Inclusion Criteria:  Patients undergoing allogeneic stem cell transplantation Patients develop aGVHD The count of neutrophilia cells over 0.5 * 109/L, hemoglobin over 60 g/L, platelet over 30 *109/L Signed informed consent  Exclusion Criteria:  Unsuitable to the study due to severe complication such as uncontrolled severe infection Claustrophobia Ear diseases such as otitis media Eye diseases such as glaucoma Epilepsy history Important organ dysfunction Coagulopathy