Utilising multi-modal data-driven network analysis to identify monotherapy and combinational therapy targets in SOX2-dependent squamous cell lung cancer
Year: 2025
Type: article
Language: en
Topic: Bioinformatics and Genomic Networks
Authors and affiliations:
raw_author_name: Woochang Hwang
raw_affiliation_strings: CardiaTec Biosciences LTD, Cambridge, UK
Milner Therapeutics Institute, University of Cambridge, Cambridge, UK
WH and MM - CardiaTec Biosciences, Cambridge, UK; LC - Adaptimmune, Abingdon, UK; RH - Cancer Research Horizons, Cambridge, UK
raw_author_name: Daniel Kottmann
raw_affiliation_strings: Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK
raw_author_name: Wenrui Guo
raw_affiliation_strings: Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK
raw_author_name: Méabh MacMahon
raw_affiliation_strings: CardiaTec Biosciences LTD, Cambridge, UK
Centre for Therapeutics Discovery, LifeArc, Stevenage, UK
Milner Therapeutics Institute, University of Cambridge, Cambridge, UK
raw_author_name: Lucia Correia
raw_affiliation_strings: Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK
WH and MM - CardiaTec Biosciences, Cambridge, UK; LC - Adaptimmune, Abingdon, UK; RH - Cancer Research Horizons, Cambridge, UK
raw_author_name: Sherine Ahmed
raw_affiliation_strings: Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK
raw_author_name: Rebecca Harris
raw_affiliation_strings: Milner Therapeutics Institute, University of Cambridge, Cambridge, UK
WH and MM - CardiaTec Biosciences, Cambridge, UK; LC - Adaptimmune, Abingdon, UK; RH - Cancer Research Horizons, Cambridge, UK
raw_author_name: Frank McCaughan
raw_affiliation_strings: Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK. fm319@cam.ac.uk
Victor Phillip Dahdaleh Heart and Lung Research Institute, Department of Medicine, University of Cambridge, Cambridge, UK
raw_author_name: Namshik Han
raw_affiliation_strings: Cambridge Centre for AI in Medicine, Department of Applied Mathematics and Theoretical Physics, University of Cambridge, Cambridge, UK. nh417@cam.ac.uk
Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. nh417@cam.ac.uk
Center for Nanomedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea. nh417@cam.ac.uk
Department of Nano Biomedical Engineering (NanoBME), Advanced Science Institute, Yonsei University, Seoul, Republic of Korea. nh417@cam.ac.uk
Department of Quantum Information, Institute for Convergence Research and Education in Advanced Technology and Engineering, Yonsei University, Seoul, Republic of Korea. nh417@cam.ac.uk
Milner Therapeutics Institute, University of Cambridge, Cambridge, UK. nh417@cam.ac.uk
Department of Nano Biomedical Engineering (NanoBME), Advanced Science Institute, Yonsei University, Seoul, Republic of Korea
Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK
Center for Nanomedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea
Department of Quantum Information, Institute for Convergence Research and Education in Advanced Technology and Engineering, Yonsei University, Seoul, Republic of Korea