Inclusion Criteria:  Healthy, adult, male or female (of non-childbearing potential only), 18-55 years of age, inclusive, at the screening visit. Must follow protocol specified contraception guidance. Continuous non-smoker who has not used tobacco/nicotine-containing products for at least 3 months prior to the first dosing based on subject self-reporting. Body mass index (BMI) ≥ 18.0 and ≤ 32.0 kg/m2 at the screening visit. Medically healthy with no clinically significant medical history. Able to swallow capsules. Understands the study procedures in the informed consent form (ICF), and be willing and able to comply with the protocol.  Exclusion Criteria:  Presence of systemic or severe infection. History or presence of a significant medical condition or disease which is not completely resolved. History or presence of alcohol or drug abuse History or presence of hypersensitivity or reaction to the study drug or related compounds. History of tuberculosis. Presence of any fever within 2 weeks prior to first dosing. Females able to have children. Females who are pregnant or lactating. Presence of HIV. Must be able to refrain from using any drugs, including prescription and non-prescription medications beginning 28 days prior to the first dosing. Lactose Intolerance. Donation of blood or significant blood loss or blood transfusion within 56 days prior to the first dosing. Plasma donation within 7 days prior to the first dosing. Participation in another clinical study within 30 days prior to the first dosing.