non-dispensing fitting study comparing the clinical performance hydrogel sphere design contact lenses.

Conditions: Myopia

Summary: the aim of this non-dispensing study is to evaluate the clinical performance of different hydrogel contact lens designs.

this is a 35-subject, double masked, randomized, contra lateral, non-dispensing fitting trial comparing different hydrogel lens materials. for each study, this study will involve 2 visits: lens dispensing (baseline) and 1 hour post lens settling. each subject will be randomized to wear the test and control lenses, in the right or left eye, in a series of four short fitting comparisons as follows: pair 1 (p1): filcon iv i (base curve (bc) 8.6) and ocufilcon d pair 2 (p2): filcon iv i (base curve (bc) 8.7) and ocufilcon d pair 3 (p3): methafilcon a (base curve (bc) 8.6) and ocufilcon d pair 4 (p4): methafilcon a (base curve (bc)8.7) and somofilcon a

Eligibility criteria:
inclusion criteria: a person is eligible for inclusion in the study if he/she: * is between 18 and 40 years of age (inclusive). * has had a self-reported visual exam in the last two years. * is an adapted soft cl (contact lens) wearer. * has a cl spherical prescription between - 1.00 and - 6.00 (inclusive) * has a spectacle cylinder up to 0.75d (diopters) in each eye. * can achieve best corrected spectacle distance visual acuity of 20/25 (0.10 logmar) or better in each eye. * can achieve a distance visual acuity of 20/30 (0.18 logmar) or better in each eye with the study contact lenses. * has clear corneas and no active ocular disease. * has read, understood and signed the information consent letter. * patient contact lens refraction should fit within the available parameters of the study lenses. * is willing to comply with the wear schedule. * is willing to comply with the visit schedule. exclusion criteria: a person will be excluded from the study if he/she: * has never worn contact lenses before. * currently wears rigid gas permeable contact lenses. * has a history of not achieving comfortable cl wear (5 days per week; \> 8 hours/day) * has a cl prescription outside the range of - 1.00 to - 6.00d * has a spectacle cylinder ≥1.00d of cylinder in either eye. * has contact lens best corrected distance vision worse than 20/25 (0.10 logmar) in either eye. * presence of clinically significant (grade 2-4) anterior segment abnormalities. * presence of ocular or systemic disease or need of medications which might interfere with contact lens wear. * slit lamp findings that would contraindicate contact lens wear such as: * pathological dry eye or associated findings * pterygium, pinguecula, or corneal scars within the visual axis * neovascularization \> 0.75 mm in from of the limbus * giant papillary conjunctivitis (gpc) worse than grade 1 * anterior uveitis or iritis (past or present) * seborrheic eczema, seborrheic conjunctivitis * history of corneal ulcers or fungal infections * poor personal hygiene * has a known history of corneal hypoesthesia (reduced corneal sensitivity) * has aphakia, keratoconus or a highly irregular cornea. * has presbyopia or has dependence on spectacles for near work over the contact lenses. * has undergone corneal refractive surgery. * is participating in any other type of eye related clinical or research study.