Inclusion Criteria:  Biopsy proven adenocarcinoma of the prostate Indication for ePLND combined with robot assisted radical prostatectomy (RARP) (MSKCC nomogram >5%, if not applicable when only MRI targeted biopsies are positive, the Briganti nomogram will be used) Suitable for robot-assisted ePLND and RARP Mentally competent and understanding of benefits and potential burden of the study Written informed consent No known allergies for PSMA tracer.  Exclusion Criteria:  History of prior diagnosed or treated PCa Known concomitant malignancies (except Basal Cell Carcinoma of the skin) Unwillingness or inability to undergo PSMA PET/CT and/or ePLND and RARP PSMA non-avid PCa (local tumor activity) Presence of distant metastasis (M1)