Inclusion Criteria:  Age 18 yy Patient planned for minor hepatectomy Signed informed consent  Exclusion Criteria:  Pregnancy Cirrosis ASA>3 Elevated liver enzymes AV-block >1, without pacemaker WHO class >2 Allergy against Lidocain or other amid-type local anasthesia Heart failure Epilepsy Treatment with class III anti-arythimic medication Preoperative ongoing opioid usage Use of : Erythromycin, clarithromycin, Fluvoxamine, Cimetidine, ciprofloxacin, antivirala-HIV-läkemedel or imidazol the week before surgery.