Inclusion Criteria:  100 Cases were selected with type II (DM) patients who had been admitted for coronary angiography because of suspected (CAD) to the Catheter lab unit of Sohag University Hospital.  Exclusion Criteria:  Type 1 DM. Smoker. Hypertension. Pregnant women. Patient known non diabetic retinal disease non diabetic. nephropathy or neuropathy. History of familial dyslipidemia.