Kornimate/medical-research-clean huggingface dataset:
the analysis and applications of dynamic impression insole

Conditions: Metatarsalgia

Summary: the aim of the study was to investigate the effectiveness of dynamic impression insoles on plantar pressure and pain reduction. a dynamic impression insole was made by sequential padding with plastazote and p-cell under daily walking compression. the pain levels and plantar pressure with the use of dynamic impression insole were assessed and compared with 7-mm ethylene vinyl acetate (eva) control, 9-mm uncompressed plastazote and custom molded insoles. plantar pressure was measured by a pedar-x mobile system, and pain level was assessed using a visual analog scales.

toe deformities may cause prominence of the metatarsal heads (mth) and distal displacement of fat-pad cushion beneath the mth, resulting in the metatarsal pain. foot pain frequently leads to limitation of activities of daily life and deterioration of life quality. foot orthoses have been commonly used in clinical practice to reduce plantar pressure and subsequent pain. however, the therapeutic efficacies of custom molded insoles with a metatarsal support vary widely with their designs and materials. we designed a simple and effective method that a dynamic impression insole was made by sequential padding of foams with different compressibility under successive dynamic impression in daily walking. a piece of metatarsal pad and arch support made of eva was attached to the bottom of impressed insole just proximal to the first, second, and third mth according to the foot impression. fifty participants with metatarsal pain were recruited from the podiatry outpatient clinic of taipei veteran general hospital. the plantar pressure measurements were carried out under a comfortable and stable walking speed preferred by the participants one month after the dynamic impression and custom molded insoles were well fabricated. all pressure data were processed with the novel-win multimask analysis software. the purposes of this study were to investigate the biomechanics of dynamic impression insole in plantar pressure and pain reduction.

Eligibility criteria:
inclusion criteria: * adults with metatarsal pain * active in walking without any walking aids exclusion criteria: * people with flexible flat foot * any acute inflammation

Keywords: plantar pressure metatarsalgia insole
postoperative dietary counseling after bariatric surgery

Conditions: Obesity

Summary: this study aims to assess the changes in physical characteristics, food intake, eating behavior, vomiting, and dumping in 100 patients who undergo bariatric surgery. patients are put into one of two conditions; they will either receive standard postoperative care or biweekly counseling sessions with a dietician that will help them with the postoperative diet. patients who receive dietary counseling are anticipated to experience greater weight loss and report less consumption of sugar and fat as compared to patients who do not receive dietary counseling. moreover, patients who receive dietary counseling are predicted to report less frequent nausea, vomiting, and gastric dumping, as compared to patients who do not receive postoperative dietary counseling. this is predicted to result as a consequence of increased dietary adherence evidenced by the former group.

this study aims to assess the changes in physical characteristics, food intake, eating behavior, vomiting, and dumping in 100 patients who undergo bariatric surgery. patients are put into one of two conditions; they will either receive standard postoperative care or biweekly counseling sessions with a dietician that will help them with the postoperative diet. patients who receive dietary counseling are anticipated to experience greater weight loss and report less consumption of sugar and fat as compared to patients who do not receive dietary counseling. moreover, patients who receive dietary counseling are predicted to report less frequent nausea, vomiting, and gastric dumping, as compared to patients who do not receive postoperative dietary counseling. this is predicted to result as a consequence of increased dietary adherence evidenced by the former group.

Eligibility criteria:
inclusion criteria: * body mass index (bmi): 40 to 60 kg(squared) or greater than or equal to 35kg(squared) in the presence of co-morbid medical condition. * subjects must live within 30 minutes of the university of pennsylvania and drive or have ready access to public transportation. * subjects must be able to ambulate without assistance. * subjects will be free of contraindications to bariatric surgery and will have been approved for surgery by both the medical staff and their insurance carrier. * subjects must be able to communicate with the investigator, be legally competent, and provide written informed consent. exclusion criteria: * evidence of significant psychiatric distress that impairs daily functioning, as suggested by a beck depression inventory-ii (bdi-ii) greater than or equal to 25. (individuals with bdi-ii scores greater than or equal to 25 will be referred for appropriate help, as per the requirements of the law in the state of pennsylvania.) * any current substance abuse or dependence disorder. * concurrent psychiatric treatment for any dsm-iv condition * persons who binge eat and report purging behavior (i.e., vomiting, laxative or diuretic abuse, etc.) will be excluded from the study and referred to an eating disorders specialist.

