Kornimate/medical-research-clean huggingface dataset:
sport climbing with parkinson's disease

Conditions: Parkinson Disease

Summary: this controlled interventional study will investigate the effects of a 12-weeks sport climbing course compared to 24 weeks of unsupervised physical exercise on motor symptoms in parkinson's disease

the primary aim of this study is to evaluate the effects of a 12-week sport climbing course versus unsupervised physical exercise on motor symptoms in patients with parkinson's disease. background: sport climbing (sc) is known as a whole-body workout, which additionally trains cognitive, mental, and social abilities. in contrast to its public image, sc in a controlled environment using "top-rope" belay, is a safe sport and can be performed at any age and at any level. in the field of neurological rehabilitation, it is already used as "therapeutic sc" for other neurological diseases, such as stroke, multiple sclerosis, depressions etc. but studies on climbing in pd patients are lacking. hypothesis: to find significant improvement of motor symptoms in the climbing group compared to the control group as well as biopsychosocial improvements after 6 weeks, 12 weeks, and 6 months after the intervention. methods: effects of sc on motor symptoms in 48 pd patients in total, who will be randomized into a climbing group (n=24) and a control group (n=24) will be evaluated. the climbing group will follow a 12-week 90 min/week climbing trainings course, led by professional climbing instructors. the control group will receive education/information material of the european physiotherapy guidelines for physical activity recommended by the who and will be instructed to follow the recommendation of the guidelines to independently live an active lifestyle and train unsupervised. all patients will be evaluated with clinical assessments at baseline, in between the study period (mid), after completing the 12-weeks study period (post). as additional outcomes, health benefits of sc in pd with a holistic approach, covering biopsychosocial aspects will be investigated. therefore, non-motoric and motoric parameters will be evaluated, and follow-up assessments 6 months after.

Eligibility criteria:
inclusion criteria: * idiopathic parkinson's disease * hy stage 1-3 exclusion criteria: * cognitive impairment * severe hearing or visual impairment * severe orthopedic problems

Keywords: parkinson's disease sport climbing motor symptoms training therapy
retrospective analysis of speech performance using the hires ultra and hires ultra 3d cochlear implant

Conditions: Cochlear Hearing Loss

Summary: this is a retrospective study designed to collect speech perception results for hires ultra ci and hires ultra 3d ci users as measured in the clinical routine and to confirm the performance of these devices.


Eligibility criteria:
inclusion criteria: * unilateral or bilateral hires ultra ci or hires ultra 3d ci users including * ultra version v2 newly implanted on this side (group 1) * ultra version v2 users implanted following an ultra version v1 device failure in the same ear (group 2) * informed consent signed exclusion criteria: * no exclusion criteria
psychiatric comorbidity and quality of life in patients with obsessive compulsive disorder(case control study )

Conditions: Obsessive-Compulsive Disorder

Summary: psychiatric comorbidity and quality of life in patients with obsessive compulsive disorder(case control study )

