Inclusion Criteria:  Age > 18 and < 81 years Stable angina at least 1 vessel disease in either the left coronary artery or right coronary artery Stenosis grater than 50% and no stenosis greater than 40% on contralateral vessel unless fractional flow reserve by CT (FFRct) >0.80 Vessel segment > 2 mm in diameter Subject eligible for Dual Anti Platelet Therapy (DAPT  Exclusion Criteria:  Significant bleeding risk or other contraindications against heparinization or DAPT Known pregnancy Life expectancy < 120 days Patient unable to provide informed consent Patients with CTO (Chronic Total Occlusion).