Inclusion Criteria:  HCV RNA ≥ 15 IU/Ml at Screening HCV genotype 3a ,3b and 6 Hepatitis C without decompensated cirrhosis of the liver  Exclusion Criteria:  Patients failed to previous NS5A-containing DAAs therapy Decompensated cirrhosis HCC Infection with hepatitis B virus (HBV) or human immunodeficiency virus (HIV).