Intramolecular asymmetric propargylation of esters and imides: C-H functionalisation enables stereocontrolled access to UCS1025A.
Corcoran, James C.; Zhu, Jin; Semenick, Mason A.; Welser, Anna L.; Wang, Yi-Ming; Chemical science 16 (2025) 12879–12884; doi:10.1039/d5sc02523k

data_1574792
_publ_section_title
;
 Intramolecular asymmetric propargylation of esters and imides: C-H
 functionalisation enables stereocontrolled access to UCS1025A.
;
_journal_issue                   28
_journal_name_full               'Chemical science'
_journal_page_first              12879
_journal_page_last               12884
_journal_paper_doi               10.1039/d5sc02523k
_journal_volume                  16
_journal_year                    2025
_chemical_absolute_configuration ad
_chemical_formula_sum            'C23 H25 N O2 Si'
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_audit_update_record
;
2025-04-02 deposited with the CCDC.	2025-06-04 downloaded from the CCDC.
;
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_diffrn_reflns_point_group_measured_fraction_full 0.995
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_diffrn_reflns_theta_min         4.609
_diffrn_source                   'Bruker X8 Prospector Ultra Cu IMuS'
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_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details
;
 SADABS 2016/2: Krause, L., Herbst-Irmer, R., Sheldrick G.M. & Stalke D.,
 J. Appl. Cryst. 48 (2015) 3-10
;
_exptl_crystal_colour            colorless
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_exptl_crystal_recrystallization_method 'Evaporation from CDCl3'
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;
 Refined as an inversion twin.
;
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0478P)^2^+0.3697P] where P=(Fo^2^+2Fc^2^)/3'
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_cod_data_source_block           JCC902R_0m_a
_cod_depositor_comments
'Adding full bibliography for 1574791--1574792.cif.'
_cod_original_cell_volume        2055.0(7)
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