Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates
Year: 2025
Type: article
Language: en
Topic: Parkinson's Disease Mechanisms and Treatments
Authors and affiliations:
raw_author_name: Fei Wang
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Victor Banerjee
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Carla Barria
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Santiago Ramirez
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Tyler Allison
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
UTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Damian Gorski
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
UTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
raw_author_name: Haley Evans
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Quynh Nguyen
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Danielle Harrison
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Rabab Al-Lahham
raw_affiliation_strings: Department of Pharmacology and Toxicology, The University of Texas Medical Branch at Galveston, Galveston, TX, USA
Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Nicole De Gregorio Carbonell
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Michelle Pinho
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Sanne Kaalund
raw_affiliation_strings: Centre for Neuroscience and Stereology, Department of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Copenhagen, DK, Denmark
raw_author_name: Jonas Folke
raw_affiliation_strings: Centre for Neuroscience and Stereology, Department of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Copenhagen, DK, Denmark
raw_author_name: Susana Aznar
raw_affiliation_strings: Centre for Neuroscience and Stereology, Department of Neurology, Copenhagen University Hospital, Bispebjerg and Frederiksberg Hospital, Copenhagen, DK, Denmark
raw_author_name: Luis Concha-Marambio
raw_affiliation_strings: Amprion Inc, San Diego, USA, CA
raw_author_name: Mohd Ishtikhar
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Venkata KPS Mallampalli
raw_affiliation_strings: Structural Biology Imaging Center, Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Sandra Pritzkow
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Mohammad Shahnawaz
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Matthew L. Baker
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Irina Serysheva
raw_affiliation_strings: Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
Structural Biology Imaging Center, Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston, Houston, TX, USA
raw_author_name: Claudio Soto
raw_affiliation_strings: Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA. Claudio.Soto@uth.tmc.edu
Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas McGovern Medical School at Houston, Houston, TX, USA