Kornimate/medical-research-clean huggingface dataset:
physical and functional recovery from cardiac surgery in hospitalized patients: a feasibility pilot study

Conditions: Coronary Artery Disease; Mitral Valve Insufficiency; Aortic Valve Stenosis; Aortic Valve Regurgitation; Mitral Valve Stenosis; Coronary Artery Bypass Graft Triple Vessel

Summary: ambulation following surgery has been found to be beneficial for patients; however, nurses and doctors struggle with getting post-operative, hospitalized patients to walk on their own. one promising strategy to address this might be an ambulation orderly, an employee whose single responsibility is to assure that patients walk 3-4 times per day. however, the effect of the ambulation orderly on post-operative physical activity has not yet been described. it is important to quantify what the ambulation orderly does in order to assess if this is an effective method for helping patients walk. as a result, the investigators will perform a pilot randomized controlled trial to test the effects of an ambulation orderly in patients hospitalized with recent cardiac surgery. half of the patients will be assigned to walk with the ambulation orderly 3-4 times/day and the control group will be given standard nursing encouragement and assistance and encouragement to walk. the investigators will evaluate the average total daily step counts (over the hospital course, usually 4-7 days) and the change in walking distance between a baseline and a final 6 minute walk test. the investigators will also evaluate exercise physiologic parameters (heart rate, oxygen saturation) during ambulation, patient functional independence, and patient satisfaction.

the investigators will perform a prospective randomized controlled trial at baystate medical center, a 684-bed academic teaching hospital that serves as the referral center for a population of approximately 800,000 people living in western massachusetts. the responsibility of the ambulation orderly is to walk patients after having a cardiac surgery, such as a coronary artery bypass surgery or a valve replacement or repair. patients will be randomized to receive visits from the ambulation orderly (ambulation group) or to receive the standard care of baystate medical center (control group). the standard of care will be nurse-directed ambulation, as is currently done in all other nursing floors at baystate medical center. nurses will be instructed to walk with the patients as they did before the initiation of the ambulation orderly and as they do when the orderly is on vacation, at conferences, training, or away for illness.

Eligibility criteria:
inclusion criteria: * patients who have had a cardiac surgery procedure (coronary artery bypass grafting surgery or valve surgery). must be ambulatory prior to surgery exclusion criteria: * unable to consent, cognitively impaired, and patients unable to walk prior to surgery

Keywords: ambulation cardiac rehabilitation
mortality risk prediction tool in hospitalized dementia patients

Conditions: Dementia

Summary: the objective of this study is to develop and validate a clinical prediction tool to estimate 1-year mortality among hospitalized patients with dementia.

patients with dementia are frequently hospitalized. despite having specialist palliative care needs, they have infrequent and late access to corresponding services. accurate and personalized predictions of mortality risk among hospitalized patients with dementia could inform clinical care decisions made during admission and upon discharge, including whether or not to engage specialist palliative care services. existing prognostic tools have limitations. we seek to develop and validate a clinical prediction tool to estimate 1-year mortality in this patient population. the derivation cohort will comprise about 235,000 patients with dementia, who were admitted to a hospital in ontario from april 1st, 2009 to december 31st, 2017. predictor variables have been fully prespecified based on a literature review and on subject-matter expertise, and were categorized as follows: sociodemographic factors, comorbidities, previous interventions, cognitive status, functional status, nutritional status, admission information, and previous health care utilization. the outcome variable will be mortality within 1 year of admission, which will be modelled as a binary variable, such that a logistic regression model will be estimated. predictor and outcome variables will be derived from linked population-based administrative databases. the validation cohort will comprise about 63,000 dementia patients, who were admitted to a hospital in ontario from january 1st, 2018 to march 31st, 2019. model performance, measured by predictive ability, discrimination, and calibration, will be assessed in the validation cohort. the final model will be based on the full cohort.

