Inclusion Criteria:  Sub-population A: Adults seeking care or testing for COVID-19  Age ≥ 18 years old Positive RT-PCR or antigen test for SARS-CoV-2 in an upper respiratory specimen (e.g., nasopharyngeal swab, oropharyngeal swab, mid-turbinate swab, anterior nares swab, or nasopharyngeal wash/aspirate)  Sub-population B: Adult Contact of SARS-CoV-2 infected Individual  Age ≥ 18 years old Contact of an individual with confirmed SARS-CoV-2 infection as defined as residing in the same household or residential care facility as a SARS-CoV-2 confirmed case.  Exclusion Criteria:  Sub-population A: Adults seeking care or testing for COVID-19  Hospital admission at the time of enrollment Laboratory confirmed SARS-CoV-2 infection between 10 to 90 days prior Absence of informed consent Individuals who the study investigators believe are unable to comply with the requirements of the study  Sub-population B: Asymptomatic Contact of SARS-CoV-2 infected Individual  Symptoms attributed to COVID-19 as assessed by the investigator Positive RT-PCR or antigen assay for SARS-CoV-2 in an upper respiratory specimen (e.g., nasopharyngeal swab, oropharyngeal swab, mid-turbinate swab, anterior nares swab, or nasopharyngeal wash/aspirate). Hospital admission at the time of enrollment Absence of informed consent Individuals who the study investigators believe are unable to comply with the requirements of the study