Inclusion Criteria:  More than or equal to 18 years of age Clinician diagnosed LN participants. At least one visit to the investigational center during 12 months prior to the baseline visit, recorded in medical documentation. Literacy in English or Arabic allowing to fully comprehend the written informed consent and study-specific patient reported questionnaires.  Exclusion Criteria:  Incomplete medical records to be able to assess the disease severity or absence of any of the following renal laboratory results from the medical record within the last twelve months: a. Urinary protein to creatinine ratio (UPCR) or 24-hour proteinuria or urine sediment (activity). b. Serum creatinine or estimated glomerular filtration rate (eGFR); or measured glomerular filtration rate (GFR), if eGFR is not available. Current or medical history of: a. Congenital or acquired immunodeficiency. b. Malignancy in active treatment phase. c. Acute viral infection, such as human immunodeficiency virus (HIV) infection, requiring hospitalization.