Inclusion Criteria:  15 years of age or older HIV-positive Group 1: At least one symptom of TB  Group 2:  Advanced HIV disease (CD4 count less than 200cell/µl or clinical stage III/IV) No signs and symptoms of TB Signature of the informed consent  Exclusion Criteria:  Intake of anti-tuberculosis drugs for more than 5 days in the month prior to the consultation except preventive TB treatment. Decline to sign informed consent.