Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from Alkynes and Vinyl Azides.
Liu, Kai; Chen, Shuang; Li, Xing Guang; Liu, Pei Nian; The Journal of organic chemistry 81 (2016) 265–270; doi:10.1021/acs.joc.5b01995

data_4036445
_publ_section_title
;
 Multicomponent Cascade Synthesis of Trifluoroethyl Isoquinolines from
 Alkynes and Vinyl Azides.
;
_journal_issue                   1
_journal_name_full               'The Journal of organic chemistry'
_journal_page_first              265
_journal_page_last               270
_journal_paper_doi               10.1021/acs.joc.5b01995
_journal_volume                  81
_journal_year                    2016
_chemical_formula_sum            'C24 H18 F3 N O'
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_exptl_crystal_size_max          0.211
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_refine_ls_extinction_expression Fc^*^=kFc[1+0.001xFc^2^\l^3^/sin(2\q)]^-1/4^
_refine_ls_extinction_method     SHELXL
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_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      0.989
_refine_ls_R_factor_all          0.0761
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0458P)^2^+0.8882P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_cod_original_cell_volume        3810.3(7)
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_shelx_estimated_absorpt_t_min   0.978
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