Inclusion Criteria:  age>18 Histological diagnosis of epithelial ovarian cancer Patients eligible for surgery Patients followed in the clinical care pathway c / o oncological gynecology (surgery and follow up) informed consent  Exclusion Criteria:  Patients with HCV, HBV and HIV Patients with other malignancies diagnosed less than 5 years prior to the diagnosis of ovarian malignancy Ovarian metastases of primary neoplasms of other organs Presence of ascites for non-neoplastic causes