Inclusion Criteria:  Over 19 ages healthy men Over 50.0kg, 18.0kg/m2 ≤ BMI ≤ 30.0kg/m2 Men who don't have congenital disease and other cronic disease need to be cared. etc.  Exclusion Criteria:  Men who have congenital liver disease (AST, ALT, CK ≥ 2X ULN) Men who have drunken or eatten something including caffeine within 24 hours before. etc.