Inclusion Criteria:  Consensus of Chinese Experts on the Clinical Diagnosis and Treatment of Intrauterine Adhesions, i.e., patients with previous history of induced abortion and other intrauterine operations, accompanied by periodical abdominal pain, fewmenorrhea, amenorrhea, recurrent abortion, infertility, and uterine adhesions found by hysteroscopy, who have fertility requirements; According to the American Reproductive Society prognostic classification, the AFS score was moderate to severe intrauterine adhesions, that is, the score range was 5-12 points; Patients ranged in age from 18 to 42 years old; normal endocrine function and ovulation; Patients had comprehensive clinical data and were followed up after surgery.  Exclusion Criteria:  Patients with severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction and other systemic diseases; Patients who recently received female genital surgery or underwent high uterine flexion and were unable to receive hysteroscopy and surgical treatment; Amenorrhea, recurrent abortion and infertility caused by other factors such as neuro-endocrine system disorders or congenital abnormalities of reproductive structure and development; Patients with allergic reaction to estrogen and other drugs; Severe abnormal semen of the spouse.