Kornimate/medical-research-clean huggingface dataset:
effect of hamstring muscle length on lunge distance in fencing athletes

Conditions: Athletic Injuries

Summary: the aim of this study was to determine the effect of hamstring muscle length on lunge distance in fencing sword athletes.

the aim of this study was to determine the effect of hamstring muscle length on lunge distance in fencing sword athletes. a goniometer was used to assess hamstring muscle length and a tape measure was used to assess lunge distance in 20 athletes who agreed to participate in the study and signed the consent form. we believe that the results of our study will provide new perspectives on increasing the success of fencing sword athletes and reducing their injuries. spss 24.0 program will be used for statistical analysis. pearson correlation test will be applied to evaluate the relationship between hamstring muscle length and lunge distance.

Eligibility criteria:
inclusion criteria: * being an active licensed fencing athlete in the anatolian archery and fencing club * being an athlete in the sword branch. * being a volunteer to participate in the study * being between the ages of 18-30 exclusion criteria: * having done a strenuous exercise that would affect muscle groups the day before the measurements * having used alcohol and/or any medication the day before the measurements
efficacy of injectable contraceptive and oral contraceptive administered after surgical treatment of endometriosis with pain

Conditions: Endometriosis

Summary: patients with endometriosis-associated pain have conservative surgery performed to remove all visible lesions. then, patients are randomized into two groups. in the first group patients have depot medroxyprogesterone acetate injections every 3 months for a total of 6 months.in the second group patients have oral contraceptive combined pills everyday for 6 months. patients are followed up on recurrence of pain for 1 year after medication.


Eligibility criteria:
inclusion criteria: * premenopausal women from 18 to 45 years of age with endometriosis-associated pain for at least 6 months who had conservative surgery performed. exclusion criteria: * medical therapies for endometriosis other than nsaid within previous 6 months * contraindication to the drugs * wish to conceive * request for extirpative surgery * other pelvic pathology ( adenomyosis, chronic pid, submucous myoma uteri )

Keywords: pelvic pain postoperative medical therapy
chronic otitis media with effusion in chronic sinusitis with polyps

Conditions: Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)

Summary: the relationship between otitis media with effusion (ome) and chronic rhinosinusitis with nasal polyposis (crswnp) remains unclear. a cross-sectional study of 80 consecutively presenting patients who were diagnosed with crswnp was conducted. the aim was to ascertain the prevalence of ome in crswnp patients, to determine whether the severity of crswnp affected ome, and to identify risk factors for ome in crswnp patients.


Eligibility criteria:
inclusion criteria: * patients over 15 years of age * presence of chronic rhinosinusitis with nasal polyposis (crswnp) previously diagnosed or diagnosed at study's onset by endoscopic nasal examination exclusion criteria: * presence of a mucopurulent discharge or granuloma during endoscopic nasal examination

Keywords: otitis media with effusion (ome) prevalence risk factor endoscopic nasal examination otoscopic examination pure-tone audiometry tympanometry
fever and febrile support for parents and carers of children 2016

Conditions: Fever; Febrile Illness

Summary: to assess the suitability and user-friendliness of an information leaflet for parents on management of fever and febrile illness in children. the purpose of the leaflet is to provide evidence-based information for parents regarding fever and febrile illness in children.

the aim of this study is to assess the suitability and user-friendliness of an information leaflet for parents on management of fever and febrile illness in children. the purpose of the leaflet is to provide evidence-based information for parents regarding fever and febrile illness in children. the potential benefit of the leaflet is empowerment parents to take responsibility for monitoring their child's illness, thereby enabling parents to take effective and informed action when required. the investigators hypothesise that provision of a user friendly information leaflet for parents increases knowledge and provides decision support to guide parents fever management. this study will investigate the ability of an information leaflet to increase parental knowledge regarding the management of fever and febrile illness in children. three leaflets were designed. stakeholders were consulted to select the most appropriate leaflet prior to the beginning of the trial. one leaflet will be used in the trial. a prospective, multi-centre, randomized, two-parallel arm, controlled trial with blinded outcome ascertainment will be conducted. three information leaflets were designed based on a previous survey with parents in ireland. one leaflet was selected for use as the intervention following consultation with stakeholders. the primary objective of the project is to quantify if reading and understanding a leaflet on fever and febrile illness management increases parental knowledge on the subject.

Eligibility criteria:
inclusion criteria: * parents with at least one child aged five years of age or younger at the time of recruitment. * parents of healthy children. exclusion criteria: * parents who did not have at least one child aged five years of age or younger at the time of recruitment.

