Ruthenium-Caged Antisense Morpholinos for Regulating Gene Expression in Zebrafish Embryos.
Griepenburg, J. C.; Rapp, T. L.; Carroll, P. J.; Eberwine, J.; Dmochowski, I. J.; Chemical science (Royal Society of Chemistry : 2010) 6 (2015) 2342–2346; doi:10.1039/C4SC03990D

data_1518605
_publ_section_title
;
 Ruthenium-Caged Antisense Morpholinos for Regulating Gene Expression in
 Zebrafish Embryos.
;
_journal_issue                   4
_journal_name_full
'Chemical science (Royal Society of Chemistry : 2010)'
_journal_page_first              2342
_journal_page_last               2346
_journal_paper_doi               10.1039/C4SC03990D
_journal_volume                  6
_journal_year                    2015
_chemical_formula_sum            'C83 H82 F24 N12 O5 P4 Ru2'
_chemical_formula_weight         2109.63
_space_group_IT_number           2
_symmetry_cell_setting           triclinic
_symmetry_Int_Tables_number      2
_symmetry_space_group_name_Hall  '-P 1'
_symmetry_space_group_name_H-M   'P -1'
_atom_sites_solution_hydrogens   geom
_atom_sites_solution_primary     direct
_audit_creation_method           SHELXL-97
_audit_update_record
;
2014-12-24 deposited with the CCDC.
2015-01-29 downloaded from the CCDC.
;
_cell_angle_alpha                70.206(3)
_cell_angle_beta                 85.323(3)
_cell_angle_gamma                67.450(2)
_cell_formula_units_Z            1
_cell_length_a                   11.2159(7)
_cell_length_b                   12.5550(8)
_cell_length_c                   18.1382(12)
_cell_measurement_temperature    100(1)
_cell_volume                     2216.1(3)
_computing_data_collection       'Bruker APEX2'
_computing_data_reduction        'Bruker SAINT'
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 2008)'
_computing_structure_solution    'SHELXS-97 (Sheldrick, 2008)'
_diffrn_ambient_temperature      100(1)
_diffrn_measured_fraction_theta_full 0.996
_diffrn_measured_fraction_theta_max 0.996
_diffrn_measurement_device       'CCD Area Detector'
_diffrn_measurement_device_type  'Bruker APEXII'
_diffrn_measurement_method       'phi and omega scans'
_diffrn_radiation_monochromator  graphite
_diffrn_radiation_source         'sealed tube'
_diffrn_radiation_type           MoK\a
_diffrn_radiation_wavelength     0.71073
_diffrn_reflns_av_R_equivalents  0.0189
_diffrn_reflns_av_sigmaI/netI    0.0107
_diffrn_reflns_limit_h_max       14
_diffrn_reflns_limit_h_min       -14
_diffrn_reflns_limit_k_max       16
_diffrn_reflns_limit_k_min       -16
_diffrn_reflns_limit_l_max       23
_diffrn_reflns_limit_l_min       -23
_diffrn_reflns_number            73021
_diffrn_reflns_theta_full        27.54
_diffrn_reflns_theta_max         27.54
_diffrn_reflns_theta_min         1.86
_exptl_absorpt_coefficient_mu    0.522
_exptl_absorpt_correction_T_max  0.7456
_exptl_absorpt_correction_T_min  0.6876
_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details   '(SADABS; Sheldrick, 2007)'
_exptl_crystal_density_diffrn    1.581
_exptl_crystal_density_method    'not measured'
_exptl_crystal_description       plate
_exptl_crystal_F_000             1068
_exptl_crystal_size_max          0.42
_exptl_crystal_size_mid          0.26
_exptl_crystal_size_min          0.10
_refine_diff_density_max         1.120
_refine_diff_density_min         -0.826
_refine_diff_density_rms         0.061
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   1.051
_refine_ls_hydrogen_treatment    constr
_refine_ls_matrix_type           full
_refine_ls_number_parameters     643
_refine_ls_number_reflns         10200
_refine_ls_number_restraints     122
_refine_ls_restrained_S_all      1.049
_refine_ls_R_factor_all          0.0292
_refine_ls_R_factor_gt           0.0266
_refine_ls_shift/su_max          0.002
_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'calc w=1/[\s^2^(Fo^2^)+(0.0241P)^2^+2.6125P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.0630
_refine_ls_wR_factor_ref         0.0655
_reflns_number_gt                9570
_reflns_number_total             10200
_reflns_threshold_expression     >2sigma(I)
_cod_data_source_file            c4sc03990d2.cif
_cod_data_source_block           UP9718
_cod_depositor_comments
;Adding full bibliography for 1518605.cif.

 Adding full bibliography for 1518605.cif.
;
_cod_original_cell_volume        2216.1(2)
_cod_original_sg_symbol_H-M      'P -1       '
_cod_database_code               1518605