Insertion of SnCl₂ into the Pd–Cl Bond: Mechanistic Elucidation and Antitumor Evaluation of Trichlorostannyl Palladium-NHC Allyl Complexes in Ovarian Cancer Models
Botter, Eleonora; Lauteri, Valentina; Rubbi, Alessandro; Orian, Laura; Forner, Matteo; Gandin, Valentina; Demitri, Nicola; Canzonieri, Vincenzo; Rizzolio, Flavio; Cavarzerani, Enrico; Visentin, Fabiano; Scattolin, Thomas; Dalton Transactions  (2026) –; doi:10.1039/D6DT00680A

data_7720751
_publ_section_title
;
 Insertion of SnCl<sub>2</sub> into the Pd-Cl bond: mechanistic
 elucidation and antitumor evaluation of trichlorostannyl palladium-NHC
 allyl complexes in ovarian cancer models.
;
_journal_issue                   16
_journal_name_full
'Dalton transactions (Cambridge, England : 2003)'
_journal_page_first              6351
_journal_page_last               6372
_journal_paper_doi               10.1039/d6dt00680a
_journal_volume                  55
_journal_year                    2026
_chemical_formula_moiety         'C25 H31 Cl3 N2 Pd Sn'
_chemical_formula_sum            'C25 H31 Cl3 N2 Pd Sn'
_chemical_formula_weight         690.96
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_space_group_name_Hall           '-P 2ybc'
_space_group_name_H-M_alt        'P 1 21/c 1'
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_atom_sites_solution_secondary   difmap
_audit_creation_method           SHELXL-2019/3
_audit_update_record
;
2025-12-01 deposited with the CCDC.	2026-03-25 downloaded from the CCDC.
;
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_cell_measurement_temperature    100(2)
_cell_measurement_theta_max      31.104
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_cell_volume                     2759.6(10)
_computing_cell_refinement       'XDS (Kabsch, 2010)'
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_computing_molecular_graphics    'Ortep3 for Windows - Coot'
_computing_publication_material  'enCIFer - publCIF'
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_computing_structure_solution    'SHELXT (Sheldrick, 2015)'
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_diffrn_measured_fraction_theta_max 0.898
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;
'Arinax MD2s Goniometer, Pilatus 6M detector'
;
_diffrn_measurement_method       'Rotating crystal'
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_diffrn_reflns_Laue_measured_fraction_max 0.898
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_diffrn_reflns_limit_l_min       -34
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_diffrn_source                   'Elettra Synchrotron - XRD2 BL'
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_exptl_crystal_description       'Thin blocks'
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_refine_ls_structure_factor_coef Fsqd
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'w=1/[\s^2^(Fo^2^)+(0.0233P)^2^+1.9018P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_reflns_number_gt                11616
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_reflns_threshold_expression     'I > 2\s(I)'
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_cod_depositor_comments
'Adding full bibliography for 7720746--7720751.cif.'
_cod_original_sg_symbol_H-M      'P 21/c'
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_shelx_res_checksum              43937