Inclusion Criteria:  Consistent with the diagnosis of congenital hyperinsulinemia with ineffective diazine; With the maximum dose of diazine at 15mg/kg/d for 5 days, fasting blood glucose/postprandial blood glucose could not be stabilized at the target value of 3.3mmol/L without intravenous glucose infusion. patients treated with octreotide subcutaneous injection.  Exclusion Criteria:  Before the diagnosis of CHI and the treatment related to CHI, the child had received total pancreatectomy without octreotide Secondary hypoglycemia caused by diseases other than CHI Patients who refused to take octreotide due to parents or family economic reasons, but not hospital treatment factors. Patients who intervene/interfere with octreotide treatment regimen for parental reasons