Inclusion Criteria:  Subjects of age between ≥ 60 through ≤ 85 years. Subjects show signs of frailty condition as assessed by the Investigator with a Clinical Frailty scale between 4 to 6. Subjects with body weight between 40 to 90 kg. Subject is willing to provide written informed consent to participate in the study after reading the informed consent form and the information provided.  Exclusion Criteria:  Subjects unwilling or unable to perform any of the assessments required by endpoint analysis. Subjects who have a diagnosis of any disabling neurologic disorder including, but not limited to: Parkinson's disease, Amyotrophic Lateral Sclerosis, multiple sclerosis, stroke or dementia. Subjects have a score on the Mini-Mental State Examination (MMSE) of 24 or below.  Subjects who have a significant comorbid medical condition(s) including, but not limited to:  Severe kidney disease requiring hemodialysis or peritoneal dialysis; Advanced liver disease such as hepatitis or liver cirrhosis; Severe congestive heart failure (NYHA class 3 and 4); Severe pulmonary dysfunction, including severe chronic obstructive pulmonary disease stage III or IV (Gold classification) Hypothyroidism (TSH > 10 mU/L) or hyperthyroidism (TSH < 0.1 mU/L) Subjects who have autoimmune disease including, but not limited to: rheumatoid arthritis, systemic lupus erythematosus. Subjects on chronic immunosuppressive transplant therapy. Subjects who have a clinical history of malignancy within 5 years (i.e., patients with prior malignancy must be disease free for 5 years), except curatively-treated basal cell carcinoma or in situ carcinomas. Subjects using chronic immunosuppressant therapy or TNF-alpha antagonists. Subjects who are known to be infected with HIV. Subjects with known allergy or hypersensitivity to any component of the formulation, including normal saline, human serum albumin, dimethyl sulfoxide (DMSO) and cellular therapies. Subjects who have participated in another clinical study of new investigational therapies within 6 months before the study drug administration. Subjects have a history of drug or alcohol abuse within the past 3 years. Subjects currently in hospital stay. Any other condition that, in the opinion of the investigator, may compromise the safety or compliance of the patient or preclude successful completion of the study.  Subjects with uncorrected hematology test including, but not limited to:  Hemoglobin < 8 g/dl White blood cell count < 3,000/mm3 International normalized ratio (INR) of Coagulopathy >1.5 Platelet count < 80,000/mm3  Subjects who have the following conditions in laboratory tests:  >2 × upper limit of normal for alanine aminotransferase (ALT) or aspartate aminotransferase (AST) Total bilirubin > 1.5 mg/dl  Subjects who have a significant illness as judged by principal investigator (PI) including, but not limited to:  Psychiatric illness Uncontrolled hypertension or hypotension (specify numeric cutoffs) Unstable cardiac arrhythmia Severe osteoarthritis or degenerative joint disease Hepatitis B, Hepatitis C infections History of recent or ongoing COVID-19 Have any condition that in the opinion of the Principal Investigator limits lifespan to < 1 year.