Inclusion Criteria:  • patients over 75 years old meet one of the following conditions. severe valvular heart disease as defined by echocardiography:  aortic stenosis, moderate or above, or valve area ≤1.0cm2, or maximal jet velocity ≥4.0m/sec, or mean pressure gradient ≥40mmHg, aortic regurgitation, moderate or above, or jet width ≥65% of left ventricular outflow tract, or regurgitant volume≥60ml/beat, or regurgitant fraction ≥50%,  Exclusion Criteria:  • Patients cannot be followed up for any reasons. •Patients have been enrolled in this study