Inclusion Criteria:  Age 19~54 years in healthy volunteers 19 kg/m^2 ≤ BMI < 28 kg/m^2, weight(men) ≥55kg / weight(women) ≥45kg 90 mmHg ≤ SBP <140 mmHg, 50 mmHg ≤ DBP <90 mmHg agrees that the person, spouse, or partner uses appropriate medically recognized contraception and does not provide sperm or eggs from the date of administration of the first investigational drug to 7 days after the administration of the last investigational drug. Subjects who voluntarily decides to participate in this clinical trial and agree in writing to ensure compliance with the clinical trial  Exclusion Criteria:  Presence of medical history or a concurrent disease that may interfere with treatment and safety assessment or completion of this clinical study, including clinically significant disorders in digestive system, neuropsychiatric system, endocrine system, liver, cardiovascular system Subjects who judged ineligible by the investigator