Eligibility criteria:
inclusion criteria: * diagnosis of dementia using a validated algorithm to identify cases based on a combination of hospital codes, physician claims, and prescribed medications that are specific to dementia * hospitalization at least once from march 31st, 2009, to april 1st, 2019 exclusion criteria: * age \<65 years at the time of index admission * ineligibility for universal health insurance at the time of admission

Keywords: prediction model prognosis
impact of chatgpt-based nursing process training

Conditions: Nurse-Patient Relations

Summary: the goal of this randomized controlled study is to determine the impact of chatgpt based nursing process training on nursing students' clinical decision-making competencies and artificial intelligence anxiety. population and sample: the population of the research consists of senior students studying at gülhane faculty of nursing, university of health sciences. power analysis was performed to determine the number of people to be included in the study. the power of the test was calculated with the g\*power 3.1 program. in a similar study in the relevant literature, the effect size regarding the change in clinical decision-making level was calculated as 0.898. in order to exceed the 99% value in determining the power of the study; at the 5% significance level and 0.898 effect size, 44 people, 22 people in the groups, need to be reached (df=21; t=1.721). in the research, it was aimed to reach a total of 60 people, 30 people in the groups, considering the high power of the test and the losses.

nurses, who are important members of the healthcare team, often encounter situations in the clinic that require them to make decisions. nurses need to make a complex evaluation by using critical thinking and problem-solving skills in clinical decision-making.during nursing education, it is aimed at helping students acquire the skills to make this complex evaluation. to gain these skills, real-life experiences during clinical practices, case discussions, simulations, and skill laboratories can be used. it is thought that artificial intelligence applications, which have been increasingly used in recent years, can contribute to the development of clinical decision-making skills in nursing education. in this regard, this study aimed to investigate the effect of chatgpt use training in the nursing process on nursing students' clinical decision-making competencies and artificial intelligence anxiety.

Eligibility criteria:
inclusion criteria: 1. being a senior student at the faculty of nursing in the 2023-2024 academic year 2. agreeing to participate in the research exclusion criteria: 1. having previously received chatgpt training 2. withdrawing from the research voluntarily 3. incompletely filled forms

Keywords: artificial intelligence students, nursing
a randomised, assessor-blind, comparative efficacy clinical trial of 3 pediculicides.

Conditions: Pediculosis

Summary: objective to compare the cure rates (defined as the complete absence of live lice, adults or nymphs, as diagnosed by wet-combing of three australian approved head lice products for the treatment of primary school children with head lice infestation. the study design will be randomised and assessor-blind using three comparative parallel treatment groups. the study population will consist of queensland state primary school children (up to year 7) with live head lice (adults or nymphs) on the hair or scalp who have not used any head lice product in the four weeks prior to the study.

all products were used according to the manufacturer's instructions. kp24 and banlice were applied twice separated by a one week interval. moov head lice treatment was applied on day 0, day 7 and day 14. the cure rate (absence of live lice) one day after the first administration for all products was a secondary outcome measure. the cure rate at 7 days after the final administration (day 14 for banlice or kp24 and at day 21 for moov head lice treatment) was the primary outcome measure. siblings were treated if these were found to be infected as an enrolment criteria.

Eligibility criteria:
inclusion criteria: * male or female primary school children. * presence of live head lice (adults or nymphs) on the hair or scalp. the presence of live lice will be determined from a visual inspection of the hair and scalp and dry-combing of the hair. combing will stop immediately once live lice are observed. the presence of lice eggs alone is not a sufficient condition for inclusion in the trial. * be available for the duration of the trial. * parent / guardian is willing not to use other head lice products or methods (e.g. combs) to treat their child's head lice for 21 days after the first treatment. * parent / guardian has given written informed consent to their child's participation in the trial. exclusion criteria: * history of allergies or adverse reactions to head lice products or the components of the specific products being tested. * treatment with any head lice product in the month prior to day 0. * presence of scalp disease(s). * if a subject has a sibling in grade 1-7 this sibling must also be enrolled in the study and treated on day 0 otherwise the subject must be considered ineligible for enrolment. * subjects must have one fixed place of residence

