Inclusion Criteria:  Written informed consent Age ≥ 18 and ≤70 years Elective trauma surgery (arthroscopy, reconstructive foot surgery) under regional anesthesia (spinal anesthesia) with propofol, dexmedetomidine or without sedation Montreal cognitive assessment test ≥ 26 Patients with American Society of Anesthesiologists (ASA) I-II  Non-inclusion criteria:  Not written informed consent to participate in the research and/or perform regional blockade Age˂18 and ˃70 years Allergy to propofol, dexmedetomidine, lidocaine, bupivacaine Pregnancy Epilepsy anamnesis II-III degree atrioventricular block Montreal cognitive assessment test ˂ 26 Patients with American Society of Anesthesiologists (ASA) ˃ II Emergency operation The presence of psychiatric disorders Сancer patients with a life expectancy of less than two years Taking anticoagulants, psychotropic drugs  Exclusion Criteria:  Patient refuse from further participation Ineffective spinal anesthesia Allergy on anesthesia drugs during perioperative period