DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance
Year: 2025
Type: article
Language: en
Topic: RNA Research and Splicing
Authors and affiliations:
raw_author_name: Hongjie Bi
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Pathology, Harbin Medical University, Harbin, China
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Wei Li
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Lili Ren
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Pathology, Harbin Medical University, Harbin, China
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Honghai Zhang
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Lei Dong
raw_affiliation_strings: Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
Quantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, UT Southwestern Medical Center, Dallas, TX, USA
raw_author_name: Anthony Chan
raw_affiliation_strings: Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
Division of Epigenetic and Transcriptional Engineering, Beckman Research Institute, City of Hope, Duarte, CA, USA
Laboratory of Gene Editing and Cellular Engineering, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA
raw_author_name: Xueer Wang
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Lu Yang
raw_affiliation_strings: Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
Division of Epigenetic and Transcriptional Engineering, Beckman Research Institute, City of Hope, Duarte, CA, USA
raw_author_name: Xiaoxu Zhang
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Meilin Xue
raw_affiliation_strings: Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Hanjun Qin
raw_affiliation_strings: The Integrative Genomics Core, Beckman Research Institute of City of Hope, Duarte, CA, USA
raw_author_name: Xiwei Wu
raw_affiliation_strings: The Integrative Genomics Core, Beckman Research Institute of City of Hope, Duarte, CA, USA
raw_author_name: Johanna Ten Hoeve-Scott
raw_affiliation_strings: UCLA Metabolomics Center, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA, USA
raw_author_name: Bin Zhang
raw_affiliation_strings: Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope Medical Center and Beckman Research Institute, Duarte, CA, USA
raw_author_name: Ling Li
raw_affiliation_strings: Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, City of Hope Medical Center and Beckman Research Institute, Duarte, CA, USA
raw_author_name: Mark Wunderlich
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA
raw_author_name: James C. Mulloy
raw_affiliation_strings: Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA
raw_author_name: Steven T. Rosen
raw_affiliation_strings: Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, USA
raw_author_name: Jianjun Chen
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA
raw_author_name: Xiaobo Li
raw_affiliation_strings: Department of Pathology, Harbin Medical University, Harbin, China. lixiaobo@ems.hrbmu.edu.cn
Department of Pathology, Harbin Medical University, Harbin, China
raw_author_name: Chun-Wei Chen
raw_affiliation_strings: Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA. chen.chun-wei@mayo.edu
Division of Epigenetic and Transcriptional Engineering, Beckman Research Institute, City of Hope, Duarte, CA, USA. chen.chun-wei@mayo.edu
Laboratory of Gene Editing and Cellular Engineering, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA. chen.chun-wei@mayo.edu
Division of Epigenetic and Transcriptional Engineering, Beckman Research Institute, City of Hope, Duarte, CA, USA
Laboratory of Gene Editing and Cellular Engineering, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, USA
raw_author_name: Rui Su
raw_affiliation_strings: Center for RNA Biology and Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA. rsu@coh.org
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA. rsu@coh.org
Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA, USA