Inclusion Criteria:  Adult patient (> or = 18 years of age) Patient with symptoms of COVID-19 (Rhinitis, throat pain, nasal congestion or other signs of local manifestation of the disease in the upper respiratory tract, including loss of taste, with or without additional systemic symptoms such as fatigue, fever, muscle pain...) whose health condition does not require hospitalization (mild to moderate disease) Patient with these symptoms for 5 days or less with a median of 3 to 4 days. Patient with consent to participate in the study  Exclusion Criteria:  Patient with an age below 18 years Patient under legal protection (guardianship, curatorship) Patient without upper respiratory tract symptoms Patients with symptoms for more than 5 days Patient with previous COVID-19 diagnosed by RT-PCR Patient vaccinated against SARS-CoV-2 (1 or 2 injections) Hospitalized patient Refusal to participate