Inclusion Criteria:  Diagnosis of Parkinson's disease according to UK Parkinson's disease society barin bank clinical diagnostic criteria Holds a validated Medical cannabis license, from Israeli Ministry of health Able to sign informed consent Age 18-80  Exclusion Criteria:  Use of Medical cannabis in the previous 30 days prior to study recruitment visit Concomitent severe co-morbidities able to influence outcomes such as spinal injury, cancer, dementia. Cannot sign informed consent