Highly Enantioselective Phase-Transfer-Catalyzed Alkylation of Protected α-Amino Acid Amides toward Practical Asymmetric Synthesis of Vicinal Diamines, α-Amino Ketones, and α-Amino Alcohols
Takashi Ooi; Mifune Takeuchi; Daisuke Kato; Yukitaka Uematsu; Eiji Tayama; Daiki Sakai; Keiji Maruoka; Journal of the American Chemical Society 127 (2005) 5073–5083; doi:10.1021/ja0459328

data_4111611
_publ_contact_author_address
;
     Department of Chemistry, Graduate School of Science
     Kyoto University, Sakyo, Kyoto 606-8502 Japan
;
_publ_contact_author_email       maruoka@kuchem.kyoto-u.ac.jp
_publ_contact_author_fax         +81-75-753-4000
_publ_contact_author_name        'Keiji Maruoka'
_publ_contact_author_phone       +81-75-753-4041
_publ_section_title
;
 Highly Enantioselective Phase-Transfer-Catalyzed Alkylation of Protected
 \a-Amino Acid Amides toward Practical Asymmetric Synthesis of Vicinal
 Diamines, \a-Amino Ketones, and \a-Amino Alcohols
;
_journal_name_full               'Journal of the American Chemical Society'
_journal_page_first              5073
_journal_page_last               5083
_journal_paper_doi               10.1021/ja0459328
_journal_volume                  127
_journal_year                    2005
_chemical_formula_sum            'C34 H45 N3 O6'
_chemical_formula_weight         591.75
_space_group_IT_number           4
_symmetry_cell_setting           monoclinic
_symmetry_Int_Tables_number      4
_symmetry_space_group_name_Hall  'P 2yb'
_symmetry_space_group_name_H-M   'P 1 21 1'
_audit_creation_date             'Tue Jan  6 05:19:20 2004'
_audit_creation_method           'by teXsan'
_cell_angle_alpha                90
_cell_angle_beta                 102.89(2)
_cell_angle_gamma                90
_cell_formula_units_Z            2
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_cell_length_b                   10.679(6)
_cell_length_c                   14.299(9)
_cell_measurement_reflns_used    18272
_cell_measurement_temperature    296.2
_cell_measurement_theta_max      27.5
_cell_measurement_theta_min      3.1
_cell_volume                     1597.3(18)
_computing_cell_refinement       PROCESS-AUTO
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_computing_data_reduction        'teXsan Ver. 1.11'
_computing_publication_material  'teXsan Ver. 1.11'
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_computing_structure_solution    SIR92
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_diffrn_measured_fraction_theta_full 0.9920
_diffrn_measured_fraction_theta_max 0.9920
_diffrn_measurement_device_type  'Rigaku RAXIS-RAPID Imaging Plate'
_diffrn_measurement_method       \w
_diffrn_radiation_type           'Mo K\a'
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_diffrn_reflns_av_R_equivalents  0.031
_diffrn_reflns_limit_h_max       13
_diffrn_reflns_limit_h_min       -13
_diffrn_reflns_limit_k_max       13
_diffrn_reflns_limit_k_min       -13
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_diffrn_reflns_theta_max         27.48
_exptl_absorpt_coefficient_mu    0.084
_exptl_absorpt_correction_type   none
_exptl_crystal_colour            unknown
_exptl_crystal_density_diffrn    1.230
_exptl_crystal_description       unknown
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_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w = 1/[\s^2^(Fo^2^) + (0.05000(Max(Fo^2^,0) + 2Fc^2^)/3)^2^]'
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_reflns_threshold_expression     F^2^>2.0\s(F^2^)
_cod_data_source_file            ja0459328si20040727_035339.cif
_cod_data_source_block           Amino_Amide
_cod_original_cell_volume        1597(1)
_cod_original_formula_sum        'C34 H45 N3 O6 '
_cod_database_code               4111611