Inclusion Criteria:  Prostate cancer, non-metastatic Have been on ADT with long acting GnRH agonist continuously for last 3 months, AND planning to continue ADT for at least 6 months  Exclusion Criteria:  Used pioglitazone in last 6 months Heart Failure NYHA Class 3 or 4 Known to have osteoporosis at this time. history of bladder cancer Hemoglobin <8 g/dl eGFR <15 ml/min/1.73m2 liver enzymes (ALT or AST) >3 times the upper limit of normal