Inclusion Criteria:  Age ≥40 years old (regardless of gender) Complete 3-day dietary record, Mini-mental state examination and Clinical dementia rating assessment Independent physical activity  Exclusion Criteria:  No amputation, edema, cancer, terminal case, thyroid disease and stroke include stroke history No family support Psychological problem Extremely data of dietary record(< 500 kcal or > 3500 kcal)