Inclusion Criteria:  Radiological diagnosis of Osteoarthritis according to Kellgren and Lawrence Criteria stage II-III.  Radiological grading of osteoarthritis of the knee determined by qualified radiologist using MOAKS scoring system. Primary osteoarthritis not responsive to conventional treatment and physiotherapy. A minimum pain score of 5 on an 11-point numerical scale. Age >55 years  Exclusion Criteria:  Pregnancy and breast feeding. Knee symptom due to other condition like tumor or referred pain from lumbar spine. MRI confirmed displaced meniscal tear MRI confirmed Grade IV chondral loss. Previous knee surgery within the last 12 months. Previous intra-articular injectable therapies within the last 6 months History of severe systemic illness. Active neoplasm under treatment in the last 12 months- Health conditions including known allergy to local Bleeding tendency.