Inclusion Criteria:  I class of obesity (BMI: 30-35 Kg/m2)  Exclusion Criteria:  evidence of heart, kidney or liver disease diagnosis of major depressive disorder current medications for weight loss, for control of cholesterol and triglycerides anti-inflammatory treatments pregrancy of lactation type 1 diabetes mellitus, intestinal inflammatory bowel disease, celiac disease, chronic pancreatitis probiotic/prebiotic treatment in the last 4 weeks antibiotic use within the last 3 months