Inclusion Criteria:  Signed informed consent Patients after uncomplicated acute coronary syndrome of both sexes. Patients completing a maximal or symptom-limited CPET without angina or electrical ischaemia. Age equal to or less than 72 years.  Exclusion Criteria:  Refusal of informed consent Advanced biological age. Kidney failure (GFR < 30ml/min/1.73 m2). Liver failure (GOT >2 times normal value). Ejection fraction less than 50%. Uncontrolled blood pressure (>140/90 mmHg). Uncontrolled heart failure. Dissecting aortic aneurysm. Uncontrolled ventricular tachycardia or other dangerous ventricular arrhythmias. Aortic or mitral valve disease. Recent systemic or pulmonary embolism. Active or recent thrombophlebitis. Acute infectious diseases. Uncontrolled supraventricular arrhythmias or tachycardia. Repeated or frequent ventricular ectopic activity. Moderate pulmonary hypertension. Ventricular aneurysm. Uncontrolled diabetes, thyrotoxicosis, myxedema, Conduction disorders such as: complete atrioventricular block. Left bundle branch block. Wolf-Parkinson-White syndrome. Fixed rate pacing. Severe anaemia. Psychoneurotic disorders. Neuromuscular, musculoskeletal and arthritic disorders that may limit activity. may limit activity.