Succinate-driven PKM2 succinylation and dimerization accelerates age-associated cardiac fibrosis
Year: 2025
Type: article
Language: en
Topic: Cardiac Fibrosis and Remodeling
Authors and affiliations:
raw_author_name: Ziwen Wang
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China. wangziwen8080@163.com
Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China. wangziwen8080@163.com
Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China. wangziwen8080@163.com
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. wangziwen8080@163.com
Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, China. wangziwen8080@163.com
Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China
Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, China
raw_author_name: Ziyuan Zhang
raw_affiliation_strings: Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Zheng Ping
raw_affiliation_strings: Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China
raw_author_name: Shu Yang
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Yaqi Li
raw_affiliation_strings: Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Ting Jiang
raw_affiliation_strings: Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Xin Zheng
raw_affiliation_strings: Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, China
raw_author_name: Qi Zhang
raw_affiliation_strings: Department of Colorectal Surgery, Cancer Hospital of University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, Zhejiang Province, China
raw_author_name: Zhaochuan Liu
raw_affiliation_strings: Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China
raw_author_name: Xiaoli Zhang
raw_affiliation_strings: Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China
raw_author_name: Zhongyong Jiang
raw_affiliation_strings: Department of Medical Laboratory, Affiliated Cancer Hospital of Chengdu Medical College, Chengdu Seventh People's Hospital, Chengdu, Sichuan Province, China
raw_author_name: Deng Li
raw_affiliation_strings: Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China
Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, China
raw_author_name: Haimei Sun
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Bo Wu
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Deshan Zhou
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China
raw_author_name: Xuebin Cao
raw_affiliation_strings: Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China. caoxb252@163.com
Department of Cardiology and Nephrology, The 82nd Group Army Hospital of PLA (252 Hospital of PLA), Baoding, Hebei Province, China
raw_author_name: Hanping Shi
raw_affiliation_strings: Department of Gastrointestinal Surgery/Department of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing, China. shihp@ccmu.edu.cn
Key Laboratory of Cancer FSMP for State Market Regulation, Beijing, China. shihp@ccmu.edu.cn
Laboratory for Clinical Medicine, Capital Medical University, Beijing, China. shihp@ccmu.edu.cn
National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital, Capital Medical University, Beijing, China. shihp@ccmu.edu.cn
National Clinical Research Center for Geriatric Diseases, Xuanwu Hospital, Capital Medical University, Beijing, China
Laboratory for Clinical Medicine, Capital Medical University, Beijing, China
raw_author_name: Tingyi Sun
raw_affiliation_strings: Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China. styj211@ccmu.edu.cn
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. styj211@ccmu.edu.cn
Beijing Key Laboratory of Cancer Invasion and Metastasis Research, Beijing, China
Department of Histology and Embryology, School of Basic Medical Sciences, Capital Medical University, Beijing, China