Controlling chirality in the synthesis of 4 + 4 diastereomeric amine macrocycles derived from <i>trans</i>-1,2-diaminocyclopentane and 2,6-diformylpyridine.
Fedorowicz, Dominika; Banach, Sylwia; Koza, Patrycja; Frydrych, Rafał; Ślepokura, Katarzyna; Gregoliński, Janusz; Organic & biomolecular chemistry 20 (2022) 1080–1094; doi:10.1039/d1ob02410h

data_7158470
_publ_section_title
;
 Controlling chirality in the synthesis of 4 + 4 diastereomeric amine
 macrocycles derived from <i>trans</i>-1,2-diaminocyclopentane and
 2,6-diformylpyridine.
;
_journal_issue                   5
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              1080
_journal_page_last               1094
_journal_paper_doi               10.1039/d1ob02410h
_journal_volume                  20
_journal_year                    2022
_chemical_formula_moiety         'C48 H76 N12, 8(Cl), 3(C H4 O), H2 O'
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;
2021-07-22 deposited with the CCDC.	2021-12-23 downloaded from the CCDC.
;
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_exptl_absorpt_process_details
;
CrysAlisPro 1.171.41.80a (Rigaku Oxford Diffraction, 2020)
Empirical absorption correction using spherical harmonics,
implemented in SCALE3 ABSPACK scaling algorithm.
;
_exptl_crystal_colour            colourless
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_exptl_crystal_description       plate
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_exptl_crystal_size_mid          0.31
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0780P)^2^] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_refine_ls_wR_factor_ref         0.1536
_reflns_Friedel_coverage         0.000
_reflns_number_gt                8839
_reflns_number_total             11983
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d1ob02410h2.cif
_cod_data_source_block           3_l16hc
_cod_depositor_comments
'Adding full bibliography for 7158467--7158470.cif.'
_cod_database_code               7158470
_shelx_shelxl_version_number     2014/7
_shelx_estimated_absorpt_t_min   0.857
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