Inclusion Criteria:  American Society of Anesthesiologists (ASA) physical status ≤ II Age from 21 to 50 years  Exclusion Criteria:  ASA physical status > II Age < 21 years or > 50 years Pregnant women Breastfeeding Bronchial asthma Chronic obstructive pulmonary disease Diabetes Mellitus Hypertension Ischemic heart disease Rheumatic heart disease Heart failure Heart block Sick sinus syndrome Sinus bradycardia Chronic hypotension Anemia (Hb < 10 g/dl) Renal or hepatic dysfunction Central nervous system disease Allergic fungal sinusitis Patients on beta-blockers Alcohol or drug abuse Anticoagulation therapy, Bleeding diathesis Agents influencing autonomic nervous system Allergy to the study drugs Any contraindication of oral intake