Inclusion Criteria:  The subjects to be studied will include female patients ages 18 and older of any race, identified as carrying an elevated risk for breast cancer referred to MDACC. High risk may be defined as having a calculated lifetime risk >20%, histopathology of lobular neoplasia or atypical ductal hyperplasia, atypia NOS or a genetic mutation known to predispose the patient to breast cancer.  Exclusion Criteria:  Subjects who are pregnant will be excluded as MBI exam involves injection of radioactive tracer contrast enhanced MRI involves gadolinium injection, both of which are contraindicated during pregnancy.