Inclusion Criteria:  Patients receiving active treatment (surgery, chemotherapy [including immunotherapy or hormone therapy], radiation therapy) for a malignancy at a study cancer center >= 18 years old Clinically significant depression (Patient Health Questionnaire-9 (PHQ-9) >= 10 with at least one cardinal symptom > 1)  Access to smartphone, tablet, or computer with internet access; to short message service (SMS); or landline  Patients who do not have a smartphone will be offered assistance in obtaining a free smartphone through the government-sponsored Lifeline Phone Program for low-resourced individuals  Exclusion Criteria:  Advanced cancer or other condition that limits remaining life expectancy to less than 9 months Is solely receiving long-term hormone treatment for cancer Already engaged in or needing immediate specialty mental health care (i.e., acutely suicidal, carries a diagnosis of bipolar disorder or schizophrenia) Inability to speak and read English