Inclusion Criteria:  Daytime mean SBP ≥135 mmHg and ≤160 mmHg by ABPM, without antihypertensive medication  Exclusion Criteria:  Secondary hypertension, orthostatic hypotension Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) >2× upper limit of normal (ULN) Elevated potassium >5 mEq/L Estimated glomerular filtration rate (eGFR) of ≤30 mL/min/1.73m^2 Received an investigational agent within the last 30 days Type 1 diabetes mellitus, poorly controlled Type 2 diabetes mellitus, newly diagnosed Type 2 diabetes mellitus History of any cardiovascular event within 6 months prior to randomization History of intolerance to SC injection(s)