Inclusion Criteria:  Having a COPD (COPD was confirmed if the post-bronchodilator forced expiratory volume in one second (FEV1) divided by the forced vital capacity (FVC) was less than 0.7 (FEV1/FVC<70%) Having been admitted at least twice in the previous year or three times in the two previous years for a COPD exacerbation (eCOPD).  Exclusion Criteria:  Another significant respiratory disease. An active neoplasm. A terminal clinical situation. Inability to carry out any of the measurements of the project. Unwillingness to take part in the study.