Key Inclusion Criteria:  Women of non-childbearing potential and men either with a vasectomy, using contraception, or having sex with a woman of non-childbearing potential Body mass index (BMI) ≥ 18 kg/m2 and ≤ 32 kg/m2 Considered to be in good health Nonsmoker  Key Exclusion Criteria:  History or presence of any condition or prior surgery that, in the opinion of the investigator, poses a significant risk to subject safety and/or achievement of study objectives