Kornimate/medical-research-clean huggingface dataset:
effects of sleep restrictions on maximal strength, muscle power, and strength endurance in resistance-trained women.

Conditions: Sleep Restriction; Sleep

Summary: the study aims to see how acute sleep restriction will affect women resistance trainers. above all, the investigators will be interested in observing the relationship between shorter sleep and athletic performance, as well as other important aspects, such as their level of motivation to exercise, how much pain participants felt during exercise and how demanding they found exercise. the investigators assume that differences in subjective measures (such as pain levels, motivation and mood) will be most apparent.

participants would take part in two identical experimental sessions under two sleep conditions: with sleep restrictions (sr), where will experience acute sleep restriction the night before the test session (i.e., 3 h of early sleep restriction versus normal sleep); with the control condition (con), where participants will follow their habitual sleep-wake routines. every session would separated by a 1-week interval. the average sleep duration (con) is going to be estimated by using actigraphy motionwatch 8 for 5 days (from monday to friday). female athletes will receive accelerometers one day before experimental sessions. participants will be asked to wear them on their non-dominant wrists from 8 p.m. to the next morning (experimental sessions day). the participants would complete the morning session with a battery of physical tests, measuring several components of specific physical performance capacity and cognitive function. during the experimental sessions, participants would be at the luteal or follicular phases excluding the period of bleeding (4-5 days) and the time immediately before planned bleeding (3 days before), because this can have a bad influence on sleep.

Eligibility criteria:
inclusion criteria: * a minimum of 3 years of training experience; * practicing physical activity for the last 6 months at least 3 times per week for 2h * current medical qualification for competitive sport exclusion criteria: * diseases that can have a bad influence on the menstrual cycle (e.g. polycystic ovarian syndrome, endometriosis); * using hormonal contraception; * regularity of the menstrual cycle. * diagnosed cardiovascular, metabolic, gastrointestinal, or neurological diseases; * movement, neuromuscular or musculoskeletal disorders; * taking medications and supplements that may affect fitness test results; * taking supplements that may affect biochemical test results * sleep disorders * psqi \>5

Keywords: acute sleep restriction early sleep restriction
screening in trauma for opioid misuse prevention

Conditions: Opioid Use Disorder

Summary: the current study seeks to begin the crucial work of creating effective protocols to prevent opioid misuse, addiction, and related complications by developing and pilot testing an opioid risk screening protocol at wisconsin trauma centers.


Eligibility criteria:
inclusion criteria: * inpatient victim of traumatic injury * expected need for post-discharge outpatient opioid analgesia * english speaking * disposition to short-term rehabilitation facility is allowed exclusion criteria: * disposition to a skilled nursing or long-term acute care facility * current active opioid use disorder or current active participation in a program of recovery for another substance use disorder
tns for major depressive disorder: a phase ii randomized controlled trial

Conditions: Depressive Symptoms

Summary: this is a phase ii, randomized, sham controlled, clinical trial. this clinical trial has as primary objective to evaluate the effect of the trigeminal nerve stimulation (tns) on depressive symptoms measured by the hamilton depressive rating scale version 17 items (hdrs-17) in patients with moderate / severe depressive episode.


Eligibility criteria:
inclusion criteria: 1. patients between 18 and 69 years 2. patients with a diagnosis of depression according to the scid 3. score greater than or equal to 18 on the hamilton rating scale 17-item version (equivalent to moderate or severe depressive episode) 4. agreement to participate in the study as recommended in the ic. exclusion criteria: 1. patients with psychiatric indication for hospitalization 2. patients with psychiatric comorbidity 3. patients with a diagnosis of personality disorder 4. presence of severe neurological or medical diseases such as neoplasms in activity, neurodegenerative diseases and chronic diseases uncompensated.

