Inclusion Criteria:  Couples with primary / secondary infertility who are planned to undergo ICSI treatment with PGT-A Age of each partner above 18 years  Exclusion Criteria:  Couples with consanguinity (couple who is 1st or 2nd degree cousins) Couples in whom the female partner has a history of: Chemotherapy or radiation which impacts the ovarian reserve Surgery at the ovaries / adnex region Endometriosis Couples in whom the male partner has a history of: Chemotherapy / Radiation which impacts the semen result Surgery at the testicles Vasectomy Surgery for reversal of vasectomy Semen obtained by fine needle aspiration (FNA) or Testicular sperm extraction (TESE)