Inclusion Criteria:  Signed informed consent in a language understandable to the participant prior to any study-mandated procedure. Women of childbearing potential must have a negative serum pregnancy test at screening, a negative urine pregnancy test on Day -1, and agree to consistently and correctly use a highly effective method of contraception. Women of non-childbearing potential. Body mass index of 18.0 to 35.0 kg/m2 (inclusive) at Screening Negative SARS-CoV-2 reverse transcription polymerase chain reaction test on Day -1.  Additional inclusion criteria for participants with severe renal impairment  Estimated glomerular filtration rate (eGFR) at screening using the Modification of Diet in Renal Disease formula less-than 30 mL/min/1.73 m2 for participants with renal impairment. The eGFR value should be confirmed on Day -1. Systolic blood pressure (SBP) 100 to 180 mmHg, diastolic BP (DBP) 50 to 105 mmHg, and pulse rate 60 to 100 bpm (inclusive), on Day 1 pre-dose. Stable concomitant medications for at least 3 weeks prior to screening and up to Day 1. Aspartate aminotransferase and alanine aminotransferase above the upper limit of normal. Clinically relevant findings in clinical laboratory tests (hematology, clinical chemistry, and urinanalysis) except for those related to renal impairment at Screening and on Day-1.  Additional inclusion criteria for control participants  eGFR at Screening using the Modification of Diet in Renal Disease formula of ≥ 90 mL/min/1.73 m2. SBP 90 to 139 mmHg, DBP 60 to 89 mmHg, and pulse rate 60 to 99 bpm, measured on the same arm, after 5 min in the supine position at screening and on Day 1 pre-dose.  Exclusion Criteria:  Pregnant or lactating women. Participation in a clinical study involving study treatment administration within 3 months prior to screening or participation in more than 2 clinical studies within 1 year prior to Screening. Previous exposure to cenerimod. Known hypersensitivity to any excipients of the treatment formulation. Clinically relevant abnormalities on a 12-lead electrocardiogram at Screening and Day -1. Previous treatment with anti-arrhythmic medications of class Ia or III within 2 weeks or 5 half-lives, whichever is longer, prior to study treatment administration. History or clinical evidence of any disease and/or existence of any surgical or medical condition, which might interfere with the absorption, distribution, metabolism, or excretion of the study treatment except for renal disease, appendectomy, herniotomy, or cholecystectomy. Aspartate aminotransferase and alanine aminotransferase above the upper limit of normal. Legal incapacity or limited legal capacity at Screening.  Additional exclusion criteria for participants with severe renal impairment:  Presence of severe cardiac disease. End-stage renal disease that requires dialysis. History of severe renal artery stenosis. Serum potassium concentration > 5.5 mmol/L. Presence of unstable diabetes mellitus. Strict fluid restriction. Clinically relevant findings in clinical laboratory tests (hematology, clinical chemistry, and urinalysis) except for those related to renal impairment at Screening and on Day -1.  Additional exclusion criteria for control participants  Clinically relevant findings on the physical examination at Screening. Clinically relevant findings in clinical laboratory tests.