Inclusion Criteria:  Patient ≥ 18 years old, Patient to be operated in first intention of a sleeve gastrectomy Initial BMI between 35Kg/m² and 40 Kg/m² associated with an obesity-related comorbidity (hypertension, obstructive sleep apnea syndrome, type II diabetes, early osteoarthritis authenticated by a rheumatologist or an orthopedist, dyslipidemia, hepatic steatosis) OR initial BMI ≥ 40 Kg/m². Multidisciplinary follow-up of at least 6 months before surgery Validation of the surgical intervention in a multidisciplinary consultation meeting Certificate of no contraindication by a psychiatrist Patient who has the capacity to understand the protocol and has given consent to participate in the research, Patient with social security coverage.  Exclusion Criteria:  Eating disorder or mental disorder Misunderstanding of the protocol Psychiatric contraindication Initial BMI <35Kg/m². Initial BMI between 35Kg/m² and 40 Kg/m² without comorbidities. Esophagitis of grade B and above on the Oeso-Gastro-Duodenal Fibroscopy CARLSSON score (score ≥ 4) preoperatively Presence of a Proton-Pump Inhibitors treatment Patient to have a 2-stage surgery (first sleeve gastrectomy then gastric bypass or Single Anastomosis Duodeno-Ileal bypass) Patient participating in another interventional clinical research protocol involving a drug or medical device Patient who are pregnant, breastfeeding, or who have the potential to become pregnant without effective contraception at the time of inclusion and up to 24 months after surgery Patient under guardianship, curators or legal protection,P