Inclusion Criteria:  Histologically confirmed cT0-4 breast cancer Without/ With axillary lymph node metastasis with pathologic confirmation by needle biopsy With/ without received neoadjuvant chemotherapy prior to surgical resection  Exclusion Criteria:  Distant metastases The subject is known to be pregnant Pacemaker of another implantable device in the chest wall Allergy to dextran or other iron-containing particles