Inclusion Criteria:  Age> 18 years The presence of morphological verification of squamous cell carcinoma of the head and neck No history of anticancer treatment ECOG score 0 - 2 Life expectancy is more than 3 months Normal liver, kidney and bone marrow function Absence of severe uncontrolled concomitant chronic diseases and acute diseases (including infectious diseases) Absence of pregnancy, lactation Initial compliance of patients (according to the consultation of a psychologist and questionnaires) with a signed informed consent  Exclusion Criteria:  Simultaneous participation in another clinical trial Failure to meet inclusion criteria The patient's condition is ECOG ≥3, Karnovsky ≤40%. Bleeding Decay / Abscess in the area of tumor lesion Pregnancy or breastfeeding Refractory cachexia Allergy or intolerance to any of the components of ONS