Inclusion Criteria:  Patients ≥ 18 years old with a BMI ≥ 27 kg/m2 who have paroxysmal AF with a ≥ 10% burden on ambulatory monitoring or a previous electrical cardioversion or early persistent AF (≥ 7 days, < 3 months) who are willing to attempt rhythm control.  Exclusion Criteria:  Unable to consent, a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, history of allergic reaction to Semaglutide or any of its components, currently pregnant or planning to become pregnant or currently breastfeeding, history of acute pancreatitis, history of pancreatic adenocarcinoma, previous or current GLP-1 RA use, previous or current use of alternative pharmacologic weight loss agents (phentermine, dithylpropion, orlistat, phentermine-topiramate, bupropion-naltrexone, gelesis100, or setmelanotide), unable to tolerate anticoagulation, history of bariatric surgery.