Inclusion Criteria:  For inclusion in the study, participants must meet the following criteria:  chronic wounds of any origin or wound phase, including locally infected chronic ulcers wound size up to 20x10 cm wounds without visible tendon or bone participant age between 18 95 years  Exclusion Criteria:  • acute wounds  in case of multiple wounds, only one wound will be assigned as study wound wounds with > 30 percentage necrotic eschar pregnant or breastfeeding women or women of childbearing age participants with intake of antibiotics within one week before the start of the enrollment allergy or intolerance against a primary or secondary dressing allergy or intolerance against cold plasma participation in any other clinical trial up to one month prior to study enrollment