obsessive-compulsive disorder (ocd) is a mental and behavioral disorder\[7\] in which a person has certain thoughts repeatedly (called "obsessions") and/or feels the need to perform certain routines repeatedly (called "compulsions") to an extent that generates distress or impairs general functioning.\[1\]\[2\] the person is unable to control either the thoughts or activities for more than a short period of time.\[1\] common compulsions include excessive hand washing, the counting of things, and checking to see if a door is locked.\[1\] these activities occur to such a degree that the person's daily life is negatively affected,\[1\] often taking up more than an hour a day.\[2\] most adults realize that the behaviors do not make sense.\[1\] the condition is associated with tics, anxiety disorder, and an increased risk of suicide.\[2\]\[3\] the cause is unknown.\[1\] there appear to be some genetic components, with both identical twins more often affected than both non-identical twins.\[2\] risk factors include a history of child abuse or other stress-inducing event.\[2\] some cases have been documented to occur following infections.\[2\] the diagnosis is based on the symptoms and requires ruling out other drug-related or medical causes.\[2\] rating scales such as the yale-brown obsessive compulsive scale (y-bocs) can be used to assess the severity.\[8\] other disorders with similar symptoms include anxiety disorder, major depressive disorder, eating disorders, tic disorders, and obsessive-compulsive personality disorder.\[2\] treatment may involve psychotherapy, such as cognitive behavioral therapy (cbt), and antidepressants, such as selective serotonin reuptake inhibitors (ssris) or clomipramine.\[4\]\[5\] cbt for ocd involves increasing exposure to fears and obsessions while preventing the compulsive behavior that would normally accompany the obsessions.\[4\] contrary to this, metacognitive therapy encourages the ritual behaviors in order to alter the relationship to one's thoughts about them.\[9\] while clomipramine appears to work as well as do ssris, it has greater side effects and thus is typically reserved as a second-line treatment.\[4\] atypical antipsychotics may be useful when used in addition to an ssri in treatment-resistant cases but are also associated with an increased risk of side effects.\[5\]\[10\] without treatment, the condition often lasts decades.\[2\]

Eligibility criteria:
inclusion criteria: * 1. both sex 2. age groups : 18 : 60 are included 3. accept to participate in the study exclusion criteria: - 1. presence of major neurological disease as head trauma and sensory or motor defect as blindness or deafness 2. active psychiatric disordes 3. patients refuse to participate in the study
critical shoulder angle and acromial index on 3d models

Conditions: Shoulder Injuries; Rotator Cuff Tears; Rotator Cuff Injuries

Summary: objective: the relationship between rotator cuff tears and morphological features of the shoulder joint has not been fully explained. the earlier studies are usually done with two-dimensional radiography images, but joint positions and bone formations could not be fully evaluated in two-dimensional images. this study aims to evaluate the relationship between rotator cuff tears and critical shoulder angle (csa) and acromial index (ai) values in three dimensions. methods: this study examined computerized tomography of 24 rotator cuff tears (rotator cuff tear group) and 20 bankart lesions, and no rotator cuff tears (control group). csa and ai were measured on three-dimensional glenohumeral joint models obtained by three-dimensional reconstructions of computed tomography examinations. the investigators anticipate results of this study will guide clinicians in revealing the etiology of rotator cuff degeneration and determining the surgical method to be used for treatment.


Eligibility criteria:
inclusion criteria: * a total of 44 patients, including 24 patients with proven rotator cuff tear by arthroscopic surgery (rotator cuff tear group) and 20 patients with proven bankart lesion and no rotator cuff tear by arthroscopic surgery (control group), were included in the study. exclusion criteria: * those with an inflammatory disease and trauma history were not included in the study.
effect of no added salt diet on urinary sodium and blood pressure

Conditions: Hypertension

Summary: there is much evidence that a reduction in dietary salt intake lowers blood pressure in hypertensive individuals, however few have looked at effect of 'no added salt diet' and modest salt intake on total restriction of sodium intake with especial attention to very exact surrogate of urinary sodium excretion. our study demonstrates that a modest reduction in salt intake from regular level of 10 - 12 g per day to the recommended level of 5 - 6 g per day lowers blood pressure by 12.1/ 6.8 mmhg at day time and 11.1/5.9 mmhg at night time.however only 35% of patients reach to the goal of sodium restriction of diet(below 100 meq/dl in 24 hours urine.it means even modest salt restriction can dramatically decrease blood pressure with no added salt diet.

