Inclusion Criteria:  not living with HIV weight >35 kg receiving OB/GYN care in our preselected clinics GYN patients: positive sexually transmitted infection (STI) diagnosis within past 6 months, or if seeking STI testing and a have a history of an STI OB patients: at least one positive answer to the following risk screen: inject illicit drugs; sex with a partner who injects illicit drugs; any past STIs; sex with a partner who has sex with both men and women; sex for money, drugs, other payment; sex with a partner currently infected with HIV; sex with more than one partner  Exclusion Criteria:  symptoms or clinical signs consistent with acute HIV infection unknown HIV infection status allergies to the active substances or any excipients of PrEP estimated creatinine clearance of <60 mL/minute active Hepatitis B infection participating in other clinical studies related to HIV and/or antiretroviral therapy