Inclusion Criteria:  Male or female 75 years of age or older, Lymphoid hemopathies (diffuse large cell B-cell lymphoma (DLBCL), follicular lymphoma, marginal zone lymphoma, Hodgkin's lymphoma and T-cell lymphoma, chronic lymphocytic leukemia (CLL)) or plasma cell and/or lymphoplasmacytic hemopathies (multiple myeloma or Waldenström disease). WHO performance index 0-3, Patients requiring first or second line chemotherapy and/or immunotherapy associated or not to targeted therapy, Patients with a life expectancy of more than 3 months, Persons affiliated or benefiting from a social insurance, Free, informed and written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research).  Exclusion Criteria:  Myeloid hemopathies, Patient included in a clinical trial that potentially interferes with the purpose of the study (geriatric interventional study, early drug study), Patient under court protection, guardianship or curatorship