Inclusion Criteria:  Treatment with any of the following antibiotics; cefiderocol, ceftazidim-avibactam, ceftolozan-tazobactam, fosfomycin, meropenem-vaborbactam or imipepenem-relebactam against an acute infection.  Exclusion Criteria:  Ongoing treatment with any of the above mentioned antibiotics for more than seven days at the point of inclusion.