Inclusion Criteria:  For Test Group 1 and 2 - subjects with renal impairment  Age 19~65 BMI 18.0~30.0 kg/m^2 (Body mass index) 30 ≤ eGFR < 60 mL/min/1.73m^2 (estimated glomerular filtration rate) voluntarily given written informed consent  For Control Group - healthy subjects  Age ≥ 19 BMI 18.0~30.0 kg/m^2 eGFR ≥ 90 mL/min/1.73m^2 voluntarily given written informed consent  Exclusion Criteria:  For Test Group 1 and 2 - subjects with renal impairment  Medical history  Subjects with lactic acidosis or marked hepatotoxicity Not controlled diabetes, hypertension, dyslipidemia requiring dialysis  Clinical examination  AST, ALT > 2, Bilirubin total, γ-GTP > 1.5, CK > 2 times the upper limit of normal ranges (Aspartate transaminase, Alanine transaminase, gamma-Glutamyl transpeptidase, Creatine phosphokinase) Positive serologic results Drug hypersensitivity and drug abuse  For Control Group - healthy subjects  Medical history  History of chronic liver disease, hepatic encephalopathy, ascites, or upper gastrointestinal bleeding Subjects with lactic acidosis or marked hepatotoxicity  Clinical examination  AST, ALT > 2, Bilirubin total, γ-GTP > 1.5, CK > 2 times the upper limit of normal ranges Positive serologic results Drug hypersensitivity and drug abuse