Inclusion Criteria:  The severity of atopic dermatitis according to the EASI index (Eczema Area and Severity Index, index of prevalence and severity of eczema)> 7 points (moderate and / or severe course of atopic dermatitis); A burdened family allergic history (at least one of the parents has atopic dermatitis, food allergy, bronchial asthma and / or allergic rhinitis); The presence of sensitization in the child to one or more of the studied food and household allergens, determined at the screening stage by the ImmunoCAP method: cow's milk protein, chicken egg protein, wheat, soy, hx2 "house dust mixture: Dermatophagoides pteronyssinus, D. farinae, Blatella germanica ".  Exclusion Criteria:  Use of topical calcineurin inhibitors (pimecrolimus) in the last 30 days prior to inclusion in the study; A history of concomitant severe neurological, endocrinological, cardiovascular, hepatic and renal diseases; The presence of acute bacterial, viral infections; The child's lack of sensitization to detectable food and household allergens; Clinically significant changes in the general analysis of urine, general analysis of blood, biochemical analysis of blood; Refusal to sign an informed consent to participate in the study; Inability to observe the patient during the study.