Inclusion Criteria:  Age≥18 ST-segment elevation myocardial infarction was defined according to the universal definition of myocardial infarction STEMI treated by pPCI  Exclusion Criteria:  Patient with heart failure in admission STEMI with symptom-onset-to-balloon time>24h pPCI was not successful or only underwent coronary angiography Killip class ≥II in admission