Inclusion Criteria:  1.Aged between 35 and 75 years old 2.With a disease course between 2 weeks- 24weeks 3.Meeting the diagnostic criteria of ischemic stroke 4.Meeting the diagnostic criteria of phlegm and blood-stasis blocking collaterals pattern in T traditional Chinese medicine 5.Signed and dated written informed consent.  Exclusion Criteria:  1.Unstable vital signs, or serious heart, liver, lung, kidney and other organ diseases 2.Exclude Transient Ischemic Attack(TIA) 3.Patients who are participating in clinical trials of other drugs within the past 1 month 4.Pregnant or breastfeeding women