Inclusion Criteria:  Male or non-pregnant and non-lactating females aged 21-55 years Report monthly use of cannabis (≤1 day per week) over the 6 months prior to screening, Not currently seeking treatment for their cannabis use Have a Body Mass Index from 18.5 - 34kg/m2. Able to perform all study procedures Must be using a contraceptive (hormonal or barrier methods)  Exclusion Criteria:  Meeting DSM-V criteria for moderate-severe Cannabis Use disorder (CUD) or any substance use disorder other than nicotine, caffeine, or mild CUD Any other Axis I disorder Report using other illicit drugs in the prior 4 weeks Current use of prescription analgesics, or any medications that may affect study outcomes If medical history, physical and psychiatric examination, or laboratory tests performed during the screening process are not within the normal range and / or reveal any significant illness (e.g., hypertension) as judged by the study physician and to put the participant at greater risk of experiencing adverse events due to completion of study procedures. Current pain Pregnancy is exclusionary due to the possible effects of the study medication on fetal development. History of an allergic reaction or adverse reaction to cannabis is exclusionary. History of respiratory illness or current respiratory illness Currently enrolled in another research protocol Not using a contraceptive method (hormonal or barrier methods) Insensitivity to the cold water stimulus of the Cold Pressor Test Any disorders that might make cannabis administration hazardous are exclusionary, as determined by the evaluating physician