Inclusion Criteria:  Aged > 18 years and < 65 years Hemifacial paralysis from 3 to 6 on the House-Brackmann scale Never treated with HA and BTX injection Signed informed consent Women of childbearing potential will only be included in the study if uptaking hightly effective birth control measures.  Exclusion Criteria:  Hypersensitivity to any component of the products used Diabetes, systemic disease, coronary artery disease, acute-chronic hepatitis C, autoimmune disease and/or other disease involving poor general health clotting problem. Peripheric neuro-musculars disorders, amyotrophic lateral sclerosis. Pregnant or lactating