Inclusion Criteria:  Children age 5 to 17 years of age who are undergoing port-a-cath access Pre-intervention Children's Fear Scale score of at least 1 with respect to the impending port-a-cath access  Exclusion Criteria:  Subjective report of motion sickness within past 12 months (excluding anticipatory nausea a child may experience en route to their medical appointment) Subjective history of claustrophobia Requires timely antimicrobial therapy Visual, auditory, or cognitive impairment or language barrier precluding comprehension of study-related tasks or safe interaction with VR Medical record documentation of current MRSA infection Subjective history of concurrent respiratory infection (defined as cough, sore throat, fever, coryza, or sneezing within the past 24 hours) or gastrointestinal infection (defined as any vomiting or diarrhea within past 24 hours) Previous enrollment in study Seizure disorder History of vertigo or neurological disorder that creates moderate to severe dizziness.