Keywords: standard care nutritional counseling
online patient navigation program for patients with breast cancer

Conditions: Breast Cancer; Supportive Care in Cancer; Patient Navigation

Summary: the goal of this prospective 1:1 randomized controlled trial is to evaluate if an online patient navigation program, designed to identify targeted supportive care needs and to facilitate referrals and web-based interventions to address these needs, can increase patients' access to supportive care services, compared to traditional in-person patient navigation providing referrals to in-person supportive care services the main questions it aims to answer are: * does online patient navigation increase access to supportive care services by ≥30% among patients with breast cancer? * which are the barriers that hinder patients\&#39; access to the supportive care services they require? * what is patients\&#39; level of satisfaction with online patient navigation? researchers will compare the online patient navigation program to traditional in-person patient navigation providing referrals to in-person supportive care services to assess if online patient navigation increases patients' access to supportive care services. participants will: * participate in an online or in-person patient navigation program for 4 weeks * answer the study surveys at baseline and 4 weeks of follow-up


Eligibility criteria:
inclusion criteria: * female sex * age ≥18 years * diagnosis of non-metastatic breast cancer * internet access at home or in their mobile phone * availability to answer the study surveys * provision of signed informed consent exclusion criteria: * disease recurrence * inability to read or write

Keywords: breast cancer supportive care patient navigation online patient navigation
text-med + fans full trial

Conditions: Diabetes

Summary: this is an intervention to study incorporating social support into mhealth interventions for low-income, ed patients with diabetes

diabetes has disproportionately affected the latino population. text-med (trial to examine text message for emergency department patients with diabetes) is a locally designed, successful mobile health (mhealth) intervention for low income latinos with diabetes. social support interventions have likewise been successful at improving patient self-efficacy and disease management but are limited in scale due to two key obstacles: 1) requirements of in-person training of family and friends to be supporters and 2) the need to coordinate schedules and physical location between the patient and their supporter. mhealth can overcome these obstacles by allowing supporters to be trained remotely via a mobile platform and by allowing communication between a patient and supporter to occur at any time or place. the proposed intervention leverages the success of text-med by augmenting the program with a social supporter that each patient can select from his or her own social support system (family and friend network supporters (fans)), creating text-med+fans. this is a 12 month, randomized study of this intervention. at the completion of the trial, we will evaluate the user experience with text-med+fans, and the impact of text-med+fans on patient motivation, self-efficacy and behaviors through a qualitative analysis of semi-structured individual interviews.

Eligibility criteria:
inclusion criteria: * age \>18 * hba1c\>8.5 * social support person identified and contacted exclusion criteria: * unable to consent * does not speak/read english or spanish

Keywords: mobile health social support health disparity latino
avatar-led digital therapeutic for aiding smoking cessation in sexual and gender minority young adults

Conditions: Cigarette Smoking-Related Carcinoma

Summary: this trial assesses the acceptability and preliminary efficacy of empowered, queer, quitting, and living (eqqual) smoking-cessation intervention for sexual and gender minority young adult smokers. the prevalence of tobacco use among sexual and gender minority (sgm) young adults is more than twice as high as non-sgm young adults, suggesting that existing sgm-related disparities in tobacco use will persist well into the foreseeable future unless sustained efforts are undertaken to address them. eqqual is an online smoking cessation intervention designed specifically for sgm young adult smokers, and may help them quit smoking.

outline: participants are randomized to 1 of 2 arms. arm i: participants receive self-guided, online quit smoking program, called eqqual program a. arm ii: participants receive self-guided online quit smoking program, eqqual program b.

Eligibility criteria:
inclusion criteria: * demographic criteria: * participants must self-identify being between 18 and 30 years of age * participants must self-identify as a sexual and/or gender minority (i.e., a sexual orientation other than straight and/or gender that doesn't match sex assigned at birth) * participants must currently reside in the united states, with a united states (us) mailing address, and anticipate remaining in the us for the duration of the study (3 months) * smoking criteria: * participants must self-report smoking at least 1 cigarette per day in the 30 days prior to screening * treatment accessibility: * participants must self-report having at least weekly internet access for the next three months * participants must self-report being willing and able to stream audio and video online for this study * participants must self-report current use of a personal email account * participants must self-report current use of text messaging * other criteria: * participants must self-report that they are interested in participating in the study for themselves (versus \[vs\] someone else) * participants must self-report that they have not participated in one of our prior smoking cessation studies * participants must self-report that they are comfortable reading, writing, and speaking english * participants must self-report that they understand and agree to the conditions of compensation * participants must self-report that they are not currently incarcerated * participants must be willing to use the assigned intervention program, complete the study assessments, and consent to participate in this study * participants must be willing to upload a photo of themselves (face visible) exclusion criteria: * participants must not be currently using other tobacco cessation treatments at the time of screening, including pharmacotherapy or behavioral support (but initiating these treatments during the study is allowed) * participants must not be a member of the same household as another research participant * having a google voice number as their sole phone number
cirrhosisrx cds system

