Inclusion Criteria:  Male or female aged≥ 18 years Signed informed consent  Body mass index:  25 kg/m² ≥ BMI ≥ 18,5 kg/m² (lean subjects) >30 kg/m2, with waist-to-hip ratio >0.9 (subjects with obesity) Person who is affiliated to a social security scheme or who is a beneficiary of such a scheme  Exclusion Criteria:  Any chronic disease with vascular impact (including type 2 diabetes) Active tobacco use (any quantity) Participant involved in another interventional clinical study History of hypersensitivity reaction to products used The persons mentioned in articles L1121-5 to L1121-9 of the public health code may not be included in this research (Pregnancy or Lactation ; Females with childbearing potential, defined as a premenopausal female and not using an effective form of birth control. (Effective birth control methods include: oral, implant or patch hormone contraception; intrauterine device; abstinence and outercourse; tubal ligation; vasectomy.) ; Person deprived of liberty by judicial order ; Person under guardianship or curatorship ; Minors ; Adults who are incapable or unable to give their consent ; Cross-over situations) Subject who would receive more than 4500 euros in compensation due to his or her participation in other research involving the human person in the 12 months preceding this study