lifestyle program (scalable nutrition and physical activity) for the improvement of nutrition and physical activity in stage 0-iii breast cancer survivors

Conditions: Anatomic Stage 0 Breast Cancer AJCC v8; Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage IA Breast Cancer AJCC v8; Anatomic Stage IB Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIA Breast Cancer AJCC v8; Anatomic Stage IIB Breast Cancer AJCC v8; Anatomic Stage III Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Anatomic Stage IIIB Breast Cancer AJCC v8; Anatomic Stage IIIC Breast Cancer AJCC v8; Prognostic Stage 0 Breast Cancer AJCC v8; Prognostic Stage I Breast Cancer AJCC v8; Prognostic Stage IA Breast Cancer AJCC v8; Prognostic Stage IB Breast Cancer AJCC v8; Prognostic Stage II Breast Cancer AJCC v8; Prognostic Stage IIA Breast Cancer AJCC v8; Prognostic Stage IIB Breast Cancer AJCC v8; Prognostic Stage III Breast Cancer AJCC v8; Prognostic Stage IIIA Breast Cancer AJCC v8; Prognostic Stage IIIB Breast Cancer AJCC v8; Prognostic Stage IIIC Breast Cancer AJCC v8

Summary: the purpose of this phase ii trial is to identify the most effective dose level (number of classes) of a diet and physical activity lifestyle program based on how well it improves diet and physical activity in stage 0-iii breast cancer survivors. study results may provide researchers with information on how to best implement diet and physical activity recommendations among breast cancer survivors.

outline: participants are randomized to 1 of 2 arms. arm a (low dose): participants attend one diet and physical activity class delivered remotely via zoom and receive an ehealth communication intervention for 6 months. arm b (high dose): participants attend 12 twice monthly diet and physical activity online sessions delivered remotely via zoom and receive an ehealth communication intervention for 6 months.

Eligibility criteria:
inclusion criteria: * previous diagnosis of stage 0-iii breast cancer in the past 10 years at the time of enrollment * no evidence of recurrent or metastatic disease * no uncontrolled diabetes mellitus defined as glycosylated hemoglobin (hgb a1c) \> 8% * no uncontrolled hypertension per seattle cancer care alliance (scca) standard of care * at least 60 days post final chemotherapy, biologic therapy, or radiation therapy and/or surgery. current use of endocrine therapy is permitted (e.g., tamoxifen and aromatase inhibitors) * access to phone for study contacts * access to smartphone, tablet, or computer and internet to attend online session(s) and receive study electronic ehealth communication (text messages and access to website) * willing and able to attend the online session(s) on saturdays, or via online accessed videos, for up to 12 sessions in 6 months * successfully complete all run-in activities, including at-home and over the phone assessments, 7 days of collecting physical activity data via accelerometer, and providing blood and stool sample * willing and able to complete all study activities for 6 months after randomization * participants must consume \< 5 servings of fruits and vegetables per day and/or engage in \< 150 minutes per week of moderate to vigorous physical activity, as assessed by brief questionnaires * participants must have an eastern cooperative oncology group (ecog) scale of performance status score of 0 or 1 for performance status. * signed physician approval for diet change and physical activity * able to understand and willing to sign written informed electronic (e) consent in english exclusion criteria: * participants must not be active smokers within the past 30 days. * women must not be pregnant at time of enrollment

Keywords: breast cancer survivors diet ehealth nutrition physical activity breast