INCLUSION CRITERIA  Adults (≥18 years) Those living within larger cities of Pakistan (for laboratory access)  Those self-isolating at home within 5 days of the start of the illness with:  Clinical symptoms suggestive of COVID-19 (i.e. those who have at least one of the following symptoms: Respiratory symptoms, such as cough and shortness of breath; Fever; Muscle pain; Headache; Sore throat; New loss of taste or smell; Severe fatigue; Nausea or vomiting; Diarrhoea and Congestion or runny nose OR Those with virologically confirmed SARS-CoV-2 infection and clinical symptoms indicative of COVID-19 (as detailed in (a) above). Provision of informed consent  EXCLUSION CRITERIA  Onset of illness (symptoms) more than 5 days Inability to consent Age less than 18 years. Pregnancy Immunosuppressed patients Inability to perform HSNIG Those taking part in another interventional medical trial Those with suspected/confirmed COVID-19 in whom hospital admission is recommended Those who do not have access to email / internet Those living in a household with another person currently participating in this study Those who have not provided consent to take part