Inclusion Criteria:  all patients with chronic wound chronic wound irrespective of the ethology (arterial, diabetic, venous, decubital, combined etiology, posttraumatic, postamputation, burn, and other) 18 years of age and older signed informed consent  Exclusion criteria:  • failure to meet one of the inclusion criteria  Exclusion criteria from HBOT group:  patients with absolute or relative contraindications for HBOT patients on bleomycin chemotherapy patients with chronic obstructive pulmonary disease, previous spontaneous pneumothorax, chronic otitis media or chronic sinusitis, unstable angina pectoris, severe heart failure, severe dementia, history of seizures, claustrophobia patients with significant macroangiopathy and absent both distal pulses and no positive response following oxygen provocation test on transcutaneous oximetry