mTOR signaling during T cell activation promotes cytokine production in T cells through 3′ UTR-mediated translation control
Year: 2025
Type: article
Language: en
Topic: PI3K/AKT/mTOR signaling in cancer
Authors and affiliations:
raw_author_name: Anouk P. Jurgens
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Josephine Zwijnen
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Antonia Bradarić
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Floris P.J. van Alphen
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, Bleeding & Hemostasis, Plesmanlaan 125, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands
raw_author_name: Kaspar Bresser
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Koos Rooijers
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Arie J. Hoogendijk
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, Bleeding & Hemostasis, Plesmanlaan 125, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands
raw_author_name: Branka Popović
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands
raw_author_name: Monika C. Wolkers
raw_affiliation_strings: Sanquin Blood Supply Foundation, Department of Research, T-cell Differentiation Lab, Plesmanlaan 125, 1066 CX, Amsterdam, the Netherlands; Amsterdam UMC, University of Amsterdam, Landsteiner Laboratory, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Amsterdam Institute for Infection & Immunity, and Cancer Center Amsterdam - Cancer Immunology, Amsterdam, the Netherlands; Oncode Institute, Utrecht, the Netherlands. Electronic address: m.wolkers@sanquin.nl