Novel metallo-therapeutics of the NSAID naproxen. Interaction with intracellular components that leads the cells to apoptosis.
Banti, C. N.; Giannoulis, A. D.; Kourkoumelis, N.; Owczarzak, A. M.; Kubicki, M.; Hadjikakou, S. K.; Dalton transactions (Cambridge, England : 2003) 43 (2014) 6848–6863; doi:10.1039/c3dt53175a

data_7029546
_publ_section_title
;
 Novel metallo-therapeutics of the NSAID naproxen. Interaction with
 intracellular components that leads the cells to apoptosis.
;
_journal_issue                   18
_journal_name_full
'Dalton transactions (Cambridge, England : 2003)'
_journal_page_first              6848
_journal_page_last               6863
_journal_paper_doi               10.1039/c3dt53175a
_journal_volume                  43
_journal_year                    2014
_chemical_formula_sum            'C56 H55 Ag O3 P2'
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 ?
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CrysAlisPro, Oxford Diffraction Ltd.,
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CrysAlisPro, Oxford Diffraction Ltd.,
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CrysAlisPro, Oxford Diffraction Ltd.,
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_computing_molecular_graphics    'Mercury (McRae et al., 2008)'
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CrysAlisPro, Oxford Diffraction Ltd.,
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Empirical absorption correction using spherical harmonics,
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_exptl_crystal_colour            colourless
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_exptl_crystal_size_min          0.3
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_refine_ls_extinction_method     none
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_refine_ls_number_reflns         8478
_refine_ls_number_restraints     8
_refine_ls_restrained_S_all      1.069
_refine_ls_R_factor_all          0.0557
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0400P)^2^+2.1587P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1024
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_reflns_Friedel_coverage         0.000
_reflns_number_gt                7038
_reflns_number_total             8478
_reflns_threshold_expression     'I > 2\s(I)'
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_shelxl_version_number           2013-4
_shelx_res_checksum              17976