Inclusion Criteria:  A diagnosis of diabetes mellitus; Understanding of study and provision of written informed consent; and 22 years of age or older.  Exclusion Criteria:  Persistent visual impairment in one or both eyes; History of retinal vascular (vein or artery) occlusion; History of ocular injections, laser treatment of the retina, or intraocular surgery other than cataract surgery without complications; Subject is contraindicated for fundus photography (for example, has light sensitivity); Subject has contraindications for mydriatic medications or is unwilling or unable to dilate; Subject is currently enrolled in an interventional study of an investigational device or drug; or Subject has a condition or is in a situation which in the opinion of the Investigator, might confound study results, may interfere significantly with the subject's participation in the study, or may result in ungradable dilated fundus photographs.