Inclusion Criteria:  Age ≧ 18 years, < 65 years; Patients who planned coronary angiography (hypertension 、renal failure、atherosclerosis）; Patients with normal renal function or CKD stage 1-3; Patients themselves or authorized families to sign informed consent voluntarily.  Exclusion Criteria:  Patients who were allergic to iodine contrast agent or had allergic history or allergic constitution to iron and dextran; Patients who can ' t accept magnetic resonance examination because of psychological ( such as autism syndrome ) or physical reasons ( such as metal retention in the body ); Malignancies or other comorbid conditions with life expectancy less than 1 year; Pregnant or lactating woman; Hearing impaired persons; Cardiac function grade III-IV; History of coronary stenting or coronary artery bypass grafting; Patients who were taking other iron agents orally or intravenously; Patients with hemosiderin deposition or hemochromatosis; Patients with acute coronary syndromes; Any other patients that researcher deems it's unsuitable to be admitted.