Inclusion Criteria:  Patients diagnosed as suffering from Crohn's disease (CD), Ulcerative colitis (UC) or Pouchitis for at least 2 months who are in clinical and biologic remission according to Steroid free clinical remission for greater or equal to 3 months according to the following activity index  Harvey Bradshaw index (HBI)<5 for CD patients Simple Clinical Colitis activity index (SCCAI)≤2 for UC patients Pouch disease activity index ≤6 / mPDAI ≤4 for Pouch patients  Also, patients will be included if they fullfull the following:  Age 18-80 years Clinically stable patients, on constant medicinal regimen (mesalamine at least 4 weeks, or immunomodulators at least 12 weeks or biologics at least 12 weeks therapy, medical cannabis at least 2 weeks before inclusion to the study)  Exclusion Criteria:  • Inability to sign an informed consent and complete the study protocol  Steroid therapy during the past 3 months Antibiotic therapy during the past 2 weeks Unstable or uncontrolled medical disorder, and sever systemic disease (other than IBD) Participating in another clinical interventional trial Stoma