Inclusion Criteria:  Individuals of 18 years of age and older Patient with PaO2 <60 mmHg, SO2 <89% and dyspnea. Patients with home oxygen therapy enrolled in-home care programs during the study period. Time of evolution of the disease greater to one year Patients who express their willingness to participate in the study through their informed consent.  Exclusion Criteria:  Patients with the following exceptional situations will be excluded from the study:  Patients with invasive and/or non-invasive mechanical ventilation Patients with the inability to operate a mobile application or those who do not have a smartphone with an operating system (Android or iOS) and available data connection.