Inclusion Criteria:  30-75 years old, all genders; At least two main vessels or their main branch vessels have obvious stenosis (≥50%) according to the coronary angiography; Received stent implantation and incomplete revascularization (incomplete revascularization: at least one vessel whose a diameter> 2.0 mm and at least one lesion with a stenosis> 50%, after PCI); eGFR<60ml/min·1.73m2; Willing to be treated and followed-up during the specified time of the study; Signed the informed consent approved by the Ethics Committee  Exclusion Criteria:  Patients with high-risks according to the exercise rehabilitation risks of patients with heart disease by AACVPR; Severe cardiac insufficiency or cardiogenic shock; Combined with severe ventricular arrhythmia, ICD is required; Combined with severe pulmonary hypertension, chronic obstructive pulmonary disease, severe infectious disease, blood system disease, malignant tumor, severe liver damage, etc.; Nervous, mental and motor system diseases; Unwilling to be followed-up.