Inclusion Criteria:  all patients were newly diagnosed with gastric cancer; all patients were pathologically diagnosed; all patients had pre-treatment coagulation test; stage I-IV disease; age≥18 years  Exclusion Criteria:  accompanying or secondary to other tumors; had history of venous thrombosis or received any anti-coagulation treatment; acute infection or intravascular disseminated coagulation; pregnancy or lactation; history of neoadjuvant chemotherapy; Lost to follow-up