Inclusion Criteria:  Referred or Admitted to an emergency department Clinical suspicion of PE raised by physician requiring further diagnostic imaging  Exclusion Criteria:  Refusal of informed consent Pregnancy Permanent mental disability Age <18 years Diagnosis of PE within the last 6 months Hemodynamic instability (systolic blood pressure <90 mmHg for at least two consecutive measurements) Ultrasound of heart, lungs or deep veins performed prior to enrollment