Inclusion Criteria:  Individuals who have recently undergone surgery or injury requiring inactivity  Exclusion Criteria:  Cardiac abnormalities considered exclusionary by the study physician (congestive heart failure, coronary artery disease, right-to-left shunt) Uncontrolled endocrine or metabolic disease Glomerular filtration rate < 45 mL/min/1.73 m^2 or evidence of kidney disease or failure Vascular disease or risk factors of peripheral atherosclerosis Risk of deep vein thrombosis including family history of thrombophilia, pulmonary emboli, deep vein thrombosis Use of anticoagulant therapy Elevated systolic pressure > 180 or a diastolic blood pressure > 110 Implanted electronic devices such as pacemakers, infusion pumps, stimulators Cancer or history of successfully treated cancer (less than 1 year) other than basal cell carcinoma Currently on a weight-loss diet or body mass index > 35 kg/m^2 Inability to abstain from smoking for duration of study History of > 20 pack per year smoking Positive for human immunodeficiency virus, hepatitis B or hepatitis C Recent anabolic or corticosteroids use (within 3 months) Subjects with hemoglobin or hematocrit lower than accepted lab values Agitation/aggression disorder History of stroke with motor disability Recent history (< 12 months) of gastrointestinal bleed Depression diagnosis Alcohol or drug abuse Liver disease (AST/ALT 2 times above the normal limit, hyperbilirubinemia) Respiratory disease (acute upper respiratory infection, history of chronic lung disease with resting oxygen saturation < 97% on room air) Pregnancy