Inclusion Criteria:  hospitalization for first myocardial infarction (STEMI or NSTEMI) age between 18 and 80  Exclusion Criteria:  uncompensated T2DM (HbA1c >53mmol/mol) use of anti-CD20 treatment chronic anti-inflammatory treatment for autoimmune disease (i.e. DMARDs, high dose FANS, cortisonic drugs)