Inclusion Criteria:  Males of any race between 35 and 55 years of age Body mass index between 18.0 and 30.0 kg/m2 In good health Males will agree to use contraception Able to comprehend and sign an informed consent form History of a minimum of 1 bowel movement per day  Exclusion Criteria:  History of significant medical illness History of clinically significant drug allergy History of a seizure disorder, not including infantile seizures History of stomach or intestinal surgery that would potentially alter absorption and/or excretion of orally administered drugs Clinically significant medical treatment within 8 weeks or infection treatment within 4 weeks of dosing Clinically significant ECG abnormality History of alcoholism or drug/chemical abuse within the previous 2 years or positive screening test Significant alcohol consumption Positive hepatitis panel and/or positive human immunodeficiency virus test Use of prohibited prescription, over-the-counter medications or natural health products Use of tobacco or nicotine-containing products within 3 months prior to Check-in or positive screening test Receipt of blood products within 2 months prior to Check in Recent donation of blood, plasma, or platelets prior to Screening Exposure to significant diagnostic, therapeutic or employment in a job requiring radiation exposure monitoring within 12 months prior to Check-in Evidence or history of active suicidal thoughts in the previous 5 years or have any lifetime history of a suicide attempt Not suitable for study in the opinion of the Principal Investigator