Inclusion criteria  Age ≥ 18 years old Preoperative histologically proven adenocarcinoma of the upper, middle or lower part of the stomach. Advanced disease (Staged cT2-T4a, N0-3;M0 according to 8th edition of the AJCC TNM Staging System) at diagnosis, in which resection can be safely achieved by distal or total gastrectomy with D2 lymphadenectomy via a minimally invasive (laparoscopic or robotic) approach, either as first treatment or after neoadjuvant treatment No distant metastasis, no direct invasion of pancreas, spleen or other organs nearby in the preoperative and intraoperative examinations Written informed consent  Exclusion criteria  Women during pregnancy or breast-feeding History of previous upper abdominal surgery (laparoscopic cholecystectomy will be allowed) History of previous gastrectomy, endoscopic mucosal resection or endoscopic submucosal dissection History of allergy to iodine agents Cancer located at the esophago-gastric junction (Siewert I, II, III tumors 29) Patients candidates to transthoracic esophagectomy, transhiatal extended gastrectomy or proximal gastrectomy History of previous neoadjuvant chemotherapy (except perioperative chemotherapy for gastric cancer) or radiotherapy