Inclusion Criteria:  Women >25 years of age; Women undergoing colposcopy due to abnormal cervical screening or follow-up for a history of dysplasia; Women of childbearing potential must have a negative urine or blood pregnancy test; Ability to understand and willingness to provide informed consent by signing specific Informed Consent Document.  Exclusion Criteria:  Women under 25 years of age; Women who have undergone hysterectomy with removal of the cervix; Women with known allergy to proflavine or acriflavine; Women who are pregnant or nursing at the time of enrollment; Incapacitated women or in vulnerable situations or who are not willing to give consent;