Inclusion Criteria:  Kidney transplant recipients ≥18 years old About to receive a post mortal or living donor renal transplant written informed consent (is able to read of understand in Dutch)  Immunological high risk for rejection  Luminex positive DSAs ; or Retransplantation with repeated mismatch ; or Husband to wife donation (after fathering children); or Offspring to mother donation  Exclusion Criteria:  No immunological high risk