Inclusion Criteria:  Patients who meet the criteria of either Group I OR Group II are eligible.  Group I  Patients with signed informed consent and who satisfy all of the following criteria will be included:  20 years old or older (regardless of sex) Outpatients Newly-diagnosed with dry eye disease (DED) within 6 months prior to signing the informed consent under hospital-based practice in Taiwan  Group II  Patients with signed informed consent and who satisfy all of the following criteria will be included:  20 years old or older (regardless of sex) Outpatients  Patients who had undergone cataract surgery and  was suspected to have dry eye disease (dry eye evaluations conducted based on the routine practice) within 6 months prior to signing the informed consent or was diagnosed with dry eye disease within 6 months prior to signing the informed consent  Exclusion Criteria:  Patients who meet ANY one of the following criteria are not eligible.  Patients who have ocular comorbidities, and appear dry eye sign and symptoms that interfere with diagnosis of dry eye disease (DED) Patients who cannot confirm subjective symptoms of dry eye Patients who cannot read or write, and/or could not understand dry eye questionnaire appropriately which may compromise the accuracy of questionnaire score. Patients who participate in other interventional trials in the past 30 days