Inclusion Criteria:  BMI ≥ 30 kg/m2 HbA1C < 48 mmol/mol Written informed consent Liver steatosis > 10% on MR-spectroscopy Premenopausal women will have a negative pregnancy test drawn within 48 hours before the study.  Exclusion Criteria:  Other chronic liver diseases (HBV, HCV, AIH, PBC, PSC, alcoholic steatosis) Known systemic disease exempting hypertension and dyslipidemia. Former or active malignant disease Alcohol consumption >2 drinks/day for men, 1 drink/day for women, evaluated by AUDIT-C Pregnancy Any medications including non-prescription medications exempting, birth control medications, antihypertensives and statins. Participants taking statins can participate on the condition of a 2 week pause before the experimental days. Estimated glomerular filtration rate <90 ml/min Currently smoking Blood donation within the last 3 months Weight above 130 kg Participated in trials using radioactive isotopes within the last 6 months