Inclusion Criteria:  Body mass index (BMI) 18.5 - 30 kg/m2 Age 18 - 40 Non-smoker  Exclusion Criteria:  Body mass index (BMI) < 18.5 or > 30 kg/m2 Age < 18 or > 40 Smoking Cardiovascular disease Hypertension (≥ 140/90 mmHg) Metabolic disease Medications known to affect vitamin C metabolism A known vitamin C deficiency Less than 2 hours per week of physical activity or following a structured exercise training program. Routine use of vitamin C supplements