Inclusion Criteria:  Age ≥ 18 years. Patient hospitalized in surgical intensive care unit for COVID-19 infection.  Exclusion Criteria:  Pregnant or breastfeeding women CHILD B or C cirrhotic patients Moribund patients with an estimated life expectancy of less than 48 hours on admission to the ICU Subject protected by law under guardianship or curatorship No affiliation to a social security system Absence of signed consent