Inclusion Criteria:  more than 18 years of age Diagnosed with pancreatic cancer and has consented to undergo the NanoKnife procedure per the treating physician Willing and able to comply with the protocol requirements Able to comprehend and sign the Informed Consent Form in English or Spanish  Exclusion Criteria:  Patients who meet any of the following criteria will be excluded from the study:  Do not meet the Study Inclusion Criteria laid out above