Inclusion Criteria:  Clinical diagnosis of Type 2 Diabetes Taking oral-antidiabetic medication  Exclusion Criteria:  Smokers, Alcohol drinkers, Inflammatory bowel or autoimmune disease, Immunodeficiency, Using anti-epileptic, incretin enhancer (DPP-4 inhibitor), insulin or insulin analogs, dietary supplements Systemic antibiotics within 6 weeks before inclusion Use of probiotics within 3 months before inclusion Breast-feeding or pregnancy