Inclusion Criteria:  Primary urinary bladder tumor Secondary urinary bladder tumor (recurrence) Bipolar or monopolar resection Creat <2.2mg/dl 35% <Hct <52% White bloode cells count WBC ≥3000 / μL 75000 <PLT <500000 / μL Urine culture: negative / sterile Alkaline phosphatase, total bilirubin, SGOT, SGPT: values as high as 2 times above the upper normal limit Good clinical condition (according to Eastern Cooperative Oncology Group PS ≤ 1) CT Urography without findings suggesting an upper urinary tract tumor in the last 3 months before the transurethral resection of the bladder tumor  Exclusion Criteria:  More than 2 low grade / high differentiation (low grade / LG) histologically confirmed bladder tumors in the last 18 months before the transurethral resection of the bladder tumor High grade / low differentiation (HG) histologically confirmed bladder tumor in the last 9 months before the transurethral resection of the bladder tumor Those who undergo a transurethral resection of a bladder tumor according to the Guidelines of the European Association of Urology for non-muscle-invasive bladder cancer: incomplete resection of tumor, absence of muscle fibers in the sample with the exception of: Ta / LG-G1, primary Cis and finally, pT1 tumors Intravesical instillation of chemotherapeutic agent or BCG in the last 6 months before the transurethral resection of the bladder tumor History of non-urothelial bladder cancer Stage of disease pT2 (muscle-invasive bladder cancer) Presence of a tumor in the urethra Upper urinary tract malignancy (present or anamnestically) History of pelvic radiotherapy Histrory of another malignancy in the last 5 years before the transurethral resection of the bladder tumor