Inclusion Criteria:  Clinical diagnosis of chronic ischemic heart disease Indications for cardiac surgery Stenosis of more than 75% of the trunk of the left coronary artery, or proximal stenosis of the anterior descending artery and/or stenosis of more than 75% of two or more coronary arteries  Exclusion Criteria:  The presence of organic heart defects of rheumatic and infectious etiology; Acute myocardial infarction; Less than 3 months after acute coronary or cerebrovascular events; Severe pulmonary hypertension not associated with mitral regurgitation (above 75 mmHg); Contraindications for operations with cardiopulmonary bypass; Severe course of bronchial asthma, Chronic obstructive pulmonary disease in the acute stage; Refusal of the patient or relatives to participate in the study.