Inclusion Criteria:  age ≥18 years; confirmed large vessel occlusion in the anterior circulation (intracranial internal carotid artery, M1segment of middle cerebral artery, proximal M2 segment of middle cerebral artery time from last seen well to treatment (TLSWT) <24 hours, baseline National Institutes of Health Stroke Scale (NIHSS) score ≥2, premorbid modified Rankin Scale (mRS) score ≤2.  Exclusion Criteria:  No evidence vessel occlusion. Extra and Intracranial occlusion or severe stenosis. Low platelets (100 x 10000) or impaired function, Contraindication of computed tomography or magnetic resonance Allergy to iodinated contrast non treatable medically, pregnant or breast feeding patient, hemorrhagic stroke on computed tomography or Magnetic Resonance