Targeted inhibition of mu-opioid receptors in neuronal subpopulations by membrane-tethered Naloxo-DART antagonists
Year: 2025
Type: article
Language: en
Topic: Receptor Mechanisms and Signaling
Authors and affiliations:
raw_author_name: J. Sanchez
raw_affiliation_strings: Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Nottingham, UK
raw_author_name: A. Bonifazi
raw_affiliation_strings: Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA
raw_author_name: S. Groom
raw_affiliation_strings: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
raw_author_name: M.O. Sambrook
raw_affiliation_strings: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
raw_author_name: G.A. Camacho-Hernandez
raw_affiliation_strings: Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA
raw_author_name: E.J. Kuijer
raw_affiliation_strings: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
raw_author_name: S. Karimi
raw_affiliation_strings: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
raw_author_name: K.U. Therese
raw_affiliation_strings: Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA
raw_author_name: M. Hauge Pedersen
raw_affiliation_strings: Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA
raw_author_name: C. Rauffenbart
raw_affiliation_strings: Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA
raw_author_name: M. Canals
raw_affiliation_strings: Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Nottingham, UK
raw_author_name: A.H. Newman
raw_affiliation_strings: Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, MD 21224, USA. Electronic address: anewman@intra.nida.nih.gov
raw_author_name: C.P. Bailey
raw_affiliation_strings: Department of Pharmacy and Pharmacology, University of Bath, Bath, UK. Electronic address: cb304@bath.ac.uk
raw_author_name: J.A. Javitch
raw_affiliation_strings: Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address: jonathan.javitch@nyspi.columbia.edu
raw_author_name: J.R. Lane
raw_affiliation_strings: Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK; Centre of Membrane Proteins and Receptors, University of Birmingham and University of Nottingham, Nottingham, UK. Electronic address: rob.lane@nottingham.ac.uk