The combination of avutometinib and defactinib in treating recurrent low-grade serous ovarian cancer: a plain language summary of the Phase II clinical trial ENGOT-OV60/GOG-3052/RAMP 201
Year: 2025
Type: article
Language: en
Topic: Ovarian cancer diagnosis and treatment
Authors and affiliations:
raw_author_name: Susana N. Banerjee
raw_affiliation_strings: The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, GTG-UK, London, United Kingdom
raw_author_name: Els Van Nieuwenhuysen
raw_affiliation_strings: University Hospitals Leuven, Leuven Cancer Institute, BGOG, Leuven, Belgium
raw_author_name: Carol Aghajanian
raw_affiliation_strings: Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
Weill Cornell Medical College, New York, NY
raw_author_name: Véronique D’Hondt
raw_affiliation_strings: Institut du Cancer de Montpellier (ICM) Val d’Aurelle Parc Euromedecine, Oncologie Médicale, GINECO, Montpellier, France
Institut du Cancer de Montpellier (ICM) Val d'Aurelle Parc Euromedecine, Oncologie Médicale, GINECO, Montpellier, France
raw_author_name: Bradley J. Monk
raw_affiliation_strings: Florida Cancer Specialists, West Palm Beach, FL
raw_author_name: Andrew Clamp
raw_affiliation_strings: Medical Oncology, The Christie NHS Foundation Trust and University of Manchester, GTG-UK, Manchester, United Kingdom
raw_author_name: Emily Prendergast
raw_affiliation_strings: Gynecologic Oncology, Minnesota Oncology, Minneapolis, MN
raw_author_name: Ana Oaknin
raw_affiliation_strings: Medical Oncology Service, Vall d’Hebron Institute of Oncology, Vall d’Hebron Barcelona Hospital Campus, Barcelona, Spain
Medical Oncology Service, Vall d'Hebron Institute of Oncology, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain
raw_author_name: Kari Ring
raw_affiliation_strings: Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Virginia, Charlottesville, VA
raw_author_name: Nicoletta Colombo
raw_affiliation_strings: European Institute of Oncology, Milan, Italy
Università degli Studi di Milano Bicocca, Bicocca, Italy
raw_author_name: Robert W. Holloway
raw_affiliation_strings: AdventHealth Cancer Institute, Orlando, FL
raw_author_name: Manuel Rodrigues
raw_affiliation_strings: DRUM Team, INSERM U830, Institut Curie, Paris, Franc
Department of Medical Oncology, Institut Curie, Paris, France
raw_author_name: Hye Sook Chon
raw_affiliation_strings: Department of Gynecologic Oncology, H. Lee Moffitt Cancer Center, Tampa, FL
raw_author_name: Charlie Gourley
raw_affiliation_strings: CRUK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
raw_author_name: Alessandro D. Santin
raw_affiliation_strings: Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Gynecologic Oncology, Yale School of Medicine, New Haven, CT
raw_author_name: Premal H. Thaker
raw_affiliation_strings: Division of Gynecologic Oncology, Washington University School of Medicine and Siteman Cancer Center, St. Louis, MO
raw_author_name: Christine Gennigens
raw_affiliation_strings: Department of Medical Oncology, University Hospital of Liège, CHU of Liège, Liège, Belgium
raw_author_name: Gregg Newman
raw_affiliation_strings: Sansum Clinic Healthcare, USO, Santa Barbara, CA
raw_author_name: Erin Salinas
raw_affiliation_strings: Northwest Cancer Specialists, P.C., USO, Portland, OR
raw_author_name: Hagop Youssoufian
raw_affiliation_strings: Verastem Oncology, Boston, MA
raw_author_name: Kathleen N. Moore
raw_affiliation_strings: Stephenson Oklahoma Cancer Center at the University of Oklahoma Health Sciences Center, Oklahoma City, OK
raw_author_name: Stephanie Lustgarten
raw_affiliation_strings: Verastem Oncology, Boston, MA
raw_author_name: David M. O’Malley
raw_affiliation_strings: The Ohio State University, James Comprehensive Cancer Center, Columbus, OH
raw_author_name: Toon Van Gorp
raw_affiliation_strings: University Hospitals Leuven, Leuven Cancer Institute, BGOG, Leuven, Belgium
raw_author_name: Rachel N. Grisham
raw_affiliation_strings: Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
Weill Cornell Medical College, New York, NY