Inclusion Criteria:  Male or female above 18 years old; Have stable or unstable angina symptoms, or need to measure FFR after acute myocardial infarction; The subjects knew about the experiment and signed the informed consent voluntarily.  Exclusion Criteria:  People is considered not suitable for a diagnostic intervention by the researcher determines; Myocardial infarction within 6 days; Left ventricular ejection fraction(LVEF)≤50%; eGFR<60ml/min（1.73m²） Severe coagulation dysfunction or hemorrhagic disease; Allergic to iodine contrast agent or adenosine, or not suitable for adenosine; Having participated in other clinical trials within 1 months; Other situations that the researchers judged were not suitable for inclusion.