Inclusion Criteria:  English speaking patients in the age range 18 - 100. Patients suffering from Irritable Bowel Syndrome, Inflammatory Bowel Disease, Diabetes, Gastroparesis, will be included. Patients suffering from Collagen disorders such as Alport Syndrome, Ehlers-Danlos Syndrome, Goodpasture Syndrome. Patients suffering from plexiform neurofibromas. Patients with bariatric surgery. Patients with appendicitis. Patients with scleroderma.  Exclusion Criteria:  Patients suffering from HIV, Hepatitis C, and other infectious diseases that require the handling of tissues in a Bio-safety level 3 environment. Patients suffering from infectious enteric disorders. Patients without any Gastrointestinal disorders (i.e. healthy volunteers).