effect of consuming food cooked in iron utensils on iron status in children with iron deficiency anemia (ida)

Conditions: Iron Deficiency Anemia

Summary: iron deficiency is a common problem in the world and more so in the developing countries with a prevalence of 64 % (using who cut-off values of hb \<11.0 g/dl) among children, 9-36 months of age. the pediatric population is especially vulnerable to iron deficiency anemia due to low intake of iron rich foods, rapid growth with high demand and losses of iron from body especially with the commonly found worm infestations in children. mild to moderate iron deficiency is widely prevalent in children and can have several implications including failure to thrive, poor scholastic performance, repeated infections etc. dietary measures along with therapeutic measures are recommended to combat iron deficiency anemia (ida). however, iron rich foods alone cannot be relied upon as a sole step to counter ida. the utensil in which the food is cooked plays a major role in determining the final iron content of food. several studies have documented that most of the foods (90%) contained significantly more iron when cooked in iron utensils depending on the acidity, moisture content, and cooking time of food.the daily dietary intake could vary from 11 to 6 mg of iron if iron utensil was used for cooking \[3\]. food cooked in aluminum (al) utensils has a higher al content which can be detrimental to healthy individuals and particularly to patients with chronic renal failure.in healthy persons, diseases of central nervous system, as well as of hematopoeitic system, skeletal system and respiratory system are described due to excess of aluminium consumption. aluminium utensils have fast replaced iron cooking pots from indian kitchens, hence a study to know the effectiveness of iron cooking pot as a measure to combat ida is necessary. studies have shown the utility of cooking food in iron utensil in prevention of ida but the investigators did not come across a study to document the use of this modality in treatment of ida in children. since the investigators anticipate that the improvement of iron status will be a gradual process, so the investigators decided to evaluate the utility of cooking food in iron utensils on iron status in children with non-severe ida (hb% \ 5 gm %. to test the following hypothesis "use of iron utensils for cooking food will result in improvement in iron status in pediatric patients with nonsevere iron deficiency anemia."

dietary advice and iron therapy are considered the cornerstones of treating a patient with non-severe ida. the foods that are rich in iron include meat and poultry products, egg, green leafy vegetables, jaggery, dry fruits etc. iron in food is of two types viz. haem iron and non haem iron. haem iron has excellent bioavailability but the bioavailability of the non-haem iron in the food stuffs is considerably affected by the presence of substances like phosphates, phytates, tannins and fibres. on the other hand, ascorbic acid, sugars and other acidic substances in the food enhance the iron absorption. the bulk of food consumed by a child is too less to provide him with therapeutic amounts of iron form diet alone. in the developing countries, the child is quite unlikely to get poultry products and meat as a source of haem iron. if in this situation, the child is provided with food cooked in iron utensil, then it provides additional iron to meet the increased demand. this will not only be cost effective but it will also alter the cooking practices and thereby have a long term effect on the iron status of the entire family. thus it will treat the ida in the index case and will also benefit other family members who may be having borderline or overt iron deficiency. this cost effective measure if incorporated in the health policy of the country will certainly have widespread positive implications on the health of the general population.

Eligibility criteria:
inclusion criteria:inclusion criteria 1. age: 2-12 years, 2. resident of urban nagpur 3. diagnosed as having non-severe ida defined as hb% \> 5gm% but less than cut off point for age for diagnosing anemia. exclusion criteria: 1. suffering from hemoglobinopathy or iron overload due to any cause 2. receiving iron therapy 3. malabsorption 4. bleeding diathesis 5. chronic illness 6. participation in another trial in last 30 days

Keywords: iron deficiency anemia dietary intervention to evaluate a cheap and sustainable dietary intervention to improve the iron status of the entire family of the index case of non-severe iron deficiency anemia.