Efficient production of ursodeoxycholic acid via a deep eutectic solvent-enabled 7α- and 7β-hydroxysteroid dehydrogenase cascade system with enhanced solubility of 7-keto-lithocholic acid
Year: 2025
Type: article
Language: en
Topic: Enzyme Catalysis and Immobilization
Authors and affiliations:
raw_author_name: Byoung Wook Jeon
raw_affiliation_strings: Department of Chemical Engineering, College of Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea. Electronic address: bwjeon@khu.ac.kr
Department of Chemical Engineering, College of Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. Electronic address: bwjeon@khu.ac.kr
raw_author_name: Ye Jean Jung
raw_affiliation_strings: Department of Biological and Chemical Engineering, Hongik University, Sejong-si, 30016, Republic of Korea. Electronic address: yejean22@gmail.com
raw_author_name: Mi Hee Ryu
raw_affiliation_strings: Green Carbon Research Center, Chemical & Process Technology Division, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea. Electronic address: miheeryu@krict.re.kr
raw_author_name: Siseon Lee
raw_affiliation_strings: Department of Biotechnology, The Catholic University of Korea, Bucheon, Gyeonggi-do, 14662, Republic of Korea. Electronic address: 2siseon85@gmail.com
raw_author_name: Jihyun Yoon
raw_affiliation_strings: Department of Chemical Engineering, College of Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea. Electronic address: jh60821@naver.com
raw_author_name: Eun-Gyeong Lee
raw_affiliation_strings: Ace biopharm Co., Ltd. Biotechnology Center, Bio-Venture Town, 1662 Yuseong-daero, Yuseong-gu, Daejeon, 34114, Republic of Korea. Electronic address: white2534@naver.com
raw_author_name: Jae-Bum Park
raw_affiliation_strings: Ace biopharm Co., Ltd. Biotechnology Center, Bio-Venture Town, 1662 Yuseong-daero, Yuseong-gu, Daejeon, 34114, Republic of Korea. Electronic address: unitsaer@gmail.com
raw_author_name: Hyung-wook Jang
raw_affiliation_strings: Ace biopharm Co., Ltd. Biotechnology Center, Bio-Venture Town, 1662 Yuseong-daero, Yuseong-gu, Daejeon, 34114, Republic of Korea. Electronic address: hwjang63@gmail.com
raw_author_name: Young-Soo Hong
raw_affiliation_strings: Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea. Electronic address: hongsoo@kribb.re.kr
raw_author_name: Jungoh Ahn
raw_affiliation_strings: Biotechnology Process Engineering Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, 28116, Republic of Korea. Electronic address: ahnjo@kribb.re.kr
raw_author_name: Bong Hyun Sung
raw_affiliation_strings: Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea; School of Biotechnology, Korea University of Science and Technology (UST), Daejeon, 34141, Republic of Korea; Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. Electronic address: bhsung@kribb.re.kr
Synthetic Biology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea; School of Biotechnology, Korea University of Science and Technology (UST), Daejeon, 34141, Republic of Korea; Bioenergy Research Laboratory, Department of Biotechnology, AKS University, Satna, Madhya Pradesh, 485001, India. Electronic address: bhsung@kribb.re.kr
raw_author_name: Ashutosh Pandey
raw_affiliation_strings: Department of Biotechnology & Bioengineering, School of Biosciences & Technology, Galgotias University, Greater Noida, 203201, India. Electronic address: ashuthoshdut@gmail.com
Research Center for Bio-based Chemicals, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea. Electronic address: ashuthoshkscem@gmail.com
raw_author_name: Bong Keun Song
raw_affiliation_strings: Research Center for Bio-based Chemicals, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea. Electronic address: bk2000s@naver.com
Department of Chemical and Biological Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. Electronic address: bk2000s@naver.com
raw_author_name: Kyungmoon Park
raw_affiliation_strings: Department of Biological and Chemical Engineering, Hongik University, Sejong-si, 30016, Republic of Korea. Electronic address: pkm2510@hongik.ac.kr
raw_author_name: Wangyun Won
raw_affiliation_strings: Department of Chemical and Biological Engineering, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. Electronic address: wwon@korea.ac.kr
Department of Chemical Engineering, College of Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea. Electronic address: wwon@korea.ac.kr
raw_author_name: Jeong Chan Joo
raw_affiliation_strings: Department of Chemical Engineering, College of Engineering, Kyung Hee University, Yongin-si, Gyeonggi-do, 17104, Republic of Korea. Electronic address: jcjoo@khu.ac.kr
Green Carbon Research Center, Chemical & Process Technology Division, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, Republic of Korea. Electronic address: jcjoo@khu.ac.kr