Inclusion Criteria:  Chronic HBV/HDV Coinfection suspected or diagnosed liver cirrhosis, indication for hepatovenous pressure gradient (HVPG) measurement or liver cirrhosis and HVPG measurement conducted in the past 12 months (conducted prior to antiviral treatment) indication for antiviral treatment with Bulevirtide age >18years Must be willing to participate in the study and provide written informed consent  Exclusion Criteria:  patient rejects study participation no conducted or no indication for HVPG measurement age <18years