Inclusion Criteria:  KRAS/NRAS mutated (G12D or G12R) solid tumor Positive for circulating tumor DNA (ctDNA) despite prior standard therapy including surgery and chemotherapy/radiation therapy where applicable Screening CT is negative for recurrent disease Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1  Exclusion Criteria:  Presence of tumor mutations where specific therapy is approved, and the patient is able to receive the approved therapy Known brain metastases Use of immunosuppressive drugs