Inclusion Criteria:  Male, non-pregnant and non-lactating female subjects (20-65 years of age, inclusive). A clinical diagnosis of mild asthma with historical documentation of the asthma diagnosis according to either: (1) the National Asthma Education and Prevention Program (NAEPP) guidelines; (2) the Global Initiative for Asthma (GINA) Global Strategy for Asthma Management and Prevention. Stable mild asthma receiving one of the following required inhaled medication for at least 1 month prior to screening: (1) only short-acting beta-agonists (SABA) used as-needed; (2) low doses of ICS (as allowed in the ICS Table in Section 9.1.1, alone or in combination with SABA) used regularly with a stable regimen Forced Expiratory Volume in 1 second (FEV1) ≥ 80% of predicted after withholding SABA ≥ 8 hours. Airway responsiveness to methacholine demonstrated by a pre-albuterol-dose (baseline) PC20 ≤ 8 mg/mL. Nonsmoker for at least 6 months prior to the study and a maximum smoking history of 5 pack-years (the equivalent of one pack per day for 5 years). Provision of written informed consent. Other than asthma, in general good health. Body mass index (BMI) between 17 and 35 kg/m2 (inclusive). Able to correctly use MDI inhalers. Able to perform valid and reproducible pulmonary function tests including no evidence of spirometry effort-induced bronchoconstriction. If the subject or subject's partner is of child-bearing potential, a medically acceptable form of contraception will be used for the duration of the study. Medically acceptable contraceptives include: (1) surgical sterilization, (2) Health Authority approved female hormonal contraceptives, (3) an intrauterine device (IUD), (4) condoms with spermicide, or (5) diaphragm with spermicide.  Exclusion Criteria:  Evidence of conditions altering airway reactivity to methacholine, including upper or lower respiratory tract infections (e.g., pneumonia, viral bronchitis, allergic rhinitis, sinobronchitis, etc.) within 6 weeks before Screening. History of seasonal asthma exacerbations, in which case the subject should be studied outside of the relevant allergen season. History of cystic fibrosis, bronchiectasis, COPD, or other respiratory diseases including COPD, chronic bronchitis, emphysema, tuberculosis, pulmonary carcinoma, pulmonary fibrosis, pulmonary hypertension that, in the opinion of the Investigator, would compromise subject safety or interfere with the evaluations. History of cardiovascular, hematological, renal, neurologic, hepatic, psychiatric, endocrine dysfunction, including ECG with evidence of ischemic heart diseases and significant arrhythmias. Treatment in an emergency room or hospitalization for acute asthmatic symptoms within 3 months prior to screening. Known intolerance or hypersensitivity to any component of the albuterol MDI, beta2 receptor-agonist drug, HFA, any related compounds or methacholine. Need for daily oral corticosteroids within 3 months prior to screening. Cardiac arrhythmia or 12-lead electrocardiogram (ECG) abnormalities, that in the opinion of the Investigator would compromise subject safety or interfere with the evaluations, or a QTc > 440 ms for males and > 460 ms for females using Fredericia formula. Subjects receiving beta blocker via any route or who may require beta blockers during the study. History of narrow angle glaucoma, convulsive disorders, hyperthyroidism, uncontrolled diabetes, paradoxical bronchospasm History of malignancies History of alcohol or drug abuse Eye, brain, thoracic, and abdominal surgeries within 3 months prior to screening. Use of cromyolyn, leukotriene receptor antagonists (LTRA), nedocromil, zileuton, theophylline, or long-acting beta-agonists (LABA) within 1 month prior to screening. History of receiving muscarinic beta2-agonists (MABAs), short-acting muscarinic antagonists (SAMAs), long-acting muscarinic antagonists (LAMAs), anti-IgE, anti-IL5/5R, anti-IL4R, high dose ICS (as listed in the Inhaled Corticosteroid Table in Section 9.1.1), or systemic corticosteroid for treatment of asthma within 6 months prior to screening. Known Human Immunodeficiency Virus (HIV)-positive status. Participated in any interventional clinical trials within 1 month prior to screening. Pregnancy or breast feeding.