Inclusion Criteria:  Patients must have histologically or cytologically confirmed recurrent or metastatic solid tumours. Patients must have disease progression on the last treatment exposed to, have exhausted available approved lines of therapy or better-characterized therapies that, at the discretion of the investigator, is felt to be more appropriate therapy, or have malignancies for which there are no approved therapies. For the dose-expansion phase of the study, only those patients with the following tumour types will be permitted to enroll: transitional cell bladder cancer, pancreaticobiliary adenocarcinomas, gynecologic cancers (ovarian, cervical, endometrial), and lung adenocarcinoma. Four weeks must have elapsed since prior chemotherapy, hormonal therapy, targeted therapy, or radiation therapy. There is no restriction in the amount of bone marrow previously radiated. Recovery to baseline or grade 1 for all drug-related toxicities due to prior chemotherapy, radiation, hormonal therapy, or molecular targeted therapy, except for alopecia. Age ≥18 years. Eastern Cooperative Oncology Group (ECOG) Performance Status (PS) ≤1. Life expectancy of greater than 12 weeks.  Patients must have normal organ and marrow function as defined below:  absolute neutrophil count ≥ 1,500/mcL hemoglobin ≥ 90 g/L platelets ≥ 100,000/mcL total bilirubin ≤ 1.5 X upper limit of normal (ULN) AST(SGOT) and ALT(SGPT) ≤ 2.5 X ULN (≤ 5 X ULN in the presence of liver metastases) Creatinine (Cr) ≤ 1.5 X institutional upper limit of normal Cardiac ejection fraction by echocardiogram must be >50% at baseline. Any structural changes found must be reviewed by study doctor and deemed acceptable and safe prior to study enrolment. Any noted cardiac fibrosis will exclude a patient. The effects of CCI-001 on the developing human fetus are unknown. For this reason, women of child-bearing potential and men must agree to use adequate contraception; see Section 8.7) prior to study entry, for the duration of study participation and for 12 months after receiving the final dose of study drug. Should a woman become or suspect she is pregnant while participating in this study, she should inform her treating physician (Investigator) as soon as possible. Ability to understand the purpose of the study and the willingness to sign a written informed consent document. Patient must have measurable disease according to Response Evaluation Criteria in Solid Tumours (RECIST) 1.1 criteria. Signed written informed consent form for this trial.  Exclusion Criteria:  Patients may not be receiving any other investigational agents, chemotherapy, immunotherapy, radiotherapy, or molecular targeted agents within 28 days prior to enrollment to study unless discussed with the Principal Investigator. Patients may not have symptomatic central nervous system (CNS) metastasis. Patients with treated CNS metastasis are eligible, provided their disease is radiographically stable over a period of ≥ 8 weeks, asymptomatic, and they are not currently receiving corticosteroids and/or anticonvulsants. Screening of asymptomatic patients without a history of CNS metastasis is not required. History of allergic reactions attributed to compounds of similar chemical or biologic composition to CCI-001. The presence of grade 2 or higher peripheral neuropathy due to prior medical condition (such as multiple sclerosis), medications, or other etiologies. Any psychological, familial, sociological, or geographical conditions that do not permit medical follow-up and compliance with the study protocol. Uncontrolled intercurrent illness, including but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements. Pregnant or nursing women. Human Immunodeficiency Virus (HIV)-positive patients. Hepatitis B- and/or C-positive patients. History of other invasive cancer within 2 years of study entry. The exceptions are in situ cervical cancer, basal cell carcinoma or squamous cell carcinoma of the skin, and localized prostate cancer after curative therapy such as surgery, or radiation (Gleason score ≤ 7). For these exceptions, all treatment must have been completed 6 months prior to enrollment. Patients taking warfarin. Low-dose or therapeutic dose of heparin or low-molecular weight heparin are allowed. Cardiac fibrosis on echocardiogram.