Inclusion Criteria:  Risk of delirium (ICU patients with length of stay (LOS) > 24 hours) Gastric tube or gastrostomy ICU stay ≤ 48h until first study intervention Women: negative pregnancy test, age ≥55 years or status post hysterectomy/bilateral ovariectomy Adult patients (age ≥ 18 years) ≥ 45 kg body weight or BMI ≥18.5  Exclusion Criteria:  Acute liver failure Women: Pregnancy and breast-feeding Pre-existing Delirium Expected longer Deep sedation Wheat allergy, celiac disease or gluten intolerance Religious reasons for alcohol abstinence Dementia or Alzheimer's disease Status epilepticus Terminal state Active psychosis Harmful Alcohol usage or anamnestic status post alcohol abuse ICU admission with intention to short-term postoperative surveillance for 24 hours Brain injury with unconscious state