Inclusion Criteria:  Age 18-35 years BMI: 28-40 kg/m2 Sedentary lifestyle Consistent diet patterns Weight-stable (<4 kg change over the last 3 mo) Willingness to adhere to resistance training protocol and not change diet Non-smoker >1 year or more  Exclusion Criteria:  Disabilities preventing adherence to resistance training protocol Recent start of medications that affect metabolism or appetite Anti-inflammatory medications and antibiotics Diabetes, hypertension, cardiovascular disorders, or dyslipidemia, requiring drug therapy Gastrointestinal disease and/or bariatric surgery Smoking Illicit drug use Pregnant or lactating individuals