Inclusion Criteria:  patient specific:  Age > 18 years. Subjects with stable angina pectoris, unstable angina pectoris or NSTEM1 and in whom invasive FFR was performed to assess a non-culprit stenosis in at least one coronary artery.  Angiographic:  Subject underwent a clinically indicated Invasive Coronary Angiogram (ICA). Subject underwent invasive FFR with IV or intracoronary Adenosine, Adenosine Triphosphate (ATP) or Papaverine used as hyperemic stimulus.  Exclusion Criteria:  Patient Specific:  Angiogram not obtained on an FDA cleared C-Arm angiography system. Invasive FFR not obtained on an FDA cleared FFR catheter tip pressure transducer (a.k.a. pressure wire). Vessel size less than 2 mm. Subject presents with an acute infarct (STEM1) OR has documented prior STEMI on same side (right/left). CTO in target vessel. Prior CABG, heart transplant or valve surgery, prior TAVI/TAVR or severe left sided valvular disease. Known LVEF ≤45%. Arteries supplying akinetic or severe hypokinetic territories if already known based on prior imaging. TIMI Grade 2 or lower at baseline. Target lesion involves Left Main (stenosis >50%). PCI with stent in target vessel in past 12 months, or target vessel involves in-stent restenosis. Severe, diffuse disease defined as the presence of diffuse, serial gross luminal irregularities present in the majority of the coronary tree. Target coronary vessel provides collaterals to a chronically occluded vessel.  Angiographic:  Coronary angiography was performed per standard of care at a cine frame rate of at least 7 frames per second. Presence of aortic damping. Distortion of the waveform. A minimum of two different angiographic views for each lesion of interest in the Left Circumflex Artery (LCX), Left Descending Artery (LAD) and in the Right Circumflex Artery (RCA). Lesion is not clearly visible.