Inclusion Criteria:  History of at least two ankle sprains in the same leg, of which the first sprain is more than one year Leading to at least one interrupted day of desired physical activity The Cumberland Ankle Instability Tool (CAIT) ≦ 24 Slump test in ankle plantar flexion with inversion: positive  Exclusion Criteria:  Pregnancy Surgical treatments Previous fractures in either lower extremity Any concomitant lower extremity pathology, for example, vascular disease, osteoarthritis and rheumatoid arthritis Significant pain or injury to the lumbar or cervical spine Regular use of medication: anti-inflammatory drugs, painkiller, steroid or muscle relaxants Previous manual therapy or exercise interventions received on the lower extremity within the previous 3 months