Inclusion Criteria:  1. Age ≥18 years old and ≤75 years old 2. Rutherford clinical category classification：3,4 or 5 3. Significant stenosis (≥70%) or occlusions of de-novo or restenotic lesion(s) located in below-the-knee arteries which distal bloodflow is patent. 4. Reference vessel diameter is between 2 mm and 4 mm 5. Subject has provided written informed consent prior to participation , understands the purpose of this trail and agrees to comply with all protocol-specified examinations and follow-up appointments.  Exclusion Criteria:  1. Plasma creatinine clearance rate <30 mL/min 2. Acute vessel occlusion or acute thrombosis in target lesion 3. Planned amputation on the target limb 4. Subjects confined to bed that are completely non-ambulatory. 5. Thrombolytic therapy or surgical procedure on the target limb within 6 weeks prior to enrollment. 6. Life expectancy < 5 year. 7. Cumulative length of 100% occluded target lesion(s)>150 mm 8. In-stent restenosis within the target lesion, or the distance between the target lesions and the stent was less than 20 mm 9. History of stroke within 90 days prior to enrollment 10. Known allergy to contrast agents, antiplatelet, anticoagulant, or thrombolytic therapy 11. Uncorrectable bleeding diathesis 12. The lesion of the inflow pathway cannot be identified due to the complete occlusion of the P3 segment of the popliteal artery 13. Pregnant or breastfeeding female subjects 14. Ability to cross a guidewire through target lesion 15. Patients who have participated in clinical trials of other medical devices or drugs during the same period