Key Inclusion Criteria:  Able to understand and sign an Institutional Review Board (IRB)/Independent Ethics Committee (IEC) approved informed consent form. Willing and able to attend all study visits as required per protocol. Have dry eye symptoms as specified in the protocol. Willing to discontinue use of all habitual artificial tear supplements for the entire study duration. Other protocol-defined inclusion criteria may apply.  Key Exclusion Criteria:  Ocular conditions as specified in the protocol. Contact lens use within one week prior to screening visit. Use of medications as specified in the protocol. Pregnant or breast feeding. Other protocol-defined exclusion criteria may apply.