Inclusion Criteria:  Suspected SARS-CoV-2 infection as determined by treating clinical provider, or confirmed SARS-CoV-2 infection confirmed virologically in the lab by RT-PCR via nasopharyngeal or oropharyngeal sample or by SARS-CoV-2 Ag-RDTs that meet the minimum performance requirements of ≥80% sensitivity and ≥97% specificity compared to a NAAT reference assay. Receiving supplemental oxygen or showing clinical evidence of need for supplemental respiratory support as reflected in a respiratory rate ≥30 breaths per minute or an SpO2 ≤ 90%, SpO2 < 94 % if any emergency signs are present Admitted to health care facility  Exclusion Criteria:  Is not receiving oxygen or does not have clinical criteria for oxygen treatment specified above oxygen therapy Does not have suspected or confirmed COVID-19 (as per criteria above) Patient younger than 12 years of age Lack of commitment to full supportive care