Inclusion Criteria:  Patients over 18 years old Diagnosis of acute myeloid leukemia with CBF confirmed by cytogenetics (karyotype and / or FISH): t (8; 21), inv (16) or t (16; 16) and / or molecular biology (RUNX1-RUNX1T1 fusions or CBFB-MYH11) Initial management by intensive chemotherapy, hypomethylants or targeted therapies  Exclusion Criteria:  - Opposition expressed to research