Inclusion Criteria:  Patients ≥ 18 years; Have been diagnosed positive of SARS-CoV-2 in the Virological Laboratory of Ambroise Paré hospital; Have been blood sampled between 1 day and 14 days from the first clinical syndromes, and their collections of serum or plasma are conserved and accessible; Affiliated to the social security scheme or entitled; Informed and non-opposed to participating to the study.  Exclusion Criteria:  Opposition of patient to participation to the study; Foreign patients under french AME scheme.