Standardized metrics for assessment and reproducibility of imaging-based spatial transcriptomics datasets
Year: 2025
Type: article
Language: en
Topic: Single-cell and spatial transcriptomics
Authors and affiliations:
raw_author_name: Jasmine T. Plummer
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA. jasmine.plummer@stjude.org
Comprehensive Cancer Center, St. Jude Children's Research Hospital, Memphis, TN, USA. jasmine.plummer@stjude.org
Department of Cellular and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. jasmine.plummer@stjude.org
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. jasmine.plummer@stjude.org
Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Felipe Segato Dezem
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: David P. Cook
raw_affiliation_strings: Cancer Therapeutics Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada
raw_author_name: Jiwoon Park
raw_affiliation_strings: Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, USA
The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA
Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA
raw_author_name: Luke Zhang
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Yutian Liu
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Maycon Marção
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Hannah DuBose
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Arjumand Wani
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Kellie Wise
raw_affiliation_strings: Adelaide Centre for Epigenetics, Adelaide, South Australia, Australia
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
The University of Adelaide, Adelaide, South Australia, Australia
raw_author_name: Michael Roach
raw_affiliation_strings: Adelaide Centre for Epigenetics, Adelaide, South Australia, Australia
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
The University of Adelaide, Adelaide, South Australia, Australia
raw_author_name: Kate Harvey
raw_affiliation_strings: Cancer Ecosystems Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
raw_author_name: Taopeng Wang
raw_affiliation_strings: Cancer Ecosystems Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales Sydney, Sydney, New South Wales, Australia
raw_author_name: Kirk B. Jensen
raw_affiliation_strings: Adelaide Centre for Epigenetics, Adelaide, South Australia, Australia
Australian Genome Research Facility, Adelaide, South Australia, Australia
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
The University of Adelaide, Adelaide, South Australia, Australia
raw_author_name: Natalia Morosini
raw_affiliation_strings: Center for Spatial Omics, St. Jude Children's Research Hospital, Memphis, TN, USA
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA
raw_author_name: Roberto De Gregorio
raw_affiliation_strings: Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Alicia Alonso
raw_affiliation_strings: Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
Department of Medicine, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Shauna Lee Houlihan
raw_affiliation_strings: Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Robert E. Schwartz
raw_affiliation_strings: Department of Medicine, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Erika Hissong
raw_affiliation_strings: Department of Pathology, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Catherine Snopkowski
raw_affiliation_strings: Single-cell Analytics Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY, USA
raw_author_name: Jeffrey L. Wrana
raw_affiliation_strings: Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada
raw_author_name: Natalie Ryan
raw_affiliation_strings: Solid Tumour Program, Precision Cancer Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
raw_author_name: Lisa M. Butler
raw_affiliation_strings: South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
raw_author_name: George Church
raw_affiliation_strings: Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA
Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, MA, USA
raw_author_name: Alexander Swarbrick
raw_affiliation_strings: Cancer Ecosystems Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia
School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales Sydney, Sydney, New South Wales, Australia
raw_author_name: Christopher E. Mason
raw_affiliation_strings: Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, USA. chm2042@med.cornell.edu
The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA. chm2042@med.cornell.edu
Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY, USA
raw_author_name: Luciano G. Martelotto
raw_affiliation_strings: Adelaide Centre for Epigenetics, Adelaide, South Australia, Australia. lucianomartelotto@gmail.com
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia. lucianomartelotto@gmail.com
The University of Adelaide, Adelaide, South Australia, Australia. lucianomartelotto@gmail.com
Adelaide Centre for Epigenetics, Adelaide, South Australia, Australia
South Australian immunoGENomics Cancer Institute, Adelaide, South Australia, Australia
The University of Adelaide, Adelaide, South Australia, Australia