Inclusion Criteria:  diagnosis of TMD according to the Diagnostic Criteria for TMD Research Diagnostic Criteria (DC/TMD）which are manifested as joint pain during mouth opening and chewing, mouth opening limitation (<40mm), joint clanging, masticatory creatine distension and weakness, which affects normal eating. Aged 18-65; Unilaterally; No any other treatment on TMD in the last 3 months;  Exclusion Criteria:  there are tumors, joint degeneration and other serious lesions ; Patients with a history of TMJ trauma or surgery,joint anatomical variation; women pregnant and suckling period; serious systemic diseases of bone and joint, such as rheumatoid arthritis