Inclusion Criteria:  Woman >18 years and < 80 years of age; Classified as Breast Imaging Reporting and Data System (BI-RADS) 4C or 5; Lesion depth is < 6 cm from skin surface; Non-palpable lesions; Informed consent obtained.  Exclusion Criteria:  Multicentric breast cancer; Pregnant or lactating; Known or suspected nickel-titanium allergy.