Distinct proteomic CSF profiles in genetic frontotemporal lobar degeneration
Year: 2025
Type: article
Language: en
Topic: Amyotrophic Lateral Sclerosis Research
Authors and affiliations:
raw_author_name: Julie F H De Houwer
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Elise G Dopper
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Renee van Buuren
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Marijke Stokkel
raw_affiliation_strings: Alzheimer Center Amsterdam, Neurology, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam , Amsterdam 1081 HV ,
Amsterdam Neuroscience , Neurodegeneration, Amsterdam 1081 HV ,
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam , Amsterdam 1081 HV ,
Amsterdam Neuroscience, Neurodegeneration, Amsterdam 1081 HV, The Netherlands
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands
raw_author_name: Liset de Boer
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Tine Swartenbroekx
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Pam A Boesjes
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Ana Rajicic
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Aitana Sogorb-Esteve
raw_affiliation_strings: Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
UK Dementia Research Institute at University College London; WC1N 3BG , London ,
WC1N 3BG, London, UK
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
raw_author_name: Arabella Bouzigues
raw_affiliation_strings: Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
raw_author_name: Lucy L Russell
raw_affiliation_strings: Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
raw_author_name: Phoebe H Foster
raw_affiliation_strings: Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
raw_author_name: Eve Ferry-Bolder
raw_affiliation_strings: Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
raw_author_name: John C van Swieten
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Lize C Jiskoot
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Raquel Sanchez-Valle
raw_affiliation_strings: Alzheimer’s disease and Other Cognitive Disorders Unit, Neurology Service, Hospital Clínic, Institut d’Investigacións Biomèdiques August Pi I Sunyer, University of Barcelona , Barcelona 08036 ,
raw_author_name: Robert Laforce
raw_affiliation_strings: Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques, CHU de Québec, and Faculté de Médecine, Université Laval , QC G1V 4G2 ,
raw_author_name: Caroline Graff
raw_affiliation_strings: Department of Neurobiology, Care Sciences and Society, ; Center for Alzheimer Research, Division of Neurogeriatrics, Bioclinicum, Karolinska Institutet , Solna 171 65 ,
Unit for Hereditary Dementias, Theme Inflammation and Aging, Karolinska University Hospital , Solna 171 76 ,
Unit for Hereditary Dementias, Theme Inflammation and Aging, Karolinska University Hospital, Solna 171 76, Sweden
Department of Neurobiology, Care Sciences and Society,
raw_author_name: Daniela Galimberti
raw_affiliation_strings: Department of Biomedical, Surgical and Dental Sciences, University of Milan , Milan 20122 ,
Neurodegenerative Diseases Unit, Fondazione IRCCS Ospedale Maggiore Policlinico , Milan 20122 ,
Neurodegenerative Diseases Unit, Fondazione IRCCS Ospedale Maggiore Policlinico, Milan 20122, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan 20122, Italy
raw_author_name: Rik Vandenberghe
raw_affiliation_strings: Laboratory for Cognitive Neurology, Department of Neurosciences , KU Leuven, Leuven 3000 ,
Leuven Brain Institute , KU Leuven, Leuven 3000 ,
Neurology Service, University Hospitals Leuven , Leuven 3000 ,
Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Leuven 3000, Belgium
Leuven Brain Institute, KU Leuven, Leuven 3000, Belgium
raw_author_name: Alexandre de Mendonça
raw_affiliation_strings: Faculty of Medicine, University of Lisbon , Lisbon 1649-028 ,
Faculty of Medicine, University of Lisbon, Lisbon 1649-028, Portugal
raw_author_name: Pietro Tiraboschi
raw_affiliation_strings: Fondazione IRCCS Istituto Neurologico Carlo Besta , Milano 20133 ,
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano 20133, Italy
raw_author_name: Isabel Santana
raw_affiliation_strings: Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra , Coimbra 3004-504 ,
University Hospital of Coimbra (HUC), Neurology Service, Faculty of Medicine, University of Coimbra , Coimbra 3004-531 ,
University Hospital of Coimbra (HUC), Neurology Service, Faculty of Medicine, University of Coimbra, Coimbra 3004-531, Portugal
raw_author_name: Alexander Gerhard
raw_affiliation_strings: Department of Nuclear Medicine, Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen , Essen 45147 ,
Division of Psychology Communication and Human Neuroscience, Wolfson Molecular Imaging Centre, University of Manchester , Manchester M20 3LJ ,
Department of Nuclear Medicine, Center for Translational Neuro- and Behavioral Sciences, University Medicine Essen, Essen 45147, Germany
Division of Psychology Communication and Human Neuroscience, Wolfson Molecular Imaging Centre, University of Manchester, Manchester M20 3LJ, UK
raw_author_name: Johannes Levin
raw_affiliation_strings: Department of Neurology, Ludwig-Maximilians Universität München , Munich 80802 ,
German Center for Neurodegenerative Diseases (DZNE) , Munich 81377 ,
Munich Cluster of Systems Neurology (SyNergy) , Munich 81377 ,
German Center for Neurodegenerative Diseases (DZNE), Munich 81377, Germany
raw_author_name: Benedetta Nacmias
raw_affiliation_strings: Department of Neurofarba, University of Florence , Florence 50139 ,
IRCCS Fondazione Don Carlo Gnocchi , Florence 50139 ,
IRCCS Fondazione Don Carlo Gnocchi, Florence 50139, Italy
Department of Neurofarba, University of Florence, Florence 50139, Italy
raw_author_name: Markus Otto
raw_affiliation_strings: Department of Neurology, University of Ulm , Ulm 45 89081 ,
Department of Neurology, University of Ulm, Ulm 45 89081, Germany
