Inclusion Criteria:  Women 50 years or older Low to intermediate grade DCIS or invasive ductal carcinoma Tumor size < 2 cm invasive ductal carcinoma and < 2.5 cm DCIS Well defined lumpectomy cavity on CT Clear surgical ink margins > 2mm for invasive cancer and > 3 mm for DCIS Node negative Unifocal lesion ER and/or PR positive HER-2 negative BRCA negative Lumpectomy cavity must be < 30% of whole breast volume  Exclusion Criteria:  Lobular histology Angiolymphatic invasion Multiple foci of disease Lymphovascular invasion Active lupus or sarcoid Distant metastases Non-epithelial malignancies Synchronous contralateral breast cancer Grade 2 or higher oncoplastic surgery Ipsilateral pacemaker Ipsilateral breast implant Neoadjuvant chemotherapy Prior ipsilateral breast cancer or thoracic radiation Poor breast integrity Paget's Disease of the nipple Pregnant patients Severe cardiac, pulmonary, or liver diseases