Inclusion Criteria:  Availability of written informed consent of the research subject and parents / adoptive parents of the subject to participate in the research; Boys and girls aged 12-17 inclusive; Negative test result for HIV, hepatitis, syphilis; A negative test result for the presence of IgM and IgG antibodies to SARS CoV2 by enzyme immunoassay, as well as, if available, the result of an examination performed in medical institutions of the Moscow City Health Department 7 days prior to inclusion in the study can be taken into account; A negative test result for COVID-2019, determined by the PCR method at the screening visit, and, if available, can be taken into account the result of the examination performed in the medical organizations of the Moscow City Health Department 7 days before being included in the study; No history of COVID-2019; Absence of contact of the research subject with COVID-2019 patients for at least 14 days prior to inclusion in the research (according to the research participant, parents / adoptive parents of the subject); Consent to the use of effective contraceptive methods during the entire period of participation in the study; Negative pregnancy test based on urine test results at the screening visit (for all girls - study participants); Negative test for the presence of drugs and psychostimulants in the urine at the screening visit; Negative alcohol test at screening visit; No history of pronounced post-vaccination reactions or post-vaccination complications after the use of immunobiological drugs; Absence of acute infectious and / or respiratory diseases for at least 14 days prior to enrollment in the study  Exclusion Criteria:  Any vaccination / immunization carried out within 30 days prior to enrollment in the study. Therapy with steroids (with the exception of hormonal contraceptive drugs) and / or immunoglobulins or other blood products, not completed 30 days before enrollment in the study; Immunosuppressive therapy and systemic therapy with corticosteroid drugs, completed in less than 3 months. prior to inclusion in the study. Postponed acute coronary syndrome or stroke less than one year before inclusion in the study Any immunodeficiency (for example, hereditary immunodeficiency, acquired immunodeficiency syndrome [AIDS], etc.).  Infectious diseases:  history of HIV (antibodies to HIV type 1 or 2), positive test for HBsAg or HCV RNA [qualitative]), active form of syphilis; Tuberculosis; Active infection (with the exception of onychomycosis), or any significant episode of infection requiring intravenous antibiotic treatment for 4 weeks before screening or by mouth for 2 weeks before screening; A history of a serious recurrent or chronic infection not listed above. Major surgery within 4 weeks prior to screening. Chronic autoimmune diseases or systemic collagenoses in history, requiring the appointment of immunosuppressive therapy. Volunteers who have undergone organ transplants, including bone marrow or peripheral blood stem cell (PBC) transplants, and are receiving immunosuppressive therapy. History of splenectomy. Volunteers with a previous or concomitant history of neoplasms (ICD codes C00-D09). A burdened allergic history (history of anaphylactic shock, Quincke's edema and other life-threatening conditions), hypersensitivity or allergic reactions to the administration of immunobiological preparations, known allergic reactions to any component of a vaccine or vaccine containing similar components, exacerbation of allergic diseases on the day of inclusion in the study. Neutropenia (decrease in the absolute number of neutrophils less than 1000 cells / mm3), agranulocytosis, significant blood loss, severe anemia (hemoglobin concentration less than 80 g / l), thrombocytopenia (decrease in the absolute number of platelets less than 50,000 cells / mm3). Anorexia, protein deficiency of any origin. Volunteers with a BMI <18 (low body weight) or a BMI ≥ 35 kg / m2. Extensive tattoos at the injection sites (deltoid muscle area), which do not allow assessing the local response to the injection of ILP. Chronic diseases of the cardiovascular, bronchopulmonary, neuroendocrine systems, as well as diseases of the gastrointestinal tract, liver, kidneys, muscle and connective tissue in the stage of exacerbation or decompensation. Presence or suspicion of drug, alcohol or drug addiction and other mental disorders. Diseases, the presence of which, from the point of view of the medical researcher, puts the health of the participant at risk if participating in the study or potentially complicates the interpretation of the results of the examination. Family members of staff of research centers directly involved in the conduct of research, etc. Participation in other clinical trials and use of other investigational drugs within 28 days of screening. Planned vaccination against COVID-19 with any vaccine, both in the framework of other studies and in the framework of civil appeal. Female subjects during pregnancy or lactation Inability to read in Russian; inability or unwillingness to understand the essence of the research. Any other conditions that limit the eligibility of obtaining informed consent or that may affect the volunteer's ability to participate in the study affect the volunteer's ability to take part in the study