Inclusion Criteria:  All adult (≥ 18 years old) patients with a non-metastatic (based on NCCN definition) on imaging pancreatic tumour of the head or uncinate process treated with a pancreaticoduodenectomy  Exclusion Criteria:  All paediatric patients (< 18 years old) Patients that cannot provide consent All borderline, locally advanced and metastatic pancreatic tumours on imaging (based on NCCN criteria) All patients with a cytological or histological diagnosis of cholangiocarcinoma, ampullary and duodenal carcinoma All patients with benign disease or dysplasia with no evidence of malignancy