Inclusion Criteria:  Able and willing to provide a written informed consent Subjects requiring local anesthesia assisted sedation Male or female Meet the weight standard Conform to the ASA Physical Status Classification  Exclusion Criteria:  Previous respiratory or pulmonary diseases Subjects who had received general anesthesia Subjects with a history of myocardial infarction or unstable angina pectoris Subjects with atrioventricular block or cardiac insufficiency Subjects with a history of ischemic stroke or transient ischemic attack Subjects with poor blood pressure control after medication Subjects with abnormal clotting function Subjects with a history of mental illness and a history of cognitive impairment epilepsy Subjects with a history or possibility of a difficult airway Subject with a history of substance abuse and drug abuse Abnormal values in the laboratory Allergic to a drug ingredient or component Pregnant or nursing women No birth control during the specified period of time Participated in clinical trials of other drugs (received experimental drugs) The inestigators determined that other conditions were inappropriate for participation in this clinical trial