Unusual Nucleophilic Addition of Grignard Reagents in the Synthesis of 4-Amino-pyrimidines.
Tinson, Ryan A. J.; Hughes, David L.; Ward, Leanne; Stephenson, G. Richard; ACS omega 3 (2018) 8937–8944; doi:10.1021/acsomega.8b01137

data_4515925
_publ_section_title
;
 Unusual Nucleophilic Addition of Grignard Reagents in the Synthesis of
 4-Amino-pyrimidines.
;
_journal_issue                   8
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_journal_paper_doi               10.1021/acsomega.8b01137
_journal_volume                  3
_journal_year                    2018
_chemical_formula_moiety         'C7 H10 N4'
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1-cyano,2-amino,4,6-dimethyl-5,6-dihydro-3,5-pyrimidine
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CrysAlisPro, Agilent Technologies, Version 1.171.36.21 
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CrysAlisPro, Agilent Technologies, Version 1.171.36.21 
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CrysAlisPro, Agilent Technologies, Version 1.171.36.21 
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;
CrysAlisPro, Agilent Technologies,
Version 1.171.37.35 (release 13-08-2014 CrysAlis171 .NET)
(compiled Aug 13 2014,18:06:01)
Empirical absorption correction using spherical harmonics,
 implemented in SCALE3 ABSPACK scaling algorithm.
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_exptl_crystal_colour            colourless
_exptl_crystal_density_diffrn    1.198
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_refine_ls_number_restraints     0
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'w=1/[\s^2^(Fo^2^)+(0.0832P)^2^+0.0921P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
_refine_ls_wR_factor_gt          0.1379
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_reflns_number_total             2432
_reflns_threshold_expression     'I > 2\s(I)'
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_cod_data_source_block           ryant3
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