Inclusion Criteria:  age ≥18 years;  confirmed histologic diagnosis of HGS-EOC or high grade endometrioid tumor; presence of one FFPE primary tumor biopsy with at least 40% of tumor cells based on Hematoxylin and Eosin staining, in the archive of the Pathology Departments of the hospital centers where they have been treated; presence of one or more Pap Tests sampled up to eight years before EOC diagnosis during routine cervical cancer screening; negative history for other gynecologic malignancies;  Exclusion Criteria:  pap test not available in patients with ovarian cancer