Inclusion Criteria:  Patients or the ones next to them who gave informed consent. Age ranges from 34 to 97 years. Patients undertake particular stroke therapy including endovascular treatment intravenous thrombolysis.  Exclusion Criteria:  Impaired strength of muscles because of cognitive and orthopedic diseases. Patients with severe hepatic, and/or renal diseases. Patients with impaired cognition and memory problems. Patients whose consent was not given by themselves, their caretakers.