music in reducing anxiety and pain in adult patients undergoing bone marrow biopsy for hematologic cancers or other diseases

Conditions: Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Lymphoproliferative Disorder; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms; Pain; Precancerous Condition; Psychosocial Effects of Cancer and Its Treatment

Summary: rationale: listening to relaxing music during a bone marrow biopsy may be effective in reducing anxiety and pain. purpose: this randomized clinical trial is studying how well music works in reducing anxiety and pain in adult patients undergoing bone marrow biopsy for hematologic cancers or other diseases.

objectives: * determine the feasibility of using music as an intervention to reduce anxiety and perceived pain in adult patients who are undergoing bone marrow biopsy for hematologic cancers or other diseases. * compare differences in state anxiety and perceived pain level between patients treated with or without music intervention. outline: this is a randomized, feasibility study. patients are stratified according to the practitioner performing the procedure. patients are randomized to 1 of 2 treatment arms. * arm i (music intervention): patients complete baseline questionnaires that measure anxiety and anticipated pain prior to bone marrow biopsy (bmb). patients also provide demographic and clinical information, including pre-procedure medications and previous bmb experience. patients then choose from music compact discs with various types of relaxing music (e.g., classical, country, soft rock, and r\&b) and listen to the music through headphones during the bone marrow biopsy for approximately 30 minutes. after the biopsy, patients complete questionnaires that measure their response to the music, in terms of anxiety and perceived pain experienced during the procedure, and their overall level of satisfaction. * arm ii (usual care \[control\]): patients complete pre-procedure questionnaires, as in arm i, and undergo bmb without music intervention. post-procedure questionnaires assess patient response to bmb in the absence of music and their level of satisfaction with the procedure. projected accrual: a total of 60 patients will be accrued for this study.

Eligibility criteria:
disease characteristics: * diagnosis of hematologic malignancy * referred or scheduled for a bone marrow biopsy patient characteristics: * must understand written and spoken english prior concurrent therapy: * prior bone marrow biopsies allowed