abstract incidence of hypertension as a major cardiovascular treat is increasing. the best known diet for hypertensives is 'no added salt diet'. in this study we evaluated the effect of 'no added salt diet' on hypertensive population with high dietary sodium intake by measuring 24 hour urinary sodium excretion. method \& results: in this single center randomized study 80 patients (60 cases and 20 controls) not on any drug therapy for hypertension with mild to moderate hypertension were enrolled. 24 hour holter monitoring of bp and 24 hour urinary sodium excretion were measured before and after 6 weeks of 'no added salt diet'. there is no statistically significant difference between age , weight , sex , hyperlipidemia , family history of hypertension , mean systolic \& diastolic bp at day and night and mean urinary sodium excretion in 24 hour urine of case \&control groups .78% of all patients had moderate to high salt intake . after 6 week of 'no added salt diet' systolic \& diastolic bp significantly decreased at day (mean decrease: 12.1 /6.8 mmhg) and night (mean decrease: 11.1/5.9 mmhg ) which is statistically significant between case \& control groups (p 0.0001). urinary sodium excretion of 24 hour urine decreased 37.1meq/d ± 39,67mg/dl which is statistically significant in case \& control groups (p: 0.0001). only 36% of patients after no added salt diet reach to pretreatment goal of 24 hour urinary sodium excretion of below 100meq/dl (p:0.001). conclusion: despite modest effect on dietary sodium restriction, no added salt diet significantly decreases systolic \& diastolic bp and should be advised to every hypertensive patients. trial registration research deputy-smums84-2384 key words: blood pressure, no added salt diet, urinary sodium

Eligibility criteria:
inclusion criteria: * hypertension proved by 24 hours holter monitoring * mild to moderate hypertension * signing the written consent exclusion criteria: * use of any drug for hypertension * use of any drug for 6 week period * unable to collect 24 hours urine * unable to tolerate 24 hours holter of blood pressure

Keywords: blood pressure no added salt diet urinary sodium
tom: testosterone in older men with sarcopenia

Conditions: Sarcopenia; Hypogonadism; Muscular Diseases

Summary: the purpose of this study is to determine whether testosterone replacement in older men with low testosterone levels will increase muscle strength, improve physical performance and overall sense of well being, and reduce fatigue.

the primary objective of this study is to determine whether testosterone replacement in older men, who have low testosterone levels and mild to moderate physical impairment, will increase their maximal voluntary muscle strength of major upper and lower extremity muscle groups. the second objective is to determine whether testosterone replacement will improve the power of knee extension, physical performance tests, the level of physical activity (measured by 3d accelerometer), self-reported disability, exercise tolerance and mobility. the third objective is to determine whether testosterone supplementation improves fatigue, affect, and overall sense of well being in older men with low testosterone levels. a fourth objective is to define the minimum clinically important differences in physical measures perceived by the participants (mcid). participant involvement will require 15-17 clinic visits over 28 weeks. five to 7 of these visits are for physical testing, including body composition, muscle performance, and physical function. throughout the study, hormone measurements will be obtained.

Eligibility criteria:
inclusion criteria: * community dwelling, ages 65 and older * self-reported difficulty in climbing 10 steps without resting, or difficulty in walking 2 or 3 blocks outside on level ground * a score of 4 to 9 on the short physical performance battery (mild to moderate physical impairment) * total serum testosterone level (tt) \ 100 ng/dl * without dementia (mini-mental state examination \[mmse\] score \> 24) exclusion criteria: * use of testosterone, anabolic steroids, dehydroepiandrosterone (dhea), androstenedione or recombinant growth hormone (rgh) in the past year * alcohol or drug abuse * use of anti-convulsants or glucocorticoids (equivalent to prednisone \> 20 mg/day) * prostate cancer, breast cancer or other cancers with life expectancy \< 5 years * limiting neuromuscular, joint or bone disease, or history of stroke with residual neurological problems * any neurological condition that would impact cognitive functioning including: * epilepsy * multiple sclerosis * hiv * parkinson's disease * stroke * other focal lesion * diagnostic and statistical manual of mental disorders, fourth edition (dsm-iv) axis i psychiatric disorder in past year or use of psychotropic medications in 6 months * abnormal prostate examination; psa \> 4 ng/ml; or bph symptom score \> 21 * unstable angina, new york (ny) class iii or iv congestive heart failure or myocardial infarction within 3 months of entry * abnormal laboratory values (at discretion of principal investigator) * untreated thyroid disease; systolic blood pressure \> 160 or diastolic \> 100 mm hg * body mass index \> 40 kg/m2 * untreated severe obstructive sleep apnea

