Inclusion Criteria：  Patients with end-stage liver failure undergoing living-donor liver transplantation.  Subjects who are healthy physically and psychologically and willing to donate organs voluntarily.  Relative within the second degree of relationship or partner. (Acceptable degree conforms eligibility criteria of the institution.)  Exclusion Criteria：  Patients who have clinical findings of active infection.  Patients with advanced heart disease, fulminant hepatitis in liver failure, renal disease, malignant tumors and complications of immunodeficiency.