Inclusion Criteria:  Inpatients with 7 categories of diseases (including digestive system, respiratory system, cardiovascular and endocrine system, tumor, nervous system, and urinary system) Age ≥ 18 24～48h after admission  Exclusion Criteria:  Age<18 Critically ill patient With mental illness and cannot think or behavior normally Any other serious or uncontrolled illness which the investigator think is undesirable for the patient to enter the trial