Inclusion Criteria:  Man or woman age 18-75 years SARS-CoV2 positive as confirmed by SARS-CoV2 RT-PCR Test Diagnosed with pnumonia as confirmed by chect radiography and history of fever, coug with one of the following symptoms: RR > 30x per minute, SaO2 93%, FaO2/FiO2 300 mmHg Voluntarily joined the clinical trial and has signed the informed consent form  Exclusion Criteria:  Pregnant and lactating woman Patient who are diagnosed or have history of tumor and cancer Patient whose mother or sister are diagnosed with breast or ovarian cancer Level of SGPT/ALT is ≥ 5 times upper limit from normal value Level of eGFR is < 30 ml/min Reluctant to sign informed consent and unwilling to take the required tests Require invasive ventilation Shock Organ failure Currently involve in other clinical trial, or join another clinical trial in the last 3 months