Inclusion Criteria:  Patients who are undergoing elective colorectal cancer surgery at Ramathibodi hospital both open and laparoscopic surgery. Both male and female who age between 15 to 70 years old. Physical status American Society of Anesthesiologists (ASA) classification1-2-3.  Exclusion Criteria:  Metastatic disease. Patients who reject to participate or withdrawal from the research. History of Mosapride allergy. Pregnancy. Emergency colorectal cancer surgery. Intestinal perforation or obstruction. Patients who have cardiac problem (Side effects of Mosapride may include arrhythmia or QTprolong). Physical status American Society of Anesthesiologists (ASA) classification 4-5.