Kornimate/medical-research-clean huggingface dataset:
can the enhanced transtheoretical model intervention (etmi) be implemented in a public health organization

Conditions: Low Back Pain

Summary: the aim of this study is to assess whether the etmi method can be implemented among primary care practitioners in the central district of maccabi health services and examine whether it provides a medical and economic advantage.

an implementation study- a prospective cohort study with pre- and post-intervention by retrieving economic and therapeutic outcome data from mhs databases. the intervention group will be the central district of mhs, among 220 primary care practitioners (100 physicians and 120 physiotherapists) and their patients (n=7,000) who suffer from back pain and receive treatment. we will investigate the relationship between the care received and outcomes in terms of healthcare utilization, costs, and patient-relevant outcomes.

Eligibility criteria:
inclusion criteria: * primary care practitioners and their patients, who suffer from back pain and receive treatment. * patients who suffer from back pain and receive treatment with or without leg radiation exclusion criteria: * no

Keywords: low back pain implementation study enhanced transtheoretical model intervention public health
compliance in non invasive mechanical ventilation

Conditions: Respiratory Insufficiency

Summary: database study of the adherence to treatment to non-invasive mechanical ventilation


Eligibility criteria:
inclusion criteria: * patients in non invasive mechanical ventilation and affiliated by the respiratory centre of the east of denmark * registered in telemedical solution in the period from 01.01.2020 to 04.01.2022 * age above 18 years exclusion criteria: -
investigation on the epidemic prevention effect of using chinese medicine during the severe acute respiratory syndrome coronavirus 2 (sars-cov-2) outbreak.

Conditions: COVID-19 Pandemic

Summary: taking a regional hospital as an example, the investigators will discuss the changes in the community cumulative incidence rate(cir) and the epidemic prevention effect of using chinese medicine during the sars-cov-2 outbreak. main purpose: retrospective case study to explore the effect of traditional chinese medicine on the prevention of sars-cov-2. secondary purpose: if there are related side effects after taking chinese medicine.

the large-scale coronavirus epidemic is a major global public health challenge in the 21st century. since the 2003 severe acute respiratory syndrome (sars) epidemic spread globally and caused hundreds of deaths, the middle east respiratory syndrome (middle east respiratory syndrome, mers) and coronavirus disease 2019(covid-19) has caused a large-scale global spread and also caused a huge impact on the public health and medical system. in the country's current epidemic (aug 1, 2021), more than 15,000 people have been diagnosed, and the number of deaths has exceeded 800. among them, the taipei epidemic is the most severe, and the wanhua district of taipei city is the hot zone. the investigators will discuss the changes in accumulation incidence rate(cir) of the community and the epidemic prevention effect of using chinese medicine during the sars-cov-2 outbreak. this is a retrospective case study to explore the effect of traditional chinese medicine on the prevention of sars-cov-2 and discuss if there are related side effects after taking chinese medicine.

Eligibility criteria:
inclusion criteria: - from january 1, 2020 to july 31, 2021, chinese medicine is used for patients with new coronary pneumonia epidemic prevention. exclusion criteria: 1. patients who do not use traditional chinese medicine for the prevention of new coronary pneumonia. 2. patients who have signed and refused to provide medical records.

Keywords: chinese medicine
the effect of subtalar joint antipronation taping on the dynamic knee valgus in female volleyball players with low medial arch

Conditions: Anterior Cruciate Ligament Rupture

Summary: this study aims to investigate the biomechanical mechanisms of dynamic knee valgus and the impact of subtalar pronation, particularly due to decreased medial longitudinal arch, on knee injury risk, highlighting the importance of prevention and intervention strategies for athlete health.

