Inclusion Criteria:  At least 1 middle cerebral artery aneurysm confirmed by imaging (CTA/MRA/DSA); Accept endovascular intervention or middle cerebral artery aneurysm clip craniotomy, regardless of whether there is a clinical symptoms; Multiple aneurysms, whether usual treatment, but it requires the treatment time interval to > 6 months; The subjects currently has independent life ability, namely the mRS score 3 points or less; The patient or family agreed to sign a consent form.  Exclusion Criteria:  Patients with other intracranial vascular malformations, such as AVM and AVF; Fusiform, traumatic, bacterial or dissecting aneurysm; Ruptured middle cerebral artery aneurysm associated with intracranial hematoma; Intracranial or other parts of the patients with malignant tumors; General condition is bad, is expected to survival time less than 1 year or poor body condition, can't tolerate anesthesia or aneurysm surgery patients; Involved with other intracranial aneurysm patients clinical research; A hospital surgery clip or endovascular treatment of patients at the same time; Refused to follow-up of patients.