Inclusion Criteria:  Able to provide Informed Consent in English and Spanish. Male and Female Subjects > 18 years of age may participate with no predetermined quotas or ratios for gender participation. Presenting to urologist or urogynecologist in outpatient setting with a history of complicated UTI (cUTI) and clinically suspected active UTI (e.g., UA positive for L.E. or nitrites) and based on clinical judgment require microbial testing. Definition of cUTI- UTI is considered complicated when the individual has one or more risk factors that predispose to higher treatment failure and poor outcomes6. These poor outcomes include persistence of UTI, increasing severity, or occurrence of complications such as urosepsis, recurrence, and perinephric abscess. Recurrent UTI is defined as 2 infections in 6 months or 3 infections in 12 months in a calendar year. A UTI at the index visit may be used towards this count.  Exclusion Criteria:  Patients with bladder/urologic cancer Patients presenting with chronic pelvic pain Patients presenting with untreated overactive bladder (either neurogenic or non-neurogenic) Patients not meeting incl. criteria listed above. Do not provide written informed Consent with HIPAA authorization form Inability to independently provide symptom data Patient must have email access to participate and complete in online surveys Pregnancy Incarceration If the provider deems that a urine culture/ Guidance UTI is not necessary in clinical management, the patient is not eligible for enrollment.