Inclusion Criteria:  Patients with a macula hole that falls into the two categories below: Patients with idiopathic macular hole (with no history of secondary macular hole) ≥ 600 microns (measured using optical coherence tomography) Patients with an idiopathic macular hole submitted to conventional treatment without closing it (of any size). History of the disease less than 18 months Aged over 18 years old Visual acuity less than 20/32  Exclusion Criteria:  History of any previous macular disease other than idiopathic macular hole Macular hole of other causes (secondary) Patients with diabetic retinopathy or other retinal vascular diseases Eyes subjected to intravitreal injection of any medication Visual acuity <20/400 of any retinal cause in the contralateral eye or absence of the globe *Aged under 50 years old Cataract and anti-glaucoma surgery less than 3 months before the study Glaucoma with optic nerve excavation > 0.7 in the studied eye Intraocular pressure > 24 mmHg with the use of maximum medication in the studied eye History of vitreoretinal surgery for a condition other than the idiopathic macular hole (retinal detachment, vitreous hemorrhage) History of retinal detachment of any etiology A patient who manifests himself not being able to perform the head position in the postoperative period A patient with active anterior or posterior uveitis