Limitations in PPARα-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells
Year: 2025
Type: article
Language: en
Topic: Pancreatic function and diabetes
Authors and affiliations:
raw_author_name: Anne C. Lietzke
raw_affiliation_strings: Department of Pharmacology Graduate Program, University of Michigan Medical School, Ann Arbor, MI, USA
Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Emily M. Walker
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Elizabeth Bealer
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Kelly Crumley
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Jessica King
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Ava M. Stendahl
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Jie Zhu
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Gemma L. Pearson
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Elena Levi-D’Ancona
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Belle Henry-Kanarek
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Immunology Graduate Program, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Rebecca K. Davidson
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Jin Li
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Emma C. Reck
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Yifei Wu
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Manikanta Arnipalli
raw_affiliation_strings: Division of Nephrology and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: John-Paul Pham
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Lakshmi Mundada
raw_affiliation_strings: Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA
Division of Cardiology and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Frankel Cardiovascular Regeneration Core Laboratory University of Michigan, Ann Arbor, MI, USA
raw_author_name: Vaibhav Sidarala
raw_affiliation_strings: Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
raw_author_name: Todd J. Herron
raw_affiliation_strings: Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA
Division of Cardiology and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Frankel Cardiovascular Regeneration Core Laboratory University of Michigan, Ann Arbor, MI, USA
raw_author_name: Maria M. Coronel
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Subramaniam Pennathur
raw_affiliation_strings: Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA
Division of Nephrology and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
raw_author_name: Jesper G. S. Madsen
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
raw_author_name: Lonnie D. Shea
raw_affiliation_strings: Department of Biomedical Engineering, University of Michigan School of Engineering, Ann Arbor, MI, USA
raw_author_name: Scott A. Soleimanpour
raw_affiliation_strings: Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA. ssol@med.umich.edu
Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA. ssol@med.umich.edu
VA Ann Arbor Healthcare System, Ann Arbor, MI, USA. ssol@med.umich.edu
Division of Metabolism, Endocrinology and Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
VA Ann Arbor Healthcare System, Ann Arbor, MI, USA