the patience group Inclusion criteria:  Clinical manifestations: fluctuating eye muscle weakness; Positive ice test, fatigue test, rest and sleep test; Positive neostigmine test; Serum acetylcholine receptor antibody and other antibodies are positive; Repeated electrical nerve stimulation test attenuation is positive; Meeting the above diagnostic criteria of the first, or any of the other 4, at the same time excluding other diseases caused by eye palsy can be clear diagnosis.  the patience group exclusion criteria:  General myasthenia gravis; History of other eye diseases With other autoimmune diseases or other inflammatory diseases; Patients with diabetes, hypertension, coronary heart disease and other chronic medical history or cancer diseases; Hepatitis B virus, hepatitis C virus, HIV, syphilis positive patients; immunosuppressive drugs (such as glucocorticoid, azathioprine and cyclosporine A), gamma globulin for intravenous injection, plasmapheresis, etc., within 3 months before treatment; Previous thymic resection or thymus radiation therapy; Pregnancy or lactation.  the control group Inclusion criteria:  No obvious abnormality was found in the recent physical examination results; No history of autoimmune diseases; Have not received antiviral therapy or immunotherapy within 3 months; No history of other eye diseases or systemic diseases.