dynamic knee valgus is an abnormal movement pattern of the lower extremity, formed by the combination of femoral adduction and internal rotation, tibial abduction and internal rotation, and subtalar pronation, and it is a significant risk factor for knee injuries. the foot and ankle represent the first link in the lower extremity kinetic chain, and a mechanical relationship between subtalar joint motion and tibial rotation triggers internal rotation of the tibia during weight-bearing. this is particularly more pronounced in female athletes, as increased foot pronation and medial longitudinal arch (mla) drop contribute to dynamic knee valgus. supporting the mla has become increasingly important in injury prevention, as there is evidence in the literature showing that interventions to reduce foot pronation decrease dynamic knee valgus and help prevent patellofemoral pain and anterior cruciate ligament injuries. the aim of this study is to investigate the effects of antipronation taping on dynamic knee valgus and knee flexion angle during functional jump tests in female volleyball players with mla drop. innovative taping materials, such as dynamic tape, when applied correctly, can support the mla, reduce tibial rotation, and decrease abnormal movements. while there is existing evidence that mla-supporting orthotics reduce such injury risks, no studies have specifically examined antipronation taping with dynamic tape applied to the subtalar joint. this study seeks to explore modifiable risk factors associated with common knee injuries in female athletes from a foot posture perspective and contribute to athlete health.

Eligibility criteria:
inclusion criteria: actively playing volleyball for at least 5 years, a drop of 10 mm or more in the navicular drop test, a score of ≥ +4 according to the a foot posture index. exclusion criteria: a history of lower extremity injury within the last 3 months, a history of ankle and/or knee surgery, having non-structural instability, a history of congenital or traumatic deformity in the lower extremity.

Keywords: pes planus acl dynamic tape
media use in preschooler study (mups)

Conditions: Obesity

Summary: childhood obesity is an epidemic and increasing. there are very few effective treatments for obesity in children. recent studies have shown an association between obesity and sedentary behaviors such as television, video viewing and playing video games ('screen time') in preschool aged children. a school based intervention to reduce screen time in older children has been effective in preventing obesity. the reduction of screen time may lead to the prevention of obesity and its complications in preschool children.

there have been no trials examining an intervention to decrease screen time in preschool children in the physician office setting. this setting is appealing for interventions directed to preschool children because of accessibility. in addition, other public health interventions implemented in a physician office setting, such as home safety advice, have been effective. the proposed study design will be a randomized controlled trial. the intervention group will receive the study intervention, which is a 15 minute session about the health impact of screen time in children and strategies to decrease screen time. the objective of this study is to determine if an office based intervention is effective in decreasing screen time (television, video viewing and playing video games) in preschool children.

Eligibility criteria:
inclusion criteria: * registered to attend a 3 year old well child visit exclusion criteria: * children with limitations in ambulation or cognitive delay will be excluded from the study.

Keywords: pediatrics media mups
deep brain stimulation (dbs) retrospective outcomes study

Conditions: Parkinson Disease; Essential Tremor; Dystonia

Summary: the primary objective of this study is to characterize real-world clinical outcomes of deep brain stimulation (dbs) using retrospective review of de-identified patient records.

the purpose of this study is to characterize 1. real-world clinical outcomes of deep brain stimulation (dbs) using retrospective review of de-identified patient records.

Eligibility criteria:
inclusion criteria: * must be previously treated with or eligible for implantation with a deep brain stimulation system exclusion criteria: * no exclusion criteria
real clinical practice register of albuminuria detection in patients with previously undiagnosed chronic kidney disease

Conditions: Chronic Kidney Diseases; Hypertension; Chronic Heart Failure; Ischemic Heart Disease; Atrial Fibrillation; PreDiabetes; Chronic Obstructive Pulmonary Disease; Cancer; Urolithiasis; COVID-19

Summary: real clinical practice register of albuminuria detection in patients with previously undiagnosed chronic kidney disease

this register was sponsored and organized by the association "eurasian association of internal medicine". it is a multicenter non-interventional register of real clinical practice. the database will include patients aged 40 years and older without pre-existing nephrological disease who are available for a dipstick test for albuminuria. the subjects will be identified by screening all patients who meet inclusion/exclusion criteria during routine outpatient and hospital follow-up. the register does not include follow-up (cross-sectional design). patients eligible for the register should be enrolled and documented. the procedure for obtaining informed consent for the collection and analysis of the retrospective data must comply with the local legislation. if necessary, patients will be asked to sign an informed consent document. all study sites will use standardized electronic crfs. the electronic data capture (edc) system should be validated in accordance with current standards and legal requirements. the investigators will log into this system using individual usernames and passwords. data may only be entered and corrected by the investigator or other authorized study site personnel.

