Inclusion Criteria:  Age 18 to 60 years women; have a history of sexual life for 3 years or more; women not in the menstrual period, pregnancy, or puerperium.  Exclusion Criteria:  Women who received antibiotics and antifungal treatment within one month before the sample collection (records); Women suffering from the following diseases: other cancer, vaginal infections, bacterial vaginosis, vulvar infections, urinary tract infections or sexually transmitted infections including chlamydia, gonorrhea, trichomoniasis and genital herpes, type I or type II diabetes, AIDS Virus positive; Women with abnormal vaginal secretions or dirt in the vagina, and women who used flushing substances within three weeks before the sample collection; Have sexual intercourse or use vaginal lubricant within 48 hours before sample collection.