Inclusion Criteria:  Confirmed diagnosis of Type II Diabetes Mellitus patients who have been on anti-diabetic therapy for 1 year or more Diabetic patient who meet the clinical criteria for DPN diagnosed by an endocrinologist of OPD of endocrinology Age between 18 and 70 years Gender: Both Male and Female Patients who will give informed written consent  Exclusion Criteria:  Patients suffering from other causes of peripheral neuropathy for example chemotherapy-induced neuropathy, hyperthyroidism or hypothyroidism, rheumatoid arthritis, SLE Pregnant or lactating women Patients with renal and liver disease, psychiatric disorder Patients receiving vitamin D, vitamin B6, vitamin B12 supplementation, anticonvulsants, antidepressants, opioids, and other neuropathic pain medications within the last two months. Serum calcium level: > 10.2 mg/dl HbA1c level > 11% Serum creatinine level > 1.4 mg/dl