Eligibility criteria:
inclusion criteria: * men and women aged 40 and older at the time of data entry; * a possibility to check for albuminuria using dipsticks and/or analysis for microalbuminuria or albumin-to-creatinine ratio in a single urine sample. exclusion criteria: * unwillingness of the patient to participate in the register; * diagnosis of ckd made before the screening for the register; * diagnosis of diabetes mellitus (dm) type 1 or type 2 made before the screening for the register; * pregnancy; * long distance running or very strenuous physical activity in the last 24 hours.

Keywords: albumin-to-creatinine ratio albuminuria microalbuminuria chronic kidney diseases estimation of glomerular filtration rate
the effect of therapeutic touch and emotional freedom technique on postpartum mood and fatigue in postpartum women

Conditions: Fatigue; Emotion Regulation

Summary: therapeutic touch (td) is a non-pharmacological/integrated treatment method used to balance the body by regulating the imbalanced energy field in the individual or resolving blockages in energy flow. emotional freedom technique (eft) is a psychophysiological intervention that combines elements of somatic stimulation using acupuncture points. this research will be conducted as a randomized controlled experimental study to determine the effect of td and eft intervention on postpartum mood and fatigue in postpartum women. the research will be conducted between november 2023 and november 2024 with women who gave birth normally and are registered at karakulak family health center in konya. this research; it was planned to be carried out with three groups: td intervention, eft intervention and control group. the population of the research consists of women who gave birth vaginally and those who gave birth vaginally in the relevant hospital.


Eligibility criteria:
inclusion criteria: * having a vaginal birth at term * being primiparous * postpartum 3rd-5th. to be in the days * being able to speak and understand turkish * being 18 years or older * having a single and viable fetus * volunteering to participate in research * not having experienced td or eft treatment before exclusion criteria: * a psychiatric diagnosis has been made, * having a chronic systemic disease, * the newborn's need for treatment * having postpartum complications in the mother or baby * those who have sensitivity or problems with touch, * wounds, infections, etc. in places that need to be touched. existence of situations, * women who have any disability that would prevent communication (deafness, hearing impairment, etc., use of languages other than turkish) will be excluded from the research.

Keywords: emotional freedom technic therapeutic touch fatigue mood state level
reverse innovation and patient engagement to improve quality of care and patient outcomes

Conditions: Diabetes; Cardiovascular Disease; Substance Abuse Disorder; Mental Health Disorder

Summary: project connect ("community-based organizations neighborhood network: enhancing capacity together") is a randomized controlled trial that involves 22 community-based organizations (cbos) located in baltimore, md. half of these organizations were randomly assigned to the intervention group using a constrained cluster randomization process. the remaining 11 are a part of the control intervention group. the intervention is a co-developed set of it tools hypothesized to improve the connections among intervention cbos, johns hopkins health care facilities and cbo clients.

see above

Eligibility criteria:
inclusion criteria: community based organization; 501-c3 status; located within zip codes surrounding johns hopkins hospital and johns hopkins bayview medical center; provides direct services to clients exclusion criteria: part of johns hopkins medicine or baltimore city agency

Keywords: community based organization reverse innovation social services referral chronic disease
reversing glucose and lipid-mediated vascular dysfunction

Conditions: Blood Pressure; Hypertension

Summary: the purpose of our study is to understand the extent to which the blood vessels are affected by glucose and fat (lipids) in lean healthy adults and if these changes in the blood vessels contribute to the development of high blood pressure.

hypertension, obesity, and insulin resistance are associated with elevated muscle sympathetic nerve activity (msna), which is important for blood pressure regulation. the measurement of msna is safely performed in humans using the microneurographic technique that involves recording sympathetic nerve activity projecting to skeletal muscle using a small microelectrode at the peroneal nerve near the knee. the health of your blood vessels will be tested in this study, in addition to the activity of the nerves that control the blood vessels. the function of the nerves and blood vessels can be diminished by high blood glucose and lipids, and we will test the ability of a well-known antioxidant, ascorbic acid (vitamin c), to restore the function of the nerves and blood vessels.

