Inclusion Criteria:  - Moderate to severe atopic dermatitis  Exclusion Criteria:  Premature birth (under 37 weeks gestation) Severe medical condition (such as epidermolysis bullosa or ichthyosis) at time of enrolment that would complicate assessment for AD or preclude the use of investigational tools, or other major health problems (especially genetic or metabolic) that would have implications for neurodevelopment Any medical condition requiring the using of sedating medications (eg antihistamines)