Inclusion Criteria:  Female patients aged twenty to sixty years old The American Society of Anesthesiologists (ASA) physical status classification grade I or II Scheduled for laparoscopic gynecological surgeries under general anesthesia.  Exclusion Criteria:  Patients who have gastrointestinal disorders, histories of PONV after a previous surgery, Renal or liver dysfunction, history of motion sickness, Have received any opioid, steroid, or antiemetic medication in the 24hs before surgery, and Pregnant or menstruating women.