Inclusion Criteria:  Healthy men aged between 18 to 55 years (incl). Body mass index 18.5-30 kg/m² (incl). No signs of acute or chronic disease during the screening. Laboratory blood and urine values are within the normal range or within 10% of the normal range of deviations and are considered by researchers to be clinically insignificant. Non-smokers or ex-smokers (defined as completely quitting smoking for at least three months prior to being included in the test). No known history of alcohol abuse, intake of fewer than 10 units of alcohol per week (1 unit of alcohol is equivalent to ½ liter of beer, 200 ml dry wine, or 50 ml of spirits). No known history of drugs abuse at least 6 months prior to being included in the test (benzodiazepines, opioids, cocaine, barbiturates, marijuana, amphetamine). Willingness to comply with the protocol requirements regarding the restriction of the consumption of foods as well as requirements regarding the intake of food, fluids, and physical activity imposed by the study. Xanthine-containing products (coffee, tea (including tutsan tea), chocolate, cola, cacao, energy drinks, etc.) should be excluded from the diet for at least 48 hours before taking the drug. Products containing tobacco, alcohol-containing products and beverages, concentrated fruit and vegetable juices, grapefruit and/or its juice, other citrus fruits and drinks containing quinine, food containing poppy, fatty, spicy and smoked foods should be excluded at least 72 hours before taking the drug. Cruciferous vegetables (broccoli, Brussels sprouts, cauliflower, kohlrabi, as well as white and red cabbage, savoy, and Chinese cabbage) should be excluded at least 7 days before taking the drug. Healthy subject according to medical history, physical examination, and assessment of basic vital signs. No significant abnormalities on 12-lead ECG. No significant abnormalities on the chest X-ray that was performed within 12 months prior to the start of the study. Volunteer's consent to use two medically effective methods of contraception, at least one of which is a barrier method (from the date of screening to the completion of the study and within 10 weeks after the last dose of drugs). The subject's voluntary willingness to provide written informed consent. The ability, at the judgment of the researcher, to follow all the requirements of the protocol.  Exclusion Criteria:  Burdened allergic history. Contraindications for use or hypersensitivity to the active substance or excipients that are part of any of the investigational drugs. The medical need in taking CYP3A4 inhibitors (ketoconazole, ritonavir, itraconazole, erythromycin, clarithromycin), CYP3A4 inducers (rifampicin, dexamethasone, phenytoin, carbamazepine, phenobarbital), within 30 days before the start of the study, including injection of a depot or implant of any drug less than 3 months before the start of the study. Use of any over-the-counter or prescription drugs (including vitamins, minerals, herbal drugs, in particular containing tutsan), use of any dietary supplements less than 14 days before the day of taking the study drug, and throughout the study. Any medical or surgical intervention in history that could disrupt the activity of the hematopoietic system, gastrointestinal tract, urinary, and other body systems. History or presence of significant urinary, cardiovascular, pulmonary, neuroendocrine, immunological, neurological, hematological, gastrointestinal, and other body systems, visual organ, or psychiatric disease or disorder. Any hereditary disease. Participation in any clinical studies less than 90 days prior to the beginning of the current clinical study. Oncological disease at present or in history. Any blood/plasma donation and/or bleeding in the amount of 450 ml, as well as if the volunteers were transfused with whole blood or its components less than 60 days before the start of the study. History or presence of clinically significant hemostasiological disorders or bleeding. Acute infections less than 4 weeks before the start of the study, as well as a positive test result for HIV, syphilis, HBV, and HCV. Positive breath test for alcohol and urinalysis for drugs. Swallowing problems in medical history. Use of prohibited foods and drinks. Subjects with abnormal heart rhythm (HR at rest ≥ 100 bpm or ≤ 50 bpm) and BP (systolic BP ≤100 mmHg or diastolic BP ≤60 mmHg or systolic BP ≥140 mm Hg or diastolic BP ≥ 90 mmHg) on the day of the examination or in the history. Difficulty with taking blood for tests. The values of the parameters of the laboratory and instrumental findings are beyond the normal range (over 10% of the normal range of deviations) or are considered by researchers to be clinically significant. Vegetarianism or any other type of diet.