Inclusion Criteria:  Men and women Age ≥ 65 and ≤ 75 years Newly diagnosed patients with de novo or secondary AML in first complete remission who are considered as potential candidates and eligible for an allo-HSCT procedure Presence of a donor (matched related or unrelated or haplo-mismatched) willing to donate peripheral blood stem cells Patient is fit for the allo-HSCT procedure Patient is fit for further consolidation therapy (non-transplant arm) Written informed consent  Exclusion Criteria:  Acute promyelocytic leukemia (AML FAB M3) AML deemed not eligible for allo-HSCT Karnofsky score <70% HIV positive patient Life expectancy less than one month according to the attending physician Acute or chronic heart failure (Cardiac ejection fraction < 40%) Pulmonary function - diffusion capacity < 50% predicted Estimated glomerular filtration rate < 50 ml/min (CKD-EPI) Severe neurological disorders Patient subject to a legal protection measure (guardianship, curatorship and safeguard of justice) or unable to consent Patient deprived of their liberty by a judicial or administrative decision Patient with severe psychiatric disorders or hospitalized without consent for psychiatric care