Inclusion Criteria:  Registered Permanent residents or have lived for more than 5 years and have local social security medical insurance Patients with no serious physical disability and can communicate normally Patients who participate voluntarily and sign informed consent Patients whose diseases and deaths are managed by the local health department  Exclusion Criteria:  Temporary residents and floating population Patients with serious health conditions and cannot participate in the investigation Patients who are unwilling to accept follow-up inspections of the project