Inclusion Criteria:  Male and non-pregnant female human subjects, age 18 - 45 years. Body Mass Index between 18.5-30 Kg / m2 . Subjects with normal findings . Willingness to follow the protocol requirements  Exclusion Criteria:  Known history of hypersensitivity to Nefopam, Paracetamol or related drugs. Requiring medication for any ailment having enzyme-modifying activity in the previous 28 days, prior to dosing day. Subjects with a history of convulsive disorders. Subject with a moderate or severe renal impairment History of cardiovascular, renal, hepatic, ophthalmic, pulmonary, neurological, metabolic, haematological, gastrointestinal, endocrine, immunological or psychiatric diseases. Female subjects not confirming to using birth control measures,