Development of catalytic deacylative alkylations (DaA) of 3-acyl-2-oxindoles: total synthesis of meso-chimonanthine and related alkaloids.
Kumar, Nivesh; Das, Mrinal Kanti; Ghosh, Santanu; Bisai, Alakesh; Chemical communications (Cambridge, England) 53 (2017) 2170–2173; doi:10.1039/c6cc10228j

data_7119503
_publ_section_title
;
 Development of catalytic deacylative alkylations (DaA) of
 3-acyl-2-oxindoles: total synthesis of meso-chimonanthine and related
 alkaloids.
;
_journal_issue                   13
_journal_name_full
'Chemical communications (Cambridge, England)'
_journal_page_first              2170
_journal_page_last               2173
_journal_paper_doi               10.1039/c6cc10228j
_journal_volume                  53
_journal_year                    2017
_chemical_formula_sum            'C24 H30 N4 O0'
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_chemical_name_systematic
;
 ?
;
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_space_group_name_Hall           '-P 2yn'
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_symmetry_space_group_name_Hall  '-P 2yn'
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_atom_sites_solution_hydrogens   geom
_audit_creation_method           SHELXL-2014
_audit_update_record
;
2016-10-04 deposited with the CCDC.
2017-01-19 downloaded from the CCDC.
;
_cell_angle_alpha                90
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_cell_measurement_theta_min      2.61
_cell_volume                     1975.44(17)
_computing_structure_refinement  'SHELXL-2014 (Sheldrick, 2014)'
_diffrn_ambient_temperature      296(2)
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_diffrn_measured_fraction_theta_max 0.997
_diffrn_measurement_device_type  'Bruker APEX-II CCD'
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_diffrn_reflns_av_unetI/netI     0.0578
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_diffrn_reflns_theta_full        25.242
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_diffrn_reflns_theta_min         1.949
_exptl_absorpt_coefficient_mu    0.076
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_refine_diff_density_max         0.462
_refine_diff_density_min         -0.455
_refine_diff_density_rms         0.059
_refine_ls_extinction_coef       0.0077(18)
_refine_ls_extinction_expression Fc^*^=kFc[1+0.001xFc^2^\l^3^/sin(2\q)]^-1/4^
_refine_ls_extinction_method     SHELXL
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_refine_ls_hydrogen_treatment    constr
_refine_ls_matrix_type           full
_refine_ls_number_parameters     254
_refine_ls_number_reflns         4656
_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      1.090
_refine_ls_R_factor_all          0.0999
_refine_ls_R_factor_gt           0.0595
_refine_ls_shift/su_max          0.000
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0896P)^2^+0.2762P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_reflns_threshold_expression     'I > 2\s(I)'
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_cod_depositor_comments          'Adding full bibliography for 7119503.cif.'
_cod_database_code               7119503
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