Inclusion Criteria:  Age ≥ 20 years. Patients must have a histological or cytologically confirmed diagnosis of advanced or recurrent malignant solid tumors. Patients have received all currently available standard treatments (unless the therapy is contraindicated, intolerable or unavailable due to any reasons). Patients must have measurable or evaluable disease (according to RECIST 1.1) Eastern Cooperative Oncology Group (ECOG) Performance Status ≤ 2 Must agree to take sufficient contraceptive methods to avoid pregnancy during the study and until at least 6 months after ceasing study treatment Patients must have fully understood and voluntarily signed informed consent form (ICF) for this study.  Exclusion Criteria:  Patients who received other investigational products or devices in other clinical trials within 4 weeks before the first dose. Patients who received anti-tumor therapy within 4 weeks, or within 5-half-lives (which is longer) before the first dose, including but not limited to chemotherapy, radiotherapy (palliative radiotherapy is completed at least 2 weeks before the first dose can enrol), targeted therapy or immunotherapy. Patients who have previous toxicity of anti-tumor therapy that has not recovered to Grade 1. (except for ≤ Grade 2 alopecia, chemotherapy-induced peripheral neurotoxicity, and ototoxicity). Patients who have gastrointestinal disorders that will affect oral administration or the Investigator judges that the absorption of TT-00434 will be interfered. Patients underwent major surgery (except biopsy) within 4 weeks, or the surgical incision has not completely healed prior to the first dose. Patients who have active bacterial or fungal infections (CTCAE, Grade ≥ 2) that required systemic treatment within 2 weeks prior to the first dose. Patients who have active HBV infection (HBV DNA copies ≥ ULN) and/or HCV infection (HCV RNA copies ≥ ULN) Patients who test positive for human immunodeficiency virus (HIV) or known acquired immunodeficiency syndrome. Has received a live-virus vaccination within 30 days of planned first dose NOTE: Seasonal flu vaccines are permitted. Known or suspected drug hypersensitivity to any ingredients of TT-00434 tablets. Female patients in pregnancy or lactation. Male patients or female patients at reproductive ages who are unwilling to receive effective contraceptive measures. Patients who are judged by the Investigator to be unsuitable for this study.