Inclusion Criteria:  Children ≥ 5 years to < 16 years of age Receiving an authorized or approved and recommended COVID-19 vaccine per standard of care Parent/legal authorized representative (LAR) willing to provide written or electronic informed consent per local IRB requirements Participant willing to provide assent per local IRB requirements Intention of being available for entire study period and complete all relevant study procedures, including follow-up phone calls English or Spanish literate.  Exclusion Criteria:  Participation in a COVID-19 vaccine interventional trial Any condition, which, in the opinion of the investigators, may pose a health risk to the subject or interfere with the evaluation of the study objectives. Anyone who is a relative of any research study personnel.