Inclusion Criteria:  Subjects that have provided written informed consent. Healthy males and females 18 to 65 years, both included, at the time of enrolment. Subjects who are able to provide cooperation and comply with dosing regimen. Women of childbearing age (from menarche) should submit a urine pregnancy test with a negative result at the time of enrolment in the trial.  Exclusion Criteria:  Simultaneous participation in another clinical trial. Females who are pregnant or breast-feeding, or potential pregnant or breast-feeding females. Subjects who are allergic to any of the components included in MV130. Subjects with any concomitant disease or treatment that, according to the investigator criteria, may affect the development of this study, such as immunodeficiencies, malignancies involving bone marrow or lymphoid systems, medical treatment affecting the immune system (including corticosteroids, immunosuppressants, biological agents,…), human immunodeficiency virus, - - Subjects who have been vaccinated (flu, pneumococcal or any other vaccine different from COVID-19 vaccine) within 6 months before inclusion, or who have planned to be vaccinated during the clinical trial (excluding the COVID-19 vaccine). Subjects who have had an infection that included fever and/or diarrhoea within 3 months before inclusion. Subjects under metformin treatment during the last month before inclusion in  Subjects under statins treatment during the last month before inclusion in the clinical trial or during *.  these drugs interfere with metabolic pathways involved in trained immunity induction