Inclusion Criteria:  Adult (18-100 years)  Exclusion Criteria:  People with a compromised immune system Active treatment with chemotherapy HIV infection with cluster of differentiation 4 (CD4) count below 200/µl Combined immunodeficiency Treatment with methylprednisolone >16mg for more then 2 weeks Transplant patients Diagnosed Chronic Rhinosinusitis with Nasal Polyps Known pregnancy at the time of screening Inability to give informed consent or absence of legal representative who can give informed consent. Any contra indication for receiving the SARS-CoV2 vaccination