Inclusion Criteria:  Female sex at birth Age at least 18 years at the time of invitation Eastern Cooperative Oncology Group (ECOG) Performance Status score of either 0 or 1 With histopathologic diagnosis of breast carcinoma Already completed prescribed mastectomy and chemotherapy (adjuvant or neoadjuvant) interventions Scheduled to receive hypo fractionated postmastectomy-postchemotherapy radiation therapy  Exclusion Criteria:  Pregnant or lactating With concurrent or previous history of any malignancy With history of mediastinal or thoracic irradiation With current bilateral synchronous breast carcinoma With diagnosis of metastases from any form of breast cancer With any skin lesion in the planned radiation field deemed deramtologically and/or radiotherapeutically relevant With concomitant disease states deemed clinically significant (connective tissue diseases, infections, uncontrolled chronic disorders, renal failure, hepatic dysfunction, etc.) With known history of hypersensitivities and/or reactions against any component of either experimental or comparator interventions Inability to personally provide informed consent or to personally comply with skin care instructions