Key Inclusion Criteria:  Age 21 to 75  Biopsy-confirmed NASH with fibrosis stage F2 or F3 per NASH CRN System and NAS ≥4, with a score of at least 1 in each of steatosis, ballooning degeneration, and lobular inflammation.  Qualifying biopsy must be either within 6 months of screening visit or obtained during screening period  Key Exclusion Criteria:  Have poorly controlled high blood pressure Have type 1 diabetes or poorly controlled type 2 diabetes. History of cirrhosis or evidence of cirrhosis by clinical, imaging or liver biopsy evaluation Are planning to try to lose weight during the conduct of the study. Have a BMI <25 kg/m2  Other inclusion and exclusion criteria may apply.