Inclusion Criteria:  Any person admitted to CMCH as a Suspected thiamine deficiency related peripheral Neuropathy / Possible dry-beriberi:  Risk factors + at least 2 of the following signs:  Risk factors include Imbalanced diet (diet poor in thiamine/rich in carbohydrate or anti-thiamine factors), malnutrition, alcoholism, Gastrointestinal surgery, chronic diarrhoea, chronic vomiting, pregnancy or history of recent delivery, chronic. diuretics use, renal dialysis, total parenteral nutrition.  Muscle weakness of upper and or lower limb (less than grade 5 power in MRC scale) Positive sensory symptoms (burning, tingling or pain) Objective sensory deficit (pain, touch, position, vibration sense ) Absent or reduced deep tendon reflexes Positive squat test (unable to rise after squatting without help) Leg swelling Age 18 years and above.  Exclusion Criteria:  Patients with isolated cardiac/wet beriberi. Patient with known causes of peripheral neuropathy such as Diabetic, hereditary, Demyelinating (GBS, CIDP), metabolic (hepatic/renal impairment), drugs (e.g. Isoniazid, Ethambutol, Phenytoin, Metronidazole, Dapsone etc.) Toxin (As ,Organo-phosphate Compound (OPC), Pb ,Hg except alcohol) etc. Patients refuse to participate.