Inclusion Criteria:  Male or female children and adolescents aged 6 to 17 years upon screening with a Diagnosis of Tourette Syndrome according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V). TTS ≥ 20 on the YGTSS at screening and baseline. In the Investigator's opinion the presenting tic symptoms caused impairment in the subject's normal daily routines. Females of childbearing potential had a negative pregnancy test, practiced acceptable double-barrier methods of contraception (or abstinence), and were not pregnant or lactating. Written informed assent or consent provided by the subject, and written informed consent provided by the parent(s)/guardians(s), as appropriate per the IRB/EC. In the opinion of the Investigator, the subject and designated guardian(s) and/or parent(s) must be considered likely to comply with the study protocol and to have a high probability of completing the study.  Exclusion Criteria:  Medical history consistent with another neurologic condition that may have had accompanying abnormal movements (e.g., Huntington's disease, Parkinson's disease, Sydenham's chorea, Wilson's disease, Mental retardation, Traumatic brain injury, Stroke, Restless legs syndrome) History of schizophrenia, bipolar disorder, or other psychotic disorder; Comorbid conditions such as: Obsessive Compulsive Disorder (OCD) and Attention Deficit Hyperactivity Disorder (ADHD) can be included. Active major depression disorder. History of neuroleptic malignant syndrome.  Subjects who have had treatment with:  investigational medication within 3 months of starting study depot antipsychotics within 3 months of starting study Antipsychotics with possible effects on TS symptoms: i.e., topiramate within 1 week; levodopa or dopamine agonists within 2 weeks prior to baseline. VMAT2 inhibitors within 2 weeks prior to baseline. Atypical antipsychotics within 4 weeks: this class include risperidone (Risperdal), quetiapine (Seroquel), olanzapine (Zyprexa), ziprasidone (Zeldox), paliperidone (Invega), aripiprazole (Abilify) and clozapine (Clozaril). Selective serotonin reuptake inhibitors unless the dosage has been stable for a minimum of 4 weeks prior to study start and not prescribed to relieve the neurological signs of TS. Sexually active males or females who would not commit to utilizing 2 of the approved birth control methods or who would not remain abstinent during the trial and for 90 days (males) or 30 days (females) following the last dose of investigational product. CBIT need to be started at least two months at screening. Could continue on existing therapy or stop it based on PI's opinion. Significant psychoactive substance use disorder within the past 3 months; or the urine drug screen was positive.  Significant lab abnormality:  Platelets ≤ 75,000/mm3 Hemoglobin ≤ 9 g/dl Neutrophils, absolute ≤ 1000/mm3 Aspartate transaminase (AST) > 3×ULN (upper limit of normal) Alanine aminotransferase (ALT) > 3×ULN Creatinine ≥ 2 mg/dl History or presence of any clinically important medical condition that, in the judgment of the investigator, is likely to deteriorate, could be detrimental to the subject, or could affect the subject's ability to complete the study.