PPP2R2A insufficiency enhances PD-L1 immune checkpoint blockade efficacy in lung cancer through cGAS-STING activation
Year: 2025
Type: article
Language: en
Topic: interferon and immune responses
Authors and affiliations:
raw_author_name: Zhaojun Qiu
raw_affiliation_strings: The Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, Ohio, USA
Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, United States of America
raw_author_name: No-Joon Song
raw_affiliation_strings: College of Medicine, and
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio, USA
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncol, The Ohio State University, Columbus, United States of America
raw_author_name: Anqi Li
raw_affiliation_strings: College of Medicine, and
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio, USA
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncol, The Ohio State University, Columbus, United States of America
raw_author_name: Deepika Singh
raw_affiliation_strings: The Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, Ohio, USA
Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, United States of America
raw_author_name: Chandra B. Prasad
raw_affiliation_strings: The Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, Ohio, USA
Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, United States of America
raw_author_name: Chunhong Yan
raw_affiliation_strings: Georgia Cancer Center, Augusta University Medical College, Augusta, Georgia, USA
Georgia Cancer Center, Augusta University, Augusta, United States of America
raw_author_name: David P. Carbone
raw_affiliation_strings: James Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
The James Comprehensive Cancer Center, The Ohio State University, Columbus, United States of America
raw_author_name: Qi-en Wang
raw_affiliation_strings: The Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, Ohio, USA
Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, United States of America
raw_author_name: Xiaoli Zhang
raw_affiliation_strings: USF Health, University of South Florida, Tampa, Florida, USA
USF Health, University of South Florida, Tampa, United States of America
raw_author_name: Zihai Li
raw_affiliation_strings: College of Medicine, and
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio, USA
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncol, The Ohio State University, Columbus, United States of America
raw_author_name: Junran Zhang
raw_affiliation_strings: The Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, Ohio, USA
The James Comprehensive Cancer Center, Center for Metabolism, Columbus, Ohio, USA
The James Comprehensive Cancer Center, Pelotonia Institute for Immuno-Oncology, The Ohio State University, Columbus, Ohio, USA
Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine, Columbus, United States of America