Inclusion Criteria:  OSA met the diagnostic criteria of obstructive sleep apnea in the United States Classification of Sleep Diseases in 2014 Between the ages of 18 and 80, regardless of gender Sign informed consent  Exclusion Criteria:  previously diagnosed patients with heart failure, coronary artery disease, valvular disease, cardiomyopathy, arrhythmia, chronic obstructive/ restrictive pulmonary disease, thyroid dysfunction (including hypothyroidism or hyperthyroidism), already treated with CPAP, poor image quality of echocardiography.