Inclusion Criteria:  Diagnosed as liver cancer, hepatolithiasis, benign liver tumor, with clear indications for liver resection; Liver function Child A-B; There is no contraindication to surgery for cardiopulmonary function; The expected remaining liver volume/standard liver volume is less than 50%;  Exclusion Criteria:  In the late stage of the disease, patients with frequent symptoms such as cerebral edema accompanied by cerebral herniation and clinical evidence indicating intracranial hemorrhage; PaO2/FiO2 is less than 200 and cannot be corrected; Patients with diffuse intravascular coagulation; Those with active bleeding; Uncontrolled infection; The platelet count is less than 50,000/μL and cannot be corrected; There is no blood vessel available for dialysis treatment; HIV, HDV or HCV positive; Drug abuse within 1 year; Those with severe systemic circulatory failure; Those who are highly allergic to the drugs used in the treatment process, such as plasma, heparin, protamine, etc.; Combined pregnancy; Patients with hepatorenal syndrome; Patients with autoimmune liver disease; Patients with non-alcoholic fatty liver and hereditary liver diseases (Wilson syndrome and a-antitrypsin deficiency); Other conditions that the clinician believes cannot tolerate the treatment.