Inclusion Criteria:  Male or female subjects aged 18-80 years  For the group of hypercholesterolemic patients :  LDL-cholesterol level >1.9 g/L with or without treatment to make the diagnosis of hypercholesterolemia (laboratory test less than 12 months old at inclusion)  For the healthy group :  ● No cholesterol-modifying therapy.  Subject not having hypercholesterolemia (biological assessment less than 12 months old at inclusion with LDL-cholesterol level < 1.9 g/L) and not taking cholesterol-lowering treatment. Subjects who are affiliated or beneficiaries of a social security plan Subject agreeing to participate in the study and having signed an informed consent  Exclusion Criteria:  Protected person, as defined by articles L1121-5, L1121-6 and L1121-8 of the Public Health Code: pregnant or breastfeeding woman, person deprived of liberty by judicial decision, adult person unable to give consent. Person who does not understand the French language