Inclusion Criteria:  Age > 21 years BMI ≤ 35 ASA ≤ 3 Willing and able to provide a written informed consent Willing and able to comply with the study protocol requirements including follow-up examinations at 14 days and 30 days post-operatively, and post-market long term follow-up on an annual basis through 5 years  Lobectomy Inclusion Criteria:  - Clinical stage I or II primary lung cancer or other suspected lung malignancy; or benign lung disease requiring resection; primary tumor ≤ 5cm diameter  Thymectomy Inclusion Criteria:  - Masaoka clinical stage I or II thymoma; or thymectomy for myasthenia gravis; thymic mass ≤ 5 cm diameter  Exclusion Criteria:  Clinical or radiological evidence of mediastinal or systemic metastatic disease Life expectancy < 6 months Subject with a known bleeding or clotting disorder Subjects actively receiving therapeutic-dose anticoagulation or anti-platelet medications at the time of operation Uncontrolled systemic illness 6 months prior to planned surgical procedure including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements Previous chemotherapy, immunotherapy and/or radiation therapy for treatment of the cancer to be resected Subject has a contraindication for general anesthesia or surgery Subjects under active immunomodulatory or immunosuppressive regimen (e.g. transplant patient, high-dose steroid requirement) within 30 days prior to the planned surgical procedure. For myasthenia patients, if steroids are weaned down to prednisone ≤ 5 mg/day prior to day of surgery, the patient may be enrolled Previous sternotomy Subject belongs to vulnerable population Subject is pregnant or suspected to be pregnant or breastfeeding  Lobectomy Exclusion Criteria:  Tumor involving carina or any airway requiring sleeve resection, bronchoplasty Tumor requiring resection of local structures (e.g. chest wall) or extended resection such as bilobectomy History of pulmonary hypertension Previous ipsilateral thoracic surgery or radiotherapy  Thymectomy Exclusion Criteria:  Uncontrolled myasthenia gravis symptoms at the time of scheduled surgery Tumor requiring resection of local structures (except pericardium) Confirmed thymic carcinoma  Intraoperative Exclusion Criteria:  - Anatomy determined intra-operatively to be unsuitable for minimally invasive surgery