Tandem Prins cyclization for the synthesis of indole fused spiro-1,4-diazocane scaffolds.
Rapelli, Chandrashekhar; Sridhar, Balasubramanian; Subba Reddy, B. V.; Organic & biomolecular chemistry 18 (2020) 6710–6715; doi:10.1039/d0ob01384f

data_7157672
_publ_section_title
;
 Tandem Prins cyclization for the synthesis of indole fused
 spiro-1,4-diazocane scaffolds.
;
_journal_issue                   34
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              6710
_journal_page_last               6715
_journal_paper_doi               10.1039/d0ob01384f
_journal_volume                  18
_journal_year                    2020
_chemical_formula_moiety         'C34 H31 Br N2 O3 S, C H Cl3'
_chemical_formula_sum            'C35 H32 Br Cl3 N2 O3 S'
_chemical_formula_weight         746.94
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_space_group_name_Hall           '-P 1'
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_atom_sites_solution_hydrogens   geom
_audit_creation_method           SHELXL-2018/3
_audit_update_record
;
2020-03-11 deposited with the CCDC.	2020-08-17 downloaded from the CCDC.
;
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_computing_structure_solution    '<i>SHELXT</i> (Sheldrick, 2015a)'
_diffrn_ambient_temperature      294(2)
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_diffrn_measurement_device_type  'Bruker D8 QUEST PHOTON-100'
_diffrn_measurement_method       '\w and \f'
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_refine_ls_restrained_S_all      1.086
_refine_ls_R_factor_all          0.1317
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_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0747P)^2^+10.8493P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.2284
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_reflns_number_gt                4063
_reflns_number_total             5950
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d0ob01384f2.cif
_cod_data_source_block           KA849_0m
_cod_depositor_comments          'Adding full bibliography for 7157672.cif.'
_cod_database_code               7157672
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