high and low intensity progressive resisted exercises on pain, range of motion and functional disability

Conditions: Osteo Arthritis Knee; Sarcopenia

Summary: the study will be randomized controlled trial. this study will be conducted in university of lahore teaching hospital, lahore, pakistan. a sample size of 84 will be randomly allocated into two experimental groups, (42 participants in each group), by computer generated random number list. the participants,randomly allocated to the experimental group a, will receive high intensity resisted exercises ,in addition with routine physical therapy as tens (transcutaneous electrical nerve stimulator), hot pack, deep friction massage each session will be of 35-45 minutes with 5 minutes warm up, 35 minutes for training session and lastly 5 minutes for cool down • participants in experimental group b, will receive low intensity resisted exercises in addition with routine physical therapy

recruitment: participants will be recruited and referred by orthopedic doctor, university of lahore teaching hospital to physical therapy department. the study will be randomized controlled trial. this study will be conducted in university of lahore teaching hospital, lahore, pakistan. a sample size of 84 will be randomly allocated into two experimental groups, (42 participants in each group), by computer generated random number list. the participants,randomly allocated to the experimental group a, will receive high intensity resisted exercises ,in addition with routine physical therapy as tens, hot pack, deep friction massage * participants in experimental group b, low intensity resisted exercises in addition with routine physical therapy * both experimental groups will receive sixteen treatment sessions and those will be given over a period of eight weeks (2 sessions per week, each session of 35-45 minutes with 5 minutes warm up and lastly 5 minutes for cool down in both groups. * outcome measure will be taken by assessor at baseline, and at the end of 8th week (at the end of last treatment session) through numeric pain rating scale and koos * randomization and allocation: afterwards, participants confirming the eligibility criteria will be randomly allocated, through computer generated random number list , into two experimental groups (group a, group b). * blindness: study will be single, assessor blinded and an independent investigator will perform randomization and will inform the patients and therapist about the allocation. * intervention: leg presses, knee extension, hip adduction and hip abduction exercises will be performed by patients. there will be a warm up sets for 1 repetition maximum with 2 min gap between both sets (leg press + knee extension exercises) (hip abduction and hip adduction) patients will ask to perform. * duration: sixteen treatment sessions will be given over a period of eight weeks (2 sessions per week, each session of 35-45 minutes). * outcome variables and measures 1. pain (numeric pain rating scale) 2. functional disability (koos) 3. rom (universal goniometer) * outcome measures will be taken at baseline and at the end of last treatment session i.e. 8th week. collected data will be than analyzed.

Eligibility criteria:
inclusion criteria: * both genders. * age range between 35-65 years * diagnosed osteoarthritis patients of grade i to iii according to kellgren \& lawrence on x-ray (diagnosed by orthopedic specialist) * diagnosed patients with sarcopenia according to sarc-f questionnaire. (diagnosed by orthopedic specialist) exclusion criteria: * patients with history of trauma like rta(road traffic accident) , fall history and other loading injuries, patellar fracture or dislocation. * patients with history of surgery (meniscal reconstruction, tkr(total knee replacement) or partial knee replacement etc.) * patients with severe patellofemoral osteoarthritis.

Keywords: osteoarthritis sarcopenia