Inclusion Criteria:  Men and women aged ≥ 18 years. Diagnosed with T1D of at least 6 months of evolution. Patients who give their informed consent in writing.  Exclusion Criteria:  Active alcoholism> 30 g / day in men and> 20 g / day in women. Known non-metabolic liver disease: alcoholic hepatitis, viral hepatitis from HBV infection and / or HCV, hemochromatosis, Wilson's disease, α-1 antitrypsin deficiency, autoimmune hepatitis, hepatic granulomatous (tuberculosis, mycobacteria, histoplasmosis), hepatic lymphoma, primary neoplasia liver, liver metastasis. Active treatment with hepatotoxic drugs: amiodarone, isoniazid, rifampicin, sulfa drugs, tetracyclines, amoxycline / clavulanate, ketoconazole, methotrexate, valproic acid, trazodone, tamoxifen, methyldopa, reverse transcriptase inhibitors, chemotherapy, immunotherapy. Pregnant women. Acute decompensation of T1D (ketoacidosis) in the 3 months prior to inclusion. The inclusion after this period.