Inclusion Criteria:  Diabetes and / or obesity (BMI>=28). Emergency room / emergency ward / EICU; Be able to understand and agree the research protocol and sign the informed consent  Exclusion Criteria:  Pregnant women / lactation period; The estimated survival time was less than 1 year; Long term follow-up is not guaranteed; Failure to comply with the protocol or procedure; The collection of medical behavior data can not complete the de privacy or label after de privacy; Other researchers think that it is not suitable for inclusion