Inclusion Criteria:  Patients diagnosed with necrotizing pancreatitis according to the 2012 Atlanta classification criteria; Patients aged between 18 and 65 years; Patients who signed the informed consent;  Exclusion Criteria:  Patients without transmural stent placement; Patients with transmural plastic stent not metal stent placement before enrollment; Patients who underwent endoscopic transmural necrosectomy in other hospitals before admission; Patients complicated with chronic pancreatitis; Patients complicated with pancreatic tumor; Pregnant or lactating women.