Inclusion Criteria:  Group 1 : Patients with bradykinin angioedema Patient with biologically proven hereditary angioedema with C1 inhibitor deficiency, Or a patient with bradykinin angioedema related to a plasminogen or factor XII mutation, Or patients with bradykinin angioedema related to ACE inhibitors or ARB2, Or patient with acquired bradykinin angioedema due to C1 inhibitor deficiency, Age > or = 18 years with the capacity to understand the requirements of the study and to give a non-opposition Having a blood collection scheduled as part of routine care Being insured by social security  Group 2 : Patients with histamine-mediated angioedema  Patient with idiopathic histamine angioedema as determined by the referring physician Age > or = 18 years with the capacity to understand the requirements of the study and to give a non-opposition Having a blood collection scheduled as part of routine care Being insured by social security  Exclusion Criteria:  Minors or protected adults, Pregnant or breastfeeding woman, Person deprived of liberty, Person in an emergency situation, Person having refused or unable to give their non-opposition