Inclusion Criteria:  Participants have completed WE-MACNUTR trial in 2019 Participants have no traveling plans within 1 months Participants are able and willing to comply with the study protocol and provide informed consent  Exclusion Criteria:  Refuse or are unable to provide informed consent to participate in the study Have long-term gastrointestinal diseases and take daily relevant medications Have taken antibiotics in the last 2 weeks Have type 2 diabetes and are taking medications or other treatments Have chronic or acute liver disease and are taking medications or other treatments Have cardiovascular diseases and are taking medications or other treatments Have kidney disease and are taking medications Suffer from chronic anxiety or depression, or other critical neuronal disorder and/or history of relevant medication Are pregnant or lactating, or are planning to be pregnant in the next 3 months Diagnosed with an eating disorder (e.g. anorexia nervosa or bulimia nervosa) Are vegan, or unwilling to consume foods provided in the study Have history of alcohol or drug addiction, or smoke above 15 cigarettes per day