Inclusion Criteria:  Age ≥ 18 years Willing to provide informed consent prior to participation. Cohort 1 (Arm 1) - Positive test results for SARS-CoV-2 virus by an RT-PCR or Antigen test AND not received any COVID-19 vaccine or participated in any COVID-19 vaccine trial Cohort 2 (Arm 2) - Received the COVID-19 vaccine  Exclusion Criteria:  Unable or unwilling to provide informed consent Individuals with known conditions or treatments associated with immune impairment, such as cancer and chemotherapy