Targeting PRDX6-dependent localization and function of GPX4 enhances ferroptosis-mediated tumor suppression
Year: 2025
Type: article
Language: en
Topic: Ferroptosis and cancer prognosis
Authors and affiliations:
raw_author_name: Yameng Hu
raw_affiliation_strings: Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Diseases, State Key Laboratory of Respiratory Disease, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China; Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Ziwen Li
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Man Li
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Xingui Wu
raw_affiliation_strings: Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Diseases, State Key Laboratory of Respiratory Disease, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China
raw_author_name: Shuxia Zhang
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Miaoling Tang
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Ruyuan Yu
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Meisongzhu Yang
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
raw_author_name: Xin Chen
raw_affiliation_strings: Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Diseases, State Key Laboratory of Respiratory Disease, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China
raw_author_name: Libing Song
raw_affiliation_strings: State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
raw_author_name: Guido Kroemer
raw_affiliation_strings: Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Université de Paris Cité, Sorbonne Université, INSERM U1138, Institut Universitaire de France, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, 94800 Villejuif, France; Department of Biology, Institut du Cancer Paris CARPEM, Hôpital Européen Georges Pompidou, AP-HP, 75015 Paris, France
raw_author_name: Valerian E. Kagan
raw_affiliation_strings: Department of Environmental Health, University of Pittsburgh, Pittsburgh, PA, USA
raw_author_name: Hülya Bayir
raw_affiliation_strings: Department of Pediatrics, Columbia University, New York, NY, USA
raw_author_name: Rui Kang
raw_affiliation_strings: Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA
raw_author_name: Jinbao Liu
raw_affiliation_strings: Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Diseases, State Key Laboratory of Respiratory Disease, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China. Electronic address: jliu@gzhmu.edu.cn
raw_author_name: Daolin Tang
raw_affiliation_strings: Department of Surgery, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address: daolin.tang@utsouthwestern.edu
raw_author_name: Jun Li
raw_affiliation_strings: Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China. Electronic address: lijun37@mail.sysu.edu.cn