Inclusion Criteria:  Adults aged 18 years and over undergoing primary liver transplantation of a whole or partial liver graft from a cardiac or brain dead donor. Provision of written informed consent.  Exclusion Criteria:  Previous solid organ transplant. Acute liver failure. Fulminant hepatic failure. Patients receiving a living donor liver graft. Patients currently admitted to ICU prior to transplantation. Requirement of haemodialysis or CVVHF pre-operatively. Known allergy or adverse reaction to octreotide. Pre-operative decision to use intra-operative CVVHF. A positive pregnancy test.