C/EBPβ-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma
Year: 2025
Type: article
Language: en
Topic: Signaling Pathways in Disease
Authors and affiliations:
raw_author_name: Zujian Xiong
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Qinglin Kong
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Bhuvitha Chagantipati
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Amelia Stepniak
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Ambika P. Jaswal
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
Department of Radiology, Weill Cornell Medical College, New York, NY, USA
raw_author_name: Chaim T. Sneiderman
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Yuanyuan Han
raw_affiliation_strings: Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Sydney A. Jackson
raw_affiliation_strings: Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Rebecca A. Raphael
raw_affiliation_strings: Institute for Drug Research (IDR), School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Wei Zhang
raw_affiliation_strings: Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Muzi Li
raw_affiliation_strings: The Second School of Clinical Medicine, Anhui Medical University, Hefei, Anhui, China
raw_author_name: Yapeng Chao
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Bin Qin
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
National Center for International Research in Cell and Gene Therapy, Sino-British Research Center for Molecular Oncology, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, Henan, China
raw_author_name: Zeynep Dulkadir
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA
raw_author_name: Lance Schwegman
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA
raw_author_name: Yihao Zhang
raw_affiliation_strings: Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
raw_author_name: Chloe Kuminkoski
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Megan A. Mahlke
raw_affiliation_strings: Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Poulomi Nath
raw_affiliation_strings: Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Baoli Hu
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Pascal O. Zinn
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Megan Mantica
raw_affiliation_strings: Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Sameer Agnihotri
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Yael Nechemia-Arbely
raw_affiliation_strings: Department of Pharmacology & Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Ian F. Pollack
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Lora H. Rigatti
raw_affiliation_strings: Division of Laboratory Animal Resources, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
UPMC Hillman Cancer Center, Pittsburgh, PA, USA
raw_author_name: Thomas G. Forsthuber
raw_affiliation_strings: Department of Molecular Microbiology and Immunology, University of Texas at San Antonio, San Antonio, TX, USA
raw_author_name: Xuejun Li
raw_affiliation_strings: Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, Hunan, China
Hunan International Scientific and Technological Cooperation Base of Brain Tumor Research, Xiangya Hospital, Central South University, Changsha, China
raw_author_name: Itay Raphael
raw_affiliation_strings: Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. Itay.Raphael@mail.huji.ac.il
Institute for Drug Research (IDR), School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Itay.Raphael@mail.huji.ac.il
raw_author_name: Gary Kohanbash
raw_affiliation_strings: Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu
Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA. gary.kohanbash2@chp.edu