Inclusion Criteria:  Patient Inclusion Criteria:  Male or female, aged 9 years and above Has facial non-nodular AV with IGA score of moderate or severe Considered as a potential candidate for sarecycline (Seysara®) treatment, per clinician judgment  Caregiver Inclusion Criteria:  Primary caregiver of the study-eligible patient Male or female, aged 18 years and above  Exclusion Criteria:  Patients with any known resistance to other tetracyclines Patients with any dermatological or physical condition of the face that could interfere with the AV clinical evaluations. Patients with any history of allergy to tetracycline-class antibiotics, pseudomembranous colitis or antibiotic-associated colitis. Unable to comply with the requirements of the study or patients who in the opinion of the Site Investigator should not participate in the study  Other protocol defined Inclusion/Exclusion criteria may apply