Inclusion Criteria:  Histologically-confirmed diagnosis of colorectal cancer (any stage). Age >18 years at the time of diagnosis. Availability of clinically-annotated radio-imaging data and/or diagnostic Formalin-Fixed Paraffin Embedded (FFPE) blocks (surgical resections and/or tumor biopsies), or at least 10 slides (preferably 20). FFPE tissue blocks are always preferred to slides. Verification that the patient could not be reached for informed consent in accordance with applicable national regulations.  Exclusion Criteria:  if inclusion criteria are not met