Surface expression of antitoxin on engineered bacteria neutralizes genotoxic colibactin in the gut
Year: 2025
Type: article
Language: en
Topic: Cancer Research and Treatments
Authors and affiliations:
raw_author_name: Shaobo Yang
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
raw_author_name: Zongqi Wang
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Chengyuan Fang
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA
Department of Esophageal and Mediastinum, Harbin Medical University Cancer Hospital, Harbin, China
raw_author_name: Mengdi Yang
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
raw_author_name: Saleh Khawaled
raw_affiliation_strings: Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
raw_author_name: Shanna Bonanno
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
raw_author_name: Neel S. Joshi
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Yun Wei
raw_affiliation_strings: Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Ke Zhang
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Valeria Márquez-Pellegrin
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
raw_author_name: Ming Guan
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
raw_author_name: Songqi Zhang
raw_affiliation_strings: Department of Bioengineering, Northeastern University, Boston, MA, USA
raw_author_name: Anna Clara Bader
raw_affiliation_strings: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
raw_author_name: Ningyuan Ye
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Amber E. Haley
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA
raw_author_name: Michael K. Dame
raw_affiliation_strings: Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Jason R. Spence
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA
Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA
Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Xuesong He
raw_affiliation_strings: Department of Microbiology, ADA Forsyth Institute, Somerville, MA, USA
raw_author_name: James G. Fox
raw_affiliation_strings: Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
raw_author_name: Ömer H. Yilmaz
raw_affiliation_strings: Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA
Department of Pathology, Beth Israel Deaconness Medical Center, Harvard Medical School, Boston, MA, USA
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
raw_author_name: Yatrik M. Shah
raw_affiliation_strings: Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, MI, USA
University of Michigan Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Rizwan Romee
raw_affiliation_strings: Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
raw_author_name: Jiahe Li
raw_affiliation_strings: Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA. jiaheli@umich.edu
Department of Biomedical Engineering, College of Engineering and School of Medicine, University of Michigan, Ann Arbor, MI, USA