catchu: a quantitative multisensory falls-assessment study

Conditions: Fall Injury; Age Problem; Well Aging; Sensory Disorders

Summary: the ability to successfully integrate information across sensory systems is a vital aspect of functioning in the real world. to date, only a few studies have investigated the clinical translational value of multisensory integration processes. previous work has linked the magnitude of visual-somatosensory integration (measured behaviorally using simple reaction time tasks) to important cognitive (attention) and motor (balance, gait, and falls) outcomes in healthy older adults. while multisensory integration effects have been measured across a wide array of populations using various sensory combinations and different neuroscience approaches, a gold standard for quantifying multisensory integration has been lacking. the investigator recently developed a step-by-step protocol for administering and calculating multisensory integration effects in an effort to facilitate innovative and novel translational research across diverse clinical populations and age-ranges. however, patients with severe medical conditions and/or mobility limitations often experience difficulty traveling to research facilities or joining time-demanding research protocols. using the aforementioned protocol, the study team invented a mobile multisensory falls-assessment iphone app called catchu to facilitate physician discussion and counseling of falls in older adults during clinical visits (e.g., annual wellness visits with a subsequent telehealth call), in an attempt to alleviate disability, promote independence, and increase quality of life for older adults. the investigator team has provided a cross-sectional research proposal for a pilot study of 300 patients (over a 24-month period) in order to demonstrate acceptable-to-excellent predicative accuracy of catchu for identifying older adults at-risk for falls.


Eligibility criteria:
general inclusion criteria: 1. adults aged 65 and older, residing in new york metropolitan area who plan to be in area for next three or more years. 2. able to speak english at a level sufficient to undergo our assessment battery. 3. ambulatory. participants are classified as 'non-ambulatory' if they are unable to leave the confines of their home and attend a clinic visit. these include participants who are bed-bound as a result of severe medical illness or those who require assistive medical devices (respiratory support or ventilators) that cannot be transported or those who cannot complete our mobility protocols. we will not exclude participants who use walking aids (canes, crutches) for ambulation. participants who require walking aids to walk outside but are able to complete our mobility protocols without an assistive device or the assistance of another person will not be excluded. general exclusion criteria (one or more criteria): 1. presence of dementia as defined as a score of ≥ 2 on the alzheimer's disease 8 (ad8) or \< 25 on the montreal cognitive assessment (moca). these cut scores and procedures have been validated in our and other aging studies. 2. serious chronic or acute illness such as cancer (late stage, metastatic, or on active treatment), chronic pulmonary disease on ventilator or continuous oxygen therapy or active liver disease. individuals with recent cardiovascular or cerebrovascular event (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass graft, or stroke) will not be excluded if they meet above inclusion criteria. many of these chronic conditions are very common in older adults. hence, mere presence of these conditions will not be used to exclude participants if well controlled or of mild severity and if participants are able to complete training and mobility tasks. 3. mobility limitations solely due to musculoskeletal limitation or pain (e.g., severe osteoarthritis) that prevent participants from completing mobility tests. 4. any medical condition or chronic medication use (e.g., neuroleptics) in the judgment of the screening clinician that will compromise safety or affect cognitive functioning or terminal illness with life expectancy less than 12 months. 5. progressive, degenerative neurologic disease (e.g., parkinson's disease or als) diagnosed by study clinician or as per medical history. 6. presence of clinical disorders that overtly alter attention like delirium. 7. hospitalized in the past 6 months for severe illness or surgery that specifically affects mobility (e.g., hip or knee replacement) and that prevent participants from completing mobility tests or plans for surgery affecting mobility in the next 6 months. 8. severe auditory, visual, or somatosensory self-reported impairments. visual acuity will be screened using a snellen chart by the psychological assistant. presence of neuropathy will be assessed using the michigan neuropathy screening instrument. 9. active psychoses or psychiatric symptoms (such as agitation) noted during the clinic visit that will prevent completion of study protocols. past history of these symptoms or presence of psychiatric illness not used as exclusion criteria. 10. living in nursing home. 11. participation in another intervention trial. participants can participate in other observational studies.

Keywords: falls aging multisensory integration