Key Inclusion Criteria:  Male or female between the ages of 18 and 60 (inclusive) at screening With a body mass index (BMI) between 18 kg/m2 and 30 kg/m2 (inclusive) at screening Healthy as determined at screening and on Day -1 Female subjects shall not be pregnant or breastfeeding Male partners of female subjects must also adopt a contraceptive method from screening through 5 months after administration of the investigational drug Able to understand and comply with the study procedures, understand the risks involved in this study, and provide written informed consent according to local and institutional guidelines before screening procedure  Key Exclusion Criteria:  History of clinically significant arrhythmia History of any type of malignant tumors within 5 years of the Screening Visit Positive serologic tests at screening for infections with human immunodeficiency virus (HIV) antibody, hepatitis C virus (HCV) antibody or hepatitis B virus (HBV) surface antigen at screening The vital signs of screening period and Day -1 were unqualified Subjects who have taken prescription medications within 28 days prior to screening or within 5 times of T1/2 (if known), whichever is longer History or evidence of any other clinically significant abnormalities, conditions, or diseases that, in the opinion of the investigator, would pose a risk to the safety of the subject or interfere with study evaluation, procedures, or its completion Any condition or treatment for a condition that might interfere with the conduct of the trial or might, in the opinion of the investigator, put the subject at risk, including but not limited to, alcoholism, drug dependence or abuse, and psychiatric conditions, if he/she participates in this study Positive test for alcohol or drug abuse at screening and on Day -1 Use of tobacco within 28 days prior to screening Hypersensitivity to mavacamten or any of the components of its formulation Prior exposure to mavacamten Unable to comply with the study restrictions/requirements, including the number of required visits to the clinical site Unsuitable to participate in the study as judged by the investigator