Procurement Inclusion Criteria:  Any pediatric patient (age ≥ 1 year and ≤ 21 years), regardless of sex, with a diagnosis of Hodgkin or non-Hodgkin Lymphoma. Patients with life expectancy > 6 weeks. Hgb ≥ 7.0 (transfusions allowed). Informed Consent explained to, understood by and signed by patient/guardian. Patient/guardian given copy of informed consent. If applicable, patient assents to procurement,  Procurement Exclusion Criteria:  Patients with severe intercurrent infection. Patients with active HIV, Hepatitis B, or Hepatitis C infection at time of procurement (can be pending at the time of blood draw). Patients receiving systemic corticosteroids at the time of or within one week prior to procurement. Presence of grade 2-4 acute GVHD or active chronic GVHD > mild global severity score.  Treatment Inclusion Criteria:  Any pediatric patient (age ≥ 1 year and ≤ 21 years), regardless of sex, with a diagnosis of Hodgkin or non-Hodgkin Lymphoma who are in complete remission (CR), but at high risk for relapse (specifically, who are stage 3 or stage 4 at diagnosis, are in second complete remission (CR2), and who have previously received >2 lines of lymphoma-directed therapy). Patients with life expectancy > 6 weeks. Pulse oximetry of > 90% on room air in patients who previously received radiation therapy. Patients with a Karnofsky/Lansky score of > 60 Patients with bilirubin < 3x upper limit of normal Patients with a creatinine ≤ 2x upper limit of normal for age. Patients with AST < 3x upper limit of normal. Patients with Hgb ≥ 7.0 (transfusions allowed) Acceptable organ function based on clinical or laboratory findings according to investigator discretion Patients should have been off other investigational therapy for one month prior to entry in this study. Patients should have been off conventional therapy including rituximab for at least 1 week prior to entry in this study, and at least 4 weeks since last dose of radiation (if applicable) Informed Consent explained to, understood by and signed by patient/guardian. Patient/guardian given copy of informed consent. If applicable, patient assents to participation in trial. Due to unknown effects of this therapy on a fetus, pregnant women are excluded from this research. The male partner should use a condom. Females of child-bearing potential must be willing to utilize one of the more effective birth control methods during the study unless female has had a hysterectomy or tubal ligation  Treatment Exclusion Criteria:  Patients with severe intercurrent infection. Presence of grade 2-4 acute GVHD or active chronic GVHD > mild global severity score. Patients receiving systemic corticosteroids > 0.5mg/kg prednisone or equivalent. Pregnant or breastfeeding. Active viral infection with HIV or hepatitis type B or C. "Active" infection defined as infectious disease testing indicating that patient blood is reactive for Hep B, C and/or HIV and confirmed using PCR to measure viral load.