Keywords: fever febrile illness children
fx shoulder solutions retrospective / prospective clinical study

Conditions: Rotator Cuff Syndrome of Shoulder and Allied Disorders; Osteoarthritis Shoulder; Fracture, Shoulder

Summary: subjects implanted with the shoulder replacement medical devices manufactured by fx shoulder solutions and distributed by fx shoulder solutions.

to evaluate patient outcomes following shoulder replacement with fx shoulder solutions medical devices to demonstrate effectiveness, safety and survivorship of fx shoulder solutions medical devices to provide data and analysis to fx shoulder solutions to meet regulatory requirements. to provide data and analysis for presentations, abstracts, publications and other public release of results. clinical data in the investigator's clinic notes and patient files regarding demographics, baseline medical and shoulder status, surgical procedure and implant components, and any completed postoperative clinical data will be collected retrospectively as data for the study following signed patient consent and enrollment into the study. each patient will be evaluated prospectively, and clinical data collected at the first baseline clinical evaluation using the protocol specified evaluations following study enrollment with successive postoperative evaluations in accordance with the postoperative intervals.

Eligibility criteria:
inclusion criteria: * received an fx shoulder solutions replacement medical device in accordance with the indications for use based upon surgeons' determination and standard of care for the selected device system beginning january 1, 2018, through june 30, 2023. exclusion criteria: * patient who does not meet the inclusion criteria above

Keywords: osteoarthritis roartator cuff fracture arthroplasty
prevention of diabetes using mobile-enabled, virtual delivery of the national diabetes prevention program

Conditions: PreDiabetes

Summary: this study will test the weight loss efficacy of a mobile diabetes prevention program intervention. half of the sample of prediabetic adults will receive the virtual dpp and half will receive usual medical care.

there were 84.1 million people with pre-diabetes, 30.3 million people with diagnosed and 7.2 million with undiagnosed diabetes in the united states in 2015, and nearly 2 million are diagnosed with it every year. by 2050, the cdc estimates that 1 in every 3 people globally will have diabetes, a leading cause of death and disability. the primary goal of this study is to evaluate the efficacy of the noom coach diabetes prevention program mobile platform versus usual medical care. the best intervention to date for prediabetes is the centers for disease control and prevention's diabetes prevention program, yet there is limited research investigating a mobile-based delivery of the dpp. pre-diabetes is often discovered during routine medical visitation/annual screening (usual care), but face-to-face time with clinicians is often limited. exploring novel ways, such as mhealth interventions to empower patients to pursue lifestyle change and prevent or delay diabetes onset is critical to addressing the growing diabetes epidemic.

Eligibility criteria:
inclusion criteria: * english-speaking * 18 years of age and older * referral from the patient's physician * hemoglobin a1c: 5.7 - 6.4 within the 3 months prior to enrollment * own a smartphone (apple or android) exclusion criteria: * recent weight loss (by patient report, \>5 lbs in the 6 months preceding enrollment visit) * previous diagnosis of type 1 or type 2 diabetes * serious or persistent mental illnesses * more than 72 hours of hospitalization in the last 30 days * enrollment in a structured weight-loss program currently or within the 1 month preceding study enrollment * pregnant * currently nursing * have given birth within the past 3 months * has been discouraged by a physician to enroll in a dpp program

Keywords: mhealth diabetes prevention program weight loss body weight behavioral interventions
nociception-level (nol) for the assessment of pain in patient unable to self-report

Conditions: Pain; Opioid Use; Dementia; Unconscious; Ventilator Lung

Summary: in this study we aimed to investigate the performance and effectiveness of nol and/or noledge as a tool for pain assessment in geriatric and critical ill non communicating patients. our hypothesis was that nol and the noledge may have good correlation with the health-care professional assessment painad, bps values, even with the use of the drugs affecting autonomic nervous system.


Eligibility criteria:
inclusion criteria: * male and female, age \> 18 years old. * spontaneously breathing or mechanically ventilated * any patient who is unable to express his/her own level of personal pain by using visual scales according to the hospital standard * written informed consent provided by the participant (if they have capacity) or guardian (if they do not have capacity) or a written proxy informed consent from a legally authorized representative empowered to make health-related decisions for the potential study participant. exclusion criteria: * a patient whose staff or research team believes that his or her participation in the research will cause suffering to the patient. * unstable condition preventing planned routine procedures of care, and conditions precluding the use of pmd-200: absence of sinus cardiac rhythm.
effects of immersive virtual reality on balance, mobility, and fatigue in patients with multiple sclerosis

Conditions: Multiple Sclerosis

Summary: gait disorder, imbalance, and fatigue are the most frequently reported complaints in multiple sclerosis (ms), a chronic neurodegenerative disease. the first symptoms in patients with ms are emerging in the age range 20-50 and these patients need long-term rehabilitation. the virtual reality applications developed for these problems which affect the quality of life negatively and cause disability in the following periods may be a good alternative for conventional rehabilitation applications. in this long-term where motivation is important, virtual reality applications in different environments provide patients with the opportunity to do many different tasks amused. in recent years, the vividness has been increased by the 3d virtual reality headsets. the aim of this study is to investigate the effects of immersive virtual reality on the balance, mobility, and fatigue in patients with ms.

