Inclusion Criteria:  Meet the diagnostic criteria of acute exacerbation in chronic obstructive pulmonary disease or chronic bronchitis; Meet the diagnostic criteria of Phlegm-heat Syndrome (Tan-re Zheng) in TCM Age from 18 to 75 years old, regardless of gender; The score of each dimension of the sputum assement scale is ≥1; Those who have not participated in other drug clinical research in the past one month; Sign the informed consent letter.  Exclusion Criteria:  Patients with pulmonary tuberculosis, bronchial cancer or other lung diseases. Loose stools due to Spleen deficiency and stomachache caused by cold. Diabetes or severe cardiovascular, liver (ALT>1.5×ULN), kidney (Cr>1.5×ULN) and other primary diseases. Pregnant and lactating women. Patients with acute and chronic respiratory failure. Those who cannot give full informed consent due to mental disorders. People with disabilities recognized by law. People with allergies, or allergic to the ingredients of the drug used in this test. Those who have used drugs with expectorant effects within the day. Patients who are participating in clinical trials of other drugs. -