Keywords: pain psychosocial effects of cancer and its treatment accelerated phase chronic myelogenous leukemia acute undifferentiated leukemia adult acute myeloid leukemia with 11q23 (mll) abnormalities adult acute myeloid leukemia with inv(16)(p13;q22) adult acute myeloid leukemia with t(15;17)(q22;q12) adult acute myeloid leukemia with t(16;16)(p13;q22) adult acute myeloid leukemia with t(8;21)(q22;q22) atypical chronic myeloid leukemia, bcr-abl1 negative blastic phase chronic myelogenous leukemia chronic eosinophilic leukemia primary myelofibrosis chronic myelomonocytic leukemia chronic neutrophilic leukemia chronic phase chronic myelogenous leukemia de novo myelodysplastic syndromes essential thrombocythemia extramedullary plasmacytoma meningeal chronic myelogenous leukemia myelodysplastic/myeloproliferative neoplasm, unclassifiable polycythemia vera previously treated myelodysplastic syndromes primary systemic amyloidosis progressive hairy cell leukemia, initial treatment prolymphocytic leukemia secondary acute myeloid leukemia secondary myelodysplastic syndromes stage iii adult t-cell leukemia/lymphoma stage iii chronic lymphocytic leukemia stage iii multiple myeloma stage iv adult t-cell leukemia/lymphoma stage iv chronic lymphocytic leukemia relapsing chronic myelogenous leukemia adult acute lymphoblastic leukemia in remission recurrent adult acute lymphoblastic leukemia untreated adult acute lymphoblastic leukemia adult acute myeloid leukemia in remission recurrent adult acute myeloid leukemia untreated adult acute myeloid leukemia mast cell leukemia stage i adult t-cell leukemia/lymphoma stage ii adult t-cell leukemia/lymphoma t-cell large granular lymphocyte leukemia stage i chronic lymphocytic leukemia stage ii chronic lymphocytic leukemia refractory hairy cell leukemia recurrent adult t-cell leukemia/lymphoma refractory chronic lymphocytic leukemia untreated hairy cell leukemia recurrent adult hodgkin lymphoma stage i adult hodgkin lymphoma stage ii adult hodgkin lymphoma stage iii adult hodgkin lymphoma stage iv adult hodgkin lymphoma anaplastic large cell lymphoma angioimmunoblastic t-cell lymphoma recurrent mycosis fungoides/sezary syndrome stage i mycosis fungoides/sezary syndrome stage ii mycosis fungoides/sezary syndrome stage iii mycosis fungoides/sezary syndrome stage iv mycosis fungoides/sezary syndrome recurrent cutaneous t-cell non-hodgkin lymphoma stage i cutaneous t-cell non-hodgkin lymphoma stage ii cutaneous t-cell non-hodgkin lymphoma stage iii cutaneous t-cell non-hodgkin lymphoma stage iv cutaneous t-cell non-hodgkin lymphoma adult grade iii lymphomatoid granulomatosis recurrent adult grade iii lymphomatoid granulomatosis waldenström macroglobulinemia contiguous stage ii adult burkitt lymphoma noncontiguous stage ii adult burkitt lymphoma recurrent adult burkitt lymphoma stage i adult burkitt lymphoma stage iii adult burkitt lymphoma stage iv adult burkitt lymphoma contiguous stage ii adult diffuse large cell lymphoma contiguous stage ii adult diffuse mixed cell lymphoma contiguous stage ii adult diffuse small cleaved cell lymphoma noncontiguous stage ii adult diffuse large cell lymphoma noncontiguous stage ii adult diffuse mixed cell lymphoma noncontiguous stage ii adult diffuse small cleaved cell lymphoma recurrent adult diffuse large cell lymphoma recurrent adult diffuse mixed cell lymphoma recurrent adult diffuse small cleaved cell lymphoma stage i adult diffuse large cell lymphoma stage i adult diffuse mixed cell lymphoma stage i adult diffuse small cleaved cell lymphoma stage iii adult diffuse large cell lymphoma stage iii adult diffuse mixed cell lymphoma stage iii adult diffuse small cleaved cell lymphoma stage iv adult diffuse large cell lymphoma stage iv adult diffuse mixed cell lymphoma stage iv adult diffuse small cleaved cell lymphoma contiguous stage ii adult immunoblastic large cell lymphoma noncontiguous stage ii adult immunoblastic large cell lymphoma recurrent adult immunoblastic large cell lymphoma stage i adult immunoblastic large cell lymphoma stage iii adult immunoblastic large cell lymphoma stage iv adult immunoblastic large cell lymphoma contiguous stage ii adult lymphoblastic lymphoma noncontiguous stage ii adult lymphoblastic lymphoma recurrent adult lymphoblastic lymphoma stage i adult lymphoblastic lymphoma stage iii adult lymphoblastic lymphoma stage iv adult lymphoblastic lymphoma contiguous stage ii grade 1 follicular lymphoma contiguous stage ii grade 2 follicular lymphoma contiguous stage ii grade 3 follicular lymphoma noncontiguous stage ii grade 1 follicular lymphoma noncontiguous stage ii grade 2 follicular lymphoma noncontiguous stage ii grade 3 follicular lymphoma recurrent grade 1 follicular lymphoma recurrent grade 2 follicular lymphoma recurrent grade 3 follicular lymphoma stage i grade 1 follicular lymphoma stage i grade 2 follicular lymphoma stage i grade 3 follicular lymphoma stage iii grade 1 follicular lymphoma stage iii grade 2 follicular lymphoma stage iii grade 3 follicular lymphoma stage iv grade 1 follicular lymphoma stage iv grade 2 follicular lymphoma stage iv grade 3 follicular lymphoma contiguous stage ii mantle cell lymphoma noncontiguous stage ii mantle cell lymphoma recurrent mantle cell lymphoma stage i mantle cell lymphoma stage iii mantle cell lymphoma stage iv mantle cell lymphoma contiguous stage ii marginal zone lymphoma extranodal marginal zone b-cell lymphoma of mucosa-associated lymphoid tissue nodal marginal zone b-cell lymphoma noncontiguous stage ii marginal zone lymphoma recurrent marginal zone lymphoma splenic marginal zone lymphoma stage i marginal zone lymphoma stage iii marginal zone lymphoma stage iv marginal zone lymphoma contiguous stage ii small lymphocytic lymphoma noncontiguous stage ii small lymphocytic lymphoma recurrent small lymphocytic lymphoma stage i small lymphocytic lymphoma stage iii small lymphocytic lymphoma stage iv small lymphocytic lymphoma isolated plasmacytoma of bone monoclonal gammopathy of undetermined significance refractory multiple myeloma stage i multiple myeloma stage ii multiple myeloma post-transplant lymphoproliferative disorder primary central nervous system non-hodgkin lymphoma