Kornimate/medical-research-clean huggingface dataset:
knowledge, attitude and barriers of egyptian and sudanese dentists in providing oral care to geriatric patients

Conditions: Knowledge, Attitude and Barriers of Egyptian and Sudanese Dentists in Providing Oral Health Care to Geriatric Patients

Summary: the goal of this observational study (cross sectional study) is to assess the level of knowledge of egyptian and sudanese dentists about the oral health care needs of geriatric patients and to evaluate the attitude towards treating geriatric patients and barriers in providing care. the data collection by validated questionnaires. the dentists would fill out structured surveys addressing their knowledge, attitudes, and perceived barriers regarding geriatric dental care.


Eligibility criteria:
inclusion criteria: * post graduated sudanese and egyptian dentists currently practicing in egypt and sudan * experience: dentists who have been practicing for at least 1 year to ensure they have enough experience to have formed opinions and practices regarding geriatric care. * age: 20-60 years exclusion criteria: * • dentists not providing geriatric care: dentists who exclusively work with paediatric and do not treat elderly populations will be excluded.

Keywords: knowledge, attitudes, and barriers of egyptian and sudanese dentists - geriatric patient-
sitagliptin vs. pioglitazone as add-on treatments in patients with type 2 diabetes uncontrolled on the full-dose metformin plus sulfonylurea

Conditions: Uncontrolled Type 2 Diabetes Mellitus

Summary: this study has been designed to investigate the comparative effects of sitagliptin vs. pioglitazone as add-on treatments in patients with type 2 diabetes who were uncontrolled on the full-dose of metformin and sulfonylurea


Eligibility criteria:
inclusion criteria: * clinical diagnosis of type 2 diabetes according to the american diabetes association * baseline level of 7% ≤ a1c \< 11% despite a minimum 6 months period of active treatment with metformin 2000 mg/day plus gliclazide 240 mg/day (uncontrolled type 2 diabetes) exclusion criteria: * acute or chronic diseases of heart, lung, kidney, * active or past infectious conditions * malignancy
mold exposure and impact on asthma control in french asthmatic children

Conditions: Asthma in Children

Summary: observational, multicenter, study conducted in 12 hospitals in the nord and pas-de-calais departments. the aim of this study is to describe the relationship between reported exposure to molds and asthma control in a pediatric population. each patient followed by a specialized asthma pediatrician in one of the study center will be proposed to participate in the study. children aged 1 to \< 18 years, with asthma diagnosis, based on the assessment of a specialized physician after a follow-up of at least 6 months inclusion, non-inclusion and exclusion criteria will be verified by the investigators. the questionnaires will be completed during the consultation, collected by the physician in charge of the consultation and sent to the principal investigator for data entry. inclusion will take place over a period of 12 consecutive months from the date of obtaining regulatory approval.


Eligibility criteria:
inclusion criteria: * children aged 1 to \< 18 years, with asthma diagnosis, based on the assessment of a specialized physician after a follow-up of at least 6 months, follow-up in one of the study center in nord and pas de calais departments (lille, lens, tourcoing, valenciennes, arras, roubaix, seclin, armentières, calais, boulogne/mer, dunkerque, ghicl-saint vincent) over an inclusion period of 12 months exclusion criteria: * children living ≤ 50% of the weekly time in their primary home (e.g., shared custody) * children whose living arrangement characteristics are difficult to analyze (e.g., child accompanied by grandparents or by the parent without primary custody) * children whose residence has recently changed, making it impossible to assess the impact of the living arrangement over the past year * children living outside of the nord and pas-de-calais departments * children whose parents are unable to complete the questionnaire

Keywords: asthma children mold moisture asthma control
the clinicaltrail of the effection which of phrenic block using in non-intubated video-assisted thoracoscopic surgery

Conditions: Phrenic Nerve Paralysis

Summary: putting 80 patients divided into group s（non-intubated general anesthesia combine with paravertebral blocks、surface spray anesthesia and vagus block） and group d（non-intubated general anesthesia combine with paravertebral blocks、surface spray anesthesia、vagus block and phrenic block）randomly,compare the volume of anesthetic and the number of increasing anesthetic during operation were compared between the two groups.if the date of group s greater than group d，it shows that the effect of anesthetic effect of group d is better than group s.

