Inclusion Criteria:  patients suffering from muscular TemporoMandibular Dysfunctions (TMD) with clinical diagnosis: myofascial pain, limited opening of the mouth, articular noise. >= 18 years old with signed informed consent form  Exclusion Criteria:  articular TMD: arthritis or other inflammatory disease of temporomandibular joint, arthrosis, bone deformation, previous fracture of condylar area ; electromyographic hypoactivity, pure muscular diseases ; oro-mandibular dystonia ; botulinum toxin allergy, risk of bleeding recent or active infection intercurrent antibiotic treatment (drug interaction) ; vaccination during the 15 days preceding the injection.