Inclusion Criteria:  Patients aged ≥18 years. With a diagnosis of Adult Rheumatoid Arthritis according to the 2010 ACR / EULAR criteria. Who have received at least one of the doses of the study drugs. In follow-up in the consultations of the UGC of Rheumatology of the HUVM. With at least two complete evaluations (baseline and final) of clinical variables.  Exclusion Criteria:  Patients where the medical records lack sufficient baseline and final variables to perform the analysis. Patients in whom more than 50% of the variables to be collected are missing in the data collection.