Inclusion Criteria:  Patients who have been diagnosed with hepatocellular carcinoma. Planned to receive hepatectomy. Liver function Child-Pugh A/B. GPC-3 was validated highly expressed preoperatively. Aged 18 to 75, and the expected lifetime is longer than 6 months. Approved to sign the informed consent.  Exclusion Criteria:  Allergic to IRDye800. Enrolled in other trials in the past 3 months. Another malignant tumor was found. Undesirable function of heart, lung, kidney, or any other organs. Unable to tolerate a hepatectomy. The researchers considered inappropriate to be included.