Superbase promoted synthesis of dienamides as useful intermediates for the synthesis of α-ketoamides, γ-lactams and cyclic imino ethers.
Blangetti, Marco; Deagostino, Annamaria; Gervasio, Giuliana; Marabello, Domenica; Prandi, Cristina; Venturello, Paolo; Organic & biomolecular chemistry 9 (2011) 2535–2538; doi:10.1039/c0ob00867b

data_7151761
_publ_section_title
;
 Superbase promoted synthesis of dienamides as useful intermediates for
 the synthesis of \a-ketoamides, \g-lactams and cyclic imino ethers.
;
_journal_issue                   7
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              2535
_journal_page_last               2538
_journal_paper_doi               10.1039/c0ob00867b
_journal_volume                  9
_journal_year                    2011
_chemical_formula_sum            'C18 H19 N O2'
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_audit_creation_date
;
'Sun Jan 24 07:24:21 2010'
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CrysAlis RED, Oxford Diffraction Ltd.,
Version 1.171.32.29 (release 10-06-2008 CrysAlis171 .NET)
(compiled Jun 10 2008,16:49:55)
;
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_computing_cell_refinement
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CrysAlis RED, Oxford Diffraction Ltd.,
Version 1.171.32.29 (release 10-06-2008 CrysAlis171 .NET)
(compiled Jun 10 2008,16:49:55)
;
_computing_data_collection
;
CrysAlis CCD, Oxford Diffraction Ltd.,
Version 1.171.32.29 (release 10-06-2008 CrysAlis171 .NET)
(compiled Jun 10 2008,16:49:55)
;
_computing_data_reduction
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CrysAlis RED, Oxford Diffraction Ltd.,
Version 1.171.32.29 (release 10-06-2008 CrysAlis171 .NET)
(compiled Jun 10 2008,16:49:55)
;
_computing_structure_refinement  'SHELXL-97 (Sheldrick, 1997)'
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_diffrn_ambient_temperature      293(2)
_diffrn_detector_area_resol_mean 10.2890
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;
1 omega -14.00 44.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- 19.5247 77.0000 0.0000 0.0000 0.0000 58

2 omega -14.00 98.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- 19.5247 77.0000 240.0000 0.0000 0.0000 112

3 omega 40.00 98.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- 19.5247 77.0000 90.0000 0.0000 0.0000 58

4 omega -54.00 3.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- -19.9935 77.0000 120.0000 0.0000 0.0000 57

5 omega 1.00 59.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- -19.9935 77.0000 330.0000 0.0000 0.0000 58

6 omega -36.00 5.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- -19.9935 77.0000 0.0000 0.0000 0.0000 41

7 omega -39.00 3.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- -19.9935 77.0000 60.0000 0.0000 0.0000 42

8 omega 4.00 57.00 1.0000 120.0000
omega____ theta____ kappa____ phi______ omega'___ theta'___ frames
- -19.9935 77.0000 90.0000 0.0000 0.0000 53

;
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_diffrn_orient_matrix_UB_31      0.0017647723
_diffrn_orient_matrix_UB_32      0.0786088566
_diffrn_orient_matrix_UB_33      -0.0088349636
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_diffrn_reflns_limit_h_max       16
_diffrn_reflns_limit_h_min       -21
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_diffrn_reflns_number            46490
_diffrn_reflns_theta_full        32.73
_diffrn_reflns_theta_max         32.6742
_diffrn_reflns_theta_min         2.9344
_exptl_absorpt_coefficient_mu    0.077
_exptl_absorpt_correction_T_max  1.00000
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_exptl_absorpt_correction_type   multi-scan
_exptl_absorpt_process_details
;
CrysAlis RED, Oxford Diffraction Ltd.,
Version 1.171.32.29 (release 10-06-2008 CrysAlis171 .NET)
(compiled Jun 10 2008,16:49:55)
Empirical absorption correction using spherical harmonics,
implemented in SCALE3 ABSPACK scaling algorithm.
;
_exptl_crystal_colour            colourless
_exptl_crystal_density_diffrn    1.179
_exptl_crystal_density_method    'not measured'
_exptl_crystal_description       prism
_exptl_crystal_F_000             1200
_exptl_crystal_size_max          0.10
_exptl_crystal_size_mid          0.12
_exptl_crystal_size_min          0.28
_refine_diff_density_max         0.315
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_refine_diff_density_rms         0.026
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   0.949
_refine_ls_hydrogen_treatment    noref
_refine_ls_matrix_type           full
_refine_ls_number_parameters     379
_refine_ls_number_reflns         10847
_refine_ls_number_restraints     0
_refine_ls_restrained_S_all      0.949
_refine_ls_R_factor_all          0.2104
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_refine_ls_shift/su_mean         0.000
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details
'calc w=1/[\s^2^(Fo^2^)+(0.0200P)^2^+0.0000P] where P=(Fo^2^+2Fc^2^)/3'
_refine_ls_weighting_scheme      calc
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_cod_data_source_file            c0ob00867b.txt
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