Inclusion Criteria:  Patients admitted to the intensive care units of Saint-Antoine, Tenon and Pitié-Salpêtrière hospitals (Paris, France) With moderate to severe respiratory distress syndrome and SARS-CoV-2 infection confirmed by RT-PCR from a nasopharyngeal swab informed and not opposed to participation in research included within 4 hours following the paatient's admission  Exclusion Criteria:  Patients under guardianship / curatorship Patients under AME