Syntheses of α-CF<sub>3</sub>-α-quaternary ketones via p-quinone methides and their derivatization to compounds with successively congested stereogenic centers.
Terashima, Kyu; Kawasaki-Takasuka, Tomoko; Agou, Tomohiro; Kubota, Toshio; Yamazaki, Takashi; Organic & biomolecular chemistry 18 (2020) 4638–4644; doi:10.1039/d0ob00951b

data_7157530
_publ_section_title
;
 Syntheses of \a-CF<sub>3</sub>-\a-quaternary ketones via p-quinone
 methides and their derivatization to compounds with successively
 congested stereogenic centers.
;
_journal_issue                   24
_journal_name_full               'Organic &amp; biomolecular chemistry'
_journal_page_first              4638
_journal_page_last               4644
_journal_paper_doi               10.1039/d0ob00951b
_journal_volume                  18
_journal_year                    2020
_chemical_formula_moiety         'C22 H18 Cl F3 O2, C4 H8 O2'
_chemical_formula_sum            'C26 H26 Cl F3 O4'
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;
2020-03-27 deposited with the CCDC.	2020-06-03 downloaded from the CCDC.
;
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;
CrysAlisPro 1.171.38.43 (Rigaku Oxford Diffraction, 2015)
Empirical absorption correction using spherical harmonics,
 implemented in SCALE3 ABSPACK scaling algorithm.
;
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'w=1/[\s^2^(Fo^2^)+(0.0729P)^2^+1.5111P] where P=(Fo^2^+2Fc^2^)/3'
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'Adding full bibliography for 7157528--7157531.cif.'
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_oxdiff_exptl_absorpt_empirical_details
;
Empirical correction (ABSPACK) includes:
- Absorption correction using spherical harmonics
- Frame scaling
;
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