Inclusion Criteria:  Age between 18-50 years. Total burn surface area of 20% - 60%. Expected length of stay in ICU > 48 hr. Admission within 72 hrs of burn injury. Any thermal injury such as flame burns. Scald burns and contact burns.  Exclusion Criteria:  Burn patients with hepatic failure. Burn patient with Severe renal failure (glomerular filtration rate (eGFR <50 ml/min). Patients with inborn errors of amino-acid metabolism (e.g., phenylketonuria). Burn patients with pre-existing severe cardiac, pulmonary diseases. Burn patients with diabetes mellitus or cancer. Patients with metabolic acidosis (pH<7.35). Electric burns.