Inclusion Criteria:  Patients fully understand and voluntarily participate in this study and sign informed consent; Aged 18-65 years, without gender limitation; Histologically or cytologically confirmed advanced solid tumors; Patients with advanced solid tumors who have been judged by the investigator to be ineffective with conventional therapy or lacking effective treatment, including those for whom no current standard of care is available or for whom is unable to tolerate standard therapy, etc.; At least one measurable lesion according to RECIST v1.1 at baseline; Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1; AEs from the previous treatment have resolved to ≤ Grade 1 based on CTCAE (except for the toxicity without safety risk judged by the investigator, such as alopecia, hyperpigmentation);  Adequate organ function defined as:  Absolute neutrophil count (ANC) ≥1.5*109/L (No G-CSF treatment within 2 weeks prior to the laboratory test); Hemoglobin ≥ 90 g/L (No red blood cell transfusion within 2 weeks prior to the laboratory test); Platelet count ≥ 100*109/L (No platelet transfusion within 2 weeks prior to the laboratory test); Creatinine ≤1.5 upper limit of normal (ULN); Total bilirubin ≤1.5 ULN; Aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) ≤ 3 ULN; Coagulation: prothrombin time (PT) or International Normalization Ratio (INR) ≤1.5 ULN Female patients must have a urine or blood HCG negative test before enrolment (except for menopause and hysterectomy); Patients and their partners must agree to use effective contraceptives measures during the study until 6 months after the end of the last dose.  Exclusion Criteria:  History of severe allergy to mitoxantrone hydrochloride or any excipients of the study drug; Cerebral or meningeal metastases; Life expectancy < 3 months; Patients with chronic hepatitis B (HBsAg or HBcAb positive with HBV DNA ≥ 1000 IU/mL), chronic hepatitis C (HCV antibody positive with HCV RNA above the lower limit of detection of the study center), or human immunodeficiency virus (HIV) antibody positive; Active bacterial, fungal or viral infections that require intravenous infusion treatment within 1 week prior to the first dose; Any anticancer treatment within 4 weeks prior to the first dose (e.g., radiotherapy, targeted therapy, immunotherapy, endocrine therapy, etc.); Traditional Chinese medicine or proprietary Chinese medicine with an approved oncology indication within 2 weeks prior to the first dose; Enrolled in any other clinical trials within 4 weeks prior to the first dose; Patients underwent major surgery within 3 months prior to the first dose did not fully recover, or have a surgical schedule during the study period; Serious thrombosis or thromboembolism as judged by the investigator within 6 months prior to screening; History of additional malignant tumor within 3 years, except for locally curable cancer that has been cured, such as basal or squamous cell skin cancer or in situ prostate, cervical or breast cancer;  Patients with the following cardiac function defects:  Long QTc syndrome or QTc interval > 480 ms; Complete left bundle branch block, II-III degree atrioventricular block; Severe, uncontrolled arrhythmias requiring pharmacological treatment; History of chronic congestive heart failure, NYHA ≥ grade 3; Cardiac ejection fraction < 50% within 6 months prior to screening; Heart valve disease with CTCAE ≥ grade 3; Uncontrollable hypertension (defined as a measured systolic blood pressure ≥ 160 mmHg or diastolic blood pressure ≥ 100 mmHg under pharmacological control); ECG evidence of myocardial infarction, unstable angina, history of severe pericardial disease, and acute ischemic or severe conduction system abnormalities within 6 months prior to screening; Previous treatment with adriamycin or other anthracyclines, with the total cumulative dose (doxorubicin equivalent) >350 mg/m2; Lactating female; Serious and/or uncontrolled medical condition that, in the judgment of the investigator, may affect the patient's participation in this study (including, but not limited to: diabetes not effectively controlled, kidney disease requiring dialysis, severe liver disease, life-threatening autoimmune and bleeding disorders, substance abuse, neurological disorders, etc.); Not suitable for this study as decided by the investigator due to other reasons.