Stereoselective synthesis of dispiro heterocycles by [3 + 2] cycloaddition of azomethine ylides with a thiazolo[3,2-<i>a</i>]indole derivative.
Sathi, Vidya; Thomas, Noble V.; Deepthi, Ani; Organic & biomolecular chemistry 18 (2020) 7822–7826; doi:10.1039/d0ob01559h

data_7157705
_publ_section_title
;
 Stereoselective synthesis of dispiro heterocycles by [3 + 2]
 cycloaddition of azomethine ylides with a thiazolo[3,2-<i>a</i>]indole
 derivative.
;
_journal_issue                   39
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              7822
_journal_page_last               7826
_journal_paper_doi               10.1039/d0ob01559h
_journal_volume                  18
_journal_year                    2020
_chemical_formula_moiety         'C27 H20 N2 O8 S'
_chemical_formula_sum            'C27 H20 N2 O8 S'
_chemical_formula_weight         532.51
_space_group_crystal_system      triclinic
_space_group_IT_number           2
_space_group_name_Hall           '-P 1'
_space_group_name_H-M_alt        'P -1'
_atom_sites_solution_hydrogens   geom
_audit_creation_method           SHELXL-2018/3
_audit_update_record
;
2020-07-24 deposited with the CCDC.	2020-09-15 downloaded from the CCDC.
;
_cell_angle_alpha                70.281(6)
_cell_angle_beta                 78.966(5)
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_cell_measurement_temperature    296(2)
_cell_measurement_theta_max      24.54
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_computing_cell_refinement       'APEX3/SAINT (Bruker, 2016)'
_computing_data_collection       'APEX3 (Bruker, 2016)'
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_computing_molecular_graphics    'ORTEP3- 2014.1(Farrugia, 1997) '
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_diffrn_ambient_temperature      296(2)
_diffrn_detector_area_resol_mean 0
_diffrn_measured_fraction_theta_full 1.000
_diffrn_measured_fraction_theta_max 1.000
_diffrn_measurement_device_type  'Bruker KAPPA APEX-II CCD'
_diffrn_measurement_method       '\f and \w scans'
_diffrn_radiation_type           MoK\a
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_diffrn_reflns_av_R_equivalents  0.0571
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_diffrn_reflns_point_group_measured_fraction_full 1.000
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_diffrn_reflns_theta_max         25.000
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_diffrn_source                   'sealed tube'
_exptl_absorpt_coefficient_mu    0.189
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_exptl_absorpt_correction_T_min  0.968
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details   'SADABS (Bruker, 2016)'
_exptl_crystal_colour            yellow
_exptl_crystal_density_diffrn    1.448
_exptl_crystal_density_meas      1.447
_exptl_crystal_density_method    none
_exptl_crystal_description       block
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_exptl_crystal_size_mid          0.085
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_refine_diff_density_max         0.214
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_refine_diff_density_rms         0.042
_refine_ls_extinction_method     none
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_refine_ls_hydrogen_treatment    constr
_refine_ls_matrix_type           full
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_refine_ls_number_reflns         4293
_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      1.009
_refine_ls_R_factor_all          0.0653
_refine_ls_R_factor_gt           0.0416
_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0474P)^2^+0.4940P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.0945
_refine_ls_wR_factor_ref         0.1107
_reflns_Friedel_coverage         0.000
_reflns_number_gt                3177
_reflns_number_total             4293
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d0ob01559h2.cif
_cod_data_source_block           shelx
_cod_depositor_comments          'Adding full bibliography for 7157705.cif.'
_cod_database_code               7157705
_shelx_shelxl_version_number     2018/3
_shelx_estimated_absorpt_t_min   0.968
_shelx_estimated_absorpt_t_max   0.990
_shelx_res_checksum              57835
_shelx_hkl_checksum              43521