Inclusion Criteria:  all have a clear history of exposure to oral diquat solution; complete the toxicant test immediately after admission, and have certain initial blood drug concentration data; the clinical data is true and complete; the patients or family members are aware of and agree to the treatment plan.  Exclusion Criteria:  ingested two or more toxicants; diquat was not detected in the blood or urine and the patient has no relevant clinical symptoms; suffer from primary disease relative to heart, lung, liver, kidney and brain .