Cerebral organoids expressing mutant actin genes reveal cellular mechanism underlying microcephaly
Year: 2025
Type: article
Language: en
Topic: Neurogenesis and neuroplasticity mechanisms
Authors and affiliations:
raw_author_name: Indra Niehaus
raw_affiliation_strings: Department of Human Genetics, Hannover Medical School, Hannover, 30626, Germany
Institute for Clinical Genetics, Technische Universität Dresden, and National Cancer Center (NCT) Dresden, Dresden, 01307, Germany
raw_author_name: Michaela Wilsch-Bräuninger
raw_affiliation_strings: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany
raw_author_name: Felipe Mora-Bermúdez
raw_affiliation_strings: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany
raw_author_name: Fabian Rost
raw_affiliation_strings: Technische Universität Dresden, DRESDEN-Concept Genome Center, Center for Molecular and Cellular Bioengineering (CMCB), Dresden, 01307, Germany
raw_author_name: Mihaela Bobic-Rasonja
raw_affiliation_strings: Croatian Institute of Brain Research and Department of Biology, School of Medicine, University of Zagreb, Zagreb, 10000, Croatia
raw_author_name: Velena Radosevic
raw_affiliation_strings: Department of Obstetrics and Gynecology, University Hospital Centre, Zagreb, 10000, Croatia
raw_author_name: Marija Milkovic-Perisa
raw_affiliation_strings: Department of Pathology and Cytology, School of Medicine, University of Zagreb and University Hospital Centre, Zagreb, 10000, Croatia
raw_author_name: Pauline Wimberger
raw_affiliation_strings: Department of Gynecology and Obstetrics, Technische Universität Dresden, and National Cancer Center (NCT) Dresden, Dresden, 01307, Germany
raw_author_name: Mariasavina Severino
raw_affiliation_strings: Neuroradiology Unit, IRCCS Istituto Giannina Gaslini, Genova, 16147, Italy
raw_author_name: Alexandra Haase
raw_affiliation_strings: Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery, REBIRTH - Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, 30625, Germany
Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery, REBIRTH – Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, 30625, Germany
raw_author_name: Ulrich Martin
raw_affiliation_strings: Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery, REBIRTH - Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, 30625, Germany
Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO), Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery, REBIRTH – Research Center for Translational Regenerative Medicine, Hannover Medical School, Hannover, 30625, Germany
raw_author_name: Karolina Kuenzel
raw_affiliation_strings: Institute of Pharmacology and Toxicology, Technische Universität Dresden, 01307, Dresden, Germany
raw_author_name: Kaomei Guan
raw_affiliation_strings: Institute of Pharmacology and Toxicology, Technische Universität Dresden, 01307, Dresden, Germany
raw_author_name: Katrin Neumann
raw_affiliation_strings: Center for Regenerative Therapies Dresden (CRTD, Stem Cell Engineering Facility), Technische Universität Dresden, Dresden, 01307, Germany
raw_author_name: Noreen Walker
raw_affiliation_strings: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany
raw_author_name: Evelin Schröck
raw_affiliation_strings: Institute for Clinical Genetics, Technische Universität Dresden, and National Cancer Center (NCT) Dresden, Dresden, 01307, Germany
raw_author_name: Natasa Jovanov-Milosevic
raw_affiliation_strings: Croatian Institute of Brain Research and Department of Biology, School of Medicine, University of Zagreb, Zagreb, 10000, Croatia. njovanov@hiim.hr
Croatian Institute of Brain Research and Department of Biology, School of Medicine, University of Zagreb, Zagreb, 10000, Croatia
raw_author_name: Wieland B Huttner
raw_affiliation_strings: Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany. huttner@mpi-cbg.de
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany
raw_author_name: Nataliya Di Donato
raw_affiliation_strings: Department of Human Genetics, Hannover Medical School, Hannover, 30626, Germany. didonato.nataliya@mh-hannover.de
Institute for Clinical Genetics, Technische Universität Dresden, and National Cancer Center (NCT) Dresden, Dresden, 01307, Germany. didonato.nataliya@mh-hannover.de
Department of Human Genetics, Hannover Medical School, Hannover, 30626, Germany
Institute for Clinical Genetics, Technische Universität Dresden, and National Cancer Center (NCT) Dresden, Dresden, 01307, Germany
raw_author_name: Michael Heide
raw_affiliation_strings: German Primate Center, Leibniz Institute for Primate Research, Göttingen, 37077, Germany. mheide@dpz.eu
Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, 01307, Germany. mheide@dpz.eu
German Primate Center, Leibniz Institute for Primate Research, Göttingen, 37077, Germany