Inclusion Criteria:  Adult (≥18 years old) at the time of consent Positive COVID-19 PCR test result  Exclusion Criteria:  Expected death or withdrawal of life-sustaining treatments within 3 days Hemoglobin ≤7.0 at the time of consent Unable to provide consent and no legally authorized representative (LAR) identified or reached by phone Pregnant Incarcerated Physician declines patient enrollment (attending physician or study physician) Patient or LAR do not consent to participate in the study