Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine , Indianapolis, Indiana,
Indiana University School of Medicine Department of Radiation Oncology, Melvin and Bren Simon Comprehensive Cancer Center, , Indianapolis, Indiana, 46202,
raw_author_name: Peng-Fei Wu
raw_affiliation_strings: Department of Genetics and Endocrinology, National Children’s Medical Center for South Central Region, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University , Guangzhou, Guangdong,
Guangzhou Medical University Department of Genetics and Endocrinology, National Children’s Medical Center for South Central Region, Guangzhou Women and Children’s Medical Center, , Guangzhou, Guangdong, 510623,
raw_author_name: Jing Li
raw_affiliation_strings: Department of Spine Surgery, The Second Xiangya Hospital, Central South University , Changsha,
Central South University Department of Spine Surgery, The Second Xiangya Hospital, , Changsha, 410011,
raw_author_name: Makoto Endo
raw_affiliation_strings: Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University , Fukuoka,
Kyushu University Department of Orthopaedic Surgery, Graduate School of Medical Sciences, , Fukuoka,
raw_author_name: Tao-Lan Zhang
raw_affiliation_strings: Department of Pharmacy, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang,
University of South China Department of Pharmacy, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001,
raw_author_name: Ming-Xiang Zou
raw_affiliation_strings: Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China , Hengyang, Hunan,
University of South China Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,
Huazhong University of Science and Technology Department of Spine Surgery, The First Affiliated Hospital, Hengyang Medical School, , Hengyang, 421001, China; Department of Orthopedics, Wuhan Union Hospital, Tongji Medical College, , Wuhan, 430022, Hubei,