changes in physical activity in all day life in people with ms before and after rehabilitation

Conditions: Rehabilitation

Summary: the primary objective is to observe the impact of in-patient rehabilitation on physical activity in daily life using miniature, wearable sensors, fixed on the shoes. these sensors record data about various aspects of walking. the information on the therapy effect on daily life can complement the clinical information and the patients' subjective report on therapy induced improvements. the secondary objective is the association of changes in physical activity, self-rated walking capacity, self-rated fatigue and self-rated health-related quality of life, wich will be analysed for disease severity of the participants.

gait disorders are common in patients with multiple sclerosis (pwms). multidisciplinary in-patient rehabilitation conducted by specialized doctors, nurses and therapists can improve the ability to walk by tackling the problem with various approaches: by increasing strength in leg muscles, by improving balance, by increasing cardio- pulmonary fitness, by fitting walking aids, by reducing fatigue and cognitive deficits, by working out strategies to compensate for impairments, and by optimising medical treatment. the investigator's patients, who spend a lot of time (usually 2- 4 weeks) and effort for in-patient rehabilitation in valens tell us, that this intensive therapy is usually effective and that their walking ability improves to a degree that is relevant in daily life. the scientific evidence for the effectiveness of in- patient rehabilitation is usually based on either clinical assessments of function (e.g. the 6 minute walking test) or on reports from pwms, by using questionnaires e.g. about mobility or quality of life in daily life. although clinical assessments provide important information about improvements of the functional capacity, they do not provide information about the impact of therapy on daily life. patient reports, on the other hand, provide important information about the perceived impact in daily life, but the information is not objective. objective information about the impact of rehabilitation on daily life is usually not available. the primary objective therefore is to observe the impact of in-patient rehabilitation on physical activity in daily life using miniature, wearable sensors, fixed on the shoes. these sensors record data about various aspects of walking. the information on the therapy effect on daily life can complement the clinical information and the patients' subjective report on therapy induced improvements. the secondary objective is the association of changes in physical activity, self-rated walking capacity, self-rated fatigue and self-rated health-related quality of life, wich will be analysed for disease severity of the participants.

Eligibility criteria:
inclusion criteria: * planed rehabilitation in valens between january 2018 and june 2019 * edss 2.0-6.5 (an edss 6.5 means the ability to walk 20 meters without resting, using constant bilateral assistance) * german speaking * good function of upper limb, that the device can be fixed by participant himself * informed consent

Keywords: multiple sclerosis in-patient rehabilitation all day life activities walking capacity fatigue quality of life