Inclusion Criteria:  Age ≥ 18 years  All consecutive patients admitted to one of the participating medical centers emergency departments (ED) or at the intensive care unit (ICU) (see 4.1 Population Base) with clinical suspicion of acute intestinal ischemia, which is based on;  clinical manifestation; physical examination by the physician; laboratory measurements; physician's consideration to perform computed tomography (CT)-scan  Exclusion Criteria:  A subject who meets any of the following criteria will be excluded from participation in this study:  Age ≤ 18 years In order to evaluate the performance of the panel of markers for the acute intestinal ischemia in clinical practice, the study population must resemble the clinical patient population as closely as possible