Inclusion Criteria:  Patient's age: From 21 years. Acute symptoms on a background of at least a 3-month history of chronic pain or swelling of the shoulder joint with radiological confirmed (X-ray or MRI) Mild or moderate osteoarthritis of the shoulder joint according to The Samilson-Prieto classification. Numerical Rating Scale for pain scores greater than five on a 10 scale  Exclusion Criteria:  Under 21 years of age Severe osteoarthritis according to The Samilson-Prieto classification. (Figure 1) Neuropsychiatric disorders. Immunocompromised patients. Active infection or malignancy at the joint. Pregnancy and breastfeeding. Patients may have thrombocytopenia, bleeding disorders, or on anticoagulant therapy. Shoulder surgery within 3 months or inflammatory arthritis; previous infection of the shoulder joint.