Inclusion Criteria:  DCIS spanning 2 cm or less based on its radiographic appearance by mammography and/or breast contrast-enhanced MRI Diagnosis of DCIS by minimally invasive needle biopsy No prior history of DCIS or invasive breast cancer in the same breast No history of surgical biopsy and/or lumpectomy for diagnosis/treatment in the same breast Adequate breast volume and skin clearance to permit cryoablation as assessed by Dr. Holmes. This excludes male and females with breasts too small to allow safe cryoablation Non-pregnant, non-lactating, and no history of pregnancy within the preceding 6 months No history of breast radiation in the same breast