Inclusion Criteria:  Healthy adult subjects who signed informed consent BMI of >18.0 kg/㎡ and <30.0 kg/㎡ subject, weight more than 50kg(45 kg or more for woman)  Exclusion Criteria:  Subjects participated in another clinical trial within 6 months prior to administration of the study drug Inadequate subject for the clinical trial by the investigator's decision Subjects participated in another clinical trial within 6 months prior to administration of the study drug