Inclusion Criteria:  ≥ 18 and <70 years Performance status, ECOG 0-1 Histologically proved adenocarcinoma in colon or rectum BRAF wild-type CRC on primary tumor or liver metastases High standard oncological surgical resection of the primary tumor Liver metastases not eligible for curative liver resection confirmed by the validation committee At least one line (3 months) of chemotherapy At least 6 months time span from CRC resection and date of being listed on the transplantation list. At least 8 weeks of tumor control: stable disease or partial response according to RECIST 1.1 criteria No signs of extra hepatic metastatic disease or local recurrence on CT, MRI and Pet-CT except patients may have <3 lung lesions all<15mm resected or treated by radiotherapy or metastatic hilar nodes treated by resection and without recurrence at 3 months from resection or radiotherapy. Satisfactory blood tests creatinine in normal level, PLT >60.000/mm3, GB>2500/mm3 CEA stable or in decrease Signed informed consent and expected cooperation of the patients for the treatment and follow up  Exclusion Criteria:  Weight loss >10% the last 6 months Patient BMI > 30 Participation refusal General contraindication to LT Other malignancies in the previous 5 years Pregnancy or breast feeding Any reason why, in the opinion of the investigator, the patient should not participate