Inclusion Criteria:  Fifty one female patients have unilateral with mild to moderate CTS in dominant hand diagnosed and reffered by physician.  Age will be ranged from 30-45years (Atya et al.,2020) Patients with mild to moderate CTS will particiepate into the current study according to the classification of AAEM  Exclusion Criteria:  Patients with diabetes mellities ( type I or type II), Patients with Hypertension Patients with hypothyroidism Patients with rheumatological disease Patients with renal disease