the study was designed as a prospective, randomized controlled study. the patients will be randomly assigned to three groups, the "immersive virtual reality (ivr)" group, the "dynamic balance training (dbt)" group and the control group. the trainings will be twice a week for 8 weeks. in the ivr group, firstly 30 minutes of pilates training, 10 minutes of rest and then 20 minutes of virtual reality will be applied. in the dbt group, 20 minutes of dynamic balance exercises will be applied after pilates training. in dynamic balance training, exercises will consist of similar movements required by virtual reality games. the control group will be taught relaxation exercises and will be asked to perform the exercises 2 times for 8 weeks at home. statistical analyses will be performed using the spss software version 15 (spss inc. chicago, il, usa). the pre-training and post-training measurements of groups will be compared with the wilcoxon test. the significance level was set at p\< 0.05.

Eligibility criteria:
inclusion criteria: * participants who are ambulatory and volunteer to participate to the study, in a stable phase of the disease, without relapses in the last 1 month, with an edss between 0-5,5. exclusion criteria: * participants who have orthopedic, vision, hearing, or perception problems * patients who have any cardiovascular or pulmonary disease in which exercise is contraindicated

Keywords: multiple sclerosis virtual reality balance mobility fatigue
effect of follicular flushing in patients with mono-follicular growth undergoing in vitro fertilization

Conditions: Invitro Fertilization; Diminished Ovarian Reserve; Oocyte

Summary: retrieval of an oocyte from a follicle relies on the release of the cumulus-oocyte-complex (coc) from the follicular wall into the lumen, thereby allowing aspiration by a needle. flushing the follicle with multiple aspirations from the same follicle is used as a means to increase the ratio of coc per aspirated follicle. data showed that follicular flushing is not superior to direct aspiration either in normally responding patients or in poor responders undergoing in vitro fertilization (ivf). there is no data in the literature regarding the issue in patients with mono-follicular growth. direct aspiration or repeatedly flushing the follicle for those with a single follicle will be investigated.

oocyte retrieval procedure this study aims to evaluate the effect of follicular flushing during oocyte retrieval procedure in patients with only one follicle. double lumen needle will be used and direct follicular aspiration without flushing will be performed for all patients. if an oocyte will be obtained, the patient will be assigned to group a. if not, at least 1 course of follicular flushing will be used until retrieval of an oocyte and the patient will be assigned to group b.

Eligibility criteria:
inclusion criteria: * women aged 18-40 years * primary infertility * diminished ovarian reserve with single mature follicle on the day of oocyte retrieval exclusion criteria: * natural cycle ivf * presence of endometriosis/endometrioma(s) * absence of cumulus oocyte complex following oocyte retrieval * severe male factor infertility * pre-implantation genetic screening cycles

Keywords: follicular flushing double lumen needle
plantar pressure and electroencephalographic signals during pedal and vision-deprived walking in stroke patients.

Conditions: Stroke

Summary: complex task training may be more effective than simple task training in promoting functional recovery and brain restructuring in stroke participants. the researchers intend to investigate the real-time changes in plantar pressure and electroencephalographic signals in stroke participants during two complex tasks: pedal walking and visual-deprivation walking. the research hypothesis is that pedal walking and visual-deprivation walking can improve the difference of plantar pressure between the affected and unaffected lower limbs of stroke participants, and cause corresponding electroencephalographic changes.

stroke participants perform the following tasks after wearing a plantar pressure device and a 32-lead electroencephalographic cap. first, stroke participants walk on the pedal on the lower limbs of the affected side. then the researchers cover the participants' eyes with an eye mask, the participants perform the task of visual-deprivation walking. finally, the participants walk on a flat surface. each walking task lasts for 60 seconds. the participants can rest for 3-5 minutes between tasks.

Eligibility criteria:
inclusion criteria: * mri or ct diagnosis of the first stroke onset； * the onset of the stroke occurred more than 30 days; * safely walk 50 meters without assistance. exclusion criteria: * cerebellar injury； * brain stem injury； * visual impairment.

Keywords: electroencephalography pedal walking visual deprivation challenging task
effects of 12-week exercises on alexithymia, depression and quality of life in geriatric individuals

Conditions: Depression; Alexithymia; Quality of Life; Physical Inactivity

Summary: the aim of this study is to investigate the effects of aerobic and resistance exercises on depression, alexithymia levels and quality of life of elderly individuals.

in this study, investigators hypothesized that aerobic and resistance exercises can increase the quality of life of elderly individuals by reducing their depression and alexithymia levels. the aim of this study is to investigate the effects of aerobic and resistance exercises on depression, alexithymia levels and quality of life of elderly individuals.

