Inclusion Criteria:  The subject is aged over 20 years old. The subject was diagnosed as bladder pain syndrome/interstitial cystitis subject with lower urinary tract symptoms, such as frequent urination, urgent urination, bladder pain, etc.  Exclusion Criteria:  The subject is aged under 20 years old. Pregnant women. The subject with congenital disorders of the urinary tract. The subject with a urinary tract infection or tumor.