Inclusion Criteria:  locally advanced non-metastatic HNSCC patients older than 70 years Primary tumor clinically and radiologically detectable and measurable (staging according to ed. TNM VII and also VIII. patients defined by the tumor board (ENT, Oncologist, Radiotherapist, Nutritionist) as 1) not eligibles for RTCT / RT-cetuximab treatment 2) not amenable to radical surgery and 3) not candidates for treatments with palliative intent/best supportive care Availability of staging with CT/PET for distant metastasis and CT/MRI for primary tumor Karnofsky performance status (KPS) ≥60/100 Oropharynx , Hypopharynx and Larynx, Oral cavity: stage III and IV and Unknown primitive P16-POSITIVE  Exclusion Criteria:  Age less than 70 years  Staging exams done 45 days before the date of the beginning of the treatment Subsites: nasopharynx, salivary glands, paranasal sinuses. Metastatic disease Gross total excision All subsites concerned if N3. Squamous cell neoplasms of the glottic larynx T1-T2 N0. Unknown primary HPV negative or EBV positive. Presence of distant metastases or sub-clavicular lymphadenopathies. Previous surgery on T and/or N except diagnostic tonsillectomy. 3D-conformational radiotherapy technique