Inclusion Criteria:  Age 1 to ≥80 years old  Exclusion Criteria:  Heart failure or unstable ischemic cardiopathy Chronic obstructive pulmonary disease or respiratory insufficiency Coagulopathy Diabetes mellitus type II with vascular complications Hepatic cirrhosis Kidney failure (Creatinine >1.5 mg/dL o glomerular filtration <30 ml /min) Active neoplasm Pregnancy Gluten-free diet without CD diagnosis