Inclusion Criteria:  Adult aged > 18 years Patient understands and has signed the consent form. Patient has an angiographically documented chronic total occlusion (i.e. estimated to be >3 months duration) showing distal TIMI 0 flow. Occlusion with absence of antegrade flow through the lesion and with a presumed or documented duration of 3 months. Suitable candidate for non-emergent PCI Left ventricle ejection fraction > 25%  Exclusion Criteria:  Patient unable to give informed consent. Current participation in another study with any investigational drug or device. Known or suspected contrast allergy. in-stent CTO. Planned treatment of a second CTO during the index procedure Intolerance to Aspirin and/or inability to tolerate a second antiplatelet agent (Clopidogrel or Prasugrel or Ticagrelor). Recent major cerebrovascular event (history of stroke or TIA within 1 month) Renal insufficiency (serum creatinine of > 200μmol/L) Active gastrointestinal bleeding Active infection or fever that may be due to infection Life expectancy < 2 years due to other illnesses Significant anaemia (haemoglobin < 10.0g/L) Severe uncontrolled systemic hypertension (> 240 mmHg within 1 month of procedure) Severe electrolyte imbalance Congestive heart failure [New York Heart Association (NYHA) Class III\IV] CSA Class IV. Unstable angina requiring emergent PCI or coronary artery bypass graft (CABG) Recent myocardial infarction (MI) (within the past one week) Unwillingness or inability to comply with any protocol requirements Subject is pregnant or nursing. Female subjects of child-bearing potential must have a negative pregnancy test done within 7 days prior to the index procedure per site standard test. Extensive prior dissection from a coronary guidewire use Drug abuse or alcoholism. Patients under custodial care. Bleeding diathesis or coagulation disorder Kawasaki's disease or other vasculitis