Inclusion Criteria:  Male and female patients, 18 years of age or older Confirmed diagnosis of PDAC or GI tract adenocarcinoma metastatic to liver Scheduled for imaging with contrast enhanced CT  Exclusion Criteria:  Inability to tolerate intravenous contrast medium All liver metastases ≤ 10 mm in maximal diameter on the contrast enhanced CT used for comparison to the planned research ultrasound Multiple confluent liver metastases or tumor burden > 50% of the liver as estimated by a radiologist