INCLUSION CRITERIA  Preoperative:  Female gender Age ≥ 18 years Breast cancer N+ Conservative Surgery: Lumpectomy or Quadrantectomy Berg levels 1-2 axillary lymphadenectomy  Intraoperative:  Axillary incision separated from the incision for the breast lesion Placement of a closed low pressure suction drain in the axillary fossa Hemostasis and lymphostasis using clips, electrocautery, electric scalpel or bipolar coagulation  Postoperative:  - Patients with ≥ 10 axillary nodes removed  EXCLUSION CRITERIA  Preoperative:  Mastectomy Previous radiation therapy Previous axillary emptying Liver pathology Diabetic decompensation: defined as any episode that has required medical attention in an emergency service or hospital admission; and also that which has required a modification of the patient's drugs, or an increase of more than 20% of the total daily dose. Known allergies to any component of Hemopatch (proteins of bovine origin or PEG) Psychiatric disorder that conditions the non-understanding of the questionnaire, or incapacitation of the patient to understand it Simultaneous participation in another clinical study PCR positive for SARS-CoV-2  Intraoperative:  Level 3 axillary dissection (severe axillary involvement) Unexpected surgical contraindication Hemostasis and lymphostasis: ultrasonic techniques or other advanced energy techniques are excluded. Use of fibrin sealants (eg: Tisseel, Artiss, Tachosil), cyanoacrylate type adhesives (eg: Glubran-2) or other types of products (oxidized cellulose format, powders or gelatin sheets or collagen).