Inclusion Criteria:  Women aged 18 to 36 with diagnosis of PCOS and insulin resistance or glucose intolerance.  Exclusion Criteria:  Previous use of any hormonal treatment in the past three months; Other causes of anovulation; Gynecological or other associated conditions (endometriosis, adenomyosis or diabetes mellitus); FSH (Follicle Stimulating Hormone) > 15 Ul / L (2nd to 5th day of the cycle); Beta-hcG (human chorionic gonadotropin) positive (pregnancy).