Inclusion Criteria:  Patients undergoing simple CABG (on-pump/off-pump) for the first time. Patients who signed the informed consent form and willing to undergo cardiac denervation.  Exclusion Criteria:  Age > 75； Emergent CABG; Cardiac surgery history； EF < 40%； Moderate or severer mitral valve regurgitation; Receiving other cardiac surgery except of CABG at the same time； Requiring mechanical or pharmacological therapy for hemodynamic support before CABG, such as ECMO or IABP; History of AF last 6 months; Taking antiarrhythmic agents except of beta-blockers last 2 weeks; Untreated hypothyroidism； Serum creatinine > 150 umol/L.