Eligibility criteria:
inclusion criteria: * lean: bmi \< 25 kg/m * normal insulin sensitivity: (calculation based on fasting glucose and insulin concentrations in blood) * middle-aged: 18-79 years * blood pressure: \< 140 (systolic) and \< 90 mmhg (diastolic * weight stable (+/- 5 lbs) for the previous 3 months * participants must be willing and able to discontinue taking any vitamin c or e supplements or omega-3 fatty acids beginning 2 weeks prior. * able and willing to provide written informed consent exclusion criteria: * diabetes mellitus type i or type ii: fasting glucose \< 126 mg/dl and/or hba1c \< 6.5% * current smoker or history of smoking in the past 3 months. * hyperlipidemia: fasting triglycerides \< 250 mg/dl * hypertension: \>130/80 mmhg * history of heart disease (e.g., myocardial infarction, stent, heart attack, stroke, heart failure, valvular heart disease, cardiomyopathy) * history of vascular disease (e.g., bypass, stroke)
optimom kindergarten study

Conditions: Infant, Very Low Birth Weight

Summary: in canada, the leading cause of long-term disability in children is being born at very low birth weight (vlbw). to help improve outcomes, nutrition is a modifiable aspect of infant care. mother's milk is the optimal way to feed vlbw infants; however, many need a supplement of donor milk or preterm formula as not enough mother's milk is available. as the ideal supplement for prolonged feeding and its long-term effects is currently unknown, this study is a prospective follow up of vlbw infants who in hospital were fed: donor milk or preterm formula and/or mother's milk. areas of development to be assessed include: cognition, language, motor skills, brain structure/function, and body composition. a dna biorepository will also be created.


Eligibility criteria:
inclusion criteria: * children who were enrolled in the domino (donor milk for improved neurodevelopmental outcomes) trial (isrctn35317141).
a study of sph3127 in the treatment of mild to moderate ulcerative colitis

Conditions: Mild to Moderate Ulcerative Colitis

Summary: to preliminarily evaluate the clinical efficacy of the renin inhibitor sph3127 tablets in patients with mild to moderate ulcerative colitis with placebo as a control and determine the recommended dose.


Eligibility criteria:
inclusion criteria: 1. aged 18 - 75 years, male or female; 2. subjects who have been diagnosed with ulcerative colitis； 3. subjects who agree to take effective contraceptive measures with their spouses throughout the study period and for up to 12 weeks after the last dose; 4. subjects who thoroughly learn about the nature, significance, possible benefits, possible inconvenience and potential risks of the trial, understand the study procedures and voluntarily sign the informed consent form prior to their participation in the trial. exclusion criteria: 1. subjects who are diagnosed with crohn's disease or indeterminate colitis; 2. subjects with active infections at screening which may, as evaluated by the investigator, cause increased risks for subjects; 3. subjects who had surgery that might impact the absorption of oral drugs, subjects who will undergo surgery during the study period, subjects who have undergone major surgery before screening, or subjects who have a plan of surgery during the study period; 4. subjects and lactating women and those who will become pregnant within 6 months after the trial starts; 5. subjects with a history of drug abuse with clinical significance within 1 year prior to screening; 6. subjects with other diseases or conditions that the investigator considers unsuitable for this trial.
a study of xstem-vlu in patients with difficult-to-heal venous leg ulcers

Conditions: Venous Leg Ulcer

Summary: the aim of the study is to assess safety, tolerability and preliminary efficacy of xstem-vlu when administered as a single topical dose to patients with difficult-to-heal venous leg ulcers. the study is randomised and the patients will receive either xstem-vlu or vehicle as add on to standard wound care. the patients will be followed weekly for 10 weeks after treatment. at 4 months after treatment, the patients will return to the clinic for an end-of-study visit.


