Inclusion Criteria:  Recurrent anal cancer Bioptically verified (squamous cell carcinoma) Available dose plan from primary radiotherapy Previous RT (>30Gy EQD2) Evaluated in MDT-conferences (Herlev, Aarhus) Age>18 years PS 0-2 Adequate organ function Written informed consent  Exclusion Criteria:  Distant metastases deemed without curative intended treatment options (PET-CT) Unable to undergo MRI, PET-CT Inability to attend full course radiotherapy and follow up in the outpatient clinic.