Synthesis, kinetic studies and molecular modeling of novel tacrine dimers as cholinesterase inhibitors.
de Aquino, Roney Anderson Nascimento; Modolo, Luzia Valentina; Alves, Rosemeire Brondi; de Fátima, Angelo; Organic & biomolecular chemistry 11 (2013) 8395–8409; doi:10.1039/c3ob41762j

data_7153200
_publ_section_title
;
 Synthesis, kinetic studies and molecular modeling of novel tacrine dimers
 as cholinesterase inhibitors.
;
_journal_issue                   48
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              8395
_journal_page_last               8409
_journal_paper_doi               10.1039/c3ob41762j
_journal_volume                  11
_journal_year                    2013
_chemical_formula_moiety         'C38 H36 N4, 2(C4 H F6 O4)'
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 ?
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;
CrysAlisPro, Oxford Diffraction Ltd.,
Version 1.171.34.34 (release 07-07-2010 CrysAlis171 .NET)
(compiled Jul  7 2010,16:04:54)
Empirical absorption correction using spherical harmonics,
 implemented in SCALE3 ABSPACK scaling algorithm.
;
_exptl_crystal_colour            orange
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_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'calc w=1/[\s^2^(Fo^2^)+(0.0679P)^2^+0.2464P] where P=(Fo^2^+2Fc^2^)/3'
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