Cardiovascular–kidney–metabolic syndrome and the risk of liver fibrosis progression and liver-related events in MASLD
Year: 2025
Type: article
Language: en
Topic: Liver Disease Diagnosis and Treatment
Authors and affiliations:
raw_author_name: Xiao-Dong Zhou
raw_affiliation_strings: MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Qin-Fen Chen
raw_affiliation_strings: Institute of Aging, The Center for Geriatric Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Medical Care Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Qiong-Yue Fan
raw_affiliation_strings: MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Seung Up Kim
raw_affiliation_strings: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
raw_author_name: Terry Cheuk-Fung Yip
raw_affiliation_strings: Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Salvatore Petta
raw_affiliation_strings: Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Palermo, Italy
Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Italy
raw_author_name: Atsushi Nakajima
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
raw_author_name: Emmanuel Tsochatzis
raw_affiliation_strings: University College London Institute for Liver and Digestive Health, Royal Free Hospital, London, UK
University College London Institute for Liver and Digestive Health, Royal Free Hospital, London, United Kingdom
raw_author_name: Jérôme Boursier
raw_affiliation_strings: Department of Hepato-Gastroenterology and Digestive Oncology, Angers University Hospital, Angers, France
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Elisabetta Bugianesi
raw_affiliation_strings: Division of Gastroenterology and Hepatology, Department of Medical Sciences, A.O. Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy
Department of Medical Sciences, Division of Gastroenterology and Hepatology, A.O. Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy
raw_author_name: Hannes Hagström
raw_affiliation_strings: Department of Medicine, Karolinska Institutet, Huddinge, Sweden
Division of Hepatology, Department of Upper Gastrointestinal Diseases, Karolinska University Hospital, Stockholm, Sweden
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Institute of Aging, The Center for Geriatric Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Wah-Kheong Chan
raw_affiliation_strings: Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Malaysia
raw_author_name: Manuel Romero-Gomez
raw_affiliation_strings: UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Seville, Spain
UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Spain
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: José Luis Calleja
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Victor de Lédinghen
raw_affiliation_strings: Echosens, Paris, France
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Italy
raw_author_name: Laurent Castéra
raw_affiliation_strings: Université Paris Cité, UMR1149 (CRI), INSERM, Paris, France; Service d’Hépatologie, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris (AP-HP), Clichy, France
Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Arun J. Sanyal
raw_affiliation_strings: Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
University College London Institute for Liver and Digestive Health, Royal Free Hospital, London, United Kingdom
Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
raw_author_name: George Boon-Bee Goh
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Philip Noel Newsome
raw_affiliation_strings: Institute of Hepatology, Faculty of Life Sciences & Medicine, King’s College London and King’s College Hospital, London, UK
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Jian-Gao Fan
raw_affiliation_strings: Department of Gastroenterology and Hepatology, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Michelle Lai
raw_affiliation_strings: Division of Gastroenterology & Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Céline Fournier-Poizat
raw_affiliation_strings: Echosens, Paris, France
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Italy
raw_author_name: Hye Won Lee
raw_affiliation_strings: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
raw_author_name: Grace Lai-Hung Wong
raw_affiliation_strings: Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Angelo Armandi
raw_affiliation_strings: Division of Gastroenterology and Hepatology, Department of Medical Sciences, A.O. Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy
Department of Medical Sciences, Division of Gastroenterology and Hepatology, A.O. Città della Salute e della Scienza di Torino, University of Turin, Turin, Italy
raw_author_name: Ying Shang
raw_affiliation_strings: Department of Medicine, Karolinska Institutet, Huddinge, Sweden
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Grazia Pennisi
raw_affiliation_strings: Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Palermo, Italy
Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Italy
raw_author_name: Elba Llop
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Masato Yoneda
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
raw_author_name: Marc de Saint-Loup
raw_affiliation_strings: Department of Hepato-Gastroenterology and Digestive Oncology, Angers University Hospital, Angers, France
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Clemence M. Canivet
raw_affiliation_strings: Department of Hepato-Gastroenterology and Digestive Oncology, Angers University Hospital, Angers, France
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Paloma Carrillo-Fernandez
raw_affiliation_strings: UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Seville, Spain
UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Spain
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Carmen Lara-Romero
raw_affiliation_strings: UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Seville, Spain
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Spain
raw_author_name: Rocio Gallego-Durán
raw_affiliation_strings: UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Seville, Spain
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
UCM Digestive Diseases, Virgen del Rocío University Hospital, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institute of Biomedicine of Seville (IBiS), University of Seville, Spain
raw_author_name: Amon Asgharpour
raw_affiliation_strings: Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA
University College London Institute for Liver and Digestive Health, Royal Free Hospital, London, United Kingdom
Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA
raw_author_name: Kevin Kim-Jun Teh
raw_affiliation_strings: Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Mandy Sau-Wai Chan
raw_affiliation_strings: Echosens, Paris, France
Sezione di Gastroenterologia, Di.Bi.M.I.S., University of Palermo, Italy
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: Huapeng Lin
raw_affiliation_strings: Center for Digestive Diseases Research and Clinical Translation, Shanghai Jiao Tong University, Shanghai, China
Department of Gastroenterology and Hepatology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Key Laboratory of Gut Microecology and Associated Major Diseases, Shanghai, China
Department of Gastroenterology and Hepatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Shanghai Key Laboratory of Gut Microecology and Associated Major Diseases Research, Shanghai, China
raw_author_name: Wen-Yue Liu
raw_affiliation_strings: Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Medical Care Center, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
Department of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan
raw_author_name: Giovanni Targher
raw_affiliation_strings: Department of Medicine, University of Verona, Verona, Italy
Metabolic Diseases Research Unit, IRCCS Sacro Cuore–Don Calabria Hospital, Negrar di Valpolicella, Italy
University College London Institute for Liver and Digestive Health, Royal Free Hospital, London, United Kingdom
Institute of Aging, The Center for Geriatric Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China
raw_author_name: Christopher D. Byrne
raw_affiliation_strings: Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton and University of Southampton, Southampton General Hospital, Southampton, UK
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton, and University of Southampton, Southampton General Hospital, Southampton, UK
raw_author_name: Vincent Wai-Sun Wong
raw_affiliation_strings: Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong SAR, China
Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
raw_author_name: Ming-Hua Zheng
raw_affiliation_strings: Institute of Hepatology, Wenzhou Medical University, Wenzhou, China
Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China
MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
raw_author_name: and the VCTE-Prognosis Study Group