Inclusion Criteria:  Male or female participants 18 and 55 years of age Female participants must be postmenopausal or not of child bearing potential. Participants must weigh 50 kg - 120 kg and have BMI= 18.0-30.0 kg/m2 Participants should be in good health as determined by no clinically significant findings from the medical history, physical examination, vital signs, and ECG. Participant must have laboratory values (including fasting plasma glucose and HgbA1C) within the reference range at the local laboratory At screening, and at baseline visit of each Period, participant has vital signs which are within the protocol defined ranges  Exclusion Criteria:  Women of childbearing potential Sexually active male participant with partner(s) of women of childbearing potential, UNLESS agree to comply with highly effective contraception AND use a condom Participant with significant illness, including infections, or hospitalization within the 30 days prior to dosing. diabetes mellitus or participants with fasting plasma glucose (FPG) levels > 100 mg/dL or >5.55 mmol/L. clinically significant risk of developing diabetes mellitus during the study Use of: tobacco products within 3 months prior to first dosing drug or alcohol abuse within 12 months prior to first dose alcohol within 48 hours prior to the dosing of each treatment period. any prescription or non-prescription, herbal medication, dietary supplements or vitamins during 14 days prior to dosing.. History of : clinically significant hematologic, renal, endocrinologic, pulmonary, cardiovascular, hepatic, or allergic disease, medically documented. including uncontrolled hypertension, interstitial lung disease, or other causes of dyspnea, acute pancreatitis within 1 year of screening or past medical chronic pancreatitis. cardiac disease immunodeficiency diseases malignancy of any organ system carcinoma of the skin or in situ cervical cancer), within 5 years, erythema multiform (EM), Steven-Johnson-Syndrome (SJS) or Toxic Epidermal Necrolysis (TEN). history or presence of any surgical or medical condition which might significantly alter the absorption, distribution, metabolism or excretion of drugs. clinically significant ECG abnormalities or a family prolonged QT-interval syndrome. chronic infection with Hepatitis B (HBV) or Hepatitis C (HCV).  Other inclusion/exclusion criteria may apply