Inclusion Criteria:  Histologically proven lung and breast cancer patients indicated for cisplatin (4-6 cycles) Normal baseline serum creatinine levels Normal baseline audiometry Age between 18-70 years  Exclusion Criteria:  Patients with more than one type of cancer Patients with prior chemotherapy treatment Treatment with statins within 12 months before assignment Treatment with fibrates within 4 weeks before assignment Pregnancy and Lactation Abnormal liver function tests or blood count