Inclusion Criteria:  Adult males aged above 18 years old, no healthy volunteers included; Prostate cancer confirmed by pathological findings; High risk based on risk assessment, or laboratory tests suggestive of oligometastasis; Agreement to undergo laparoscopic radical prostatectomy + pelvic lymphadenectomy; ECOG score of 0 - 1 Agreement to undergo preoperative and postoperative endocrine therapy; Voluntary signing of an ICF for the clinical trial  Exclusion Criteria:  Any other tumor disease requiring treatment; Any organ metastasis confirmed by imaging, such as liver and brain metastases, or the possibility of paralysis due to spinal cord metastasis; A history of epilepsy or any condition that may lead to seizures; Severe liver or kidney dysfunction, severe cardiovascular or cerebrovascular diseases, and systemic immune system diseases.