Inclusion Criteria:  Adult patients Ability to understand the purpose of the study, provide signed and dated informed consent by patient or his/her legal representative In-patients with acute tuberculosis, suspected tuberculosis or other pulmonary diseases (pneumonia, Bronchitis, COPD)  Inclusion criteria Healthy Donors:  negative for Quantiferon- TB Gold Plus Test or ELISpot  Exclusion Criteria:  Written rejection of the consent for the further use of the data