Kornimate/medical-research-clean huggingface dataset:
antiarrhythmic and cardioprotective effects of atorvastatin versus magnesium sulfate in cardiac valve replacement surgery

Conditions: Arrhythmias

Summary: this study aims to compare the antiarrhythmic and cardioprotective effects of atorvastatin versus magnesium sulfate after cardiac valve replacement surgery

arrhythmia is a common complication after cardiac valve surgery. postoperative atrial fibrillation (poaf) is the most common type of arrhythmia after cardiac surgery. it has different leading causes, including myocardial injury, inadequate myocardial protection, the effect of cardiopulmonary bypass, and electrolyte imbalance. beta blockers, amiodarone, and magnesium sulfate are used for the management of poaf. statin is used commonly for its lipid lowering action, however, some studies shows that statin has powerful pleiotropic effects including its antiarrhythmic effect. this study aims to compare the antiarrhythmic and cardioprotective effects of atorvastatin versus magnesium sulfate after cardiac replacement surgery.

Eligibility criteria:
inclusion criteria: * patients undergoing isolated valvular replacement surgery. * preoperative rhythm: sinus rhythm. * preoperative troponin i \< 0.01 ng/ml. * normal lipid profile. * white blood cells (4-11 x 103/mm3). * preoperative c-reactive protein \< 3 mg/l. exclusion criteria: * history of atrial fibrillation. * any degree of heart block or patients with implanted pacemaker. * prior use of antiarrhythmic drugs. * preoperative lipid lowering therapy (e.g statins) during the last 3 months. * previous treatment with any type of magnesium containing supplementation (the week before the intervention). * underlying heart failure or left ventricular ejection fraction \< 0.3. * previous myocardial infarction. * diabetes or other metabolic disorders. * renal diseases. * hepatic dysfunction. * underlying thyroid problems (hypo/hyperthyroidism). * underlying inflammatory disease (active or controlled) * immunosuppressive and anti-inflammatory medications for the treatment of coexisting conditions. * psychological disorders, * emergency cardiac surgery

Keywords: atorvastatin magnesium sulfate poaf cardiac valve
optic nerve sheath diameter in laparoscopic surgeries during trendelenburg position

Conditions: Colon Disease; Gynecologic Disease

Summary: it is difficult to measure the several levels of intracranial pressure during abdominal surgery, and direct monitoring with intracranial devices is often impossible. measurement of optic nerve sheath diameter (onsd) via ultrasonography has been developed as an alternative method for evaluating intracranial pressure. increased intracranial pressure may cause in expanding of the optic nerve sheath and may increase the diameter. therefore, measuring the diameter of the optic nerve sheath via ultrasonography is considered as a non-invasive, easy-to-apply and reliable method to evaluate intracranial pressure.

the peritoneum is inflated with carbon dioxide (insufflation) and head-down position is performed (trendelenburg) during laparoscopic colon and gynecologic surgeries. intracranial pressure (icp) may be affected by positive intraabdominal pressure due to pneumoperitoneum. the trendelenburg position (usually at a degree of 25-400) causes increasing in the pressure of cerebrospinal fluid during surgery. therefore, cerebral edema and an increasing in icp may occur. it is difficult to measure the several levels of intracranial pressure during abdominal surgery, and direct monitoring with intracranial devices is often impossible. measurement of optic nerve sheath diameter (onsd) via ultrasonography has been developed as an alternative method for evaluating intracranial pressure. the optic nerve is an extension of the central nervous system, surrounded by cerebrospinal fluid (csf) and continues with the nerve sheath. increased intracranial pressure may cause in expanding of the optic nerve sheath and may increase the diameter. therefore, measuring the diameter of the optic nerve sheath via ultrasonography is considered as a non-invasive, easy-to-apply and reliable method to evaluate intracranial pressure. in this study, we aimed to evaluate the changes of optic nerve sheath diameter in patients who will undergo laparoscopic colon and gynecologic surgery during trendelenburg position. our primary goal is to compare the optic nerve sheath diameters via ultrasonography, and our secondary aim is to evaluate the effect of this change on intracranial pressure.

