Inclusion Criteria:  Female participants must complete the Female Enrollment Form. Those subjects of childbearing potential must have a negative urine pregnancy within 36 hours of study drug administration and also agree to use one of the medically accepted methods of contraception listed on the form for a period of one month following the study. Female subjects of non-childbearing potential, defined as physiologically incapable of becoming pregnant, must meet the criteria listed on the Female Enrollment form, but are not restricted to the use of contraception following study participation. Participants must be able to sit upright for periods of 30 minutes. Participants should have a body mass index between 19 and 30 kg/m2 Initial post-resuscitation Glasgow Coma Scale score following blunt head trauma of 3 to 12 or coma (not due to sedation) greater than 6 hours. Emergence from Post-traumatic Amnesia as documented by serial administration of the Orientation-Log or Galveston Orientation and Amnesia Test Have an anticipated hospital length of stay of 5 days or more following screening and consent. Able to provide consent.  Exclusion Criteria:  Women who are pregnant or breast-feeding Persons who are known to be allergic to iodine Persons who have extensive soft tissue damage to the neck region, including carotid artery dissection, spinal cord injury, or other conditions, that makes lymphatic drainage techniques undesirable. Women who are of child bearing potential who do not agree to use medically acceptable contraceptives for one month following the study. Subjects who are participating in another interventional trial.