Inclusion Criteria:  Patients undergoing elective solitary SAVR with bioprosthesis Patients who are in sinus rhythm and not taking any anti-arrhythmic medication, other than beta-adrenergic blocking agents, at the time of surgery In treatment with HMG-CoA reductase inhibitors in the past 3 months and of at least 7 days Age >60 years Willingness and provision of informed consent to be randomized  Exclusion Criteria:  Prior history of atrial fibrillation Prior history of cardiac surgery Hepatic dysfunction (Alanin-aminotransferase more than twice the upper limit) Creatinine >200 µmol/L