Inclusion Criteria:  Men and women both aged between 18-35 years Presenting minimum 5 acne lesions (whiteheads, blackheads, papules, pustules, nodules) Study subject who will be agreed with Online informed consent.  Exclusion Criteria:  Have infected acne lesions If study subject suffers from any serious medical conditions such as uncontrolled hypertension, diabetes mellitus, past or current malignancy, liver or kidney dysfunction, active pulmonary tuberculosis other severe dermatitis, or any infectious or systemic diseases. Use of a topical medication containing steroids for the treatment of skin disease more than once per month. Hypersensitive skin. Erythema, or telangiectasia at the test site. Use of the same or similar cosmetics (or pharmaceutical) on the test site within three months of screening. Having undergone a skin peeling or having wrinkles removed within six months. Any other reasons of unsuitability for the clinical trial at the discretion of the study.