evaluation of upper extremity functions in obesity hypoventilation syndrome patients

Conditions: Obesity Hypoventilation Syndrome (OHS)

Summary: obesity hypoventilation syndrome (ohs) is a disease characterized by daytime hypercapnia and sleep-related respiratory disturbances in individuals with a body mass index (bmi) greater than 30 kg/m², without any other condition that could lead to hypoventilation. although various mechanisms play a role in the pathogenesis of ohs, the most significant one is the altered respiratory system mechanics due to obesity. obesity also leads to a decrease in peripheral muscle strength and exercise capacity. it has been reported that in obese individuals, not only general body movements and lower extremities but also upper extremity movements are negatively affected. specifically, it has been observed that during activities against gravity, movement speed is low while the duration of movement is high. in ohs patients, daily living activities, physical activity, and exercise capacity are also negatively impacted. supported or unsupported arm movements are of great importance in performing daily living activities. the muscles activated during both simple arm lifting and combined movements also function as accessory respiratory muscles. in individuals with cardiopulmonary diseases, an increase in the respiratory workload, especially during unsupported arm movements, has been observed. it is thought that in ohs patients, both the effects of obesity and the respiratory system may limit upper extremity functions. however, no studies have evaluated upper extremity functions in these individuals. therefore, the aim of investigators study is to evaluate upper extremity functions in ohs patients.

the study will include patients diagnosed with obesity hypoventilation syndrome, who are followed at the department of chest diseases, istanbul university faculty of medicine. the study will be conducted in accordance with the helsinki declaration, and an informed consent form will be obtained from the participants who are willing to take part in the study. before the study begins, the participants will be informed about the purpose of the study and provided with all relevant details. participants who agree to participate will be invited to the chest diseases department of istanbul university faculty of medicine. demographic information of the participants will be recorded, followed by the evaluation of body composition, upper extremity functional exercise capacity, grip strength, and activities of daily living. the main aim of the study is to comprehensively investigate the upper extremity functions in patients with ohs.

Eligibility criteria:
inclusion criteria: * individuals between the ages of 18-65 * individuals diagnosed with ohs by a chest disease specialist exclusion criteria: * individuals with neurological or orthopedic problems that prevent them from performing the tests or understanding the scales applied within the scope of the study * additional pulmonary disease * uncontrolled cardiovascular disease * presence of uncontrolled diabetes

Keywords: obesity hypoventilation syndrome (ohs) upper extremity function hand grip strength activities of daily living