Inclusion Criteria:  Age ≥18 years. Able to understand the objectives of the study and to provide informed consent. Body mass index between 18.5 and 24.9 kg / m2 Active sportsman/woman (defined as previous experience with the planned tests and performing vigorous-intensity aerobic activity at least three times per week).  Exclusion Criteria:  History of chronic kidney disease, hypertension, uncontrolled diabetes (defined as fasting glucose levels ≥200 mg/dl or HbA1c ≥9%), peripheral vascular disease, heart disease, neurological disease or thyroid disease. Use of NSAIDs in the 72h prior to the test. Consumption of statins or anabolic steroids. Some kind of major physical injury in the four months prior to the tests.