Inclusion Criteria:  Age 40-74 years Female Never Smoker defined as a lifetime exposure of less than 100 cigarettes Identify as from Asian descent, defined as having reported ancestry or race from the continent of Asia. Individuals with mixed heritage are eligible.  Exclusion Criteria:  Prior history of lung cancer. Treatment for, or advisement by a physician of evidence of any cancer within the past five years, with the exceptions of non-melanoma skin cancer and most in-situ carcinomas based on PI discretion. (Treatment for, or evidence of, melanoma or in-situ bladder/transition cell carcinomas within the preceding five years renders the potential participant ineligible.) Participation in a cancer prevention trial. Present symptoms suggestive of current lung cancer, including: unexplained weight loss of over 15 pounds within the 12 months or unexplained hemoptysis. Medical or psychiatric condition precluding informed medical consent. Pneumonia or acute respiratory infection within 12 weeks of enrollment that was treated with antibiotics under physician supervision.