Design, Synthesis, and Biological Evaluation of Highly Potent Boronic Acid (Boronate Ester)-Bearing Heteroaryldihydropyrimidine Derivatives as HBV Capsid Assembly Modulators
Year: 2025
Type: article
Language: en
Topic: Hepatitis B Virus Studies
Authors and affiliations:
raw_author_name: Yu Jin
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, P. R. China
raw_author_name: Yang Sun
raw_affiliation_strings: Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College
Shandong University
Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College, Shandong University, Jinan 250012, Shandong, P. R. China
raw_author_name: Shujie Zhao
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, P. R. China
raw_author_name: Shuo Wang
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, P. R. China
raw_author_name: Yutong Dou
raw_affiliation_strings: Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College
Shandong University
Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College, Shandong University, Jinan 250012, Shandong, P. R. China
raw_author_name: Kai Wang
raw_affiliation_strings: Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College
Shandong University
Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College, Shandong University, Jinan 250012, Shandong, P. R. China
raw_author_name: Qilan Li
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100, S. Grand Boulevard, St. Louis, Missouri 63104, United States
raw_author_name: John E. Tavis
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100, S. Grand Boulevard, St. Louis, Missouri 63104, United States
raw_author_name: Zhuanchang Wu
raw_affiliation_strings: Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College
Shandong University
Key Laboratory for Experimental Teratology of Ministry of Education, Key Laboratory of Infection and Immunity of Shandong Province and Dept. Immunology, School of Basic Medical Sciences, Cheeloo Medical College, Shandong University, Jinan 250012, Shandong, P. R. China
raw_author_name: Peng Zhan
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, P. R. China
raw_author_name: Xinyong Liu
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, P. R. China