anterior chamber depth variability between two lenses with different materials

Conditions: Cataract

Summary: compare the change of the anterior chamber depth (acd) variability between the clareon and the acrysof intraocular lens (iol) after implantation over 6 months.

patients undergoing cataract surgery are often otherwise healthy and active with their only restriction being reduced visual quality. within the past few years, intraocular lenses (iols) have been improved to fulfill the needs of these patients. nowadays efforts are aiming for the enhancement of the patient vision and his subjective satisfaction postoperative. one of the best ways to accomplish this is to have a perfect intraocular lens (iol) power calculation. however, the best calculation can't help if the implanted intraocular lens (iol) changes its position after implantation. it should be considered that an anterior chamber depth (acd) shift, decentration, tilt or rotation of an iol could result in a reduction in visual quality. for an aspherical iol, for instance, it is essential not to be decentrated and tilted more than 0.4 mm 2 (0.8 mm 3) and 7° 2 (10° 3), respectively. otherwise it will be outperformed by a spherical iol. the estimation of the post-operative intraocular lens (iol) position and therefore the estimated anterior chamber depth (acd) is presently the main source of error (35% 4 to 42% 5) in iol power calculation and therefore for the refractive outcome of the patients after cataract surgery. presently the pre-operatively measured acd is taken into account for several iol power calculation formulas, such as the haigis formula, the holladay ii formula and the olsen formula. to manage a better outcome an iol with less postoperative influence of the anterior chamber depth (acd) is very important. to accomplish a smaller deviation after the operation of the anterior chamber depth (acd) the haptic and the material of the lens is very important. the change of the anterior chamber depth (acd) after cataract surgery can be easily measured by instruments like the iol-master 700, ac-master and lenstar. it must be considered that every person is different and that change of the anterior chamber depth (acd) in different eyes can cause high measurement errors. the changes in two eyes of the same patient help to minimize the error. these can help to achieve a better outcome for future patients. the hydrophobic acrylate of the acrysof iol has been modified to the new material in the clareon iol. this study will evaluate whether the new clareon has non-inferior axial stability to the acrysof.

Eligibility criteria:
inclusion criteria: * age-related cataract in both eyes * scheduled for bilateral cataract surgery * age 21 and older * written informed consent prior to recruitment * visual acuity \> 0.05 exclusion criteria: * pregnancy (pregnancy test will be taken pre-operatively in women of reproductive age) * any ophthalmic abnormality that could compromise visual function or the measurements * presence of potential zonular weakness such as pseudoexfoliation syndrome, history of ocular trauma, previous ocular surgery.

Keywords: cataract cataract surgery intraocular lens