Inclusion Criteria:  Patients diagnosed with retinopathy of prematurity through clinical fundus screening; According to the international ROP classification, at least one eye of the patients at the initial stage of treatment is stage 1+, stage 2+, stage 3, stage 3+ in zone 1 or stage 2+, stage 3+ in zone 2 or AP-ROP ； Patients receiving laser therapy, intravitreal injection of Conbercept or Ranibizumab;  Exclusion Criteria:  Patients with neurological diseases that seriously affect visual function; Patients or their mothers (during pregnancy) have received intravitreal or systemic anti-VEGF drug treatment for other diseases;