Efficacy of isoniazid in paediatric tuberculosis: an individual participant data meta-analysis
Year: 2025
Type: article
Language: en
Topic: Tuberculosis Research and Epidemiology
Authors and affiliations:
raw_author_name: Agathe Béranger
raw_affiliation_strings: A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors
Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA
Réanimation et Soins Intensifs Polyvalents Pédiatriques - SMUR Pédiatrique, AP-HP.Centre - Université de Paris Cité, Hôpital Necker Enfants Malades, Paris, France
UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA
Université Paris Cité, INSERM, UMR1343, Pharmacologie et Evaluation des Thérapeutiques chez l'Enfant et la Femme Enceinte, Paris, France
1Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, United States of America
raw_author_name: Belén P. Solans
raw_affiliation_strings: A. Béranger and B.P. Solans are equal contributors to this work and designated as co-first authors
Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA
UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA
1Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, United States of America
raw_author_name: Ryo Miyakawa
raw_affiliation_strings: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA
UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA
1Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, United States of America
raw_author_name: Helen McIlleron
raw_affiliation_strings: Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
5Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa
raw_author_name: Joel Tarning
raw_affiliation_strings: Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
6Mahidol-Oxford Tropical Medicine Research Unit, Faculty of tropical medicine, Mahidol University, Bangkok, Thailand
raw_author_name: Ira Shah
raw_affiliation_strings: Pediatric DR-TB Center of Excellence (State), Department of Pediatric Infectious Diseases, B.J. Wadia Hospital for Children, Mumbai, India
8Pediatric DR-TB Center of Excellence (State), Department of Pediatric Infectious Diseases, B J Wadia Hospital for Children, Mumbai, India
raw_author_name: Blessed Winston Aruldhas
raw_affiliation_strings: Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India
9Department of Pharmacology & Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India
raw_author_name: Binu Susan Mathew
raw_affiliation_strings: Department of Pharmacology and Clinical Pharmacology, Christian Medical College, Vellore, India
9Department of Pharmacology & Clinical Pharmacology, Christian Medical College, Vellore, Tamil Nadu, India
raw_author_name: Awewura Kwara
raw_affiliation_strings: Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA
10Department of Medicine, University of Florida College of Medicine, Gainesville, USA
raw_author_name: Charles A. Peloquin
raw_affiliation_strings: Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA
11Department of Pharmacotherapy & Translational Research, College of Pharmacy, University of Florida, USA
raw_author_name: Aparna Mukherjee
raw_affiliation_strings: Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India
12Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
raw_author_name: Rakesh Lodha
raw_affiliation_strings: Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, India
12Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
raw_author_name: Paolo Denti
raw_affiliation_strings: Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa
5Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa
raw_author_name: Edmund V. Capparelli
raw_affiliation_strings: Pediatrics Department, Rady Children's Hospital San Diego, University of California San Diego, La Jolla, CA, USA
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA
13Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, United States of America
raw_author_name: Jennifer J. Kiser
raw_affiliation_strings: Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz, Aurora, CO, USA
15Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
raw_author_name: Adrie Bekker
raw_affiliation_strings: Family Centre for Research with Ubuntu, Department of Paediatric and Child Health, Stellenbosch University, Cape Town, South Africa
16Family Centre for Research with Ubuntu, Department of Paediatric and Child Health, Stellenbosch University, Cape Town, South Africa
raw_author_name: Chishala Chabala
raw_affiliation_strings: Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia
University Teaching Hospital, Children's Hospital, Lusaka, Zambia
17Department of Paediatrics and Child Health, School of Medicine, University of Zambia, Lusaka, Zambia
raw_author_name: Louise Choo
raw_affiliation_strings: Medical Research Council Clinical Trials Unit, University College London, London, UK
19Medical Research Council Clinical Trials Unit at University College London, London, United Kingdom
raw_author_name: Anna Turkova
raw_affiliation_strings: Medical Research Council Clinical Trials Unit, University College London, London, UK
19Medical Research Council Clinical Trials Unit at University College London, London, United Kingdom
raw_author_name: Fajri Gafar
raw_affiliation_strings: Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
McGill International TB Centre, McGill University, Montreal, QC, Canada
Respiratory Epidemiology and Clinical Research Unit, Centre for Outcomes Research and Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Unit of PharmacoTherapy, -Epidemiology and -Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands
20Unit of PharmacoTherapy, -Epidemiology and -Economics, Groningen Research Institute of Pharmacy, Univeristy of Groningen, Groningen, The Netherlands
raw_author_name: Rovina Ruslami
raw_affiliation_strings: Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
McGill International TB Centre, McGill University, Montreal, QC, Canada
21Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
raw_author_name: Heda M. Nataprawira
raw_affiliation_strings: Division of Pediatric Respirology, Department of Child Health, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia
24Division of Pediatric Respirology, Department of Child Health, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjadjaran, Indonesia
raw_author_name: Scott K. Heysell
raw_affiliation_strings: Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA
25Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA
raw_author_name: Tania A. Thomas
raw_affiliation_strings: Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, VA, USA
25Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA
raw_author_name: Thirumurthy Velpandian
raw_affiliation_strings: Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
26Department of Ocular Pharmacology & Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
raw_author_name: Jeremy N. Day
raw_affiliation_strings: Department of Clinical Microbiology and Infection, Royal Devon and Exeter University Hospital NHS Trust, Exeter, UK
27Department of Clinical Microbiology and Infection, Royal Devon and Exeter University Hospital NHS Trust, Exeter, United Kingdom
raw_author_name: Nguyen Duc Bang
raw_affiliation_strings: Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease, Ho Chi Minh City, Vietnam
28Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease, Ho Chi Minh City, Vietnam
raw_author_name: Kelly Dooley
raw_affiliation_strings: Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA
29Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, USA
raw_author_name: Radojka M. Savic
raw_affiliation_strings: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA rada.savic@ucsf.edu
UCSF Center for Tuberculosis, University of California San Francisco, San Francisco, CA, USA
1Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, United States of America