Inclusion Criteria  Diagnosis of chronic musculoskeletal joint pain (arthritis, traumatic arthritis, osteoarthritis) Adults ages 18 and over. Medically stable without significant medical illness that would preclude treatment with either pharmacologic agent. Have a safe, stable, living environment.  Exclusion Criteria  Unable to consent for research project. Individuals less than 18 years of age. Individuals with rheumatoid or other autoimmune types of arthritis. Individuals diagnosed with SUD especially cannabis, as this may confound results.