Inclusion Criteria:  Male or female, adults or children with permanent teeth (immature or mature) Treated with an endodontic microsurgery using Biodentine™: all microsurgery including root end-filling, external or internal root resorption repair, root and furcation perforation repair and apexification Patients treated between 01 March 2016 and 30 September 2020 Availability of baseline radiographic images Patients affiliated to national health insurance Patients informed about the study and who consent to participate to the study  Exclusion Criteria:  Patients treated with anti-cancer therapy in the 5 years prior to the treatment Uncontrolled systemic disease 1 month prior to the treatment Development of a cancer or a systemic disease just after the treatment Participation to an interventional clinical trial at the time of the treatment