Inclusion Criteria:  Specimen collected/handled prior to enrollment in accordance with site policies and procedures. Specimen with adequate volume (approximately 300 µL) to complete protocol tests. Specimen is leftover BM from routine flow cytometry laboratory testing for plasma cell disorders, other hematological disorders, non-hematological tumors, and other hematological disorders (non-malignant). Specimen from a newly diagnosed or relapsed subject. Specimen is stored at room temperature, upon receipt by the site. Age of specimen (time of collection to start of first pre-wash): ≤24 hours. Specimen collected in EDTA (K2 or K3) or heparin (sodium or lithium). Specimens are from subjects irrespective of race, gender, and ethnicity.  Exclusion Criteria:  Specimen from healthy subject. Specimen from subject <22 years old. Specimen from subject undergoing any treatment for any form of L&L. Specimen from subject with minimal residual disease (MRD) as determined by site. Visibly clotted specimen. Visibly hemolyzed specimen. Frozen specimen. Refrigerated specimen. Fixed specimen.