Inclusion criteria:  To have signed the written informed consent before starting any procedure related to the study. Sexual abstinence (2 to 5 days). To be a male patient who delivers a fresh seminal sample for diagnosis or artificial insemination treatment. To be a male donor who delivers a fresh seminal sample for donation or for previous tests to include him in the donation programme. To be a female patient undergoing artificial insemination.  Exclusion criteria:  Use of sperm of testicular or epididymal origin. Cryptozoospermia or oligozoospermia with sperm concentration <1 mill/ml. Ejaculates obtained with more than 5 days of sexual abstinence. Frozen semen samples for artificial insemination cycles with partner's semen. Female patients who present uterine malformations that compromise the viability of the pregnancy (intramural or submucosal fibroids > 3 cm, polyps, adenomyosis or congenital or acquired malformations). Female patients with hydrosalpinx. Patients who have suffered two or more previous abortions (repeated abortions). Patients with a body mass index greater than 30 Kg / m2.