Development of a p62 biodegrader for autophagy targeted degradation
Year: 2025
Type: article
Language: en
Topic: Autophagy in Disease and Therapy
Authors and affiliations:
raw_author_name: Zacharias Thiel
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland. zacharias.thiel@novartis.com
raw_author_name: David Marcellin
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Carole Manneville
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Benedikt Goretzki
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Luca Egger
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Rob Maher
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Cambridge, MA, USA
raw_author_name: Noémie Siccardi
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Laura Torres
raw_affiliation_strings: Open Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA
raw_author_name: Alexandra Probst
raw_affiliation_strings: Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA
raw_author_name: Catrin S. Müller
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Nathalie George
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Markus Vogel
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Sabine Sinterhauf
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Alexandra Lavoisier
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Ji-Young Choi
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Laurianne Forcellino
raw_affiliation_strings: Biologics Research Center, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Alexandro Landshammer
raw_affiliation_strings: Disease Area X, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Patrick Hauck
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Celine Be
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Frédéric Villard
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Sascha Gutmann
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Marc Meyer
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Felix Freuler
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Alexandra Hinniger
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: César Fernández
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Suzanne Chau
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Maude Patoor
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Gilles Sansig
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland
raw_author_name: Gabriel Mitchell
raw_affiliation_strings: Open Innovation at Global Health Disease Area, Biomedical Research, Novartis, Emeryville, CA, USA
raw_author_name: Beat Nyfeler
raw_affiliation_strings: Discovery Sciences, Biomedical Research, Novartis, Basel, Switzerland. beat.nyfeler@novartis.com