Inclusion Criteria:  Women aged from 50 to 74 years who had smoked at least 25 pack years and quitted for less than 15 years Had given their consent and accepted the need for a 2-year follow-up Affiliated to the social security system  Exclusion Criteria  Presence of clinical symptoms suggesting malignancy (weight loss, hemoptysis) or ongoing infection (cough with fever) Evolving cancer History of lung cancer A 2-year follow-up not possible