Inclusion Criteria:  Age equal or over 18 and under 90 years old. Confirmed COVID-19 positive diagnostic through PCR. Radiological image compatible with non-cardiogenic bilateral pleuropulmonary exudate. Patient has received anti-viral and anti-inflammatory therapy.  Present any of the following clinical-functional criteria:  Respiratory distress: Tachypnea> 30 breaths / minute Partial arterial oxygen pressure (PaO2) / Fraction of inspiration (FiO2) ≤ 300 mmHg Signed informed consent, directly or delegated.  Exclusion Criteria:  Severe liver dysfunction (Child Pugh ≥ 3 or AST> 5 times normal) Severe renal dysfunction with glomerular filtration <30 mL / minute or under treatment with hemodialysis or peritoneal dialysis. Poorly controlled hypertension (BPs> 160 mmHg or TAd <100 mmHg) or having a history previous hypertensive crisis or hypertensive encephalopathy. History of poorly controlled heart disease with a NYHA> 2. History of thrombosis in the previous 6 months. Signs of active bleeding. Open wounds, gastrointestinal perforation. Diagnosis of thrombophilic diseases or hemorrhagic diathesis. Active viral hepatitis or HIV not properly treated. Intolerance or allergy to bevacizumab or its components. Pregnancy.