Inclusion Criteria:  Children aged at least 3 years old or adult with Noonan syndrome Patients affiliated to or beneficiaries of a social security scheme Patients able to receive information on the progress of the study and understand the information form to participate in the study. That implies to master the French language and not to be subject to a restriction of rights by the judicial authorities Patients or legal representative who have given their consent to participate in the study (expression of no objection)  Exclusion Criteria:  Patients subject to a legal protection measure (guardianship, curators, or safeguard of justice) Pregnant or breastfeeding women