Inclusion Criteria:  Participants must sign the form of informed consent and agree to follow the protocol requirements Women willing to participate in the study must protect against possible pregnancy during all the study long Age 18-50 years Pulmonary tuberculosis HIV/AIDS Indication for in-patient standard antituberculosis treatment  Exclusion Criteria:  Investigational research agents received within 30 days before the screening and participation in other clinical trials Immunosuppressive medications received within 6 months before the screening Current drug abuse for more than 3 years Contraindications to interferons of standard antimicrobial therapy