Inclusion Criteria:  Patient, male or female, > 18 years of age at the time of inclusion in the study Patient who had a non-surgical root canal treatment with Endomethasone N, in a context of an endodontic treatment, or retreatment, before 01-Mar-2016 Having a documented patient follow-up visit (clinical examination and radiographic examination) at least 5 years after the endodontic treatment or retreatment with Endomethasone N Patient affiliated or beneficiary of a social security system Patient informed about the study and who confirm their non-opposition in participating in the study  Exclusion Criteria:  History of malignant tumors in the 5 years prior to the root canal treatment Non-stabilized systemic disease during the month prior to the root canal treatment (diabetes, hypertension, thyroid disorders, etc.) Patient who developed a systemic pathology after the root canal treatment with Endomethasone N Patient who had endodontic treatment with Endomethasone N obturation on a wisdom tooth Patient whose tooth has suspected perforation during endodontic treatment Patient suffering from active non-stabilized periodontitis, untreated during endodontic treatment Patients participating in an interventional clinical trial at the time of root canal treatment