Question: At concentrations of 0.1-1 µg/ml colchicine, a natural plant product, can cause the mitotic arrest of dividing cells at metaphase through disrupting the spindle apparatus. Colchicine interferes with which of these cell functions during cell division?

  Options: 
 A. microtubule organization of spindle fibers
 B. DNA synthesis of spindle protein
 C. membrane transport of spindle fibers
 D. RNA synthesis of spindle protein
Answer: A