Structural-guided identification of two modulators of β−1,3-glucan synthase FKS1
Year: 2025
Type: article
Language: en
Topic: Signaling Pathways in Disease
Authors and affiliations:
raw_author_name: Jialu Li
raw_affiliation_strings: Children's Medicine Key Laboratory of Sichuan Province, Chengdu, China
Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education), School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, China
raw_author_name: Jian Li
raw_affiliation_strings: Children's Medicine Key Laboratory of Sichuan Province, Chengdu, China
Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education), School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, China
raw_author_name: Angqi Zhu
raw_affiliation_strings: State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
raw_author_name: Xinli Dai
raw_affiliation_strings: Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
raw_author_name: Juxiu Liu
raw_affiliation_strings: Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
raw_author_name: Huayi Liu
raw_affiliation_strings: State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education), School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, China
raw_author_name: Zhili Xia
raw_affiliation_strings: The First Clinical Medical College, Lanzhou University, Lanzhou, China
raw_author_name: Yuefan Dong
raw_affiliation_strings: Key Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, Changchun, Jilin, China
raw_author_name: Wenyu Qian
raw_affiliation_strings: Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
raw_author_name: Lunzhi Dai
raw_affiliation_strings: State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics and General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China
raw_author_name: Li Guo
raw_affiliation_strings: Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China
NHC Key Laboratory of Chronobiology, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Sichuan University, Chengdu, China
raw_author_name: Chuangye Yan
raw_affiliation_strings: State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. yancy2019@tsinghua.edu.cn
raw_author_name: Dong Deng
raw_affiliation_strings: Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China. dengd@scu.edu.cn
NHC Key Laboratory of Chronobiology, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Sichuan University, Chengdu, China. dengd@scu.edu.cn
raw_author_name: Yunzi Luo
raw_affiliation_strings: State Key Laboratory of Synthetic Biology, Frontiers Science Center for Synthetic Biology (Ministry of Education), School of Synthetic Biology and Biomanufacturing, Tianjin University, Tianjin, China. yunzi.luo@tju.edu.cn
raw_author_name: Xiang Wang
raw_affiliation_strings: Children's Medicine Key Laboratory of Sichuan Province, Chengdu, China. xiangwang@scu.edu.cn
Department of Andrology/Sichuan Human Sperm Bank, West China Second University Hospital, Sichuan University, Chengdu, Sichuan Province, China. xiangwang@scu.edu.cn
Department of Obstetrics, Key Laboratory of Birth Defects and Related Disease of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, China. xiangwang@scu.edu.cn
NHC Key Laboratory of Chronobiology, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Sichuan University, Chengdu, China. xiangwang@scu.edu.cn