Age ≥ 18 years. Both genders. Heart Failure (2021 European Society of Cardiology criteria) Any LVEF value. Outpatients or hospitalized patients in Internal Medicine Units  Patients with suspicion criteria proposed by the European Society of Cardiology:  Ventricular hypertrophy ≥ 12 mm  And one or more of the following criteria:  Heart failure in ≥ 65 years Aortic stenosis in ≥ 65 years Hypotension or Normotensive if previously hypertensive Sensory involvement, autonomic dysfunction Peripheral polyneuropathy Proteinuria Skin bruising (eg, periorbital purpura) Bilateral carpal tunnel syndrome Ruptured biceps tendon In CMR: Subendocardial / transmural late gadolinium enhancement (LGE), or increased extracellular volume (ECV) In ECO: Reduced longitudinal strain with apical sparing Reduced QRS voltage to mass ratio Pseudo Q waves on ECG Atrioventricular conduction disease Possible family history of ATTRv  Exclusion Criteria:  Refusal to participate in the registry