Inclusion Criteria:  patients admitted to ICU with or without breast cancer (non-metastatic) comorbidity age 18-85 years' old moderate to sever confirmed COVID 19 infection through PCR and CT male or female confirmed Covid-19 by PCR Requiring ICU admission  WITH evidence of severe COVID-19 (at least 2 of the following):  Fever > 38C within 72 hours Pulmonary infiltrate on chest X ray /ground glass opacity Need for supplemental O2 to maintain saturation > 92%  AND at least 1 of the following:  Ferritin > 500 ng/ml CRP > 50 mg/L LDH >250 U/L D-dimer > 1000 ng/mL all patient assigned informed consent  Exclusion Criteria:  above 85 years' old metatastic breast cancer autoimmune disease patients Unable to provide verbal informed consent preganncy Subjects between the ages of 70 and 75 will be excluded if they have NYHA Class III/IV heart failure Active TB Receipt of IV tocilizumab for the treatment of a non-COVID condition within 3 weeks of the first COVID symptom History of hypersensitivity to tocilizumab 7. ANC <500, Platelets <50,000* 8. AST/ALT > 5X ULN