the preventive effects of neurodynamic mobilisation

Conditions: Delayed Onset Muscle Soreness

Summary: in the study, 34 healthy sedentary male volunteers were randomly divided into two groups as nm (n = 17) and sham-nm (n = 17). after the initial evaluation of the individuals, femoral nerve nm and placebo nm techniques were administered three sets a day with ten repetitions for three days a week for three weeks. three days after the end of the applications, the second evaluations were made and the doms creation protocol for the quadriceps femoris (qf) muscle was initiated. in order to trigger doms in individuals, 30 sets and 10 repetitions of eccentric knee extension (35°-95° flexion angles, 30°/sec speed) were performed on the dominant lower extremity with an isokinetic dynamometer. baseline evaluations were repeated immediately after the doms protocol, and at hours 24, 48, and 72. during evaluations, muscle damage (serum creatine kinase (ck), lactate dehydrogenase (ldh), and inflammation (interleukin-6 (il-6), tumor necrosis factor-alpha) biomarkers, pain (activity), pressure pain threshold, and performance (one-leg jump, vertical jump) parameters were measured.

the aim of this study was to investigate the effects of neurodynamic mobilization (nm) technique on muscle damage and inflammation biomarkers, and pain, pressure pain threshold, and functional status in delayed onset muscle soreness (doms). in the study, 34 healthy sedentary male volunteers were randomly divided into two groups as nm (n = 17) and sham-nm (n = 17). after the initial evaluation of the individuals, femoral nerve nm and placebo nm techniques were administered three sets a day with ten repetitions for three days a week for three weeks. three days after the end of the applications, the second evaluations were made and the doms creation protocol for the quadriceps femoris (qf) muscle was initiated. in order to trigger doms in individuals, 30 sets and 10 repetitions of eccentric knee extension (35°-95° flexion angles, 30°/sec speed) were performed on the dominant lower extremity with an isokinetic dynamometer. baseline evaluations were repeated immediately after the doms protocol, and at hours 24, 48, and 72. during evaluations, muscle damage (serum creatine kinase (ck), lactate dehydrogenase (ldh), and inflammation (interleukin-6 (il-6), tumor necrosis factor-alpha) biomarkers, pain (activity), pressure pain threshold, and performance (one-leg jump, vertical jump) parameters were measured.

Eligibility criteria:
inclusion criteria: * being in the age range of 20-32 years. * being male (because gender difference in the magnitude of eccentric exercise-induced muscle damage might exist as shown in previous studies, only men were recruited in the present study.) * being inactive according to activity guidelines published by the american college of sports medicine (less than 30 minutes of moderate physical activity as five times a week). exclusion criteria: * absence of doms symptoms, * history of vascular disease, * recent injury or surgery to their lower extremity, * neurological impairments and regular use of pain and inflammation medications.

Keywords: delayed onset muscle soreness neurodynamic mobilization muscle damage inflammation pain