Inclusion Criteria:  women aged 18-50 having had a male child informed and not having objected to participating in the research.  Patients:  - having a diagnosis of breast cancer  Controls:  operated on for benign breast tumors cancer free  Exclusion Criteria:  autoimmune disease immunomodulatory treatment history of cancer other than breast cancer ongoing hormonal treatment women not affiliated to the social security under AME (state medical aid) under tutorship / curatorship