Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer
Year: 2025
Type: article
Language: en
Topic: Immune Cell Function and Interaction
Authors and affiliations:
raw_author_name: Max Heiduk
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Carolin Beer
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
raw_author_name: Sarah Cronjaeger
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Emily A. Kawaler
raw_affiliation_strings: Perlmutter Cancer Center, NYU Langone Health, New York, New York, USA
Perlmutter Cancer Center, NYU Langone Health, New York, United States of America
raw_author_name: Ulrich Sommer
raw_affiliation_strings: Institute of Pathology, Faculty of Medicine Carl Gustav Carus, and
National Center for Tumor Diseases (NCT), Biobank Dresden, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Institute of Pathology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
raw_author_name: Franziska Baenke
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: David Digomann
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Loreen Natusch Bufe
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Charlotte Reiche
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Jessica Glück
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
raw_author_name: Franziska Hoffmann
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
raw_author_name: Sungsik Kim
raw_affiliation_strings: Department of Surgery, Moores Cancer Center, UC San Diego Health, San Diego, California, USA
Department of Surgery, Moores Cancer Center, UC San Diego Health, San Diego, United States of America
raw_author_name: Daniel E. Stange
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Diane M. Simeone
raw_affiliation_strings: Department of Surgery, Moores Cancer Center, UC San Diego Health, San Diego, California, USA
Department of Surgery, Moores Cancer Center, UC San Diego Health, San Diego, United States of America
raw_author_name: Jürgen Weitz
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Lena Seifert
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Else Kröner Clinician Scientist Professor for Translational Tumor Immunological Research, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany
raw_author_name: Adrian M. Seifert
raw_affiliation_strings: Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
German Cancer Consortium (DKTK), Partner Site Dresden, German Cancer Research Center (DKFZ), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany
National Center for Tumor Diseases (NCT), Dresden, Germany