Inclusion Criteria:  Rutherford grade 2-5. Femoral popliteal artery stenosis or occlusion, a clear outflow tract no less than 10cm long at the distal end of the knee should be continuous with a clear outflow tract under the ankle. Patients who understand the purpose of this study, volunteer to participate in the experiment, sign informed consent and are willing to follow up. The guide wire needs to pass through the lesion. Life expectancy> 24 months. Patients with thrombosis of the lower extremities, patients who received drug-coated balloon (DCB) intervention after thrombus removal through mechanical thrombus removal, percutaneous catheter thrombolysis, and thrombus removal. Patients who have received DCB intervention for both lower limbs can be enrolled in the group according to the intracavitary treatment time. There is at least one continuous infrapopliteal outflow artery or obtained through intravascular reconstruction. For combined aortic iliac artery disease, the blood flow can be recanalized after intravascular reconstruction without residual stenosis exceeding 50%.  Exclusion Criteria:  Patients with stroke, cerebral hemorrhage, gastrointestinal hemorrhage or myocardial infarction within 3 months before enrollment. Patients who are known to be allergic to heparin, aspirin, other antiplatelet drugs, contrast agents, etc. Patients who have participated in clinical trials of drugs or other medical devices that interfere with this clinical trial within the past 3 months. Pregnant and lactating women. Patients who are unable or unwilling to participate in this trial. Patients with Berg's disease. Patients who have undergone arterial bypass on the treatment side.