clinical study of rhythmic auditory stimulation for gait disorders

Conditions: Hemiplegia Due to Stroke; Parkinson Disease; Parkinsonian Syndrome

Summary: the aim of this clinical trial was to determine whether rhythmic auditory stimulation is effective in treating gait disorders in patients with post-stroke hemiplegia, primary parkinson's disease, and various parkinsonism syndromes. the main questions it aims to answer are: does rhythmic auditory stimulation increase walking speed in patients with gait disorders? to determine whether rhythmic auditory stimulation is effective in treating gait disorders, researchers will compare a gait rhythmometer with an active control that does not receive rhythmic stimulation. participants will: gait training was conducted once a day for 15 minutes for 7 consecutive days resting-state functional magnetic resonance imaging (fmri) was performed before and after treatment feedback on subjective improvement at the end of the 7-day treatment


Eligibility criteria:
for post-stroke hemiplegia inclusion criteria : * age 50-80 years old * one or more strokes (cerebral infarction or cerebral hemorrhage), with the most recent stroke occurring at least 6 months earlier * walking independently without a cane or walking aid with obvious gait asymmetry * 0.4m/s\< baseline velocity \<0.8m/s * sufficient hearing, vision and comprehension to complete motor function tests * patients were willing and able to participate in all study procedures and signed informed consent * no other rehabilitation treatment was received at present exclusion criteria: * unable to cooperate with the motor function test * uncontrolled hypertension * myocardial infarction within the past 3 months * with bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc. * except for stroke, there was no parkinsonism, myasthenia gravis, poliomyelitis and other nervous system diseases affecting the walking function of patients. for primary parkinson's disease (pd) inclusion criteria: * age 50-80 years old * pd met the diagnostic criteria of chinese diagnostic criteria for parkinson's disease (2016 edition) * obvious panic gait, freezing gait or slow gait, but can walk independently without the use of a cane or walking aid * hoehn-yahr (h-y) stage 2-4 * 0.4m/s\< baseline velocity \<0.8m/s * sufficient hearing, vision and comprehension to complete motor function tests * patients were willing and able to participate in all study procedures and signed informed consent * no other rehabilitation treatment was received at present exclusion criteria: * unable to cooperate with the motor function test * uncontrolled hypertension * myocardial infarction within the past 3 months * with bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc * there was no stroke, myasthenia gravis, poliomyelitis and other neurological diseases affecting the walking function except for primary parkinson's disease for parkinsonism syndrome: inclusion criteria: * age 50-80 years old * all parkinsonism syndrome except primary parkinson's disease, including but not limited to drug-induced parkinsonism, multiple system atrophy, cerebral small vessel disease-related parkinsonism, etc * obvious panic gait, freezing gait or slow gait, but can walk independently without the use of a cane or walking aid * 0.4m/s\< baseline velocity \<0.8m/s * sufficient hearing, vision and comprehension to complete motor function tests * be willing and able to participate in all study procedures and sign informed consent * no other rehabilitation treatment was received at present. exclusion criteria: * unable to cooperate with the motor function test * uncontrolled hypertension * myocardial infarction within the past 3 months * with bone and joint diseases, such as a history of lower limb fracture within 1 year, waist and lower limb bone and joint surgery, bone and joint deformity seriously affecting walking, etc * there was no stroke, myasthenia gravis, poliomyelitis and other neurological diseases that affected the walking function except for parkinsonism

Keywords: rhythmic auditory stimulation hemiplegia after stroke parkinsonism syndrome gait disorders parkinson disease