Inclusion criteria:  Age >18 years  Cancer survivors exposed to the following therapies:  high-dose anthracycline or high dose radiotherapy in thoracic wall low-dose anthracycline or anti-human Epidermal growth factor Receptor-type 2 drugs (anti-HER2) alone plus ≥ 2 CVRF and / or age ≥ 60 years at cancer treatment low-dose anthracycline followed by anti-HER2;  Cancer survivors with medical background of  coronary artery disease moderate valvular disease LVEF <50% Follow up after primary treatment with curative intent Conclusion of primary treatment at least 2 months before the inclusion  Exclusion criteria:  Previous participation in a CRP  Contraindications to exercise training:  musculoskeletal or neurologic disorders, cognitive impairment unstable angor pectoris, decompensated HF, active myocarditis, acute endocarditis, acute pulmonary thromboembolism, complex ventricular arrhythmias Active cancer Considered unsuitable as per principal investigator judgment (namely due to expected inability to fulfill proposed schedule)