ApoE4 lowers the ptau217 threshold for tau aggregation and spread in an allele dose-dependent manner
Year: 2025
Type: article
Language: en
Topic: Alzheimer's disease research and treatments
Authors and affiliations:
raw_author_name: Anna Steward
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Anna Dewenter
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Fabian Hirsch
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Sebastian N Roemer-Cassiano
raw_affiliation_strings: Department of Neurology, University Hospital LMU , 81377 Munich ,
Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
Max Planck School of Cognition , 04103 Leipzig ,
raw_author_name: Zeyu Zhu
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Amir Dehsarvi
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Davina Biel
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Madleen Klonowski
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Lukas Frontzkowski
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital LMU , 81377 Munich ,
Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
raw_author_name: Carla Palleis
raw_affiliation_strings: Department of Neurology, University Hospital LMU , 81377 Munich ,
German Center for Neurodegenerative Diseases (DZNE) Munich , 81377 Munich ,
Munich Cluster for Systems Neurology (SyNergy) , 81377 Munich ,
raw_author_name: Johannes Gnörich
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital LMU , 81377 Munich ,
raw_author_name: Martin Dichgans
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich , 81377 Munich ,
Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
Munich Cluster for Systems Neurology (SyNergy) , 81377 Munich ,
raw_author_name: Günter Höglinger
raw_affiliation_strings: Department of Neurology, University Hospital LMU , 81377 Munich ,
German Center for Neurodegenerative Diseases (DZNE) Munich , 81377 Munich ,
Munich Cluster for Systems Neurology (SyNergy) , 81377 Munich ,
raw_author_name: Matthias Brendel
raw_affiliation_strings: Department of Nuclear Medicine, University Hospital LMU , 81377 Munich ,
German Center for Neurodegenerative Diseases (DZNE) Munich , 81377 Munich ,
Munich Cluster for Systems Neurology (SyNergy) , 81377 Munich ,
raw_author_name: Nicolai Franzmeier
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital LMU , 81377 Munich ,
Munich Cluster for Systems Neurology (SyNergy) , 81377 Munich ,
The Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, University of Gothenburg , Mölndal and Gothenburg SE 413 90 ,