Inclusion Criteria:  Patients must have a Karnofsky (adult) Performance Status of at least 70%. Patients must have adequate organ function  Exclusion Criteria:  Female patients who are pregnant or breast-feeding Active viral, bacterial or fungal infection Patient seropositive for Human Immunodeficiency Virus (HIV-I /II); Human T-Cell Lymphotrophic Virus (HTLV -I /II) Presence of leukemia in the Central Nervous System (CNS).