Inclusion Criteria:  Signed informed consent Age >18 Patient suitable for 68Ga-PSMA PET/CT re-staging according to clinical practice (Previous radical prostatectomy with histological result of Prostate adenocarcinoma +/- postoperative prostate bed radiotherapy (adjuvant or salvage setting), with a biochemical relapse defined as a PSA > 0.2 and <1  Exclusion Criteria:  ADT administration within 6 months from study enrollment Persistent elevation of PSA after RP measured within 16 weeks from surgery (> 0.1 ng/ml)