Inclusion Criteria:  Male or female subjects 18 years of age or older with 2nd Degree Burn Wounds Injury within the prior 48 hours Subjects must understand and give written informed consent. Subjects must agree to have blood draws performed as per protocol Subjects must be accessible for wound treatment and assessment visits Males and females must agree to use an acceptable method of contraception. Exceptions will be females of non-childbearing age and monogamous males who are partners of females of non-childbearing age. Acceptable methods of birth control include; history of sterilization, oral contraceptives, depo-progesterone injections, a barrier contraceptive such as a condom with or without spermicide cream or gel, diaphragms or cervical cap with or without spermicide cream or gel, or an intrauterine device (IUD).  Maximum wound size limited to:  Single wound: ≤ 5% body surface area (BSA) Multiple wounds treated in a defined anatomical region with ≤ 20% cumulative TBSA as would correspond to a 70kg subject.  Exclusion Criteria:  Solely 1st degree or solely 3rd degree burns Subjects with superficial 2nd degree burn who are expected to heal within 2 weeks post standard therapy Evidence of active infection at the wound site Evidence of significant wound healing prior to treatment Burn wounds requiring skin grafting Wound exclusively located in the area of fingers, toes, face, or perineum Have any requirement for the use of systemic steroids or immunosuppressive Subjects Allergic to human albumin, streptomycin, or penicillin Be a pregnant female or nursing mother Subjects who are known or found to be HIV positive History of alcohol or substance abuse requiring treatment within the past 12 months.  Patients with severe medical conditions  Malignancy (other than non melanoma skin cancer) not in remission or in remission less than 5 years Life expectancy less than two years Severe cardiopulmonary disease restricting ambulation to the clinical facility WBC <3 or > 20 x109/L, Hgb < 7g/dL, platelets count 50x109/L or less, serum creatinine > 2 times the upper normal limit Those with a known history of coagulopathy Subjects who are potential recipients of tissue or organ transplantation Subjects with circulating Hepatitis B antigen and/or who are seropositive for Hepatitis C antibody History of poor compliance, unreliability