Inclusion Criteria:  Healthy subjects aged 2months (60-89 days) and 3months (90-119 days) ； Willing to provide proof of identity Subjects aged 2 months have not been vaccinated with DTaP, IPV, Hib, or 13-valent pneumococcal polysaccharide conjugate vaccine; Subjects of 3 months have not been inoculated with DTaP vaccine, and IPV (only group A3）； Subjects'guardians or trustees are able to understand and sign the informed consent voluntarily, comply with the requirements of the clinical study plan.  Exclusion Criteria:  With temperature >37.0°C on axillary setting before vacciation; With a medical history of diphtheria, pertussis or tetanus; Had contact with individuals with confirmed pertussis, diphtheria and tetanus diseases in their families in the past 30 days; Premature birth (delivery before the 37th week of pregnancy)or low birth weight (birth weight< <2500g); History of dystocia, suffocation rescue, neurological damage; With congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. History of epilepsy, convulsions or convulsions, or have a family history of mental illness; History of abnormal blood coagulation (such as coagulation factor deficiency, coagulopathy); Had received immune enhancement or inhibitor therapy (continuous oral or instillation for more than 14 days); History of severe allergic reactions to vaccination, such as difficulty breathing, urticaria; Any prior administration of blood products in last 3 month; Any prior administration of attenuated live vaccine in last 14 days; Any prior administration of subunit or inactivated vaccines in last 7 days; Plans to participate in or is participating in any other drug clinical study; Has any other factors judged by investigators that make them unfit to participate in the clinical trial