Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents.
Maguire, Casey J.; Chen, Zhi; Mocharla, Vani P.; Sriram, Madhavi; Strecker, Tracy E.; Hamel, Ernest; Zhou, Heling; Lopez, Ramona; Wang, Yifan; Mason, Ralph P.; Chaplin, David J.; Trawick, Mary Lynn; Pinney, Kevin G.; MedChemComm 9 (2018) 1649–1662; doi:10.1039/c8md00322j

data_7122245
_publ_section_title
;
 Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4
 and their biological evaluation as anticancer agents.
;
_journal_issue                   10
_journal_name_full               MedChemComm
_journal_page_first              1649
_journal_page_last               1662
_journal_paper_doi               10.1039/c8md00322j
_journal_volume                  9
_journal_year                    2018
_chemical_formula_sum            'C21 H22 O6'
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_space_group_crystal_system      monoclinic
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_space_group_name_Hall           '-C 2yc'
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_symmetry_space_group_name_Hall  '-C 2yc'
_symmetry_space_group_name_H-M   'C 1 2/c 1'
_atom_sites_solution_hydrogens   mixed
_audit_creation_method           SHELXL-2013
_audit_update_record
;
2018-05-10 deposited with the CCDC.
2018-08-14 downloaded from the CCDC.
;
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_diffrn_ambient_temperature      150(2)
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_refine_ls_shift/su_mean         0.000
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'w=1/[\s^2^(Fo^2^)+(0.0490P)^2^+1.6968P] where P=(Fo^2^+2Fc^2^)/3'
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_reflns_threshold_expression     'I > 2\s(I)'
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_cod_depositor_comments
'Adding full bibliography for 7122245--7122246.cif.'
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