Inclusion Criteria:  Age >18 years, Confirmed diagnosis of SLE or IgA nephropathy, First half of the menstrual cycle, after the end of bleeding, Signed informed consent to participate in the study.  Exclusion Criteria:  Lack of menstruation, Pregnancy, Active infection requiring parenteral or topical antibiotic therapy within 2 weeks before examination, Neoplastic disease of the reproductive tract.