Inclusion Criteria:  Single household (not sharing the same concession with other households) with children under SMC coverage (aged 3-59 months) with at least one child under 35 months of age, Household members residing within the HDSS catchment area, Willingness of roommates to be screened and treated, Ability to complete the study follow-up period, Written consent obtained from parents/guardian Written consent/assent obtained from roommates  Exclusion Criteria:  Household with children under SMC coverage who did not receive the SMC (Amodiaquine-Sulfadoxine-Pyrimethamine) or sharing the same concession with other households Household with children under SMC coverage but at least one of his/her roommates refuse to be screened and treated (these children will still receive the SMC treatment as part of their routine malaria prevention policy) Severely ill individual at the time of enrolment including severe malaria, Known allergy to AQSP for children and DHAPPQ for roommates Planned travel or inability to complete the study follow-up, Participation to malaria vaccine trial Unwillingness to participate to the study.