Inclusion Criteria:  1. Age ≥ 18 years 2. Hip arthroplasty requiring reoperation or revision with bone graft 3. Willing to provide informed consent. 4. For women of childbearing potential; a negative pregnancy test prior to reoperation.  Exclusion Criteria:  1. Patients with prosthetic joint infection as the reason for the reoperation 2. Known allergies and contraindications for the use of vancomycin or tobramycin 3. Mental inability, reluctance, or language difficulties that according to investigator judgement, result in difficulty understanding the meaning of study participation 4. Expected difficulties to complete 2-year follow-up 5. Women of child bearing potential not using contraception 6. Pregnant women 7. Nursing women