Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes
Year: 2025
Type: article
Language: en
Topic: DNA Repair Mechanisms
Authors and affiliations:
raw_author_name: Ksenia Krupina
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Alexander Goginashvili
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Michael W. Baughn
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Stephen Moore
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Christopher D. Steele
raw_affiliation_strings: Department of Bioengineering, University of California at San Diego, La Jolla, USA
Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
Moores Cancer Center, University of California at San Diego, La Jolla, USA
raw_author_name: Amy T. Nguyen
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Daniel L. Zhang
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Jonas Koeppel
raw_affiliation_strings: Department of Haematology, University of Cambridge, Cambridge, UK
Wellcome Trust Sanger Center, Hinxton, UK
raw_author_name: Prasad Trivedi
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Aarti Malhotra
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: David Jenkins
raw_affiliation_strings: Department of Cell and Developmental Biology, University of California at San Diego, La Jolla, USA
raw_author_name: Andrew K. Shiau
raw_affiliation_strings: Department of Cell and Developmental Biology, University of California at San Diego, La Jolla, USA
raw_author_name: Yohei Miyake
raw_affiliation_strings: Sanford Stem Cell Institute, University of California San Diego, La Jolla, USA
raw_author_name: Tomoyuki Koga
raw_affiliation_strings: Department of Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Shunichiro Miki
raw_affiliation_strings: Department of Medicine, University of California at San Diego, La Jolla, USA
raw_author_name: Frank B. Furnari
raw_affiliation_strings: Department of Medicine, University of California at San Diego, La Jolla, USA
Sanford Stem Cell Institute, University of California San Diego, La Jolla, USA
raw_author_name: Peter J. Campbell
raw_affiliation_strings: Department of Haematology, University of Cambridge, Cambridge, UK
Wellcome Trust Sanger Center, Hinxton, UK
raw_author_name: Ludmil B. Alexandrov
raw_affiliation_strings: Department of Bioengineering, University of California at San Diego, La Jolla, USA
Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
Moores Cancer Center, University of California at San Diego, La Jolla, USA
Sanford Stem Cell Institute, University of California San Diego, La Jolla, USA
raw_author_name: Don W. Cleveland
raw_affiliation_strings: Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, USA
Moores Cancer Center, University of California at San Diego, La Jolla, USA