Inclusion Criteria:  Minimum of 5 actinic lentigos and 3 actinic keratoses of grade 1 or 2 on each hemi-face of the face and/or hemi-cranium (in men with baldness) Phototype I to III Patients with free, informed, written consent to participate in the study. Women unable to conceive or women of childbearing potential with a negative urine pregnancy test and using contraception  Exclusion Criteria:  Subjects with less than 5 actinic lentigos or less than 3 actinic keratoses of grade 1 or 2 on each hemiface of the face and/or skull (for men with baldness) Phototype IV to VI Immunocompromised subject Subjects with a history of skin carcinoma in the treated areas Subjects using another active treatment for actinic keratoses or lentigos (or having used one in the past 3 months) Subjects unable to understand the information (due to language or psychiatric reasons) Subjects without social insurance Pregnant women Breastfeeding women Women of childbearing age without contraception Subjects under legal protection measures Subjects unable to express their consent Subjects under legal protection