surgery and neuroablative procedures in spasticity

Conditions: Upper Extermity Spasticity; Multidisciplinary Approach; Novel Algorithm; Diagnostic Nerve Block; Surgery; Percutaneous Neuroablative Procedures; Refractory Spasticity

Summary: for many patients with spasticity, traditional therapies have not achieved maximal outcomes. due to common complaints such as pain, limb positioning and hygiene concerns, there has been an increase demand for other adjunctive therapies like surgeries and other interventions. this spasticity multidisciplinary clinic consisting of a physiatrist, plastic surgeon and anesthesiologist is performing a novel approach to refractory spasticity to triage and designed a treatment plan for them as routine medical care. this study will document the efficacy of this novel designed multidisciplinary approaches for intervention in complex spasticity patients, and will develop a decision-making algorithm in spasticity including both traditional treatment (i.e. botulinum toxin , bracing) and novel treatments(i.e. neurectomy , cryoneurotomy).

many patients continue to live with disabling spasticity that negatively affects their health, independence and quality of life. for these patients, traditional therapies such as bracing, medications, and botulinum toxin have not achieved maximal outcomes. up to one-quarter of physicians have noted to be limited by the maximal dosage of botulinum toxin allowed in their country. due to common complaints of pain, difficulty with limb positioning, and hygiene concerns there has been an increase in demand for novel adjunctive therapies, including surgery, to improve patient outcomes. the deisgned triage pathway is based on the diagnostic lidocaine nerve block (dnb), which is already using in franco-european studies and has been accepted as academic abstract at the canadian association of physical medicine and rehabilitation annual meeting in gatineau quebec in 2019. in this approach, patients are triaged for intervention based on their responses to dnb, which is applying local anesthesia to a selected nerve branch. also the investigators of this study who have created canada's first interdisciplinary spasticity clinic consisting of a physiatrist, plastic surgeon and anesthesiologist are working to bring the world-leading spasticity interventions to canada and developing canadian techniques. this includes cryoneurotomy and selective microfascicular neurectomy. both of these techniques have been developed in this multidisciplinary clinic and in the past three years and have been published as journal articles, academic posters or presented at international congresses.this research is a pilot study to test the present current triage and treatment pathways. this study will evaluate the patients with upper limb spasticity who are going to have any of traditional treatments (i.e. bracing, botulinum toxin) or novel treatments (i.e. cryoneurotomy, tenotomy, neurotomy) as their standard medical cares. all these assessments are parts of their standard evaluations and the available data will be collected for this study. these data include their range of motions, spasticity grades, upper limb function, pain, satisfaction and injected botulinum toxin dosage. these data will be used to document the efficacy of this approach by comparing these measurements that are already done for their standard clinical care. also, the final result will be helpful to create a canadian algorithm to approach patients with refractory upper limb spasticity.

Eligibility criteria:
inclusion criteria: * adult patient ≥ 18 years old, with upper extremity spasticity causing functional impairment. * patients that have plateaued in outcomes in which the clinical examination suggests further interventions can be trialed. * the clinical examination, including a v1 (maximal passive stretch) and v3 (fast catch) on upper extremity examination that demonstrates further passive or active range may be possible, versus if contracture must be managed. for example, a fisted hand that can be forced open. this includes factors such as fluctuating tone or clonus interfering with the assessment. * the patient undergoes a diagnostic nerve block to determine if there is reducible spasticity in the muscle versus contracture. * the patient has been offered a neuroablative procedure or surgery and has elected to undergo the procedure. the patient has consented to undergo the said procedure. exclusion criteria: * patients where no consent or assent is obtained * unable to attend treatment schedule,