Question: does me before you have a sad ending

Answer: Yes, On the night of Will's flight to Switzerland, Louisa visits him one last time. They agree that the past six months have been the best in their lives. He dies shortly after in the clinic, and it is revealed that he left Louisa a considerable inheritance, meant to continue her education and to fully experience life. The novel ends with Louisa at a café in Paris, reading Will's last words to her in a letter, that tell her to 'live well'.