Inclusion Criteria:  Age > 18 years old Acute Kidney Injury grade 3 (KDIGO) Indication for renal replacement therapy for the clinician in charge  Exclusion Criteria:  Emergency indication to renal replacement therapy (pH<7.15, Kaliemia > 6mmol/L, refractory pulmonary oedema) Poor echogenicity with speckle tracking analysis failure Chronic hemodialysis Extra corporeal membrane oxygenation, left ventricular assist device.