Inclusion Criteria:  Patients aged>18 years old ASA I-III Patients scheduled for elective transurethral urologic surgery with general anesthesia  Exclusion Criteria:  • Patient refusal  Use of opioids pre-op Inability to read or write Known psychiatric disease under medication Dementia Severe liver and renal disease Known allergy to drugs used Known arrhythmia (2nd-3rd AV block, acute unstable angina, acute myocardial infarction in the past 6 weeks or severe cardiac problem-condition) Heart rate<45 bpm Pre-op minimental test<23 Major surgery complications (hemorrhage with need for transfusion)