Inclusion Criteria:  Patients who are clinically diagnosed with acute ST-segment elevation myocardial infarction and are planned to undergo PCI; Volunteer to participate and sign the informed consent  Exclusion Criteria:  Coronary angiography suggests that it is not suitable for PCI; Have performed CABG surgery in the past; Lesion of left or right coronary ostium; The target vessel is an infarct-related artery (old or acute myocardial infarction recovery period); The immediate effect of target vessel PCI is not ideal (such as: final TIMI blood flow <grade 3, dissection with restricted blood flow, side branch occlusion with diameter> 1.5 mm, distal embolism or thrombus shown by angiography); Severe systemic infection; Patients with malignant wasting disease whose estimated survival time is less than 1 year.