Inclusion Criteria (Sythesis: 10;10;10;100):  ≥ 18 and <70 years Performance status, ECOG 0-1 Histologically proved adenocarcinoma in colon or rectum. BRAF wild-type CRC on primary tumor or liver metastases High standard oncological surgical resection of the primary tumor Liver metastases not eligible for curative liver resection confirmed by the validation committee At least one line (3 months) of chemotherapy No signs of extra hepatic metastatic disease or local recurrence on CT, MRI and Pet-CT within 4 weeks prior to the faculty meeting at the transplant unit Before start of chemotherapy no lesion should be larger than > 10 cm Objective response according to RECIST 1.1 or SD at two consecutive CT without CEA increase Patient with less than 10% response on chemotherapy may be included if they obtain al least 20% response after TACE (DEB-IRI) or by 90Y-spheres At least 10 months time span from CRC resection and date of being listed on the transplantation list. Satisfactory blood tests Hb >10g/dL, neutrophils >1.0, Bilirubin<2 x upper normal level, AST, ALT<5 x upper normal level, creatinine and albumin in normal level. CEA<100 ng/ml Signed informed consent and expected cooperation of the patients for the treatment and follow up  Exclusion Criteria:  Weight loss >10% the last 6 months Patient BMI > 30 Participation refusal General contraindication to LT Prior extra hepatic metastatic disease or primary tumor local relapse. Other malignancies in the previous 5 years Pregnancy or breast feeding Any reason why, in the opinion of the investigator, the patient should not participate.