Sacubitril-Valsartan for the Prevention of Anthracycline Cardiotoxicity in Patients With Elevated Cardiac Troponin I Concentration During Chemotherapy: A Double-Blind Randomized Placebo-Controlled Clinical Trial: The SARAH Trial
Year: 2025
Type: article
Language: en
Topic: Chemotherapy-induced cardiotoxicity and mitigation
Authors and affiliations:
raw_author_name: Marcely Gimenes Bonatto
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
Department of Cardiology, Division of Heart Failure, Santa Casa of Curitiba Hospital, Paraná, Brazil (M.G.B., A.d.O.C.)
Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Mônica Samuel Avila
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Sílvia Moreira Ayub Ferreira
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Luka David Lechinewski
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Rafael de Almeida Torres
raw_affiliation_strings: Department of Cardiovascular Imaging, Institute of Neurology of Curitiba Hospital, Paraná, Brazil (R.d.A.T., A.d.N.C.)
raw_author_name: Amanda de Nadai Costa
raw_affiliation_strings: Department of Cardiovascular Imaging, Institute of Neurology of Curitiba Hospital, Paraná, Brazil (R.d.A.T., A.d.N.C.)
raw_author_name: Nadya Rocumback Alves da Costa
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Andressa de Oliveira Coiradas
raw_affiliation_strings: Department of Cardiology, Division of Heart Failure, Santa Casa of Curitiba Hospital, Paraná, Brazil (M.G.B., A.d.O.C.)
raw_author_name: Talita Beithum Ribeiro Mialski
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Julyana Maiolino
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Tammy Tiemy Ota
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Laís Contin
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Larissa Arlete Mosko
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Marcio Sommer Bittencourt
raw_affiliation_strings: Department of Medicine, Division of Cardiology, University of Pittsburgh, PA (M.S.B.)
raw_author_name: Sanderson Cauduro
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Lídia Ana Zytynski Moura
raw_affiliation_strings: Department of Medicine, Division of Cardiology, Pontifical Catholic University of Paraná, Curitiba, Paraná, Brazil (L.A.Z.M.)
raw_author_name: Edimar Alcides Bocchi
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Amanda de Nadai Costa
raw_affiliation_strings: Department of Cardiovascular Imaging, Institute of Neurology of Curitiba Hospital, Paraná, Brazil (R.d.A.T., A.d.N.C.)
raw_author_name: Andressa de Oliveira Coiradas
raw_affiliation_strings: Department of Cardiology, Division of Heart Failure, Santa Casa of Curitiba Hospital, Paraná, Brazil (M.G.B., A.d.O.C.)
raw_author_name: Edimar Alcides Bocchi
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Julyana Maiolino
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Laís Contin
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Larissa Arlete Mosko
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Lídia Ana Zytynski Moura
raw_affiliation_strings: Department of Medicine, Division of Cardiology, Pontifical Catholic University of Paraná, Curitiba, Paraná, Brazil (L.A.Z.M.)
raw_author_name: Luka David Leichinewski
raw_author_name: Marcely Gimenes Bonatto
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
Department of Cardiology, Division of Heart Failure, Santa Casa of Curitiba Hospital, Paraná, Brazil (M.G.B., A.d.O.C.)
Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Marcio Sommer Bittencourt
raw_affiliation_strings: Department of Medicine, Division of Cardiology, University of Pittsburgh, PA (M.S.B.)
raw_author_name: Mônica Samuel Avila
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Nadya Rocumback Alves da Costa
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Rafael de Almeida Torres
raw_affiliation_strings: Department of Cardiovascular Imaging, Institute of Neurology of Curitiba Hospital, Paraná, Brazil (R.d.A.T., A.d.N.C.)
raw_author_name: Sanderson Cauduro
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Sílvia Moreira Ayub Ferreira
raw_affiliation_strings: Heart Failure Clinics, Instituto do Coração (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil (M.G.B., M.S.A., S.M.A.F., E.A.B.)
raw_author_name: Talita Beithum Ribeiro Mialski
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)
raw_author_name: Tammy Tiemy Ota
raw_affiliation_strings: Department of Cardiology, Division of Cardio-Oncology, Erasto Gaertner Hospital, Curitiba, Paraná, Brazil (M.G.B., L.D.L., N.R.A.d.C., T.B.R.M., J.M., T.T.O., L.C., L.A.M., S.C.)