Inclusion Criteria:  1. An adult who underwent endoscopic/laparotomy Hepatectomy of living donor, Pylorus preserving pancreaticoduodenectomy, Renal allograft, Flexible ureterorenoscopic removal of calculus of upper ureter with regular surgery  Exclusion Criteria:  1. Subjects at risk of bleeding due to esophageal probe, and past cranial, esophageal varicose veins surgery.