Inclusion Criteria  An adult patient with suspected or pathology-proven central nervous system neoplasm. MRI of the brain, positive for at least one intra-axial lesion greater than 5 mm.  Exclusion Criteria  Contraindication to MR imaging. Known allergy to gadolinium-based contrast agents. Renal failure as defined by a GFR less than 30 or the use of hemodialysis. Pregnant. Patients less than 18 years of age will be excluded.