Conditions: Cirrhosis; Decision Support Systems, Clinical

Summary: the aim of the study is to compare the effect of cirrhosisrx, a novel clinical decision support (cds) system for inpatient cirrhosis care, versus "usual care" on adherence to national quality measures and clinical outcomes for hospitalized patients with cirrhosis.

each year, there over 200,000 hospitalizations for cirrhosis in the united states. over one-third of these patients are readmitted within 30 days, and up to 10% will die in the hospital. despite national quality measures and care guidelines, cirrhosis care remains suboptimal and highly variable. clinical decision support (cds) systems present an attractive strategy to improve guideline-adherence due to low implementation costs. these systems, however, remain largely untested in cirrhosis care and it remains unknown whether they are effective at improving guideline-adherence and whether improving guideline-adherence changes clinical outcomes in cirrhosis care. the investigators have designed "cirrhosisrx," a cirrhosis-specific cds system, to address these evidence gaps. this study intends to compare effect of cirrhosisrx versus "usual care" on adherence to quality measures and clinical outcomes through a pragmatic randomized controlled trial (prct). randomization will be based on stepped-wedge cluster randomization of treatment teams at our institution.

Eligibility criteria:
inclusion criteria: * all adult (age ≥ 18 years) patients who have a previous history of cirrhosis identified based on 1+ chronic liver disease and 1+ cirrhosis (or its complications) international classification of diseases, revision 10 diagnosis codes admitted at our institution. exclusion criteria: * children (age \< 18 years) * patients who do not meet the cirrhosis definition criteria as noted above * ambulatory patients
dexamethasone as adjuvant to ropivacaine in wound infiltration for postoperative analgesia following spinal surgery

Conditions: Lumbar Spinal Stenosis; Lumbar Disc Herniation; Lumbar Spondylolisthesis; Lumbar Spine Instability

Summary: introduction: improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists. pain following spinal surgery, can lead to significant morbidity, limit early mobility, and increase the risk of chronic pain. this trial examines the analgesic effects of dexamethasone as an adjuvant to ropivacaine in wound infiltration after lumbar surgery. methods: in this study, we randomly assigned sixty patients undergoing lumbar laminectomy and/or osteosynthesis into two groups of 30 patients each. the control group (r-group) received only ropivacaine (150 mg of ropivacaine 7.5% (20 ml) added to 2 ml of normal saline in the wound infiltration), while the intervention group (rd-group) received ropivacaine with the addition of dexamethasone (150 mg of ropivacaine 7.5% (20 ml) added to 8 mg of dexamethasone in the wound infiltration). both groups were administered patient-controlled analgesia (pca) with morphine for self-medication. postoperatively, a blinded evaluator assessed pain at h0, recorded the assessment of surgical scar pain using the visual analog scale (vas) at 4, 6, 12, 24, and 48 hours, as well as the time to the first opioid request, cumulative morphine consumption, opioid-related side effects, and length of stay. all patients were scheduled for a 3-month follow-up call to monitor chronic pain progression.


Eligibility criteria:
inclusion criteria: * asa i or ii and diagnosed with lumbar disc herniation, lumbar spinal stenosis, or lumbar degenerative spondylolisthesis requiring surgical treatment such as lumbar laminectomy and/or lumbar osteosynthesis. exclusion criteria: * patients with altered communication capacity, previous spinal surgery, neuropathic pain, allergy to opioids, dexamethasone, or local anesthetics, active infection or tumor history, traumatic injury, chronic use of steroids or opioids, severe kidney, hepatic, or pulmonary failure, delayed extubation in post-anesthesia care unit (pacu), major bleeding during or after surgery, or surgical revision within the first 24 hours were excluded from the study.
implant retained cad-cam ceramic crowns

Conditions: Prosthesis Survival

Summary: newly available ceramic cad-cam blocs containing a screw channel for chairside-made crowns to be adhesively cemented to a tibase abutment and screw-retained to an implant are appealing to the clinician, considering the time efficiency (one appointment) and overall lower costs as no dental laboratory is involved. the hypotheses are that the biological (bop, pd, pcr, implant bone level) and mechanical outcomes (fracture, loss of retention, wear) are equivalent to implant screw-retained porcelain-fused-to-metal (pfm) crowns over a 5 year observation time.this rct will provide key information as to the cost/benefit, suitability and/or limitations of these chair-side hybrid-abutment crowns in the posterior region.

