Somatic evolution following cancer treatment in normal tissue
Year: 2025
Type: article
Language: en
Topic: Cancer Genomics and Diagnostics
Authors and affiliations:
raw_author_name: Oriol Pich
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK. oriol.pich@crick.ac.uk
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK. oriol.pich@crick.ac.uk
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Sophia Ward
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Genomics Science Technology Platform, The Francis Crick Institute, London, UK
raw_author_name: Andrew Rowan
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Cristina Naceur-Lombardelli
raw_affiliation_strings: Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Oliver Shutkever
raw_affiliation_strings: Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
University College London Hospitals, London, UK
raw_author_name: Carlos Martinez-Ruiz
raw_affiliation_strings: Cancer Genome Evolution Research Group, University College London Cancer Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Siân Harries
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Genomics Science Technology Platform, The Francis Crick Institute, London, UK
raw_author_name: Sonya Hessey
raw_affiliation_strings: Cancer Metastasis Laboratory, University College London Cancer Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK
raw_author_name: Babu Naidu
raw_affiliation_strings: Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK
raw_author_name: James D. Brenton
raw_affiliation_strings: Cambridge University Hospital NHS Foundation Trust and National Institute for Health Research Cambridge Biomedical Research Centre, Addenbrooke's Hospital, Cambridge, UK
Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK
Cancer Research UK Major Centre-Cambridge, University of Cambridge, Cambridge, UK
raw_author_name: John Le Quesne
raw_affiliation_strings: Cancer Research UK Scotland Institute, Glasgow, UK
NHS Greater Glasgow and Clyde Pathology Department, Queen Elizabeth University Hospital, Glasgow, UK
School of Cancer Sciences, University of Glasgow, Glasgow, UK
raw_author_name: Anne Thomas
raw_affiliation_strings: Leicester Cancer Research Centre, College of Life Sciences, University of Leicester, Leicester, UK
raw_author_name: Cathy Richards
raw_affiliation_strings: University Hospitals of Leicester NHS Trust, Leicester, UK
raw_author_name: Matthew G. Krebs
raw_affiliation_strings: Division of Cancer Sciences, The University of Manchester, Manchester, UK
National Institute for Health and Care Research (NIHR) Manchester Biomedical Research Centre (BRC), Manchester, UK
The Christie NHS Foundation Trust, Manchester, UK
raw_author_name: Samra Turajlic
raw_affiliation_strings: Cancer Dynamics Laboratory, The CRUK Manchester Institute, Manchester, UK
Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK
The Christie NHS Foundation Trust, Manchester, UK
The Institute of Cancer Research, London, UK
The Royal Marsden Hospital, London, UK
raw_author_name: Sanjay Jogai
raw_affiliation_strings: NIHR Biomedical Research Centre, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK
University Hospital Southampton NHS Trust, Southampton, UK
raw_author_name: Simone Zaccaria
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK
raw_author_name: David Moore
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Department of Cellular Pathology, University College London Hospitals, London, UK
raw_author_name: Crispin T. Hiley
raw_affiliation_strings: University College London Cancer Institute, London, UK
University College London Hospitals, London, UK
raw_author_name: John Le Quesne
raw_affiliation_strings: Cancer Research UK Scotland Institute, Glasgow, UK
NHS Greater Glasgow and Clyde Pathology Department, Queen Elizabeth University Hospital, Glasgow, UK
School of Cancer Sciences, University of Glasgow, Glasgow, UK
raw_author_name: Kai-Keen Shiu
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: John Bridgewater
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Daniel Hochhauser
raw_affiliation_strings: University College London Cancer Institute, London, UK
University College London Hospitals, London, UK
raw_author_name: Martin Forster
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Siow Ming Lee
raw_affiliation_strings: University College London Hospitals, London, UK
University College London Cancer Institute, London, UK
raw_author_name: Tanya Ahmad
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Dionysis Papadatos-Pastos
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Sam Janes
raw_affiliation_strings: UCL Respiratory, Division of Medicine, University College London Hospitals, London, UK
raw_author_name: Peter Van Loo
raw_affiliation_strings: Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Katey Enfield
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Ariana Huebner
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Sergio Quezada
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Stephan Beck
raw_affiliation_strings: Medical Genomics, University College London Cancer Institute, London, UK
raw_author_name: Tariq Enver
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: David R. Pearce
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Mary Falzon
raw_affiliation_strings: Department of Cellular Pathology, University College London Hospitals, London, UK
raw_author_name: Ron Sinclair
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Zoe Rhodes
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Teresa Marafioti
raw_affiliation_strings: Department of Cellular Pathology, University College London Hospitals, London, UK
raw_author_name: Miriam Mitchison
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Mark Linch
