Inclusion Criteria:  Male or female aged 18 to 75 years (inclusive) at the time of signing informed consent. Clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before Day 1. HS lesions present in at least 2 distinct anatomical areas. Total AN count ≥ 5. Draining fistulas ≤ 20. Stable HS for at least 6 weeks prior to Day 1 visit.  Exclusion Criteria:  1. Concomitant dermatological or medical conditions that may interfere with the Investigators' ability to evaluate the subject's response to therapy.