Inclusion Criteria:  At least 7 days of aspirin therapy (acetylsalicylic acid, 100 mg daily) prior to stroke onset Within 24 h of experiencing a new focal or global neurological deficit. Evidence of new or old ischemic infarct on CT brain or magnetic resonance imaging (MRI). With informed consents. Presence or not previous cerebrovascular event as previous history of transient ischemic attack (TIA) before the onset of stroke.  Exclusion Criteria:  Patients with other neurological deficits due to stroke mimics or hemorrhagic insult. Patients is subjected to anticoagulant treatment (atrial fibrillation, valve replacement, others).