Inclusion Criteria:  Postnatal age < or = 28 days; cEEG monitoring at least 12hours monitoring; Suspected seizures; Risk of Intracranial hemorrhage; Abnormality of MRI or ultrasound before cEEG; Neonates diagnosed with encephalopathy or suspected of encephalopathy; Hypoxic-ischemic encephalopathy or suspected hypoxic-ischemic encephalopathy; Metabolic disturbances (Hypoglycemia, Hypocalcemia, Hypomagnesemia, Inborn errors of metabolism); Central nervous system (CNS) or systemic infections; Postsurgical neonatal within 3 days; Suspected genetic disease or Positive genetic diagnoses;  Exclusion Criteria:  The neonates with head scalp defect, scalp hematoma, edema and other contraindications which are not suitable for cEEG monitoring during hospitalization.