Three-Component Cycloadditions: The First Transition Metal-Catalyzed [5+2+1] Cycloaddition Reactions
Paul A. Wender; Gabriel G. Gamber; Robert D. Hubbard; Lei Zhang; Journal of the American Chemical Society 124 (2002) 2876–2877; doi:10.1021/ja0176301

data_4114701
_publ_contact_author             'Paul A. Wender'
_publ_contact_author_email       wenderp@leland.stanford.edu
_publ_section_title
;
 Three-Component Cycloadditions: The First Transition Metal-Catalyzed
 [5+2+1] Cycloaddition Reactions
;
_journal_name_full               'Journal of the American Chemical Society'
_journal_page_first              2876
_journal_page_last               2877
_journal_paper_doi               10.1021/ja0176301
_journal_volume                  124
_journal_year                    2002
_chemical_formula_moiety         'C14 H22 O4 Si '
_chemical_formula_sum            'C14 H22 O4 Si'
_chemical_formula_weight         282.41
_chemical_name_systematic
;
3a-Hydroxy-6-oxo-3-(trimethylsilyl)-1,3a,4,5,6,6a-tetrahydropentalene
-2-carboxylic acid ethyl ester
;
_space_group_IT_number           14
_symmetry_cell_setting           monoclinic
_symmetry_Int_Tables_number      14
_symmetry_space_group_name_Hall  '-P 2yn'
_symmetry_space_group_name_H-M   'P 1 21/n 1'
_audit_creation_date             2001-08-29
_audit_creation_method           'by CrystalStructure v2.00'
_cell_angle_alpha                90
_cell_angle_beta                 103.09(0)
_cell_angle_gamma                90
_cell_formula_units_Z            4
_cell_length_a                   8.470(0)
_cell_length_b                   11.582(1)
_cell_length_c                   16.209(1)
_cell_measurement_temperature    273.1
_cell_volume                     1548.78(16)
_computing_cell_refinement       Unknown
_computing_data_collection       Unknown
_computing_data_reduction        CrystalStructure
_computing_publication_material  'CrystalStructure Ver. 2.00'
_computing_structure_refinement  CRYSTALS
_computing_structure_solution    directMethod
_diffrn_measured_fraction_theta_full 0.9537
_diffrn_measured_fraction_theta_max 0.9537
_diffrn_radiation_type           'Mo K\a'
_diffrn_radiation_wavelength     0.7107
_diffrn_reflns_av_R_equivalents  0.064
_diffrn_reflns_limit_h_max       9
_diffrn_reflns_limit_h_min       0
_diffrn_reflns_limit_k_max       13
_diffrn_reflns_limit_k_min       -13
_diffrn_reflns_limit_l_max       17
_diffrn_reflns_limit_l_min       -18
_diffrn_reflns_number            2649
_diffrn_reflns_theta_full        24.71
_diffrn_reflns_theta_max         24.71
_exptl_absorpt_coefficient_mu    0.159
_exptl_absorpt_correction_type   none
_exptl_crystal_colour            colorless
_exptl_crystal_density_diffrn    1.211
_exptl_crystal_description       rhombic
_exptl_crystal_preparation       'CDCl3 (evaporation)'
_exptl_crystal_size_max          0.20
_exptl_crystal_size_mid          0.35
_exptl_crystal_size_min          0.45
_refine_diff_density_max         0.37
_refine_diff_density_min         -0.38
_refine_ls_extinction_method     none
_refine_ls_goodness_of_fit_ref   1.416
_refine_ls_hydrogen_treatment    refall
_refine_ls_number_parameters     197
_refine_ls_number_reflns         2520
_refine_ls_R_factor_gt           0.0470
_refine_ls_shift/su_max          0.0110
_refine_ls_structure_factor_coef Fsqd
_refine_ls_weighting_details     'w = 1/\s^2^(Fo^2^)'
_refine_ls_weighting_scheme      sigma
_refine_ls_wR_factor_ref         0.1130
_reflns_number_gt                2030
_reflns_number_total             2648
_reflns_threshold_expression     F^2^>2.0\s(F^2^)
_cod_data_source_file            ja0176301_s2_3.cif
_cod_data_source_block           '_compound_21_data'
_cod_original_cell_volume        1548.8(0)
_cod_original_formula_sum        'C14 H22 O4 Si '
_cod_database_code               4114701