comparison of patient-reported outcomes for rimegepant and triptans in the 2023 us national health and wellness survey

Conditions: Migraine

Summary: this is a cross-sectional study using the cross-sectional 2023 national health and wellness survey (nhws) data from the us, with a large and nationally representative population (n=75,007). all data from the nhws are reported by respondents, who are recruited through an existing, general-purpose, web-based, consumer panel via opt-in e-mails, co-registration with panel partners, e-newsletter campaigns, banner placements, and affiliate networks. all respondents explicitly agree to be a panel member, register with the panel through a unique e-mail address, and complete an in-depth demographic registration profile. this analysis will focus on respondents who self-report having migraine diagnosed by a physician. individuals who use rimegepant for acute treatment of migraine will be compared with those who use triptans for acute treatment of migraine. outcomes of interest include treatment satisfaction, healthcare resource utilization (hcru), quality of life (qol), work productivity loss, and migraine-specific disability outcomes. inverse probability of treatment weighting (iptw) will be used to adjust for differences that may exist between rimegepant and triptan users prior to comparing outcomes.

this is a cross-sectional study using the cross-sectional 2023 national health and wellness survey (nhws) data from the us, with a large and nationally representative population (n=75,007). all data from the nhws are reported by respondents, who are recruited through an existing, general-purpose, web-based, consumer panel via opt-in e-mails, co-registration with panel partners, e-newsletter campaigns, banner placements, and affiliate networks. all respondents explicitly agree to be a panel member, register with the panel through a unique e-mail address, and complete an in-depth demographic registration profile. this analysis will focus on respondents who self-report having migraine diagnosed by a physician. individuals who use rimegepant for acute treatment of migraine will be compared with those who use triptans for acute treatment of migraine. outcomes of interest include treatment satisfaction, healthcare resource utilization (hcru), quality of life (qol), work productivity loss, and migraine-specific disability outcomes. inverse probability of treatment weighting (iptw) will be used to adjust for differences that may exist between rimegepant and triptan users prior to comparing outcomes. additional information is provided in the study protocol.

Eligibility criteria:
inclusion criteria: * participated in 2023 nhws in the us * consented to the anonymous use of their data for research purpose * aged 18 or older * self-reported a diagnosis of migraine by physician * currently on rimegepant or triptan (via oral route) at the time of the survey exclusion criteria: - currently on both rimegepant and triptans at the time of the survey

Keywords: rimegepant triptans acute treatment of migraine survey cross-sectional design national health and wellness survey (nhws) patient-reported outcomes treatment satisfaction