Inclusion Criteria:  Patients ≥18 years of age at the time of consent; Histological confirmed melanoma (patient must have primary cutaneous melanoma with Breslow thickness ≥ 0.8-2.0mm with or without ulceration or <0.8mm with ulceration (pT1b - pT2b, AJCC 8th edition)); Indication for wide local excision (margin 1 cm) and SLN procedure; Patients should be willing and able to provide informed consent.  Exclusion Criteria:  Intolerance/hypersensitivity to 99mTc-nanocolloid, PB, iron or dextran compounds; Iron overload disease; Pregnant or breast-feeding women; Previous surrounded lymph node surgery; Patients with head and neck melanomas; Standard MRI exclusion criteria; Implantable (electrical) devices (e.g. pacemaker, cochlear implants, neurostimulator); Any other metal implants; Claustrophobia; MR-incompatible prosthetic heart valves; Patients who are unable or refuse to provide informed consent.