Inclusion Criteria:  Age 18-65 years Refraction errors, dry eye, or blurred vision Have a willingness to participate in the study  Exclusion Criteria:  Uncontrolled disease Have complications during the study Have astaxanthin more than 2 weeks Allergic to astaxanthin, seafood, or seaweed Osteoporosis or thyroid disease Immunodeficiency or taking immunosuppressants Liver and kidney diseases A person with a brain disorder, vision or hearing unusual Pregnancy or lactation Cannot follow the protocol During participated in other studies