1. put 80 patients divided into group s（non-intubated general anesthesia combine with paravertebral blocks、surface spray anesthesia and vagus block） and group d（non-intubated general anesthesia combine with paravertebral blocks、surface spray anesthesia、vagus block and phrenic block）randomly. 2. compare the volume of anesthetic drugs between the two groups. 3. if the date of group s greater than group d，it shows that the effect of anesthetic effect of group d is better than group s.

Eligibility criteria:
inclusion criteria: * the patient agreed to perform non-intubated video-assisted thoracoscopic surgery, and informed the possibility of intraoperative tracheal intubation or thoracotomy. * no conventional anesthesia contraindication, no history of thoracic surgery, good cardiopulmonary function. * there is no severe adhesion and calcification in the thoracic cavity, and no artificial pneumothorax is affected. * the patient has no serious anxiety or depression. * small surgical trauma, simple steps, short time. exclusion criteria: * mallampati≥3. * bmi≥26 kg/m2. * hemodynamic instability. * inr≥1.5. * respiratory infection, persistent cough or airway mucus hypersecretion, high risk of reflux. * nervous system disease,such as seizure or brain edema. * extensive pleural adhesions or once chest surgery. * pao2\ 50 mmhg. * central hypopnea syndrome. * lung isolation should be used to protect the healthy side of the lung. * complicated operation, large trauma, long time, lack of experience or poor cooperation in the surgical team. * contraindications to local anesthetic.

Keywords: non-intubated general anaesthesia video-assisted thoracoscopic surgery phrenic block
operative versus non-operative treatment for atraumatic rotator cuff tears

Conditions: Rotator Cuff Tear

Summary: rotator cuff tears are one of the most common reasons to seek musculoskeletal care in the united states and one of the fastest growing ambulatory surgery procedures. however, data on comparison of operative versus non-operative treatment is lacking and urgently needed.

this is non-blinded, randomized controlled trial. patients will be randomly assigned to either an operative or non-operative course of treatment and will be followed for 12 months from baseline. aim 1: to compare pain and function in patients undergoing operative versus non-operative treatment of atraumatic rotator cuff tears at 12 months of follow-up aim 2: to assess effects of rotator cuff tear size and age on comparative outcomes of operative versus non-operative treatments for atraumatic rotator cuff tears 5u34ar069201-02 nih grant funded the preparatory work for the trial but not the trial itself.

Eligibility criteria:
inclusion criteria: * aged =\>40 years to \<85 years * shoulder pain and/or loss of range of active motion, strength or function * mri-confirmed partial- or full-thickness supraspinatus and/or infraspinatus tear of 4cm or less in longitudinal dimension * medically fit for surgery, defined as category i-iii per american society of anesthesiologists (asa) physical status classification * ability and willingness to provide informed consent exclusion criteria: * primary diagnosis is something other than a rotator cuff tear * history (in last 2 years) of shoulder fracture involving the humeral head on affected side * previous rotator cuff surgery on affected side * isolated subscapularis \&/or teres minor tear on affected side * acute rotator cuff tear caused by a severe trauma * shoulder used as a weight-bearing joint * contraindication to mri (claustrophobia, pacemaker, pregnancy, shoulder implant, etc.) * glenohumeral osteoarthritis on xrays/mri, as determined by recruiting md * grade 4 fatty infiltration of rotator cuff (any tendons) * candidate for shoulder arthroplasty at baseline * non-english speaking

Keywords: arthroscopy physical therapy rehabilitation surgery rotator cuff tear
study of the efficacy of 4 treatments for fecal incontinence in community-dwelling women

