Inclusion Criteria:  (1)The clinical diagnosis of CP/CPPS is exclusionary diagnosis.The main steps of diagnosing CP/CPPS are follwing: T  he chief complaint is long-term recurrent pain or discomfort of lumbosacral and perianal distension in the lower abdomen of the external perineum genital area and the superior pubic area (more than 3 months). Bacterial prostatitis will be eliminated by routine culture of prostatic fluid and urine culture before and after prostatic massage. Urinary tract infection will be ruled out by routine urinalysis and sediment examination.  (2)Total score of NIH-CPSI ≥ 15.  Exclusion Criteria:  The participants would be excluded if they got any acute or chronic infectious disease, other chronic pain diseases, internal organic diseases, history of malignant tumors, and chronic diseases that might contribute to peripheral nerve injury like diabetes mellitus and hypertension.  Prostate changes will be observed by prostate ultrasound and other urogenital and pelvic space-occupying lesions will be excluded.  Contraindications of fMRI scan like claustrophobia and denture implantation status are also considered.