Inclusion Criteria:  Over 19 ages healty men Over 50.0kg, 18.0kg/m2 ≤ BMI ≤30.0kg/m2 Men who dont have congenital disease and other cronic disease need to be cared etc.  Exclusion Criteria:  Men who have congenital liver disease (AST, ALT, CK ≥ 2X ULN) Men who have drunken or eatten something including carffeine within 24 hours before etc.