Inclusion Criteria:  aged between eighteen and sixty-five ASA I-III undergo elective breast cancer surgery  Exclusion Criteria:  under 18 years of age or over 65 years of age ASA IV and above declined to give written informed consent contraindications of peripheral blocks or local anesthetic infiltration history of allergy against local anesthetics chronic pain history history of hepatic, neuromuscular, cardiac and/or renal failure infection at the injection site