Inclusion Criteria:  Adult participants are age 65-80 who may have underlying chronic diseases but no advanced kidney disease or diabetes requiring insulin. Subjects with a diagnosis of pre-frailty according to Fried's modified criteria. Subjects with a minimum BMI of 20 kg/m2 Subjects with a bio-impedance phase angle >5°.  Exclusion Criteria:  Known allergy to components of the kit. A previous significant reaction to vaccination or if they refuse to receive influenza vaccination. Known immunosuppressive disorders or medications; Subjects who report respiratory illness within the two-week period prior to vaccination;  7. Subjects with a BMI <20 8. Subjects with a bio-impedance phase angle <5°.