Inclusion Criteria:  Subject must have voluntarily signed the informed consent form. Male or female patient aged ≥18 Years old. Replacing a missing tooth by use of implant supported restoration in implantation sites that do not require extensive augmentation procedure. Good primary implant stability at implant placement (35N and more). Compliance with study schedules and arrival at study visits.  Exclusion Criteria:  Pregnant or lactating women. Imbalance diabetes. Head and neck rediation therapy. Active Periodontal disease and caries. Patient in need of tooth extraction and immediat implantation.