Inclusion Criteria:  Patient with peripheral lung nodule less than 30mm on CT scan referred for biopsy Age ≥ 18 Written informed consent after participant's information  Exclusion Criteria:  Central lesion (visible on bronchoscope) or presence of metastatic lymph node (not requiring radial EBUS) Pure GGO lesion  Patients at increased risk of bleeding  Cannot stop agents such as antiplatelet agent or anticoagulant therapy Coagulopathy: Thrombocytopenia (< 100,000/mm3) or prolonged PT (INR > 1.5) Patient with existing or risk of pulmonary and cardiovascular decompensation Intolerance to sedation Vulnerable groups such as pregnant woman, breast feeding, etc. Previously diagnosed cancer patient who needs re-biopsy for genetic susceptibility