Inclusion Criteria:  Syncope according to the American College of Cardiology Guidelines 2017 At least 2 vasovagal syncope spells in the preceding 12 months At least -2 on the Syncope Symptom Score for Structurally Normal Hearts At least 18 years old with informed consent  Exclusion Criteria:  Other cause of syncope A 5-minute stand test resulting in the diagnosis Orthostatic Hypotension or Postural Orthostatic Tachycardia Syndrome An inability to give informed consent Pregnant Unwilling or unable to use adequate birth control while on study drug. An important valvular, coronary, myocardial, or conduction abnormality, or significant arrhythmia Uncontrolled hypertension Uncontrolled hyperthyroidism A permanent pacemaker Taking or has recently taken a monoamine oxidase inhibitor Pheochromocytoma Glaucoma Prior use of atomoxetine for syncope Clinical need for atomoxetine or another potent norepinephrine transporter inhibitors (Ki NET < Ki SERT, Ki NET > 10 Ki atomoxetine), Current use of β-blocker, bupropion, α1-adrenergic agonists or antagonists, tricyclic antidepressants, serotonin reuptake inhibitors, scopolamine, theophylline, or fludrocortisone.