Development of a Highly Specific Rhodamine-Based Fluorescence Probe for Hypochlorous Acid and Its Application to Real-Time Imaging of Phagocytosis
Suguru Kenmoku; Yasuteru Urano; Hirotatsu Kojima; Tetsuo Nagano; Journal of the American Chemical Society 129 (2007) 7313–7318; doi:10.1021/ja068740g

data_4109493
_publ_section_title
;
 Development of a Highly Specific Rhodamine-Based Fluorescence Probe for
 Hypochlorous Acid and Its Application to Real-Time Imaging of
 Phagocytosis
;
_journal_name_full               'Journal of the American Chemical Society'
_journal_page_first              7313
_journal_page_last               7318
_journal_paper_doi               10.1021/ja068740g
_journal_volume                  129
_journal_year                    2007
_chemical_formula_moiety         'C24 H24 N2 O2 '
_chemical_formula_sum            'C24 H24 N2 O2'
_chemical_formula_weight         372.47
_space_group_IT_number           11
_symmetry_cell_setting           monoclinic
_symmetry_Int_Tables_number      11
_symmetry_space_group_name_Hall  '-P 2yb'
_symmetry_space_group_name_H-M   'P 1 21/m 1'
_cell_angle_alpha                90.0000
_cell_angle_beta                 96.612(3)
_cell_angle_gamma                90.0000
_cell_formula_units_Z            2
_cell_length_a                   6.6952(4)
_cell_length_b                   18.1555(14)
_cell_length_c                   7.9560(6)
_cell_measurement_reflns_used    8492
_cell_measurement_temperature    99.1
_cell_measurement_theta_max      27.5
_cell_measurement_theta_min      3.1
_cell_volume                     960.66(12)
_computing_cell_refinement       PROCESS-AUTO
_computing_data_collection       PROCESS-AUTO
_computing_data_reduction        CrystalStructure
_computing_publication_material  'CrystalStructure 3.7.0'
_computing_structure_refinement  CRYSTALS
_diffrn_detector_area_resol_mean 10.00
_diffrn_measured_fraction_theta_full 0.994
_diffrn_measured_fraction_theta_max 0.994
_diffrn_measurement_device_type  'Rigaku RAXIS-RAPID'
_diffrn_measurement_method       \w
_diffrn_radiation_type           'Mo K\a'
_diffrn_radiation_wavelength     0.71075
_diffrn_reflns_av_R_equivalents  0.036
_diffrn_reflns_limit_h_max       8
_diffrn_reflns_limit_h_min       -8
_diffrn_reflns_limit_k_max       23
_diffrn_reflns_limit_k_min       -23
_diffrn_reflns_limit_l_max       10
_diffrn_reflns_limit_l_min       -10
_diffrn_reflns_number            9154
_diffrn_reflns_theta_full        27.49
_diffrn_reflns_theta_max         27.49
_exptl_absorpt_coefficient_mu    0.082
_exptl_absorpt_correction_T_max  0.992
_exptl_absorpt_correction_T_min  0.750
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details
;
    Higashi, T. (1995). Program for Absorption Correction.
    Rigaku Corporation, Tokyo, Japan.
;
_exptl_crystal_colour            colorless
_exptl_crystal_density_diffrn    1.288
_exptl_crystal_description       prism
_exptl_crystal_F_000             396.00
_exptl_crystal_size_max          0.10
_exptl_crystal_size_mid          0.10
_exptl_crystal_size_min          0.10
_refine_diff_density_max         0.33
_refine_diff_density_min         -0.55
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   0.890
_refine_ls_hydrogen_treatment    refall
_refine_ls_number_parameters     194
_refine_ls_number_reflns         2266
_refine_ls_R_factor_gt           0.0489
_refine_ls_shift/su_max          0.0000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w = 1/[0.0010Fo^2^ + 3.0000\s(Fo^2^) + 0.5000]/(4Fo^2^)'
_refine_ls_weighting_scheme      calc
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_reflns_number_gt                1930
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_reflns_threshold_expression     F^2^>2.0\s(F^2^)
_cod_data_source_file            ja068740grom20061206_041230.cif
_cod_data_source_block           '_061025kemmoku'
_cod_original_formula_sum        'C24 H24 N2 O2 '
_cod_database_code               4109493