Inclusion Criteria:  Adults (age 18-no limit years) who will be diagnosed covid-19 With destructive inflammatory immune response needing ICU admission to be run on steroid therapy.  Exclusion Criteria:  Severe immunosuppression like HIV (Human immunodeficiency Virus) Long term use of immunosuppressant for any other chronic illness Pregnant or lactating females Patients who are on chronic use of corticosteroids like asthma, rheumatoid arthritis.