Inclusion Criteria:  All participants must be between the ages 18-55 Meet SCID for DSM-5 diagnostic criteria for cannabis use disorder, moderate to severe Meet SCID for DSM-5 diagnostic criteria for Major Depressive Disorder Be an outpatient receiving a stable dose of antidepressant medication for at least three months (to ensure stability of depressive symptoms Have a Hamilton Depression Rating Scale (HDRS-17) at baseline assessment in the range of 12-25.. Have a Full-Scale IQ ≥ 80 as determined by the WTAR Be a non-treatment seeking cannabis user Evidence of sufficient motivation and effort as measured by a Test of Memory Malingering (TOMM) score ≥ 45.  Exclusion Criteria:  Meets criteria for substance use disorder of alcohol or other illicit substances within the past 6 months (with the exception of cannabis, nicotine, or caffeine) Positive urine screen for illicit substances other than cannabis, nicotine, or caffeine Current suicidal or homicidal ideation Psychotic disorder diagnosis (e.g. schizoaffective disorder, major depression with psychotic features) as determined by the SCID Treatment seeking for cannabis use Meet SCID for DSM-5 diagnostic criteria for Bipolar Disorder Head Injury> 5 minutes LOC Exceed upper and lower cut-offs on HSRD-17 (See Inclusion Criteria)