One pot synthesis of nitrogen-containing polycyclic δ-lactones by double nucleophilic addition of bis(trimethylsilyl)ketene acetals to pyridinesAll new compounds described in this paper were fully characterized by 200 and 400 MHz 1H NMR, 50 or 100 MHz 13C NMR, mass spectrometry and/or elemental analyses.
Rudler, Henri; Denise, Bernard; Parlier, Andrée; Daran, Jean-Claude; Chemical Communications  (2002) 940–; doi:10.1039/b201780f

data_7111206
_publ_section_title
;
 One pot synthesis of nitrogen-containing polycyclic \d-lactones by double
 nucleophilic addition of bis(trimethylsilyl)ketene acetals to
 pyridinesAll new compounds described in this paper were fully
 characterized by 200 and 400 MHz 1H NMR, 50 or 100 MHz 13C NMR, mass
 spectrometry and/or elemental analyses.
;
_journal_issue                   9
_journal_name_full               'Chemical Communications'
_journal_page_first              940
_journal_paper_doi               10.1039/b201780f
_journal_year                    2002
_chemical_compound_source        'synthesis as described'
_chemical_formula_moiety         'C15 H14 I1 N1 O4'
_chemical_formula_structural     'C15 H14 I1 N1 O4'
_chemical_formula_sum            'C15 H14 I N O4'
_chemical_formula_weight         399.17
_space_group_IT_number           14
_symmetry_cell_setting           monoclinic
_symmetry_Int_Tables_number      14
_symmetry_space_group_name_Hall  '-P 2yn'
_symmetry_space_group_name_H-M   'P 1 21/n 1'
_atom_sites_solution_hydrogens   geom
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   difmap
_audit_creation_method           SHELXL-97
_cell_angle_alpha                90.00
_cell_angle_beta                 92.967(6)
_cell_angle_gamma                90.00
_cell_formula_units_Z            4
_cell_length_a                   6.1448(5)
_cell_length_b                   12.5047(12)
_cell_length_c                   18.9654(14)
_cell_measurement_reflns_used    10000
_cell_measurement_temperature    180(2)
_cell_measurement_theta_max      25.02
_cell_measurement_theta_min      3.43
_cell_volume                     1455.3(2)
_computing_cell_refinement       'CRYSALISRED 169,Oxford-Diffraction, 2001'
_computing_data_collection       'CRYSALIS 169, Oxford-Diffraction, 2001'
_computing_data_reduction        'CRYSALISRED 169,Oxford-Diffraction, 2001'
_computing_molecular_graphics    'Ortep-3 for Windows(Farrugia,1997)'
_computing_publication_material  'WinGX (Farrugia, 1999)'
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 1997)'
_computing_structure_solution    'SHELXS-97 (Sheldrick, 1997)'
_diffrn_ambient_temperature      180(2)
_diffrn_measured_fraction_theta_full 0.976
_diffrn_measured_fraction_theta_max 0.976
_diffrn_measurement_device_type  'Oxford-Diffraction Xcalibur'
_diffrn_measurement_method       '\w,\f scans'
_diffrn_radiation_monochromator  graphite
_diffrn_radiation_source         'fine-focus sealed tube'
_diffrn_radiation_type           MoK\a
_diffrn_radiation_wavelength     0.71073
_diffrn_reflns_av_R_equivalents  0.0889
_diffrn_reflns_av_sigmaI/netI    0.0692
_diffrn_reflns_limit_h_max       6
_diffrn_reflns_limit_h_min       -7
_diffrn_reflns_limit_k_max       14
_diffrn_reflns_limit_k_min       -14
_diffrn_reflns_limit_l_max       22
_diffrn_reflns_limit_l_min       -22
_diffrn_reflns_number            7143
_diffrn_reflns_theta_full        25.02
_diffrn_reflns_theta_max         25.02
_diffrn_reflns_theta_min         3.43
_diffrn_standards_decay_%        none
_diffrn_standards_interval_count 0
_diffrn_standards_interval_time  0
_diffrn_standards_number         0
_exptl_absorpt_coefficient_mu    2.216
_exptl_absorpt_correction_T_max  0.6860
_exptl_absorpt_correction_T_min  0.5938
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details
;
[c.f. r.h. blessing, acta cryst. (1995), a51, 33-38]
;
_exptl_crystal_colour            colourless
_exptl_crystal_density_diffrn    1.822
_exptl_crystal_density_meas      ?
_exptl_crystal_density_method    'not measured'
_exptl_crystal_description       prism
_exptl_crystal_F_000             784
_exptl_crystal_size_max          0.16
_exptl_crystal_size_mid          0.06
_exptl_crystal_size_min          0.03
_refine_diff_density_max         1.716
_refine_diff_density_min         -1.313
_refine_diff_density_rms         0.203
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   1.123
_refine_ls_hydrogen_treatment    mixed
_refine_ls_matrix_type           full
_refine_ls_number_parameters     191
_refine_ls_number_reflns         2514
_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      1.123
_refine_ls_R_factor_all          0.0799
_refine_ls_R_factor_gt           0.0660
_refine_ls_shift/su_max          0.006
_refine_ls_shift/su_mean         0.001
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'calc w=1/[\s^2^(Fo^2^)+(0.0901P)^2^+4.4481P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1593
_refine_ls_wR_factor_ref         0.1686
_reflns_number_gt                2116
_reflns_number_total             2514
_reflns_threshold_expression     >2\s(I)
_cod_data_source_file            b201780fsup1.cif
_cod_data_source_block           hrdat
_cod_depositor_comments
;
The following automatic conversions were performed:

'_exptl_crystal_density_meas' value 'not measured' was changed to '?'
- the value is perceived as not measured.

Automatic conversion script
Id: cif_fix_values 3008 2015-01-20 13:52:24Z robertas 
;
_cod_original_formula_sum        'C15 H14 I1 N1 O4'
_cod_database_code               7111206