Inclusion Criteria:  Presence of knee pain Kellgren-Lawrence (KL) grade 1-3 assessed by weight-bearing knee radiographs Local tenderness around the knee Clinical failure after 3 months or more of conservative therapies, including oral nonsteroidal anti-inflammatory drugs and/or oral opioid agents and physical therapy, stretching, muscle strengthening and/or intra-articular injection of hyaluronic acid Persistent moderate to severe knee pain (VAS > 50 mm) for more than 3 months Patient is able to give consent  Exclusion Criteria:  Previous knee surgery Local infection BMI > 40 kg/m2 Advanced atherosclerosis Rheumatoid arthritis, malignancy, renal insufficiency, other conditions contra-indicating femoropopliteal angiography Usage of anticoagulants such as eliquis or coumarine (Asaflow allowed) Allergy to iodinated contrast medium or any other allergy