bronchoscopy versus imaging in diagnosis of airway diseases in critically ill children

Conditions: Airway Disease

Summary: patients with suspected airway illness often go through a diagnostic assessment that includes chest radiographs, computed tomography scans, and fiber optic bronchoscopy.

a correct diagnosis is necessary for effective therapy of airway illness. usually necessary for these invasive treatments. the "gold standard" for tracheobronchial pathology identification and diagnosis is rigid or fiber optic bronchoscopy. fiber optic is a procedure that is generally safe, although it can have negative effects, particularly in patients who are at greater risk. therefore, it is important to continually develop and improve non-invasive procedures that enable airway examination. the laryngotracheal and bronchial airway is affected by a wide range of diseases, and imaging is essential for assessing these anomalies. the location, scope, and type of these lesions may be determined with great accuracy using computed tomography. bronchoscopy allows direct visualization of trachea and bronchi by rigid open tube bronchoscope or flexible fiber optic scope. detailed evaluation of airways with bronchoscopy offers advantages over other diagnostic tools and allows interventional procedures such as biopsy of lesions, removal of foreign bodies, dilatations of stenosis and obtaining samples for cytological and microbiologic analysis. bronchoscopy can be performed either by rigid or flexible instruments depending on the needs of patients. the pediatric airway is notably different from adults. it is smaller in size, larynx and tracheal proportion is more as compared to adults and epiglottis is more posterior and narrower . fiber optic bronchoscopy with or without bronchoalveolar lavage is particularly important in the diagnosis and treatment of specific respiratory problems in critically ill infants and children hospitalized in the pediatric intensive care unit.these comprise situations such as segmental lung collapse, pulmonary infections including community-acquired and ventilator-associated pneumonia, pulmonary infections in immunocompromised hosts, and pulmonary bleeding. in addition, bronchscopy has a special role in airway problems in very sick pediatric patients. it may be crucial in intubation of the difficult airways and in the assessment of airway anomalies. there are various indications for bronchoscopy: persistent stridor , congenital, anatomical, or acquired anomalies, persistent wheezing, hemoptysis, persistent or recurring atelectasis, persistent or recurring pneumonia, and localized hyperinflation. other uses of bronchoscopy are bronchoalveolar lavage , getting biopsy samples, and aspiration of secretions. examples of therapeutic bronchoscopy are administering medications and removing foreign bodies. absolute contraindications for bronchoscopy include severe hypoxemia, hemodynamic instability, and uncorrected hemorrhagic diathesis. severe pulmonary hypertension and congenital cyanotic cardiomyopathy with increased bronchial collateral circulation are relative contraindications. in addition, instabilities in the cervical spine or atlanto occipital transition are considered relative contraindications for rigid bronchoscopy. the common complication of bronchoscopy is related to anesthesia, mechanical trauma ( epistaxis , pneumothorax, and hemoptysis), hypoxemia, laryngospasm, post-lavage fever, and infection.

Eligibility criteria:
inclusion criteria: * age 1 month: 18 years. * critically ill patients with suspected airway diseases for the following indications: * difficult intubation. * extubation failure (defined as the replacement of an endotracheal tube within \<48 h after extubation). * persistent stridor. •acute unexplained respiratory distress.• localized hyperinflation. * suspected foreign body. * persistent and recurrent wheezes. * persistent and recurrent atelectasis. * unexplained hemoptysis exclusion criteria: * age ( \ 18 years ) * severe hypoxemia * hemodynamic instability * uncorrected bleeding diathesis * unresolved lung infection