Inclusion Criteria:  Age 18 Years to 80 Years Consecutive patients with preoperative pathologically confirmed AGC by endoscopy and preoperative imaging data (CT/MRI) were included. Clinical staging Ⅱ-Ⅲ according to the UICC/AJCC 8th guideline for gastric cancer without distant metastasis. Suitable for pre-operative chemotherapy, immunotherapy and surgical resection No contraindications for CT/MRI examination. Eastern Cooperative Oncology Group (ECOG) performance status 0-2. The patients participate in this study with informed consent.  Exclusion Criteria:  Patients with a history of previous chemotherapy or immunotherapy. The patients couldn't perform MSCT or MR scanning or artefacts affect the evaluation. The patients are extremely anxious and uncooperative about surgery or neoadjuvant therapy. The patients refuse to participate in the project. Pregnancy, lactation or inadequate contraception Pacemaker or implanted defibrillator Patients with a history of psychological illness or condition such as to interfere with the patient's ability to understand requirements of the study. Other situations considered by investigators, which not meet the inclusion criteria.