Keywords: andropause frailty hormone replacement therapy aging
radiofrequency treatments for lumbar facet joint pain management

Conditions: Low Back Pain; Zygapophyseal Joint Arthritis

Summary: in this study, investigators compared the effectiveness of medial branch conventional radiofrequency application and combined radiofrequency application in patients with lumbar facet joint disease , focusing on pain scores. the combined radiofrequency application, a sequence of pulsed radiofrequency and conventional radiofrequency , has been shown to be successful in treating neck pain and headache. these findings are of significant importance in the field of pain management and spinal disorders.

the treatment of chronic pain using pulsed radiofrequency (rf) has not shown any significant side effects. as a result, a combined approach of using both pulsed and conventional rf treatment in the same session has been assumed since the 2010s. this combined rf method is still widely used for pain management. the aim of this study is to compare the effectiveness of conventional rf with the combined rf method as a medial branch rf method for the management of lumbar facet joint pain.the study involved patients who had undergone medial branch denervation for lumbar facet joint pain and had medical records available. this study was conducted retrospectively by examining the study data. patients with missing data were excluded from the study. patients underwent a fluoroscopy-guided selective medial branch nerve block using 2% lidocaine 0.5ml before treatment. after 30 minutes, they were asked if there was a 50% reduction in pain intensity.the conventional rf group consists of patients who received medial branch rf with a duration of 2 minutes, at 80̊ c temperature, and 7 volts. in the combined rf group, treatment was initiated first with a conventional rf duration of 2 minutes at a temperature of 80̊ c at 7 volts. then, pulsed rf duration was applied for 6 minutes at a temperature of 42 c at 45 volts, with a pulse frequency of 2 hz and a width of 20 ms.after procedure in the outpatient clinic, experienced pain specialists recorded nrs (numeric rating scale) and dn4 (douleur neuropathic 4 questions) scores at the 6th and 12th-month follow-up appointments after the procedure.

Eligibility criteria:
inclusion criteria: * 40 - 90 years of age * patients with low back pain for more than three months and did not respond to conservative treatment exclusion criteria: * patients who underwent facet joint medial branch rf treatment previously * patients had additional interventional pain treatment or lumbar surgery within one year of the procedure * patients had radicular and significant disc pathology, psychiatric diseases or mental problems, malignancies * patients of one year follow-up could not be assessed entirely in the system

Keywords: pulsed radiofrequency treatment radiofrequency ablation
turkish validation of the geriatric pain measure - short form

Conditions: Geriatric Assessment; Pain Measurement; Chronic Pain

Summary: this study aims to adapt, validate, and assess the reliability of the geriatric pain measure - short form in turkish. a total of 150 patients aged 65 years and older will complete the scale under the supervision of pain management and gerontology specialists. reliability and validity will be evaluated using statistical analyses, including internal consistency, test-retest reliability, and correlation with validated pain and sleep scales. ethical approval has been obtained, and all participants will provide informed consent.

for the turkish adaptation, validation, and reliability study of the geriatric pain measure - short form, permission was obtained from dr. eva blozik, the original developer of the scale. the adaptation process will follow standard cross-cultural validation guidelines, including forward translation into turkish by an expert group, back-translation into english by a separate expert group, and comparison of the back-translated version with the original english version for conceptual and linguistic accuracy. a multidisciplinary expert panel, including turkish language specialists and pain management experts, will review the final turkish version, making necessary cultural adaptations to ensure semantic equivalence. the study will involve 150 patients aged 65 years and older visiting the pain management clinic, where they will complete the turkish version of the scale under the supervision of pain management and gerontology specialists. reliability will be assessed through internal consistency (cronbach's alpha), test-retest reliability, and item-total correlations, while construct validity will be evaluated using factor analysis. concurrent validity will be examined by correlating the turkish version of the scale with other outcome measures. ethical approval has been obtained from başakşehir çam and sakura city hospital ethics committee, and all participants will provide written informed consent before participation.

