Abrogation of aberrant glycolytic interactions eliminates senescent cells and alleviates aging-related dysfunctions
Year: 2025
Type: article
Language: en
Topic: Telomeres, Telomerase, and Senescence
Authors and affiliations:
raw_author_name: Takumi Mikawa
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Masahiro Kameda
raw_affiliation_strings: Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Sumiko Ikari
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Eri Shibata
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Shuyu Liu
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Sawa Miyagawa
raw_affiliation_strings: Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Koh Ono
raw_affiliation_strings: Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Tomiko Ito
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Akihiko Yoshizawa
raw_affiliation_strings: Department of Diagnostic Pathology, Nara Medical University, Nara, Japan
raw_author_name: Masataka Sugimoto
raw_affiliation_strings: Department of Cellular Pathology, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
raw_author_name: Shuichi Shibuya
raw_affiliation_strings: Aging Stress Response Research Project Team, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
Department of Regenerative Medicine, Faculty of Pharmacy, Sanyo-Onoda City University, Yamaguchi, Japan
raw_author_name: Takahiko Shimizu
raw_affiliation_strings: Aging Stress Response Research Project Team, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
Department of Food and Reproductive Function Advanced Research, Juntendo University Graduate School of Medicine, Tokyo, Japan
raw_author_name: Julio Almunia
raw_affiliation_strings: Department of Laboratory of Experimental Animals, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
raw_author_name: Noboru Ogiso
raw_affiliation_strings: Department of Laboratory of Experimental Animals, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
Faculty of Health and Medical Sciences, Aichi Shukutoku University, Obu, Aichi, Japan
raw_author_name: Gwladys Revêchon
raw_affiliation_strings: Team Labellisée la Ligue Contre le Cancer, Cancer Research Center of Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Lyon University, Lyon, France
raw_author_name: Alberta Palazzo
raw_affiliation_strings: Team Labellisée la Ligue Contre le Cancer, Cancer Research Center of Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Lyon University, Lyon, France
raw_author_name: David Bernard
raw_affiliation_strings: Team Labellisée la Ligue Contre le Cancer, Cancer Research Center of Lyon, Inserm U1052, CNRS UMR 5286, Centre Léon Bérard, Lyon University, Lyon, France
raw_author_name: Hiroaki Kanda
raw_affiliation_strings: Department of Pathology, Saitama Cancer Center, Saitama, Japan
raw_author_name: Tomoyoshi Soga
raw_affiliation_strings: Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan
raw_author_name: Keiyo Takubo
raw_affiliation_strings: Department of Cell Fate Biology and Stem Cell Medicine, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
Department of Stem Cell Biology, National Institute of Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan
raw_author_name: Shin Morioka
raw_affiliation_strings: Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan
raw_author_name: Junko Sasaki
raw_affiliation_strings: Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan
raw_author_name: Takehiko Sasaki
raw_affiliation_strings: Department of Biochemical Pathophysiology, Medical Research Laboratory, Institute of Integrated Research, Institute of Science Tokyo, Tokyo, Japan
raw_author_name: Akihiro Itamoto
raw_affiliation_strings: Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Takayuki Fujii
raw_affiliation_strings: Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan
Department of Orthopedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Hiroshi Seno
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Nobuya Inagaki
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan
raw_author_name: Hiroshi Kondoh
raw_affiliation_strings: Department of Diabetes, Endocrinology and Nutrition, Graduate School of Medicine, Kyoto University, Kyoto, Japan. hkondoh@kuhp.kyoto-u.ac.jp
Geriatric Unit, Graduate School of Medicine, Kyoto University, Kyoto, Japan. hkondoh@kuhp.kyoto-u.ac.jp