Inclusion Criteria:  Adult patients (aged >18 years) with an indication for percutaneous closure of PFO due to cryptogenic stroke, with indication validated by a cardio-neurological team. patients must provide written informed consent patients must be affiliated to a social security regime or be a beneficiary thereof.  Exclusion Criteria:  Patients under legal protection Patients not affiliated to any social security regime Patients within the exclusion period of another clinical trial as per the national registry of research volunteers