Inclusion Criteria:  Patients age ≥ 18 years Persistent atrial fibrillation Unknown symptom burden related to AF  Exclusion Criteria:  Known left-atrial appendage thrombus Prior catheter or surgical ablation for AF Intolerance or contraindication to Amiodarone Contraindication to appropriate anticoagulation Patient is included in another randomized clinical trial Patient is unable or unwilling to provide informed consent Patient with a history of noncompliance with medical therapy Patient does not meet all of the above listed inclusion criteria Pregnancy (all women of child bearing age and potential will have a negative BHCG test before enrolment) Breastfeeding Patients for whom the investigator believes that the trial is not in the interest of the patient