Inclusion Criteria:  Patients with acute pesticide intoxications with poison severity score 2 or 3 admitted in ICU of PCC-ASUH  Exclusion Criteria:  Patients less than 18 years and more than 65 years. Pregnant and lactating females. Presence of medical diseases (e.g. renal, hepatic, cardiovascular, neurological diseases and chronic pancreatitis.) Allergy to soya-, egg-or peanut protein