Inclusion Criteria:  Individuals infected with HIV in the stable phase of their disease (absence of disease outbreak and absence of therapeutic modification within 3 months before inclusion), Subject with ongoing HIV follow-up on an outpatient basis (outpatient or day hospital consultation) in the participating center, and having virological suppression at the threshold of 50 copies / mL for at least 5 years (tolerance of blips < 200 copies / mL during this period) Aged ≥ 55 at baseline CD4 + T cell nadir> 200 / mm3 Giving free and informed written consent Being affiliated with or benefiting from a social security scheme.  Exclusion Criteria:  Persons treated with antibiotics, probiotics, prebiotics or any other treatment that may disrupt the gut microbiota within two months before stool sampling. Subject not followed regularly in the participating center, Subject only coming for full hospitalization Subject in the primary infection phase of less than 1 year