Inclusion Criteria:  Randomised to the INTENT trial at a participating sub-study site  Exclusion Criteria:  Patients will be excluded from the sub-study if they have any of the following:  A pacemaker or electronic implantable device Missing limb(s) Unable to get adequate separation in the limbs (e.g. severe obesity) Inaccessible site(s) for electrode placement (e.g. major burns, trauma) Broken skin at the site(s) of electrode placement The treating clinician does not believe the study to be in the best interest of the patient Person responsible/Medical treatment decision maker is of non-English speaking background (therefore cannot provide informed consent) Note Before: If the Person responsible/medical treatment decision maker is of English speaking background but the patient is not (and the Person responsible/Medical treatment decision maker speaks the same language as the patient) you may continue assessing the patient for eligibility to INTENT-Muscle as the Person Responsible/Medical treatment decision maker can translate the Patient Information and Consent Form (PICF) and consent discussion with the patient in order to obtain continuing consent)