Inclusion Criteria:  • Age >18 years.  Diagnosis of stage I, II, III or IV squamous cell carcinoma, nasopharyngeal carcinoma. Measurable disease on CT scan at baseline. Planned to receive radiotherapy with a total dose 60 grays or more divided on 30 fractions with or without cisplatin (100 mg/m2, administered intravenously every 21 days for three cycles or 40 mg/m2 administered weekly for up to 7 weeks). Adequate liver function (liver transaminases level < 3 times upper normal limits and total bilirubin < 1.5 times upper normal limits). Adequate kidney function (estimated glomerular filtration rate >60 ml/min). Adequate bone marrow function (WBCs count > 3000 cells/mm3, ANC count >1500 cells/mm3 and platelets count > 100,000 cells/mm3).  Exclusion Criteria:  ● Diagnosis of Thyroid cancer.  Presence of other primary cancers. Treatment with alpha lipoic acid for any other indication. Allergy to alpha lipoic acid. Pregnant or lactating women.