Inclusion Criteria:  Men scheduled for radical prostatectomy  Age over 18 years GG 3-5, cT2-cT3, Nx, M0 prostate cancer no contraindication to PSMA - or FAPI-PET willing to undergo study related procedures (imaging and laboratory tests) Men scheduled for novel antiandrogen Age over 18 years GG2-5, cT2-4, N0-1, M1 hormone sensitive or castration resistant prostate cancer  Exclusion Criteria:  Not willing or capable to undergo study related procedures