clinical characteristics and disease burden of diabetic patients based on tianjin regional database

Conditions: Diabetes

Summary: the study aims to investigate the clinical characteristics, treatment, and economic burden of disease of chinese diabetic/non-diabetic patients with/without established cardiovascular disease (cvd), chronic kidney disease (ckd), or at high cardiovascular risk, including: * primary objectives: describe the proportion of chinese diabetic/non-diabetic patients with established cardiovascular disease, ckd, or at high cardiovascular risk including hypertension and hyperlipidemia * secondary objectives: describe the demographic characteristics of the last visit for all patients, and the demographic characteristics of inpatients over time; investigate the clinical characteristic for all patients


Eligibility criteria:
inclusion criteria: * patients in the tianjin regional database from 01/01/2015 to 31/12/2019 * group a: patients with diagnosis of diabetes, and with diagnosis of cardiovascular disease, heart failure, chronic kidney disease or at high cardiovascular risk * group b: patients with diagnosis of diabetes, but not with diagnosis of cardiovascular disease, heart failure, chronic kidney disease or at high cardiovascular risk * group c: patients with diagnosis of cardiovascular disease, heart failure, chronic kidney disease or at high cardiovascular risk, but not with diagnosis of diabetes * group d: patients without diagnosis of cardiovascular disease, heart failure, chronic kidney disease or at high cardiovascular risk, and without diagnosis of diabetes. we will randomly select a group of non-diabetic patients without any of the above diseases by matching on age and gender definition of diabetes, cardiovascular disease, chronic kidney disease and high cardiovascular risk: * diabetes: patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of diabetes (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (international classification of disease (icd)-10 e10-e14); * cardiovascular disease: patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of ischemic heart diseases (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (icd-10 i20\~i25); or patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of cerebrovascular diseases (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (icd-10 i60\~i69); or patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of ischemic peripheral artery disease (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (icd-10 e10.501, e11.603, e14.501, e14.606, e14.503, i73.9, i99.03, i99.04); * heart failure: patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of heart failure (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (icd-10 i50); * chronic kidney disease (ckd): inpatients with at least once 1 discharged diagnosis ckd (icd-10 n18), or inpatients with the last estimated glomerular filtration rate (egfr, calculated by chronic kidney disease epidemiology collaboration (ckd-epi) equation) \<60 ml/min/1.73 m2 or prescription of dialysis, but not with the diagnosis of acute kidney injury (icd-10 n17); or outpatients with at least 2 diagnosis of ckd (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) or with two consecutive egfr (calculated by ckd-epi equation) \<60 ml/min/1.73 m2 by 90 days or more; * high cardiovascular risk: patients with at least 1 discharged diagnosis or 2 outpatient diagnosis of hypertension (the first diagnosis will be the index diagnosis, and the time interval between diagnoses is not restricted) (icd-10 i10\~i15); or at least 1 discharged diagnosis or 2 outpatient diagnosis of hyperlipidemia (icd-10 e78.001-e78.003, e78.101, e78.203, e78.301-e78.304, e78.306, e78.401, e78.501, e78.902); exclusion criteria: * patients with non-chinese nationalities * duplicated storage (records with same inpatient code)