Eligibility criteria:
inclusion criteria: * individuals aged 65 and over who volunteered to participate in the study, * conscious and without communication problems, * no orthopedic injury that prevents walking * those who are physically inactive according to the international physical activity assessment questionnaire * those who have sufficient motivation to participate in the exercise program (will be evaluated by a one-on-one interview by the researchers) * being eligible to participate in an exercise program after a cardiac examination (resting ecg and questioning of cardiac symptoms, advanced tests such as exercise ecg test if necessary) performed by the physician. exclusion criteria: * having a history of neuromuscular disease * serious medical condition (eg advanced malignancy or major neurological, psychiatric or endocrine disease, respiratory failure, etc.) that would prevent the person from participating in exercise training. * less than 1 year life expectancy * having an orthopedic injury that prevents walking * presence of advanced sensory deficit * having visual and hearing problems * not having sufficient communication skills (mini mental test score below 24 points) * not having agreed to participate in the study * uncontrolled hypertension * not being found suitable for exercise in the examination performed by physicians and physiotherapists

Keywords: depression alexithymia quality of life elderly exercise
combined treatment for patients with comorbid substance use disorders and post-traumatic stress disorder (ptsd): an integration of cognitive-behavioral treatment (cbt) and trauma-focused structured writing therapy

Conditions: Substance-Related Disorders; Stress Disorders, Post-Traumatic

Summary: this study is a randomized controlled trial comparing two treatments for patients with comorbid substance use disorder (sud) and post-traumatic stress disorder (ptsd) conducted within two different routine clinical settings for the treatment of sud, namely (a) a day-care and inpatient setting and (b) an outpatient setting. participants will be randomly assigned to either (1) a combination of cognitive-behavioral treatment (cbt) for sud and trauma-focused structured writing therapy, or (2) cbt for sud alone. randomization will take place separately for each setting. it is expected that the combined treatment is significantly more effective in reducing symptoms of sud as well as ptsd than cbt for sud alone. outcome measures will be assessed at pre-treatment, post-treatment as well as 3 months, 6 months and 12 months follow-up.


Eligibility criteria:
inclusion criteria: * diagnosis of substance abuse or substance dependence according to dsm-iv * diagnosis of ptsd according to the dsm-iv or subthreshold ptsd (at least one re-experiencing symptom plus either three avoidance/numbing or two hyperarousal symptoms are present) * 18 years or older * sufficient fluency in dutch or english to complete treatment and research procedures exclusion criteria: * severe psychiatric problems that may interfere with study participation or that require more intensive clinical care than can be offered in the present study (e.g., dementia, psychotic symptoms, depression with suicidal ideation, manic episode and borderline personality disorder) * receiving concurrent psychotherapy * participants using tranquilizers are required to terminate medication use before inclusion * participants using anti-depressant medication are required to stabilize medication use before inclusion.
ambulatory urodynamic evaluation of sacral neuromodulation for non-obstructive urinary retention

Conditions: Acontractile Bladder

Summary: ambulatory urodynamic measurement on patients with diminished or absent bladder contractility before and after trial with sacral neuromodulation therapy.


Eligibility criteria:
inclusion criteria: * patients with diminished or absent bladder contraction exclusion criteria: * prior neuromodulation therapy
perineal versus rectal approach for prostate biopsy to prevent iatrogenic infections

Conditions: Prostate Cancer

Summary: retrospective reports from literature have shown a lower rate of infections for transperineal versus transrectal approach for prostate biopsies in the setting of prostate cancer suspicion. the aim of this study would be to compare in a prospective randomized trial the rate of infection with transperineal versus transrectal approach.

retrospective reports from literature have shown a lower rate of infections for the transperineal versus transrectal approach for prostate biopsies in the setting of prostate cancer suspicion. post-biopsy infection is becoming a more and more challenging situation due to the increase of incidence and development of antibiotic resistant germs. the aim of this study would be to compare in a prospective randomized trial the rate of infection with transperineal vs transrectal approach. patient presenting an indication of prostate biopsy (psa elevation, suspicious lesion at digital rectal, suspicious lesion on mri) would be randomized 1:1 among transrectal vs transperineal biopsies. post-biopsy infection would be monitored by systemic urine analysis at one, two and four weeks after procedure and in case of clinical symptoms.

Eligibility criteria:
inclusion criteria: * indication of prostate biopsy exclusion criteria: * no indication of prostate biopsy * impossibility for prostate biopsy (e.g. major anal stenosis or history of anal amputation) * antibiotic treatment within three months before prostate biopsy

Keywords: prostate biopsy approach transrectal prostate biopsy transperineal prostate biopsy iatrogenic infection prevention