Inclusion Criteria:  Postmenopausal women veterans within 5 years of menopause.  Menopause is defined as:  women with intact uterus and last menstrual period >1 year ago but <5 years ago Age 50-60 years BMI 27-34.9kg/m2 (Overweight and low risk Class 1 Obesity) Symptomatic (moderate to severe vasomotor symptoms) Fasting glucose 100-150mg/dl or/or HbA1c >5.7%- and <7% (two abnormal test can be fasting glucose or HbA1c or combination of the two in the past 6 months). Triglycerides < 200 mg/dl GFR >60mL/min Normal mammogram within the past 12 months  Exclusion Criteria:  Amenorrhea from other causes (Hyperandrogenemia and anovulation) Recent weight change (>10 lbs in the last 3 months), intended or unintended Vulnerable populations (employees, students, individuals with impaired decision making capacity, pregnant women, prisoners, terminally ill, and children) Change in lipid lowering agent in the last 3 months Use of glucose lowering agents in the last 3 months Concurrent conditions including HIV, uncontrolled hyperthyroidism, uncontrolled hypothyroidism or less than 3 months since addition or change in thyroid hormone modulating medications, current use of drugs known to promote significant weight changes, menopause hormone therapy use within 3 months Contraindications to estrogens (history of thromboembolic disorder, coronary artery or cerebrovascular disease, clotting disorders (Antiphospholipid antibody syndrome, protein C deficiency, protein S deficiency, AT III deficiency, factor V leiden), severe liver disease, history of breast or uterine cancer or unexplained vaginal bleeding) Plan for major surgery or prolonged immobilization within 6 month period MRI Absolute contraindications