Inclusion Criteria:  Adult patients [18-89 years of age] Present to the Emergency Department With symptoms suggestive of COVID-19 or respiratory infection Whose assessment includes CBC-Diff and RT-PCR testing  Exclusion Criteria:  Pregnancy Prisoners <18 years of age >89 years of age Previously evaluated in this study No RT-PCR testing Sample age >2 hours from time of draw Instrument flags, including vote outs and review flags for the MDW parameter Samples stored in refrigerated temperatures