Inclusion Criteria:  Body mass Index (BMI) ≥28 kilograms per square meter (kg/m²), or ≥24 kg/m² and previous diagnosis with at least one of the following comorbidities: hypertension, dyslipidemia, obstructive sleep apnea History of at least one unsuccessful dietary effort to lose body weight  Exclusion Criteria:  Diabetes mellitus Weight change > 5.0% after diet and exercise control for at least 12 weeks before screening Have used or are currently using weight loss drugs within 3 months before screening History of pancreatitis Family or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN-2) History of moderate to severe depression，or have a history of serious mental illness Any lifetime history of a suicide attempt