Inclusion Criteria:  Patients who had not responded to any of the previously used pharmacological and non-pharmacological treatments. Literate and able to complete the questionnaires and scales used in the study. Patients who accepted their inclusion in the trial signed the corresponding informed consent and were given an explanatory sheet of the project.  Exclusion Criteria:  Patients with CNS involvement with or without treatment (stroke, Parkinson's, dementia, multiple sclerosis, etc.). Patients with inflammatory or autoimmune disease associated with Fibromyalgia. Patients with infectious, neoplastic disease, or parenteral drug use. Patients with insurmountable fear of needles Under 18 years of age Coagulation problems (including treatment with anticoagulants, due to the risk of bleeding). Immunosuppressed people (due to the risk of infection), Lymphadenectomized people (due to the risk of lymphedema) Hypothyroidism (due to the risk of myxedema) Pregnant patients Patients with areas of the skin that present some type of wound, infection, macula or tattoo.