A DBU-catalyzed Michael-Pinner-isomerization cascade reaction of 3-hydroxyoxindoles with isatylidene malononitriles: access to highly functionalized bispirooxindoles containing a fully substituted dihydrofuran motif.
Zhu, Yan-Shuo; Wang, Wen-Bo; Yuan, Bei-Bei; Li, Ya-Ning; Wang, Qi-Lin; Bu, Zhan-Wei; Organic & biomolecular chemistry 15 (2017) 984–990; doi:10.1039/c6ob02254e

data_7155425
_publ_section_title
;
 A DBU-catalyzed Michael-Pinner-isomerization cascade reaction of
 3-hydroxyoxindoles with isatylidene malononitriles: access to highly
 functionalized bispirooxindoles containing a fully substituted
 dihydrofuran motif.
;
_journal_issue                   4
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              984
_journal_page_last               990
_journal_paper_doi               10.1039/c6ob02254e
_journal_volume                  15
_journal_year                    2017
_chemical_formula_moiety         'C27 H19 Cl N4 O3, C4 H8 O2'
_chemical_formula_sum            'C31 H27 Cl N4 O5'
_chemical_formula_weight         571.01
_space_group_crystal_system      triclinic
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_space_group_name_Hall           '-P 1'
_space_group_name_H-M_alt        'P -1'
_symmetry_space_group_name_Hall  '-P 1'
_symmetry_space_group_name_H-M   'P -1'
_atom_sites_solution_hydrogens   geom
_atom_sites_solution_primary     direct
_atom_sites_solution_secondary   difmap
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_audit_update_record
;
2016-10-16 deposited with the CCDC.
2016-12-23 downloaded from the CCDC.
;
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_cell_volume                     1362.4(3)
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_computing_structure_refinement  'SHELXL-2014 (Sheldrick 2014)'
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_diffrn_ambient_temperature      100(2)
_diffrn_measured_fraction_theta_full 0.994
_diffrn_measured_fraction_theta_max 0.891
_diffrn_measurement_device_type  'Bruker APEX-II CCD'
_diffrn_measurement_method       '\f and \w scans'
_diffrn_radiation_type           MoK\a
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_refine_ls_extinction_method     none
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_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      1.037
_refine_ls_R_factor_all          0.0784
_refine_ls_R_factor_gt           0.0691
_refine_ls_shift/su_max          0.010
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.1019P)^2^+2.0822P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1856
_refine_ls_wR_factor_ref         0.1949
_reflns_Friedel_coverage         0.000
_reflns_number_gt                6675
_reflns_number_total             7791
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            c6ob02254e2.cif
_cod_data_source_block           mo_hd_wql1_0m_a
_cod_depositor_comments          'Adding full bibliography for 7155425.cif.'
_cod_database_code               7155425
_shelx_shelxl_version_number     2014/7
_shelx_estimated_absorpt_t_min   0.848
_shelx_estimated_absorpt_t_max   0.909
_shelx_res_checksum              44194