Inclusion Criteria:  Being in the first 24 hours of admission to the PICU Internal reasons for hospitalization with children No co-morbid disease Hospitalization in PICU during data collection procedure  Exclusion Criteria:  Hospitalization just before the study The children who is not available for wiping bath Hospitalized children after surgical procedures Antibotic use during the study Being chlorhexidine gluconate allergy history Impaired skin integrity (burns, skin disease etc.) Use of antibiotics, probiotics or steroid-containing immune system suppressing agents at last two months Radiotherapy or the chemotherapy patients Severe septic shock The children with tracheostomy, PEG, permanent dialysis catheter etc.