Inclusion Criteria:  Willingness to take CBD and to participate in follow up for two months Older than 21 and younger than 60 Under antiretroviral therapy for 5+ years and suppressed viral load (CD4 count <350cells/ml)  Exclusion Criteria:  Conditions/medications that may impair the immune response (e.g. rheumatoid arthritis, cancer, diabetes, chronic infections, CAD (Cold agglutinin disease), cellulitis, autoimmune diseases such as lupus, sarcoidosis All medications that may affect inflammation such as aspirin, steroids, statins); CD4 count <350cells/ml), pregnancy, and current marijuana or CBD use (urine drug screen) UF(University of Florida)/Shands staff and students will not be considered for enrollment