Inclusion Criteria:  Diagnosis of grade I, II or III thumb CMC joint OA in their dominant hand according to the Eaton Classification Stage Pain rating of 4/10 on the Visual Analogue Scale (VAS) during activities of daily living (ADLs) at the time of the therapy initial evaluation. The ability to read and understand the patient information sheets and exercises. A minimum thumb abduction capacity of 40º.  Exclusion Criteria:  Previous hand and wrist surgeries, neurological disorders, diagnosis of OA that includes the wrist, rheumatoid arthritis, or any implication of an osteomyoarticular nature in the hand and / or wrist other than the CMC OA. Had received specific treatment for hand or thumb pain in the same limb in the last 6 months including an intra-articular joint injection to wrist, fingers, or thumb.