Inclusion Criteria:  Patients aged 18 to 90 years. Ability to understand and sign informed consent. Treatment infection responsive to Cefepime, Meropenem or Piperacillin / Tazobactam, Vancomycin. Absence of allergies to Cefepime, Meropenem or Piperacillin / Tazobactam, Vancomycin. Evidence of clinical response to treatment with Cefepime, Meropenem or Piperacillin / Tazobactam, Vancomycin and at least 3 days of apyrexia with current infusion antibiotic therapy. Good tolerance to ongoing antibiotic treatment with Cefepime, Meropenem or Piperacillin / Tazobactam, Vancomycin.  Exclusion Criteria:  Inability for any reason (e.g. absence of caregiver) to manage the elastomeric pump and access the hospital on a daily basis. Lack of adequate venous access. Inability to hydrate themselves properly orally. Infection involving the central nervous system. Creatinine> 2 mg / dL. Neutrophil granulocytes ≤ 1000 / µL. Platelets ≤ 20000 / µL. "aspartate amino transferase" and "alanine amino transferase" > 100 U / L. Bilirubin> 3 mg / dL. Presence of any comorbidities that, in the opinion of the physician, could compromise the safe execution of antibiotic home continuous infusion.