Inclusion Criteria:  Presence of 5mm or more peri-implant pockets Not having periodontal treatment in the last 3 months, The informed consent form must be approved, At least 18 years old.  Exclusion Criteria:  Presence of systemic disease, Smoking, Regular use of non-steroidal anti inflammatory drugs, Having been treated with antibiotics in the last 3 months, Individuals in need of pre-treatment antibiotic prophylaxis, Pregnancy and lactation, Not approving the informed consent form, Patients with known allergies.