Anti-MDA5 monoclonal antibodies from patients with dermatomyositis - B cell characteristics and differential targeting of the helicase domains
Year: 2025
Type: article
Topic: Inflammatory Myopathies and Dermatomyositis
Authors and affiliations:
raw_author_name: Eveline Van Gompel
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium
raw_author_name: Marina Galesic
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Nicolas Delaroque
raw_affiliation_strings: Ligand Development Unit, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Leipzig, Germany
raw_author_name: Karolin Kern
raw_affiliation_strings: Ligand Development Unit, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Leipzig, Germany
raw_author_name: Ragnhild Stålesen
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Antonella Notarnicola
raw_affiliation_strings: Department of Gastroenterology, Dermatology and Rheumatology, Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Deniz Demirdal
raw_affiliation_strings: Department of Gastroenterology, Dermatology and Rheumatology, Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Monika Hansson
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Annika van Vollenhoven
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Edvard Wigren
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Structural Genomics Consortium, Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
raw_author_name: Susanne Gräslund
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Structural Genomics Consortium, Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
raw_author_name: Michael Szardenings
raw_affiliation_strings: Ligand Development Unit, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Leipzig, Germany
raw_author_name: Vivianne Malmström
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Ingrid E Lundberg
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Department of Gastroenterology, Dermatology and Rheumatology, Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Begum Horuluoglu
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Caroline Grönwall
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Karine Chemin
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
raw_author_name: Vijay Joshua
raw_affiliation_strings: Center for Molecular Medicine, Stockholm, Sweden
Division of Immunology and Respiratory Medicine, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden