Inclusion Criteria:  Age is between 20-40 years old. Non PCOS patient. With no previous or current evidence of OHSS (number of oocyte between 5-15 oocytes) Normal Prolactin level. No other endocrinological abnormality including thyroid disorder or diabetes. Within normal ovarian reserve AMH(1-3) ng/ml No evidence of endometriosis. No other medical or surgical diseases.  10-Careful history, general and local examination, abdominal and vaginal ultrasonography and basal haematological and chemical investigations were done  to exclude any other abnormalities which can interfere with the result of the current study.  Exclusion Criteria:  Women older than 35 years of age or younger than 20 years old Women with polycystic ovary syndrome PCOS (as defined according to the Rotterdam criteria) Women who were diagnosed to have endometriosis within the last 1 year. Women with ovarian hyper stimulation syndrome (OHSS). Sever male factor infertility with immotile sperm which may affect embryo development poor responder patient .