Inclusion Criteria:  Group 1 : Patient over 18 years old, Patient informed and not opposed to participate Patient followed for an autoimmune or inflammatory disease (vasculitis, systemic lupus, systemic sclerosis, non-infectious uveitis) Treatment with immunosuppressant and / or immunomodulator Group 2 : Patient over 18 years old, Patient informed and not opposed to participate Patient not followed for an autoimmune or inflammatory disease (vasculitis, systemic lupus, systemic sclerosis, non-infectious uveitis) Absence of treatment with immunosuppressant and / or immunomodulator  Exclusion Criteria:  Contraindication to vaccination Progressive cancer Pregnant or breastfeeding woman Current infection less than 3 weeks old Weight less than 40 kg Patient under tutor- or curator-ship Patient without health insurance