High-throughput <i>in silico</i> screen uncovers key regulators of 3D genome architecture
Year: 2025
Type: article
Language: en
Topic: Genomics and Chromatin Dynamics
Authors and affiliations:
raw_author_name: Jiangshan Bai
raw_affiliation_strings: Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
raw_author_name: Qingji Lyu
raw_affiliation_strings: Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
raw_author_name: Jimin Tan
raw_affiliation_strings: Department of Medicine and Division of Precision Medicine, NYU Grossman School of Medicine, New York, NY, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA
raw_author_name: Robbyn Issner
raw_affiliation_strings: Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
raw_author_name: Bailey Tischer
raw_affiliation_strings: Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
raw_author_name: Hanqing Liu
raw_affiliation_strings: Department of Neurobiology, Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Society of Fellows, Harvard University, Cambridge, MA, USA
raw_author_name: Viraat Goel
raw_affiliation_strings: Department of Biological Engineering and Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
raw_author_name: Xinyu Ling
raw_affiliation_strings: Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA
raw_author_name: Bradley E. Bernstein
raw_affiliation_strings: Department of Cancer Biology, Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
raw_author_name: Aristotelis Tsirigos
raw_affiliation_strings: Department of Medicine and Division of Precision Medicine, NYU Grossman School of Medicine, New York, NY, USA
raw_author_name: Anders S. Hansen
raw_affiliation_strings: Department of Biological Engineering and Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
raw_author_name: Bo Xia
raw_affiliation_strings: Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA
Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY, USA
Society of Fellows, Harvard University, Cambridge, MA, USA