For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit: www.BMSStudyConnect.com  Inclusion Criteria:  Active Eosinophilic esophagitis (EoE) with histologic evidence as a peak count of ≥ 15 eosinophils per higher-power field at any 2 levels of the esophagus Previously received an adequate trial of proton-pump inhibitor medication that did not provide complete response to EoE EoE symptoms documented in daily diary during the screening period  Exclusion Criteria:  On a regimen of therapeutic anticoagulation Demonstrates evidence of immunosuppression or is receiving systemic immunosuppressive or immunomodulating drugs Currently receiving a high potency topical corticosteroid for dermatologic use  Other protocol-defined inclusion/exclusion criteria apply