Inclusion Criteria:  Age >18 years old at the time of study entry Currently receiving standard of care systemic anti- cancer therapy (chemotherapy, immunotherapy, endocrine and targeted therapy) for solid organ malignancy and has received at least one cycle. Scheduled to be undergoing routine venous laboratory blood tests as part of standard of care Can provide written informed consent Blood samples collected and stored in K2-EDTA vacutainers only  Exclusion Criteria:  Known inherited or acquired bleeding disorder History of haematological malignancy Known poorly controlled anti-coagulation Inadequate use and understanding of the English language, requiring a translator