high-intensity interval training training protocols on cardiorespiratory parameters in patients with type 2 diabetes

Conditions: Diabetes

Summary: aim: to assess whether there are different training effects on glucose concentration and cardiorespiratory parameters of different high-intensity training protocols in patients with type 2 diabetes. type 2 diabetes is a highly prevalent disease associated with cardiovascular disease leading to high levels of mortality, morbidity and health expenditure, characterized by impaired glucose control during activities and reduced aerobic exercise capacity . exercise training is the most effective way to improve compliance, reduce blood glucose concentration and increase insulin sensitivity. training increases muscle capacity, oxidative capacity and glucose transport, peripheral insulin sensitivity is improved. exercise training with high-intensity interval (resting and exercise period) high intensity interval training (hiit) is a form of exercise training that has recently been widely used in the management of type 2 diabetes, including short duration high intensity exercise periods and lower severity or passive rest periods. there are different hiit exercise training programs according to physiological responses in the literature. however, long-term and short-term hiit training training programs were not compared in terms of their effect on glucose concentration and cardiorespiratory fitness. the aim of this study was to compare the effects of different hiit exercise training programs so that exercise programs for patients with type 2 diabetes could be planned more effectively.

this study will be participated patients with type 2 diabetes. patients' laboratory values, pulmonary function test, respiratory muscle strength, exercise capacity, physical activity level, quality of life will be evaluated. pulmonary function test will be assesed with spirometer, respiratory muscle strength will be evaluated with mouth pressure. exercise capacity will be evaluated using six minute walking test, incremental shuttle walk test, cycle ergometer. muscle oxigeneration will be asssed with wearable lactate threshold predicting device. physical activity level will be evaluated trial accelerometer. then, patients will be randomly divided two high intensity interval exercise training groups. first group: short duration high intensity exercise training (exercise load phase : 30sn %100 patients performance, rest phase: 120sn %25 patients performance) second group: long duration high intensity interval exercise training (exercise load phase : 4 dk %100 patients performance, rest phase: 120sn %25 patients performance) all patients will participate three times a week during eight weeks. the muscle oxigeneration, blood glucose consantration, blood pressure, heart rate will be recorded before and after each exercise session. after 8 week, all test will be done again.

Eligibility criteria:
inclusion criteria: * diagnosis of type 2 diabetes * aged 18-64 years * patients can walk and cooperative * body mass index is less than 40 kg / m2 exclusion criteria: individuals have known lung disease,have undergone any cardiac event or surgery within the past six months, have uncontrolled hypertension, and have diabetic complications such as nephropathy, retinopathy and severe neuropathy.

Keywords: diabetes high intensity interval training cardiorespiratory fitness