Inclusion Criteria:  Patients aged 18 years old or more Histologically proven invasive breast cancer All patients diagnosed with breast cancer except T1N0 and Metastatic breast cancer Patients who completed their systemic neoadjuvant therapy  Exclusion Criteria:  Second malignancy Patients who started but didn't complete neoadjuvant systemic therapy Patients who didn't undergo surgery after neoadjuvant systemic therapy Pregnant patients