Inclusion Criteria:  Patients aged 18 years or older, for whom the trusted person designated by the patient or, failing that, a relative has read and signed the consent form for participation in the study Patient hospitalised in intensive care, under sedation and controlled mechanical ventilation Equipped with a central venous line in the superior vena cava territory and an arterial catheter. Whose state of health justifies vascular filling  Exclusion Criteria:  Patient under legal protection, guardianship or curatorship Pregnant or breastfeeding woman Patient not affiliated to the French social security system Contraindication to the realization of an alveolar recruitment maneuver