Inclusion Criteria:  Adults over 19 and under 80 years of age. Patients who first administered Sarpogrelate hydrochloride drugs or less than 3 months to improve ischemic symptoms such as ulcers, pain, and coldness caused by chronic arterial obstruction (Burger's disease, obstructive arteriosclerosis, diabetic peripheral angiopathy, etc.). Patient who voluntarily signed a written consent form approved by the Clinical Trial Review Committee or Ethics Committee and agreed to participate in the study by the patient or the subject's agent.  Exclusion Criteria:  Patient who is expected to have less than two years of life expectancy. Patient who have bleeding within a week of participation in the study Patient suffering from diseases that may increase bleeding during study participation (hemophilia, capillary placebo, digestive tube ulcer, urinary tract bleeding, hemoptysis, hyperself-bleeding, etc.). A female patient who is likely to be pregnant or pregnant. Female patients who are lactating or are scheduled to be lactated at the time of participation in the study. Patients with severe renal disease and liver disease.