Inclusion Criteria:  Crohn's disease diagnosed according usual criteria Bowel resection with ileocolonic anastomosis performed removing all inflammatory lesions Postoperative endoscopy performed between 6 and 12 months after ileocolonic anastomosis reaching the neoterminal ileum (patients who underwent a two stage surgical procedure are also eligible if the endoscopic evaluation is performed 6-12 months after restoration of the fecal stream) Moderate endoscopic postoperative recurrence classified i2 according to the Rutgeerts score at 6-12 months, validated by a blinded central reading  Exclusion Criteria:  Patients with an ostomy Ulcerative colitis or IBD type unclassified Ileorectal or ileal pouch-anal anastomosis GETAID_2021-01_POMEROL_protocol_20210714_v1.2 6 Symptoms defined as average daily SF ≥ 3.5 and average daily AP score ≥ 1.5 having started after a free interval without symptoms of at least one month after surgery Patients with obstructive symptoms of CD defined by a CDOS > 4 Patients exposed to infliximab before index surgery with a primary non-response (no clinical effect after 2 infusions at the discretion of the treating gastroenterologist) or history of infusion reactions to infliximab or history of detectable anti-infliximab antibodies Patients treated with biological therapy (except for intraocular injections) or an investigational medical product after index surgery Patients having started thiopurines or methotrexate more than 6 weeks after ileocolonic anastomosis with restoration of the fecal stream Patients in whom not all inflammatory lesions have been removed at index surgery Patients with active perianal Crohn's disease Patients with a contraindication to infliximab: cancer in the 5 years prior to inclusion excluding non-melanoma skin cancer, active tuberculosis or untreated latent tuberculosis, moderate or severe heart failure, HIV or HBV infection (serology < 6 months), recent live vaccination (within 4 weeks of baseline) Pregnant women Patients under legal protection or unable to express their consent. Patients not affiliated to a health insurance system. Patients deprived of liberty by judiciary or administrative decision or hospitalized without consent or admitted in a sanitary or social institution for another reason than research.