Key Inclusion Criteria:  Male or female patients ≥18 years of age who are HLA-A*02+ Histologically confirmed incurable or metastatic solid tumors that are HPV16+ Cancer must have progressed after at least 1 available standard therapy for incurable disease, or the patient is intolerant to or refuses standard therapy(ies) or has a tumor for which no standard therapy(ies) exist Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 to 1 At least 1 measurable lesion according to RECIST 1.1 Must have a lesion that can be biopsied with acceptable clinical risk and agree to have a fresh biopsy at Baseline and on Cycle 2 Day 8 (+/- 3 days) Patients must agree to venous access for the blood draw and be willing to have a central line inserted if venous access is an issue Adequate organ function and bone marrow reserve performed within 14 days prior to the blood draw  Exclusion Criteria:  Treatment with anticancer therapy, including investigational therapy, within 2 weeks prior to blood draw. For prior therapies with a half-life longer than 3 days, discontinuation of the therapy must have occurred at least 28 days prior to Cycle 1 Day 1 Systemic treatment with either corticosteroids (>10 mg of prednisone or the equivalent per day) or other immunosuppressive medications within 14 days prior to Cycle 1 Day 1 Patients treated with non-corticosteroid based immunosuppressive agents within the last 6 months may not be eligible and should be discussed with the Sponsor Patients with active, known, or suspected autoimmune disease may not be eligible and should be discussed with the Sponsor Patients with >Grade 1 AEs related to previous treatment with anticancer or investigational therapy that do not resolve at least 2 weeks prior to blood draw, except Grade 2 alopecia Known active hepatitis B or hepatitis C, or active mycobacterium tuberculosis infection History of any Grade 4 immune-related AE (irAE) from prior immunotherapy Has known active central nervous system metastases History of interstitial lung disease requiring steroids Significant acute or chronic illness Major surgery within 2 weeks of blood draw