Keywords: pediculus capitis lice
a pilot study of constraint induced movement therapy in preschool cerebral palsy after botulism toxin injection

Conditions: Cerebral Palsy, Spastic; Rehabilitation

Summary: to establish a pilot randomized, crossover study on applying 2 constraint-induced movement therapy (cimt) interventions in children with hemiplegic cerebral palsy after botulinum toxin injection during preschool education.

this study was designed to be a pilot study on the use of 4-week 2-hours/day and 2-week 4-hours/day cimt interventions in children with hemiplegic cp after a bont-a injection in preschool education, and compared the effects and psychological stress of cp children relative to the 2 cimt programs.

Eligibility criteria:
inclusion criteria: hemiplegic or quadriplegic cp children were under a regular rehabilitation program with bont-a injections. they were classified as gross motor function classification system level i and ii, aged between 3 and 6 years old, with at least below average mentality, and were in mainstream preschool education; the extension of their hemiplegic wrist and metaphalangeal joint was greater than 10 degrees. exclusion criteria: children were excluded if they (a) could not understand or cooperate with the cimt program, (b) had joint contracture of an upper limb, and (c) could not actively extend their hemiplegic wrist.

Keywords: cerebral palsy constraint-induced movement therapy botulinum toxin rehabilitation occupational therapy
integrated prevention of hiv risk and intimate partner violence among adolescents in south africa

Conditions: Sexual Behavior; Intimate Partner Violence

Summary: the purpose of this study is to test the feasibility and acceptability of safe south africa, an integrated intervention for preventing hiv and intimate partner violence perpetration for male adolescents 15-17 years of age.

this study will investigate the acceptability and feasibility of safe south africa, an integrated intervention to prevent adolescent behavioral risk for human immunodeficiency virus (hiv) and perpetration of intimate partner violence (ipv). safe south africa is a theory-driven, developmentally-tailored and gender-specific intervention designed for male adolescents 15-17 years of age. the research will be conducted in south africa, a country with the largest hiv epidemic and some of the highest rates of ipv perpetration in the world. preventive interventions are urgently needed during adolescence when risk for human immunodeficiency virus (hiv) and intimate partner violence (ipv) increases exponentially. yet, few behavioral interventions integrate hiv-ipv prevention and are tailored for the unique age and developmental needs of adolescents. we will investigate the acceptability and feasibility of safe south africa with three study aims: (1) a development aim - this aim will result in the creation of safe south africa, an integrated male adolescent preventive intervention for hiv risk behavior and ipv perpetration; (2) an acceptability aim - this aim will consist of an evaluation of the social ecology of hiv and ipv risk with a survey of n=100 of adolescents, and a test of the acceptability of safe south africa through an open pilot trial with n=20 male adolescents; and (3) a feasibility aim - this aim will consist of a randomized controlled pilot trial with 1- and 6-month follow-up in a sample of n=60 male adolescents to assess the feasibility and acceptability for a future fully powered randomized controlled trial to evaluate efficacy of the intervention.

Eligibility criteria:
inclusion criteria: * male adolescent * 15-17 years of age, inclusive of 15 and 17 exclusion criteria: * parent/guardian does not provide consent * adolescent does not provide assent
self-rehabilitation at home after lumbar arthrodesis (sahara)

Conditions: Spondylolisthesis, Lumbar Region

Summary: lumbar arthrodesis is more and more common in general population. patients need early reeducation after surgery but do not always have access to a physiotherapist. the investigators aim to study the benefits of self-rehabilitation at home after lumbar arthrodesis, showing amelioration in lumbar pain and in quality of life for concerned patients. for this, the investigators designed a randomized-controlled study to test if self-rehabilitation at home right after surgery is superior than rehabilitation done by a physiotherapist 4 to 6 weeks after surgery (standard treatment for our patients).

