PITX2 dosage-dependent changes in pacemaker cell state underlie sinus node dysfunction and atrial arrhythmias
Year: 2025
Type: article
Language: en
Topic: Congenital heart defects research
Authors and affiliations:
raw_author_name: Lieve E. van der Maarel
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: M. Ridwane Mungroo
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Otto J. Mulleners
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Mathilde R. Rivaud
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
Laboratory of Experimental Cardiology, Leiden University Medical Center, Leiden, the Netherlands
raw_author_name: Arie O. Verkerk
raw_affiliation_strings: Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Karel van Duijvenboden
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Freek H. T. Tiel Groenestege
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Jeffrey D. Steimle
raw_affiliation_strings: Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA
raw_author_name: Lianne Fokkert
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Corrie de Gier-de Vries
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Mischa Klerk
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Arie. R. Boender
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: James F. Martin
raw_affiliation_strings: Department of Integrative Physiology, Baylor College of Medicine, Houston, TX, USA
raw_author_name: Bjarke Jensen
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Gerard J. J. Boink
raw_affiliation_strings: Department of Clinical Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
PacingCure BV, Amsterdam, the Netherlands
raw_author_name: Harsha D. Devalla
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands
raw_author_name: Vincent M. Christoffels
raw_affiliation_strings: Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands. v.m.christoffels@amsterdamumc.nl
Department of Medical Biology, Amsterdam Cardiovascular Sciences, Amsterdam Reproduction and Development, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, the Netherlands