Inclusion Criteria:  18 - 50 years old Participant must be able to understand and perform informed consent.  IgE-mediated food allergy to at least one of the following foods as defined by (regarding at least one of the foods):  ° Foods: peanut, cashew, walnut, hazelnut, sesame, cod, and/or shrimp, history of an acute allergic reaction (urticaria, angioedema, cough, wheeze, and/or repetitive vomiting within an hour of ingestion, and history of positive skin or serum IgE test, and current strict avoidance of the food, and current possession of physician-prescribed self-injectable epinephrine, and skin test wheal 5 mm or greater average diameter  Atopic dermatitis (AD) diagnosis for at least 1 year with at least 7% current BSA involvement. If female of childbearing potential, must have a negative pregnancy test (serum or urine) and agree to abstinence or acceptable contraception. Plan to remain in the Tri-State area during the trial for visits. Must agree to avoid prolonged exposure to the sun and not to use tanning booths, sunlamps, or other ultraviolet (UV) light sources during the study. If receiving concomitant medications for any reason other than AD, must be on a stable regimen, which is defined as not starting a new drug or changing dosage within 7 days or 5 half-lives (whichever is longer) prior to Day 1 and through the duration of the study.  Exclusion Criteria:  Unwilling or unable to give written informed consent or comply with protocol. Unable to swallow pill. Use of dupilumab within 6 weeks of enrollment. Prior use or allergy to drugs related to abrocitinib (ruxolitinib, upadacitinib, etc). Use of any other biologic (monoclonal antibody) medication within 12 weeks or 5 half-lives of drug, if known. Allergy to any excipients within abrocitinib. Use of build-up environmental immunotherapy; any food oral immunotherapy;or systemic oral, IV or IM steroids including but not limited to- prednisone, methylprednisolone, prednisolone, solumedrol, solucortef, dexamethasone in the past 4 weeks or 5 half-lives of drug, if known. Use of CYP2C9 and CYP2C19 inducers (such as carbamazepine, norfluoxetine, etc.) within 5 half-lives of the inducer plus 14 days prior to the first dose of study intervention. Use of CYP2C9 and CYP2C19 inhibitors within 1 week of first dose of study intervention or within 5 half-lives (if known) of the inhibitor, whichever is longer. Unable to stop long-acting antihistamines within minimum wash out period required for SPTs at screening and site visits History of or significant risk factor(s) for cardiovascular disease