Inclusion Criteria:  X-linked hypophosphatemia diagnosed by the doctor specializing in the disease. Patients with at least two healthy contralateral quadrants (right and left) at inclusion defined by the absence of symptomatic or asymptomatic spontaneous abscess, carious lesion and trauma (concussion, subluxation, dislocation, crack, fracture) on all teeth in the quadrant.  Exclusion Criteria:  Antibiotic treatment within 15 days prior to inclusion Patients with a mental disability, Patients with cancer, heart disease, sickle cell anemia, pathological bruxism Patients with contraindications to study treatments