Inclusion Criteria:  18-65 years old, newly diagnosed as Ph+ALL. Sign the informed consent. Accept consolidation chemotherapy. Accept follow-up.  Exclusion Criteria:  Liver and kidney function impairment: serum transaminase > 2 times of the upper limit of normal value, total bilirubin > 1.5 times of the upper limit of normal value, serum inosine > the upper limit of normal value (97 umol/L). Active hepatitis B, hepatitis C or tuberculosis infection. Can not tolerate the adverse effects of dasatinib. Pregnancy. Diagnosis of mental disorders. Do not accept follow-up.