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Sebastian Brandner
raw_affiliation_strings: University College London Queen Square Institute of Neurology, London, UK
raw_author_name: Selvaraju Veeriah
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Heather Shaw
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Gerhardt Attard
raw_affiliation_strings: University College London Hospitals, London, UK
University College London Cancer Institute, London, UK
raw_author_name: Faye Gishen
raw_affiliation_strings: UCL Medical School, University College London, London, UK
raw_author_name: Maise Al-Bakir
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Nnenna Kanu
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Francisco Gimeno-Valiente
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Emilia L. Lim
raw_affiliation_strings: The University of British Columbia, Vancouver, British Columbia, Canada
raw_author_name: James Reading
raw_affiliation_strings: Pre-Cancer Immunology Laboratory, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Benny Chain
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Adrienne Flanagan
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Emma Colliver
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Mihaela Angelova
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: James Black
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Olivia Lucas
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
University College London Hospitals, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: William Hill
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Wing Kin Liu
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Alexander Frankell
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Roberto Salgado
raw_affiliation_strings: Division of Research, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Department of Pathology, ZAS Hospitals, Antwerp, Belgium
raw_author_name: Kristiana Grigoriadis
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Takahiro Karasaki
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Abigail Bunkum
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Sarah Benafif
raw_affiliation_strings: University College London Hospitals, London, UK
The Whittington Hospital NHS Trust, London, UK
raw_author_name: Vittorio Barbè
raw_affiliation_strings: Human Biology Facility–Organoids Service, The Francis Crick Institute, London, UK
raw_author_name: Supreet Kaur Bola
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK
raw_author_name: Osvaldas Vainauskas
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Anna Wingate
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Daniel Wetterskog
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: A. M. Mahedi Hasan
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Stefano Lise
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Gianmarco Leone
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Anuradha Jayaram
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Constantine Alifrangis
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Ursula McGovern
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raw_author_name: Kerstin Thol
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raw_author_name: Samuel Gamble
raw_affiliation_strings: Pre-Cancer Immunology Laboratory, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Seng Kuong Ung
raw_affiliation_strings: Pre-Cancer Immunology Laboratory, Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Piotr Pawlik
raw_affiliation_strings: University College London Cancer Institute, London, UK
raw_author_name: Roberto Vendramin
raw_affiliation_strings: Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK
raw_author_name: Jayant Rane
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Angela Dwornik
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK
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raw_author_name: Jeanette Kittel
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Kerstin Haase
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raw_author_name: Rija Zaidi
raw_affiliation_strings: Computational Cancer Genomics Research Group, University College London Cancer Institute, London, UK
raw_author_name: Athanasia Vargiamiou
raw_affiliation_strings: University College London Hospitals, London, UK
raw_author_name: Lucrezia Patruno
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Christopher Aled Chamberlain
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Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Welles Robinson
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK
raw_author_name: Iain McNeish
raw_affiliation_strings: Imperial College London, London, UK
raw_author_name: Nataly Ojeda Mosquera
raw_affiliation_strings: Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK
Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
raw_author_name: Jiali Liu
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raw_author_name: Felix O’Farrell
raw_affiliation_strings: Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, UK
Immune Regulation and Tumour Immunotherapy Group, Cancer Immunology Unit, Research Department of Haematology, University College London Cancer Institute, London, UK
raw_author_name: Chenelle Marcel
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raw_author_name: James Larkin
raw_affiliation_strings: The Royal Marsden Hospital, London, UK
The Institute of Cancer Research, London, UK
raw_author_name: Lisa Pickering
raw_affiliation_strings: The Royal Marsden Hospital, London, UK
raw_author_name: Andrew Furness
raw_affiliation_strings: The Royal Marsden Hospital, London, UK
raw_author_name: Kate Young
raw_affiliation_strings: The Royal Marsden Hospital, London, UK