Inclusion Criteria:  Gender: Either gender Age:18 - 65 years of age Patient with portal vein thrombosis documented on imaging (USG with color doppler, CECT abdomen and CEMRI abdomen  Exclusion Criteria:  Patients who do not consent to the study. Patient with pregnancy and lactation Patients with a history of blood transfusions in the last two weeks Patients who are too sick to undergo screening tests. Patients on hemodialysis Chronic heart failure and chronic pulmonary or end-stage renal disease Patients who are on plasma therapy