Macrophage PD-1 regulates energy expenditure and metabolic dysfunction under immune checkpoint blockade
Year: 2025
Type: article
Language: en
Topic: Autophagy in Disease and Therapy
Authors and affiliations:
raw_author_name: Ming-Ming Wu
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China
raw_author_name: Yan-Chao Yang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China
raw_author_name: Zhi-Qiang Hu
raw_affiliation_strings: Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Zhejiang, China
raw_author_name: Jie-Yu Chang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Han Xiao
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Chang Miao
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Bo-Wen Zhang
raw_affiliation_strings: Department of Pharmacy, Beidahuang Industry Group General Hospital, Harbin, China
Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Zhi-Xi He
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Di Zhu
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Yu-Ran Duan
raw_affiliation_strings: Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Zhejiang, China
raw_author_name: Shuo Wang
raw_affiliation_strings: Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, Jinan, China
raw_author_name: Jian-Yu Liu
raw_affiliation_strings: Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China
raw_author_name: Zhan-Peng Guo
raw_affiliation_strings: Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Zhejiang, China
raw_author_name: Yu Sun
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Dan-Yang Liu
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Miao Yu
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Yue Zhang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Jian-Jun Mao
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Shuai Jiang
raw_affiliation_strings: Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China
raw_author_name: Bing-Kun Zhang
raw_affiliation_strings: Department of Pharmacy, Beidahuang Industry Group General Hospital, Harbin, China
Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Zhu Mei
raw_affiliation_strings: State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China; Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China
raw_author_name: Jun Gao
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Chen Liang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Qiu-Shi Wang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China
raw_author_name: Chang-Jiang Yu
raw_affiliation_strings: Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China
raw_author_name: Dan Zhao
raw_affiliation_strings: Department of Clinical Pharmacy, The Second Affiliated Hospital, Harbin Medical University, Harbin, China
raw_author_name: Cheng-Hui Yan
raw_affiliation_strings: State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China; Cardiovascular Research Institute and Department of Cardiology, General Hospital of Northern Theater Command, Shenyang, China
raw_author_name: Yue Li
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China
raw_author_name: Zhen-Wei Pan
raw_affiliation_strings: State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China; Department of Pharmacology, State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education, Harbin Medical University, Harbin, China
raw_author_name: Zheng Chen
raw_affiliation_strings: HIT Center for Life Sciences, School of Life Science and Technology, Harbin Institute of Technology, Harbin, China
raw_author_name: Da-Qian Xu
raw_affiliation_strings: Zhejiang Provincial Key Laboratory of Pancreatic Disease, the First Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Zhejiang University, Zhejiang, China
raw_author_name: Tong Liu
raw_affiliation_strings: Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China. Electronic address: liutong@hrbmu.edu.cn
raw_author_name: Yong Ji
raw_affiliation_strings: State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China; Department of Pharmacology, State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education, Harbin Medical University, Harbin, China; Medical Basic Research Innovation Center for Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, Key Laboratory of Drug Targets and Translational Medicine for Cardio-Cerebrovascular Diseases, Nanjing Medical University, Nanjing, China. Electronic address: yongji@njmu.edu.cn
raw_author_name: Zhi-Ren Zhang
raw_affiliation_strings: Departments of Cardiology, Critical Care Medicine and Colorectal Surgery, The First Affiliated Hospital of Harbin Medical University, NHC Key Laboratory of Cell Transplantation, Key Laboratory of Myocardial Ischemia, Chinese Ministry of Education, Harbin, China; Departments of Oncological Surgery, Cardiology, and Clinical Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Heilongjiang Key Laboratory for Metabolic Disorder and Cancer Related Cardiovascular Diseases, Harbin, China; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Harbin Medical University, Harbin, China. Electronic address: zhirenz@163.com