Inclusion Criteria:  Adult patient age >18 years. Patients with chronic shoulder pain more than 6 months not responding to medical treatment or physical therapy. Frozen shoulder. Rotator cuff disorders (partial tear).  Exclusion Criteria:  Shoulder joint instability or traumatic shoulder pain. Patients with local infection at the shoulder, systemic infection, or inflammatory disease (e.g., rheumatoid arthritis and hepatitis) Patients with a history of diabetes mellitus and malignancy (either hematological or non-hematological). Pregnancy. Patients on anticoagulant therapy. Injection of shoulder with corticosteroids in the preceding 6 months.