Inclusion Criteria:  A. Patients with familial hypercholesterolemia (FH) and with hyperTG :  Age > 18 years Molecular or clinical diagnosis of FH Primary prevention (no coronary artery disease, cerebrovascular disease or lower limb arterial disease) HyperTG or TG levels between 150-500 mg/dl on statin therapy Patient informed of the research, not having objected to participation and having provided written consent for genetic analysis  B. Patients with familial hypercholesterolemia (FH) and without hyperTG :  Age > 18 years Mild diagnosis Primary prevention (no coronary artery disease, cerebrovascular disease or lower limb arterial disease) TG <150mg/dl on statin therapy Patient informed of the research, did not object to participation and provided written consent for genetic testing  Exclusion Criteria:  Secondary prevention or planned coronary intervention or cardiac surgery History of acute or chronic pancreatitis Statin-intolerant patient Glycated haemoglobin level greater than 10.0%. Human Immunodeficiency Virus infection on treatment, Use of corticosteroids Severe renal impairment (Glomerular filtration rate < 30 ml/min) Pregnant women