Inclusion Criteria:  Women between 20-70 years Invasive unilateral breast carcinoma with histological confirmation History of invasive breast cancer TMN stage I-II according to AJCC 7th Histologically or radiologically no suspicion of distant metastases Performance status corresponding to ECOG grade 0-2 No psychological and geographical restriction in follow-up Written informed consent  Exclusion Criteria:  History of any cancer in the previous 5 years Bilateral breast cancer Male breast cancer Patients who are planning for surveillance in other institutions Unable to understand and fill out questionnaires