Inclusion Criteria:  Adult participants 18 to 65 years of age (inclusive) at the time of informed consent. A primary diagnosis of binge eating disorder (BED), or is diagnosed at screening, according to Diagnostic and Statistical Manual of Mental Disorders - 5th Edition (DSM-5) criteria and confirmed by the Structured Clinical Interview for DSM-5 (SCID). BED with a history of at least moderate severity. A rating of 4 or higher on the Clinical Global Impression - Severity (CGI-S) at screening and baseline. Body mass index (BMI) of 18 to 45 kg/m^2, inclusive.  Exclusion Criteria:  Lifetime history of bulimia nervosa or anorexia nervosa. Participation in a formal weight loss program within 3 months of screening or planning to start a weight loss program during the trial. History of bariatric surgery. Montgomery-Asberg Depression Rating Scale (MADRS) score ≥ 18.