Inclusion Criteria:  Male and female, healthy volunteers aged 18-55 years, body mass index between 18.0 to 30.0 kg/m2. All of them should be able to complete the clinical study including the follow-up and capable of providing written informed consent.  Exclusion Criteria:  History serious hypersensitivity reactions History or evidence of clinically significant renal, hepatic, gastrointestinal Have high risk for coronavirus infection based on risk assessment questionnaire or diagnosed as confirmed case of COVID-19 History about administration of first dose or second dose of COVID-19 vaccine within 30 days prior to check-in in each Period History or evidence of family diabetes History or evidence of type 1 diabetes mellitus, diabetic ketoacidosis, diabetic pre-coma etc.