Inclusion Criteria:  Woman aged between 18 and 55 With a diagnosis of invasive breast carcinoma of stage cTNM or pTNM I to III (UICC 8th edition), confirmed by histological examination Treated by intravenous cytotoxic chemotherapy in an adjuvant or neoadjuvant situation Breast surgery +/- of the axillary area, carried out within 3 months preceding the start of adjuvant chemotherapy, or scheduled after neo-adjuvant chemotherapy +/- radiotherapy. In salaried employment at the time of diagnosis (permanent or temporary contract, interim assignment, civil servant) Affiliated to a French social security scheme Reading, understanding and writing the French language Followed in one of the investigating centers Not opposing the collection of data  Exclusion Criteria:  In situ carcinoma Distant metastases History or co-existence of another primary cancer (apart from a basal cell cancer of the skin and / or a non-mammary cancer in complete remission for more than 5 years) Recurrence or second breast cancer Without employment contract; self-employed or supported contract Cannot be followed for the duration of the study, for medical, social, family, geographic or psychological reasons Deprived of liberty by court or administrative decision