Inclusion Criteria:  Probant subjects Minor or adult subject Adult subject or legal guardian for minor subjects agreeing to sign the study consent and biospecimen consent Subject with differentiated thyroid cancer without an identified causative mutation in the BAP1 and DICER 1 predisposition genes Patient affiliated to a valid social security plan  Relative subjects  Adult subjects Subject agreeing to sign the study consent and the biocollection consent Subject with differentiated thyroid cancer or from a family with several cases of differentiated thyroid cancer without a causal mutation identified in the BAP1 and DICER 1 predisposition genes Patient affiliated to a social security plan  Exclusion Criteria:  Subject refusing to participate Subjects with a causal mutation identified in the predisposition genes: BAP1 and DICER 1 Subjects under guardianship, curatorship or safeguard of justice or not socially insured Subjects with another syndromic predisposition to thyroid cancer (Cowden, Werner, PAF)