Eligibility criteria:
inclusion criteria: * american society of anesthesiologists (asa) classification i-ii * scheduled for laparoscopic colon and gynecologic surgeries under general anesthesia exclusion criteria: * use of beta blocker or diuretic drugs * severe heart failure * diabetes with ocular or neurologic complications * history of cardiac, eye, intracranial, and thoracic surgery * history of hydrocephalus, glocoma, intracranial tumor, cerebrovascular disease

Keywords: trendelenburg position optic nerve sheath diameter colon surgery gynecologic surgery
frailty index and mortality after a burn surgery

Conditions: Burns; Frailty

Summary: frailty is a condition of a reduced physiological reserve and is associated with postoperative morbidity and mortality. we evaluated the impact of preoperative frailty index (cfi) on 90-day mortality after a burn surgery.


Eligibility criteria:
inclusion criteria: * patients with burn injuries were admitted to the burn icu. exclusion criteria: * patients with incomplete medical records were excluded.
advancing water security: a community participatory school-based hydration intervention

Conditions: Dental Caries; Obesity Prevention

Summary: the goal of this study is to determine the effectiveness and sustainability of a community-participatory hydration intervention over 3 years within a district that has newly installed hydration stations and is operating under a policy designed to enhance heathy hydration practices and promote equitable access to drinking water.

the goal of this study is to determine the effectiveness of a hydration intervention on hydration station usage (primary outcome), body mass index z-scores (zbmi) and dental caries (primary biomedical outcomes), and water bottle usage, beverage selection and intake, and academic outcomes (secondary outcomes).

Eligibility criteria:
inclusion criteria: * lunchroom observations: all students (k-5th \[pre-kindergarten if applicable\]) who eat lunch in the cafeteria on assessment days are eligible * bmi and dental caries assessments: 1) student enrolls in study while in 3rd grade (followed through 5th g) * student surveys: students in 4th-5th grade are eligible to complete surveys assessing beverage intake and perceptions of hydration practices within their school district. * staff surveys: all staff in the target schools will be eligible to complete the personnel survey. exclusion criteria: * lunchroom observations: none. * bmi and dental caries assessments: students are ineligible if they are unable to complete assessments due to developmental or physical reasons, 2) planning to move in the study duration * student surveys: none. * staff surveys: none.

Keywords: hydration water sugar-sweetened beverages dental caries overweight and obesity
covid-19 long-term revalidation follow-up

Conditions: Covid19

Summary: in this monocentric, prospective and descriptive trial we want to evaluate the long-term consequences for patients treated for covid-19. covid patients who were hospitalized for min. 5 days either in a covid-19 department or in intensive care unit will be followed-up for 8 weeks after hospital discharge. this is done via an innovative electronic platform in the home environment (uza@home). on the one hand the quality of life, rehabilitation and reintegration of the patient will be evaluated and on the other hand the patient will be screened for various psychosocial aspects such as anxiety, depression and post-traumatic stress syndrome.


Eligibility criteria:
inclusion criteria: * males and females * adult age * hospitalization with proven covid-19 infection with a minimum stay of 5 days * signed informed consent exclusion criteria: * the patient does not have a smartphone or computer with internet connection.the patient is not sufficiently skilled in entering data via a digital interface. this degree of skill is estimated by the research doctor or nurse. * patient in a palliative setting (dnr 2 or higher outside of covid condition * the patient does not speak the dutch language

Keywords: colonel tele-monitoring
telenursing and breast cancer: the turkish case

Conditions: Breast Cancer Female

Summary: this study aims to determine the effectiveness of telenursing services on chemotherapy symptoms and comfort levels in patients with breast cancer in turkey.

this study aims to determine the effectiveness of telenursing services on chemotherapy symptoms and comfort levels in patients with breast cancer in turkey. the study employs an experimental research methodology with a sample of 96 ambulatory patients (48 experimental, 48 control) who were receiving chemotherapy for breast cancer for the first time in a state hospital. research data were collected by using "patient information form", "edmonton symptom assessment scale", "general comfort questionnaire, "symptoms follow-up form", and "telephone call form". the experimental group received telenursing service every week until the end of the four-cycle chemotherapy treatment, which started one week after the first treatment. the control group did not receive any intervention. investigators analyzed data with spss 15.0 (statistical package for the social sciences) with comparative statistical methods of mannwhitney u test, chi-square test, one way analysis of variance in repeated measurements, and pearson correlation.

