Inclusion Criteria:  Cancer Patients  18 years of age and older. Scheduled to receive any kind of therapy in our center. Performance status of ECOG 0, 1, 2, or 3. Able to understand QoL questionnaire.  Normal (non cancer) controls  18 years of age and older healthy volunteers. Without a history of cancer except for cured skin cancer, without any active cancer. ECOG Performance status 0, 1, 2, or 3.  Exclusion Criteria:  Participants who have supposedly limited ability to complete the survey questionnaires of the present study will be excluded.