Tolvaptan-Type Vasopressin Receptor Ligands: Important Role of Axial Chirality in the Active Form.
Tabata, Hidetsugu; Yoneda, Tetsuya; Oshitari, Tetsuta; Takahashi, Hideyo; Natsugari, Hideaki; Journal of medicinal chemistry 60 (2017) 4503–4509; doi:10.1021/acs.jmedchem.7b00422

data_1546199
_publ_section_title
;
 Tolvaptan-Type Vasopressin Receptor Ligands: Important Role of Axial
 Chirality in the Active Form.
;
_journal_issue                   10
_journal_name_full               'Journal of medicinal chemistry'
_journal_page_first              4503
_journal_page_last               4509
_journal_paper_doi               10.1021/acs.jmedchem.7b00422
_journal_volume                  60
_journal_year                    2017
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_cell_angle_beta                 90.0000
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_diffrn_measured_fraction_theta_max 1.000
_diffrn_measurement_device_type  'Rigaku R-AXIS RAPID'
_diffrn_measurement_method       \w
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'Flack, H. D. (1983), Acta Cryst. A39, 876-881.  1639 Friedel Pairs'
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'w = 1/[\s^2^(Fo^2^)+(0.1000P)^2^] where P=(Fo^2^+2Fc^2^)/3'
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_cod_original_cell_volume        2098.49(7)
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