Inclusion Criteria:  Patients older than 18 years without previous history of Hp infection or eradication undergoing a gastroscopy  Exclusion Criteria:  Patients taking oral anticoagulants (acenocoumarol and new anticoagulants as dabigatran, rivaroxaban, apixaban and edoxaban), NSAIDs or with intake of antibiotics in the last 4 weeks, but aspirin at a dose of 100 mg per day will be included Diseases that affect the gastric mucosa and preclude the evaluation of the collecting venules pattern (portal hypertension, gastric lymphoma) History of previous gastric cancer or patients in surveillance for preneoplastic lesions (atrophic gastritis/IM), Previous gastric surgery, Active bleeding or presence of blood or food that would impede a complete mucosal evaluation. Negative to participate in the study or inability to provide signed consent