Inclusion Criteria:  Male or female aged 20-50 years, inclusive. Systemically and ophthalmologically healthy subjects evaluated during the clinical history. Best-corrected visual acuity (BCVA) 20/40 or better in both eyes. Negative Fluorescein staining in Fluorescein Corneal staining (FCS) in both eyes. Up to 0.5 Conjunctival redness in Conjunctival redness without slit lamp, in standardized lighting conditions, in both eyes. IOP (< 22mmHg), in both eyes. No pathology findings in Slit-lamp biomicroscopy in both eyes. Ability to comply with the requirements of the study and complete the questionnaire and a full sequence of protocol-related evaluations. Ability to understand and provide written informed consent. In the judgement of the investigator, the participant can safely perform study activity.  Exclusion Criteria:  Have chronic systemic disease of any form known. In the case of women: be pregnant, breastfeeding or planning to become pregnant within the study period or women without a history of hysterectomy, oophorectomy, who do not ensure a hormonal contraceptive method or intrauterine device during the study period. Be a user of topical ophthalmic products of any kind. Being a chronic drug user. Be a user of contact lenses. Have a history of any type of eye surgery. Participating in clinical research studies 90 days prior to inclusion in the present study. In the judgement of the investigator, any condition that could interfere with the intent of the study or would make participation not in the best interest of the participant.