Direct-to-Biology Enabled Molecular Glue Discovery
Year: 2025
Type: article
Language: en
Topic: Chemical Synthesis and Analysis
Authors and affiliations:
raw_author_name: Maowei Hu
raw_affiliation_strings: Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Jason Ochoada
raw_affiliation_strings: Lead Discovery Informatics Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Marisa Actis
raw_affiliation_strings: St Jude Children’s Research Hospital
Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics
raw_author_name: Kevin McGowan
raw_affiliation_strings: Medicinal Chemistry Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Jamie A. Jarusiewicz
raw_affiliation_strings: St Jude Children’s Research Hospital
Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics
raw_author_name: Satoshi Yoshimura
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences
St Jude Children’s Research Hospital
raw_author_name: Logan McGrath
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences
St Jude Children’s Research Hospital
raw_author_name: Uma Neelakantan
raw_affiliation_strings: Center of Excellence for Data Driven Discovery, Department of Structural Biology
Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Anup Aggarwal
raw_affiliation_strings: St Jude Children’s Research Hospital
Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics
raw_author_name: Anand Mayasundari
raw_affiliation_strings: St Jude Children’s Research Hospital
Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics
raw_author_name: Sarah M. Young
raw_affiliation_strings: Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Meng Zhang
raw_affiliation_strings: Center of Excellence for Data Driven Discovery, Department of Structural Biology
St Jude Children’s Research Hospital
raw_author_name: Lei Yang
raw_affiliation_strings: Analytical Technologies Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Yong Li
raw_affiliation_strings: Analytical Technologies Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Shea Mercer
raw_affiliation_strings: Program Management, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: M. Madan Babu
raw_affiliation_strings: Center of Excellence for Data Driven Discovery, Department of Structural Biology
St Jude Children’s Research Hospital
raw_author_name: Marcus Fischer
raw_affiliation_strings: Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Brandon M. Young
raw_affiliation_strings: Medicinal Chemistry Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Jun J. Yang
raw_affiliation_strings: Department of Pharmacy and Pharmaceutical Sciences
St Jude Children’s Research Hospital
raw_author_name: Gisele Nishiguchi
raw_affiliation_strings: St Jude Children’s Research Hospital
Targeted Protein Degradation Center, Department of Chemical Biology and Therapeutics
raw_author_name: Anang A. Shelat
raw_affiliation_strings: Lead Discovery Informatics Center, Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital
raw_author_name: Daniel J. Blair
raw_affiliation_strings: Department of Chemical Biology and Therapeutics
St Jude Children’s Research Hospital