Inclusion Criteria:  Age over 18 years; Acute circulatory failure from any cause defined as low blood pressure (systolic blood pressure less than 90mmHg and/or mean arterial pressure less than 65mmHg) and/or marbling and mechanical ventilation; Affiliation with a social security scheme or entitled to it; Information and non-objection of the patient to participate in the research.  Exclusion Criteria:  -