Inclusion Criteria:  Male: 50-70 years old Subject is willing and able to comply with the study protocols. Subject is willing to participate in all study procedures BMI 18.5 - 40 kg/m2 Weight ≥ 110 pounds Prescription medication if on a 6-month self-reported stable dose Regularly consume alcoholic beverages (2 drinks/week to 2 drinks/day) Non-smokers  One standard drink of alcoholic beverages is defined as follow:  12-ounces of beer (5% alcohol content) (~1 regular bottle). 8-ounces of malt liquor (7% alcohol content) (~1 regular bottle). 5-ounces of wine (12% alcohol content) (~½ glass) 1.5-ounces of 80-proof (40% alcohol content) distilled spirits or liquor (e.g., gin, rum, vodka, whiskey) (~ 1 shot)  Exclusion Criteria:  BMI ≥ 40 kg/m2 Daily use of aspirin or NSAIDs Dislike or allergic to any food, especially wine, grape, and alcohol Vegan, Vegetarians, food faddists, or those consuming a non-traditional diet Alcohol consumption < 2 drinks/week (i.e. 1 bottle of beer, ½ glass of wine, and 1 shot of hard liquor) Alcohol consumption > 2 drinks/ day Fruit consumption ≥ 2 cups/day Vegetable consumption ≥ 3 cups/day Fatty Fish ≥ 3 times/week Coffee/tea ≥ 3 cups/day Dark chocolate ≥ 3 oz/day Self-reported restriction of physical activity due to a chronic health condition Self-reported chronic/routine high intensity exercise Self-reported diabetes Blood pressure ≥ 140/90 mm Hg Self-reported renal or liver disease Self-reported heart disease, which includes cardiovascular events and Stroke Self-reported Cushing's syndrome Self-reported chronic/routine high-intensity exercise Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT Abnormal Liver or Chemistry panels (laboratory values outside the reference range) if determined to be clinically significant by the study physician. Self-reported cancer within the past 5 years Self-reported malabsorption Use of multi-vitamin and minerals other than a general formula of vitamins and minerals that meet the recommended dietary allowance (RDA) Not willing to stop any supplement use, including herbal, plant or botanical, fish oil, oil supplements a month prior to study enrollment. Indications of substance or alcohol abuse within the last 3 years Current enrollee in a clinical research study. Reactive hyperemia index (RHI) value ≥ 2.8 (measured by PAT at the first study visit) Raynaud's disease, history of bleeding disorder and/or abnormal bleeding, and history of gastrointestinal ulceration and/or bleeding Under current medical supervision 1 ug/ml and 3 ug/ml collagen screening maximal platelet aggregatory response of < 65%. Platelet number or mean platelet values that are outside of the normal reference range as indicated on a complete blood cell count report from the University of California Davis Medical Center Current diagnosis of anemia; or a screening hemoglobin and hematocrit that is less than the normal reference range.Individuals with blood clotting or platelet defect disorders  The following special populations will be excluded:  Individuals who are not yet adults (infants, children, teenagers) Pregnant women Prisoners