Inclusion Criteria for Cancer Arm Participants:  Age 18 years or older Able to provide a written informed consent Confirmed diagnosis or highly suspicious cases of gynecologic malignancies No prior or ongoing anti-cancer therapy (local or systematic) prior to study blood draw  Exclusion Criteria for Cancer Arm Participants:  Pregnancy or lactating women Recipients of organ transplant or prior non-autologous (allogeneic) bone marrow transplant or stem cell transplant Recipients of blood transfusion within 7 days prior to study blood draw Recipients of any anti-cancer therapy within 30 days prior to study blood draw, due to diseases other than cancer  Inclusion Criteria for Benign Arm Participants:  Age 18 years or older Able to provide a written informed consent Confirmed diagnosis of benign gynecologic diseases No prior radical treatment of the benign diseases prior to study blood draw  Exclusion Criteria for Benign Arm Participants:  Pregnancy or lactating women Recipients of organ transplant or prior non-autologous (allogeneic) bone marrow transplant or stem cell transplant Recipients of blood transfusion within 7 days prior to study blood draw Recipients of any anti-cancer therapy within 30 days prior to study blood draw, due to diseases other than cancer