A Novel Metal‐Phenolic‐Protein Hybrid Nanoparticles With Precise Delivery and Enhanced Penetration Effect for tPA Targeted Thrombolysis and Reduced Hemorrhagic Risk
Year: 2025
Type: article
Language: en
Topic: Protease and Inhibitor Mechanisms
Authors and affiliations:
raw_author_name: Xinyi Zhao
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Wendie Wang
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Jing Shi
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Qi Zhou
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Zitong Zhao
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Chenyang Li
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Precision Medicine Research Center School of Pharmacy Binzhou Medical University Yantai Shandong Province China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
Precision Medicine Research Center, School of Pharmacy, Binzhou Medical University, Yantai, Shandong Province, China
raw_author_name: Mingshuai Tang
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics School of Pharmacy Heilongjiang University of Chinese Medicine Harbin Heilongjiang Province China
Department of Pharmaceutics, School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang Province, China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China
raw_author_name: Jing Wang
raw_affiliation_strings: Department of Nuclear Medicine and PET Center The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang Province China
Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University Hangzhou Zhejiang Province China
Key Laboratory of Medical Molecular Imaging of Zhejiang Province Hangzhou Zhejiang Province China
Zhejiang Cancer Hospital Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences Hangzhou Zhejiang Province China
Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University, Hangzhou, Zhejiang Province, China
Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang Province, China
Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, Zhejiang Province, China
raw_author_name: Jing Zhao
raw_affiliation_strings: Department of Neurology Minhang Hospital Fudan University Shanghai China
Institute of Healthy Yangtze River Delta Shanghai Jiao Tong University  Shanghai China
Institute of Healthy Yangtze River Delta, Shanghai Jiao Tong University, Shanghai, China
Department of Neurology, Minhang Hospital, Fudan University, Shanghai, China
raw_author_name: Hong Zhang
raw_affiliation_strings: Department of Nuclear Medicine and PET Center The Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang Province China
Institute of Nuclear Medicine and Molecular Imaging of Zhejiang University Hangzhou Zhejiang Province China
Key Laboratory for Biomedical Engineering of Ministry of Education Zhejiang University Hangzhou Zhejiang Province China
Key Laboratory of Medical Molecular Imaging of Zhejiang Province Hangzhou Zhejiang Province China
Zhejiang Cancer Hospital Hangzhou Institute of Medicine (HIM) Chinese Academy of Sciences Hangzhou Zhejiang Province China
Department of Nuclear Medicine and PET Center, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China
Key Laboratory of Medical Molecular Imaging of Zhejiang Province, Hangzhou, Zhejiang Province, China
Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou, Zhejiang Province, China
Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang Province, China
raw_author_name: Jing Qin
raw_affiliation_strings: Department of Pharmaceutics School of Pharmaceutical Sciences Fudan University &amp; Key Laboratory of Smart Drug Delivery Ministry of Education &amp; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers Shanghai China
Department of Pharmaceutics, School of Pharmaceutical Sciences, Fudan University & Key Laboratory of Smart Drug Delivery, Ministry of Education & National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China