Keywords: depression cranial nerve stimulation trigeminal stimulation
evaluation of the efficacy of ambu® ascope for intubation in cancer tongue

Conditions: Difficult Intubation

Summary: this study compares the ascope with standard fiberscope using the nasal route of intubation in patient having sever difficult airway (having posterior one third cancer tongue with fixed mobility)

patient will be allocated into two group according to the type of endoscope used group (f) fibro scope group and group (a) the ambu ascope group the timer will be started (t0), when touching the fiberscope or a scope. the standard fiberscope or a scope2 will be introduced through the nostril and advanced through the vocal cords, once carina identified the time will be recorded ( t1) when correct positioning of the trachea confirmed by detection of the end-tidal co2 curve on capnography (t2).

Eligibility criteria:
inclusion criteria: 1. adult patients of asa physical status i and ii who will be scheduled for posterior third fixed cancer tongue with severe difficult airway requiring naso-tracheal intubation 2. aged 18-70 years exclusion criteria: 1. asa 2 or 4 2. pregnant
evaluation of a pilot shard-care program for patients with chronic pain in the champlain-lhin

Conditions: Chronic Pain; Quality of Life

Summary: the study is evaluating an intervention consisting of a five week online mindfulness program for patients being referred to the pain clinic and triaged to econsult. a pain specialist will be in contact with the patient's family physician to confirm it's appropriate and then a therapist will initiate contact with the patient to assess eligibility. the therapist will be a registered health professional with experience with patients with chronic health problems and will be supporting the online program where the participant will have communication access to them. questionnaires will be sent at three time points to assess changes.

there are currently many patients waiting to be seen at the ottawa hospital pain clinic (tohpc). however, many patients with chronic pain (cp) have exhausted medical options or could be served in the community with appropriate support for them and their family physicians (fps). econsult is a secure web-based platform that allows tohpc physicians to provide pain management advice within seven days within the champlain local health integration network (lhin). in order to provide enhanced care to patients and improve the uptake of econsult for cp, the investigators have developed a shared care model for cp in the champlain lhin. this program combines the use of econsult for fps and a 5-week self-directed online cp management program with therapist support available as needed.

Eligibility criteria:
inclusion criteria: * aged 18-years or older * ability to understand oral and written english * report chronic pain (≥3months) exclusion criteria: * refusal or inability to provide informed consent * severe, unstable or untreated psychiatric conditions (ex. severe depression, psychosis, bipolar, etc.) * does not have access to the internet or electronic device capable of watching videos

Keywords: mindfulness chronic pain disability quality of life online
hip-stitch (wound recovery after tha)

Conditions: Wound Healing Disturbance of

Summary: this prospective randomised trial will investigate the effect of four different suturing techniques (monocryl, vicryl rapide with indermil skin glue, dermabond prineo, and stryker zip) on the amount of aberrant wound recovery within 14 days after total hip arthroplasty at the rhoc in zoetermeer, the netherlands. this will be done by assessing photographs of the plaster and photographs of the operation wound with a self-developed classification model. the photographs of the plaster will be taken by the test subject at home at 3 days and 11 days postoperatively. the photographs of the operation wound will be taken by a member of the research team, and the doctor's assistant, respectively, during a visit to the outpatient clinic at 7 days and 14 days postoperatively. hypothesis: monocryl sutures give the highest amount of aberrant wound recovery within fourteen days after primary tha.


Eligibility criteria:
inclusion criteria: * eighteen years or older. * scheduled to undergo total hip arthroplasty via the anterior approach for any indication at the rhoc. * no prior operations to the hip which is to be operated on. * a good command of the dutch language * able to give written informed consent. exclusion criteria: * usage of cytostatics in the period ranging from fourteen days prior, to ninety days after the operation. * unable to, or difficulty with communicating in the dutch language (e.g. due to mental disability, inability to understand/speak/write dutch, et cetera).

