Inclusion Criteria:  Patient 18 years of age or older Patient who has completed bone growth Patient informed and willing to participate in the study Partially or totally toothless patient who will be implanted with the TBR® Bone Level implant(s) for the prospective cohort Patient implanted with the TBR® TISSUE LEVEL Z1 implant(s) before December 2009 for the retrospective cohort  Exclusion Criteria:  Pregnant or lactating women Patient with bone disease of the head and neck region Patient refusing to participate in the study Patient with at least one contraindication to implantation Patient on osteoporosis treatment with Biphosphonates or Denosumab.