Inclusion Criteria:  Group I will include infertile patients with varicocele that is diagnosed clinically and by doppler scrotal ultrasonography. Group II will include infertile patients due to other causes than varicocele Group III will include fertile men with history of childbirth within the previous year.  Exclusion Criteria:  The patients will be excluded from the group I in the following conditions:  History or evidence of Genital tract infection. History or evidence of hormonal/chromosomal abnormalities. History or evidence of chronic debilitating diseases. History of hormonal treatment or chemotherapy. Low semen volume less than 1.5 ml. Severe oligozoospermia less than 5x10*6 /ml. Azoospermia.