Inclusion Criteria:  Must be between the ages of 18 and 75 years Must be a patient undergoing screening or surveillance colonoscopy Must be able to understand and willing to sign an IRB-approved written informed consent document.  Exclusion Criteria:  Inability to provide informed consent. Personal history of colorectal cancer (CRC) Personal history of colon surgery or colon resection Personal history of Inflammatory bowel disease Personal history of familial polyposis Current pregnancy Active GI bleeding Colonoscopy exams where the cecum cannot be reached (randomization will occur after cecum is reached).