Inclusion Criteria:  ASA (American Society of Anesthesiologists) class I-II The operation time between 60-180 minutes  Exclusion Criteria:  Severe cardiac disease COPD (Chronic Obstructive Pulmonary Disease) Severe liver and kidney disease, Diabetes mellitus Morbid obesity Alcohol and/or drug addiction Risk or history of malignant hyperthermia Pregnancy and lactation Emergency cases Operation time less than 60 minutes and longer than 180 minutes