a study to assess safety and improvement in skin barrier after using 2 facial sunscreens in adults with sensitive skin

Conditions: Healthy

Summary: the purpose of this trial is to evaluate 1) the dermatological tolerability of 2 facial sunscreens after 21 (+2) days of use under normal conditions on the half face by adult subjects with sensitive skin, 2) compare the efficacy of investigational products (ips) after 21 (+2) days of use in adult subjects with sensitive skin, under dermatological supervision through the following evaluations: the transepidermal water loss in the nasolabial region; the sensory perception of the subjects using the sensory perception questionnaire, after 21 (+2) days of use under normal conditions; the sensitivity of the subjects' skin after the first application of each product using a questionnaire on the perception of signs of discomfort.


Eligibility criteria:
inclusion criteria: * participants vaccinated against coronavirus disease 2019 (covid-19) * participants of any gender * participants of any ethnicities according to brazilian institute of geography and statistics (ibge) criteria * phototype ii to iv according to fitzpatrick's classification * participants - in good health based on medical history reported by the subject * participants presenting intact skin on the face, with the exception of clinical signs characteristic of sensitive skin * participants who declare themselves as having sensitive skin (according to the institute's sensitive skin questionnaire, completed in the recruitment phase and reconfirmed by the physician on the day of inclusion) * able to read, write, speak and understand portuguese (able to read and understand the documents delivered and what is explained to them) * participants who agree to maintain their cosmetic habits during the study period * participants who agree to maintain their cosmetic habits during the study period * participant who signed the informed consent document (icd) * agreement to adhere to the procedures and requirements of the study and to attend the site on the day(s) and time(s) determined for the assessments * participant that intend to complete the study and is willing and able to follow all study instructions exclusion criteria: * participants that have had allergies or adverse reactions to common topical skincare products, including sunscreens, medications, or other products that the investigator considers relevant * participants that present a skin condition that may influence the study results (specifically psoriasis, eczema, atopic dermatitis, cutaneous xerosis, intense erythema, or active skin cancer). mild erythema and xerosis associated with a sensitive skin condition are acceptable for eligibility * participants that present primary/secondary lesions (for example: scars, ulcers, vesicles, vitiligo) or tattoos on the test areas * participants that have undertaken cosmetic or dermatological treatment, invasive or non-invasive, in the test areas within 3 weeks before the beginning of the study and during the study * participants that have self-reported type 1 or type 2 diabetes or are taking insulin or another anti-diabetic medication * participants that are taking a medication that would mask an adverse event (ae) or influence the study results, including: immunosuppressive or steroidal drugs within 2 months before visit 1; non-steroidal anti-inflammatory drugs within 5 days before visit 1; antihistamines within 2 weeks before visit 1. if an individual is taking one of these medication types, the individual is not considered eligible at screening. however, if a subject begins using one of these medications during the study, the study physician should be consulted to consider the impact of the specific medication on subject safety and/or the study results, as described in section "concurrent/concomitant medication" * participants that are self-reported to be pregnant or planning to become pregnant during the study * participants that have a history of a health condition/situation which may put the individual at significant risk, influence the study results, or interfere significantly with the individual's participation in the study * participants that are simultaneously participating in any other study * participants that are employees/contractors or immediate family members of the principal investigator (pi), study site, or sponsor * history of non-adherence or unwillingness to adhere to the study protocol * any condition not previously mentioned that, in the opinion of the pi, may compromise the study evaluation