Inclusion Criteria:  Patient with symptomatic, severe aortic stenosis who are not recommended by the heart team for immediate treatment with surgical or transcatheter aortic valve replacement. Patient is willing to comply with scheduled visits and tests and is able and willing to provide informed consent.  Exclusion Criteria:  Severe aortic regurgitation. Anatomic contraindications. Coronary, carotid, or vertebral artery disease that, in the opinion of the heart team, should be treated; or treatment of coronary artery disease ≤ 1 month prior to index procedure. Aortic balloon valvuloplasty ≤ 3 months prior to index procedure. Stroke ≤ 12 months prior to index procedure. History of a myocardial infarction ≤ 6 weeks prior to index procedure. Patients with clinically significant abnormality in cell blood count, history of bleeding diathesis or coagulopathy. Hemodynamic instability. Hypertrophic cardiomyopathy with obstruction. Left ventricle ejection fraction <30%. Ongoing severe infection, including endocarditis, or sepsis. Life expectancy ≤ 12 months.