HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion
Year: 2025
Type: article
Language: en
Topic: Extracellular vesicles in disease
Authors and affiliations:
raw_author_name: Yoav Chemla
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Orit Itzhaki
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel; Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Ramat Gan 52621, Israel
raw_author_name: Stav Melamed
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Chen Weller
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Yuval Sade
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Paulee Manich
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Keren Reshef
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Nicolas Xenidis
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Avishai Maliah
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Gilad Levy
raw_affiliation_strings: Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Roma Parikh
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Osnat Bartok
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Opal Levy
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Itay Tal
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Gal Aziel
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Abraham Nissani
raw_affiliation_strings: Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Ramat Gan 52621, Israel
raw_author_name: Sharon Yunger
raw_affiliation_strings: Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Ramat Gan 52621, Israel
raw_author_name: Daniela Likonen
raw_affiliation_strings: Department of Dermatology, Sheba Medical Center, Ramat Gan, Israel
raw_author_name: Vitaly Kliminsky
raw_affiliation_strings: Department of Dermatology, Sheba Medical Center, Ramat Gan, Israel
raw_author_name: Tamar Golan
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Coralie Capron
raw_affiliation_strings: Laboratory of Cancer Stemness, GIGA Institute, University of Liège, Liège, Belgium
raw_author_name: Valentina Ace
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Ronen Levy
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Diana Rasoulouniriana
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Zohar Eyal
raw_affiliation_strings: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
raw_author_name: Yuval Barzilay
raw_affiliation_strings: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
raw_author_name: Roi Balaban
raw_affiliation_strings: Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Aseel Khateeb
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Rami Khosravi
raw_affiliation_strings: Single Cell Genomics Core, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Amir Grau
raw_affiliation_strings: Biomedical Core Facility, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
raw_author_name: Tamar Ziv
raw_affiliation_strings: Smoler Proteomics Center, Lokey Interdisciplinary Center for Life Sciences & Engineering, Technion-Israel Institute of Technology, Haifa, Israel
raw_author_name: Polina Greenberg
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Dvir Netanely
raw_affiliation_strings: Blavatnik School of Computer Science and Artificial Intelligence, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Hananya Vaknin
raw_affiliation_strings: Institute of Oncology, E. Wolfson Medical Center, Holon, Israel
raw_author_name: Xunwei Wu
raw_affiliation_strings: Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA
raw_author_name: Yael Amitay
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Tel Aviv, Israel
raw_author_name: Ronen Brenner
raw_affiliation_strings: Institute of Oncology, E. Wolfson Medical Center, Holon, Israel
raw_author_name: Julia María Martínez Gómez
raw_affiliation_strings: Laboratory of Cancer Stemness, GIGA Institute, University of Liège, Liège, Belgium
raw_author_name: Dov Hershkovitz
raw_affiliation_strings: Institute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
raw_author_name: Tal Yardeni
raw_affiliation_strings: Metabolic Center, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel
raw_author_name: Valentina Zemser-Werner
raw_affiliation_strings: Institute of Pathology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
raw_author_name: Oren Kobiler
raw_affiliation_strings: Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Yael Friedmann
raw_affiliation_strings: Bio-Imaging Unit, Hebrew University, Jerusalem 91904, Israel
raw_author_name: David Bassan
raw_affiliation_strings: Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Ron Shamir
raw_affiliation_strings: Blavatnik School of Computer Science and Artificial Intelligence, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Lea Eisenbach
raw_affiliation_strings: Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel
raw_author_name: Nadine Santana-Magal
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Michael Milyavsky
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel
raw_author_name: Galit Eisenberg
raw_affiliation_strings: Hadassah Cancer Research Institute, Hadassah Hebrew University Hospital, Jerusalem, Israel
raw_author_name: Leeat Keren
raw_affiliation_strings: Department of Molecular Cell Biology, Weizmann Institute of Science, Tel Aviv, Israel
raw_author_name: Merav Cohen
raw_affiliation_strings: Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Dvir Gur
raw_affiliation_strings: Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel
raw_author_name: Boaz Barak
raw_affiliation_strings: Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel; The School of Psychological Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Michal Lotem
raw_affiliation_strings: Hadassah Cancer Research Institute, Hadassah Hebrew University Hospital, Jerusalem, Israel
raw_author_name: David Sprinzak
raw_affiliation_strings: School of Neurobiology, Biochemistry and Biophysics, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel
raw_author_name: Shoshana Greenberger
raw_affiliation_strings: Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: David Fisher
raw_affiliation_strings: Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA
raw_author_name: Michal J. Besser
raw_affiliation_strings: Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Ramat Gan 52621, Israel; Department of Clinical Microbiology and Immunology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel; Samueli Integrative Pioneering Institute and Davidoff Center, Rabin Medical Center, Petach Tikva, Israel; Felsenstein Cancer Research Center, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel
raw_author_name: Mehdi Khaled
raw_affiliation_strings: Gustave Roussy Cancer Campus, INSERM U1015, Universite Paris-Saclay, 114 rue Edouard Vaillant, 94800 Villejuif, France. Electronic address: mehdi.khaled@gustaveroussy.fr
raw_author_name: Pierre Close
raw_affiliation_strings: Laboratory of Cancer Signaling, GIGA Institute, University of Liège, Liège, Belgium. Electronic address: pierre.close@uliege.be
raw_author_name: Ronnie Shapira
raw_affiliation_strings: Ella Lemelbaum Institute for Immuno-Oncology and Melanoma, Sheba Medical Center, Ramat Gan 52621, Israel. Electronic address: ronnie.shapira@sheba.health.gov.il
raw_author_name: Sebastien Apcher
raw_affiliation_strings: Gustave Roussy Cancer Campus, INSERM U1015, Universite Paris-Saclay, 114 rue Edouard Vaillant, 94800 Villejuif, France. Electronic address: sebastien.apcher@gustaveroussy.fr
raw_author_name: Asaf Madi
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: asafmadi@tauex.tau.ac.il
raw_author_name: Mitchell P. Levesque
raw_affiliation_strings: University of Zurich, Faculty of Medicine, University Hospital of Zurich, Department of Dermatology, Schlieren 8952, Switzerland. Electronic address: mitchell.levesque@usz.ch
raw_author_name: Francesca Rapino
raw_affiliation_strings: Laboratory of Cancer Stemness, GIGA Institute, University of Liège, Liège, Belgium. Electronic address: francesca.rapino@uliege.be
raw_author_name: Yaron Carmi
raw_affiliation_strings: Department of Pathology, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: yaroncarmi@gmail.com
raw_author_name: Shivang Parikh
raw_affiliation_strings: Department of Human Genetics and Biochemistry, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 69978, Israel; Ragon Institute of Mass General, MIT and Harvard, Cambridge, MA, USA. Electronic address: ssparikh@mgh.harvard.edu
raw_author_name: Yardena Samuels
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raw_author_name: Carmit Levy
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