Inclusion Criteria:  Women who have reached the age of 20 and have not yet menopause. Myoma size≧4cm. Patients with submucosal fmyoma or intramural myoma of the uterus.  Exclusion Criteria:  Patients with subserosal myoma. Pregnant, breastfeeding or have menopause. Pelvic infections, vaginitis, cervicitis or endometritis and have not been cured. Malignant diseases of the cervix and uterus. Abnormal reports of clinical significance in Pap smear or thin-layer cell test. Abnormal blood coagulation function or liver and kidney function, with bleeding tendency. There is no safe puncture treatment route. Those who have installed intrauterine contraceptive device or Pacemaker. Those who cannot perform vaginal ultrasound, such as those who have no sexual experience and do not accept hymen repair.