Inclusion criteria:  Male and female participants between 18 and 80 years old Written informed consent  Exclusion criteria:  Age younger than 18 years or older than 80 years Participants with somatic or mental comorbidities, especially malignant tumor diseases, cardiac insufficiencies > NYHA II, severe depressive episodes, psychosis or dementia Pregnancy or breast feeding Addictions to alcohol, medications or drugs (except tobacco) An existing legal guardianship Participation in another scientific study within the previous eight weeks before enrollment Restless Legs Syndrome patients with one of the following secondary predispositions: iron deficiency, polyneuropathy, prolapsed disk, spinal stenosis or chronic obstructive pulmonary disease