Ciprofloxacin conjugated to diphenyltin(IV): a novel formulation with enhanced antimicrobial activity.
Chrysouli, M. P.; Banti, C. N.; Kourkoumelis, N.; Moushi, E. E.; Tasiopoulos, A. J.; Douvalis, A.; Papachristodoulou, C.; Hatzidimitriou, A. G.; Bakas, T.; Hadjikakou, S. K.; Dalton transactions (Cambridge, England : 2003) 49 (2020) 11522–11535; doi:10.1039/d0dt01665a

data_7704737
_publ_section_title
;
 Ciprofloxacin conjugated to diphenyltin(IV): a novel formulation with
 enhanced antimicrobial activity.
;
_journal_issue                   33
_journal_name_full
'Dalton transactions (Cambridge, England : 2003)'
_journal_page_first              11522
_journal_page_last               11535
_journal_paper_doi               10.1039/d0dt01665a
_journal_volume                  49
_journal_year                    2020
_chemical_formula_moiety         'C46 H44 F2 N6 O6 Sn'
_chemical_formula_sum            'C46 H44 F2 N6 O6 Sn'
_chemical_formula_weight         933.56
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_audit_update_record
;
2020-04-05 deposited with the CCDC.	2020-06-30 downloaded from the CCDC.
;
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_diffrn_ambient_temperature      100(2)
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_diffrn_source                   'micro-focus sealed X-ray tube'
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_exptl_absorpt_correction_T_max  1.00000
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_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details
;
CrysAlisPro 1.171.38.46 (Rigaku Oxford Diffraction, 2015)
Empirical absorption correction using spherical harmonics,
 implemented in SCALE3 ABSPACK scaling algorithm.
;
_exptl_crystal_colour            Colorless
_exptl_crystal_density_diffrn    1.183
_exptl_crystal_description       Rod
_exptl_crystal_F_000             1912
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_exptl_crystal_size_min          0.01
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_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      0.992
_refine_ls_R_factor_all          0.0654
_refine_ls_R_factor_gt           0.0523
_refine_ls_shift/su_max          0.001
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0827P)^2^] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1361
_refine_ls_wR_factor_ref         0.1428
_reflns_Friedel_coverage         0.000
_reflns_number_gt                3818
_reflns_number_total             4682
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d0dt01665a2.cif
_cod_data_source_block           shelx
_cod_depositor_comments
'Adding full bibliography for 7704737--7704738.cif.'
_cod_original_sg_symbol_H-M      'I 2/a'
_cod_database_code               7704737
_shelx_shelxl_version_number     2014/7
_oxdiff_exptl_absorpt_empirical_full_min 0.674
_oxdiff_exptl_absorpt_empirical_full_max 1.427
_oxdiff_exptl_absorpt_empirical_details
;
Empirical correction (ABSPACK) includes:
- Absorption correction using spherical harmonics
- Frame scaling
;
_shelx_res_checksum              86119
_shelx_fab_checksum              97904