Inclusion Criteria:  Persons with confirmed arterial hypertension; The age of patients is from 18 to 55 years old inclusive; Persons of Kazakh nationality, whose paternal and maternal grandparents identify themselves as Kazakhs; Persons who are able and willing to provide written informed consent; Persons capable and willing to comply with the research protocol;  Exclusion Criteria:  Persons under 18 and over 55; Persons who, in the opinion of the researcher, are mentally or legally incapacitated, which prevents obtaining informed consent; Pregnant or lactating women; Tuberculosis of any localization in the active phase and in history; Severe and decompensated diseases of the liver and kidneys, cardiovascular system; Severe and decompensated course of endocrine diseases; Autoimmune diseases; Systemic diseases; Cancer.