B cell depletion and BAFF receptor blockade with ianalumab (VAY736) for the treatment of moderate-to-severe systemic lupus erythematosus: a phase 2 randomised, double-blind, placebo-controlled trial with subsequent open-label treatment
Year: 2025
Type: article
Language: en
Topic: Systemic Lupus Erythematosus Research
Authors and affiliations:
raw_author_name: Nancy Agmon-Levin
raw_affiliation_strings: Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Aviv Univ, Tel Aviv, Israel
raw_author_name: Stanislav Ignatenko
raw_affiliation_strings: Charité Research Organisation GmbH, Berlin, Germany
raw_author_name: Alexander Gordienko
raw_affiliation_strings: Department of Hospital Therapy, SM Kirov Military Medical Academy, St Petersburg, Russia
raw_author_name: Josefina Cortés-Hernández
raw_affiliation_strings: Lupus Unit, Rheumatology Department, Vall d'Hebron Hospitals, Barcelona, Spain
raw_author_name: Pongthorn Narongroeknawin
raw_affiliation_strings: Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand
raw_author_name: Katarzyna Romanowska-Próchnicka
raw_affiliation_strings: Department of Biophysics, Physiology and Pathophysiology, Medical University of Warsaw, Warsaw, Poland
raw_author_name: Nan Shen
raw_affiliation_strings: Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jaiotong University School of Medicine, Shanghai, China
raw_author_name: Hana Ciferská
raw_affiliation_strings: Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic
raw_author_name: Masanari Kodera
raw_affiliation_strings: Department of Dermatology, Japan Community Healthcare Organization, Chukyo Hospital, Nagoya, Japan
raw_author_name: Wei J Cheng-Chung
raw_affiliation_strings: Department of Allergy, Immunology & Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan; Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan
raw_author_name: Piotr Leszczynski
raw_affiliation_strings: Department of Internal Medicine and Metabolic Disorders, Poznan University of Medical Sciences, Poznan, Poland
raw_author_name: Joung-Liang Lan
raw_affiliation_strings: Rheumatology and Immunology Center, China Medical University Hospital, Taichung, Taiwan
raw_author_name: Eduardo Mysler
raw_affiliation_strings: Organizacion Medica de Investigacion, Buenos Aires, Argentina
raw_author_name: Rafal Wojciechowski
raw_affiliation_strings: Department of Rheumatology and Systemic Connective Tissue Diseases, University Hospital No. 2, Bydgoszcz, Poland
raw_author_name: Tunde Tarr
raw_affiliation_strings: Division of Clinical Immunology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
raw_author_name: Elena Vishneva
raw_affiliation_strings: LLC Family Clinic, Yekaterinburg, Russia
raw_author_name: Yi-Hsing Chen
raw_affiliation_strings: Division of Allergy, Immunology and Rheumatology, Taichung Veterans General Hospital, Taichung, Taiwan
raw_author_name: Yuko Kaneko
raw_affiliation_strings: Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan
raw_author_name: Stephanie Finzel
raw_affiliation_strings: Department of Rheumatology and Clinical Immunology, University Medical Centre Freiburg, Freiburg, Germany
raw_author_name: Alberta Hoi
raw_affiliation_strings: Department of Rheumatology, Monash Health, Monash University, Melbourne, VIC, Australia
raw_author_name: Masato Okada
raw_affiliation_strings: Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan
raw_author_name: Ajchara Koolvisoot
raw_affiliation_strings: Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
raw_author_name: Shin-Seok Lee
raw_affiliation_strings: Division of Rheumatology, Department of Internal Medicine, Chonnam National University Medical School and Hospital, Gwangju, South Korea
raw_author_name: Dai Lie
raw_affiliation_strings: Department of Rheumatology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
raw_author_name: Hiroshi Kaneko
raw_affiliation_strings: Division of Rheumatic Disease, National Centre for Global Health and Medicine, Tokyo, Japan
raw_author_name: Bernadette Rojkovich
raw_affiliation_strings: Department of Rheumatology and Physiotherapy, Polyclinic of the Hospitaller Brothers of St. John of God, Semmelweis University, Budapest, Hungary
raw_author_name: Lingyun Sun
raw_affiliation_strings: Department of Rheumatology and Immunology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China
raw_author_name: Eugeny Zotkin
raw_affiliation_strings: VA Nasonova Research Institute of Rheumatology, Moscow, Russia
raw_author_name: Jean-Francoise Viallard
raw_affiliation_strings: Department of Internal Medicine, CHU de Bordeaux, Hôpital Haut-Lévêque, Pessac, France
raw_author_name: Berta Paula Magallares López
raw_affiliation_strings: Department of Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
raw_author_name: Swati Aashish Ghanshani
raw_affiliation_strings: Novartis Healthcare Pvt. Ltd, Hyderabad, India
raw_author_name: Carol Lau
raw_affiliation_strings: Novartis Pharmaceuticals Corp, East Hanover, NJ, USA
raw_author_name: Alexandre Avrameas
raw_affiliation_strings: Novartis Pharma AG, Basel, Switzerland
raw_author_name: Carole Sips
raw_affiliation_strings: Novartis Pharma AG, Basel, Switzerland
raw_author_name: Stephen John Oliver
raw_affiliation_strings: Novartis Pharma AG, Basel, Switzerland. Electronic address: stephen.oliver@novartis.com