Inclusion Criteria:  RB-approved informed consent, age 18 years or older, male or female, anyone considering COVID-19 vaccination or anyone that has received COVID-19 vaccination.  Subjects can enroll at anytime after vaccination even though they may not have enrolled before vaccination.  Sampling Frequency and timing: Up to 8 total samples in 12 months -  Exclusion Criteria:  Exclusion: Failure to provide informed consent  -