Inclusion Criteria:  Clinically diagnosed as large or giant hepatocellular carcinoma of the right lobe of the liver; Child-Pugh liver function grade A, ECOG PS 0-1 If the tumor is resected with R0, the remaining liver volume is insufficient ICG-15R < 30% No serious organic diseases of heart, lung, brain and other organs; No history of other malignant tumors; The patient's survival time is expected to be more than 3 months.  Exclusion Criteria:  Pregnant and lactating women History of organ transplant Tumor thrombus with portal vein trunk or left branch involved; distant metastasis; Patients with obvious liver cirrhosis (Plt < 100 × 10 ^ 9 / L at admission or gastroscopy suggested esophageal and gastric varices); Active bleeding caused by various causes; Suffering from severe acute or chronic diseases or infectious diseases; History of hepatectomy or TACE treatment.