single shot vs catheter infraclavicular brachial plexus block after distal radius fracture repair

Conditions: Distal Radius Fracture; Post Operative Pain Control

Summary: the purpose of this study is to compare infraclavicular brachial plexus shot single shot block to continuous catheter nerve block done in adult patients who have under gone surgery to repair distal radius fractures. visual analogue scores, opioid consumption, quality of recovery and quality of sleep up to 72 hours post operatively will be used for comparison.

if the patient is willing to participate and signs the consent, he/she will be randomized to one of the two treatment groups: 1. single shot block 2. continuous catheter in the institution investigators usually advocate for regional anesthesia and intravenous sedation for the repair of open fracture of the distal radius. patients will be monitored during block performance with standard asa monitors. all patients will receive 2 l of oxygen via a nasal cannula. sedatives will be titrated to effect. midazolam 1-2 mg, and fentanyl 50-100 mcg will be used for sedation. block time out will be preformed according to standard operating procedure. all blocks will be done under ultrasound guidance. sonosite s nerve machine will be used with a low frequency curvilinear (c5) us probe with 2-5 mhz frequency. both single shot and continuous icb will be performed according to the sop in the department. ultrasound survey of the deltopectoral groove below the clavicle will take place. the axillary artery and the three cords (posterior, medial and lateral) of the brachial plexus will be identified in short axis view deeper to the pectoralis minor muscle. for single shot blocks: a 4 inch 21 gauge single shot (b-braun) needle will be introduced in-plane towards the posterior cord of the brachial plexus and 1-2 ml of dextrose 5% (d5%) bolus will be used to verify correct placement of the needle in the vicinity of the posterior cord and adequate spread pattern to both lateral and medical cord. 20 ml of of ropivicaine 0.5% will be injected through the needle with intermittent aspiration after each 5 ml bolus injection. for the continuous block: a 4 gauge 18 inch tuohy needle ( b -braun) will be introduced towards the posterior cord as above. when the needle tip and the pattern of spread is confirmed using d5% solution, a 21 gauge catheter will be introduced 2 cm beyond the needle tip under ultrasound visualization. the needle will be withdrawn over the catheter. injection of a total of 20 ml of ropivacaine 0.5% ( in divided 5 ml boluses with intermittent aspiration) will take place through the catheter while observing the spread of local anesthetic under ultrasound. the catheter hub will be affixed to the upper lateral chest with sterile occlusive dressings and an anchoring device. block success will be defined as a change in cutaneous sensation to touch with an alcohol pad in the posterior, medial and lateral cord distribution over the forearm and the hand within 30min after injection. subjects with successful catheter placement per protocol and nerve block onset will be retained in the study. subjects with a failed catheter insertion or misplaced catheter indicated by a lack of sensory changes will have their catheter replaced or will be single shot blocked and withdrawn from the study. intraoperative sedation will consist of intermittent boluses of midazolam (1-2 mg), fentanyl (50-100 mcg) and propofol infusion, titrates to sedation and patient comfort (25-50 mcg/kg/min). all patients will receive prophylaxis for postoperative nausea and vomiting (ponv) during surgery. the protocol for prophylaxis against ponv includes administration of 4 mg of dexamethasone after induction of anesthesia and 4 mg of ondansetron 20 minutes before recovery from anesthesia. dexamethasone is withheld if the patient has poorly controlled diabetes mellitus (dm). uncontrolled dm will be defined as random blood glucose above 250 mg/dl.

Eligibility criteria:
inclusion criteria: * patients scheduled for open reduction and internal fixation of a distal radius fracture * american society of anesthesiologists (asa) physical status i -iii * mentally competent and able to give consent for enrollment in the study exclusion criteria: * patient younger than 18 years old * allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone and any of the drugs included in the standard of care * patients opting to go under general anesthesia and those refusing the block * chronic pain syndromes; patients will be defined to have chronic pain if they are using regular daily doses of systemic narcotics for the past 6 months prior to the surgery * bmi of 40 or more

Keywords: infraclavicular brachial plexus block quality of recovery score pain score disability assessment of shoulder and hand questionnaire