Inclusion Criteria:  Healthy subject. Sex: female or male. Age: between 30 and 65 years. Subject having given freely and expressly his/her informed consent and data privacy consent. Subject with approximate symmetry, moderate to severe Nasolabial Folds (NLFs) attaining either grade 3 on both sides or grade 4 on both sides on the Wrinkle Severity Rating Scale (WSRS) for NLF, as assessed in live. Subject with marionette's lines that do not require to be treated according to investigator. Subject willing to have photographs of the face taken. Subject, psychologically able to understand the study related information and to give a written informed consent. Subject agreeing not to receive another aesthetic procedure on the face (e.g., laser, dermabrasion, surgery, deep chemical peeling, surface peel, tensor threads, injection with a filling product) during the whole study. Subject affiliated to a health social security system. Female of childbearing potential should use a medically accepted contraceptive regimen since at least 12 weeks before screening visit and during the whole study.  Exclusion Criteria:  Pregnant or breastfeeding woman or planning a pregnancy during the study. Subject with a tattoo, a scar, moles or anything on the studied zones which might interfere with the evaluation. Subject who had been deprived of their freedom by administrative or legal decision or who is under guardianship. Subject in a social or sanitary establishment. Subject participating to another research on human beings or who is in an exclusion period of one. For France only: subject having received 4500 euros indemnities for participation in researches involving human beings in France in the 12 previous months, including participation in the present study. Subject suffering from a severe or progressive disease or any other pathology that may interfere with the evaluation of the study results. Subject suffering from untreated epilepsy. Subject with known history of or suffering from autoimmune disease and/or immune deficiency. Subject with a past history of streptococcal disease, such as acute rheumatic fever or recurrent sore throats and in case of acute rheumatic fever with heart complications. Subjects suffering from porphyria. Subject suffering from inflammatory and/or infectious cutaneous disorders in or near the studied zones (herpes, acne, mycosis, papilloma…). Subject with recurrent herpes is not eligible even if asymptomatic at time of screening visit. Subject having history of allergy or anaphylactic shock including hypersensitivity to hyaluronic acid, to gram positive bacterial proteins, to lidocaine, to one of the components of the tested devices or antiseptic solution or amide-type local anaesthetics. Subject having history of severe and/or evolutive / unstable / recent allergy. Subject predisposed to develop keloids or hypertrophic scarring. Subject prone to develop inflammatory skin conditions or having tendency to bleeding disorders. Subjects with known cardiac conduction disorders. Subject having received treatment with a laser, a dermabrasion, a surgery, a deep chemical peeling or other ablative procedure below the inferior orbital rim within the past 12 months prior to screening visit. Subject having received treatment with a surface peel below the inferior orbital rim within the past 6 months prior to screening visit. Subject having received injection with a resorbable filling product (eg, hyaluronic acid, collagen) below the inferior orbital rim within the past 12 months prior to screening visit. Subject having received at any time injection with a slowly resorbable filling product (polylactic acid, calcium hydroxyapatite, combinations of hyaluronic acid (HA) and hypromellose, HA and dextran microbeads or HA and TriCalcium Phosphate (TCP), …) or with a non-resorbable permanent filling product (polyacrylamide, silicone, combination of methacrylic polymers and collagen, polymer particles, …). Subject having received at any time a treatment with tensor threads below the inferior orbital rim. Subject who received oral surgery (e.g. tooth extraction, orthodontia or implantation) within 6 weeks prior to screening visit or who plans to undergo any of these procedures during the study. Subject having started or changed her oral contraceptive or any other hormonal treatment during 12 weeks prior to screening visit. Subject using medication such as aspirin, nonsteroidal anti-inflammatory drugs (NSAID) (ibuprofène, naproxène, …), antiplatelet agents, anticoagulants, vitamin C or other substances known to prolong bleeding time (warfarin, , herbal supplements with garlic or ginkgo biloba, …) within 1 week prior to injection visit (V1) and agreeing not to take such treatments within 1 week prior to touch-up visit, or being a chronic user. Subject using medication that reduce or inhibit hepatic metabolism (cimetidine, beta-blockers, etc). Total injection volume of cross-linked hyaluronic acid >14 mL within 1 year prior to screening visit.  Subject undergoing a topical treatment on the test area or a systemic treatment:  Anti-histamines during the 2 weeks prior to injection visit (V1) and agreeing not to take such treatment within 2 weeks prior to touch-up visit; Immunosuppressors and/or corticoids during the 4 weeks prior to screening visit; Retinoids during the 6 months prior to screening visit.