Inclusion Criteria:  Healthy volunteers will be included in the study if they meet all of the following criteria at screening, and after check-in on Day -1, prior to dose administration:  Must have given written informed consent before any study-related activities are carried out and must be able to understand the full nature and purpose of the trial, including possible risks and adverse effects. Adult male and female volunteers, 18 to 50 years of age (inclusive). Subjects who smoke no more than 2 cigarettes or equivalent per week can be included in the study but must be willing to abstain from smoking 7 days prior to admission and during the confinement period. Subjects must have a negative test for cotinine prior to check-in on Day -1. Body mass index (calculated) within the range of 18 to 32 kg/m2 inclusive. Body weight ≥ 50 kg and ≤ 100 kg inclusive.  Medically healthy without clinically significant abnormalities, including:  Physical examination without any clinically significant findings, in the opinion of the Investigator. Systolic blood pressure (BP) in the range of 90 to 145 mm Hg (inclusive) and diastolic BP in the range of 50 to 90 mm Hg (inclusive) after at least 5 minutes in the supine position. Heart rate (HR) in the range of 40 to 100 beats/min (inclusive) after at least 5 minutes rest in a supine position. Normal body temperature 35.5 to 37.7°C (inclusive). Triplicate 12-lead electrocardiogram (ECG), taken after the volunteer has been supine for at least 5 minutes, with a QT interval corrected using the Fridericia method (QTcF) ≤ 450 msec for males and ≤ 470 msec for females and no clinically significant abnormalities, in the opinion of the Investigator. No clinically significant findings in serum chemistry, haematology, coagulation and urinalysis examinations, in the opinion of the Investigator.  Assessments may be repeated once, if abnormal values were recorded in the first instance, at the discretion of the Investigator.  Female volunteers must:  Be of non-child-bearing potential i.e., surgically sterilised (hysterectomy, bilateral salpingectomy, bilateral oophorectomy at least 6 weeks before the Screening visit) or postmenopausal (where postmenopausal is defined as no menses for 12 months without an alternative medical cause and a follicle-stimulating hormone level indicative of postmenopausal status per local laboratory definition), OR If of childbearing potential, must agree not to donate ova, not to attempt to become pregnant, and, if engaging in sexual intercourse with a male partner must agree to use an acceptable method of contraception for from signing the consent form until at least 15 weeks after the last dose of study drug. Male volunteers, must agree not to donate sperm and if engaging in sexual intercourse with a female partner who could become pregnant, must agree to use an acceptable form of contraception from signing the consent form until at least 15 weeks after the last dose of study drug. Have suitable venous access for blood sampling. Be willing and able to comply with all study assessments and adhere to the protocol schedule and restrictions.  Exclusion Criteria:  Healthy volunteers will be excluded from the study if there is evidence of any of the following at screening or after check-in on Day -1, prior to dose administration:  1. Prior exposure to STELARA® (Ustekinumab). Have a history of hypersensitivity or allergic reactions (either spontaneous or following drug administration) to any of the active or formulation ingredients of the study treatments components.  Have a history of or presence of disease determined by the PI to be clinically significant including:  gastrointestinal (including diverticulitis, stomach ulcers, inflammatory intestinal disease, gastrointestinal perforations/fistulae/intra-abdominal abscess). any other internal, non-gastrointestinal fistulae that is at an increased risk of bleeding. haematological (including pancytopenia, aplastic anaemia or blood dyscrasia). renal, hepatic, pulmonary, neurologic, psychiatric, metabolic (including known diabetes mellitus), or allergic disease excluding mild asymptomatic seasonal allergies. Have a history of prolonged immunosuppressant therapy, or photochemotherapy treatment. Presence or evidence of recent sunburn, scar tissue, tattoo (more than 25% of body area), open sore or branding that, in the opinion of the Investigator, would interfere with interpretation of skin adverse reactions.  