early pulmonary rehabilitation in exacerbated copd patients

Conditions: Chronic Obstructive Pulmonary Disease

Summary: chronic obstructive pulmonary disease (copd) is characterized by chronic and progressive airflow limitations and subjects with copd also experience exacerbations characterized by the worsening of respiratory symptoms. it's necessary medical intervention, changes in regular medication, and the use of antibiotics and/or corticosteroids followed or not by hospitalization. the exacerbations contribute to worsening of the disease with systemic impairment and muscle weakness is a very relevant event. the physical inactivity, especially related to bed rest, comprises one of the factors contributing to muscle atrophy and loss of muscle strength. thus, the intervention performed during hospitalization is necessary to minimize the consequences which causes impairment in health status subjects. the aim of the study is assess the effect of the intervention with elastic bands, in muscle strength,level of the physical activity, functional capacity, dyspnea on activities of daily living (adl) and quality of life in copd exacerbation subjects. moreover,verify the intervention benefits over 01 and 03 months post exacerbation episode. it will be a prospective, randomized, longitudinal and interventional study. the investigators will be asses both gender patients with exacerbation of copd in 4 situations: first time (at least 24 and at most 48 hours after the beginning of medical therapy); seven days post the first assessment; one and three months post exacerbation episode. it will be assess the muscle strength, physical activity level, functional capacity, dyspnea on adl and quality of life. the patients will be randomized in 2 groups: intervention and control group. the intervention will be performed with elastic bands once a day during seven days. the investigators expected that patients of the intervention group will present better muscle strength, physical activity level and functional capacity than the control group. furthermore, an improvement in dyspnea and quality of life is expected in intervention group when compared as with control group patients. it is hypothesized that the benefits of intervention will be maintained over one month.


Eligibility criteria:
inclusion criteria: * patients aged 40 years or more, of both genders, who are in a an exacerbation of the disease according to global initiative for chronic obstructive lung disease (gold,2015) refered by the doctors, hospitalized or not in exacerbation treatment .all patients should be in spontaneous breathing at the time of assessment, in oxygen use or not and in conditions to understand the proposed evaluations; patients who use non-invasive ventilation will also be included as long as it does not interfere with the protocols; all should agree to participate in the research in a free and informed manner. patients who are referred to the intensive care unit (icu) may be included 24 hours after discharge from the icu. exclusion criteria: * patients who present with orthopedic limitations, other pulmonary diseases, rheumatological, cardiovascular or neurological disorders that not allow the assessment. patients whit drug os alcohol dependence, patients undergoing invasive mechanical ventilation, hemodynamic instability, the presence of unstable angina, will be excluded. in addition, patients with cognitive deficits that impair comprehension of the assessments will be excluded.

Keywords: chronic obstructive pulmonary disease muscle strength physical activity