Inclusion Criteria:  Minor patient over 1 month old (and over 36 WA of corrected age) and under 18 years old Hospitalized in neonatal or pediatric intensive care unit Invasive mechanical ventilation over 72 hours Prolonged sedation greater than 72 hours  Exclusion Criteria:  - Opposition of the holders of parental authority of the minor patient or the adult patient to the use of the data for the study