Inclusion Criteria:  Being a woman between the ages of 18 and 45; Have been well informed about bariatric surgery and perioperative risks and have benefited from a multidisciplinary evaluation by a multidisciplinary team (RCP) ; Have a BMI greater than or equal to 40 kg/m2 or greater than or equal to 35 kg/m2 with at least one co-morbidity that can be improved after surgery (cardiovascular disease, sleep apnea and severe respiratory disorders, type 2 diabetes, osteoarticular diseases) Have been informed of the research on the samples taken during care; Having stated its decision not to object to the research on the samples taken during the treatment; To have accepted medical and surgical follow-up for 24 months; Patient under the general social security system.  Exclusion Criteria:  Being a pregnant or nursing woman; Being a type 1 diabetic; Have inflammatory bowel disease; Have severe and unstable eating disorders ; Have severe, uncontrolled cognitive, mental or psychological disorders; Have a cancerous pathology; Be addicted to alcohol and psychoactive substances (both legal and illegal); Have a life-threatening illness in the short or medium term; Have contraindications related to surgical operations in general such as general anaesthesia; Be under legal protection measures (guardianship, curators, safeguarding of justice), and person deprived of liberty.