Inclusion Criteria:  Understand the present studyAgree and sign informed consert Age is between 18 and 70 Men or women ≧18 years and <70 years of age at screening Treated with maintenance blood purification 2 or 3 times blood purification treatments (including hemodialysis, hemofiltration, hemoperfusion) every week2 or 3 times a week, Blood purification treatment more than 3 month before randomization Blood purification by uUsing AV fistula or artificial vascular access DiagnosisWith chronic heart failure (NYHC II-IV), and NT-proBNP>11500 or BNP>500 ARNI or RAS inhibitor or Aldosterone inhibitors or beta receptor blocker treatment for at least 4 weeks with a stable dose.  Exclusion Criteria:  Blood purification less than 3 month With fluid overload and URR<50% Have severe hypoglycemia (more than 2 events with 4 weeks prior to sign concert information) Have severe hypotension (blood pressure <90/60mmHg more than 3 times with 4 weeks prior to sign concert information) Have acute pulmonary edema Have ketoacidosis Have active pyelnephritis and symptomatic lower urinary infection Subject is pregnant , is breast feeding Subject has known SGLT2 inhibitor allergy or intolerance adverse reactions Subject is currentluy enrolled in or has not yet completed at least 30days since ending other investigational device or drug trials Investigator believe subject is not suitable for this study