Inclusion Criteria:  Appropriately signed and dated informed consent Age ≥18 at time of consent Patient candidate for renal denervation with the Paradise System based on physician's assessment OR Patient treated with the Paradise Ultrasound Renal Denervation System within the 6 months prior to consent  Exclusion Criteria:  Patients who meet any of the contraindications listed in the Instructions for Use will be excluded.  The contraindications are:  Stented renal artery Less than 18 years of age Pregnant Known allergy to contrast medium Renal arteries diameter < 3 mm and > 8 mm Renal artery with Fibromuscular (FMD) disease Renal artery aneurysm Renal artery stenosis of any origin >30% Iliac/femoral artery stenosis precluding insertion of the Paradise catheter