Inclusion Criteria:  Healthy subjects of 2 months (minimum 6 weeks), 3 months , 7 months and above; Willing to provide proof of identity; Without vaccination history of pneumococcal vaccine; None-pregnancy or do not plan to pregnancy recently;; Volunteers of 18 years old and above who have the ability to understand clinical studie progress and sign informed consent; Volunteers of 8-17 years old and their guardians who willing sign informed consent; Able to understand and sign the informed consent by their guardians or trustees for the volunteers of 8 years old and below; Able and willing comply with the requirements of the protocol  Exclusion Criteria:  Volunteers whose axillary body temperature was >37.0# before vaccination Volunteers who suffered from Congenital malformation or developmental disorder, genetic defect, severe malnutrition, etc; Volunteers who has a history of epilepsy, convulsions or psychosis; Allergic person; Any prior administration of blood products in last 3 month; Any prior administration of other research medicines in last 1 month; Plans to participate in or is participating in any other drug clinical study; Any prior administration of attenuated live vaccine in last 14 days; Any prior administration of subunit or inactivated vaccines in last 7 days; Had fever before vaccination, Volunteers with temperature >37.0°C on axillary setting; According to the investigator's judgement, the subjects have any other factors that make them unfit to enroll the clinical trial