breathing exercises in asthma targeting dysfunctional breathing

Conditions: Dysfunctional Breathing in Asthma

Summary: dyspnoe can disable patients with asthma. dysfunctional breathing (db), resulting in dyspnoe, can mimic or exaggerate asthma. around every forth patient with asthma have db. breathing exercises (brex) can improve asthma-related quality of live (qol) in less severe asthma. no study has investigated the effect of brex on qol neither on level of physical activity in severe asthma. a randomised controlled multicentre trial will include 190 adults with poor asthma control (asthma control questionnaire (acq6)-score≥0.8) from seven outpatient departments and one specialized private clinic. patients will be allocated to either usual care (no intervention) or breathing exercises (brex)-treatment consisting of 12-week intervention including three physiotherapist-sessions focusing on breathing pattern modification (papworth method; buteyko technique) in rest and activity and 10 minutes home-exercise twice daily. primary outcome is change in mini asthma quality of life questionnaire (miniaqlq) at six-months follow-up.

in denmark around 300,000 suffer from asthma. dyspnoe can disable patients with asthma. dysfunctional breathing (db), resulting in dyspnoe, can mimic or exaggerate asthma. around 20-29% of asthmatic patients have db. breathing exercises (brex) can improve asthma-related quality of life (qol) and control of asthma symptoms in less severe asthma. no study has investigated the effect of brex on qol neither on level of physical activity in severe asthma. a randomised controlled multicentre trial will include 190 adults with poor asthma control (asthma control questionnaire (acq6)-score≥0.8) from seven outpatient departments and one specialized private clinic. after optimizing of inhalation technique, patients will be allocated to either usual care (no intervention) or brex-treatment consisting of 12-week intervention including three physiotherapist-sessions focusing on breathing pattern modification (papworth method; buteyko technique) in rest and activity and 10 minutes home-exercise twice daily. primary outcome is change in mini asthma quality of life questionnaire (miniaqlq) at six-months follow-up. secondary outcomes are changes in acq6, nijmegen hyperventilation questionnaire (nq), hospital anxiety and depression scale (had), accelerometry (physical activity level, number of steps), 6 minutes walk distance, and forced expiratory volume in first second (fev1), besides response of global perceived effect rate (gpe) in asthma-related qol and asthma control.

Eligibility criteria:
inclusion criteria: * referred from gp to a secondary, out-patient respiratory clinic for lack of asthma control * pulmonologist-diagnosed asthma * ≥ 2 consultations at a pulmonologist-lead asthma clinic * acq6 ≥0.8 * able to provide written informed consent. exclusion criteria: * trained in breathing exercises by physiotherapist last 6 months * aged \<18 * pregnancy * not able to speak, read or understand danish * any severe disease as judged by the responsible physician * participating in another pulmonary interventional research-project.

Keywords: dysfunctional breathing uncontrolled asthma breathing exercises adults