Inclusion criteria:  - All patients >/= 18 undergoing atrial fibrillation ablation  Exclusion Criteria:  Patients unable to receive or tolerate colchicine Pregnant or lactating women Concomitant use of drugs interacting with colchicine (including: cyclosporin, ranolazine, tacrolimus, clarithromycin, indinavir, itraconazole, ketoconazole, nefazadone, ritonavir, saquinavir, suboxone, telithromycin, erythromycin, fluconazole, verapamil, diltiazem, or more than 1 glass grapefruit juice daily) Severe renal impairment (CrCl < 30 mL/min) Severe hepatic impairment (ALT/AST greater than 5x ULN or clinical cirrhosis) Ongoing current use of colchicine.