Inclusion Criteria:  Being between the ages of 18-65, Being followed up with a diagnosis of knee-osteoarthritis by doctor  Exclusion Criteria:  Individuals under 18 and over 65 years of age, Individuals with acute or chronic inflammatory diseases, Individuals with chronic diseases, Individuals who consume alcohol, Smokers, Individuals who have not taken additional vitamin and mineral supplements in the last 6 months, Individualswho are not volunteer to participate in the study