Inclusion Criteria:  Age of the patient when ACS occurs (between 18 and 50yo for men, between 18 and 55yo for women) Written informed consent  Exclusion Criteria:  Men <18yo or >50yo Women <18yo or >55yo ACS causes (toxic, coronary dissection) Congenital cardiac malformations Familial hypercholesterolaemia Pregnancy, breast-feeding women or vulnerable profile. Patient refusal to participate or previously included in a clinical research trial.