JMJD2 regulates enhancer–promoter interactions via biomolecular condensate formation
Year: 2025
Type: article
Language: en
Topic: Genomics and Chromatin Dynamics
Authors and affiliations:
raw_author_name: Shaoshuai Jiang
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Gynecology and Obstetrics, West China Second Hospital
raw_author_name: Xinyi Liu
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China
Department of Gynecology and Obstetrics, West China Second Hospital
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
raw_author_name: Zhuheng Zhang
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Gynecology and Obstetrics, West China Second Hospital
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
raw_author_name: Mingzhu Yang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
raw_author_name: Xing Zhu
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Lin Ma
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Longying Zhao
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Xiaoru Ling
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Ziqiang Zhou
raw_affiliation_strings: Department of Chemistry, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing, China
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Ziqiang Wu
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jiale Qu
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Haochen Li
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jiawei Liang
raw_affiliation_strings: Department of Chemistry, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing, China
raw_author_name: Zhiheng Deng
raw_affiliation_strings: Department of Chemistry, Tsinghua-Peking Joint Center for Life Sciences, MOE Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology, Tsinghua University, Beijing, China
raw_author_name: Qi Tian
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Xiaona Huang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Xianglin Huang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jin Tan
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jun Sun
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Department of Gynecology and Obstetrics, West China Second Hospital
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
raw_author_name: Jia Wang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
GMU-GIBH Joint School of Life Sciences, Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, China
raw_author_name: Diana Guallar
raw_affiliation_strings: Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela (USC)-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain
raw_author_name: Partha Pratim Das
raw_affiliation_strings: Department of Anatomy and Developmental Biology, Monash University, Wellington Road, Clayton, Victoria, Australia
raw_author_name: Luca Pinello
raw_affiliation_strings: Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston, MA, USA; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Molecular Pathology Unit, Center for Cancer Research, Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston, MA, USA
raw_author_name: Liang Wang
raw_affiliation_strings: Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei Key Laboratory of Genetic Regulation and Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan, China
raw_author_name: Hongfu Wu
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
raw_author_name: Dong-feng Huang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jichang Wang
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
GMU-GIBH Joint School of Life Sciences, Guangdong-Hong Kong-Macau Joint Laboratory for Cell Fate Regulation and Diseases, Guangzhou Medical University, Guangzhou, China
raw_author_name: Hancheng Lin
raw_affiliation_strings: Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
raw_author_name: Jin Bai
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China. bj@xzhmu.edu.cn
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
raw_author_name: Lili Fan
raw_affiliation_strings: Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Jinan University, Guangzhou, China. fanlili@jnu.edu.cn
Guangzhou Key Laboratory of Formula-Pattern of Traditional Chinese Medicine, School of Traditional Chinese Medicine, Jinan University, Guangzhou, China
raw_author_name: Wei Chi
raw_affiliation_strings: Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China. chiwei@mail.sysu.edu.cn
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China
raw_author_name: Xue Xiao
raw_affiliation_strings: Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China. xiaoxuela@scu.edu.cn
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Department of Gynecology and Obstetrics, West China Second Hospital
raw_author_name: Junjun Ding
raw_affiliation_strings: Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China; School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China. dingjunj@mail.sysu.edu.cn
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China. dingjunj@mail.sysu.edu.cn
Frontiers Medical Center, Tianfu Jincheng Laboratory; Department of Gynecology and Obstetrics, West China Second Hospital; West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China. dingjunj@mail.sysu.edu.cn
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China. dingjunj@mail.sysu.edu.cn
School of Basic Medical Sciences, Guangdong Medical University, Guangdong, China
Department of Gynecology and Obstetrics, West China Second Hospital
Cancer Institute, Cellular Therapeutics School of Medicine, Xuzhou Medical University, Jiangsu, China
Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Zhongshan School of Medicine, Sun Yat-Sen University, Guangdong, China
West China Biomedical Big Data Center, West China Hospital/West China School of Medicine, Sichuan University, Chengdu, China
Shenzhen Eye Hospital, Shenzhen Eye Medical Center, Southern Medical University, Shenzhen, China