Inclusion Criteria:  Patient is male or non-pregnant female at least 18 years of age.  Clinical diagnosis of moderate to severe papulopustular acne rosacea as determined by:  Investigator's Global Assessment (IGA) at Randomization score of 3 or 4. Patient has at least 15 inflammatory lesions on the face  Patient is willing to apply the Investigational Product as directed  Patient is willing and able to comply with the protocol  Exclusion Criteria:  Patient is pregnant or planning to become pregnant Patient is taking a topical therapy on the face which may affect the patient's rosacea