active you: walk, dance, and tone your abs to reduce your risk of diabetes

Conditions: Obesity

Summary: the phenomenon of physical activity (pa) avoidance in obesity has been detailed in the literature, but there is a lack of programs designed to address the root causes. in addition to common pa barriers such as lack of time, individuals with obesity face weight-related impediments, including stigma, shame, poor fitness, and low exercise self-efficacy, which reduce their engagement in pa. these impediments have been observed in white and minoritized populations. numerous studies have suggested that individuals with obesity prefer activities that are enjoyable, less exhausting, and conveniently available in settings where they are not exposed to stigma. the studies also point to a need for programs that focus on the general health benefits of pa rather than weight loss, which although desirable, can be elusive. unmet weight loss expectations contribute to high dropout rates and non-adherence to the prescribed pa regimen among those with obesity. this is particularly consequential for minoritized populations including african americans who tend to lose less weight in lifestyle interventions but achieve significant improvements in many cardiometabolic outcomes. in this proposal, investigators present pa as a buffer against the deleterious effects of obesity, agnostic of weight loss status. the physical activity for the heart (path) program was intentionally designed to provide vicarious experiences for diverse individuals with obesity, by featuring their peers in body size, fitness level, and age engaging in pa. the impact of the path intervention on these biomarkers will provide important insights into the mechanisms via which a combination of popular pa modalities improves cardiometabolic outcomes in the context of obesity.

the proposed research is significant because it will provide key evidence supporting the use of curated, openly sourced content to address pa barriers in obesity. physical activity for the heart (path) intervention, which is anchored on the social cognitive theory's (sct) premise that observing similar (i.e. body type, fitness level, age) others succeed can motivate action and help demonstrate a plan for success. thus proposal will examine the feasibility of using path in a weight-neutral context and the preliminary effects on adipocytokines that influence insulin resistance. if path improves pa and adipocytokines, it could provide a highly scalable tool for mitigating the risk of cardiometabolic disease, especially among those looking for weight-agnostic pa programs. the walking, dance, and abdominal core workouts to be examined in this proposal are extremely popular and abundant on youtube, which makes it easy to access and curate content that can be tailored to individual preferences. the highly scalable path program is accessible at any time in any setting and can lessen the impact of unpredictable barriers to pa such as inclement weather or pandemics.

Eligibility criteria:
inclusion criteria: * age ≥18 years, body mass index (bmi) ≥30kg/m2, * regular access to the internet, * self-monitoring of pa via waist worn actigraph during run-in (≥4 days with ≥10hrs wear time), * self-reported non-adherence to pa guidelines \[\<150 min of moderate to vigorous physical activities (mvpa/wk)\]. exclusion criteria: * pregnancy/intention to become pregnant within 12 weeks, * involvement in litigation related to a health issue, or a condition that requires supervised pa (e.g., stroke). * individuals with a history of cerebrovascular disease (cvd), type 2 diabetes (t2d), * any affirmative response to any question in the physical activity readiness questionnaire (par-q) will require primary care physician (pcp) clearance before enrollment.

Keywords: physical activity workouts adipocytokines