Inclusion Criteria:  Age ≥ 18 years LF confirmed by RT-PCR (reverse-transcription polymerase chain reaction) Written informed consent  Exclusion Criteria:  Inability to give consent (e.g. unconscious patients/ cognitively impaired patients) Pregnancy/lactation (evidenced by negative urine pregnancy test in women of child-bearing potential) Women who plan to get pregnant within the upcoming 6 months Severe malnutrition (BMI<16) Known intolerance to ribavirin or favipiravir History of hemoglobinopathies (i.e., sickle-cell anaemia or thalassemia major) and/or haemophilia  Organ failure as evidenced by:  Creatinine ≥ 3x upper limit of normal (ULN) Aspartate aminotransferase (AST/GOT) > 150 IU/l Alert, confusion, voice, pain, unresponsive (ACVPU) score = V or P or U (corresponds to Glasgow Coma Scale (GCS) ≤ 12) Severe central nervous system features (e.g. seizures, restlessness, confusion and coma) O2 Saturation < 90% Hematocrit <30 % Severe anaemia requiring blood transfusion Inability to take oral drug (e.g. encephalopathy, severe vomiting) Patients who already received ribavirin or favipiravir within the preceding 7 days