Inclusion Criteria:  Body mass index range = 30.0 to 40.0 kg/m2 Being sedentary (<1 h regular physical activity/wk) Medication stable for 3 mo. Current use of physician confirmed diabetes medication, fasting glucose values ≥ 126 mg/dL and 2 hr oral glucose tolerance test (OGTT) values ≥ 200 mg/dL will be used as the criteria for type 2 diabetes  Exclusion Criteria:  Type 1 diabetes, [insulin use] Major depressive disorder Severe neuropathy Current tobacco use (must have quit for 1 yr or more if a previous user) Renal, liver, peripheral artery, or carotid artery disease Current cancer (must be at least 6 mo cancer-free) Beta-blockers Perimenopausal women, post-menopausal women experiencing hot flushes and not on hormone therapy Alcohol consumption greater than 7 drinks/wk Acute coronary syndrome within the last 6 mo, heart failure, pacemaker, and any additional contraindications to participation in exercise testing or an exercise training program.