Inclusion Criteria:  Patient volunteering to participate in the study. Patients eligible for participation in the ARMOR trial (current head and neck cancer patient trial conducted at Penn Dental Medicine[PDM]) Non-contributory medical history (Patient can be seen for dental appointment in PDM). No history of previous endodontic treatment on the tooth/teeth selected for treatment. Asymptomatic and vital teeth with deep decay (Irreversible pulpitis due to decay reaching pulp).  Exclusion Criteria:  Economic status, gender, race or ethnicity are not of concern for the proposed investigation and therefore for study exclusion. Patients will not be eligible to participate in the study if any of the following exclusion criteria applies:  Symptoms or necrotic tooth with presence of periapical radioluceny. History of previous endodontic treatment on the teeth to be treated. Teeth affected by fractures. Compromised periodontal status with pockets exceeding 4 mm, exceeding mobility I or gingival edema). At the discretion of the PI, patient is unlikely or unwilling to follow study requirements.