Inclusion Criteria:  The onset of symptoms and signs are less than 24 hours Male or female aged from 14 to 60 years No other therapy before grouped Be willing to participate the study and sign the informed consent  Exclusion Criteria:  Stiff neck patients who had diagnosed cervical vertebra or cervical spondylosis Suffered from systemic collagen immune diseases or other acute or chronic infection Use pain-killer drugs may affect the outcome evaluation Refuse to join the trial; Drop out in follow-up visit Aggravation of disease or complications during the study