Inclusion Criteria:  Participants must: 1) be enrolled in their high school's School-Based Health Center; 2) report NOT having engaged in any prior opioid misuse; 3) be at "high-risk" based on their report at baseline of past 30-day use of cigarettes, e-cigarettes, Juul, alcohol, marijuana (including synthetics), amphetamine, cocaine, benzodiazepines, ecstasy, bath salts, or any other misuse of non-opioid prescription drugs or use of non-opioid illicit drugs OR have a score of ≥1 on the PHQ-2 OR a score of ≥1 on the GAD-2 (both screening tools used by SBHA); 4) be willing to sit for 60 minutes/session to play the game; 5) be able to provide assent/parental/guardian consent (if under age 18).  Exclusion Criteria:  Failure to meet any of the inclusion criteria.