Inclusion Criteria:  Patients Who have Completed trial of RH-107-001 (previously treated patients) Previously received Recombinant Human Coagulation Factor VIII-Fc prophylactic. The patient and/or guardian or his or her legal representative must be able to read, understand, and provide signed informed consent, And voluntarily signed the Informed Consent Form. The compliance of patients appeared quite well. Patient who is considered by the investigators suitable for ongoing to accept previously treated.  Exclusion Criteria:  Subjects who have not completed trial of RH-107-001or who have completed the Phase III clinical trial but not willing to continue receiving treatment. Subjects who did not participate in the Phase III clinical trial of RH-107-001.