Inclusion Criteria for Patients:  Patient(s) over 18 years of age Patient(s) capable of providing informed consent Use or possible use of ICSI for oocyte insemination At least 6 mature oocytes at time of insemination via ICSI  Exclusion Criteria for Patients:  Patient under 18 y/o Patients not capable of providing informed consent Use of IVF for insemination Less than 6 mature oocytes at time of rertrieval Anonymous donor sperm source Surgically retrieved sperm Sperm sample not sufficient for use with ZyMot device  Inclusion Criteria for Donors:  Donor(s) over 18 years of age Donor(s) capable of providing informed consent Use of ejaculate sperm, fresh or frozen, for insemination Sufficient sperm for use of ZyMot  Exclusion Criteria for Donors:  1. Anonymous donors