Inclusion Criteria:  Male, aged ≥ 18 years. WHO performance status 0,1, or 2. Written informed consent. Histopathologically confirmed adenocarcinoma of the prostate Increased risk of nodal metastases according to the MSKCC nomogram (> 7%) Scheduled for surgical (laparoscopic) prostatectomy including ePLND- Suitable for RP and ePLND, as per institutional guidelines  Exclusion Criteria:  Prostate cancer patients with prior abdominal or inguinal surgery History of allergy to iodine, food or medicinal induced urticaria, asthma, eczema, or aller-gic rhinitis Hyperthyroid or thyroidal adenoma Kidney insufficiency History of oversensitivity to FLUORESCITE composites Patients using beta-blockers