Inclusion Criteria:  18 years of age or older. Subject or parents willing and able to give informed consent, and assent as appropriate. Patients who have a clinical diagnosis of CMN with plans for elective non-urgent excision of part or all of their nevus, with nevus surface area of > 6 cm2.  Exclusion Criteria:  Immunosuppressive therapy with glucocorticoid or other systemic immunosuppressant within 4 weeks of recruitment (except for inhaled corticosteroids for asthma). History of malignancy. History of organ transplantation. Known immunosuppressive disease, including infection with HIV. Severe medical comorbidities (diabetes mellitus requiring insulin, CHF of any severity, MI, CVA, or TIA within 3 months of screening visit, unstable angina pectoris, oxygen-dependent severe pulmonary disease) Subject is currently enrolled in another investigational device or drug trial(s), or subject has received other investigational agent(s) within 28 days of baseline visit. Subjects who have known hypersensitivity to SADBE or any of its components. Any condition judged by the investigator to cause this clinical trial to be detrimental to the patient.