Inclusion Criteria:  M/F, 18-65 years of age Ulcerative Colitis with Inactive Disease (Mayo Score ≤ 2; partial Mayo Score ≤ 1 with endoscopic score 0-1) Subclinical inflammation (stool calprotectin >50 or CRP > 8 mg/L) Stable medications with no disease flares for the > 3 months Normal psychological evaluation and negative drug screen (See Below)  Exclusion Criteria:  Active UC at enrollment (Mayo > 2 and/or sigmoidoscopy score of 2 or 3) Prior ostomy or subtotal colectomy Recent prednisone or antibiotic use in last 12 weeks Use of biologic or immunomodulatory medications (i.e. Infliximab, Adalimumab, azathioprine, Vedolizumab, methotrexate, etc.) Major Depression identified as Beck Depression Inventory (score ≥14) Restless leg syndrome (score ≥ 15 on the IRLS Study Group Rating Scale) Sleep apnea (score high risk ≥ 2 or more categories on the Berlin Questionnaire) Clinically significant diabetes (Hgb-A1c>7) Regular use of medications that affect intestinal permeability, intestinal motility and/or endogenous melatonin including metoclopramide, NSAIDs, beta blocker, psychotropic medication, hypnotics and exogenous melatonin products during 4 weeks prior to the study Atypical American diet (FFQ 5-15 g fiber per day) Clinically significant cardiac, renal (creatinine > twice normal) or liver disease Alcohol use disorder (AUDIT>8) Chronic use of illicit drugs Shift Work Children under 6 months Inability to sign an informed consent