Inclusion Criteria:  Age > 21 years Voluntarily signed an informed consent form BMI ≤ 35 kg/m2 Women of child-bearing potential are required to use birth control measures during the whole duration of the study. Willingness to abstain from partaking in any treatments other than the study procedure Willingness to comply with study instructions, to return to the clinic for the required visits and to undergo punch biopsies in the abdominal area.  Exclusion Criteria:  Electronic implants (such as cardiac pacemakers, defibrillators, and neurostimulators) Metal implants in the treated area Drug pumps Malignant tumor Pulmonary insufficiency Injured or otherwise impaired muscles in the treated area Cardiovascular diseases Disturbance of temperature or pain perception Hemorrhagic conditions Septic conditions and empyema Acute inflammations in the treated area Systemic or local infection such as osteomyelitis and tuberculosis Contagious skin disease Elevated body temperature Application during pregnancy, postpartum period, nursing, and menstruation Graves' disease Skin related autoimmune diseases that may contradict the biopsy Poor healing and unhealed wounds in the treatment area Any disease or condition contradicting the skin tissue biopsy Any disease or condition that may compromise the histologic observation at the pathologist discretion