Inclusion Criteria:  Those who are at least 20 years old (inclusive) and are willing to sign a written informed consent after explaining the purpose of the research. A patient with irritable bowel syndrome diagnosed by a doctor for at least 6 months (inclusive). Communicate in Mandarin or Hokkien.  Exclusion Criteria:  Those who cannot take care of themselves in daily life. Those who have had severe abdominal and colorectal surgery. Those who have been diagnosed with inflammatory bowel disease or colorectal cancer. Those with a history of mental illness, such as schizophrenia and obsessive- compulsive disorder. Women who are pregnant, breastfeeding, and less than 12 months after delivery. Other serious diseases, such as acute myocardial infarction, endocrine disease, decompensated cirrhosis, stroke, and end-stage renal disease, etc.