Inclusion Criteria:  Adult patients (over 18 years old) Suffering from acute infection by SARS-Cov2, diagnosed by PCR-real time, detection of viral antigen, specific antibodies with or clinical epidemiological criteria Hospitalization defined by attending or referral physician (severe or critical according to NIH)  Exclusion Criteria:  Patients under 18 years of age. Convalescent from acute SARS-Cov2 infection and without evidence of a new event reinfection. Outpatient management or hospitalization less than 24 hours for diagnosis and / or evaluation of severity or complications.