raw_author_name: Maxime Bertoux
raw_affiliation_strings: Lille Neuroscience & Cognition U1172, University of Lille , Inserm, CHU Lille 59000 ,
Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille 59000, France
raw_author_name: Thibaud Lebouvier
raw_affiliation_strings: Lille Neuroscience & Cognition U1172, University of Lille , Inserm, CHU Lille 59000 ,
Lille Neuroscience & Cognition U1172, University of Lille, Inserm, CHU Lille 59000, France
raw_author_name: Simon Ducharme
raw_affiliation_strings: Douglas Mental Health University Institute, Department of Psychiatry, McGill University , Montreal, Québec H4H 1R3 ,
McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University , Montreal, Québec H4H 1R3 ,
raw_author_name: Chris R Butler
raw_affiliation_strings: Department of Brain Sciences, Imperial College London , London SW7 2AZ ,
Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford , Oxford OX3 7JX ,
Department of Brain Sciences, Imperial College London, London SW7 2AZ, UK
Nuffield Department of Clinical Neurosciences, Medical Sciences Division, University of Oxford, Oxford OX3 7JX, UK
raw_author_name: Isabelle Le Ber
raw_affiliation_strings: Centre de référence des démences rares ou précoces, IM2A, Département de Neurologie, AP-HP - Hôpital Pitié-Salpêtrière , Paris 75013 ,
Département de Neurologie, AP-HP - Hôpital Pitié-Salpêtrière , Paris 75013 ,
Sorbonne Université, Paris Brain Institute – Institut du Cerveau – ICM , Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris 75013 ,
raw_author_name: Elizabeth Finger
raw_affiliation_strings: Department of Clinical Neurological Sciences, University of Western Ontario , London, ON N6A 3K7 ,
Department of Clinical Neurological Sciences, University of Western Ontario, London, ON N6A 3K7, Canada
raw_author_name: Maria Carmela Tartaglia
raw_affiliation_strings: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto , Toronto, ON M5G 1E8 ,
Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON M5G 1E8, Canada
raw_author_name: Mario Masellis
raw_affiliation_strings: Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto , Toronto, ON M4N 3M5 ,
Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, University of Toronto, Toronto, ON M4N 3M5, Canada
raw_author_name: James B Rowe
raw_affiliation_strings: Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge , Cambridge CB2 3EB ,
Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, Cambridge CB2 3EB, UK
raw_author_name: Matthis Synofzik
raw_affiliation_strings: Center for Neurodegenerative Diseases (DZNE) , Tübingen 72076 ,
Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen , Tübingen 72076 ,
raw_author_name: Fermin Moreno
raw_affiliation_strings: Biogipuzkoa Health Research Institute, Neurosciences Area, Group of Neurodegenerative Diseases , 20014 San Sebastian ,
Center for Biomedical Research in Neurodegenerative Disease (CIBERNED), Carlos III Health Institute , Madrid 28029 ,
Cognitive Disorders Unit, Department of Neurology, Hospital Universitario Donostia , 20014, San Sebastian ,
Center for Biomedical Research in Neurodegenerative Disease (CIBERNED), Carlos III Health Institute, Madrid 28029, Spain
Cognitive Disorders Unit, Department of Neurology, Hospital Universitario Donostia, 20014, San Sebastian, Spain
Biogipuzkoa Health Research Institute, Neurosciences Area, Group of Neurodegenerative Diseases, 20014 San Sebastian, Spain
raw_author_name: Barbara Borroni
raw_affiliation_strings: Department of Clinical and Experimental Sciences, University of Brescia , Brescia 15-25121 ,
Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli , Brescia 15-25125 ,
Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia 15-25125, Italy
Department of Clinical and Experimental Sciences, University of Brescia, Brescia 15-25121, Italy
raw_author_name: Henrik Zetterberg
raw_affiliation_strings: Centre for Brain Research, Indian Institute of Science , Bangalore 560012 ,
Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital; Mölndal 413 45 ,
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London , London WC1N 3AR ,
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg; Mölndal 405 30 ,
Hong Kong Center for Neurodegenerative Diseases , Clear Water Bay; Hong Kong 999 077 ,
Wisconsin Alzheimer’s Disease Research Center, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison; Madison , WI 53726 ,
Madison, WI 53726, USA
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, London WC1N 3AR, UK
Centre for Brain Research, Indian Institute of Science, Bangalore 560012, India
raw_author_name: Jonathan D Rohrer
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands
raw_author_name: Betty M Tijms
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Amsterdam Neuroscience , Neurodegeneration, Amsterdam 1081 HV ,
Amsterdam Neuroscience, Neurodegeneration, Amsterdam 1081 HV, The Netherlands
Alzheimer Center Amsterdam, Neurology, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands
raw_author_name: Yolande A L Pijnenburg
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Amsterdam Neuroscience , Neurodegeneration, Amsterdam 1081 HV ,
Alzheimer Center Amsterdam, Neurology, Amsterdam UMC location VUmc, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands
Amsterdam Neuroscience, Neurodegeneration, Amsterdam 1081 HV, The Netherlands
raw_author_name: Charlotte Teunissen
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Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam , Amsterdam 1081 HV ,
Amsterdam Neuroscience, Neurodegeneration, Amsterdam 1081 HV, The Netherlands
Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands
raw_author_name: Harro Seelaar
raw_affiliation_strings: Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre , Rotterdam 3015 GD ,
Department of Neurology and Alzheimer Centre, Erasmus MC University Medical Centre, Rotterdam 3015 GD, The Netherlands