Inclusion Criteria:  Diagnosed with head and neck squamous cell carcinoma of the mucosa Receiving treatment at Thomas Jefferson University - Center City by a fellowship-trained HNC surgeon Age > 18 Provide signed written informed consent document  Exclusion Criteria:  Impaired judgement or those unable to provide informed consent Anything that would place the patient at increased risk or preclude the individual's full compliance with or completion of the study Enrollment in other clinical trial