Inclusion criteria  undergone neoadjuvant chemotherapy HER-2 or triple negative breast cancer clinical stage T1-3, N0-1, M0 (AJCC 8th) not Inflammatory breast cancer  neoadjuvant chemotherapy should be done before surgery(sandwich method is not allowed)  least four times anthacycline or taxane-based regimens no axilla lesion progression during chemotherapy no period of adverse response during chemotherapy undergone anti HER-2 therapy in HER-2 positive patient no preoperative anti hormonal therapy no preoperative radiation therapy did not axillary lymph node biopsy before neoadjuvant chemotherapy physical examination expected complete remission. And radiological expected Tumor size ≤ 2cm or non-mass enhancement ≤ 4cm no previous axilla surgery no previous ipsilateral breast surgery for invasive cancer no Pregnancy-associated breast cancer ECOG performance status 0-1 Serum or urine b-HCG negative agree to the consent form 20≤Age<70  Exclusion criteria  During pregnancy major depression or taking psychiatric medication significant psychiatric disorder or history of taking antipsychotic drugs any other lymph node metastasis than axillary lesion undergoing total mastectomy do not agree to the consent form