Inclusion Criteria:  Idiopathic infertile men have had at least one year of unprotected intercourse infertility Sperm parameters abnormality  Exclusion Criteria:  Men with varicocele Hypersensitivity to pentoxifylline & zinc, pelvic organic pathologies congenital adrenal hyperplasia thyroid dysfunction Cushing's syndrome hyper prolactinemia androgen secreting neoplasia diabetes mellitus consumption of medications affecting carbohydrate metabolism severe hepatic pancreatitis kidney diseases gallbladder diseases Patients with alcohol consumption Patients who use cigarettes and drugs