Inclusion Criteria:  Diagnosis for admission is acute myocardial infarction with severity between Killip II III. Age is between 40-75. Participants who are willing to participate in the study and sign the informed consent.  Exclusion Criteria:  Using sedative hypnotic drugs. Blindness or severe cataract. Neurological diseases such as epilepsy, brain injury, or stroke. Severe mental disorder such as major depressive disorder, bipolar disorder, schizophrenia, intellectual disability or substance use disorders. Unable to communicate. Participants who are unwilling to participate in the study or refuse to sign the informed consent. Participants who are not suitable to include in this study, evaluate by PI or Co-PI.