Inclusion Criteria:  Ability to cooperate with imaging procedures. Health status: established type 2 diabetes No history of panretinal photocoagulation (PRP) No history of treatment with intravitreal agents for past 12 months  Exclusion Criteria:  Previous or current malignancy Acute or chronic infection (HIV, hepatitis B or C, tuberculosis) Cerebral vascular accident or cerebral vascular procedure Current pregnancy History of organ transplantation Presence of a graft (to avoid any effect of the graft) History of previous vitrectomy Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.