A preclinical randomised controlled dose optimization of megadose sodium ascorbate for reversal of gram-negative sepsis-induced cardiovascular, brain and kidney dysfunction
Year: 2025
Type: article
Language: en
Topic: Vitamin C and Antioxidants Research
Authors and affiliations:
raw_author_name: Connie Pei Chen Ow
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
raw_author_name: Rachel M. Peiris
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
raw_author_name: Anton Trask-Marino
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
raw_author_name: Sally G. Hood
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
raw_author_name: Ashenafi H. Betrie
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
Translational Neurodegeneration Laboratory, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia
raw_author_name: Darius J. R. Lane
raw_affiliation_strings: Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
Translational Neurodegeneration Laboratory, Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia
raw_author_name: Rinaldo Bellomo
raw_author_name: Mark P. Plummer
raw_affiliation_strings: Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia
Department of Intensive Care, Royal Adelaide Hospital, Adelaide, Australia
raw_author_name: Clive N. May
raw_affiliation_strings: Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia
Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia
raw_author_name: Yugeesh R. Lankadeva
raw_affiliation_strings: Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, VIC, Australia. yugeesh.lankadeva@florey.edu.au
Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia. yugeesh.lankadeva@florey.edu.au