Inclusion Criteria:  Age >18 years Both genders Diagnosis of non-M3 AML by the WHO 2016 diagnostic criteria Patients eligible and not eligible for transplant Patients eligible and not eligible for intensive treatment AML secondary to treatment or associated to myelodisplasia Leukocytes ≥50x106/L Not being able to receive chemotherapy in the next two days  Exclusion Criteria:  AML with PMP/RAR-alfa translocation t(15;17) Poor functional status (ECOG>2) Active infection Pregnancy