Inclusion Criteria:  Adults between 20-60 years old, No heart, liver, kidney, endocrine and major organic diseases  Exclusion Criteria:  Renal insufficiency and dialysis Cancer Underweight (BMI≦17) or obese (BMI≧27), Take chronic disease drugs, Blood pressure systolic blood pressure ≧130 mmHg or diastolic blood pressure ≧85 mmHg, Too high fasting blood glucose ≧ 100 mg/dL, Triglyceride ≧ 150 mg/dL,Total cholesterol ≧ 200 mg/dL, Have a history of vitamin C allergy, People with mental illness, Pregnant or breastfeeding women, Hematosis, Kidney stones, Long-term vitamin C supplements (at least 200 mg per day for more than one month)