Inclusion Criteria:  Healthy male or female. Age 18-65 y. BMI between 18.5 kg/m2 and 40 kg/m2 (inclusive). Are willing to fast and not consume non-caloric stimulant for 10h before the assessments, and during the stay in the center. Are willing to avoid moderate or vigorous physical activity during 24h before the visits.  Exclusion Criteria:  Smoking or use of tobacco products within the last 3 months Diagnosed with diabetes. Previous bariatric surgery (or other surgeries) for obesity or weight loss. Use of medications affecting metabolism or sleep. History of neurological disease. History of cardiovascular disease, including hypertension, or other chronic diseases. Pregnant, planning to become pregnant, or breastfeeding Claustrophobia impeding to stay calm under a plastic canopy.