Inclusion Criteria:  Adults age 18-55 Body mass index (BMI) 27-45 kg/m2 Live or work within 30 miles of the University of Colorado Anschutz Health and Wellness Center Passing medical and physical screening Agree to fast for 12 hours before the baseline and follow-up visits Sedentary: defined as <150 minutes per week of voluntary exercise at moderate intensity or greater and < 60 min per day of total habitual PA (i.e. work related, transportation related) at moderate intensity or greater, over the past 3 months. Not currently practicing yoga regularly over past 6 months Among women: Not currently pregnant or lactating, not planning to become pregnant in the next 12 weeks English speaking, as the intervention will be delivered in English  Exclusion Criteria:  Diastolic blood pressure > 100 mm HG or systolic blood pressure > 160 mm HG Resting heart rate >100 Diabetes (fasting glucose ≥126 mg/dL or Hemoglobin A1C ≥6.5%) Undiagnosed hypo- or hyper-thyroidism (TSH outside of the normal range) or history of uncontrolled thyroid disorder. Abnormal values of: hematocrit, white blood cell count or platelets Triglycerides > 400 mg/dL LDL cholesterol >200 mg/dL Abnormal resting electrocardiogram (ECG) Presence or history of any self-reported metabolic or chronic health problems which would affect appetite, food intake, energy metabolism, or ability to optimally participate in the exercise component Significant self-reported pulmonary disorders including: chronic obstructive pulmonary disease (COPD), interstitial lung disease, cystic fibrosis, or uncontrolled asthma. Self-reported symptoms suggestive of CVD: chest pain, shortness of breath at rest or with mild exertion, syncope. Regular use of prescription or over-the-counter medications known to significantly impact appetite, weight, or energy metabolism Regular use of systemic steroids (other than Oral Contraceptive Pills). Regular use of obesity pharmacotherapeutic agents within the last 6 months. Previous obesity treatment with surgery or weight loss device Current alcohol or substance abuse Nicotine use (past 6 months) History of clinically diagnosed eating disorders including anorexia nervosa, bulimia, binge eating disorder. Current severe depression or history of severe depression within the previous year History of other significant psychiatric illness (e.g. psychosis, schizophrenia, mania, bipolar disorder) which in the opinion of the Study MD would interfere with ability to adhere to dietary or exercise interventions. Currently participating in or planning to participate in any formal weight loss or physical activity programs or clinical trials. Participation in a weight loss program using the Colorado Weigh curriculum within the past 3 years Weight loss >5kg in past 3 months for any reason except post-partum weight loss Weight loss of >50 lbs in past 3 years for any reason except post-partum weight loss.