Inclusion Criteria:  Signing of written informed consent of the patient to participate in a study Age from 25 to 50 years old Established diagnosis: tooth loss (K08.1- ICD 10), vitamin D3 imbalance. Patients who are medically stable  Exclusion Criteria:  Refusal of the patient from further participation in the study Pregnancy diagnosed after the inclusion into the trial Non-compliance by the patient with postoperative recommendations. Residence address change