Inclusion Criteria:  Age of 18 years or above Must fully understand the protocol and sign written informed consent American Society of Anaesthesiologists Physical Status Classification System of 1 or 2 Body Mass Index above 18 kg/m^2 For fertile women, safe contraceptives for the last month and negative urine human chorionic gonadotropin is required  Exclusion Criteria:  Participants unable to cooperate Participants unable to speak or read Danish Age above 65 years Cardiovascular disease Allergy to study medication History of alcohol or substance abuse Intake of corticosteroids within the last 14 days Daily intake of prescription analgesia within the last four weeks Intake of over-the-counter analgesia within the last 48 hours Neuromuscular diseases or wounds on the arms or hands preventing adequate test or block performance. Diabetes mellitus