Inclusion Criteria:  Chronic HCV infection (≥ 6 months). Weighing at least 35 kg. Treatment-naïve children with chronic HCV infection without cirrhosis or with compensated cirrhosis. Parent or legal guardian must provide written informed consent.  Exclusion Criteria:  Patients with comorbidity of chronic medical illness (decompensated heart disease, severe renal impairment (GFR < 30) or ESRD, uncontrolled DM). Concomitant HBV or HIV infection. Medications (Amiodarone, beta-blockers).