Inclusion Criteria:  Self-identified Hmong persons whose both parents are Hmong, with and without hyperuricemia (serum urate (UA) ≥ 6.8 mg/dL ) and/or gout (defined by 2020 American College of Rheumatology Guideline for the Management of Gout) are eligible for the study. For those with gout, participants qualify if they have serum UA ≥ 6.8 mg/dL based on the baseline measurement or serum UA < 6.8 mg/dL based on the baseline measurement with at least 1 episode of peripheral joint or bursal swelling, pain, or tenderness (acute gout flare) in their lifetime, (with or without urate-lowering therapy)  Exclusion Criteria:  Allergy or sensitivity to vitamin C  Diagnosis/history of:  Gastrointestinal surgery including colectomy, ileectomy, and gastrectomy Inflammatory bowel disease Auto-immune disease Type I diabetes mellitus Severe kidney disease (i.e., on dialysis) End-stage liver disease (i.e. cirrhosis) Glucose-6-phosphate dehydrogenase deficiency, (due to increased bleeding risk in those with G6PD deficiency when receiving vitamin C) Pregnant or breastfeeding persons  Current use of:  Antibiotics Probiotics supplement Ketogenic diet