Inclusion Criteria:  Age: 18-80; Spontaneous cerebral hemorrhage; Deep supratentorial intracerebral hemorrhage (basal ganglia) with hematoma volume 5-40ml, or supratentorial lobar hemorrhages with hematoma volume 5-30ml; NIHSS: 6-20; Time from onset to DELP: 6-48 hours; Premorbid mRS 0 or 1; Signed informed consent;  Exclusion Criteria:  Secondary cerebral hemorrhage (secondary to trauma, tumor, vascular malformation, hemorrhage transformation of ischemic stroke, etc.); Comatose patients on admission (GCS score 3-8 on the Glasgow Coma Scale); Patients with intracerebral hemorrhage ruptured into the ventricle, which should be treated by surgery; Planed surgery; Severe hepatic or renal dysfunction, increase in ALT or AST (more than 2 times of upper limit of normal value), increase in serum creatinine (more than 1.5 times of upper limit of normal value) or requiring dialysis; Severe hypertension (systolic blood pressure over 200mmHg or diastolic blood pressure over 110 mmHg), or hypotension (systolic blood pressure below 90mmHg or diastolic blood pressure below 60 mmHg); Previous allergy to heparin or calcium; Life expectancy is less than 6 months due to comorbidity Infected at the venipuncture site hypoproteinemia; Unsuitable for this clinical studies assessed by researcher.