Inclusion Criteria: Dilated cardiomyopathy diagnosed by medical history, physical examination and echocardiography.  -  Exclusion Criteria:  Cardiac enlargement caused by other factors such as myocardial ischemia, myocarditis, diabetic cardiomyopathy, valvular heart disease, congenital heart disease, Patients who had underwent heart transplatation. Individuals not suitable for the present study due to maligant tumor or severe trauma.