Inclusion Criteria:  Male and female. Adults between 18 and 60 years of age. BMI ≥ 30 and ≤ 50 kg/m2.  Exclusion Criteria:  Patients with any type of diabetes. Patients with high blood pressure. Patients with acquired diseases secondarily producing obesity and diabetes. Patients who have suffered a cardiovascular event. Patients with gastrointestinal diseases. Weight loss > 3 kg in the last 3 months. Catabolic diseases such as cancer and acquired immunodeficiency syndrome. Pregnancy status. Positive smoking.  Drug treatment:  Antihypertensive drugs or treatment Treatment with hypoglycemic agents or insulin and antidiabetic drugs. Treatment with statins, fibrates or other drugs to control dyslipidemia. Use of antibiotics in the three months prior to the study. Use of steroid drugs, chemotherapy, immunosuppressants, or radiation therapy. Anorexigenic or that accelerate weight loss such as sibutramine or orlistat. Supplements with any of the functional foods used in the study. Probiotic, prebiotic or symbiotic supplements.