Inclusion Criteria:  Patients with gastrointestinal symptoms related to FGID including functional constipation and/or infant colic diagnosed according to Rome IV criteria for clinical purposes. ≥ 37 weeks of gestation at birth. ≥ 2500 g of birth weight.  Exclusion Criteria:  Infants with failure to thrive (weight gain <100 grams/week on average from birth). Major medical problems (e. g. immunodeficiencies, developmental problems or genetic abnormalities) Gastrointestinal diseases Administered with antibiotics for 4 weeks or probiotics for 2 weeks before or during study