Inclusion Criteria:  Patients scheduled to undergo 1 to 2 level laminectomy Between the ages of 18-85  Exclusion Criteria:  Minimally invasive surgery Prior daily opioid usage within 6 months. Use of concomitant procedures such as spinal fusion, revision procedure at the same level. History of a chronic pain syndrome, uncontrolled diabetes defined as A1C > 6.5, immunocompromised condition such as active cancer treatment, history of transplant, benign prostatic hyperplasia or history of urinary retention, and other conditions which require chronic steroid therapy or immunosuppressants. Non-English speakers Patients allergic to Depo-Medrol and/or glucocorticoids, or other steroids