Inclusion Criteria:  adult ICU patients ≥18 years confirmed COVID-19 infection on-Oxygen support (mechanical ventilation, face masks, nasal cannula, etc.) Previous history of omega-3-oil with discontinuation of at least 1 month prior to admission  Exclusion Criteria:  soya bean oil allergy fish allergy peanut allergy fish oil allergy pregnant women Continuous use of Omega-3-oil till admission