Inclusion Criteria:  Diagnosis of Major unipolar depression for at least 4 weeks meeting the criteria of the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) and the Mini International Neuropsychiatric Interview (M.I.N.I) Age between 18 to 65 Minimum score of 17 on the GRID-Hamilton Depression Rating Scale (GRID-HAMD)  Exclusion Criteria:  Bipolar disorder, Psychosis Active substance use disorder (in the last 3 months) Personality disorder Neurocognitive disorder High risk of suicide Major comorbid medical or neurological condition Pregnancy  Medical contraindications to tDCS:  Ferromagnetic material in the skull Defect in the bone substance of the skull Dermatological condition (e.g. eczema, psoriasis, urticaria, dermatitis, acne, hyperhidrosis, folliculitis, rosacea, keratosis, herpes, infectious or neoplastic phenomenon, etc.) Skin lesion on the skull (ex: cuts, abrasions, rash, tattoos on the skull, piercings on the head, etc.)