Inclusion Criteria:  Diagnostic of non-specific low back pain Aage from 18 to 65 Last for at least 12 weeks VAS between 4 and 7 No other treatment in the past 3 months Patients with no partial skin damage No other relevant treatment methods Sign informed consent and informed consent  Exclusion Criteria:  Pregnant women Suffer from diabetes With skin ulcers or contusion wounds Past history of severe allergy to transdermal preparations Complicated with serious diseases