Inclusion Criteria:  Inclusion Criteria :  Age> 18 years old Septic shock within 24 hours of admission in intensive care Stable dose of norepinephrine for at least 2 hours to maintain MAP> 65mmHg CRT index> 3 seconds despite the initial resuscitation (administration of antibiotics, filling of crystalloids of 20 mL / Kg, noradrenaline started) between H6 and H48 from admission in intensive care Non-opposition of the patient collected by the senior doctor in charge of the patient between H0 and H6 after admission if the patient is vigilant, otherwise a procedure of collecting non-opposition from relatives will be carried out with collection of the non-opposition of the patient once he is able to give it. Affiliation to a social security system (excluding AME)  Exclusion Criteria:  COVID19 patient (+) Pregnant and lactating woman Patient under Guardianship / Curatorship Refusal to participate CRT not evaluable (dark or damaged skin) Moribund patient Estimated life expectancy less than 1 month Participation in another interventional research involving the human person or period of exclusion at the end of a previous research involving the human person