Inclusion Criteria:  Physical status I and II according to the American Society of Anesthesiologists (ASA) Undergoing elective laparoscopic cholecystectomy  Exclusion Criteria:  refuse to participate Present inability to communicate due to altered level of consciousness or due to the presence of neurological or psychiatric illness Present contraindication to the use of any of the drugs employed in the study Present history of alcohol or drug addiction Body mass index (BMI) ≥ 35 Presence of chronic pain or use of opioids.