Inclusion Criteria:  Subject must provide written informed consent prior to any clinical investigation related procedure. At least 18 years of age. Referred for duplex ultrasound of the lower limb (s) with suspected or previous history of peripheral arterial disease Must have an ABPI performed as part of the assessment Able to obtain a brachial cuff blood pressure reading Must have a valid ankle duplex ultrasound measurement at the Posterior Tibial Artery (PTA) and Dorsalis Pedis Artey (DPA)  Exclusion Criteria:  Subject is currently participating in another clinical investigation or has participated in another clinical investigation in the past 30 days prior to the start of the present study; Pregnant or nursing subjects and those who plan pregnancy during the clinical investigation follow-up period Presence of other anatomic or comorbid conditions, or other medical, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements, or impact the scientific soundness; Inability or refusal to give informed consent Lower extremity wound or compromised skin of the legs that prevents access to the studied arteries