Inclusion Criteria:  Aged 50-80 years； Office blood pressure ≥130/80mmHg and<160/100mmHg; and 24-h ambulatory systolic/diastolic blood pressure ≥125/75mmHg; Never taking antihypertensive drugs or have stopped taking antihypertensive drugs for more than one month; Do not receive any antihypertensive drugs during the research; Informed consent obtained from the subjects or their legally authorized representative.  Exclusion Criteria:  Secondary hypertension; Patients who are taking antihypertensive drugs regularly; Patients with contraindication for remote ischemic conditioning, such as vascular injury, soft tissue injury, orthopedic injury, or arm infection; Patients with bleeding disorder; Patients with atrial fibrillation or other severe arrhythmias； Patients with prior myocardial infarction or stroke； Patients with serious or unstable medical condition, such as severe liver or kidney dysfunction, heart failure, respiratory failure, malignant tumors, or autoimmune diseases; Participation in another device or drug trial simultaneously; Patients who are not suitable for this trial considered by researchers for other reasons.