due to population aging, lumbar arthrodesis is becoming more frequent in general population. at the same time, those patients need early rehabilitation, even if they do not experiment any motor disability after surgery : it has been showed that early rehabilitation improves lumbar pain thanks to muscle strengthening. the design of the study is prospective,monocentric, controlled and randomized. this study compares progressive self-rehabilitation at home after lumbar arthrodesis, explained to the patient by a physiotherapist during his or her stay at the hospital and started right after surgery, versus rehabilitation done by a physiotherapist 4 to 6 weeks after surgery (standard treatment). the primary outcome is decrease of lumbar pain at 6 weeks and 3 months after surgery. the secondary outcomes are improvement of functional abilities and improvement of pelvis and limbs ranges of motion. patients of both groups will be followed by surgeon and physiotherapist at 6 weeks and 3 months.

Eligibility criteria:
inclusion criteria: * lumbar pain and/or nerve root pain and/or limp without any motor deficiency of the limbs, before and/or after surgery (if any motor deficiency occurs after surgery, it will be a secondary exclusion criteria) * surgery for posterolateral lumbar arthrodesis, from a degenerative etiology, from 1 to 3 lumbar levels (one level means one inter-somatic space) * surgery indication after optimal medical treatment, including appropriate pain medicine, and fail of medical treatment for reducing lumbar pain and/or nerve root pain and/or limp * return home possible after surgery * after signing consent during pre-operative visit with the surgeon exclusion criteria: * people under 18 years-old * pregnant or breast-feeding women * psychiatric and/or neurodegenerative comorbidity * motor deficiency of the limbs before and/or after surgery * iliac extension of arthrodesis * any postoperative complication lengthening stay at hospital * medical contraindication for early rehabilitation
early usage of bakri ballon in managing postpartum hemorrhage

Conditions: Postpartum Hemorrhage

Summary: postpartum hemorrhage (pph) is the top reason for maternal deaths in china. the four major causes of pph include uterine atony, genital tract laceration, placenta factors and systemic medical disorders (including inherited and acquired coagulopathy). management of pph contains the application of uterotonic agents, using hemostasis agents, transfusion of blood component products, conservative procedures (intrauterine packing or balloon tamponade, compression sutures, vascular ligation and uterine artery embolization using sponges), and even hysterectomy. the bakri balloon has attained its efficacy and popularity ever since it was invented by doctor yn. bakri. although it is recommended by many countries as a routine procedure for pph management, the bakri balloon is not yet a first choice in china due to lack in clinical data of preventive usage. the aim of this study is to prove the efficacy and safety of the bakri balloon in early management of pph.

data of 472 patients from 20 different hospitals had a bakri balloon tamponade. enrolled patients would follow the next process: assessment of blood loss intrapartum and 2 hours postpartum; laying the bakri balloon; assessment of blood loss, uterine contraction and complications after bakri balloon tamponade; further conservative surgical measures (uterine placation (b-lynch suture), arterial embolization; artery ligation; cervical cerclage) or even hysterectomy if necessary; recording the puerperium infection and involution of uterus. data were analyzed by spss 20.0 database. the results were expressed as mean ± standard deviations or median with interquartile range. differences between groups were assessed by student's unpaired t test, mann-whitney u test, or chi-square test as appropriate. correlation analysis was performed using the spearman rank correlation method. to identify independent relationships and adjust the effects of covariates, multiple linear regression analyses were performed. p values of \<0.05 were considered significant.

Eligibility criteria:
inclusion criteria: * women with vaginal or cesarean delivery; * pph caused by: uterine atony, placenta factors, coagulation disorders, hematological disorders, hepatic diseases, obstetric dic; * not reacting well to continuous uterine massage or uterotonic agents including oxytocin (0.04iu/l ivgtt to a maximum of 60iu), hemabate (250-500ug im) and duratocin (100ug iv); * without other conservative surgical treatment(uterine compression suture, internal arterial embolism; vascular ligation); * signing the informed consents; exclusion criteria: * has undergone or will undergo conservative surgical treatment(uterine compression suture, international arterial embolism; artery ligation); * impaired soft birth canal injury; * untreated uterine deformity; * definite indication for uterectomy.

