Inclusion Criteria:  • Informed consent  Age ≥ 18 years Previous acute coronary syndrome with percutaneous coronary revascularization Baseline EF > 40% At least 12 months of follow-up  Exclusion Criteria:  • Significant valvular heart disease (greater than mild stenosis or moderate regurgitation) before ACS  Type 1, 3, 4, 5 pulmonary hypertension (14) before ACS Constrictive pericarditis before ACS Primary or infiltrative cardiomyopathies Heart transplantation Medical therapy with loop diuretics for heart failure before ACS Previous hospitalizations for heart failure or clinical sign of heart failure detected outpatient before ACS