HDAC5 deficiency induces intrinsic resistance to KRAS inhibition by disrupting c-Myc acetylation-ubiquitination homeostasis
Year: 2025
Type: article
Language: en
Topic: Histone Deacetylase Inhibitors Research
Authors and affiliations:
raw_author_name: Taoyu Chen
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Haixin Yu
raw_affiliation_strings: Cancer Center
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Keshan Wang
raw_affiliation_strings: Department of Urology, and
Department of Urology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Gengdu Qin
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Yuhan Zhao
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Xueyi Liang
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Yuxuan Li
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Tianhao Zou
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Jiaying Liu
raw_affiliation_strings: Department of Pathology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Jingyuan Zhao
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Zhiqiang Liu
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Ruozheng Wei
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Bo Wang
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Shanmiao Gou
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Tao Yin
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Heshui Wu
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Xin Jin
raw_affiliation_strings: Cancer Center
Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Yingke Zhou
raw_affiliation_strings: Department of Pancreatic Surgery
Sino-German Laboratory of Personalized Medicine for Pancreatic Cancer
Department of Pancreatic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China