Inclusion Criteria:  Healthy as defined by:  the absence of clinically significant illness and surgery within 4 weeks prior to dosing. the absence of a clinically significant history of neurological, endocrine, cardiovascular, respiratory (except resolved childhood asthma), hematological, immunological, psychiatric (except including depression that has not required treatment for at least 6 months), gastrointestinal, renal, hepatic, and metabolic disease. Male or female, non-smokers or casual smokers (defined as smoking the equivalent of less than an average of 5 cigarettes per week over a 3 month period, and willing to abstain from smoking during involvement in the study and for 1 month prior to screening), ≥18 and ≤55 years of age, with BMI >18.0 and <32.0 kg/m2.  Females of childbearing potential who are sexually active with a male partner must be willing to use one of the following acceptable contraceptive methods throughout the study and for 30 days after the last study drug administration:  Simultaneous use of intrauterine device placed at least 4 weeks prior to study drug administration, and condom for the male partner; Simultaneous use of hormonal contraceptives started at least 4 weeks prior to study drug administration and condom for the male partner. Sterile male partner (vasectomized since at least 6 months).  Male subjects who are sexually active with a female partner of childbearing potential (childbearing potential females are defined as women that are neither post-menopausal nor surgically sterile) must be willing to use one of the following acceptable contraceptive methods from the first study drug administration until at least 90 days after the last study drug administration:  Simultaneous use of a male condom and, for the female partner, hormonal contraceptives used since at least 4 weeks, or intra-uterine contraceptive device placed since at least 4 weeks; Male subjects must be willing not to donate sperm until 90 days following the last study drug administration. Subjects with normal lung function defined as greater than or equal to 80% predicted forced expiratory volume in one second (FEV1). Males and females who are in same-sex relationships can be included. There are no mandatory contraceptive requirements for males or females in same-sex relationships. Male and female heterosexual subjects who practice abstinence from sexual intercourse as a usual and preferred lifestyle.  Part D only: Volunteers with mild asthma defined as:  Asthma diagnosed with appropriate medical documentation; FEV1 ≥70% predicted FEV1 and FEV1/FVC ratio ≥0.7 at screening; FeNO ≥35 ppb at screening; Well-controlled, or partly-controlled, by as-needed use of short-acting β2 agonists for at least 3 months prior to dosing; Reversibility test at screening consistent with diagnosis of asthma (≥12% and 200 mL increase in FEV1 over the baseline value). Capable of consent  Exclusion Criteria:  Any clinically significant abnormality at physical examination, clinically significant abnormal laboratory test results or positive test for HIV, hepatitis B, or hepatitis C found at screening or at check-in (Day -1, not applicable to serology assessments). Any clinically significant illness, infection, medical/surgical procedure, or trauma within 4 weeks of check-in, or planned inpatient surgery or hospitalization during the study period. Any history of malignancy or neoplastic disease (not including excised, non-recurrent, non-melanoma skin cancers). Positive urine drug screen, urine cotinine test, or alcohol breath test at screening or at check-in (Day -1). History of allergic reactions to LQ036, to any biologic therapy, or other related drugs, or to any excipient in the formulation. Positive pregnancy test at screening or at check-in (Day -1) Clinically significant ECG abnormalities or vital sign abnormalities (systolic blood pressure less than 90 or greater than 140 mmHg, diastolic blood pressure less than 40 or greater than 90 mmHg, or heart rate less than 40 or greater than 100 bpm) at screening. History of significant alcohol abuse within 1 year prior to screening or regular use of alcohol within 6 months prior to the screening visit. Regular use of alcohol is defined as greater than 14 units of alcohol per week, where 1 unit is defined as 100 mL of wine at 13.5% a/v, 375 mL of beer at 3.5% a/v, or 30 mL of spirit at 40% a/v. History of significant drug abuse within 1 year prior to screening or use of soft drugs (such as tetrahydrocannabinol) within 1 month prior to the screening visit or hard drugs (amphetamines, methamphetamines, methadone, barbiturates, benzodiazepines, cocaine, opiates, methylenedioxymethamphetamine, and phencyclidine) within 3 months prior to screening. Participation in a clinical research study involving the administration of an investigational or marketed drug or device within 30 days prior to the first dosing, administration of a biological product in the context of a clinical research study within 90 days prior to the first dosing, or concomitant participation in an investigational study involving no drug or device administration.  Use of medications for the timeframes specified below, with the exception of medications exempted by the Investigator on a case-by-case basis because they are judged unlikely to affect the PK profile of the study drug or subject safety (e.g., topical drug products without significant systemic absorption):  Prescription medications (except for hormonal contraceptives in all study parts and short-acting β2 agonists for patients in Part D) within 14 days prior to the first dosing; Over-the-counter products and natural health products (including herbal remedies, homeopathic and traditional medicines, probiotics, food supplements such as vitamins, minerals, amino acids, essential fatty acids, and protein supplements used in sports) within 7 days prior to the first dosing, with the exception of the occasional use of paracetamol/acetaminophen (up to 2 g daily), ibuprofen (up to 800 mg daily), and oral contraceptives; Depot injection or implant (except for hormonal contraceptives) of any drug within 3 months prior to the first dosing; Long-acting ß2 agonists for 4 weeks prior to screening; Anti-immunoglobulin E,anti-Interleukin-5, or anti-Interleukin-4 Receptor therapy for 6 months prior to screening; Inhaled corticosteroids (greater than 500 μg/day of beclometasone dipropionate or equivalent) within 16 weeks prior to screening, Oral or injectable steroids for the treatment of asthma or respiratory tract infection within 5 years prior to screening; Intranasal steroids within 4 weeks prior to screening; Topical steroids within 4 weeks prior to screening; Leukotriene antagonists within 2 weeks prior to screening; Anticholinergics or cromoglycate within 1 week prior to screening. Inhaled short-acting β2 agonists (such as salbutamol) within 6 months prior to screening (not applicable to patients in Part D). Donation of plasma within 7 days prior to dosing. Donation or loss of blood (excluding volume drawn at screening) of 50 mL to 499 mL of blood within 30 days, or more than 499 mL within 56 days prior to the first dosing. Breast-feeding subject. History of latent or active tuberculosis, or exposure to endemic areas within 8 weeks prior to QuantiFERON®-TB testing performed at screening. Positive QuantiFERON®-TB test indicating possible tuberculosis infection. Immunization with a live attenuated vaccine within 1 month prior to dosing or planned vaccination during the course of the study. Serious local infection (e.g., cellulitis, abscess) or systemic infection (e.g., septicemia) within 3 months prior to screening. History of clinically significant opportunistic infection (e.g., invasive candidiasis or one pneumocystis pneumonia). History of parasitic diseases (e.g., toxoplasmosis, cysticercosis, toxocariasis). History of frequent, recurrent herpes simplex. Presence of fever (body temperature greater than 37.6 °C) e.g., a fever associated with a symptomatic viral or bacterial infection, within 2 weeks prior to the first dosing. Life threatening asthmatic episode at any time in the past. C-reactive protein level above 5 mg/L. Any reason that, in the opinion of the Investigator, would prevent the subject from participating in the study.