Inclusion Criteria:  Diagnosed with RR-TB Diagnosed with pulmonary TB (PTB) or PTB plus extra-pulmonary TB (EPTB) ≥18 years of age Able to sign informed consent Not on TB treatment at time of enrolment  Exclusion Criteria:  Patients diagnosed EPTB without pulmonary involvement Patients with TB Meningitis or TB of the bone. Has any condition that, in the opinion of the investigator or physician, would preclude provision of informed consent, make participation in the study unsafe, complicate interpretation of study outcome data, interfere with achieving the study objectives or compromise patient safety.