Inclusion Criteria:  patients previously diagnosed with hepatits c, with education, ability and willing to participate in the study  Exclusion Criteria:  Patients with systemic diseases such as nutritional deficiency; cardiovascular, respiratory, metabolic, and endocrinal disorders; also smoking and alcoholism that could affect their oral health status were excluded. As well as history of an intervention or condition that could affect the oral mucosa (e.g., history of radiotherapy).