Inclusion Criteria:  Adult patients (18 years or older). Patients with septic shock Patients with a SOFA > 4 points.  5. Oxygen saturation in the central venous system > 70% 5. Central venous pressure> 8 mmHg. 6. Signature of the informed consent by the patient or her legal representative.  Exclusion Criteria:  Pregnant or lactating patients. Pathologies in which terlipressin is clinically indicated: gastrointestinal bleeding due to esophageal-gastric varices, hepatorenal syndrome. Patients diagnosed with unstable acute coronary syndrome. Patients with acute or chronic mesenteric ischemia. Patients with Raynaud's Phenomenon, or vasospastic disease. Patients participating in another intervention clinical trial. Patients with active bleeding. Patients with renal replacement technique at the time of randomization. Patients with some limitation of life support treatment Previous use of terlipressin during your stay in the intensive Care Unit