Inclusion Criteria:  patients aged ≥18 years; ECG/Holter diagnosis of AF; Previous stroke or systemic thromboembolic complications; High risk of thromboembolic complications - CHA2DS2-VASc Score ≥ 2; HASBLED score of > 2; Contraindications to oral anticoagulation or Complications of oral anticoagulation;  (8) Acceptable surgical candidate, including use of general anesthesia; (9) patient adherence to the study and patient Informed Consent Form has been signed  Exclusion Criteria:  No ECG with AF recorded (12-lead ECG, Holter recording, external event recorder or implantable loop recorder) or only atrial flutter recorded, Significant valve disease or coronary multivessel artery lesions requiring operation; Stroke/cerebrovascular accident (CVA) within previous 30 days; Critical preoperative state; participation in a clinical trial patient refusal  Registry imposes intraoperative exclusion criteria to otherwise enrolled patients:  Presence of thrombus in the LA or LAA LAA tissue with significant adhesions (as evaluated by the surgeon) making AtriClip® placement overly risky. Previous cardiac operations (e.g., CABG, heart transplant, valvular replacement) making LARIAT placement overly risky. Patients with a previous atrial septal defect with surgical or transcatheter closure making Watchman placement overly risky. NYHA IV; Right-sided heart failure; Symptomatic carotid artery disease; active systemic infection.