Inclusion Criteria:  Have a body mass index (BMI) between 25 to 40 kilograms per meter squared (kg/m²), For participants with a confirmed type 2 diabetes diagnosis: The condition must be managed either by diet and exercise alone or on a stable dose of metformin For nondiabetic subjects: participants must agree to keep their diet and physical activity habits stable throughout the study Female participants must be post-menopausal and male participants  Exclusion Criteria:  Poorly controlled diabetes Unstable body weight within 30 days prior to screening. For non-diabetic control subjects: evidence of diabetes or prediabetes at screening. Having worked as a metal worker or welder History of alcohol or drug abuse within 5 years of the screening Currently participating, or previous participation in another clinical trial within 30 days prior to the screening visit, or previous participation in another PET imaging study within 12 months.