Inclusion Criteria:  Male and female patients between 18 and 75 years of age, Patients having confirmed IBS according to Rome IV criteria (newly and previously non-responder to treatment), Pain/ discomfort score strictly above 1 and strictly below 6 as determined on a pain/ discomfort scale using arbitrary grading from 0 to 7 in 7 days preceding the inclusion visit, Not hypersensitive to any of the ingredients of the drug.  Exclusion Criteria:  Patients with an organic intestinal disease (Crohn's disease, ulcerative colitis, etc.), Pregnant females Treatments likely to influence IBS (anti-depressants, opioids, and narcotic analgesics) Patients with chronic alcoholism, vegetarian or vegan regimens Eating disorders such as anorexia or bulimia Documented food allergies.