Conditions: Fecal Incontinence

Summary: this is a rct aimed to assessing efficacy of kegel exercises,biofeedback, electrostimulation and transcutaneous neuromodulation on women with fecal incontinence, measuring its impact on anorectal physiology, cortical plasticity, clmical severity and the quality of life.

fecal incontinence is a prevalent condition with a major impact on quality of life. currently four treatments are being used in clinical practice: kegel exercises (k), biofeedback (bf), electrostimulation (es) and transcutaneous neuromodulation (nm). results in the literature are discordant and lack methodological rigour making scientific evidence weak. the aim of this study is to assess the efficacy of these four treatments on community-dwelling women and their impact on anorectal physiology, on clinical severity and on qol. this is a randomized control trial. patient physiology was studied with anorectal manometry and endoanal ultrasonography; clinical severity was assessed with cleveland and st. mark's scales, and qol with the faecal incontinence quality of life (fiql) and the euroqol's eq5d questionnaires. urinary incontinence (ui) was also evaluated by means of international consultation on incontinence (iciq) score. patients were randomized and assigned to k (control), bf+k, es+k or nm+k, given active treatment for a 3-month period, and then evaluated again with identical tests and parameters to identify changes.

Eligibility criteria:
inclusion criteria: * age higher than 18 * to be woman * have had incontinence episiodes at least from 6 month since the beginning of the study * have had incontinence episodes during the last month prior the beginning of the study * the patient is able to understand the nature and impliations of the study and, therefore, to decide her participation. exclusion criteria: * not meeting inclusion criteria * have very mild condition (wexner \<4) * to be unable to perform / understand the treatments properly * being pregnant * to have used treatmets for fecal incontinence within the last six months prior to the start of the study * if, at reserarcher's criteria, the patient has not the proper conditions to perform and finish the treatments.

Keywords: anorectal physiology therapies quality fo life
predictive and advanced analytics in emergency medicine - neurological deficits

Conditions: Artificial Intelligence; Resource Allocation; Neurologic Manifestations

Summary: future predictive modeling in emergency medicine will likely combine the use of a wide range of data points such as continuous documentation, monitoring using wearables, imaging, biomarkers, and real-time administrative data from all health care providers involved. subsequent extensive data sets could feed advanced deep learning and neural network algorithms to accurately predict the risk of specific health conditions. moreover, predictive analytics steers towards the development of clinical pathways that are adaptive and continuously updated, and in which healthcare decision-making is supported by sophisticated algorithms to provide the best course of action effectively and safely. the potential for predictive analytics to revolutionize many aspects of healthcare seems clear in the horizon. information on the use in emergency medicine is scarce. aim of the study is to evaluate the performance of using routine-data to predict resource usage in emergency medicine using the commonly encountered symptom of acute neurologic deficit. as an outlook, this might serve as a prototype for other, similar projects using routine medical data for predictive analytics in emergency medicine.


Eligibility criteria:
inclusion criteria: * female and male subjects * age ≥ 18 years exclusion criteria: - none
lemborexant treatment of insomnia linked to epilepsy

Conditions: Epilepsy; Sleep

Summary: the goal of this clinical trial is to assess whether lemborexant can improve sleep in patients with epilepsy.


Eligibility criteria:
inclusion criteria: * sleep-related focal epilepsy * contraception exclusion criteria: * changes in antiseizure medication 1 month before study protocol or during study protocol * concomitant medications per sunrise1 * individuals with hepatic impairment * female participants who are pregnant or breastfeeding * individuals with compromised respiratory function * individuals with a history of complex sleep-related behaviour * individuals with rare hereditary diseases of galactose intolerance such as galactosemia or glucose-galactose malabsorption * individuals with a history of dependence or tolerance - abuse, dependence, rebound insomnia * individuals with psychiatric disorders with abnormal thinking and behavioural changes, depression, or suicidal ideation * individuals with a diagnosis of narcolepsy
endothelial dysfunction and coronary artery spasm

