Inclusion Criteria:  age between 18 and 75 inclusive; histologically confirmed colon adenocarcinoma; having undergone a curative resection of stage I, II or III colorectal cancer; diagnosed T1 / T2 / T3 / T4 and N0 / N1 / N2; eligible to receive 6 months of adjuvant chemotherapy; having given free, informed and written consent; agreeing to the use of a tumor sample for research purposes; being affiliated to a social security system.  Exclusion Criteria:  pregnant or breastfeeding women legal incapacity or physical, psychological, social or geographical conditions preventing the patient from signing the consent or completing the study. history of other solid tumor within 3 years before inclusion, with the exception of in-situ cancer of the cervix and skin cancers (basal or squamous) treated and controlled person subject to a safeguard measure.