Inclusion Criteria:  Healthy male/female (based on medical history provided during a general health questionnaire) Age between 40 - 65 yrs Overweight (BMI ≥25 to ≤29.9 kg/m2) Sedentary subjects (Low Level [<600 MET-minutes/week] as assessed by the Physical Activity Questionnaire (IPAQ))  Exclusion Criteria:  Allergy to test product/control or citrus fruits and pomegranate Medical conditions that might interfere with endpoints or compromise participant safety during testing (e.g. Cardiovascular diseases, cancer, Parkinson's disease, Gastrointestinal diseases or abdominal surgery) to be decided by the principal investigator Use of medication that might interfere with endpoints (i.e.: β-blockers, antioxidant, antidepressants) High fasting blood glucose (FBG ≥100 mg/dL) Recent skeletal muscle injury in less than one month before the start of the study Use of antibiotics within 3 months prior to Visit 2 Use of probiotics or supplements containing vitamins, minerals or antioxidants four weeks prior to Visit 2 Regular smoking (including use of e-cigarettes) Inability to correctly perform the PA test during screening/familiarization Abuse of alcohol (alcohol consumption >20 units/week) and/or drugs Plans to change diet or medication for the duration of the study Treatment with an investigational drug (phase 1-3) 180 days before the start of the study Inability to understand study information and/or communicate with staff