Inclusion Criteria:  Households must:  Be within the boundary of Sukuta as determined by the 2013 census Have at least 3 members including at least one child under age 18  Individuals must:  Provide signed (or thumbprinted) informed consent for study participation (obtained from a parent or guardian for children under the age of 18 Be willing and have capacity to participate and comply with the study protocol as judged by a member of the study team Be resident in the household, with no plans to move outside of the household during the period of study participation  Exclusion Criteria:  Households:  - Less than 80% of individuals living in the household, as defined by the The Gambia Demographic and Health Survey 2013 definition, provide consent to participate  Individuals:  Consent not provided Has any condition or any other reason that may lead to difficulty or discomfort in obtaining all the necessary samples Is judged by the study team member to be unable or unlikely to participate and comply with the study protocol for the entire study period