Inclusion Criteria:  Males 18-89 undergoing HoLEP Willing to sign the Informed Consent Form Able to read, understand, and complete patient questionnaires, pain texts, and medication diary  Exclusion Criteria:  Allergy or hypersensitivity to TXA, history of acute venous or arterial thrombosis, intrinsic risk for thrombosis or thromboembolism, history of thromboembolic disease, hereditary thrombophilia, use of hormonal agents Patients having any additional simultaneous procedure other than a HoLEP (cystolitholapaxy allowed). Anticipated need for perineal urethrostomy at the time of HoLEP Patient not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital