Inclusion Criteria:  Patients  > 16 years of age COVID-19+ test  Antibody Negative/Presumed COVID-19 comparator cohort  > 16 years of age NO COVID-19+ test (either by nasal swab or antibody) Experienced symptoms Strong epidemiologic links suggesting probable COVID-19 infection (such as household or occupational contacts and close timing of their symptoms to an index case.  Caregiver:  1. Family caregivers of hospitalized COVID-19+ patients who are participating in the study. Family caregivers are defined as the family member or friend who is responsible for providing and/or coordinating all the COVID-19 survivors' post-hospital care without financial compensation. They will be included if they are able to read and speak English and are over the age of 18 years.  Exclusion Criteria:  Anticipated death or withdrawal of life sustaining treatment within 48 hours. Catastrophic neurological injury in the opinion of the attending physician (e.g. Grade V SAH or massive CVA). Patient unlikely to comply with follow-up. Physician refusal (only for hospitalized patients). Patient or SDM (substitute decision maker) refuses consent. No next of kin or SDM available (if patient unable to provide consent).