Inclusion Criteria:  Age between 18 and 60 years Documented HIV-1 infection Stable antiretroviral therapy at least 6 months before enrollment Viral suppression Metabolic syndrome , defined by Adult Treatment Panel-III criteria No previously known kidney or liver disease Signed informed consent  Exclusion Criteria:  People younger than 18 years and older than 60 years Prior atherosclerotic cardiovascular disease Diabetes mellitus type 1 or 2 Previous use of glucose and/or lipid modifying medications Pregnancy Withdrawal of informed consent