Inclusion Criteria:  Acute myeloid leukemia chemo-induced febrile neutropenia Bloodstream infection  Exclusion Criteria:  lack of data endovascular infections surgical treatment required central nervous system infections antibiotic treatment < 4 days death before the end of antibiotic treatment unappropriated antibiotic treatment at 48h relapses of bloodstream infection episodes already included hematopoietic stem cell transplant