Inclusion Criteria:  Ability to provide consent and willing, and able to comply with study procedures Ability to read and speak English  GROUP I:  Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM or PALB2 germline genetic mutation No strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer) Age >= 50 years old at time of consent.  GROUP II:  Documentation of pathogenic or likely pathogenic germline BRCA 1 and 2, ATM, or PALB2 germline genetic mutation Has strong family history of pancreatic cancer (defined as having >= 1 first-degree or second-degree relative with a history of pancreatic cancer) Age >= 18 years old at time of consent (screening generally begins 10 years prior to the earliest pancreatic cancer in the family)  Exclusion Criteria:  Prior or active pancreatic cancer. Pregnant women are excluded from this study because effects of an MRI on developing fetus is unknown.