Inclusion Criteria:  Positive SARS-CoV-2 RT-PCR result, Adult hospitalized patient, The patient has the physical and psychological ability to follow the instructions in the study.  Exclusion Criteria:  Patients intubated and supported by a mechanical respirator, Severe acute or chronic medical or psychiatric condition, History of significant adverse effects following use of oral hygiene products such as toothpaste and mouth rinses, Active uncontrolled thyroid disease, Developmental/cognitive disability, Pregnancy, Undergoing radioactive iodine therapy.