Inclusion Criteria:  Female partners' >18< 40 years Male partners' >18< 40 years Patients undergoing assisted reproductive technology with donor sperm or husband's semen due to male factor  Exclusion Criteria:  Female partners with polycystic ovary Female partners with insufficiency or premature ovarian failure Female partners with endometriosis Female partners with abnormal profile of thyroid hormones Chromosomal abnormalities of either spouse Mental disorder of either spouse