Inclusion Criteria:  Women between 40- 44-years undergoing ICSI cycle with FSH less than 15 and AMH more than 0.30.  Exclusion Criteria:  Azoospermia in male partner, Previous ovarian surgery, Severe endometriosis, Uterine cavity lesion Metabolic or endocrine disorders including hyperprolactinemia and ypo/hyperthyroidism. Previous failed ICSI cycle. BMI more than 30.