Eligibility criteria:
inclusion criteria: * is volunteering to participate in the research, * is 18 years of age or over, * can communicate in turkish, * has turkish literacy skills, * has no hearing, vision problems, and mental disability that may hinder communication, * is female, * has a diagnosis of breast cancer for the first time in her life and consequently receiving chemotherapy treatment in the same protocols for the first time, * did not have a different diagnosis of cancer and related chemotherapy treatment. exclusion criteria: * having been diagnosed with breast cancer before and received chemotherapy treatment accordingly, * having been diagnosed with different cancers before and had chemotherapy treatment related to it, * cancer treatment with oral medications, * refuse to participate in the study * refuse education/counseling * not knowing turkish

Keywords: telenursing breast cancer chemotherapy symptom management
the effects of preoperative immersive and non-immersive virtual reality exposure on dental anxiety in children:a randomised controlled trial

Conditions: Dental Anxiety

Summary: the goal of this randomised controlled trial is to compare the effects of immersive virtual reality(ivre) and non-immersive virtual reality(nivre) andin children having dental anxiety.the main question\[s\] it aims to answer are: 1. is there a significant difference in baseline dental anxiety scores, as measured using the malay-mcdasf and pr across the ivre, nivre, and control groups? 2. what is the mean change score in dental anxiety measured using the malay-mcdasf and pr for ivre, nivre, and control groups after the operative procedure? 3. is there a significant difference in mean change score of dental anxiety measured using the malay-mcdasf and pr across the ivre, nivre, and control groups? 4. is there a significant correlation between the malay-mcdasf scores (subjective) and pr scores (objective) at preoperative, postoperative, and using the score changes for all groups?

participants will be randomised into three groups, immersive virtual reality, non immersive virtual reality and control group.immersive virtual reality group will be asked to play with an immersive virtual reality dental game using virtual reality device preoperatively after which they will undergo treatment. for the non immersive virtual reality participants will be asked to watch a dental cartoon using the virtual reality device passively before treatment and the control group of no intervention, to wait as usual before treatment. all groups will undergo dental treatment of resin based fissure sealant placement under cotton roll isolation in one permanent molar.

Eligibility criteria:
inclusion criteria: * children aged 9-12 years old. * children who can understand and complete the malay-mcdasf questionnaire with a score of 19 and above. * children who requires fissure sealants on sound permanent tooth. exclusion criteria: * children requiring emergency dental treatment for pain, trauma or facial cellulitis. * children that have undergone invasive dental treatment such as extraction and pulp therapy in the past 6 months. * children with hearing or visual impairment, developmental or intellectual disability, cognitive impairment, balance disorders such as vertigo and cybersickness, sensitivity to the motion or flash light, having accident in the eye, face, neck or arms, history of epileptic seizures, history of cardiac problems * parents who refuse to allow their children to participate in the trial.
anesthetic management of patients with chronic sleep disorders

Conditions: Narcolepsy; Idiopathic Hypersomnia; Restless Legs Syndrome

Summary: the aim of this study is to describe and compare the anaesthesia history and possible problems encountered in 3 groups of patients with 3 chronic sleep diseases: narcolepsy, idiopathic hypersomnia, and restless legs syndrome followed at the montpellier sleep unit. for each participant, existing data from the medical record will be used, with their consent. all participants will complete a standardized questionnaire, concerning their history of anaesthesia, the course and possible complications, and questions about their treatment for their sleep disorder.

