Inclusion Criteria:  Diagnosis of chronic subdural hematoma (CSDH) Written informed consent (patient, power of attorney or substitute decision maker) Competence to take study medication properly and regularly or access to caregiver that is able to comply with accurate study medication administration  Exclusion Criteria:  Hypersensitivity to TXA or any of the ingredients Pregnancy Irregular menstrual bleeding with unidentified cause Acquired colour vision disturbances Acute and chronic renal insufficiency indicated by GFR ≤ 30 mL/min Hematuria, caused by diseases of renal parenchyma Concomitant intake of hormonal contraceptives, factor IX complex concentrates, and anti-inhibitor coagulant concentrates (factor VII, activated factor IX) History of angioplasty with cardiac stent placement, or cardiac (including mechanical) valve placement Active history of stroke (hemorrhagic and ischemic), or subarachnoid hemorrhage, within the past 6 months Consumption coagulopathy/disseminated intravascular coagulation (DIC) in the last 7 days History of malignant brain tumors (glioma, metastasis and others) or seizures within the 6 months Contraindication to stopping full therapeutic doses of non-ASA antiplatelets, warfarin, rivaroxaban, apixaban, dabigatran, or other anticoagulant for 2 weeks after surgery Inability of oral drug intake or missing support to guarantee oral drug intake SDH as caused by intracranial hypotension resulting from CSF shunt placement