Inclusion Criteria:  men and women at the age of 18 or older acute kidney injury according to KDIGO-guidelines The patient (or his/ her authorised representative) is in the position and willing to give informed consent.  Exclusion Criteria:  Patients, who received kidney transplantation Patients on chronic dialysis at the time of enrolment Patients who are placed in an institution by judicial or governmental order Pregnancy Infection with HI- or Infektionen mit HI- oder Hepatitis virus infektion Participation in a clinical study with testing on drugs or medical devices (according to German Medicines Law or Medicinal Devices Act)