Structural and physicochemical characterization of sulfonylhydrazone derivatives designed as hypoglycemic agents
Ibiapino, Amanda Laura; de Figueiredo, Laysa Pires; Lima, Lídia Moreira; Barreiro, Eliezer J.; Punzo, Francesco; Ferreira, Fabio Furlan; New J. Chem. 41 (2017) 6464–6474; doi:10.1039/C7NJ00074J

data_7056253
_publ_section_title
;
 Structural and physicochemical characterization of sulfonylhydrazone
 derivatives designed as hypoglycemic agents
;
_journal_issue                   14
_journal_name_full               'New J. Chem.'
_journal_page_first              6464
_journal_page_last               6474
_journal_paper_doi               10.1039/C7NJ00074J
_journal_volume                  41
_journal_year                    2017
_chemical_compound_source        'from LASSBio'
_chemical_formula_moiety         'C17 H18 N2 O6 S'
_chemical_formula_sum            'C17 H18 N2 O6 S'
_chemical_formula_weight         378.40
_chemical_name_common            LASSBio-1773
_chemical_name_systematic
(E)-N'-(thiophen-2-ylmethylene)cyclohexanecarbohydrazide
_space_group_IT_number           19
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_atom_sites_solution_hydrogens   geom
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_audit_update_record
;
2017-01-03 deposited with the CCDC.
2017-05-29 downloaded from the CCDC.
;
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_computing_molecular_graphics    'Mercury 3.1'
_computing_publication_material  'Mercury 3.1'
_computing_structure_refinement  'TOPAS ACADEMIC 5'
_computing_structure_solution    'ab initio algorithm (DASH)'
_diffrn_ambient_pressure         100
_diffrn_ambient_temperature      298
_diffrn_measurement_device_type  'Stoe STADI-P diffractometer'
_diffrn_radiation_monochromator  none
_diffrn_radiation_probe          x-ray
_diffrn_radiation_type           'Cu K\a~1~'
_diffrn_radiation_wavelength     1.54056
_diffrn_source                   'sealed X-ray tube'
_diffrn_source_type              'Stoe STADI-P'
_exptl_absorpt_coefficient_mu    1.978
_exptl_absorpt_process_details
;
;
_exptl_crystal_colour            white
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_exptl_crystal_description       powder
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_pd_meas_scan_method             step
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_pd_proc_ls_background_function  '20-term Chebyschev polynomial'
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_pd_proc_ls_prof_wR_factor       0.06838
_pd_proc_number_of_points        4620
_pd_spec_mounting                'acetate foil'
_pd_spec_mount_mode              transmission
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_refine_ls_shift/su_mean         0.0001
_refine_ls_weighting_scheme      sigma
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_reflns_d_resolution_low         1.31495
_reflns_limit_h_max              10
_reflns_limit_h_min              0
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_cod_data_source_file            c7nj00074j2.cif
_cod_data_source_block           LASSBio_1773
_cod_database_code               7056253