Inclusion Criteria:  positive for SARS-CoV-2 by the RT-PCR method, in common bed for minimum of 1 day and maximum of 5 days, ensuring that patients are no more than 10 days since showing the first symptoms, who are positive for SARS-CoV-2 in the first collection of oral fluid and saliva, and who demands oral hygiene care and other preventive and therapeutic dental procedures.  Exclusion Criteria:  pediatric patients, t hose who tested negative for SARS-CoV-2 by the RT-PCR method at the time of recruitment or at the time of first oral fluid and saliva collection; those who exhibit oral ulcerations and other erosive lesions in the oral mucosa, which contraindicate the use of cetylpyridinium; patients who have bleeding in the oral cavity which prevents sample collections; patients who report history of allergy, irritations or other side effects derived from the use of these substances; patients who do not adhere to oral care protocols or those in whom it was not possible to perform these procedures.