Intact Proteoform Analysis by Capillary Electrophoresis–Mass Spectrometry. Are We There Yet?
Year: 2025
Type: article
Language: en
Topic: Advanced Proteomics Techniques and Applications
Authors and affiliations:
raw_author_name: Noah Gould
raw_affiliation_strings: Barnett Institute of Chemical and Biological Analysis and Department of Chemistry &amp; Chemical Biology Northeastern University  Boston MA USA
Both authors contributed equally to this work
Barnett Institute of Chemical and Biological Analysis and Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Qianjie Wang
raw_affiliation_strings: Department of Chemistry Michigan State University  East Lansing MI USA
Department of Chemistry, Michigan State University, East Lansing, MI, USA
Both authors contributed equally to this work
raw_author_name: Jeffrey N. Agar
raw_affiliation_strings: Barnett Institute of Chemical and Biological Analysis and Department of Chemistry &amp; Chemical Biology Northeastern University  Boston MA USA
Barnett Institute of Chemical and Biological Analysis and Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Jennifer S. Brodbelt
raw_affiliation_strings: Department of Chemistry University of Texas  Austin TX USA
Department of Chemistry, University of Texas, Austin, TX, USA
raw_author_name: Daoyang Chen
raw_affiliation_strings: Discovery Biologics Merck Research Laboratory  USA
Discovery Biologics, Merck Research Laboratory, USA
raw_author_name: Kellye A. Cupp‐Sutton
raw_affiliation_strings: Department of Chemistry and Biochemistry University of Alabama  Tuscaloosa AL USA
Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL, USA
raw_author_name: Elena Domínguez‐Vega
raw_affiliation_strings: Center for Proteomics and Metabolomics Leiden University Medical Center  Leiden The Netherlands
Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
raw_author_name: Fei Fang
raw_affiliation_strings: Department of Chemistry Michigan State University  East Lansing MI USA
Department of Chemistry, Michigan State University, East Lansing, MI, USA
raw_author_name: Marianne Fillet
raw_affiliation_strings: Laboratory for the Analysis of Medicines Center for Interdisciplinary Research on Medicines (CIRM) University of Liege Quartier Hospital  Liege Belgium
Laboratory for the Analysis of Medicines, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege, Quartier Hospital, Liege, Belgium
raw_author_name: Matthew S Fischer
raw_affiliation_strings: Department of Chemistry University of Wisconsin‐Madison  Madison Wisconsin 53706 USA
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706 USA
raw_author_name: Attila Gaspar
raw_affiliation_strings: Department of Inorganic and Analytical Chemistry University of Debrecen  Debrecen Hungary
Department of Inorganic and Analytical Chemistry, University of Debrecen, Debrecen, Hungary
raw_author_name: Ying Ge
raw_affiliation_strings: Department of Cell and Regenerative Biology and Human Proteomics Program University of Wisconsin‐Madison  Madison Wisconsin 53705 USA
Department of Chemistry University of Wisconsin‐Madison  Madison Wisconsin 53706 USA
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706 USA
raw_author_name: Marie‐Jia Gou
raw_affiliation_strings: Laboratory for the Analysis of Medicines Center for Interdisciplinary Research on Medicines (CIRM) University of Liege Quartier Hospital  Liege Belgium
Laboratory for the Analysis of Medicines, Center for Interdisciplinary Research on Medicines (CIRM), University of Liege, Quartier Hospital, Liege, Belgium
raw_author_name: Michal Greguš
raw_affiliation_strings: Barnett Institute of Chemical and Biological Analysis and Department of Chemistry &amp; Chemical Biology Northeastern University  Boston MA USA
Barnett Institute of Chemical and Biological Analysis and Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Christoph Gstöttner
raw_affiliation_strings: Center for Proteomics and Metabolomics Leiden University Medical Center  Leiden The Netherlands
Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, The Netherlands
raw_author_name: Narmin Hamidli
raw_affiliation_strings: Department of Inorganic and Analytical Chemistry University of Debrecen  Debrecen Hungary
Department of Inorganic and Analytical Chemistry, University of Debrecen, Debrecen, Hungary
raw_author_name: Amanda Helms
raw_affiliation_strings: Department of Chemistry University of Texas  Austin TX USA
