Inclusion Criteria:  Diagnosis of open-angle glaucoma (OAG) (including pigmentary, pseudoexfoliative or refractory glaucoma) or ocular hypertension (OHT).  For OAG:  Glaucomatous visual field defects or optic nerve defects and defined as one or more of the following:  A cluster of 3 or more points in an expected location of the visual field depressed below the 5% level, at least 1 of which is depressed below the 1% level on the pattern deviation (PD) plot; or Glaucoma hemi-field test "outside normal limits" Note: Visual field reliability indices (i.e., fixation losses, false positives, and false negatives) should all be less than 33%. For subjects with a screening visual acuity of 20/100 or worse, a visual field is not required, and the above criteria do not need to be met.  OR  Nerve abnormality characteristic of glaucoma as evaluated by clinical ophthalmoscopy defined as one or more of the following:  Diffuse thinning, focal narrowing or notching of the optic disc rim especially at inferior or superior poles. Localized abnormalities of the peripapillary retinal nerve fiber layer, especially at inferior or superior poles. Optic disc neural rim asymmetry of the two eyes consistent with loss of neural tissue.  For OHT: Diagnosis based on the investigator's evaluation.  Subject eye is phakic or pseudophakic:  If phakic, then the crystalline lens will not have visually significant cataract that is expected to require cataract surgery within next one year. Cataract will be evaluated by the clinician subjectively. If pseudophakic, then a posterior chamber IOL in the capsular bag is present. A minimum of 60 days is required between cataract surgery and study screening. Anterior chamber intraocular lens (IOL), iris fixed IOL, or implantable contact lens (ICL) will be excluded. Mean IOP with medication at screening between 12 mmHg and 26 mmHg, inclusive, on up to 4 ocular hypotensive medications with stable regimen for 2 months before screening OR an IOP of 22 to 36 mmHg on 0 (zero) ocular hypotensive medications. At baseline, unmedicated IOP of 20 to 36 mmHg for OAG subjects who are washed-out; 22 to 36 mmHg for OHT subjects on no medications. Note: For subjects with refractory glaucoma (prior failed incisional or cilioablative glaucoma surgeries or uncontrolled IOP with maximum tolerated ocular hypotensive medications), washout is not required.  Iridocorneal angle anatomy defined as follows:  Trabecular meshwork visible on gonioscopy defined by Shaffer grade ≥ 3. Normal anatomy as determined by gonioscopy. Corrected visual acuity of 20/200 or better in the study eye. The non-study eye must have hand motion or better vision. Age 35 years or older If the subject is using anticoagulants, the subject is willing and able to temporarily discontinue using anticoagulant medications 3 days prior to laser procedure. Subject will resume anticoagulant medications post-procedure. Available, willing, with sufficient cognitive awareness to comply with examination procedures and schedules. Signed written informed consent.  Exclusion Criteria  Previous glaucoma surgeries including stent implantation or other laser surgeries on study eye. Note: in case of refractory glaucoma subjects, prior failed incisional or cilioablative surgeries for glaucoma are acceptable. Prior intraocular surgery except cataract surgery per inclusion criteria #3. Pseudophakic eyes with an anterior chamber intraocular lens (IOL), iris fixed IOL, or implantable contact lens (ICL). Cup: Disc (C:D) ratio ≥ 0.8.  Glaucoma types as follows:  Traumatic, uveitic, neovascular, or angle-closure. Glaucoma associated with vascular disorders.  Corneal status as follows:  Any condition that would preclude safe participation in the study or reliable IOP assessments including active inflammation, edema, keratitis, keratoconjunctivitis, keratouveitis. Clinically significant dystrophy such as bullous keratopathy or Fuch's dystrophy. Guttata that would preclude safe participation in the study or reliable study assessments. Anticipated surgery of any type (including LASIK, LASEK, PRK, cataract, etc.) during the study that may alter IOP measurement. Corneal opacities or disorders that would inhibit visualization of the angle (such as severe arcus senilis). Central corneal thickness less than 440 microns or greater than 620 microns.  Choroid status as follows:  Choroidal detachment Effusion Choroiditis Neovascularization Any active choroidopathy.  Retinal or optic nerve disorders, either degenerative or evolutive, that are not associated with the existing glaucoma condition including: proliferative diabetic retinopathy, central retinal artery occlusion, central retinal vein occlusion, wet age-related macular degeneration, dry age-related macular degeneration (e. g., presence of numerous large drusen associated with disturbance to or elevation of the retinal pigment epithelium), significant retinal pigment epithelial changes or optic atrophy, pathological myopia, red disease.  Note: Minor diabetic retinopathy or hypertensive retinopathy are permitted.  Elevated episcleral venous pressure associated with:  Active thyroid orbitopathy. Cavernous sinus fistula. Sturge-Weber syndrome. Orbital tumors. Orbital congestive disease.  Other ocular conditions as follows:  Sequelae from trauma that would preclude safe participation in the study or reliable study assessments (e.g., chemical burns, blunt trauma, etc.) Chronic ocular inflammatory disease or presence of active ocular inflammation or infection (e.g., uveitis, iritis, iridocyclitis, retinitis) Any pathology for which, in the investigator's judgement, the following would be either at risk or contraindicated:  i. Compliance to elements of the study protocol (e.g., ophthalmic examinations, follow- up visits) ii. Subjects with inadequate space in the anterior chamber and/or angle as determined by slit lamp examination and gonioscopy.  Subject status as follows:  Uncontrolled systemic disease (e.g., diabetes, hypertension) that could compromise their participation in the study. Use of systemic medications (either current, within 30 calendar days of screening exam, or anticipated) that may cause an increase in IOP, (e.g., systemic steroids including oral or IV formulation, topical steroids applied on the periorbital surface within ¼" of the external lid margins and oral inhaled steroids). Nasal inhaled steroids are allowed. Active concurrent enrollment in any investigational trial or previous participation in any investigational trial within 30 days of the screening exam. Women who are nursing, are pregnant or are of childbearing potential who refuse to use reliable contraception.