this rct involves the university of geneva dental school and four private practices for which the geneva hospital ethic committee's approval is required. patients in need for replacement of single unit posterior teeth will be recruited at the dental school as well as in the 5 private practices based on specific selection criteria. patients will be randomly assigned to a restorative group using a computer-generated random number table for allocation. the cad-cam blocs containing a screw channel for implant-retained chairside-made single-unit hybrid-abutment crowns are 1) lithium-disilicate glass-ceramic (e.max cad) (g1) and 2) feldspath-ceramic infiltrated by polymer (enamic) (g2). the cad-cam crowns are adhesively cemented to titanium base abutments (ti-base) and screw-retained to titanium implants (straumann standard plus) in the premolar (rn) and molar region (wn). controls are screw-retained pfm crowns (g3). the number of crowns in each group is n=30 (15 molars and 15 premolars) which gives a total of 90 crowns for this study. participants are recalled after 1 week-10 days after crown insertion (baseline, t0) and then yearly during 5 years (t1-t5). digital x-rays are taken at t0, t1, t3 and t5 with repositionable individual resin bite registrations.

Eligibility criteria:
inclusion criteria: * absence of relevant medical condition * need for a single crown on implant in the molar or premolar region with existing adjacent and antagonist teeth * no active periodontal or pulpal diseases * teeth with good restorations * straumann regular (premolar) and wide neck (molar) implants, osseo-integrated for a minimum of 2 months and facial keratinized mucosa width of at least 2 mm * patient agrees to return for follow-up examinations during 5 years * patient agrees to immediately inform the operator in case of problem exclusion criteria: * evidence of bruxism * 2 adjacent implants * implants placed of-axis
effects of adding photobiomodulation to a specific therapeutic exercise program for the treatment of individuals with chronic nonspecific neck pain.

Conditions: Neck Pain; Chronic Pain

Summary: in the current clinical and scientific reality, conservative treatment is the most coherent clinical management with a view to the proper rehabilitation of patients with chronic neck pain, with a trend towards the use of therapeutic exercise. however, some uncertainty about the effectiveness of therapeutic exercises still remains, requiring further studies with high methodological rigor, especially with regard to multimodal treatment, such as the combination of therapeutic exercises with photobiomodulation. thus, the objective of this project is to evaluate the effects of adding photobiomodulation to a program of specific therapeutic exercises for the treatment of individuals with chronic non-specific neck pain. for this, 60 participants will be randomized into two groups: therapeutic exercise group + photobiomodulation (n = 30), and therapeutic exercise group (n = 30). there will be 10 treatment sessions and participants will be evaluated before, after the 10 sessions, and 4 weeks after the end of treatment using the numerical pain scale, neck disability index, catastrophic thoughts about pain scale, and tampa kinesiophobia scale. in the statistical analysis, a linear mixed model will be applied, considering the interaction between the time and group factors. finally, the addition of photobiomodulation to a therapeutic exercise program is expected to generate clinical improvements for patients with chronic neck pain.


Eligibility criteria:
inclusion criteria: * with chronic neck pain (for more than 90 days) * identified according to the following criteria: ndi score ≥ 5 * numerical pain scale (end) score ≥ 3 at rest or during active neck movement exclusion criteria: * individuals who had a history of cervical trauma; head, face, or cervical surgery * degenerative diseases of the spine * pain radiating to the upper limbs * having been submitted to physiotherapeutic treatment for the cervical region in the last three months * use of analgesics, anti-inflammatory drugs, or muscle relaxants in the last week; the presence of systemic diseases * medical diagnosis of fibromyalgia.
3d craniofacial cephalometric analysis

Conditions: Malocclusion

Summary: development of three-dimensional craniofacial cephalometric analysis for virtual planning in orthognathic surgery.

cone beam computed tomography is taken for diagnosis independently from this study. investigators are using this medical imaging for performing the 3d cephalometric analysis. investigators apply a set of well described landmarks of three-dimensional reconstruction of the skull from patients suffering from diverse craniofacial malformations. then a set of specific measurements is taken from the patient and provide insights how to modify the anatomy of the patient to improve the skull's architecture and symmetry

Eligibility criteria:
inclusion criteria: * maxillomandibular dysmorphoses, * facial asymmetry, * craniofacial syndromes exclusion criteria: * patients with orthodontic treatment only * growing patients

Keywords: cephalometry three-dimensional ct scan lateral radiography facial symmetry maxillomandibular dysmorphoses