Inclusion Criteria:  Clinical evidence of cerebral small vessel disease or MRI evidence of lacunar infarcts and white matter hyperintensity No disability (modified Rankin's scale < 2) No dementia (MMSE > 24 and absence of dependence in daily activities) Able and willing to consent  Exclusion Criteria:  Contraindications to MRI Standard MRI of bad quality due to movement artefacts Pregnant Unable to tolerate MRI