Inclusion Criteria:  Adults Signed declaration of consent  Presence of a confirmed diagnosis of  Inflammatory bowel diseases Irritable bowel syndrome Gastrointestinal diseases, except participants with diagnosis of group 1 or 2 (e.g. celiac disease, food allergies, microscopic colitis, diverticulosis, diverticulitis) Healthy controls as part of a preventive medical check-up  Exclusion Criteria:  No indication for endoscopic examination as part of routine care Age under 18 years