Inclusion Criteria:  Healthy volunteers who fully understand the purpose, content, benefits and possible adverse reactions of the test and voluntarily sign written informed consent prior to the commencement of any test-related activities. Healthy males, aged 18 to 45 years (including 18 and 45 years). Male subjects weighed 45-100 kg (including 45 and 100 kg), body mass index (BMI) was 19.0-25.0 kg/m2 (including 19.0 and 25.0 kg/m2), where BMI = body weight (kg)/height2 (m2). The subject agrees to use reliable contraceptive methods (such as abstinence, sterilization, birth control pills, injectable contraceptive meprogesterone or subcutaneous implantation) for himself and his partner during the study period and for 6 months after the infusion of study drugs.  Exclusion Criteria:  History of hypertension or abnormal blood pressure at screening/baseline [SBP >140 mmHg and/or diastolic blood pressure >90 mmHg confirmed by one repeat measurement on the same day]; Clinically significant proteinuria examination or history of proteinuria assessed by the investigator; Abnormal physical examination or examination results (e.g., chest X-ray, laboratory examination) are considered clinically significant by the investigator; Have received any antibody or protein drug or small molecule targeted drug therapy targeting VEGF or VEGF receptor in the past 1 year; Use of any biological product or live viral vaccine within 3 months prior to drug infusion, or use of any monoclonal antibody within 12 months; Have hereditary bleeding tendency or coagulopathy, or have a history of thrombosis or bleeding; History of digestive tract perforation or fistula; Unhealed wounds, ulcers or fractures, or those who had undergone major surgery within the previous 2 months or were expected to undergo major surgery within the study period or 2 months after the end of the study; Use a prescription or over-the-counter drug or nutraceutical product within the 5 half-life of the drug or nutraceutical product or within 2 weeks prior to use of the study drug, whichever is longer. Herbal supplements should be discontinued 28 days prior to use of the study drug; Hepatitis B virus surface antigen (HBsAg), hepatitis C virus (HCV) antibody, human immunodeficiency virus (HIV) antibody, or treponema pallidum antibody test positive; Known allergy to bevacizumab or any of its excipients; Known history of allergic diseases or allergies; People with a history of severe allergy, allergy to protein products, rat-derived products and related ingredients of experimental drugs; Blood donation history within 3 months prior to drug infusion; Has received any other investigational drug treatment or participated in another interventional clinical trial within 3 months prior to screening; History of alcohol or drug abuse in the 12 months prior to screening; Subjects were unable to abstain from alcohol within 72 hours prior to administration and throughout the trial; A history of mental illness; Have pregnancy plans during the trial ; Unable to complete the study according to protocol requirements during the study; Conditions considered unsuitable for inclusion by other researchers.