Inclusion Criteria:  65 < age <80, or 60 ≤ age ≤65 and is ineligible for autologous stem cell transplantation as assessed by the investigator Histopathological confirmed MCL and either expression of cyclin D1 or t (11;14) chromosomal translocation (in association with CD20). The verification will be based on central review of the local pathology report. No previous systemic treatment for MCL. ECOG physical strength score is 0-2. Expected survival time >6 months. Voluntary written informed consent prior to screening.  Exclusion Criteria:  Uncontrolled or significant cardiovascular diseases History of stroke or intracranial hemorrhage within 6 months before first administration of study treatment. Any mental or cognitive impairments which may limit the subject 's understanding and execution of informed consent as well as study compliance; Pregnant or breastfeeding women and those who do not agree to take contraceptive measures. Conditions in which a potentially life-threatening illness or severe organ dysfunction is not considered appropriate by the investigator.  Note: Other protocol defined Inclusion/Exclusion criteria may apply.