Inclusion Criteria:  Diffuse macular edema without focal edema source accessible by focal laser (e.g. capillary telangiectasia) Central retinal thickness ≤ 400microns. Patient does not meet the reimbursement criteria for intra-vitreous injections(IVI) of anti-VEGF (eg AV> 5/10). IVI are contraindicated. Physician considers that it is preferable to space out the injections because of the side effects (eg. ocular disturbance during IVI, eye pain, sensation of a foreign body, spots in the visual field generating a visual gene etc.) Patient wishing to space the anti-VEGF IVI.  Exclusion Criteria:  Macular edema of a different etiology than diabetic macular edema or venous thrombosis (e.g. cataract extraction, vitreomacular traction, epiretinal membrane etc.) Central retinal thickness > 400 microns. The eye presents a focal edematous maculopathy accessible to conventional laser.