Inclusion Criteria:  Men or women, of legal age, between 18 and 65 years old. With a confirmed parasitological diagnosis of CL in at least one lesion, performed at least through the following methods: 1) microscopic identification of amastigotes in the lesion tissue; 2) diagnosis of leishmania through PCR; 3) positive culture for promastigotes.  Subjects with an injury that meets the following criteria:  Ulcer or nodule with a maximum size of 4 cm (the largest diameter). Not located in the ear, face, near mucous membranes, joints, or in places where, in the opinion of the IP, the administration of the product is difficult to apply topically. Subjects with a maximum of 4 LC lesions. Injury with an evolution of less than 4 months according to the subject's history. Subjects who have given their CI in writing. At the discretion of the IP, the subject is able to understand and comply with the requirements of the study. Subjects who can attend control visits.  Exclusion Criteria:  Women with a positive pregnancy test during the screening process, or breastfeeding, or women of childbearing potential who do not accept the use of contraceptives during treatment and up to 45 days after treatment. History of clinically significant medical problems or treatments that may interact negatively or positively with topical treatment for Leishmaniasis, including any immunocompromising conditions. Within 8 weeks (56 days) of starting the study treatment, having received treatment for Leishmaniasis with any type of medication, including Glucantime that probably, in the opinion of the PI, could modify the course of infection with Leishmania. Based on physical examinations performed, a diagnosis of CML has been or is suspected. Known or suspected history of hypersensitivity or idiosyncratic reactions to study treatment.  Present the following laboratory alterations:  Serum creatinine above normal levels ALT / AST levels 3 times above the normal value (according to the levels reported by the local laboratory). Subjects who do not want to keep study appointments or who cannot keep follow-up visits for up to six months.