Inclusion Criteria:  The patient voluntarily signs an informed consent form; Adult patients who meet the criteria for heat stroke; Heat stroke is defined as heat stroke (Heat Stroke, HS) is a serious fatal disease caused by heat injury factors acting on the body, accompanied by multiple organ damage.  Exclusion Criteria:  Age <18 years old or >90 years old; Patients with advanced tumors, Pregnancy or lactation; Patients who missed out during treatment and whose data are incomplete.