Targeting CTGF overcomes resistance to CSF1R inhibitors by preventing CAF activation in colorectal cancer
Year: 2025
Type: article
Language: en
Topic: Connective Tissue Growth Factor Research
Authors and affiliations:
raw_author_name: Bojun Wang
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Yingjue Li
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Mengde Shi
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Yuanyu Liao
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Yuli Ruan
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Shuling Han
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Yue Ma
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Xin Guan
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Rui Yang
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Tianjiao Dang
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Tong Wu
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Zhuo Chen
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Junyi Duan
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Futing Bai
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China
raw_author_name: Yanqiao Zhang
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China. Electronic address: yanqiaozhang@ems.hrbmu.edu.cn
raw_author_name: Chao Liu
raw_affiliation_strings: Department of Gastrointestinal Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, China; Key Laboratory of Tumor Immunology in Heilongjiang, Harbin, China; Clinical Research Center for Colorectal Cancer in Heilongjiang, Harbin, China; Key Laboratory of Preservation of Human Genetic Resources and Disease Control in China (Harbin Medical University), Ministry of Education, Harbin 150081, China. Electronic address: liuchao@hrbmu.edu.cn