Inclusion Criteria:  Age < 40, will undergo IVF-ET; Low ovarian reserve: Antral follicle count (AFC)<7, or AMH<1.1ng/ml; or has a history of poor ovarian response: in the last hyper stimulation cycle, the number of retrieved oocytes<3; Spouse' semen examination is normal, or after semen prewash can reach the standard of common IVF or Intracytoplasmic Sperm Injection(ICSI).  Exclusion Criteria:  Male with azoospermia; Male/female's chromosome is abnormal; Adenomyosis, uterine fibroids, endometrial polyps, scar uterine, reproductive system tuberculosis, oviduct effusion, pelvic lesions such as ovarian endometriosis cyst or tumor; Female has other endocrine disease: thyroid diseases, hyperprolactinemia, insulin resistance, diabetes, adrenal diseases, etc. Definitively diagnosed autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, antiphospholipid syndrome; Other pathogenesis that leads to recurrent miscarriage or agnogenic recurrent miscarriage; A history of cancer and has received radiotherapy and chemotherapy; Had acupuncture treatment in recent 3 months; Unwilling to sign the informed consent of this study.