Inclusion Criteria:  18 ≤ age ≤ 70 years, male or female; Voluntarily participate in the study and sign the informed consent form; Diagnosis of ARDS for no more than 48 hours (starting at the time of diagnosis recorded in the medical record)；  The following 2012 Berlin definition criteria for mild to moderate ARDS were met:  From known clinical impairment and new or worsening of respiratory symptoms to fulfillment of diagnostic criteria is less than 7 days(inclusive). Chest imaging suggests bilateral infiltrates. The effusion, lobar/atelectasis, or nodules cannot completely explain the phenomenon. Respiratory failure cannot be completely explained by heart failure or fluid overload; When PEEP or CPAP ≥5 cm H2O, 100 mmHg≤PaO2/FiO2≤300 mmHg; Male subjects agree to use an effective contraceptive method from the start of the study until 7 days after the end of treatment; Female subjects of childbearing age agree to use an effective contraceptive method from the start of the study until 3 months after the end of treatment.  Exclusion Criteria:  Positive serum pregnancy test before dosing for women of childbearing potential, pregnant women, or lactating women; Terminal phase of chronic disease with an expected survival of no more than 6 months;  Combined with one of the following chronic organ damage or immunosuppressive diseases:  Heart: New York Heart Association functional class IV; Lung: severe lung disease, including pulmonary hypertension, oxygen therapy or ventilator dependence for more than one month cumulatively within the first six months of screening, end-stage lung disease, or severe exercise limitation caused by chest wall malformations; Kidney: ongoing long-term dialysis treatment; Liver: biopsy confirmed cirrhosis and portal hypertension, or previous upper gastrointestinal bleeding caused by portal hypertension; Liver failure, hepatic encephalopathy, or hepatic coma; Immunosuppression: with lymphoma, leukemia or acquired immunodeficiency; Received anti-tumor chemotherapy in the last 3 months, or ongoing immunosuppressive therapy due to organ transplantation, immune diseases, etc.; Has undergone allogeneic bone marrow transplantation or hematopoietic stem cell transplantation; Steroid hormone therapy in the last 3 months (equivalent to > 0.5 mg/kg/day prednisone continued 1 month);  History of one of the following within 4 weeks prior to screening:  Acute pulmonary embolism; Cardiac arrest; Acute myocardial infarction; eGFR < 60 mL/min/BSA (calculated using CG formula); ALT > 5 x ULN, or total bilirubin > 2 x ULN; Severe anemia (hemoglobin < 7.0 g/dL); Absolute neutrophil count < 1500/μL; Platelet count < 50,000/μL; aPTT > 1.5 × ULN; Active bleeding that cannot be effectively controlled; The subject required therapeutic doses of heparin or was taking anticoagulants; ARDS caused by direct lung injury due to physical or chemical causes; Severe or greater burns: the overall surface area of burns exceeds 30% or the III degree burn area exceeds 10%; or the total area is less than 30%, but the general condition is severe or has shock, combined injury, respiratory tract burn; Allergic to the active ingredients or excipients of the study drug; Subjects have participated in other clinical studies (other than those who have not received intervention) or are participating in other experimental treatments within 1 month prior to screening; In the opinion of the investigator, the subject could not benefit from the study or was not suitable for participation in the study.