Keywords: aberrant wound recovery total hip arthroplasty anterior approach monocryl smooth suture vicryl rapide braided suture indermil topical skin adhesive dermabond prineo skin closure system stryker zip skin closure system
to determine the accuracy of screening for occult renal disease (scored) questionnaire for ckd risk among asian patients

Conditions: Chronic Kidney Disease

Summary: to determine the accuracy of screening for occult renal disease (scored) questionnaire for ckd risk among asian patients


Eligibility criteria:
inclusion criteria: - exclusion criteria: -
diagnosis of urethral stricture with sono-urethrography vs conventional urethrography (sono-urethra)

Conditions: Urethral Stricture Disease

Summary: conventional urethrography is the standard diagnostic evaluation for patients with a suspicion of urethral stricture. the radiation dose of this examination is 5-9 msv. sono-urethrography was introduced in 1988 (mcaninch et al. , j urol 1988); the diagnostic accuracy of sono-urethrography is equal compared to conventional urethrography, with even a better measurement of stricture length and degree of spongiofibrosis with sono-urethrography. however, sono-urethrography remained underused among urologists and radiologists. patients will be randomly assigned into two groups: group a: conventional urethrography group b: sono-urethrography in case sono-urethrography is inconclusive or of poor quality, a conventional urethrography will be performed. the radiation dose in the two groups will be measured. the stricture length and location will be recorded and compared with the perioperative findings in order to evaluate the diagnostic accuracy. the complications of the procedure(s) will be recorded with a questionnaire directly after and two weeks after the conventional or sono-urethrography.


Eligibility criteria:
inclusion criteria: * patients with a suspicion of urethral stricture disease for which an indication of imaging of the urethra exists. exclusion criteria: * transsexual patients. * patients with perineostomy.

Keywords: urethrography
circadian amplification in diabetic retinopathy

Conditions: Diabetic Retinopathy

Summary: this study will test the effects of a 6-week comprehensive circadian optimization intervention amplify-rhythm in patients with diabetic retinopathy. the outcomes of interest are objective and subjective sleep parameters, evening salivary cortisol and melatonin levels, and glucose parameters from continuous glucose monitoring

this study will test the effects of a 6-week comprehensive circadian optimization intervention amplify-rhythm in patients with diabetic retinopathy. the two main components of the intervention are timed light exposure and weekly remote coaching session by psychologist to optimize circadian and sleep behaviors. the outcomes of interest are objective and subjective sleep parameters, evening salivary cortisol and melatonin levels, and glucose parameters from continuous glucose monitoring

Eligibility criteria:
inclusion criteria: * type 2 diabetes * a history of at least moderate non-proliferative diabetic retinopathy * would like to improve sleep * own a smartphone compatible with fitbit. exclusion criteria: * use of melatonin * use of antipsychotics * use of more than one antidepressant. the dose of which needs to be stable for 6 weeks. * illicit drug use * night shift work or travel beyond 2 time zones in the month before enrollment * end stage renal disease requiring renal replacement therapy * history of stroke or transient ischemic attacks * history of dementia or memory impairment * uncontrolled congestive heart failure or recent hospitalization for cardiac condition (6 months) * chronic obstructive pulmonary disease requiring oxygen * severe chronic liver disease such as cirrhosis * ongoing treatment for major medical problems such as cancer * history of severe hypoglycemia defined as hypoglycemic episodes requiring assistance from others within the past six months. * regular use of sedatives and hypnotics (\>2 times/ month). * clinically significant epiretinal membranes, clinically significant lens opacities, or cystoid macular edema, iris neovascularization, iris atrophy, or an asymmetrically shaped pupil, nuclear sclerotic, posterior subcapsular, or cortical lens opacities greater than 2+, a history of pan-retinal photocoagulation. * significant depressive symptoms as assessed by phq-8 questionnaire (score \>14) * no health insurance coverage * history of untreated severe osa. * uncontrolled hypertension (blood pressure ≥ 160/100 mmhg), * uncontrolled diabetes (a1c ≥ 11%)
influence of resistant starch intake in potatoes on blood glucose and satiety responses in overweight females

Conditions: Overweight and Obesity

Summary: resistant starch (rs) is a type of fiber that has unique digestive properties that can impact overall health including glucose homeostasis and satiety. rs found in potatoes can be increased by using certain cooking methods and serving temperatures. the purpose of this trial will compare the acute glycemic and satiety responses after consuming potatoes differing in rs content that are 1) baked then chilled or 2) boiled and consumed hot in overweight females on two separate occasions.

