Inclusion Criteria:  Ability and willingness to give written informed consent Age 18 years or older at the time of informed consent Stable (non-emergent) typical or atypical symptoms suspicious for CAD (e.g., chest pain, chest tightness, chest burning, shoulder pain, palpitations, jaw pain, or non-chest pain symptoms such as dyspnea or worsening effort tolerance. Patients having undergone clinically-indicated invasive coronary angiography or coronary computed tomography angiography within one month before consent signature  Exclusion Criteria:  At Screening Visit 1:  Asymptomatic subjects Previous coronary revascularization (e.g., coronary artery bypass graft surgery, stenting) Subjects being evaluated for other cardiac diseases (e.g., valvular disease, cardiomyopathy) Pregnant or breastfeeding women  At Study Visit 2 or Ocular Exclusion Criteria:  Medium or high opacity of the lens Bleeding in vitreous Pupillary dilation inadequate or contraindicated Deficient visual fixation Refractive error outside of the range -15 to +15 Inability to obtain satisfactory images with the MHRC