Inclusion Criteria:  Control group: will consist of healthy adult non-obese volunteers (BMI 18.5 to 23.0 kg/m2), age 25 to 45 y, of any gender who accept to participate in the study by signing the informed consent. Obese group: will consist of adult obese (BMI ≥ 35.0 kg/m2) patients, age 25 to 45 y, of any gender, and will be recruited from the outpatient Clinic of Obesity at the INCMNSZ  Exclusion Criteria:  At the time of recruitment, none of the participants will have diagnosis of the following: type 2 diabetes (controlled or not), hypertension, liver or kidney failure, metabolic syndrome, taking antinflammatory drugs or dietary supplements, and in the case of women, pregnant or lactating