Inclusion Criteria:  Topographic evidence of keratoconus: maximum corneal curvature (Kmax) ≥47.00 D, localized steepening on topographic maps, localized elevation in the anterior and posterior corneal surfaces.  Exclusion Criteria:  Hypersensitivity to riboflavin Thinnest corneal pachymetry < 380 μm History of corneal surgery, including previous cross-linking Corneal scarring Aphakia Pseudophakia Any visually significant ocular condition