Inclusion Criteria:  Adults, 18 years and older Upper limb impairment caused by brachial plexus injury (BPI), any stroke (CVA), spinal cord injury (SCI), or other neurological diagnoses Be medically stable Be in the process of being fit with a MyoPro as a first-time user Has at least trace muscle activation in the elbow and wrist flexors and extensors as measured by a 1/5 on a manual muscle test at targeted joints Has the minimum microvolt EMG threshold to operate the MyoPro, such that the individual can sustain the EMG signals above the threshold for two full seconds (both at elbow and hand) for a minimum of three times within three minutes Has passive range of motion within 5 degrees of terminal range for finger open and close Has passive range of motion within 5 degrees of terminal range for wrist flexion and at least neutral for wrist extension Has passive range of motion within 5 degrees of terminal range for elbow flexion and extension Has at least 30 degrees of active range of motion for shoulder flexion or shoulder abduction Able to support the weight of the MyoPro Able to tolerate functional tasks for 20 min with intermittent rests without excessive fatigue Has intact cognition Able to clearly and verbally communicate in the English language Has a wireless internet connection to participate in telehealth sessions Be attending therapy within four weeks of getting fit and trained with a MyoPro  Exclusion Criteria:  Has a body weight above 235 lbs Upper limb measurements will not allow for correct fit of the orthosis. Fixed upper limb contractures on affected side Unable to have full passive finger opening when the wrist is in neutral Severe spasticity or tone defined as 2 or higher at the wrist or fingers, or 3 or higher at the elbow on the Modified Ashworth Spasticity Scale Severe shoulder subluxation (greater than one finger with significant pain) or shoulder dislocation Passive shoulder range of motion less than 45 degrees in flexion and abduction Excessive pain, hypersensitivity, or skin issues in the arm(s) that would prevent wearing the MyoPro Severe cognitive or psychiatric problems that might be contraindicated for training and safe MyoPro use Bilateral upper limb impairment Pregnancy Other conditions (e.g. history of neurological disorder other than SCI, BPI, or CVA) or circumstances that would preclude safe and/or effective participation, including severe sensory deficits, skin conditions, and/or other sequelae that may be contraindicated for myoelectric MyoPro use