Inclusion Criteria:  10 to 78 years of age. Medical history meets the criteria for the International Classification of Diseases diagnosis codes 10 (ICD-10) for cerebral cavernous malformations (CCMs) (Q28.3) or stroke/epilepsy. Has a family member whose medical history meets the criteria for the International Classification of Diseases diagnosis codes for cerebral cavernous malformations (CCMs) (Q28.3) or stroke/epilepsy. Has a relatively complete medical history that can be accurately confirmed by an interview or electronic and/or paper medical records. Hispanic and non-Hispanic Americans.  Exclusion Criteria:  N/A