Mono-carboxylated diaminedichloridoplatinum(iv) complexes - selective synthesis, characterization, and cytotoxicity.
Pichler, Verena; Valiahdi, Seied M.; Jakupec, Michael A.; Arion, Vladimir B.; Galanski, Markus; Keppler, Bernhard K.; Dalton transactions (Cambridge, England : 2003) 40 (2011) 8187–8192; doi:10.1039/c1dt10301f

data_7016355
_publ_section_title
;
 Mono-carboxylated diaminedichloridoplatinum(iv) complexes - selective
 synthesis, characterization, and cytotoxicity.
;
_journal_issue                   32
_journal_name_full
'Dalton transactions (Cambridge, England : 2003)'
_journal_page_first              8187
_journal_page_last               8192
_journal_paper_doi               10.1039/c1dt10301f
_journal_volume                  40
_journal_year                    2011
_chemical_formula_moiety         'C4 H14 Cl2 N2 O2 Pt'
_chemical_formula_sum            'C4 H14 Cl2 N2 O2 Pt'
_chemical_formula_weight         388.16
_chemical_name_common
;(OC-6-43)-Dichlorido(N,N-dimethyl-ethane-1,2-diamine)dihydro-
xidoplatinum(IV)
;
_chemical_name_systematic
;
(OC-6-43)-Dichlorido(N,N-dimethyl-ethane-1,2-diamine)dihydro-
xidoplatinum(IV)
;
_space_group_IT_number           88
_symmetry_cell_setting           tetragonal
_symmetry_space_group_name_Hall  '-I 4ad'
_symmetry_space_group_name_H-M   'I 41/a :2'
_atom_sites_solution_hydrogens   geom
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   difmap
_audit_creation_method           SHELXL-97
_cell_angle_alpha                90.00
_cell_angle_beta                 90.00
_cell_angle_gamma                90.00
_cell_formula_units_Z            16
_cell_length_a                   23.064(5)
_cell_length_b                   23.064(5)
_cell_length_c                   7.5597(16)
_cell_measurement_reflns_used    6837
_cell_measurement_temperature    296(2)
_cell_measurement_theta_max      24.92
_cell_measurement_theta_min      2.49
_cell_volume                     4021.4(15)
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 1997)'
_computing_structure_solution    'SHELXS-97 (Sheldrick, 1990)'
_diffrn_ambient_temperature      296(2)
_diffrn_measured_fraction_theta_full 0.987
_diffrn_measured_fraction_theta_max 0.987
_diffrn_radiation_monochromator  graphite
_diffrn_radiation_source         'fine-focus sealed tube'
_diffrn_radiation_type           MoK\a
_diffrn_radiation_wavelength     0.71073
_diffrn_reflns_av_R_equivalents  0.3116
_diffrn_reflns_av_sigmaI/netI    0.1274
_diffrn_reflns_limit_h_max       27
_diffrn_reflns_limit_h_min       -27
_diffrn_reflns_limit_k_max       27
_diffrn_reflns_limit_k_min       -27
_diffrn_reflns_limit_l_max       9
_diffrn_reflns_limit_l_min       -8
_diffrn_reflns_number            26869
_diffrn_reflns_theta_full        25.33
_diffrn_reflns_theta_max         25.33
_diffrn_reflns_theta_min         2.84
_exptl_absorpt_coefficient_mu    14.449
_exptl_absorpt_correction_T_max  0.5319
_exptl_absorpt_correction_T_min  0.2205
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details   SADABS
_exptl_crystal_colour            yellow
_exptl_crystal_density_diffrn    2.565
_exptl_crystal_density_method    'not measured'
_exptl_crystal_description       stick
_exptl_crystal_F_000             2880
_exptl_crystal_size_max          0.15
_exptl_crystal_size_mid          0.05
_exptl_crystal_size_min          0.05
_refine_diff_density_max         2.546
_refine_diff_density_min         -1.912
_refine_diff_density_rms         0.430
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   1.059
_refine_ls_hydrogen_treatment    constr
_refine_ls_matrix_type           full
_refine_ls_number_parameters     100
_refine_ls_number_reflns         1805
_refine_ls_number_restraints     1
_refine_ls_restrained_S_all      1.059
_refine_ls_R_factor_all          0.1099
_refine_ls_R_factor_gt           0.0643
_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'calc w=1/[\s^2^(Fo^2^)+(0.0467P)^2^+322.2174P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1463
_refine_ls_wR_factor_ref         0.1766
_reflns_number_gt                1228
_reflns_number_total             1805
_reflns_threshold_expression     >2sigma(I)
_cod_data_source_file            c1dt10301f.txt
_cod_data_source_block           MADI008
_cod_original_sg_symbol_H-M      I41/a
_cod_database_code               7016355