Inclusion Criteria:  Documented diagnosis of primary kidney disease Regular visits (at least 6 monthly) with a physician at a participating site eGFR > 15 ml/min/1.73 m2 ≥ 2 years of age Willing and able to sign informed consent Willing to be approached about participation in interventional research studies  Exclusion Criteria:  1. Life-expectancy of less than 6 months