Inclusion Criteria:  Patients with STEMI and residual non culprit CAD Informed consent  Exclusion Criteria:  Refusal or inability to provide informed consent. < 18 years of age Cardiogenic shock Previous Coronary Artery Bypass Grafting (CABG Indication for revascularization by CABG. eGFR < 30 ml/min/m2 ULM stenosis Estimated life expectancy < 3 year Non culprit CTO lesion