Inclusion Criteria:  Age ≥18 years Undergoing a PCI Use of a parenteral antiplatelet agent (GPIs or cangrelor)during the invasive procedure (PCI)  Exclusion Criteria:  Blood dyscrasia, bleeding diathesis or active bleeding at the time of the index procedure. Chronic oral anticoagulation. Recent history of stroke, TIA (Transient Ischemic Attack)or intracranial bleeding (<3 months prior to inclusion). Severe anemia (Hb<9g/dl) or platelet count <100x106/ml at the time of the index procedure. Any active neoplasm.