Inclusion Criteria:  Sign informed consent, able to follow protocol requirements Aged 18 to 75 years, male or female Dose escalation stage: Histopathology or cytology proven advanced solid tumor with positive C-myc who have developed progressive disease or intolerability after at least one line of standard systemic therapies Dose expansion stage: Histopathology or cytology proven advanced pancreatic cancer with positive C-myc who are not suitable for surgery or local treatment, have developed progressive disease or intolerability after at least one line of standard systemic therapies Positive C-myc refer to C-myc overexpression: more than 10% tumor cells are detected 1+ by immunohistochemistry (IHC) ECOG Performance Status score: 0 to 2 points Expected survival is > 3 months  Adequate hematologic and organ functions (without persistent supportive treatment)  Absolute Neutrophil Count > 1.5 × 109/L, Platelet count ≥ 75 × 109/L, Hemoglobin > 8.5 g/dL INR and PT ≤ 2 × ULN Alb > 3.0 g/dL, Bilirubin level ≤ 2 × ULN, AST and ALT ≤ 2 × ULN or < 5 × ULN in the presence of liver metastases Calculated creatinine clearance (e.g. Cockcroft-Gault) ≥ 60 ml/min or serum creatinine ≤ 1.5 × ULN  f. Left ventricular ejection fraction (LVEF) ≥ 50%. Heart rate (HR) ≥ 60 bpm. QT intervals, male ≤ 450 ms, female ≤ 470 ms  According to RECIST 1.1, patients have at least one evaluable target lesion(only for dose expansion stage) Female patients of child-bearing potential or male subjects whose spouses are women of childbearing potential must agree to use a reliable method of contraception (IUD, oral contraceptive, condom) throughout the treatment period and for 3 months after discontinuation of WBC100. Female patients of child-bearing age must undergo a serum pregnancy test before the initiation of the study and the result must be negative.  Exclusion Criteria:  Allergic to WBC100 or its excipients or with allergic constitution Major surgery, active ulcer or unhealing wound occurred within 4 weeks before first dose Taken drugs in other clinical trials within 4 weeks or still in the safety follow-up period Subjects have Spinal compression, brain metastases and meningeal metastases (subjects who is asymptomatic, stable or with no need for steroid for at least 4 weeks before first dose are allowed) Subjects have history of cardiac insufficiency (NYHA III-IV) or uncontrolled congestive heart failure (NYHA II-IV) within 6 months before consent Subjects have risk factors of QT intervals prolongation or arrhythmia, such as Idiopathic Q-T interval prolongation syndrome or history of drug induced arrhythmia Subject have any condition within 6 months before consent: unstable angina pectoris requiring surgical intervention, uncontrolled hypertension (systolic pressure ≥ 140 mmHg, diastolic pressure ≥ 90 mmHg), myocardial infarction, stroke (lacunar infarction is allowed), Coronary/peripheral artery bypass surgery, pulmonary embolism Infection of HIV, active infection of HBV (HBV-DNA ≥ upper limits of normal) active infection of HC (HCV-RNA ≥ upper limits of normal) History of severe infection within 28 days before enrolled, including uncontrolled infection requiring systemic treatment of bacteria, virus and fungus The side effects caused by the previous treatment of the subjects did not return to grade ≤1 according to CTCAE 5.0 with exception of tolerable events determined by investigator such as hair loss and grade 2 Peripheral neuropathy Subjects with uncontrolled nausea or vomiting, chronic gastrointestinal diseases, unable to swallow pills, enterostomy, uncontrolled diarrhea or any intestinal surgery that cause insufficient absorption of WBC100 Subjects taking any CYP inducers or inhibitors or Chinese medicine within 7 days prior to the first dose of study drug History of malignancy in the last 2 years with the exception of patients with prior history of in situ breast cancer, in situ cervical cancer, basal or squamous cell skin cancer who have already been cured Subjects who have antitumor therapy within 28 days prior to first dose of WBC100, such as monoclonal antibody, chemotherapy, radiotherapy and Chinese medicine Subjects have mental disorders or history of drug abuse that may limit subjects' participation in this trial Unable to tolerate intravenous blood collection According to the investigators' evaluation, patients are unable or unwilling to comply with the requirements of the study protocol