Inclusion Criteria:  Age of patients ≥ 18 years old patients. Histopathology confirmed: invasive ductal carcinoma. Breast conservative surgery or mastectomy. Early stage breast cancer patients. Adjuvant chemotherapy in the form of Anthracyclins based.  Exclusion Criteria:  Contraindications to radiotherapy: such as previous irradiation to chest wall or skin diseases. Pregnancy or lactation. Contraindications to capecitabine such as: severe renal impairment Or hypersensitivity to capecitabine.