Structures of tRNA-bound CRISPR-Cas13 reveal universal HEPN RNase mechanisms
Year: 2025
Type: article
Topic: RNA and protein synthesis mechanisms
Authors and affiliations:
raw_author_name: Roland W. Calvert
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Brooke K. Hayes
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Her Xiang Chai
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Yongyi Peng
raw_affiliation_strings: Department of Microbiology, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Cheng Huang
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
RNA Mass Spectrometry Platform, Monash Proteomics & Metabolomics Platform, Monash University; Clayton, Victoria, Australia
raw_author_name: Hariprasad Venugopal
raw_affiliation_strings: Ramaciotti Centre for Cryo-Electron Microscopy, Monash University; Clayton, VIC 3800, Australia
raw_author_name: Cyntia Taveneau
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Jovita D’Silva
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Joseph Rosenbluh
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Cancer Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
Functional Genomics Platform, Monash University; Melbourne, VIC, Australia
raw_author_name: Chen Davidovich
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
RNA Mass Spectrometry Platform, Monash Proteomics & Metabolomics Platform, Monash University; Clayton, Victoria, Australia
raw_author_name: Chris Greening
raw_affiliation_strings: ARC Research Hub for Carbon Utilisation and Recycling, Monash University; Clayton, Victoria, Australia
Department of Microbiology, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
Securing Antarctica’s Environmental Future, Monash University; Clayton, Victoria, Australia
raw_author_name: Rebecca S. Bamert
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia
raw_author_name: Gavin J. Knott
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, Infection Program, Biomedicine Discovery Institute, Monash University; Clayton, Victoria, Australia