Inclusion Criteria:  men and women aged 18-70; Patients with nervous system diseases (such as stroke, amyotrophic lateral sclerosis, brain trauma, multiple sclerosis, Alzheimer's disease, etc.) accompanied by non random emotional expression disorder; The informed consent form signed by the subject indicates that the subject has been informed of all the contents related to the study; The subjects are willing and able to comply with the study visit schedule, treatment plan, laboratory examination and other study procedures.  Exclusion Criteria:  patients with acute infection, acute trauma, perioperative period and acute attack of chronic diseases; Patients in critical condition or dying can not participate in this study; Pregnant or lactating women; Substance abuse patients; Allergic to Deanxit; Mental disorder; Coma; Untreated angle closure glaucoma; In the early recovery of myocardial infarction, patients with different degrees of heart block or arrhythmia and coronary artery ischemia; Monoamine oxidase inhibitors were used; Participated in any other studies involving studies or post marketing drugs within 30 days prior to screening; According to the judgment of the researcher, there are other serious acute or chronic medical or psychiatric conditions or laboratory abnormalities that may increase the risks associated with participating in the trial or using the research products, or may affect the interpretation of the research results, which may make the subjects unsuitable for participating in the trial; Inability and / or unwillingness to understand and / or comply with the protocol.