Inclusion Criteria:  Individuals who tested positive for SARS-CoV-2 in March 2020. These patients will be divided into two groups and followed up over time. The first group will include patients who have recovered and have not received the vaccine. The second group will include patients who have recovered and have received the vaccine. No acute respiratory infection or active SARS-CoV-2 infection. Informed consent of the adult participant.  Exclusion Criteria:  Individuals <18 years or >80 years. No informed consent by the adult participant. Suspicion of acute COVID-19 infection