Inclusion Criteria:  ≥ 18 years of age Diagnosis of breast cancer requiring surgical lymph node evaluation either by sentinel lymph node biopsy or axillary lymph node dissection Surgery at University of Wisconsin Hospital and Clinic  Exclusion Criteria:  Pregnant or breast feeding Unable to provide informed consent Allergy to indocyanine green Patients with clinically positive lymph nodes undergoing sentinel lymph node biopsy, with or without axillary lymph node dissection, after neoadjuvant chemotherapy