Inclusion Criteria:  patients with head and neck cancer, included nasopharyngeal carcinoma, laryngeal cancer, oropharyngeal cancer, ear and oral cancer, hypopharyngeal cancer, salivary-gland carcinoma. Aged between 20 years old to 75years old, no gender difference. patients with head and neck cancer has not received surgery yet, and will plan to accept chemotherapy and/or radiotherapy. recurrent head and neck cancer, and expect to received chemotherapy and/or radiotherapy. patient with vital sings stableness, conscious clear, and have ability to recognize the contain of trail and sign consent. not accept other adjuvant therapy. no brain metastasis or psychosis, and will to join whole course as well as accept assessments.  Exclusion Criteria:  Aged less than 20 years old and over 75 years old。 Patients be diagnosed with head and neck cancer, and accepted surgery, or already finished chemotherapy and/or radiotherapy. patient with brain metastasis, conscious unclear, and have not able to recognize the contain of trail and sign consent. Accept other adjuvant therapy and chemotherapy and/or radiotherapy simultaneously. Combined with serious organs failure。 Have contraindication in chemotherapy or radiotherapy.