Inclusion Criteria:  South Korean adult.  With constipation caused by:  Chronic Idiopathic Constipation (CIC), or Opioid-Induced Constipation (OIC) from treatment for chronic, non-cancer pain, including participants with chronic pain related to prior cancer or its treatment who do not require frequent (example weekly) opioid dosage escalation. Is newly prescribed (first incident) and initiates lubiprostone for the treatment of constipation.  Exclusion Criteria:  Treated with lubiprostone outside of the locally approved label in South Korea. Participating in any other clinical study investigating one (or more) of the approved indications of lubiprostone.