Inclusion Criteria:  adult population (aged between18 years and 80 years) patients with suspected or new diagnosed or previously treated lymphatic system related diseases patients who had scheduled 68Ga-NEB PET/CT scan patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee  Exclusion Criteria:  patients with pregnancy the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.