Inclusion Criteria:  Males or females aged between 17 and 60 years who weigh at least 50kg. 17 BloodSafe Ghana Pass pre-donation screening using the NBSG standardised donor screening questionnaire for medical conditions and lifestyle risks for transfusion transmissible infections (Appendix 5). Vital signs must meet the NBSG requirement for blood donation: systolic and diastolic blood pressures between 90-140 mmHg and 60- 90 mmHg, respectively; pulse rate between 50-100 bpm; non-contact forehead temperature not exceeding 37.5°C; meeting acceptable requirements for skin lesions, needle marks and physical appearance. Must be willing and able to give study consent or assent. Intend to remain in the study location/site during the entire length of the study.  Exclusion Criteria:  1. 2. 3. 4. 5. items 1-5 pertain to the clinical trial. All persons who meet ANY of the exclusion criteria will be excluded from participating in the clinical trial.  Persons who have used iron supplementation within the past one month. Participant reports having previously donated blood. Evidence for a TTI at baseline among those who successfully donated. Evidence of Malaria and helminthic infections at baseline Participants who have Hb <10g/dl at screening