Inclusion Criteria:  Patient with cardiac surgery With iron deficiency with or without anemia  Exclusion Criteria:  Anemia without iron deficiency Iron overload Jehovah's witnesses Endocarditis Treating neoplasia Uncontrolled hypertension With infection Alfa-epoetin hypersensitivity Hypersensitivity of hamster's protein Erythroblastopenia induced by erythropoietin Ferinject or mannitol allergy