Inclusion Criteria:  Symptomatic chemotherapy-induced oral mucositis Need for oral topical therapy for symptomatic treatment Absence of other chronic oral disorders Properly obtained written informed consent Age of 18 years or older Patient is willing to use the Bocaliner™ device for 2 weeks No concurrent use of medications modulating pain  Exclusion Criteria:  Chronic oral conditions other than chemotherapy-induced oral mucositis No informed consent Age of <18 Inability to place the device in his/her mouth and keep it in place for at least 10 minutes due to severe oral pain, large lesions, or any other reason Inability/unwillingness to wear Bocaliner™ for the study period Concurrent use of pain-modulating agents Individuals with known allergies to silicone materials Individuals with severe difficulties to communicate and understand