A fully iPS-cell-derived 3D model of the human blood–brain barrier for exploring neurovascular disease mechanisms and therapeutic interventions
Year: 2025
Type: article
Language: en
Topic: Barrier Structure and Function Studies
Authors and affiliations:
raw_author_name: Judit González-Gallego
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Katalin Todorov-Völgyi
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Stephan A. Müller
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany
Neuroproteomics, School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
raw_author_name: Sophie Antesberger
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Mihail Ivilinov Todorov
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Center Munich, Neuherberg, Germany
raw_author_name: Rainer Malik
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Rita Grimalt-Mirada
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Carolina Cardoso Gonçalves
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Martina Schifferer
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
raw_author_name: Georg Kislinger
raw_affiliation_strings: Institute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany
raw_author_name: Isabel Weisheit
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Barbara Lindner
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Dennis Crusius
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Joseph Kroeger
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Mila Borri
raw_affiliation_strings: Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
raw_author_name: Ali Erturk
raw_affiliation_strings: Deep Piction, Munich, Germany
Institute for Intelligent Biotechnologies (iBIO), Helmholtz Center Munich, Neuherberg, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
School of Medicine, Koç University, Istanbul, Turkey
raw_author_name: Mark Nelson
raw_affiliation_strings: Department of Pharmacology, University of Vermont, Burlington, VT, USA
Division of Cardiovascular Sciences, University of Manchester, Manchester, UK
raw_author_name: Thomas Misgeld
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany
Institute of Neuronal Cell Biology, Technical University of Munich, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
raw_author_name: Stefan F. Lichtenthaler
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
Neuroproteomics, School of Medicine and Health, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
raw_author_name: Martin Dichgans
raw_affiliation_strings: German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany. Martin.Dichgans@med.uni-muenchen.de
German Centre for Cardiovascular Research (DZHK), Munich, Germany. Martin.Dichgans@med.uni-muenchen.de
Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany. Martin.Dichgans@med.uni-muenchen.de
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany. Martin.Dichgans@med.uni-muenchen.de
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. Martin.Dichgans@med.uni-muenchen.de
German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany
raw_author_name: Dominik Paquet
raw_affiliation_strings: Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany. dominik.paquet@med.uni-muenchen.de
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany. dominik.paquet@med.uni-muenchen.de
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany. dominik.paquet@med.uni-muenchen.de
Graduate School of Systemic Neuroscience (GSN), LMU Munich, Munich, Germany
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany