Inclusion Criteria:  Females ≥ 18 years up to 85 years old Individuals referred to hospitals for diagnosis of breast cancer Availability of radiological images: 2D mammography or 2D synthetic digital tomosynthesis, ultrasound, or magnetic resonance Availability of pathological report (surgical specimen) Availability of (Neoadjuvant) treatment allocation (scheme, duration, benefit) Availability of treatment response  Exclusion Criteria:  Patient with incomplete or low-quality data (radiological, pathological or clinical)