Inclusion Criteria:  Adult patients (18 years old and above) undergoing General Anaesthesia for noncardiac surgery requiring the use of a neuromuscular blocking agent.  Exclusion Criteria:  Use of different types of neuromuscular blocking agents for the same patient within the same surgical procedure. Known Neuromuscular diseases/syndromes judged to condition accurate neuromuscular monitoring. Known acute or chronic hepatic disease.