Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction
Year: 2025
Type: article
Language: en
Topic: Genetic Associations and Epidemiology
Authors and affiliations:
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Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA
raw_author_name: Ta-Yu Yang
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McGill University Health Centre and Research Institute, Montréal, Quebec, Canada
McGill University, Montréal, Quebec, Canada
raw_author_name: Shinsuke Itoh
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Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
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Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval, Quebec City, Quebec, Canada
raw_author_name: Line Dufresne
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raw_author_name: Issei Komuro
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International University of Health and Welfare, Tokyo, Japan
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Duke Molecular Physiology Institute, Duke University, Durham, NC, USA
raw_author_name: Megan E. Ramaker
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raw_author_name: Fabien Laporte
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Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
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Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
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raw_author_name: Sisse R. Ostrowski
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Harvard-MIT Health Sciences and Technology Program, Harvard Medical School, Boston, MA, USA
Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, USA
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Institute for Molecular Medicine Finland, HiLIFE, University of Helsinki, Helsinki, Finland
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raw_author_name: Sarah Finer
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raw_author_name: Johannes Schumacher
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Institute of Human Genetics, University of Bonn and University Hospital Bonn, Bonn, Germany
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raw_author_name: Baravan Al-Kassou
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Department of Cardiology, German Heart Centre Munich, TUM University Hospital, School of Medicine and Health, Technical University of Munich, Munich, Germany
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Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
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NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK
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NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK
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NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK
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NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, UK
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