Inclusion Criteria:  Informed consent Age: 19-60 year-old women Plan of myomectomy for uterine leiomyomas Leiomyoma Subclassification System 2-7 (robot-assisted laparoscopic myomectomy is possible) American Society of Anesthesiologists Physical Status classification 1 or 2 A person who understands the contents of the clinical trial, is cooperative with the trial, and is judged to be able to participate until the end of the study  Exclusion Criteria:  Pregnancy or breastfeeding A single diameter of uterine leiomyoma is greater than 12 cm or more or multiple leiomyomas with more than five Suspicious disease of uterine malignancy Patient with has a history of pelvic surgery (cesarean section, myomectomy, etc.) and is expected to have severe pelvic adhesion A person who is hypersensitive or contraindicated to vasopressin A person who is hypersensitive or contraindicated to tranexamic acid Considered as inappropriate by the researcher's judgment