Selective synthesis of an elusive <i>C</i>-functional bis-cyclam and study of its inhibition of the CXCR4 chemokine receptor.
Le Roy, Marie M.; Claes, Sandra; Saffon-Merceron, Nathalie; Schols, Dominique; Troadec, Thibault; Tripier, Raphaël; Organic & biomolecular chemistry 22 (2024) 3059–3067; doi:10.1039/d3ob02050a

data_7159851
_publ_section_title
;
 Selective synthesis of an elusive <i>C</i>-functional bis-cyclam and
 study of its inhibition of the CXCR4 chemokine receptor.
;
_journal_issue                   15
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              3059
_journal_page_last               3067
_journal_paper_doi               10.1039/d3ob02050a
_journal_volume                  22
_journal_year                    2024
_chemical_formula_sum            'C36 H54 N8 O4'
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_audit_creation_method           SHELXL-2018/3
_audit_update_record
;
2022-12-07 deposited with the CCDC.	2024-03-11 downloaded from the CCDC.
;
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_diffrn_measurement_device_type  'Bruker kappa APEX-II CCD Quazar'
_diffrn_measurement_method       'phi and omega scans'
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.1294P)^2^+1.5512P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            d3ob02050a2.cif
_cod_data_source_block           4
_cod_depositor_comments          'Adding full bibliography for 7159851.cif.'
_cod_database_code               7159851
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