Inclusion Criteria:  Age more than or equal to 18 years of age Body Mass Index between 30 to 45 kg/m^2 Blood pressure: Systolic BP more than or equal to 140mmHg and less than or equal to 160 mmHg and diastolic blood pressure more than or equal to 80mmHg and less than or equal to 100mmHg.  Exclusion Criteria:  Age less than 18, at screening. Systolic BP <140 or >160 mm Hg at baseline, or diastolic BP <80 or >100 mm Hg at baseline. BMI <30 kg/m^2 or >45 kg/m^2; History of pulmonary hypertension. Have any past or present illness of cardiovascular disease including myocardial infarction, angina, cardiac arrhythmia, diabetes, stroke, TIA, or seizure. Participants who are taking more than 2 hypertension medications. History of angioedema; Estimated glomerular filtration rate (GFR) < 60 ml/min/1.73 m2 (CKD-EPI equation); urine albumin creatinine ratio ≥30 mg/g. Hepatic Transaminase (AST and ALT) levels >3x the upper limit of normal; Significant psychiatric illness (assessed using validated MINI International Neuropsychiatry Interview questionnaires); Anemia (men, Hct < 38%; women, Hct <36%); Participants working night shifts or swing shifts. Have any past or present illness of sleeping disorders including sleep apnea. Women who are pregnant or breastfeeding or who can become pregnant and not practicing an acceptable method of birth control during the study (including abstinence).