Inclusion Criteria:  Age ≥ 18 years Carrier of Tubiana stage II-IV Dupuytren's disease on at least one or more rays, not previously operated Indication of a surgery by aponeurectomy Skin pinch of the posterior aspect of the arm of more than 1cm Affiliation to a social security system Patient informed of the study and having given informed consent  Exclusion Criteria:  Previous surgery of any kind for Dupuytren's disease Involvement on the thumb only Need for a total skin graft or a pedicle flap on all the rays to be treated Active autoimmune disease Previous treatment with collagenase Pregnant and breastfeeding women Patient under legal protection Contraindications to MRI (criteria applicable only for patients from the coordinating center, not applicable for other centers)