Inclusion Criteria:  Age of 20 and older adult patients. preoperatively clinical and ultrasound assessment of the arm vessels are visible for the creation of a native HDAVF that include：the augmented diameters of the veins is > 2.0 mm and the diameter of the radial artery is> 2.0 mm. Besides, there is no obvious stenosis of vessels in the forearm.  Exclusion Criteria:  The patient refused to join the study serious heart failure (Physicians identify insufficient cardiac output that may affect sacral blood flow development after surgery) Unconsciousness Bedridden for long time systemic lupus erythematosus(SLE), or other known autoimmune diseases The physician excludes the possibility of creating a wrist HDAVF before surgery Surgeon preoperatively identifies vessel inadequacy for the creation of a wrist HDAVF Choose a site other than the wrist for surgery Unexpected complications happen during the surgery that prevent the completion of a wrist HDAVF