Inclusion Criteria:  ≥ 20-year-old Patients who had received radiotherapy (RT) or anthracycline-based CT or cancer immunotherapy or Targeted Therapy Diagnosis of Thoracic malignancy or breast cancer. Willing to sign the consent form of the subject and cooperate with the return visit Those who are admitted to the hospital and enter the general ward can receive the first ECG heart sound examination  Exclusion Criteria:  <20-year-old Can't received radiotherapy (RT) or anthracycline-based CT or cancer immunotherapy or Targeted Therapy Those who cannot perform the first examination after being admitted to the hospital and entering the general ward It is impossible to measure the group of ECG and heart sounds. For example, when using Pacemaker, the ECG showed ventricular tachycardia (VT) and Dextrocardia on admission. Patients who are bedridden and have difficulty in cooperating with return visits Any subject that the physician believes is at high risk for future uncooperative tracking Direct participants in this program