Inclusion Criteria:  Adult patient (≥ 18 years) hospitalized in targeted short-stay (MCO) and long-stay (LTC) services for each of the three identified regions French-speaking patient Patient affiliated to the social security system or, failing that, to another health insurance system Patient able to give free, informed and written consent  Exclusion Criteria:  History of blood transfusion, vascular filling, dialysis or polyvalent immunoglobulin infusion. Patient deprived of liberty Patient under court protection Patient in an emergency situation Patients unable to give personal consent, including adults under guardianship