Inclusion Criteria:  Diagnosed with laboratory supported probable, clinically possible, probable or definite ALS according to the World Federation of Neurology Revised El Escorial criteria (83) (Appendix A) Disease duration from symptom onset no greater than 36 months at the Screening Visit Aged 18 years or older Capable of providing informed consent and complying with study procedures If taking riluzole, on a stable dose for at least 30 days prior to Screening Visit If taking edaravone, on a stable dose for at least one cycle prior to Screening Visit If on BiPAP, average usage of no more than 12 hours per day at time of Screening Visit Able to swallow a capsule at Baseline Visit Fluency in English or French  Exclusion Criteria:  Exposure to any investigational agent or Withania somnifera (Ashwagandha) within 30 days prior to the Screening Visit; simultaneous participation in other observational studies is allowed upon Site Investigator approval  Presence of any of the following clinical conditions:  Substance abuse within the past year Unstable cardiac, pulmonary, renal, hepatic, endocrine, hematologic, or active malignancy or infectious disease Acquired Immunodeficiency Syndrome (AIDS) or AIDS-related complex Unstable psychiatric illness defined as psychosis (hallucinations or delusions) or untreated major depression within 90 days prior to the Screening Visit Hypersensitivity or allergy to Withania somnifera Uncontrolled diabetes with severe associated complications (such as neuropathy) Untreated hypertension, active stomach ulcers, or untreated thyroid disorder Previously diagnosed auto-immune condition with or without neurological manifestations (e.g. multiple sclerosis (MS), systemic lupus erythematosus (SLE), rheumatoid arthritis, etc.) Current or planned use of oral, intramuscular or intravenous steroid drugs (such as prednisone, prednisolone, dexamethasone, triamcinolone, methylprednisolone, oxandrolone, and others) or immunosuppressant drugs (azathioprine, mycophenolate, tacrolimus, sirolimus, cyclophosphamide, and others) for more than 7 days Planned consumption of alcohol, other drugs or natural health products with sedative and anxiolytics properties while taking study drugs (8 week duration) Current or planned use of continuous subcutaneous, intravenous or oral anticoagulant drugs Scheduled for surgery under general anesthetic within 14 days of Screening Visit Pregnancy or planned pregnancy. Women of childbearing potential must have a negative pregnancy test and be non-lactating at the Screening Visit Insertion of a diaphragm pacing system