Inclusion Criteria:  Eligible for Chemotherapy for the first time (Previous & Ongoing hormonal only treatment allowed OR Neoadjuvant & Adjuvant chemotherapy regimens with 2+ drugs allowed) > 18 years old Eastern Cooperative Oncology Group (ECOG) performance status 0-2. There are no life expectancy restrictions Women of child-bearing potential are allowed in the study as long as they are eligible for the chemotherapy treatment. Ability to understand and the willingness to sign a written informed consent document.  Exclusion Criteria:  Patients on immunotherapy only will be excluded Previous chemotherapy Under 18 years old Medically Diagnosed with a Cognitive Impairment. Rationale for excluding people with cognitive impairment is that they would not be able to fully participate in the self-management care aspects of the intervention via the telephone, nor provide informed consent. No access to a telephone Blind or Deaf; If subject is Hearing-impaired or illiterate, then the subject may have a family member participate as a telecommunication surrogate with them in the study