Inclusion Criteria:  ≥18 years old Onset of a minor stroke (National Institute of Health stroke scale, NIHSS≤3) and TIA elapsed time from last episode to registry <1 month  Exclusion Criteria:  patients who refused to participate in the research, and patients who failed to complete the follow-up protocol.  patients with malignant tumors, or patients with severe liver or kidney disease, whose life expectancy is less than 1 year.  patients who received endovascular or thrombolytic therapy.