Inclusion Criteria:  Adult patients over 20 years of age Patients undergoing cardiac surgery using cardiopulmonary bypass (CPB)  Exclusion Criteria:  pregnant women and minors the patients who required mechanical life support as followings due to unstable vital signs after CPB weaning, ECMO (ExtreCorporeal Membrane Oxygenation) IABP (Intraaortic ballon pumping) such as continuous renal replacement therapy (CRRT)