Inclusion Criteria:  Between the ages of 18-50, With an Extended Disability Status Scale (EDSS) score of 4 or less, No regular exercise habit Able to walk on the treadmill, No pregnancy, Not receiving corticosteroid treatment in the last month, Fampridine etc. in the last 1 month. not taking medication, Patients who have not received Botox treatment in the last 6 months  Exclusion Criteria:  patients who do not agree to volunteer