A. Inclusion Criteria:  Age 18-60yrs Both genders Documented CP for at least 3 years Capable and willing to provide informed consent  B. Exclusion Criteria:  Acute exacerbation of pancreatitis Pancreatic malignancy On anti-depressant and antipsychotic medications Concomitant psychiatric illness (other than depression) Pancreatic malignancy Major co-morbidities Pregnancy and lactation