Inclusion Criteria:  All patients meeting the following criteria will be considered for participation in the study:  Male or female aged 18 or above; EUS is needed to further clarify the characteristics of digestive tract diseases; Patients able to give informed consent were eligible to participate. Able and willing to comply with all study process.  Exclusion Criteria:  All patients meeting the following criteria will not be considered for participation in the study:  Has participated in other clinical trials, signed informed consent and was in the follow-up period of other clinical trials. Has participated in clinical trials of the drug and is in the elution period of the experimental drug or control drug. Drug or alcohol abuse or psychological disorder in the last 5 years. Patients in pregnancy or lactation. A history of Upper Gastrointestinal surgery. Patients with anatomical abnormalities of the upper gastrointestinal tract due to advanced neoplasia Patients in whom the presence of clearly defined vital anatomical structures cannot be observed Researchers believe that the patient is not suitable to participate in the trial.