Inclusion Criteria:  Age > 18 years old Sustained (> 20 minutes) return of spontaneous circulation (ROSC) Comatose (GCS < 9) Time to ROSC > 15'  Exclusion Criteria:  Protected categories (Pregnant women, Prisoners) Anticipated withdrawal of support within 24 hours Traumatic cause of cardiac arrest time from ROSC to inclusion > 1hour Inclusion in any other interventional trial