Inclusion Criteria:  Male or female aged ≥18 years at the time of signing the informed consent Chronic kidney disease with eGFR <45 mL/min/1.73 m2 and UACR >300 mg/g creatinine (eGFR=estimated glomerular filtration rate; UACR=Urine Albumin-to-Creatinine Ratio) Patient is willing to comply with the study requirements for therapy during the entire study period Patient is capable of providing written informed consent to participate in the study  Exclusion Criteria:  Patients with underlying renal disease likely to receive disease-specific therapy other than SoC (Standard of Care) Patient expected to require renal replacement therapy within less than one year from study inclusion