Inclusion Criteria:  - Patients with symptomatic benign prostatic hyperplasia deemed eligible for thulium laser enucleation of prostate.  Exclusion Criteria:  patients with history of prostatitis, patients with history of neurogenic detrusor overactivity (as determined after urodynamic observation), patients diagnosed with prostate cancer, patients who underwent previous surgeries of the lower urinary tract, patients with indwelling catheter, patients with history of nephrolithiasis, patients with known or suspected hypersensitivity to Phenolmicin P3 and/or Bosexil patients experiencing occurrence of severe intraoperative complications.