Inclusion Criteria:  Women aged 19 to 40 years old A person diagnosed with breast cancer by biopsy Those who don't have evidence of distant metastasis Eastern Cooperative Oncology Group(ECOG) performance status: 0-2 score Before registering for clinical trials, chemotherapy, radiation therapy, anti-hormone therapy, immunotherapy, and surgery are not performed A person who has fully understood and listened to the explanation of this clinical trial and then gave written consent  Exclusion Criteria:  Histologically, a person diagnosed with follicular or sarcoma Those with a history of breast cancer (including recurrent breast cancer) A person diagnosed with another cancer before breast cancer A person diagnosed with metastatic breast cancer A person who has a mental illness and has a hard time understanding clinical trials Those who plan to conduct follow-up observation elsewhere(to change of hometowm) Menopausal factors without menstruation after more than a year from the last menstrual date A pregnant woman Inappropriate for participation in clinical trials