Inclusion Criteria:  Is at least 18 years of age and has full legal capacity to volunteer; Has read and signed an information consent letter; Is willing and able to follow instructions and maintain the appointment schedule; Habitually uses ocular lubricants or artificial tears to relieve symptoms of dryness at least once per day for the past 30 days;  Has dry eye disease as per the TFOS DEWS II definition:  DEQ-5 ≥ 6 or OSDI ≥ 13 PLUS at least ONE of the following signs in at least one eye:  i. NITBUT < 10 seconds ii. >5 spots of corneal fluorescein staining OR > 9 conjunctival spots iii. Lid wiper fluorescein staining ≥ 2mm length ≥ 25% width.  Exclusion Criteria:  Is participating in any concurrent clinical or research study; Has worn any contact lenses in the past 30 days; Has previously, or currently uses I-DROP MGD eye drops; Has any known allergy or intolerance to I-DROP MGD or Thealoz Duo eye drops; Has any known active* ocular disease (allergies or inflammation) and/or infection; Has a systemic condition that in the opinion of the investigator may affect a study outcome variable (e.g. uncontrolled autoimmune disease or uncontrolled immunodeficiency disease); Has a history of sensitivity to rapidly blinking lights or photosensitive epilepsy as one of the a key assessment device employs rapid blinking lights; Is using any systemic or topical medications that in the opinion of the investigator may affect a study outcome variable (e.g. antihistamines); Has known sensitivity to sodium fluorescein to be used in the study; Self-reports that they are pregnant, lactating or planning a pregnancy at the time of enrolment; Has a undergone ocular surgery in the past 6 months; Uses warm compress therapy, unless performed regularly, for a minimum of 30 days, and maintained at the same frequency throughout the duration of the study; Unwilling to stop using their habitual ocular lubricants or artificial tears after Visit 2 (start of Part II); Has been fitted with punctal plugs within 30 days prior to Screening; Is a member of the Centre for Ocular Research & Education directly involved in the study;  Has taken part in another clinical research study within the last 30 days.  For the purposes of this study, active ocular disease is defined as infection or inflammation which requires therapeutic treatment. Mild (i.e. not considered clinically relevant) lid abnormalities (blepharitis, meibomian gland dysfunction, papillae), corneal and conjunctival staining are not considered active ocular disease. Neovascularization and corneal scars are the result of previous hypoxia, infection or inflammation and are therefore not active.