potatoes are a low-cost, nutrient-dense dietary staple in the u.s. rich in complex carbohydrates, potassium, magnesium, and fiber, but low in fat and sodium. starch is the main complex carbohydrate found in potatoes that yields glucose to contribute to overall energy needs. another type of starch found in potatoes is resistant to amylase hydrolysis in the small intestine which is resistant starch (rs). trials using rs as a functional ingredient (\~15-30 g/day) in healthy and overweight adults resulted in improvements in postprandial glucose, insulin sensitivity, satiety hormone response, and subjective satiety. limited data exists using rs naturally found in commonly consumed foods, such as potatoes. altering the cooking methods and serving temperatures of potatoes can influence the amount of rs to impact glucose, satiety hormone response, and subjective satiety. using a cross-sectional, cross-over design, the aim of this study will determine how potatoes 1) baked and chilled or 2) boiled and consumed hot influence postprandial glycemic parameters, satiety hormones (glucagon-like peptide-1, peptide yy, and glucose-dependent insulinotropic polypeptide), subjective satiety, and subsequent energy intake in overweight females.

Eligibility criteria:
inclusion criteria: * overweight and obese (bmi between 28 and 40 kg/m\^2) * any race or ethnicity exclusion criteria: * diabetes or other metabolic disorder, cancer, or cardiovascular disease * smoking * pregnant or lactating * more than 5% weight loss or gain over prior 6 months * following a special diet * sensitivity or aversion to potatoes
liberal versus goal-directed intraoperative fluid therapy in pediatric patients

Conditions: Adverse Anesthesia Outcome

Summary: the objectives of this study are 1) to investigate the influence of different fluid regimen (liberal regimen versus goal directed therapy regimen) on postoperative outcome such as weight gain, delayed gut function recovery, pneumonia and 2) to ascertain the reliability of uscom monitoring using serum lactate and base deficit as control parameters.

liberal regimen = maintenance fluid(4/2/1) + deficit fluid + replacement of third space loss (\>,=10ml/kg/h) goal directed therapy regimen = maintenance fluid + deficit fluid + fluid replaced by hemodynamic monitoring guided.

Eligibility criteria:
inclusion criteria: * body weight \< 15 kg * under going major abdominal surgery such as tumor removal, gut obstruction, pull through, etc. under general anesthesia and invasive arterial pressure monitoring if justified * asa \< or = 3 * duration of surgery \> or = 2 hours exclusion criteria: * cardiopulmonary disease * renal insufficiency * intraoperative complications such as massive bleeding, severe hypotension, prolonged need for mandatory ventilation * reoperation

Keywords: intraoperative fluid pediatric goal directed therapy pediatric with major abdominal surgery asa less than or equal to 3 duration of surgery less than 2 hours body weight more than or equal to 15 kg
hepatitis b challenge dose in adults (v232-059-10)

Conditions: Hepatitis B

Summary: the purpose of this trial is to describe the seroprotection rate (spr) at least 2 years following completion of a primary series with a hepatitis b vaccine (base study v232-059, nct00440531) and 1 month following a challenge dose with a modified process hepatitis b vaccine.


Eligibility criteria:
inclusion criteria: * in general good health based on a medical history. * received 3 doses of an hepatitis b vaccine in base study v232-059, nct00440531 at least 2 years prior to enrollment in this study. exclusion criteria: * known history of previous hepatitis b infection. * history of vaccination with any hepatitis b vaccine within the last 2 years. * history of febrile illness. * known or suspected hypersensitivity to any component of hbvaxpro. * receipt of medication / vaccine that may interfere with study assessments. * known or suspected immune impairment. * pregnant women and nursing mothers.
prophylactic pancreatic stent for the prevention of post operative pancreatic fistula

Conditions: Pancreatic Fistula

Summary: postoperative pancreatic fistula (popf) remains one of the most harmful complications after pancreatic resection. some studies have indicated that endoscopic pancreatic stenting was effective in the treatment of popf. however, the results of prospective rcts for the prophylactic effect of pancreatic stent insertion against popf were controversial. this single center prospective randomized trial was designed to compare the outcome after segmental pancreatectomy with prophylactic drainage stent versus no stent.


