Inclusion Criteria:  The subjects will only be recruited into the study if participants have met all the following criteria:  Ages between 25 and 60 years. Previous or current diagnosis of MTrP in the upper trapezius region according to the criteria in reference 1 active/latent MTrP in the upper trapezius region  The diagnostic criteria to establish myofascial trigger point is adopted from prior investiogators and include:  Presence of palpable taut band in the skeletal muscle Presence of hypersensitive tender spot in the taut band Presence of local twitch response upon stimulation of the taut band Reproduction of referred pain upon palpation Presence of spontaneous referred pain pattern  Exclusion Criteria:  Exclusion criteria: Any subject that exhibits any of the following criteria will excluded from the study: Pregnancy or immunocompromise Fever/infection Previous history of whiplash injury Previous history of cervical surgery, cervical radiculopathy, or myelopathy Severe disc or cervical lesion Evidence of cognitive deficit Degenerative or inflammatory disease of the cervical spine or shoulder, fibromyalgia, or neuromuscular diseases Use of medications (anticoagulants, anti-inflammatory etc.) or illicit drug use (1 week prior to treatment or follow up) Received treatment for MPS a month before the study recruitment