Inclusion Criteria:  Pregnant women who wish to sustain their pregnancy Women who have tested positive (blood or urine) for pregnancy in the first trimester treated with progestogens or any alternative treatment for early bleeding in pregnancy with evidence of an intrauterine pregnancy / unexplained recurrent OR pregnancy loss (with ≥ 2 previous pregnancy losses) with evidence of an intrauterine pregnancy OR having undergone IVF/ ART embryo transfer and taking progestogen for luteal phase support (LPS), with evidence of an intrauterine pregnancy Signed informed consent, allowing consent to contact all treating, or diagnosing HCP Able and willing to read and comprehend written instructions; comprehend and complete the questionnaires required by the protocol  Exclusion Criteria:  Serious disease or disease requiring teratogenic treatment (e.g., Lupus Erythematosus, Multiple Sclerosis, cancer) Multifetal pregnancy More than four (4) previous IVF embryo transfers Previous exposure to dydrogesterone in index pregnancy Documented substance abuse Treatment with hormones which are known to cause malformations Participation in an observational study that might, in the recruiting HCP's opinion, influence the assessment for the current study Participation in a randomized clinical trial in the last 3 months Previous enrollment in the PEARLY study