Inclusion Criteria:  Patient affiliated or benefiting from a social protection system Patient (or his/her trusted person) having given free and informed written consent to the investigating physician Non-neutropenic patient hospitalised in the Toulouse University Hospital intensive care unit. Patient with suspected invasive candidiasis for whom a blood culture for fungal infection diagnosis was taken and for whom an empirical treatment with echinocandin at an adapted dose was implemented.  Exclusion Criteria:  Patients under guardianship or trusteeship, persons under court protection Pregnant or breastfeeding patients.