Inclusion Criteria:  Both genders above 18 years Wounds for more than 6 weeks History of trauma, tumor, congenital physical abnormalities Hemoglobin levels more than 10 g/dl Platelet count above 150 x 10E9/L Size of wound > 10*10cm.  Exclusion Criteria:  Pressure ulcers Co-morbidities like diabetes or hypertension Bleeding vessels Presence of Necrotic tissue Malignancy in wounds