From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3).
Lassagne, Frédéric; Duguépéroux, Camille; Roca, Carlos; Perez, Concepcion; Martinez, Ana; Baratte, Blandine; Robert, Thomas; Ruchaud, Sandrine; Bach, Stéphane; Erb, William; Roisnel, Thierry; Mongin, Florence; Organic & biomolecular chemistry 18 (2019) 154–162; doi:10.1039/c9ob02002k

data_7157233
_publ_section_title
;
 From simple quinoxalines to potent oxazolo[5,4-f]quinoxaline inhibitors
 of glycogen-synthase kinase 3 (GSK3).
;
_journal_issue                   1
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              154
_journal_page_last               162
_journal_paper_doi               10.1039/c9ob02002k
_journal_volume                  18
_journal_year                    2019
_chemical_compound_source        'synthesis as described'
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_audit_update_record
;
2019-11-11 deposited with the CCDC.	2019-11-27 downloaded from the CCDC.
;
_cell_angle_alpha                90
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'SXGRAPH (L. Farrugia, 1999), Mercury (CSD, 2016)'
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_diffrn_radiation_monochromator  'multilayer monochromator'
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;
  [Sheldrick, G.M. (2014). SADABS Bruker AXS Inc., Madison, Wisconsin, USA]
;
_exptl_crystal_colour            colourless
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_exptl_crystal_size_mid          0.250
_exptl_crystal_size_min          0.090
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0442P)^2^+1.0595P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_refine_ls_wR_factor_ref         0.1021
_reflns_Friedel_coverage         0.000
_reflns_number_gt                3215
_reflns_number_total             3900
_reflns_threshold_expression     >2sigma(I)
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_cod_data_source_block           FL316
_cod_depositor_comments
'Adding full bibliography for 7157232--7157233.cif.'
_cod_original_sg_symbol_H-M      'P 21/n'
_cod_database_code               7157233
_shelx_res_checksum              47294