A protocol for directly accessing geminal C-4 diarylated pyrazol-5(4<i>H</i>)-ones <i>via</i> tandem C-H aryne insertion and their inceptive neurobiological evaluation.
Sudarshana, K. A.; Sarma, Manas Jyoti; Radhakrishnan, Mydhili; Chakravarty, Sumana; Srihari, Pabbaraja; Mehta, Goverdhan; Organic & biomolecular chemistry 22 (2024) 714–719; doi:10.1039/d3ob01932b

data_7159724
_publ_section_title
;
 A protocol for directly accessing geminal C-4 diarylated
 pyrazol-5(4<i>H</i>)-ones <i>via</i> tandem C-H aryne insertion and their
 inceptive neurobiological evaluation.
;
_journal_issue                   4
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              714
_journal_page_last               719
_journal_paper_doi               10.1039/d3ob01932b
_journal_volume                  22
_journal_year                    2024
_chemical_formula_moiety         'C22 H18 N2 O'
_chemical_formula_sum            'C22 H18 N2 O'
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_audit_update_record
;
2022-05-30 deposited with the CCDC.	2023-12-19 downloaded from the CCDC.
;
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_diffrn_measurement_device_type  'Bruker D8 QUEST PHOTON-100'
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_refine_ls_extinction_expression Fc^*^=kFc[1+0.001xFc^2^\l^3^/sin(2\q)]^-1/4^
_refine_ls_extinction_method     'SHELXL-2018/3 (Sheldrick 2018)'
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_refine_ls_number_restraints     0
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0505P)^2^+0.3665P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_reflns_Friedel_coverage         0.000
_reflns_number_gt                3018
_reflns_number_total             4453
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d3ob01932b2.cif
_cod_data_source_block           KA921_0m
_cod_depositor_comments
'Adding full bibliography for 7159724--7159726.cif.'
_cod_original_sg_symbol_H-M      'P 21/c'
_cod_database_code               7159724
_shelx_shelxl_version_number     2018/3
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_shelx_res_checksum              83926