this is both a retrospective and prospective single-center study. in the prospective part of the study, patients complete a self-questionnaire, with : * a non-specific part, concerning the history of anaesthesia (locoregional or general), the patient's feelings about these anaesthesias (possible difficulties in waking up, pain) and details about the the course of the anaesthesia (including possible complications). * a part specific to the sleep disease (possible rebound of symptoms, management of sleep treatments before and after anesthesia, sleep treatments before and after the different types of anesthesia). evaluation criteria: main: frequency of history of locoregional and general anesthesia, and their possible complications. secondary: frequency of patients with rebound symptoms, or with worsening symptomatology (in each of the 3 groups, and in subgroups of patients with the same treatments), during locoregional and general anesthesia independently. other parameters collected via self-questionnaire (and at the time of the initial evaluation, retrospectively on medical records): * sociodemographic data: age, gender, body mass index * data related to the disease: age of onset of symptoms, age of diagnosis * other associated medical conditions * type of surgery * type, date and the number of anesthesia: locoregional, general

Eligibility criteria:
inclusion criteria: * men and women, more than 16 years old * diagnosed with a chronic sleep disorder including : narcolepsy type 1, type 2, idiopathic hypersomnia, restless legs syndrome (diagnosis according to international criteria, icsd-3, aasm, 2014). * followed at monpellier sleep disorders unit. exclusion criteria: - less than 16 years old at time of the study

Keywords: sleep anesthesia sedation surgery drugs
brief yoga and mindfulness for women who have experienced domestic violence

Conditions: Domestic Violence

Summary: this study aimed to examine the effectiveness of a brief yoga- and mindfulness-based psychoeducation program and its working mechanisms in improving psychological health parameters (depression, anxiety, and stress) among women who have experienced domestic violence (dv). in a randomized controlled trial, 51 dv-victimized women were assigned to an intervention group (n = 27) or a waitlist control group (n = 24). the intervention was a five-week yoga- and mindfulness-based psychoeducation program. the researchers planned to provide support for the effectiveness of a brief yoga- and mindfulness-based psychoeducation program for improving the psychological health of dv-victimized women. self-compassion and rumination were hypothesized as working mechanisms underlying the intervention's success.


Eligibility criteria:
inclusion criteria: * the inclusion criteria for this study required participants to be women aged 18 years or older who had experienced domestic violence in the previous 12 months but were no longer in an ongoing domestic violence situation. additionally, participants needed to have secure access to a smartphone or a laptop / personal computer. exclusion criteria: * refusal to give consent or missing more than one session of the psychoeducation program were the exclusion criteria. the individuals who met the absence criterion were still able to continue the rest of the sessions; however, their questionnaires were not included.

Keywords: brief yoga and mindfulness online psychoeducation self-compassion rumination domestic violence psychological health
coronaphobia in rheumatic diseases

Conditions: Rheumatic Diseases

Summary: covid-19 is a contagious respiratory disease that is caused severe acute respiratory syndrome causing coronavirus-2 (sars-cov-2). the most common symptoms are fever, cough and dyspnoea. patients with rheumatic diseases are at higher risk of infections because of disease activity and immunosuppression. in addition, old age and having concomitant chronic disease are among risk factors for coronavirus. therefore, national health services recommend patients to practice self-isolation and self-quarantine.

covid-19 is a contagious respiratory disease that is caused severe acute respiratory syndrome causing coronavirus-2 (sars-cov-2). it was firstly seen in december 2019 in wuhan, china and spread rapidly all over the world. world health organization (who) was declared covid-19 as a pandemic in march 2020. the most common symptoms are fever, cough and dyspnoea. social isolation and staying home have been suggested to reduce the spreading rate of covid-19 pandemic in many countries. in addition, curfew except necessity was applied in some countries and time of curfew varied by country. therefore, pandemic caused changes in routine life for millions of people. patients with rheumatic diseases are at higher risk of infections because of disease activity and immunosuppression. in addition, old age and having concomitant chronic disease are among risk factors for coronavirus. therefore, national health services recommend patients to practice self-isolation and self-quarantine. however, social isolation was concluded with more increased physical inactivity and sedentary lifestyle. the aim of this study is to investigate coronaphobia in rheumatic diseases and compare with healthy people.

