Histone deacetylase SIRT6 regulates tryptophan catabolism and prevents metabolite imbalance associated with neurodegeneration
Year: 2025
Type: article
Language: en
Topic: Sirtuins and Resveratrol in Medicine
Authors and affiliations:
raw_author_name: Shai Kaluski-Kopatch
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Daniel Stein
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Alfredo Garcia Venzor
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Ana Margarida Ferreira Campos
raw_affiliation_strings: Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium
Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium
raw_author_name: Melanie Planque
raw_affiliation_strings: Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium
Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium
raw_author_name: Bareket Goldstein
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Estefanía De Allende-Becerra
raw_affiliation_strings: Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Dmitrii Smirnov
raw_affiliation_strings: Center for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Moscow, Russia
Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Adam Zaretsky
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Ekaterina Eremenko
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Miguel Portillo
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Monica Einav
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Alena Bruce Krejci
raw_affiliation_strings: Faculty of Science, University of South Bohemia, Ceske Budejovice, Czechia
raw_author_name: Uri Abdu
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Ekaterina Khrameeva
raw_affiliation_strings: Center for Molecular and Cellular Biology, Skolkovo Institute of Science and Technology, Moscow, Russia
raw_author_name: Daniel Gitler
raw_affiliation_strings: Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel
raw_author_name: Sarah-Maria Fendt
raw_affiliation_strings: Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium
Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium
raw_author_name: Debra Toiber
raw_affiliation_strings: Department of Life Sciences, Faculty of Natural Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel. toiber@bgu.ac.il
School of Brain Sciences and Cognition, Ben-Gurion University of the Negev, Beer Sheva, Israel. toiber@bgu.ac.il