Inclusion Criteria:  Persons with bronchial asthma confirmed by a doctor; The age of the patients is from 5 to 60 years; Persons of Kazakh nationality, whose paternal and maternal grandparents are Kazakhs. Persons who are able and willing to provide written informed consent; Persons capable and willing to comply with the research protocol;  Exclusion Criteria:  Persons who, in the opinion of the researcher, are mentally or legally incapacitated, which prevents obtaining informed consent; Pregnant or lactating women; Tuberculosis of any localization in the active phase and in history; Severe and decompensated diseases of the liver and kidneys, cardiovascular system; Severe and decompensated course of endocrine diseases; Autoimmune diseases; Systemic diseases; Oncological diseases;