Inclusion Criteria:  Pregnant women aged ≥18 at time of conception Case subjects are at high risk of PET by NICE guidelines ( ≥1 high risk factor or >1 moderate risk factor) or high risk of SGA by RCOG Guidelines (≥1 major risk factor or ≥3 minor risk factors). Control subjects do not meet this criteria  Exclusion Criteria:  Maternal age <18 years of age at time of booking Fetal structural or genetic abnormality Multiple pregnancy Known underlying maternal cardiac condition