Identification and characterization of binders to a cryptic and functional pocket in KRAS
Year: 2025
Type: article
Language: en
Topic: Protein Kinase Regulation and GTPase Signaling
Authors and affiliations:
raw_author_name: Kim S. Beyer
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Jessica Klein
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Stéphanie Katz
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Patrick Welker
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Mylene Lanter
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Daniel Guthy
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Kerstin Pollehn
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Aurélie Gluck-Gadé
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Melusine Bleu
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Jessica Desogus
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Marc Hattenberger
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Damiano Borrello
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
Procter and Gamble, Patent Department, Brussels, Belgium
raw_author_name: Wassim Abdul Rahman
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Florence Zink
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Nils Ostermann
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Wolfgang Jahnke
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Christoph E. Dumelin
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Lukas Leder
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Oliver Esser
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Lionel Muller
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Andreas Marzinzik
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Regis Cébé
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Kathrin Müller
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Giorgio G. Galli
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Luca Tordella
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Simona Cotesta
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Saskia M. Brachmann
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland
raw_author_name: Sauveur-Michel Maira
raw_affiliation_strings: Novartis Biomedical Research, Basel, Switzerland. michel.maira@novartis.com
Novartis Biomedical Research, Basel, Switzerland