Eligibility criteria:
inclusion criteria: * geriatric patients with chronic pain * patients who agreed to participate in the study exclusion criteria: * demantia * mental of physical disorders that effect patients answering the scales * diagnosis of malignancy

Keywords: geriatric assessment pain measurement chronic pain geriatric pain measurement short form
title: effect of therapeutic touch on daytime sleepiness, stress and fatigue

Conditions: Stress; Fatigue; Sleepiness

Summary: objective: this study was conducted to assess the effect of therapeutic touch on stress, daytime sleepiness, sleep quality and fatigue among the students of nursing and midwifery. design: randomized placebo-controlled study.

the trial was conducted between april and july 2018. the students who met the inclusion criteria were separated into three groups through randomization method as in therapeutic touch (n=32), placebo (n=32) and control (n=32), and a total of 96 students participated in the study. in this randomized placebo controlled study, the therapeutic touch group were subjected to therapeutic touch for twice a week throughout 4 weeks with each session of 20 minutes. the data was acquired via student information form, epworth sleepiness scale, pittburgh sleep quality index, perceived stress scale and visual analogue scale for fatigue.

Eligibility criteria:
inclusion criteria: * students who were at and above the age of 18, * were the 1st year, 2nd year, 3rd year or 4th year students of nursing or midwifery, * did not receive any energy therapy (reiki, healing touch, therapeutic touch), * received a score above 10 from the epworth sleepiness scale (ess), * did not have any communication problem, * and accepted to take part in the study were included in the study. exclusion criteria: * students who were getting a psychologic and/or pharmacologic treatment in regard to their sleep, fatigue and stress problems, * previously got a psychiatric diagnosis, still had a psychiatric illness, * previously or still used anxiety (psychotropic) medicines were excluded from the study.

Keywords: therapeutic touch daytime sleepiness sleep quality stress fatigue nurse-midwifery student
gait retraining to reduce knee osteoarthritis pain

Conditions: Osteoarthritis, Knee

Summary: the purpose of this study is to determine how well people can be trained to produce new and different movements through the use of haptic feedback. one particular application is retraining individuals to walk differently in order to reduce knee joint loads to prevent or treat knee osteoarthritis as an alternative to surgical treatments.

during the movement retraining session, you be given different combinations of haptic, visual, and auditory feedback in order to inform you on desired movement changes. this will take place at the human performance laboratory at stanford university. motion analysis will be done while you perform movement activities (such as locomotion). prior to performing these movement tasks the investigators will attach reflective markers to your body using tape, pre-wrap and/or ace bandages. the investigators will record motion of your body's movements using infrared cameras which capture anatomical data from the reflective markers on your body. the investigators will provide you with feedback to inform you of desired movement modifications. haptic feedback devices such as vibration motors and skin stretch devices will be attached to your body via velcro straps and will be used to give "touch" feedback. there will be a computer monitor in front of you during testing to provide visual feedback. sounds will be played using speakers near the testing area to provide auditory feedback. the time needed for set up and performance of the above set of tests is approximately 90 minutes. you will be performing walking and other movements for only a small part of that time. the rest of the time will be spent preparing you for the experiment. after the investigators examine your movement data, if some of the data appear inaccurate or the investigators are unable to process the data, the investigators may ask you to repeat the movement analysis at a later time.

Eligibility criteria:
inclusion criteria: * symptoms of medial compartment pain during the previous 6 weeks * radiographic evidence (ap x-ray) of medial compartment knee osteoarthritis (kl score of 3 or less) * ability to walk unaided for 25 minutes without rest * age \> 18 exclusion criteria: * bmi \> 30 * previous injury or surgery on foot, ankle, knee, hip, or back inhibiting ability to adopt different walking gait * use of shoe insert or hinged knee brace * corticosteroid injection within the previous 6 weeks * age \> 80