Inclusion Criteria (must satisfy all of the following selection criteria) :  Those who are 70 years of age or older as of the date of consent Established arteriosclerotic cardiovascular disease (coronary artery disease, cerebrovascular disease, or peripheral vascular disease) Subjects who have consented to the study plan and follow-up observation by the patient or representative, and who consented in advance in writing to the clinical subject consent approved by the research deliberation committee/ethics committee of the research institution  Exclusion Criteria:  Take statins or ezetimibe within the last 4 weeks In case of end-stage kidney disease (eGFR<30 ml/min/1.73m2) Heart surgery or major surgery is planned within the next 6 months Patients with chronic diseases such as severe lung disease, stroke, etc. Patients with chronic inflammatory diseases who require oral, intravenous, or intra-articular steroid treatment (Ointments, inhalants, or intranasal steroids are allowed) If you have been diagnosed with cancer within the past 1 year or are currently receiving chemotherapy In the case of clinically significant abnormal findings that may infringe on the safety of the study by the investigator's judgment confirmed in a screening visit, physical examination, blood test, or electrocardiogram Liver disease, bile duct obstruction, or liver enzyme level (ALT/AST) is more than 3 times normal If you have a disease whose life expectancy is less than 1 year If you do not want or cannot comply with the procedure described in the research proposal