Inclusion Criteria:  BMI between 18 and 25 kg/m² Non-smoker Written informed consent  Exclusion Criteria:  Cardiovascular risks Metabolic diseases (e.g. diabetes) Use of antibiotics, anti-fungi or anti-parasites in the last 3 months or during participation in the study Use of prebiotics and / or probiotics in the form of supplements in the 7 days preceding the start of the study (greater than or equal to 100000000 Colony Forming Units or organisms per day) Taking drug treatment for chronic pain management (paracetamol, vasodilator, homeopathy, aspirin greater than 500 mg per day) Simultaneous participation in another research involving the human person or having recently participated in another research for which the exclusion period has not been completed.