Inclusion Criteria:  Patient ≥ 18 years old 1st or 2nd kidney transplant Transplantation from a deceased donor (Encephalic death or arrested heart Maastricht III) C0 / D ratio <1.05 at one month of kidney transplant Renal graft function <60ml / min (eGFR estimate by CKD-EPI or MDRD).  Exclusion Criteria:  Patient ≤ 18 years old, under guardianship or protected Graft rank ≥ 3 Renal graft function <30 ml / min (eGFR estimate by CKD-EPI or MDRD) Presence of pre-transplant DSA (threshold> 2000 MFI) Occurrence of histologically proven rejection during the 1st month of transplant Presence of another functional transplant (heart / lung / liver / pancreas) or kidney bi-transplant Transplantation from a living donor Transplantation from an arrested heart donor Maastricht II