Inclusion Criteria:  Age ≥19 years old Patients requiring PCI with coronary de novo lesions Patients with stable angina pectoris, or unstable angina pectoris, and asymptomatic myocardial ischemia Women of childbearing age who agreed to use one or more of the clinically appropriate methods of contraception during the trial period. In case of voluntarily deciding to participate in this clinical trial by signing the informed consent form  Inclusion criteria for coronary angiography  Patients with significant coronary artery stenosis including left main coronary lesion (> 50% diameter stenosis on coronary angiography) On coronary angiography, the length of the lesion is less than 34 mm and the diameter of the reference vessel of the coronary artery is 2.0 - 4.0mm.  Exclusion Criteria:  Patients have restenosis lesions with or without thrombosis Patients with Infarct related artery (IRA) lesions among patients with acute myocardial infarction Patients who are contraindicated in aspirin, heparin, ticagrelor, iopromide, clopidogrel, prasugrel and paclitaxel Patients with platelet aggregation or disorders at risk of increased bleeding, such as gastrointestinal ulcers, which limit platelet aggregation inhibitory therapy and anticoagulant therapy Patients with a left ventricular ejection fraction of less than 30% on echocardiography Patients with renal insufficiency (eGFR<30mL/min) Patients with a history of cardiogenic shock Pregnant or lactating women The patients have a life expectancy of less than 12 months Patients who have or currently have medical conditions such as psychiatric disorders that significantly affect this clinical trial Patients who, in the investigator's judgment, may not be suitable for this clinical trial or may increase the risk associated with participation in the study Patients who are currently participating in other clinical trials or have experience participating in other clinical trials within 90 days from the screening date Patients who are unsuitable for the study according to the investigator judges  Exclusion criteria for coronary angiography  Patients with left main coronary lesion Patients with graft vessel lesion Patients who cannot apply pre-dilation or fail in pre-dilation to apply medical devices for clinical trials  Patients with one of the following items after pre-dilation of the target lesion  When FFR (Functional measurement) is measured ≤ 0.8 in large vessels (only for cases with a diameter of 3.0 mm or more) Patients who need stenting due to vascular dissection that restricts blood flow Residual stenosis > 30% TIMI flow < 3