Inclusion Criteria:  Subject has documented ATTR-CM. For the reproductive criteria for male and female participants, please refer to relevant protocol sections.  Exclusion Criteria:  Other acute or chronic medical or psychiatric condition including recent or active suicidal ideation or behavior or laboratory abnormality, in the judgment of the investigator, would make the participant inappropriate for entry into this study. Participants who have prior liver and/or heart transplant. Participants with primary (light chain) or secondary amyloidosis. Previous administration with an investigational drug within 30 days or 5 half lives preceding the first dose of study intervention used in this study (whichever is longer).