Inclusion Criteria:  Patients aged 19 years old or older, with American Society of Anesthesiologists Physical Status 1-3, and scheduled for general anesthesia  Exclusion Criteria:  Patients scheduled for liver surgery Uncontrolled hypertension Uncontrolled diabetes mellitus Liver disease Kidney disease Intolerance or hypersensitivity to benzodiazepine Addiction Glaucoma Heart failure Peripheral vascular disease Obstuctive lung disease Patients scheduled for regional anesthesia before general anesthesia Pregnancy