Keywords: pph, bakri ballon
validation of the masimo invsensor00063 in febrile and afebrile subejcts

Conditions: Fever

Summary: this is a prospective, non-randomized data collection study to evaluate the performance of the masimo invsensor00063 in obtaining temperature measurements.

individual sites are only representative of a subset of the overall population, per iso 80601-2-56:2017(medical electrical equipment - part 2-56: particular requirements for basic safety and essential performance of clinical thermometers for body temperature measurement), and therefore clinical bias and limits of agreement should not be evaluated for the subsets. publication of results should include repeatability from individual sites and the combined clinical bias and limits of agreement (nct05787782, nct05674344 and nct05779397).

Eligibility criteria:
inclusion criteria: * participant age ≥ 1 year * afebrile or febrile at time of enrollment: for febrile subjects, ≥ 99.5 f/ 37.5 c for sublingual temperature reference; ≥ 100.4 f/ 38 c for temporal artery temperature reference. * english-or spanish-speaking patient or parent/legal guardian exclusion criteria: * participants deemed not suitable for the study at the discretion of the investigator
effect of pilates training on cognitive functions in patients with stroke

Conditions: Stroke

Summary: the purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke

stroke remains a primary cause of morbidity throughout the world mainly because of its effect on cognition. individuals can recover from physical disability resulting from stroke, but might be unable to return to their previous occupations or independent life because of cognitive impairments. post-stroke cognitive impairment is not a unitary syndrome but incorporates a variety of deficits in multiple domains such as attention, executive functions , memory, language and visuoperceptual abilities. cognitive impairment occurs in up to 64% of people who have had a stroke and has been associated with a 3-fold increase in risk for mortality, institutionalization and decreased instrumental activities of daily living function. pilates training was developed by joseph h. pilates .it belong to a group of so-called body-mind exercises, where the focus is on controlled movement, posture, and breathing .pilates (pronounced: puh-lah-teez) improves mental and physical well-being , increases flexibility through controlled movements done as mat exercises. pilates training improve cognitive functions through increasing blood and oxygen flow to the brain , support neuronal survival in the developping brain ,generate new neurons ,provides mood enhancement ,increases neurotransmitters and neurotrophins assure the survival of neurons in areas responsible for learning, memory and higher thinking.

Eligibility criteria:
inclusion criteria: 1. forty patients with stroke (hemiparesis) with muscle power at least grade 3 according to manual muscle testing scale (appendix vi) from both genders their ages will be ranged from 50-65years old. 2. patients with ischaemic stroke in the domain of the carotid system. 3. all patients have mild cognitive deficits in domains ( memory, attention, orientation, perception and executive skills) with score \<25 according to montreal cognitive assessment (appendix iv). 4. duration of illness not less than six months and not more than 18 months. 5. spastcity grade (1) according to the modified aschworth scale (mas) ( bohannon and smith, 1987)(appendix iii). 6. all patients in the study should be ambulant independently. 7. medically and psychologically stable patients. 8. all patients will approve and sign a consent form (appendix i). 9. all patients are litrate. exclusion criteria: 1. patients with hemiparesis with motor weakness or incoordination. 2. patients with cardiovascular problems (uncontrolled hypertension ,unstable angina ,significant coronary heart disease and or congestive heart failure). 3. patients with dementia with score \<3 according to mini cog test(appendix v). . 4. patients with musculoskeletal problems (deformity or contracture). 5. medically unstable and uncooperative patients. 6. patients with moderate and severe obesity (bmi≥ 35 kg/m2). 7. patients with depression with score \> 8 according to hamilton depression rating scale (ham-d) (appendix vii).