Inclusion Criteria:  > 18 years of age or older. Patients attending cardiology, pulmonology, endocrinology or rheumatology programs at the centers participating in the study. Patients with vaccination information available and confirmed in the medical records (in addition it will be confirmed at the time of the interview during the study enrollment consultation). Patients who sign the informed consent approved for this purpose.  Exclusion Criteria:  Patients with a diagnosis of CAP prior to 90 days from the time of enrollment in the study. Patients admitted to hospital during the 7 days prior to enrollment in the study. Patients with any clinical or manifest limitation to provide biological samples.