Discovery of an allosteric binding site for anthraquinones at the human P2X4 receptor
Year: 2025
Type: article
Language: en
Topic: Adenosine and Purinergic Signaling
Authors and affiliations:
raw_author_name: Jessica Nagel
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Vigneshwaran Namasivayam
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Stephanie Weinhausen
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Juan Sierra-Marquez
raw_affiliation_strings: Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany
raw_author_name: Younis Baqi
raw_affiliation_strings: Department of Chemistry, College of Science, Sultan Qaboos University, Muscat, Oman
Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Hashem Ali M. Al Musawi
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Aliaa Abdelrahman
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Victoria J. Vaaßen
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Jonathan G. Schlegel
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Lisa Taplick
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Jane Torp
raw_affiliation_strings: Institute of Structural Biology, University of Bonn, Bonn, Germany
raw_author_name: Jan Kubicek
raw_affiliation_strings: Cube Biotech, Monheim, Germany
raw_author_name: Barbara Maertens
raw_affiliation_strings: Cube Biotech, Monheim, Germany
raw_author_name: Matthias Geyer
raw_affiliation_strings: Institute of Structural Biology, University of Bonn, Bonn, Germany
raw_author_name: Tobias Claff
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany
raw_author_name: Annette Nicke
raw_affiliation_strings: Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany
raw_author_name: Gregor Hagelueken
raw_affiliation_strings: Institute of Structural Biology, University of Bonn, Bonn, Germany. hagelueken@uni-bonn.de
Institute of Structural Biology, University of Bonn, Bonn, Germany
raw_author_name: Christa E. Müller
raw_affiliation_strings: Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany. christa.mueller@uni-bonn.de
Pharmaceutical & Medicinal Chemistry, PharmaCenter Bonn, Pharmaceutical Institute, University of Bonn, Bonn, Germany