Inclusion Criteria:  >= 18 years of age Histologically confirmed adenocarcinoma of the breast operable stage I-III or histologically confirmed carcinoma of the lung operable stage I-III will be enrolled prior to their definitive surgery Patients must have adequate organ function Patients must be willing to provide tissue, blood and stool samples for the research study  Exclusion Criteria:  Patients must not receive systemic neoadjuvant therapy Patients must not have taken any probiotics in the past 30 days prior to the enrollment Patients with autoimmune disease, immune deficiency such as human immunodeficiency virus (HIV), irritable bowel, known diverticulosis, and other serious gastrointestinal (GI) conditions at treating physician's discretion will be excluded