Inclusion Criteria:  Pregnancies with live birth, 2011-2018 Pregnancies linked to liveborn infants Pregnancies aged 20-45 years at delivery  Exclusion Criteria:  Pregnancies with a chromosomal abnormality Pregnancies with exposure to known teratogenic drugs (e.g. antineoplastic agent, warfarin, lithium, isotretinoin, misoprostol, thalidomide) during the first trimester Pregnancies with no benzodiazepine prescription during the first trimester, but with at least one benzodiazepine prescription during the 3 months before the pregnancy onset