Visible-light-induced C(sp<sup>3</sup>)-H functionalizations of piperidines to 3,3-dichloro-2-hydroxy-piperidines with N-chlorosuccinimide.
Wang, Fang; Liu, Xiaoli; Wang, Lei; Organic & biomolecular chemistry 19 (2021) 6141–6146; doi:10.1039/d1ob00868d

data_7158130
_publ_section_title
;
 Visible-light-induced C(sp<sup>3</sup>)-H functionalizations of
 piperidines to 3,3-dichloro-2-hydroxy-piperidines with
 N-chlorosuccinimide.
;
_journal_issue                   27
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              6141
_journal_page_last               6146
_journal_paper_doi               10.1039/d1ob00868d
_journal_volume                  19
_journal_year                    2021
_chemical_formula_sum            'C17 H17 Cl2 N O'
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_atom_sites_solution_hydrogens   geom
_audit_creation_method           SHELXL-2014/7
_audit_update_record
;
2021-04-30 deposited with the CCDC.	2021-06-16 downloaded from the CCDC.
;
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_diffrn_measured_fraction_theta_max 0.999
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_diffrn_radiation_type           MoK\a
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_diffrn_reflns_Laue_measured_fraction_full 0.999
_diffrn_reflns_Laue_measured_fraction_max 0.999
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_refine_ls_abs_structure_details
;
 Flack x determined using 1055 quotients [(I+)-(I-)]/[(I+)+(I-)] 
 (Parsons, Flack and Wagner, Acta Cryst. B69 (2013) 249-259). 
;
_refine_ls_abs_structure_Flack   0.03(3)
_refine_ls_extinction_method     none
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0577P)^2^+0.3584P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.0816
_refine_ls_wR_factor_ref         0.0871
_reflns_Friedel_coverage         0.980
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_reflns_Friedel_fraction_max     0.991
_reflns_number_gt                2439
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_cod_depositor_comments          'Adding full bibliography for 7158130.cif.'
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_shelx_estimated_absorpt_t_min   0.903
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