Inclusion Criteria:  The elderly patients(≥ 60) with AML diagnosed according to WHO criteria; Participants are ineligible for induction regimen; The Eastern Cooperative Oncology Group (ECOG) performance status is 0-3; The patients and their families agree and sign the informed consent form.  Exclusion Criteria:  Previous treatment for AML (including hypomethylating agents and other chemotherapy drugs); Infiltration of the central nervous system; Drugs use history affecting CYP3A within 7 days before enrollment; participants considered by the investigator to be unsuitable for inclusion.