Inclusion Criteria:  Common cold: presence of moderate to severe nasal congestion AND moderate to severe runny nose AND at least one (01) of the following moderate to severe symptoms: sneezing, headache, myalgia, sore throat, throat pain, dysphonia, cough and fever.  Duration of symptoms ≤ 48 hours at screening. Informed Consent Form (ICF) signed before carrying out any study procedure.  Exclusion Criteria:  Presence of significant septum deviation, compatible with impaired nasal ventilatory function, at the investigator's discretion. Presence of nasal polyposis to previous rhinoscopy. Known hypersensitivity to any component of the experimental drug formulation. Required antibiotic therapy for upper airway infection treatment