Inclusion Criteria:  Patients aged between 18 and 65 years Undergoing general anesthesia for nose and ear surgery Physical status according to the American Society of Anesthesiologists I and II  Exclusion Criteria:  Refusal to participate in the study Presence of kidney, liver or neuromuscular disease Contraindication to the use of any of the drugs used in the study Body mass index (BMI) ≥ 30