Asciminib demonstrates superior efficacy and safety in newly diagnosed chronic myeloid leukemia in the ASC4FIRST trial
Year: 2025
Type: article
Language: en
Topic: Chronic Myeloid Leukemia Treatments
Authors and affiliations:
raw_author_name: Jorge E. Cortes
raw_affiliation_strings: 1Department of Medicine, Georgia Cancer Center at Augusta University, Augusta, GA
Georgia Cancer Center, Augusta, Georgia, United States
raw_author_name: Timothy P. Hughes
raw_affiliation_strings: 2Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute and University of Adelaide, Adelaide, Australia
South Australian Health and Medical Research Institute, Adelaide, Australia
raw_author_name: Jianxiang Wang
raw_affiliation_strings: 3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
2. Tianjin Institutes of Health Science, Tianjin 301600, China., Tianjin, China
1. State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China; 2. Tianjin Institutes of Health Science, Tianjin 301600, China., Tianjin, China
raw_author_name: Dong-Wook Kim
raw_affiliation_strings: 4Department of Hematology, Uijeongbu Eulji Medical Center, Uijeongbu-si, Republic of Korea
5Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Canada
Hematology Department, Eulji Medical Center, Eulji University, Leukemia Omics Research Institute, Eulji University, Seoul, Korea, Republic of
raw_author_name: Dennis Dong Hwan Kim
raw_affiliation_strings: 4Department of Hematology, Uijeongbu Eulji Medical Center, Uijeongbu-si, Republic of Korea
5Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto, Canada
Princess Margaret Hospital, Toronto, Ontario, Canada
raw_author_name: Jiri Mayer
raw_affiliation_strings: 6Department of Internal Medicine, Hematology and Oncology, University Hospital Brno and Masaryk University Brno, Brno, Czech Republic
University Hospital Brno, Brno, Czech Republic
raw_author_name: Yeow-Tee Goh
raw_affiliation_strings: 7Department of Hematology, Singapore General Hospital, Singapore
Singapore General Hospital, singapore, Singapore
raw_author_name: Philipp le Coutre
raw_affiliation_strings: 8Department of Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany
Campus Virchow Klinikum, Charité, Berlin, Germany
raw_author_name: Gabriel Etienne
raw_affiliation_strings: 9Hematology Department, Institut Bergonié, Bordeaux, France
Institut Bergonie, Bordeaux, France
raw_author_name: Inho Kim
raw_affiliation_strings: 10Department of Internal Medicine, Seoul National University Hospital, Biomedical Research Institute, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea
Seoul National University Hospital, Seoul, Quebec, Korea, Republic of
raw_author_name: David J. Andorsky
raw_affiliation_strings: 11Rocky Mountain Cancer Centers, Boulder, CO
Sarah Cannon Research Institute at Rocky Mountain Cancer Centers, Boulder, Colorado, United States
raw_author_name: Felice Bombaci
raw_affiliation_strings: 12CML Patients Group, CML Advocates Network, Turin, Italy
CML Patients Group, CML Advocates Network, Bern, Switzerland
raw_author_name: Ghayas C. Issa
raw_affiliation_strings: 13Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
The University of Texas MD Anderson Cancer Center, Houston, Texas, United States
raw_author_name: Naoto Takahashi
raw_affiliation_strings: 14Department of Hematology, Akita University, Akita City, Japan
Akita University Graduate School of Medicine, Akita, Japan
raw_author_name: Shruti Kapoor
raw_affiliation_strings: 15Novartis Pharmaceuticals, East Hanover, NJ
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, United States
raw_author_name: Rajendra Jinwal
raw_affiliation_strings: 16Novartis Pharma AG, Basel, Switzerland
Novartis Healthcare Pvt. Ltd, Basel, Switzerland
raw_author_name: Kamel Malek
raw_affiliation_strings: 16Novartis Pharma AG, Basel, Switzerland
Novartis Pharma AG, Basel, Switzerland
raw_author_name: Tracey McCulloch
raw_affiliation_strings: 16Novartis Pharma AG, Basel, Switzerland
Novartis Pharmaceuticals Corporation, Basel, Switzerland
raw_author_name: Lillian Yau
raw_affiliation_strings: 16Novartis Pharma AG, Basel, Switzerland
Novartis Pharma AG, Basel, Switzerland
raw_author_name: Richard A. Larson
raw_affiliation_strings: 17Department of Medicine, The University of Chicago, Chicago, IL
University of Chicago, Chicago, Illinois, United States
raw_author_name: Andreas Hochhaus
raw_affiliation_strings: 18Department of Hematology/Oncology, Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Germany
Universitätsklinikum Jena, Jena, Germany