Inclusion Criteria:  Age ≥ 80 Scheduled for surgery under general anesthesia with indication for rapid sequence induction American Society of Anesthesiologists physical status classification (ASA) I to IV Informed consent (see appendix 1) Body mass index (BMI) < 35 kg/m2 Read and understand Danish  Exclusion Criteria:  Neuromuscular disease Known allergy to rocuronium and/or suxamethonium Known hyperkalemia > 5 mM Previous malignant hyperthermia Known homozygote plasmacholinesterase gene mutation variant a or s Known impaired kidney function defined as estimated glomerular filtration rate (eGFR) < 30