Selection Criteria:  Male patient volunteers aged 20 to 45 years (limits included); Socially insured patient receiving benefits from the French Social Security's health branch  Non-Selection Criteria:  Patients suffering from infertility of infectious or genetic origin, or from a pathology requiring concomitant medical treatment; Consumption of dietary supplements during the previous 3 months and during the course of the study; Smoking ≥ 5 cigarettes/day; Alcoholism ≥ 10 drinks (alcohol standard)/week ; Body Mass Index (BMI) not between [19 and 29] (inclusive). Occupation at risk of exposure to carcinogenic, mutagenic and toxic agents for reproduction defined according to articles R.4412-2 2°, R.4412-3 and R.4412-60 of the French Labour Code; Patient unable to give consent; Minors and protected adults, vulnerable persons; Patient participating in another clinical research study  Inclusion Criteria:  Sperm DNA fragmentation rate ≥ 30 %  Exclusion Criteria:  Positive semen culture