Inclusion Criteria:  Idiopathic PD Consent to undergo colonoscopy  Exclusion Criteria:  perforation or obstruction of gastroenteric tract, radiotherapy of abdomen or pelvis region severe heart, liver or kidney failure coagulation disorders immunity disorders current viral, bacterial or fungal infection abdominal aortic aneurysm qualifying for surgery, pregnancy and lactation treatment with Duodopa, deep brain stimulation or apomorphine colonoscopy confirmed colon polyps, except for lesions <5 mm qualified for the NBI International Colorectal Endoscopic I group or other potentially neoplastic lesions after evaluation in white light and narrow beam imaging (NBI) severe food allergy with a history of anaphylaxis after consumption of the product.