Eligibility criteria:
inclusion criteria: * all patients scheduled for elective segmental pancreatectomy exclusion criteria: * subjects for whom ercp procedures are contraindicated * if female, pregnant based on a positive hcg serum or an in vitro diagnostic test result or breast-feeding * age less than 18 year * emergency surgery * previous pancreatic surgery
effect of rotator cuff training on hand grip in adults

Conditions: Hand Grasp

Summary: purpose of the study: * to investigate the effect of rotator cuff training on hand grip strength in adults with different body mass index. * to investigate the effect of rotator cuff training on hand grip static endurance in adults with different body mass index. * to investigate the effect of rotator cuff training on hand grip dynamic endurance in adults with different body mass index. * to investigate the effect of rotator cuff training on upper limb function in adults with different body mass index.

rotator cuff muscles are considered to be the key dynamic muscles in shoulder stabilization since they contribute significantly to shoulder stability in a number of different ways. they work not only as a dynamic stabilizer but also as static stabilizers because of their orientation and location around the shoulder joint. several studies revealed the strong relationship between the rotator cuff muscles and hand grip strength. studies proved the strong correlation between grip strength and rotator cuff strength ,which suggests that assessment of grip strength could be used to monitor the function of the rotator cuff, once baseline readings have been attained during training and rehabilitation . previous publications revealed significant positive associations between handgrip strength, body mass index (bmi) and physical activity in adult men and women. worldwide, 31.1% of adults are reported to be physically inactive. some studies and reports indicate that 20% of the global populace within the age range of 18-64 years comply with the minimum physical activity guidelines for improved health. overweight and obesity are identified as a constant negative influence on physical activity, regardless of age. studies proved that weight, height, and bmi have a significant correlation on hand grip strength. as the weight increase hand muscle strength and endurance time also decrease. subjects in this study will be recruited from the students , employees and faculty members of the faculty of physical therapy, cairo university.

Eligibility criteria:
inclusion criteria: 1. adult subjects of both genders their ages between (18 : 35) years old. 2. body mass index between (18.5 : 34.9 ) kg/ m2. 3. dominant hand is the right hand. exclusion criteria: the subjects will be excluded if they have: 1. traumatic conditions of the upper limb. 2. previous orthopedic disorders or neurological deficit of the upper limb. 3. previous surgery of the upper limbs. 4. any sensory problems. 5. neuromuscular disease like multiple sclerosis. 6. pregnancy. 7. cancer patients. 8. subjects under chemotherapy. 9. immunodeficiency diseases. 10. psychological disorders (depression - anxiety). 11. chronic diseases as (diabetes - hypertension).
post-market clinical follow-up of disposable endoscope linear cutting staplers and components

Conditions: Gastric Disease

Summary: this is a multi-center and retrospective cohort study to evaluate the efficacy and safety of disposable linear cutting staplers and components in soft tissue resection, transection and anastomosis.

the disposable endoscopic linear cutting staplers and components developed and produced by jiangsu channel medical device co., ltd. can be used in open or endoscopic surgery of lung, bronchial tissue, stomach and intestine resection, transection and anastomosis. they have been registered in china for many years and have been widely used, and have been certified by the european union in 2021. the number is cim.2021.106.14629. this study intends to conduct a multi-center retrospective cohort study in china, collect clinical application data of chinese patients, conduct statistical analysis on the clinical application data, confirm whether the expected effectiveness and safety are achieved, and further extrapolate to the eu population.

Eligibility criteria:
inclusion criteria: * gender unlimited, age unlimited ② open or endoscopic surgery ③ resection, transection and anastomosis of lung, bronchial tissue, stomach and intestines. * use the study device during surgery exclusion criteria: * patients with contraindications to the product, such as severe mucosal edema, operation of the hemostatic site that cannot be observed, or off-label use of the liver and spleen; * combined with other similar products (staplers) for surgical site excision, transsection and anastomosis; ③ surgical records are incomplete, and information related to major indicators cannot be extracted; ④ other situations that the researcher considers inappropriate for inclusion in the study.

Keywords: stapler anastomosis