Inclusion criteria  Female and male individuals, with clinical diagnosis of DM2 for at least 6 months; Age over 30 years; BMC equal to or above 18.5 kg/m2, without weight change in the last 3 months; HbA1c between 7.5% and 10.5%.  Exclusion criteria  Use of herbal supplements, antioxidants, and multivitamins in the last 3 months; Pregnancy or lactation; Chronic renal failure with glomerular filtration rate calculated by MDRD < 30 mL/h; Myocardial infarction in the last than 6 months Current neoplasia; Chronic use of glucocorticoids; Bariatric surgery.