Inclusion Criteria:  Voluntarily participate in this clinical trial, and are willing to sign informed consent forms. Male or female aged from 18-75 years old (inclusive). Diagnosed with histologically or cytologically confirmed advanced solid tumors. Evaluable lesions defined by RECIST v1.1. Eastern Cooperative Oncology Group performance status of 0 to 1. Subjects or their legal representatives are able to communicate well with Investigators and are willing to comply with the protocol and complete the study.  Exclusion Criteria:  With clinically significant cardiac diseases With clinically significant digestive disorders. Other severe disease. Pregnant or lactating women. Other unfavorable situations for subjects to participate in the study judged by Investigators.