Inclusion Criteria:  Men and women aged between 19 and 65 at screening visit. Patients who voluntarily sign the informed consent. Patients who can comply with the study procedures and visit schedule.  Exclusion Criteria:  Patients with infection, skin disorders, or scars at the glabellar region. Patients with facial palsy or the symptoms of blepharoptosis. Fertile women and men who have plans to conceive during pregnancy, breastfeeding and clinical trials or who do not agree to appropriate contraception. Subjects who are not eligible for this study based on investigator's judgement.