Inclusion Criteria:  Over 20 years old Patients with postinflammatory hyperpigmentation for more than 3 months.  Exclusion Criteria:  Patients with topical hydroquinone, oral tranexamic acid and/or other skin whitening agents. Patients that receive or planning to receive laser treatment for spot removal during the study period. Individuals with allergic history to cysteamine or vehicle ingredients. Pregnant patients or patients planning to become pregnant during the time of the study.