Inclusion Criteria:  I. Criteria for the inclusion of the CA monitoring method in cardiac surgery:  Age 18-90 years. The patient, after reading the personal information form, confirms in writing his / her consent to participate in the study. An AVJS operation is planned. No ophthalmological or neurological disorders have been identified prior to surgery.  II. Criteria for the inclusion of the CA monitoring method in ophthalmology:  Age 18-90 years. The patient, after reading the personal information form, confirms in writing his / her consent to participate in the study. Patients with glaucoma changes in the optic disc and eye area shall be included in the study group. The control group shall include volunteers who are free from glaucoma, acute or chronic uncompensated disease that may affect the results of the studies, and age and anthropometric data from other study groups.  Exclusion Criteria:  No written consent of a person to participate in a biomedical research has been obtained; Persons under 18 years of age. A woman who may become pregnant, be pregnant or breastfeeding. The patient is allergic or sensitive to local anesthetics. Patients with an eye disease that may distort the results of the test, if so decided by the researcher. The patient had an orbital or eye injury. Has an acute or chronic but currently exacerbated respiratory disease. Patients with uncompensated cardiovascular diseases (II-III AV block or cardiogenic shock). Diabetes mellitus treated with more than one hypoglycaemic agent and / or insulin injections. Cognitive impairment diagnosed before surgery History of neurological diseases It is not possible to perform a qualitative neuropsychological examination due to other reasons (hearing, vision, etc. disorders)