Key Inclusion Criteria:  Adults, 18 years or older Live in the United States Meet diagnostic criteria for Gorlin Syndrome Willing to avoid application of a non-study topical medication to the face (prescription or over the counter) during the study. Willing to forego treatment of BCCs with anything other than the study medication except when the Investigator believes that delay of treatment of a BCC potentially might compromise the health of the subject. During the trial, the only allowed form of BCC treatment is surgical. Participant will be encouraged to use their preferred sunscreen with a sun protector factor (SPF) of at least 30 daily  Key Exclusion Criteria:  Recently participated in a clinical trial evaluating an investigational product for the treatment of BCCs or Gorlin Syndrome within 3 months prior to to starting study medication. Participant can start the study screening period prior to completing the 3 month washout. Recently used topical or systemic (oral) treatment that might interfere with the evaluation of the study medication.