Inclusion Criteria:  16-45 years of age Diagnosis of BD (clinically euthymic) according to the DSM-5 Diagnosis of PMDD according to the DSM-5 Regular menstrual cycles No contraindication to use oral contraceptives Capable of consent for treatment  Exclusion Criteria:  Smoking and over the age of 35 Current or recent (last month) use of systemic estrogen or progesterone treatment Severe reactions to hormone treatment Pregnant or breastfeeding Current substance use disorder Oophorectomy or hysterectomy Current unstable medical conditions History of current or past breast cancer, pancreatitis, migraines or blood clotting disorders.