Inclusion Criteria:  Pregnant women 18-45 years of age at the time of consent, inclusive Intention of receiving or within 3 days of receiving the first dose or only dose of COVID-19 vaccine based on Advisory Committee on Immunization Practices (ACIP) and American College of Obstetricians and Gynecologists (ACOG) guidelines in response to the FDA Emergency Use Authorization (EUA) and in conjunction with federal and local vaccination campaign distribution plans Willing to provide informed consent in a written or electronic format Gestational age at time of consent < 34 weeks 0 days based on reconciliation of last menstrual period and ultrasound dating. Estimated due date (EDD) and Gestational Age (GA-EDD) will be based on reconciliation of "sure" first day of the last menstrual period (LMP) and earliest dating ultrasound. If the LMP is uncertain, then the earliest dating ultrasound will be used to determine EDD and GA. If the ultrasound derived-EDD is in agreement with sure-LMP derived EDD, then the LMP-derived EDD is used to determine GA. If the ultrasound derived EDD is not in agreement with the LMP-derived EDD, the ultrasound-derived EDD is used to determine GA. Intention of being available for entire study period and complete all relevant study procedures, including follow-up phone calls and collection of delivery information. English or Spanish literate  Exclusion Criteria:  Has immunosuppression as a result of an underlying illness. Stable hepatitis B, hepatitis C, or HIV are permitted per the following parameters  If known hepatitis C (HCV): evidence of sustained virological response for > or + 12 weeks after treatment or without evidence of HCV RNA viremia (undetectable HCV RNA) If known hepatitis B (HBV): confirmed inactive chronic HBV infection: HBsAg present for > or = 6 months and HBeAg negative, anti-HBe positive; serum HBV DNA <2000 IU/mL; persistently normal alanine transaminase (ALT) and/or aspartate transaminase (AST) levels; in those who had liver biopsy, findings that confirm absence of significant necroinflammation If known HIV infection: confirmed stable HIV disease defined as document viral load (VL) <50 copies/mL and CD4 count >200 within 6 months before enrollment, and on stable antiretroviral therapy for at least 6 months) Use of oral, parenteral, or high-dose inhaled glucocorticoids Has an active neoplastic disease (excluding non-melanoma skin cancer), including those who used anti-cancer chemotherapy or radiation therapy during the current pregnancy Signs or symptoms of active preterm labor, defined as regular uterine contractions with cervical change (dilation/effacement) Known fetal congenital anomaly, e.g. genetic abnormality or major congenital malformation based on antenatal ultrasound Anyone who is already enrolled or plans to enroll in another randomized clinical trial with any drug, vaccine or medical device. Co-enrollment in behavioral or other observational intervention studies are allowed at any time. Any condition which, in the opinion of the investigators, may pose a health risk to the subject or interfere with the evaluation of the study objectives. Anyone who is a relative of any research study personnel or is an employee supervised by study staff.