Celastrol induces cardiotoxicity by directly targeting AMOTL2 and inhibiting YAP1/PGC-1α/TFAM-dependent mitochondrial biogenesis
Year: 2025
Type: article
Language: en
Topic: Cell death mechanisms and regulation
Authors and affiliations:
raw_author_name: Huiying Shang
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
raw_author_name: Hongbo Cheng
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
raw_author_name: Wei Zhou
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China
raw_author_name: Xianglin Tang
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China
raw_author_name: Weiye Han
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China; School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, China
raw_author_name: Xiaotong Zhang
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China; Chinese Materia Medica College, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China
raw_author_name: Chengrong Xiao
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China
raw_author_name: Yehui Gao
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China
Beijing Institute of Radiation Medicine, Beijing, 100850, China. Electronic address: gaoyue@bmi.ac.cn
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China
raw_author_name: Xian Liu
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China. Electronic address: 1539247436@qq.com
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China. Electronic address: 1539247436@qq.com
raw_author_name: Yue Gao
raw_affiliation_strings: Beijing Institute of Radiation Medicine, Beijing, 100850, China
Beijing Institute of Radiation Medicine, Beijing, 100850, China. Electronic address: gaoyue@bmi.ac.cn
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, 100850, China. Electronic address: gaoyue@bmi.ac.cn