Inclusion Criteria:  All locations of primitives (intrahepatic CCA, extrahepatic CCA, adenocarcinoma of the gallbladder; ampullomas excluded) Age > 18 years Diagnosed between 2003 and 2030 (minimum follow-up 2 years) Written written non-opposition +/- signed informed consent for genetic studies (N.B.:  exemption requested for a deceased patient) N.B. Authorized inclusion in a therapeutic research protocol  Exclusion Criteria:  Patient under guardianship, curatorship or legal protection Pregnant or breastfeeding women Any medical, psychological or social situation, which could prevent the compliance with the protocol according to the investigator's assessment Refusal to participate in the study