Inclusion Criteria:  women aged 20-40 oligomenorrhea or amenorrhea BMI 18-30 regular menstruation written consent obtained  Exclusion Criteria:  Hypothalamic amenorrhea, pituitary amenorrhea and ovarian amenorrhea Patients with uterine fibroids, adenomyosis, uterine malformation and endometrial polyps Patients with uterine artery embolization History of endometrial hyperplasia Irregular menstruation Patients with severe complications Patients with hypoovarian function