Inclusion Criteria:  female patients, >/=18 years of age; epithelial ovarian, fallopian tube or primary peritoneal cancer; platinum-resistant disease (disease progression within <6 months of platinum therapy) Eastern Cooperative Oncology Group（ECOG）performance status of 0-1  Exclusion Criteria:  non-epithelial tumours ovarian tumours with low malignant potential previous treatment with >2 chemotherapy regimens prior radiotherapy to the pelvis or abdomen within 5 years