remineralization potential of prg barrier coat versus fluoride varnish in white spot lesions in permanent anterior teeth of children

Conditions: White Spot Lesion of Tooth; Demineralization

Summary: to evaluate the remineralization potential of prg barrier coat versus fluoride varnish in white spot lesions in permanent anterior teeth of children.

dental caries is a complex disease that is very common among children and is increasing rapidly in low- and middle-income countries. the first sign that the caries process has begun is the appearance of localized areas of enamel demineralization, which manifest as white spot lesions (wsl) with varying degrees of opacity. the approach to managing caries is shifting towards a minimally invasive method, focusing on the prevention, reduction, and reversal of caries in its early stages. by restoring equilibrium between demineralization and remineralization, wsl can be reversed, unlike cavitated carious lesions. the most effective methods for managing and preventing wsls are those based on fluoride. although fluorides have minimal effect on reducing existing wsl, they do prevent the creation of new wsl. their impact is limited to the enamel's outermost 50 μm layer and does not encourage remineralization across the demineralized lesion body. visually, the wsl remains nearly unaltered. recently s-prg filler containing material are available., s-prg fillers have the ability to release and recharge fluoride , s-prg fillers releases al, b, na, si and sr ions silicate and fluoride strongly induce remineralization of the dentin matrix. strontium and fluoride also improve the acid resistance of teeth by converting hydroxyapatite to strontium apatite and fluoroapatite. s-prg fillers become available for use in caries prevention where it is hoped that it would enhance mineralization and reduce acidic attack by oral cariogenic bacteria. according to they concluded that varnish containing 40% of s-prg fillers was more effective than the typical 5% naf-based product and could be used as a substitute for fluoride for the remineralization of initial enamel caries. according to they concluded that s-prg barrier coat has shown better results for treating white spot lesions after one month interval than 5%naf. the unique advantage of prg product (prg barrier coat, shofu) is being light-cured, which serves in facilitating the clinical procedure, offering easier application, and adding excellent self-adhesive properties for durable prolonged protection. to our knowledge there is limited evidence about the clinical performance of prg barrier coat versus fluoride varnish on white spot lesions remineralization in permanent anterior teeth of children therefore comes the importance of our clinical study.

Eligibility criteria:
inclusion criteria: * children aged 8-14 years with good health according to the american society of anesthesiologists (asa-i). * have at least one white spot lesion with international caries detection and assessment system (icdas ii) score one or two * has not used any remineralizing agent in the former three months. * parents who accept to sign informed consent. * cooperative patients exclusion criteria: * patients have caries or restorations in the labial surface. * extrinsic or intrinsic stains. * patients under active orthodontic treatment. * uncooperative patient. * parents refuse to sign informed consent. * medically unfit (other than asai).

Keywords: prg barrier coat white spot lesion fluoride varnish