Inclusion Criteria:  Evidence of a degenerative process Clinical Dementia Rating (CDR) score indicating mild cognitive impairment (CDR = 0.5), mild dementia (CDR = 1) through moderate dementia (CDR = 2)  Exclusion Criteria:  Subjects unable to give informed assent Cognitive decline clearly related to an acute illness Advanced terminal illness Any active cancer or chemotherapy Any other neoplastic illness or illness characterized by neovascularity or angiopathy Subjects previously taking plasmalogen supplementation prior to study enrollment