Inclusion Criteria:  Clinical diagnosis of intrauterine twin pregnancy. The patients whose psychological screening scale score reached the critical value (pregnancy stress scale >50 and/or Self rating depression scale ≥ 40 and/or The self rating Anxiety Scale (SAS) was more than 50. The outpatient department of the research hospital was established and antenatal examination was carried out regularly. No mental and communication disorders (including depression and other mental diseases). Voluntary participation in this study  Exclusion Criteria:  Pregnancy complicated with severe physical diseases; Drop out of this study due to various reasons (including abortion, unwilling to participate in this study)