Inclusion criteria:  Male or female participants with minimum 40 years of age. A diagnosis of COPD confirmed by spirometry (According to Global initiative for chronic obstructive lung disease [GOLD] 2019 criteria) in Tier 2 and Tier 3 hospitals. In hospitalized participants, recruit only participants who receive any intravenous therapy. A signed and dated written informed consent. Participants can communicate normally.  Exclusion criteria:  Current primary diagnosis of asthma, active tuberculosis, bronchiectasis, lung cancer or other active pulmonary disease. Other unstable diseases or cognitive behavior, which could influence CAT and lung function results (judged by physicians). Experienced a moderate/severe COPD exacerbation treated by a physician within last 1 month. Currently participating in another COPD clinical study, which provides the participant investigational medication and/or disease management.