Inclusion Criteria:  Patients with 2° or 3° stage lower limb/ sacrum located pressure ulcers; Patients with 2° or 3° stage pressure ulcers with a ≥ 2cm² lesion area; Patients with a hospitalization waiting time < 30 day; Men and women aged ≥ 50 years; Patients with a Braden scale score ≥ 11;  Exclusion Criteria:  Patients who are participating in other clinical trials with drug or medical device; Patients with third stage pressure lesions, on the lower limbs or on the sacrum, with undermining wounds, tunneling or eschar; Patients with systemic or superficial infection at the time of recruitment, that need systemic antibiotic therapy; Patients with a history of self-harm who can voluntarily alter the course of healing; Patients under intravenous therapy with doses of corticosteroids above 40mg/day; Patients under immunosuppressant or cytostatic drugs therapy; Women who are pregnant or breastfeeding1; Patients with neoplasia; Patients with pathologies that induce skin photosensitivity; Patients with a life expectancy of less than 30 days.