Inclusion Criteria:  Patients on an extracorporeal life support system with heart failure:  Implantation of intravenous ECMO Hemodynamic support with vasopressors and/or tonics; Procalcitonin level ≥ 1 ng/ml; Invasive hemodynamic monitoring; Written informed consent.  Patients on an extracorporeal life support system with pulmonary failure:  IV ECMO implantation High levels of venous and arterial CO2 (CO2> 50 mmHg), Low paO2, SvO2, SpO2. Invasive hemodynamic monitoring;  Written informed consent.  -Patients with left ventricular assistive device implantation:  LVAD implantation Biventricular heart failure IV INTERMACS I-III Hemodynamic support with vasopressors and/or tonics; Procalcitonin level ≥ 0.1 ng/ml; Invasive hemodynamic monitoring;  Written informed consent.  -Patients in operations with prolonged artificial circulation, hypothermia and circulatory arrest:  Hemodynamic support with vasopressors and/or tonics; Bypass duration> 120 minutes Hypothermia ≤ 25 0С Circulatory arrest Procalcitonin level ≥ 1 ng/ml; Invasive hemodynamic monitoring; Written informed consent.  Exclusion Criteria:  Patients on an extracorporeal life support system with heart failure:  Age less than 18 years old Terminal hepatic or renal failure just before the procedure Patient's written refusal to participate in the study  Patients on an extracorporeal life support system with pulmonary failure:  Age less than 18 years old Terminal hepatic or renal failure just before the procedure Patient's written refusal to participate in the study  Patients with left ventricular assistive device implantation:  Age less than 18 years old Acute hepatic or renal failure just before the procedure Patient's written refusal to participate in the study  Patients in operations with prolonged artificial circulation, hypothermia and circulatory arrest:  Age less than 18 years old Terminal hepatic or renal failure just before the procedure Patient's written refusal to participate in the study