Conditions: Coronary Vasospasm

Summary: non-obstructive coronary artery disease (nocad) frequently accounts for myocardial ischemia in women. endothelial dysfunction is a pathogenic factor in coronary spastic angina (csa). csa is an important cause of nocad diagnosed invasively by coronary angiography (cag). digital reactive hyperemia peripheral arterial tonometry (rh-pat) provides noninvasive evaluation of endothelial dysfunction. the investigators hypothesized that the fingertip rh-pat could predict the presence of csa in women.

outline of methods: rh-pat was measured in women with chest pain prior to cag. coronary spasm was diagnosed by intra-coronary acetylcholine (ach) provocation test. using flow-wire, we assessed coronary endothelial function by coronary blood flow increase in response to ach (ach-cbf) and coronary flow reserve was assessed by adenosine (ad-cfr).

Eligibility criteria:
inclusion criteria: * stable post-menopausal women complaining angina-like chest pain exclusion criteria: * severe valvular disease * hypertrophic cardiomyopathy * severe peripheral artery disease * uncontrolled hypertension * severe collagen diseases * acute coronary syndrome

Keywords: coronary vasospasm endothelium, vascular vasodilation hyperemia
an observer rating scale of facial expression can predict dreaming in propofol anesthesia

Conditions: Anesthesia; Propofol; Drug Effect

Summary: this study investigates correlation between dreaming in propofol anesthesia and an observer-rating-scale of facial expression after gastrointestinal endoscopy in adults. it also compares dreamers and non-dreamers in age, bmi, propofol dose, duration of procedure, mean arterial pressure, pulse values and bispectral index values.

after ethical committee approval and written informed consent was obtained, a total of 124 patients undergoing gastrointestinal endoscopy were recruited in the prospective observational study. anesthesia was maintained using incremental propofol doses until the patient was calm and unresponsive to painful stimuli. bispectral index (bis), blood pressure (bp) and pulse were monitored in typical intervals: before induction, during induction, at the beginning of the procedure, at 2nd, 5th and 10th minute of the procedure, and on emergence. on the emergence of anesthesia, the patient's facial expression was rated numerically (-3 pain, +3 smile). thereafter patients were asked to rate their dream.

Eligibility criteria:
inclusion criteria: * consecutive patients undergoing gastrointestinal endoscopy at osijek university hospital form september 2016 to october 2017. exclusion criteria: * . patients who were younger than 18 years, unscheduled patients who were not hemodynamically stable, those who were not able to understand study protocol, and who did not sign written informed consent were not included in the study. patients whose procedure was longer than 60 minutes and patients with incomplete records were excluded from the study.

Keywords: propofol; endoscopy, gastrointestinal; dreams; facial expression; smiling
enteral nutrition and immune proteins study

Conditions: Healthy Adults

Summary: eligible healthy adults who consent to take part in the study will be randomised to receive either a specialised milkshake for all of their normal daily diet (exculsive enteral nutrition, een) or the same specialised milkshake for half of their normal daily diet (partial enteral nutrition, pen) for seven days. this randomisation is to prevent any bias. in the week before the allocated diet starts participants will be asked to give a weight and height measurement, blood sample, collect a stool and urine sample, and complete a food diary of everything they eat and drink using household measurements (e.g., a teaspoon) seven, four, and one day before the randomly allocated diet begins. participants will also be asked to give a weight measurement, blood sample, and collect a stool and urine sample before they start the allocated diet. all participants will be asked to collect a third stool, urine, and blood sample and weight measurement at the end of the seven days dietary intervention. blood samples collected during the study will be used to find out how the cells and proteins which instruct the immune system change during the special milkshake diet. stool and urine samples will be used to measure the levels of different bacteria which naturally live inside the gut and how their behaviour might have changed during the diet. those allocated to have pen will be asked to complete a second set of food diaries for three days during your seven days of specialised milkshake.


