Inclusion Criteria:  Include participants with stage five of chronic kidney disease, People over 18 years old. Their participation is voluntary and their have signed the informed consent form. Persons that are undergoing hemodialysis for at least 3 months. Persons have ability to do exercise protocols. Persons have the approval by nephrologist doctor and deportologist for to do the study according to the results of initial medical assessment.  Exclusion Criteria:  Surgical intervention to least 6 months. Skeletal limitations that affect exercise performance. Psychiatric disorders and psychological such as depression, anxiety that could be affect participation of the study. Body Mass Index greater than 30 kg/m2 and not less than 18.5 kg/m2. Hemodialysis catheter dysfunction or infection as well as participation in home exercise programs.