Inclusion Criteria:  Body weight ≥ 45 kg, 19 ≤ body mass index (BMI) ≤ 28 kg /m2; Women with sexual experience, potential fertility and regular menstrual cycle (25-34 days) (including boundary value); The levels of sex hormones were normal or abnormal without clinical significance at the time of screening; The physiological structure of uterus and bilateral ovaries was normal or abnormal by ultrasound examination, without clinical significance;  Exclusion Criteria:  Known the history of stage III / IV endometriosis, submucosal myoma and endocrine abnormality within 6 months before enrollment; Known the history of ovarian hyperstimulation syndrome (OHSS); Premature ovarian failure, decreased ovarian reserve function (Antral Follicle Counting < 3), high ovarian response, polycystic ovary syndrome, unexplained vaginal bleeding or endometrial hyperplasia; Any FSH or HMG preparations were used within 3 months before the first study; Pregnancy or lactating women.