Inclusion Criteria:  Age >21 or <40 ASA physical status = 1 (normal healthy patient without systematic diseases or conditions) Metabolic Equivalents of Functional Capacity (METs) > 5 Low risk for Obstructive Sleep Apnea (OSA) based on the screening test (STOP-bang score established by American Society of Sleep Apnea): Yes to < 3 items- high risk of OSA No history Arrhythmia, such as heart block (Baseline EKG will be obtained during the history and physical session), seizure, liver and kidney diseases BMI <30 kg/m2 No history of any mental illness No history of drugs or alcohol abuse (an urine drug screen test required)  Exclusion Criteria:  Age <21 or >40 ASA physical status > 1 (normal healthy patient with systematic diseases or conditions) Metabolic Equivalents of Functional Capacity (METs)<5 High risks for Obstructive Sleep Apnea (OSA) based on the screening test (STOP-bang score established by American Society of Sleep Apnea): Yes to > 3 items- high risk of OSA History Arrhythmia (Baseline EKG will be obtained during the history and physical session), seizure, liver and kidney diseases BMI >30 kg/m2 History of any mental illness History of drugs or alcohol abuse (an urine drug screen test required) Female subjects with positive urine pregnancy test, which will be performed before each sedation session