Inclusion Criteria:  Aged 18-70 years American Society of Anesthesiologists(ASA) physical status of I-III BMI: 18.5-28 kg/m2 Type of operation: elective thoracoscopic lobectomy The patient and/or family members have signed the informed consent -  Exclusion Criteria:  Allergic to local anesthetics or glucocorticoids Preoperative use of opioids Severe coagulation dysfunction Severe heart, lung, liver and kidney insufficiency Used to have immunosuppressive therapies such as radiotherapy, chemotherapy and glucocorticoid, or have immune system diseases Peptic ulcer Perform astrointestinal anastomosis recently Used to have a chest surgery Central nervous system disease or peripheral neuropathy Perioperative blood transfusion Others: such as fracture, wound repair, corneal ulcer, adrenal hypercortical disease, diabetes, pregnant women -