Inclusion Criteria:  Patients for whom the administration of intravenous corticosteroids was decided due to the diagnosis of new relapse Patients who were followed up with the diagnosis of RRMS Healthy controls  Exclusion Criteria:  Being younger than 18 years old Having any other neurological or metabolic diseases Ophthalmological diseases A history of optic neuritis and trigeminal symptoms Ocular trauma or surgery Contact lens use The patients who had a relapse attack 6 months prior to the study