Inclusion Criteria:  age ≥ 3 months able to give informed consent (or parent/guardian able to give informed consent) a clinicopathological diagnosis (or differential diagnosis) of inherited bone marrow failure syndrome or related disorder (IBMFS-RD) as per the study team  Exclusion Criteria:  A clinicopathological diagnosis of an acquired bone marrow failure syndrome (including acquired aplastic anaemia and hypoplastic myelodysplastic syndrome) as per the study team Existing definitive genomic diagnosis for patient's haematological phenotype