Inclusion Criteria:  Age between 18 and 80 years; First corneal transplant surgery; Capable of providing informed consent; Capable of administering eye medication or access to a caregiver able and willing to administer the eye medication for the patient.  Exclusion Criteria:  Active ocular infection; Past corneal transplant (any technique); Advanced glaucoma or macular disease; Active or latent systemic infection (tuberculosis, histoplasmosis, coccidioidomycosis, cytomegalovirus, pneumocystis, aspergillosis or hepatitis B); Malignancy diagnosed in the past 5 years (any kind); Demyelinating disease; History or current diabetes mellitus (controlled or uncontrolled) or heart failure (New York Heart Association class III or IV); Pregnancy or breastfeeding; Allergy to infliximab or to a compound of its topical formulation; Significant anomaly of complete blood count or hepatic enzymes; Current or anterior use of anti-TNF-α medication or other anti-inflammatory biologics.