Eligibility criteria:
inclusion criteria: * healthy adults (\>/= 18 years) exclusion criteria: * those sufferring from acute or chronic illness (defined as illness which requires regular visits to health services) * those who have experienced weight changes +/- 2kg in the past month. * previous gut surgery, * use of antibiotics or steroids in the past month * food allergies which prevent consumption of the enteral nutrition used (milk protein allergy) * current pregnancy or breastfeeding.
resistance training and cardiometabolic risk

Conditions: Metabolic Syndrome

Summary: little is known on the effects of resistance training (rt) alone in individuals with metabolically healthy obesity (mho) and metabolically unhealthy obesity (muho). the present study aimed to examine the impact of rt on body composition, physical performance, lipid-lipoprotein profile, inflammation, and glucose-insulin homeostasis in 51 sedentary, postmenopausal women categorized as mho vs muho, according to the karelis and rabasa- lhoret classification or a single-phenotype adiposopathy approach (the plasma adiponectin (a)/leptin (l) ratio). participants followed a 4-month weekly rt program of 3 non-consecutive days of 6 exercises of major muscle groups (3 sets of 10 repetitions at 80% 1-rm).

several studies have examined mho individuals' responses to weight loss interventions. caloric restriction decreases body weight and body fat, notably visceral fat accumulation, of both mho and muho pre- and postmenopausal women, although changes in muho women are usually more important. in addition, while insulin sensitivity of muho women increases after a 12-week diet, it is significantly worsened in postmenopausal mho women. in this regard, previous works have shown discordant data of interventions including physical activity on the cardiometabolic risk and more particularly, insulin sensitivity. indeed, diet or aerobic training alone or combined aerobic and resistance training (rt), in men and postmenopausal women yielded promising results as insulin sensitivity increased in both muho and mho participants, with greater changes in the muho groups. however, the heterogeneity of the population (analysis without considering sex differences) as well as the type and duration (3 to 6 months) of different interventions make it difficult to generalize these results. as an example, insulin sensitivity was improved in muho men and women, while it remained unchanged in mho participants after a 9-month intervention combining diet and exercise. moreover, a 14-week community-based aerobic exercise program increased participants' cardiorespiratory fitness and reduced the number of metabolic syndrome components of mho men and women. however, to the best of our knowledge, no study has compared yet the impact of a rt program on muho and mho individuals.

Eligibility criteria:
inclusion criteria: * cessation of menstruation for more than 1 year and a follicle-stimulating hormone level ≥ 30 iu/l * sedentary for at least 3 months (\< 2 h/week of structured exercise) * non-smokers * free of known inflammatory diseases * no use of hormone replacement therapy * body mass index ≥ 30 kg/m2 * low to moderate alcohol consumption (\< 2 drinks/day) exclusion criteria: * history of cardiovascular disease * type 2 diabetes * orthopedic limitations.
providing mental health precision treatment

Conditions: Depression; Addiction; Anxiety; Sleep Disturbance

Summary: this research study is being conducted to understand if patients benefit from mobile health interventions while waiting for in-clinic mental health treatments, and to understand which patients receive the most benefit.

initially, results-reporting was planned for 12-month data. however, following 6-week data collection, the participants received other care, so the decision was made to report on the 6-week data.

Eligibility criteria:
inclusion criteria: * must have a scheduled mental health intake appointment at michigan medicine outpatient psychiatry or university health service at the university of michigan * must have daily access to a smartphone version that is compatible with study activity trackers. * understands english to enable consent and use of the mydatahelps app and app-based interventions * provide complete, updated contact information upon enrollment to the study * agree to be contacted by study staff during the study * willingness to keep study setup (devices, apps, settings) in required configuration for the duration of the study, and following instructions by study staff if required to update or re-achieve required configuration if required configuration has been lost (e.g., change of phone, app deletion) exclusion criteria: * self-reported or medical record indication of a current eating disorder * scheduled outpatient mental health appointment is a pediatric appointment (even if age 18+) * wrist too large or too small to wear an apple watch or fitbit comfortably (note: bands that are shorter or longer than the standard will be made available to minimize this exclusion)

Keywords: behavioral health precision health