evaluating the efficacy and effectiveness of scope - rct

Conditions: Autism Spectrum Disorder; Transition

Summary: the study will entail an evaluation of the feasibility, acceptability, efficacy and effectiveness of scope coach supported internet-delivered psychoeducative program using a randomized controlled design in a clinical health care context. an estimated n=175 will be needed to enable block randomisation according a 2:1:1 ratio to: 1) scope internet-based psychoeducation intervention, 2) self-study controls, who receive eight weekly emails containing informative and relevant websites about autism spectrum disorder (asd), 3) wait-list controls.

the internet-delivered intervention scope was developed using a participatory research approach, i.e. in cooperation with the target group. scope has eight asd theme modules and weekly contact with an experienced clinician (coach) via a message function within the swedish national platform for internet-delivered treatment (1177.se e-services). the three treatment arms means that the self-study controls as well as the wait-list controls will have the option to take part of scope the following semester after having completed the data collection process. the assessment of eligibility is conducted on the national platform for internet-delivered interventions using a web camera application or phone interview. the intake assessment covers depression symptoms and suicidality using madrs-r, functional impairment using whodas 2.0 (who), and validation of autism core symptoms using osu autism and social responsiveness scale. treatment expectancy and satisfaction will be measured using the treatment credibility scale (see outcome measures) and an evaluation of each module.the criteria for feasibility were (1) attrition should be less than 40% and (2) the participants should attend at least 75% of the sessions. efficacy-related measures will be gained through the primary outcome of improved knowledge about asd. secondary outcomes are mental health: symptoms of anxiety and depression; acceptance of diagnosis; and quality of life. in addition, measures of treatment credibility are also completed by the coaches. the measures will be analysed using a series of repeated measures anovas (rmanovas) to analyse differences between treatment arms. the recommended first-line intervention for asd is psychoeducation. psychoeducational interventions for transition-aged autistic youth have a very limited evidence base. therefore, the effect of psychoeducation for the target group is difficult to discern, the current study would contribute significantly to the research field. the findings will be important especially as psychoeducation is a clinically common intervention, provided in a non-standardized way and without sufficient information of its effects. recruitment commenced during the autumn of 2016 and was completed in december 2020. final n=144.

Eligibility criteria:
inclusion criteria: * diagnosed autism spectrum disorder with iq in the average range (\>70) (diagnosed in accordance with the dsm or icd-10 diagnostic manuals) * relevant age group (16 to 25 years) * active participation in the eight-week program * sufficient swedish language proficiency * ability to log on and utilize an internet-based platform exclusion criteria: * current substance misuse (including the past three months) * suicidal ideation, * diagnosed with intellectual disability (according to dsm or icd), * diagnosed with traumatic brain injury (e.g., stroke), * other severe psychiatric disorders (e.g., psychosis) or adverse psychosocial circumstances (e.g., being homeless) that would render participation unlikely or impossible.

Keywords: young adults psychoeducation internet-based intervention adolescents