Inclusion Criteria:  Pediatric patients requiring intubation in the pediatric intensive care unit Aged from 37 weeks corrected gestational age to 6 years Legal guardians providing written informed consent before the intervention or delayed consent in the event that emergency intubation is required  Exclusion Criteria:  Patients with known or suspected difficult/airways Congenital heart disease mandating FiO2 < 1.0, warranting inhalational induction, requiring ongoing CPR or advanced life support due to respiratory arrest Preterm age < 37 0/7 weeks Patients who cannot be intubated orally Respiratory insufficiency with an SpO2 saturation < 90 % after 2 min of preoxygenation with FiO2 = 1.0 Newborns requiring surfactant within the first 3 days of life Document stating intent to reject participation in research projects or refusal of intubation or refusal of resuscitation measures