Inclusion Criteria:  Patient is dispositioned to receive definitive or adjuvant radiotherapy for treatment of a diagnosed head and neck malignancy. Treating radiation oncologist has determined the necessity of an oral stent and a device has been fabricated by dentistry at MD Anderson Cancer Center (MDACC). Patient has received pre-treatment imaging which includes the mandibular and maxillary dentition. Eastern Cooperative Oncology Group performance status (ECOG PS) 0-2. Signed study-specific consent form.  Exclusion Criteria:  No pre-treatment computed tomography (CT) imaging including the maxilla and mandible is available. Prior head and neck radiotherapy. Severe trismus with an incisal opening of < 10 mm. Inability to comply with the study procedures. Patients who have received dental stents fabricated outside of MDACC.