Inclusion Criteria:  Full term healthy infant (37-41 weeks amenorrhea) Birth weight >2750 g Aged between 2 and 8 weeks Presenting symptoms of infant colic as defined by Rome IV criteria by Zeevenhoven et al. 2017 Signed written informed consent of the parent/tutor  Exclusion Criteria:  Premature birth Using probiotics as a treatment, different from the one that could contain the formula at the time of study recruitment Acute or chronic illness as judged by the investigator which avoids the participation to the study . Parents unable to understand the requirements of study participation as judged by the investigator Malnutrition as judged by a body weight/height ratio <5 %