Inclusion Criteria:  Has completed and signed an appropriately administered Informed Consent Form (ICF) prior to any study-related procedures. Subjects less than 18 years of age (or as required by state law) must sign an Assent Form for the study and a parent or legal guardian must sign the ICF.  Has facial acne vulgaris with:  20 to 50 inflammatory lesions (papules, pustules, and nodules) 25 to 100 non-inflammatory lesions (open and closed comedones) No more than 2 nodules on the face IGA score of moderate (3) to severe (4) Willing to use only the supplied non-medicated cleanser (Cetaphil Gentle Skin Cleanser) and to refrain from use of any other acne medication, medicated cleanser, excessive sun exposure, and tanning booths for the duration of the study.  Exclusion Criteria:  Acne conglobata, acne fulminans, secondary acne (chloracne, drug-induced acne), or any dermatological condition of the face or facial hair (eg, beard, sideburns, mustache) that could interfere with the clinical evaluations. Sunburn on the face.