Azetidin-2-ones: structures of antimitotic compounds based on the 1-(3,4,5-trimethoxyphenyl)azetidin-2-one core
Twamley, Brendan; O'Boyle, Niamh M.; Meegan, Mary J.; Acta Crystallographica Section E 76 (2020) 1187–1194; doi:10.1107/S2056989020008555

data_2243461
_publ_section_title
;
 Azetidin-2-ones: structures of antimitotic compounds based on the
 1-(3,4,5-trimethoxyphenyl)azetidin-2-one core
;
_journal_coeditor_code           ZL2789
_journal_issue                   8
_journal_name_full               'Acta Crystallographica Section E'
_journal_page_first              1187
_journal_page_last               1194
_journal_paper_doi               10.1107/S2056989020008555
_journal_volume                  76
_journal_year                    2020
_chemical_formula_iupac          'C25 H24 F N O5'
_chemical_formula_moiety         'C25 H24 F N O5'
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_chemical_name_systematic
3-(4-Fluorophenyl)-4-(4-methoxyphenyl)-1-(3,4,5-trimethoxyphenyl)azetidin-2-one
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_space_group_name_Hall           '-P 2ac 2ab'
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Olex2 1.2
(compiled 2018.05.29 svn.r3508 for OlexSys, GUI svn.r5506)
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SAINT (Bruker, 2016)
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APEX3 (Bruker, 2017)
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SAINT  (Bruker, 2016)
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<i>OLEX2</i> (Dolomanov <i>et al.</i>,  2009)
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<i>OLEX2</i> (Dolomanov <i>et al.</i>,  2009)
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SHELXL (Sheldrick, 2015b)
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SHELXT (Sheldrick, 2015a)
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;
(SADABS; Bruker, 2016)
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'w=1/[\s^2^(Fo^2^)+(0.0465P)^2^+1.1677P] where P=(Fo^2^+2Fc^2^)/3'
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