Inclusion Criteria:  Age 18 years or over Symptomatic necrotic collection diagnosed on MRI or CT abdomen/pelvis (seen as a fluid collection in the setting of documented pancreatic necrosis that contains necrotic material and encased within a partial or complete wall) Necrotic collection of any size with ≥ 33% of solid/necrotic component and any number of loculations, located within the pancreatic/peri-pancreatic space Necrotic collection visualized on EUS and amenable to EUS-guided drainage  Exclusion Criteria:  Age < 18 years Females who are pregnant Necrotic collection that is not amenable for EUS-guided drainage Irreversible coagulopathy (defined as INR >1.5, thrombocytopenia with platelet count < 50,000/mL) Use of anticoagulants that cannot be discontinued for the procedure Unable to obtain consent for the procedure from either the patient or LAR