Question: is it possible to drive from panama to colombia

Answer: No, The Darién Gap (Spanish: Región del Darién or Tapón del Darién) is a break in the Pan-American Highway consisting of a large swath of undeveloped swampland and forest within Panama's Darién Province in Central America and the northern portion of Colombia's Chocó Department in South America. The gap begins in Yaviza, Panama and ends in Turbo, Colombia, stretching between 100 km and 160 km (60--100 miles) long. Roadbuilding through this area is expensive, and the environmental cost is high. Political consensus in favor of road construction has not emerged. Consequently, there is no road connection through the Darién Gap connecting North America with South America and it is the missing link of the Pan-American Highway.