Inclusion Criteria:  Adults (greater than or equal to [>=]18 years old) at the time of signing the informed consent. HIV-1 infected and have been on oral VOCABRIA + EDURANT for approximately 1 month (at least 28 days) or already taking CABENUVA prior to Baseline/Month 1 and the last dose was within a 1 month plus minus (+-) 7-day window. Capable of giving signed informed consent. Agreement to receive CABENUVA IM injections at participating infusion center.  Exclusion Criteria:  Participants are excluded from the study as dictated in the Prescribing Information (CABENUVA United States Prescribing information [USPI], 2021) in consultation with the HIV care provider.