Inclusion Criteria:  LDL cholesterol level ≥ 160 mg/dL (corrected for LP(a))  Metabolic syndrome as defined by ATPIII-criteria: at least 3 of the following 5 criteria, but certainly high blood pressure:  Blood pressure ≥ 130/85 mg Hg or blood pressure medication (arterial hypertension) Waist circumference > 102 cm for men or > 88 cm for women Triglycerides ≥ 150mg/dL HDL cholesterol < 40mg/dL for men or < 50mg/dL for women Fasting glucose ≥ 110 mg/dL  Exclusion Criteria:  <18 jaar >70 jaar Smoking Use of nutritional supplemenrs Use of cholesterol lowering medication or other medication except for blood pressure medication Triglycerides > 400 mg/dL > 2 alcoholic consumptions/day Chronic illness (e.g. diabetes, atherosclerosis, reumatoid arthritis) Acute infection Current pregnancy or pregnancy wish during the study period Breast feeding  When nutritional supplements were used regularly, participation is allowed after a 10-day wash out period. Subjects who used cholesterol lowering medication or nutritional supplements with red yeast rice, can participate after a 6-week wash out.