Lentinan inhibits colorectal cancer stemness by binding CD133 and suppressing the CD133/p85/p-AKT signaling axis
Year: 2025
Type: article
Language: en
Topic: Polysaccharides and Plant Cell Walls
Authors and affiliations:
raw_author_name: Yan Liu
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
raw_author_name: Lufei Yang
raw_affiliation_strings: Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Junxi Liu
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
raw_author_name: Zihao He
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
raw_author_name: Jingyi Wang
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, China
raw_author_name: Jingyi Wang
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, China
raw_author_name: Yu Zhang
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Kaiping Wang
raw_affiliation_strings: Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
raw_author_name: Jinglin Wang
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, China
raw_author_name: Jinglin Wang
raw_affiliation_strings: Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Natural Active Polysaccharides, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Hubei Key Laboratory of Nature Medicinal Chemistry and Resource Evaluation, Tongji Medical College of Pharmacy, Huazhong University of Science and Technology, Wuhan, China
Hubei Province Clinical Research Center for Precision Medicine for Critical Illness, Wuhan, China
State Key Laboratory of Neurology and Oncology Drug Development, Nanjing, China