Inclusion criteria:  The subject's infertility factors are only male factors and/or fallopian tube factors; Age: 21/28/35/42/49 years old (calculated according to the birthday month of the Gregorian calendar, no more than 6 months before and after); Body mass index (weight/height square)=23～25kg/m2; The menstrual cycle is 28+/-1 days (that is, the menstruation is 2-3 days in advance of each month), and the consistency of the past 6 consecutive months (not more than 1 day before and after, that is, 27-29 days); Women with a history of pregnancy are preferred; Asexual life during the study period; No IUD is placed in the uterine cavity; Volunteer to participate in the experiment and sign the informed consent form.  Exclusion criteria:  Women who have a history of miscarriage; Women during pregnancy and breastfeeding; Mentally ill; Those who have had oral contraceptives or hormonal drugs in the past three months; Combined with serious primary diseases such as cardiovascular, cerebrovascular, liver, kidney and hematopoietic system; Subjects who have participated in other drug clinical trials within six months; Those who have poor compliance and the investigator thinks it is inappropriate to participate in this clinical trial.