Inclusion Criteria:  Ascites and/or variceal hemorrhage (VH) as the first decompensated events; Initiating antiviral therapy within 3 months of the first decompensated events; Clinical parameters were available at the first decompensated events, including PLT, ALT, ALB, TB, PT/INR, Cr, HBV DNA, BUS,  Clinical outcomes were classified:  Without further decompensation: medical records at year-1, year 2 to 4, and year-5 were available. With ≥ 2 episodes of decompensation: medical records for decompensation were available.  Exclusion Criteria:  Hepatocellular carcinoma prior to /within 6 months of first decompensated events; Liver transplantation /death within 6 months of first decompensated events; complicated with other chronic liver diseases, including HCV, DILI, AIH, NAFLD, ALD. Any complication of severe heart, lung, kidney, brain, blood diseases or other severe systematic diseases; Pregnant women.