Inclusion Criteria:  Ischemic stroke diagnosed by MRI Age over 20 years old No worsening of stroke or second stroke this time  Exclusion Criteria:  Unable to understand instructions normally, or communication difficulties Patients with endotracheal tube or tracheostomy Angina in recent 3 months, myocardial infarction, heart failure Patients with asthma or chronic obstructive pulmonary disease, spontaneous pneumothorax, and ongoing pneumonia Patients with untreated hernias Pregnant Ongoing fever (body temperature>38.5°C) Poor hypertension control (higher than 170/100 mmHg three days before intervention) Patients who have had cerebral hemorrhage or aneurysm