Inclusion Criteria:  Patient written consent is given A de novo lesion Mild to moderate burden of calcifications detected on two orthogonal views using normal radiation power  Exclusion Criteria:  Exclusion criteria patient-related:  Patient <18 years old Pregnant female Contraindication to dual antiplatelet therapy Thrombocytopenia <100 000 Major surgical intervention planned  Exclusion criteria lesion-related:  Significant left main lesion Bifurcating lesion with a significant side branch to be treated Lesion length > 25 mm Chronic total occlusion Lesion with heavy calcifications where a rotational atherectomy or lithotripsy should be planned Lesion in a graft In-stent restenosis lesion Lesion responsible of a STEMI