Inclusion Criteria:  Volunteers over the age of 18 Patients who had no significant medical diseases or use of drugs, were not pregnant, had no allergy, and did not smoke. Patients who had bilateral asymptomatic vertical third molar teeth with impaction of class I, level C according to Pell and Gregory Classification, and no history of recent antibiotic or anti-inflammatory treatment.  Exclusion Criteria:  Patients who had symptomatic impacted third molars. Patients who had a medical history described above. Patients under the age of 18.