Inclusion Criteria:  35 years of age or older, and gender not limited; Between 2 and 4 weeks onset of ischemic stroke; The first onset, or always not obvious legacy of stroke sequela (mRS acuities were before the onset of 1); Understand and voluntarily signed informed consent.  Exclusion Criteria:  Known severe liver or kidney dysfunction; Known allergies for ingredients in the investigational product; Known medical condition likely to limit survival to less than 3 months; Known dementia, mental impairment, or unsuitability for participation as judged by the investigators; Hemorrhage transformation after infarction, or bleeding tendency; Pregnancy or breastfeeding; Known lower extremity venous thrombosis; Having participated in others clinical trial within 1 month before randomization.