Key Inclusion Criteria  Successful wearer of spherical soft contact lenses with at least 3 months wearing experience, with a minimum wearing time of 5 days per week and 10 hours per day. Possess spectacles and willing to wear habitual spectacles for vision correction when study lenses are not worn, as needed. Willing to wear contact lenses for at least 16 hours on one of the days (day prior to each week 1 visit). Other protocol-specified inclusion criteria may apply.  Key Exclusion Criteria:  Habitual PRECISION1, Clariti 1-Day, and DAILIES TOTAL1 contact lens wearers. Any monovision and multifocal lens wearers. Symptomatic subjects as determined using the symptomatology questionnaire. Other protocol-specified exclusion criteria may apply.