Inclusion Criteria:  Persons with various forms of a confirmed diagnosis of atopic dermatitis; The age of the patients is from 18 to 45+ years; Persons of Kazakh nationality, whose paternal and maternal grandparents are Kazakhs. Persons who are able and willing to provide written informed consent; Persons capable and willing to comply with the research protocol;  Exclusion Criteria:  Persons under the age of 18; Patients with severe concomitant systemic diseases, including cardiovascular, respiratory, hepatic and renal failure Patients with severe infectious processes (sepsis, abscess, hepatitis B and C, HIV) Persons with mental illness. Persons taking corticosteroid drugs, immunosuppressants within the last month; Persons who, in the opinion of the researcher, are mentally or legally incapacitated, which prevents obtaining informed consent; Pregnant or lactating women; Tuberculosis of any localization in the active phase and in history; Severe and decompensated diseases of the liver and kidneys, cardiovascular system; Severe and decompensated course of endocrine diseases; Autoimmune diseases; Systemic diseases; Oncological diseases;