Inclusion Criteria:  - Maternal Age 18 - 35 years. Gestational age first trimester of pregnancy (between 5-13 weeks). Missed abortion confirmed by ultrasound. Singleton pregnancy. Normal uterus and cervix on clinical examination. Cervix is not dilated. No vaginal bleeding.  Exclusion Criteria:- Evidences suggesting start of spontaneous abortion and previous trial to induce abortion.  Presence of uterine contraction or bleeding, Multi-fetal pregnancy. Suspicion of septic abortion. History of Previous cervical surgery or manipulation. Ex: cervical tear , cervical cauterization . Uterine anomaly. Presence of IUD( intrauterine device) in situ Underlying medical diseases.Ex:diabetes mellitus,hypertension History of allergy or adverse effects to vaginally administered medication e.g. isosorbide -5- mononitrate Those unwilling to participate in the trial Higher order cesarean section(more than three