Inclusion Criteria:  Mild essential hypertensive patients (BP ranged from 130/80 to 159/99 mmHg). Ability to undergo Study procedures. Willingness/ability to provide informed consent.  Exclusion Criteria:  Participants with secondary hypertension. Participants suffering from diabetes mellitus, coronary heart disease, peripheral vascular disease, acute or chronic liver disease, renal insufficiency, malignancies, infectious disease, or using non-steroidal anti-inflammatory drugs, steriods, vasoactive agents. Known allergies to niacin or nicotinamide. Receiving certain concurrent supplements. Women who are currently pregnant or who wish to become pregnant over the course of the study follow-up or who are at suckling period. Unwillingness/inability to provide informed consent.