Inclusion Criteria:  Male or female healthy volunteers, age 18 to 55 years, inclusive Body mass index (BMI) 25.0- 40.0 kg/m2 Able and willing to provide written informed consent prior to entry into the study  Exclusion Criteria:  Women who are pregnant or breastfeeding History of diabetes or use of medications for the treatment of diabetes, or hyperglycemia or HbA1c ≥ 6.5% History of pancreatitis or hypersensitivity reaction to GLP-1 analogues