Inclusion Criteria:  One eye had an acute attack, which could not be relieved by medication, and the intraocular pressure was more than 21mmhg; The patients were 40 to 80 years old, regardless of gender; Patients are able and willing to comply with the research guidance and may complete all visits required by the research; Informed consent has been signed.  Exclusion Criteria:  History of ocular trauma; Any previous intraocular surgery; Secondary glaucoma was diagnosed, including uveitis, neovascular glaucoma, glaucoma with elevated superior scleral venous pressure, lens dissolution glaucoma, glaucoma caused by lens dislocation, lens cortical glaucoma, pigmented glaucoma, etc; The patient's history indicated that he had severe dysfunction of heart, lung, liver and kidney; Women in pregnancy, lactation or planned pregnancy; The researchers believe that the patient's condition may put the patient at a significant risk, may confuse the results of the study, or may significantly interfere with the patient's participation in the study.