Inclusion Criteria:  Undergoing coronary angiography or coronary computer tomography angiography Written informed consent  Exclusion Criteria:  Prior percutaneous coronary intervention (PCI) Prior coronary artery bypass graft (CABG) Screening coronary artery disease before treating other heart diseases Without blood biochemistry outcome With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up) Other situations which make patients fail to be photographed