Inclusion Criteria:  Adults (21-70 years old) who have been diagnosed with oral dysplasia or that have been treatment-planned as wait and watch or Adults (21-70 years old) or who have been diagnosed with oral squamous cell carcinoma, or matched healthy controls free of any oral lesions  Exclusion Criteria:  Adults who have had a course of antibiotics that was completed less than 3 months prior to the study; Adults with any immunosuppressive condition or medication that would put the subject at risk of consuming daily probiotics; Adults who regularly use probiotic dietary supplements Adults that have alcohol/tobacco use history that does not match study population - this if for the healthy controls arm only.