Department of Chemistry, University of Texas, Austin, TX, USA
raw_author_name: Md Amin Hossain
raw_affiliation_strings: Barnett Institute of Chemical and Biological Analysis and Department of Chemistry &amp; Chemical Biology Northeastern University  Boston MA USA
Department of Neurosurgery Brigham and Women's Hospital Harvard Medical School  Boston MA USA
Barnett Institute of Chemical and Biological Analysis and Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA
Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
raw_author_name: Kyle J. Juetten
raw_affiliation_strings: Department of Chemistry University of Texas  Austin TX USA
Department of Chemistry, University of Texas, Austin, TX, USA
raw_author_name: Neil L. Kelleher
raw_affiliation_strings: Departments of Chemistry and Molecular Biosciences the Chemistry of Life Processes Institute and the Proteomics Center of Excellence Northwestern University  Evanston IL USA
Departments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA
raw_author_name: Tobias Kraus
raw_affiliation_strings: Department of Chemistry Aalen University  Aalen Germany
Department of Chemistry, Aalen University, Aalen, Germany
raw_author_name: Eli J. Larson
raw_affiliation_strings: Department of Chemistry University of Wisconsin‐Madison  Madison Wisconsin 53706 USA
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, 53706 USA
raw_author_name: J. Scott Mellors
raw_affiliation_strings: 908 Devices Inc.  Boston MA USA
908 Devices Inc., Boston, MA, USA
raw_author_name: Cynthia Nagy
raw_affiliation_strings: Department of Inorganic and Analytical Chemistry University of Debrecen  Debrecen Hungary
Department of Inorganic and Analytical Chemistry, University of Debrecen, Debrecen, Hungary
raw_author_name: Christian Neusüß
raw_affiliation_strings: Department of Chemistry Aalen University  Aalen Germany
Department of Chemistry, Aalen University, Aalen, Germany
raw_author_name: Erin A. Redman
raw_affiliation_strings: 908 Devices Inc.  Boston MA USA
908 Devices Inc., Boston, MA, USA
raw_author_name: Jasmin Schairer
raw_affiliation_strings: Department of Chemistry Aalen University  Aalen Germany
Department of Chemistry, Aalen University, Aalen, Germany
raw_author_name: Si Wu
raw_affiliation_strings: Department of Chemistry and Biochemistry University of Alabama  Tuscaloosa AL USA
Department of Chemistry and Biochemistry University of Oklahoma  Norman OK USA
Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL, USA
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA
raw_author_name: Tian Xu
raw_affiliation_strings: Departments of Chemistry and Molecular Biosciences the Chemistry of Life Processes Institute and the Proteomics Center of Excellence Northwestern University  Evanston IL USA
Departments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, USA
raw_author_name: Zhitao Zhao
raw_affiliation_strings: Department of Chemistry and Biochemistry University of Alabama  Tuscaloosa AL USA
Department of Chemistry and Biochemistry University of Oklahoma  Norman OK USA
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK, USA
Department of Chemistry and Biochemistry, University of Alabama, Tuscaloosa, AL, USA
raw_author_name: Guijie Zhu
raw_affiliation_strings: Department of Chemistry Michigan State University  East Lansing MI USA
Department of Chemistry, Michigan State University, East Lansing, MI, USA
raw_author_name: Alexander R. Ivanov
raw_affiliation_strings: Barnett Institute of Chemical and Biological Analysis and Department of Chemistry &amp; Chemical Biology Northeastern University  Boston MA USA
Barnett Institute of Chemical and Biological Analysis and Department of Chemistry & Chemical Biology, Northeastern University, Boston, MA, USA
raw_author_name: Kevin Jooß
raw_affiliation_strings: Division of Bioanalytical Chemistry Department of Chemistry and Pharmaceutical Sciences Amsterdam Institute of Molecular and Life Sciences Vrije Universiteit Amsterdam Centre for Analytical Sciences Amsterdam (CASA)  Amsterdam The Netherlands
Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, Centre for Analytical Sciences Amsterdam (CASA), Amsterdam, The Netherlands
raw_author_name: Liangliang Sun
raw_affiliation_strings: Department of Chemistry Michigan State University  East Lansing MI USA
Department of Chemistry, Michigan State University, East Lansing, MI, USA