Inclusion Criteria:  Peritoneal dialysis patients and hemodialysis patients Dialysis length >3 months >18 years old Consented to participate in all aspects of the study  Exclusion Criteria:  Acute complications to hospitalization 1 month prior to the study; Acute or chronic infections, cancer, and other wasting diseases in the past year; Thyroid dysfunction; Acute onset of podagra; Musculoskeletal diseases; Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD); History of hormonal drug use; During pregnancy or lactation; Can not maintain posture and complete the REE test.