Inclusion Criteria:  Female patients ages 8 - 39 years of age  Seen in CHCO or AMC outpatient clinics for any of the following reasons:  At risk for fertility problems (Z91.89) Encounter for fertility preservation counseling (Z31.62) Primary ovarian insufficiency Premature ovarian failure/premature menopause Diminished ovarian reserve At least 12 months post-completion of chemotherapy and/or radiation  History of a fertility-threatening diagnosis receiving chemotherapy; radiation; or surgery to the reproductive organs for malignancy, including but not limited to:  Any type of cancer/malignancy Rheumatoid arthritis Systemic lupus erythematosus Aplastic anemia Fanconi anemia Diamond-Blackfan syndrome Hurler syndrome Other autoimmune conditions  Exclusion Criteria:  Disorders of sexual development (i.e., gonadal dysgenesis, Turner syndrome/mosaicism, etc.) History of bilateral oophorectomy Transgender patients not receiving chemotherapy; radiation; or surgery to the reproductive organs for malignancy Inability to consent/assent