Have a history of and/or current cardiac disease defined as one of the following:  History of congestive heart failure; angina pectoris requiring anti-anginal medication. Evidence of transmural infarction on ECG. History of sustained hypertension (systolic > 180 mmHg and/or diastolic > 100 mmHg) or hypertensive crisis or hypertension encephalopathy. Clinically significant valvular heart disease, or severe arterial thromboembolic events. Have a positive test result for hepatitis B surface antigen (HBsAg), hepatitis C virus, human immunodeficiency virus (HIV) or history of active, latent or inadequately treated tuberculosis (TB) infection. Positive serum pregnancy test for women of childbearing potential at the Screening visit or positive urine pregnancy test with confirmatory serum pregnancy test prior to dosing on Day 1. Females who are breastfeeding. Have a history of cancer including lymphoma, leukaemia and skin cancer (volunteers with a maximum of 1 surgically resected basal cell carcinoma or squamous cell carcinoma are permitted). Have an illness within 30 days prior to screening, or prior to dosing, that is classed as clinically significant by the Investigator. Prior exposure to any investigational monoclonal antibody within 12 months or 5 half-lives of the previous drug (if known), whichever is longer, prior to study drug administration. Have participated in another clinical study of an investigational drug (excluding monoclonal antibody) within 30 days or 5 half-lives of the investigational drug (whichever is longer) prior to the administration of the study drug, or are currently participating in another clinical study of an investigational drug, or intending to participate in another clinical study of an investigational drug before completion of all scheduled evaluations in this clinical study. Any clinically significant infection, in the opinion of the Investigator, ongoing at screening or admission to the clinical unit. Have had major surgery within 30 days prior to screening or will have an operation between screening and the end of study visit, or have any unhealed wound, including wound dehiscence and wound healing complications requiring medical intervention. Have received any vaccine(s) within 14 days prior to check in on Day -1, or is planning to receive any vaccine with 14 days following dose administration on Day 1. Have received a Bacillus Calmette-Guerin (BCG) vaccination within 1 year prior to dose administration, or is planning to receive a BCG vaccination within 1 year following dose administration. History of alcohol abuse (defined as more than 12 standard drinks per week or more than 4 standard drinks on > 3 days per week; where 1 standard drink is 10 g of pure alcohol and is equivalent to 285 mL beer [4.9% Alc./Vol], 100 mL wine [12% Alc./Vol], 30 mL spirit [40% Alc./Vol]) within 12 weeks prior to the screening visit. Positive drug or alcohol test results. In the event the urinary drug test is positive, the test may be repeated once (at the discretion of the PI) to confirm eligibility. Have donated > 100 mL blood within 4 weeks prior to the administration of the study drug. Abnormal or irregular bowel movements, in the opinion of the Investigator. Any history of non-traumatic haemorrhage (i.e. any haemorrhage requiring medical intervention) or any condition which may increase bleeding risk including clotting disorders, thrombocytopenia (platelet count < 150, 000 per μL) or an international normalised ratio higher than 1.5. Impaired liver function as determined by a serum alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST)> 1.5 x upper limit of normal (ULN) at screening or admission. Subjects with values between ULN and 1.5 x ULN may be included in the study if considered not clinically significant by the Investigator.  Use of any prescription or over-the-counter medication (including herbal products, diet aids, and hormone supplements) within 10 days or 5 half-lives of the medication (whichever is longer) prior to the first study drug administration, which, in the opinion of the Investigator, could affect the outcome of the study. The following exceptions apply:  Contraceptives for WOCBP are permitted. Paracetamol (up to a maximum of 4 doses of 500 mg per day, and no more than 3g per week) is permitted. Ibuprofen (up to a maximum of 4 doses of 200 mg per day) is permitted. Consumption of any foods containing poppy seeds within 48 hours prior to screening and admission to the clinical centre. Presence of proteinuria (other than trace amounts i.e., +, ++/+++). Personal history of venous thromboembolic events or idiopathic venous thromboembolic events in a first degree relative. Any person who is an employee of an Investigator or Sponsor, or an immediate relative of an Investigator. Any other condition or prior therapy that in the opinion of the Investigator would make the volunteer unsuitable for this study, including inability to cooperate fully with the requirements of the study protocol or likelihood of noncompliance with any study requirements.