Inclusion Criteria:  patients 18 years of age and over diagnosis of RA according to EULAR/ACR 2010 classification criteria active RA: DAS28-CRP ≥ 3.2 insufficient response despite a stable DMARD treatment (cDMARD/tsDMARD(targeted synthetic DMARD)/bDMARD) ≥ 12 weeks stable dose of corticosteroids for at least 4 weeks prior to inclusion patient able to understand the objectives and risks of the study and to provide a written informed consent to participate in the study, dated and signed before initiating any trial-related procedure patient having been informed about the results of the preliminary medical visit  if woman of childbearing, they should have no desire to procreate for the duration of their participation in the study, agreeing to use an effective contraception method* during the study and until 5 days following the last visit or last dose of treatment in case of early stop; acceptable birth control methods:  *progestogen-only oral hormonal contraception, where inhibition of ovulation is not the primary mode of action *male or female condom with or without spermicide *cap, diaphragm or sponge with spermicide *a combination of male condom with either cap, diaphragm or sponge with spermicide (double barrier methods) are also considered acceptable, but not highly effective, birth control methods affiliation to a social security regime  Exclusion Criteria:  severe or acute renal insufficiency, defined by eGFR < 30 mL/min hyperkalemia, with K+ > 5,1 mmol/L end-stage liver failure, cirrhosis hypersensitivity to the active ingredients, to sulfonamides or intolerance to any of the excipients including lactose Addison's disease patient currently being treated with spironolactone, or previous spironolactone treatment in the last 3 months concomitant treatment with mitotane, other potassium-sparing diuretics (alone or in combination) such as amiloride, potassium canrenoate, eplerenone, triamterene other inflammatory arthritis except associated Sjögren's syndrome pregnancy (women of childbearing potential : positive blood pregnancy test at the inclusion visit (V0)) breastfeeding participation in a clinical study with an investigational product within 4 weeks prior to the start of the study treatment or still under the exclusion period unwillingness or incapacity to adhere to study protocol (language barriers, cognitive disorders, etc.). subjects who are compulsorily detained for treatment of either a psychiatric or physical (e.g., infectious disease) illness. patient who cannot be followed for 6 months patient over the age of legal majority who are protected, or deprived of liberty by judicial or administrative decision (vulnerable subjects)