Inclusion Criteria:  IRB-approved informed consent, age 18 years or older, male or female, anyone considering COVID-19 vaccination or anyone that has received COVID-19 vaccination. Subjects can enroll at anytime after vaccination even though they may not have enrolled before vaccination. For individuals previously tested at Plexision for other purposes, and who have since been vaccinated, residual cells stored for quality control and potential repeat testing will be used to establish earlier measurement of cellular and antibody immunity as described in Table 1.  Exclusion Criteria:  Failure to provide informed consent