Inclusion Criteria for QST:  Age ≥18 years Meet either the 1987 or 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria for RA Persistent joint symptoms ≤ 1 year Active inflammatory disease If taking opioids on an as needed (prn) basis, must be able to hold opioid for 48 hours before study procedures If taking NSAIDs, must be able to hold NSAIDS for 24 hours before study procedures If taking a central-acting pain medication, must be on a stable dose and able to stay on a stable dose throughout study  Exclusion Criteria for QST:  Routine, scheduled opioid use Routine, scheduled prednisone dose >10 mg or its equivalent Peripheral neuropathy Peripheral vascular disease Raynaud's phenomenon requiring treatment, manifested by claudication or ischemic rest pain Uncontrolled blood pressure  Additional Inclusion Criteria for neuroimaging:  Age <75 years old Right-handed Ability to lie on their back for the duration of the MRI scans  Additional Exclusion Criteria for neuroimaging:  Severe claustrophobia precluding MRI Body mass index >40 kg/m2 Pregnant Contraindications to MRI