Eligibility criteria:
major inclusion criteria: * written informed consent for participation in the study * male or female patient aged ≥18 years * bmi ≥18.5 and ≥40.0 kg/m2 * lower leg wound due to venous insufficiency * target wound has failed to heal despite standard wound care for a minimum of 6 weeks * a surface area of the target wound of ≥2 and ≤40 cm2 major exclusion criteria: * signs or symptoms of clinically significant ongoing infection i the target wound requiring anti-microbial treatment * history of autoimmune disease, such as but not limited to systemic lupus erythematosus, addison's disease, crohn's disease and type i diabetes mellitus * b-hba1c value ≥52 mmol/mol * plaque psoriasis or any other skin disease that could interfere with the outcome of the study * arterial insufficiency * history of any malignancy within the past 5 years * target wound diagnosed as a malignant wound, neuropathic wound, pressure wound or osteomyelitis * patients who are immunocompromised due to disease or for other reasons such as the use of systemic immunosuppressants
osmolality of oral supplements and ileostomy output

Conditions: Ileostomy - Stoma; Short Bowel Syndrome; Sodium Depletion; Nutritional Deficiency

Summary: this double-blinded, active comparator, cross-over intervention study tested the impact of two different oral supplements on ileostomy output volume and urinary sodium excretion and intestinal aquaporin expression in eight compensated patients with an ileostomy and not on home parenteral nutrition or fluid support.

patients with an ileostomy may experience fluid and electrolyte imbalances sedondary to an unregulated intestinal loss of water and electrolytes. the osmolality of oral supplements may affect these losses. in a double-blinded, active comparator, cross-over intervention study, the investigators test the effects of substituting 800 ml of the usual fluid intake with an intake of either an isoosmolar (300 mosm/kg) or hyperosmolar (700 mosm/kg) supplement during 48 hours, following baseline data collection before both intervention periods. outcome measures were stoma output volume, 24-hour urine and urinary sodium excretion, and intestinal aquaporin 3 and 8 expressions.

Eligibility criteria:
inclusion criteria: * age 18 years or more * ilestomy established 6 weeks or more prior to inclusion * able to drink at least 100 ml fluid per 24 hours * i known inflammatory bowel disease, clinical remission judged by physician's global assessment (pga) * less than 5 kg self-reported weight change during the past 3 months exclusion criteria: * self-reported intolerance to dairy products, including lactose * known renal insufficiency, defined by an egfr less than 30 ml/min * known diabetes mellitus, defined by an hba1c \> 48 mmol/mol (6.5%) * current enteral tube feeding or parenteral fluid or nutrition support more than twice weekly
effects of physical treatment on postural stability in benign paroxysmal positional vertigo (bppv) patients

Conditions: Benign Paroxysmal Positional Vertigo

Summary: the propose of this study is to compare two methods of physical treatment for benign paroxysmal positional vertigo, by evaluating treatment effects on postural stability. the trail design is a double blinded randomized controlled trail, with each patient going through three evaluations: before treatment, 1 week after treatment and 60 days after treatment.


Eligibility criteria:
inclusion criteria: * medical referral for treating "vertigo" * subject has short episodes of rotatory vertigo (up to 1 minute) * subject has positive hallpike-dix test with typical nystagmus * repeated hallpike-dix test will show fatigability exclusion criteria: * hallpike-dix test produces vertigo without nystagmus * subject has bppv of the horizontal or anterior semi-circular canal * subject has other known vestibular or neurologic condition * subject has nystagmus of a different type * subject has a cervical spine problem which prevents the utilization of epley or semont maneuvers * subject is unable to stand for 1 minute * subject gets pharmacologic treatment for vertigo while doing the postural stability evaluation * subject is under 18 years old or a pregnant female or cannot obtain informed concent

Keywords: bppv postural stability epley semont