Question: do great white sharks have any natural predators

Answer: No, The great white shark has no known natural predators other than, on very rare occasions, the killer whale. The great white shark is arguably the world's largest known extant macropredatory fish, and is one of the primary predators of marine mammals. It is also known to prey upon a variety of other marine animals, including fish and seabirds. It is the only known surviving species of its genus Carcharodon, and is ranked first in having the most recorded shark bite incidents on humans.