Inclusion Criteria:  Subject has signed informed consent Subject is age 40-80 Subject is able to have an MRI  Minimum of prior 12 weeks of failed response to conservative therapy for knee osteoarthritis, which may include one or more of:  a) Oral or topical NSAIDS, opioid medications, intra-articular injection of glucocorticoids or hyaluronic acid, physical therapy.  Localized tenderness in anterior knee area Kellgren-Lawrence grade 1, 2, or 3 as assessed by weight-bearing knee radiographs Synovitis present as assessed by WORMS VAS >50 mm WOMAC score >30  Exclusion Criteria:  Rheumatoid arthritis Local infection of the target knee(s) Kellgren-Lawrence grade >3 Osteonecrosis evident by MRI Prior knee arthroplasty Allergy to iodinated contrast agents that cannot be managed by prophylaxis Hypersensitivity to gelatin products Any known condition that limits catheter-based intervention or is a contraindication to embolization Active malignancy other than non-melanomatous skin cancer Subject is pregnant, breastfeeding, or pre-menopausal and intending to become pregnant Any other condition related to the subject's health and wellbeing deemed exclusionary in the opinion of the investigator