First-in-child phase I trial of p-STAT3 inhibitor WP1066 in pediatric brain tumor patients
Year: 2025
Type: article
Language: en
Topic: Cytokine Signaling Pathways and Interactions
Authors and affiliations:
raw_author_name: Robert C. Castellino
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Hope Mumme
raw_affiliation_strings: Department of Biomedical Informatics, Emory University, Atlanta, Georgia, USA
Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, United States of America
raw_author_name: Andrea Franson
raw_affiliation_strings: Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA
Department of Pediatrics, University of Michigan Medical School, Ann Arbor, United States of America
raw_author_name: Bing Yu
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Hope Robinson
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Kavita Dhodapkar
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Dolly Aguilera
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Matthew Schniederjan
raw_affiliation_strings: Department of Pathology, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, United States of America
raw_author_name: Rohali Keesari
raw_affiliation_strings: Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, United States of America
raw_author_name: Zhulin He
raw_affiliation_strings: Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, United States of America
raw_author_name: Manoj Bhasin
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Biomedical Informatics, Emory University, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America
raw_author_name: Waldemar Priebe
raw_affiliation_strings: Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, United States of America
raw_author_name: Amy B. Heimberger
raw_affiliation_strings: Department of Neurological Surgery, Malnati Brain Tumor Institute of the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Department of Neurological Surgery, Malnati Brain Tumor Institute of the Ro, Feinberg School of Medicine, Northwestern University, Chicago, United States of America
raw_author_name: Tobey J. MacDonald
raw_affiliation_strings: Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, Georgia, USA
Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA
Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, United States of America