Unusual Reactivity of Isoquinolinones Generated by Silver-Catalyzed Cycloisomerizations of Imines Derived from ortho-Alkynylsalicylaldehydes.
Fernández, Patricia; Valdés, Carlos; Fañanás, Francisco J; Rodríguez, Félix; The Journal of organic chemistry 84 (2019) 3184–3191; doi:10.1021/acs.joc.8b03081

data_4033951
_publ_section_title
;
 Unusual Reactivity of Isoquinolinones Generated by Silver-Catalyzed
 Cycloisomerizations of Imines Derived from ortho-Alkynylsalicylaldehydes.
;
_journal_issue                   6
_journal_name_full               'The Journal of organic chemistry'
_journal_page_first              3184
_journal_page_last               3191
_journal_paper_doi               10.1021/acs.joc.8b03081
_journal_volume                  84
_journal_year                    2019
_chemical_formula_sum            'C28 H22 Cl N O5'
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_diffrn_ambient_temperature      298(2)
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_diffrn_reflns_point_group_measured_fraction_full 0.999
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_exptl_absorpt_process_details
;
CrysAlisPro 1.171.38.46 (Rigaku Oxford Diffraction, 2015)
Empirical absorption correction using spherical harmonics,
 implemented in SCALE3 ABSPACK scaling algorithm.
_exptl_special_details

;
_exptl_crystal_colour            white
_exptl_crystal_density_diffrn    1.350
_exptl_crystal_description       prism
_exptl_crystal_F_000             2032
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0686P)^2^+2.0046P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1196
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_reflns_number_gt                3837
_reflns_number_total             4478
_reflns_threshold_expression     'I > 2\s(I)'
_cod_data_source_file            jo8b03081_si_002.cif
_cod_data_source_block           6l
_cod_original_sg_symbol_H-M      'C 2/c'
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_shelx_res_checksum              89250
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