Inclusion Criteria:  Patients aged 18 years and older. All patients fulfilled the 2010 American College of Rheumatology (ACR)/the European League Against Rheumatism (EULAR) classification criteria.  Patients are willing to accept CM therapies defined as Chinese herbal medicine, Chinese patent medicine, external treatment, acupuncture and moxibustion, etc  Exclusion Criteria:  Patients who refuse informed consent.