Inclusion Criteria:  Patients with oral acute poisoning who were first diagnosed in our hospital and completed gastric lavage; The skin of umbilical cord and bilateral Zusanli acupoints had no injury, scar, rash and other skin diseases. The patient or the patient's family member signed the informed consent and expressed their willingness to receive treatment.  Exclusion Criteria:  Patients with severe conditions requiring cardiopulmonary resuscitation or with severe trauma or multiple injuries; Patients with heart, brain, liver, kidney and hematopoietic system diseases and other serious primary diseases; Patients with a history of gastrointestinal diseases (such as postoperative cancer, intestinal obstruction, and large intestinal polyps) that affect gastrointestinal emptying; Failing to receive treatment according to regulations or taking poison again during hospitalization and unable to judge the curative effect.