a sleep extension pilot study in adults with obesity

Conditions: Obesity; Sleep; Weight, Body; Eating Behavior; Blood Pressure; Quality of Life

Summary: the pilot study will test the feasibility of a 16-week sleep extension intervention, in adults with obesity, to increase nighttime sleep duration, as well as reduce daytime sleepiness and sleep-related disturbance. the study will also examine changes in weight, eating behaviors, wellbeing, and blood pressure across the 16-week intervention .

short sleep duration (\ 30 kg/m2). additional secondary outcomes of changes in weight, eating behaviors, wellbeing, and blood pressure will also be assessed. if results are positive, the protocol will be used to secure external funding for a larger randomized clinical trial.

Eligibility criteria:
inclusion criteria: 1. adults, aged 18-50 years old, 2. all genders 3. body mass index within the obese weight status (bmi of ≥ 30 kg/m2) 4. short sleep duration, defined as sleeping, on average, \<6.5 hours/night for at least 5 nights/week 5. sleep patterns must be stable for the past 6 months 6. weight must be stable (+/- 10 lb) for the past 6 months 7. if taking medication for medical or mental health conditions, the condition must be well-controlled with stable dosage (i.e., at least 3 months) 8. note: individuals with and without insomnia will be eligible to participate to increase generalizability of the findings. also, individuals with known obstructive sleep apnea that is being treated and individuals who fall below the "very high risk" category for obstructive sleep apnea (on the ares screening questionnaire) will be included. 9. participants must provide a completed form for study participation from their primary care provider to confirm that it is safe from a medical perspective exclusion criteria: 1. specific chronic sleep disorders (e.g., untreated or at very high risk for obstructive sleep apnea, restless leg syndrome, parasomnias, narcolepsy, central apnea, chronic fatigue syndrome, or fibromyalgia) 2. extreme chronotype (i.e., extreme morning or evening sleep patterns) 3. work schedule that is not compatible with sleep habit changes (e.g., night shifts, rotating shift work, or long driving) 4. chronic use of sleep aid or anticonvulsant medications 5. chronic organ disorders (e.g., untreated or uncontrolled diabetes, other endocrine disorders, copd, chronic cardiac arrhythmia, uncontrolled hypertension or gastro-esophageal disorders) 6. current enrollment in a weight loss program or any active weight loss attempt (e.g., self-directed diet/exercise, over-the-counter supplements, weight management medication) 7. history of bariatric surgery (with the exception of an adjustable gastric band that has been removed) 8. mental health disorders judged severe (e.g., major depression, eating disorders, anxiety disorders, bipolar disorder/mania, schizophrenia, active suicidal ideation) 9. substance use (e.g., illicit drugs, marijuana dependence, excessive caffeine intake, smoking/tobacco use) 10. planned move outside of the philadelphia area in the next 6 months 11. planned travel across time zones during the study period 12. family factors that may interfere with adherence to the study protocol (e.g., infants and young children that consistently disrupt their sleep schedule; partner, other individuals, or pets that would make compliance difficult) 13. pregnancy or lactation or plans to become pregnant during the study period 14. menopause 15. any other contraindication to participation as determined by the study team

Keywords: short sleep duration sleep extension obesity eating behavior blood pressure