Eligibility criteria:
inclusion criteria: * between the ages of 18 to 65 * have diagnosed with romatoid arthritis, ankylosing spondylitis, systemic lupus erthematosus or fibromyalgia exclusion criteria: * being pregnant * diagnosed with malignancy * had changes of medical treatment in the last 3 months * had dysfunction that limited physical activity such as severe neurological impairment, immobility or cooperation deficits

Keywords: coronaphobia rheumatic diseases covid-19
effects of different doses of vitamin d on cancer-related cognitive impairment in patients with gastrointestinal tumors

Conditions: Gastrointestinal Neoplasms; Cognitive Impairment

Summary: to explore the effect of different doses of vitamin d drugs on gastrointestinal cancer cancer-related cognitive impairment, so as to provide reference and basis for the clinical use of our cognitive function surgery nursing plan for patients with gastrointestinal cancer.

to determine the incidence of postoperative cognitive dysfunction in patients with gastrointestinal tumors to determine the influencing factors of postoperative cognitive dysfunction in patients with gastrointestinal tumors. the characteristics of perioperative cancer-related cognitive impairment in patients with gastrointestinal tumors were analyzed by monitoring preoperative and postoperative fact-cog cognitive scale connection test (hua-shan-version auditory word learning test) dsst digit symbol test gaffes detection task and hematology indexes, such as observation and analysis of the interference pattern of supplement vitamin d preparation postoperative hospital stay in patients with gastrointestinal tumor short-term cognitive impairment related to cancer, in order to reduce the incidence of complications and hospitalization days, improve cognitive function in patients with gastrointestinal tumor surgery, and improve the quality of nursing.

Eligibility criteria:
inclusion criteria: * patients with gastrointestinal tumors diagnosed by gastroscopy and histology and their family members * elective surgery * education level in primary school or above * be able to fill in the questionnaire alone or under the guidance of the researcher * informed consent and voluntary participation in this study exclusion criteria: * patients with cognitive impairment (illiteracy less than 17 points, primary school less than 20 points, secondary school or above less than 24 points) or previous history of cognitive impairment, dementia and delirium confirmed by mmse examination before surgery * patients with life-threatening acute and chronic diseases * patients with eye or ear diseases leading to rapid loss of hearing or vision without aids * patients who have taken drugs related to improving cognitive function or drugs for psychiatric disorders * patients who cannot take care of themselves or are physically disabled and unable to perform neurological function tests * intraoperative hypoxemia (blood oxygen saturation \< 94％) more than 10 minutes * patients who quit or died due to non-cooperation or emergency

Keywords: gastrointestinal neoplasms cognitive impairment vitamin d
evaluation of the cardioblate closure device in facilitating occlusion of the left atrial appendage

Conditions: Left Atrial Appendage Occlusion

Summary: the purpose of this study is to evaluate the performance of the cardioblate closure device to occlude the laa


Eligibility criteria:
inclusion criteria: * subject is greater than or equal to 18 years of age and less than or equal to 80 years of age * concomitant indication for cardiac surgery for one or more of the following:mitral valve repair or replacement, aortic valve repair or replacement, tricuspid valve repair or replacement, cabg (\>=60 years of age), cabg (\< 60 years of age with a history of atrial fibrillation), surgical ablation or maze procedure * the subject is willing and able to provide written informed consent and comply with study requirements * the subject is not contra-indicated for intra-operative transesophageal echocardiogram (tee) exclusion criteria: * thrombus in the laa and/or left atrium * prior laa isolation attempts * subject is unable to take an anticoagulant during the study follow-up period * subject is undergoing an emergency cardiac procedure * life expectancy of less than 12 months * pregnancy or desire to be pregnant within the 12 months of the study procedure

Keywords: left atrial appendage laa atrial fibrillation af