Inclusion Criteria:  Male or female patients aged over 18 years (inclusive); ECOG score: 0 - 2 points Patients with histologically or cytologically confirmed locally advanced or metastatic solid tumors, including TNBC and HNSCC No previous treatment with CPI Agreement to provide a previously archived tumor tissue specimen or biopsy to collect tumor lesion tissue Subject has at least 1 measurable lesion as defined by RECIST V1.1 Expected survival ≥ 6 months Adequate organ function Males of childbearing potential or females of childbearing potential must use highly effective contraceptive methods during the trial and continuing for 6 months after the last dose The subject voluntarily joined the study and signed an informed consent form  Exclusion Criteria:  Pregnant or lactating women; Prior cell therapy; Received systemic anti-tumor therapy within 2 weeks or 5 half-lives of the treatment agent (whichever is shorter) before the start of treatment; Previous or current presence of two or more primary tumors Patients with active autoimmune diseases Have received systemic treatment with corticosteroids (10 mg prednisone equivalent daily) or other immunosuppressive agents for more than 7 days within 2 weeks before the start of treatment Received investigational drugs within 2 weeks before the start of treatment; Major surgery or serious trauma within 4 weeks before the start of treatment; Patients with symptomatic central nervous system (CNS) metastasis Active viral infectious disease requiring systemic treatment at screening: Known serious hypersensitivity history Uncontrolled pleural effusion, ascites, or pericardial effusion at screening; Presence or history of active interstitial lung disease; Patients with hypertension that cannot be well controlled with medical therapy. Presence of clinically significant cardiovascular disease Deep venous thrombosis within 6 months before the start of treatment Thrombolytic therapy within 10 days prior to the start of treatment Any active infection requiring intravenous anti-infective therapy before the start of treatment Had toxicity not resolved to ≤ Grade 1 (CTCAE 5.0) from previous anticancer therapy Known or suspected inability to comply with the study protocol