Inclusion Criteria:  Male or female age 9 or above. Clinical diagnosis of moderate to severe truncal acne based on IGA  Exclusion Criteria:  Known or suspected allergies or sensitivities to any components of the study drug. Any disorders that would preclude the use of tetracycline-class antibiotics or sarecycline. Any uncontrolled or serious disease, or any medical or surgical condition, that may either interfere with the interpretation of the trial results and/or put the subject at significant risk (according to the Investigator's judgment) if the subject takes part in the trial.  Other protocol defined Inclusion/Exclusion criteria may apply.