Inclusion Criteria:  Severe primary mitral valve regurgitation according to current guidelines with indication for mitral valve repair With or without concomitant procedures such as: coronary artery bypass grafting (CABG), other valve repair/replacement, pacemaker implantation, exclusion of left appendage and MAZE (or PVI) procedure, aortic procedures Euroscore II < 8 Left ventricle ejection fraction > 35% Life expectancy above 1 year after the intervention based on operator assessment Willing to sign informed consent Willing to undergo all medical follow-ups necessary for the clinical investigations until study termination (echocardiography, blood tests, physical investigation)  Exclusion Criteria:  Age <18 years Active endocarditis or myocarditis Previous cardiac surgery Heavily calcified mitral valve annulus Severe mitral stenosis Female pregnant patients Emergency procedures Patient not able to read or understand informed consent Patient not willing to sign informed consent