Inclusion Criteria:  Patient with standard indications for an electrophysiology study and/or catheter ablation per European Heart Rhythm Association/Heart Rhythm Society) guidelines and/or judgement of the investigator Age 18 to 80 Signed Informed Consent Form  Exclusion Criteria:  Any cardiac surgery, myocardial infarction, percutaneous coronary intervention/percutaneous transluminal coronary angioplasty, or coronary artery stenting which occurred during the 90-day interval preceding the date that participant signed the Informed Consent Form Unstable angina NHYA class III or IV congestive heart failure and/or known left ventricular ejection fraction less than 45% Thrombocytosis, thrombocytopenia Contraindication to anticoagulation therapy Active systemic infection Cryoglobulinemia Known reversible causes of arrhythmia Any cerebral ischemic event (stroke or transient ischemic attacks) which occurred during the 180-day interval preceding the date the participant signed the Informed Consent Form, or any known unresolved complications from the previous stroke/transient ischemic attack Pregnancy Unwilling or unable to comply fully with study procedures