Inclusion Criteria:  On-pump cardiac surgery; Off-pump Cardiac Surgery; Informed and written consent of the patient or inclusion according to the emergency procedure; Affiliated patient or beneficiary of a social protection.  Exclusion Criteria:  Patients who underwent cardiac surgery for congenital heart disease. Patients who underwent emergency heart surgery. patients who, within the last 72 hours before surgery, were injected with iodinated contrast (because of its potential nephrotoxicity). patients with chronic Kidney disease. 5- patients with a preoperative serum creatinine >2 mg/dL. patients who died within the first 24 hours after surgery. patients on mechanical ventilation before intervention. Patients with preoperative medical disorders other than cardiac affection.