Inclusion Criteria:  Women aged 16-45 years Appropriate medical status for laparoscopic surgery (largest myoma ≤15 cm) Baseline hemoglobin ≥9 g/dl No contra-indications to the use of glyopressin or carbitocin Myoma-related symptoms, such as pelvic pressure or pain, menorrhagia, or infertility Not pregnant at the time of presentation (i.e., negative urine pregnancy test or last menstrual period within the last 4 weeks)  Exclusion Criteria:  Previous myomectomy History of bleeding disorders Concurrent anticoagulation therapy History of Uncontrolled ischaemic heart disease Any pelvic abnormalities requiring concomitant surgery Treatment with a GnRH agonist or ulipristal acetate within three months preceding surgery Inability to understand and provide written informed consent.