Inclusion Criteria:  Benign PA of major and minor salivary glands (PA group), CXPA of major and minor salivary glands (CXPA group). Border of excision biopsy of mucocele in the lip mucosa of healthy individuals used as normal controls (Control group). Surgical excision of tumors with no preoperative chemotherapy or radiotherapy. For parotid tumours partial or total parotidectomy, Surgery was performed with or without facial nerve preservation and the later was carried out commonly when the nerve was involved by tumour. For tumours in the other glands, complete surgical excision with the involved gland and the suspicious adjacent structures was performed.  Exclusion Criteria:  All epithelial origin salivary gland tumours other than PA and CXPA. All mesenchymal origin salivary gland tumours. All inflammatory and cystic lesions of salivary glands. Metastasis in salivary glands. Patients received preoperative chemotherapy or radiotherapy.