fractional co2 treatment of acne scars in asians

Conditions: Acne Scar, Wrinkle

Summary: the objective of this study is to investigate the efficacy and side effects of a fractional co2 laser for treatment of acne scar in asians.

* the objective of this study is to investigate the efficacy and side effects of a fractional co2 laser for treatment of acne scar in asians. * study hypothesis 1. reduction in acne scars based on blinded evaluation of before photos and the one and three month follow-up photos after four full face ellipse juvia with low density treatments with a fluency of 90-105 mj/mtz is statistically significant (5%). 2. the direct clinical blinded evaluated reduction in acne scars based on before photos and the patient in life, by the one and three month follow-up is statistically significant (5%) 3. reduction in fine lines based on blinded evaluation of before photos and the one and three month follow-up photos after four full face ellipse juvia with low density treatments with a fluency of 90-105 mj/mtz is statistically significant (5%). 4. the direct clinical blinded evaluated reduction in fine lines based on before photos and the patient in life, by the one and three month follow-up is statistically significant (5%). 5. reduction in pigmented disorders based on blinded evaluation of before photos and the one and three month follow-up photos after four full face ellipse juvia with low density treatments with a fluency of 90-105 mj/mtz is statistically significant (5%). 6. the direct clinical blinded evaluated reduction in pigmented disorders based on before photos and the patient in life, by the one and three month follow-up is statistically significant (5%). 7. improvements in skin texture and pore size based on blinded evaluation of before photos and the one and three month follow-up photos after four full face ellipse juvia with low density treatments with a fluency of 90-105 mj/mtz is statistically significant (5%). 8. the direct clinical blinded evaluated reduction in skin texture and pore size based on before photos and the patient in life, by the one and three month follow-up is statistically significant (5%).

Eligibility criteria:
inclusion criteria: * numbers of volunteers: 10 healthy men and women * aged at least 30 year old * skin type: 1 - 4 * degree of suntan: none - light * skin condition: visible acne scars exclusion criteria: * fitzpatrick skin types 5-6. * patients with lesions with any clinical suspicion of being pre-cancerous or skin malignancies of any kind. * patients with skin diseases associated with koebner phenomena. * patients who have used botox or filler injection to the periorbital or perioral regions 12 months prior or during the study. * patients who have used topical retinoids, aha under prescription or vitamin c, 3 months prior to or during the study. * patients who are pregnant or who wish to become pregnant and lactating women. * patients who have been exposed to sun within 2 week from date of treatment. * patients prone to hypertrophic scars or keloids * patients who have previously undergone laser resurfacing may not be suitable for yet another procedure. * patients undergoing oral retinoid therapy for acne in the past 6 months. * patients who suffer from any serious medical condition, including diabetes, bleeding diathesis, delayed wound healing or prednisolone intake. * patients with wound infections (herpes, other) on the day of treatment. * patients with moderate and severe inflammatory acne, immunosuppressed patients, history of vitiligo. * patients with unrealistic concerns/expectations and inability to do the appropriate post-operative care.

Keywords: acne scar, wrinkle, pigmentation, fractional co2 laser