Inclusion Criteria:  Adults aged ≥18 years Admitted to ICU on ECMO support Positive influenza or SARS-CoV-2 PCR from nasal, throat swab, BAL or other respiratory specimen. Positive invasive aspergillosis infection (positive Aspergillus species culture from respiratory specimen or positive serum galactomannan) or strong clinical suspicion of invasive aspergillosis infection based on symptoms, CT, CXR.  Exclusion Criteria:  No participants < 18 years of age Not requiring ECMO support No positive influenza or SARS-CoV-2 results Any other significant disease or disorder which, in the opinion of the Investigator, may either put the participants at risk because of participation in the trial, or may influence the result of the trial, or the participant's ability to participate in the trial.