Inclusion Criteria:  Premature infants 24-36 weeks gestational age Full-term infants 37-42 weeks gestational age Less than 48 hours of age at enrollment Admitted to the neonatal intensive care unit of Indira Gandhi Institute for Child Health, Cloudnine Hospital at Old Airport Road and Cloudnine Hospital at Jayangar, Bangalore Expected to be in the neonatal intensive care unit for at least 4 days after enrollment Able to tolerate study procedures as described Parent/guardian willing to provide written informed consent  Exclusion Criteria:  Medically unstable Parent/guardian unable to provide written informed consent Presence of inherited cutaneous condition e.g., scalded skin syndrome, epidermolysis bullosa Presence of major congenital anomalies Infants undergoing surgery