Inclusion Criteria:  Adult patient Obtainment of written informed consent Suspected newly or recurrent glioma (grade ≥ II) on MRI Patient eligible for surgery (biopsy or resection) Decision of surgery (biopsy or resection) at neuro-oncology interdisciplinary tumor board  Exclusion Criteria:  Rejection of consent by patient Hemoglobin < 7g/dl Rejection of surgery by patient Suspected grade I tumor on MRI