The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC
Year: 2025
Type: article
Language: en
Topic: HIV Research and Treatment
Authors and affiliations:
raw_author_name: Jonathan Richard
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Michael W. Grunst
raw_affiliation_strings: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Ling Niu
raw_affiliation_strings: Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
raw_author_name: Marco A. Díaz-Salinas
raw_affiliation_strings: Department of Microbiology, University of Massachusetts Chan Medical School, Worcester, MA, USA
raw_author_name: Li Zhu
raw_affiliation_strings: Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: William D. Tolbert
raw_affiliation_strings: Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
raw_author_name: Lorie Marchitto
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Fei Zhou
raw_affiliation_strings: Unit on Structural Biology, Division of Basic and Translational Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA
raw_author_name: Catherine Bourassa
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
raw_author_name: Hongil Kim
raw_affiliation_strings: Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Sri Lakshmi Tejaswi Boodapati
raw_affiliation_strings: Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Derek Yang
raw_affiliation_strings: Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Ta Jung Chiu
raw_affiliation_strings: Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Hung-Ching Chen
raw_affiliation_strings: Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Mehdi Benlarbi
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Guillaume Beaudoin-Bussières
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Suneetha Gottumukkala
raw_affiliation_strings: Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
raw_author_name: Wenwei Li
raw_affiliation_strings: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Katrina Dionne
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Étienne Bélanger
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
raw_author_name: Debashree Chatterjee
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
raw_author_name: Halima Medjahed
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada
raw_author_name: Wayne A. Hendrickson
raw_affiliation_strings: Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA
Department of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA
raw_author_name: Joseph Sodroski
raw_affiliation_strings: Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA
Department of Microbiology, Harvard Medical School, Boston, MA, USA
raw_author_name: Zabrina C. Lang
raw_affiliation_strings: Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, USA
raw_author_name: Abraham J. Morton
raw_affiliation_strings: Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, USA
raw_author_name: Rick K. Huang
raw_affiliation_strings: Laboratory of Cell Biology, National Cancer Institute, NIH, Bethesda, USA
raw_author_name: Doreen Matthies
raw_affiliation_strings: Unit on Structural Biology, Division of Basic and Translational Biophysics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA
raw_author_name: Amos B. Smith
raw_affiliation_strings: Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA, USA
raw_author_name: Priti Kumar
raw_affiliation_strings: Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA. priti.kumar@yale.edu
Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: Walther Mothes
raw_affiliation_strings: Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA. walther.mothes@yale.edu
Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA
raw_author_name: James B. Munro
raw_affiliation_strings: Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA. james.munro@umassmed.edu
Department of Microbiology, University of Massachusetts Chan Medical School, Worcester, MA, USA. james.munro@umassmed.edu
Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA
raw_author_name: Marzena Pazgier
raw_affiliation_strings: Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. marzena.pazgier@usuhs.edu
Infectious Diseases Division, Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA
raw_author_name: Andrés Finzi
raw_affiliation_strings: Centre de Recherche du CHUM, Montréal, Québec, Canada. andres.finzi@umontreal.ca
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada. andres.finzi@umontreal.ca
Département de Microbiologie, Infectiologie et Immunologie, Université de Montréal, Montréal, Québec, Canada
Centre de Recherche du CHUM, Montréal, Québec, Canada