Inclusion Criteria:  Subjects are eligible to be included in the study only if all of the following criteria apply:  Ability to understand and comply with study procedures and give written informed consent Following the diet and lifestyle recommendations at least 12 weeks prior to the treatment period Males or post-menopausal females Aged ≥18 years at the time of informed consent Fasting serum TG levels ≥200 mg/dL (≥2.26 mmol/L) and ≤500 mg/dL (5.65 mmol/L) at screening Serum HDL-C <50 mg/dL (<1.30 mmol/L) if male or <55 mg/dL (<1.42 mmol/L) if female at screening.  Exclusion Criteria:  Subjects are excluded from the study if any of the following criteria apply:  Current or planned use of any lipid-altering medications other than the study drugs, statins, or ezetimibe during the study.  i. Subjects currently on statins or ezetimibe must be at high risk for atherosclerotic CV diseases, and the dose(s) must be stable for at least 4 weeks prior to screening  ii. For subjects currently on lipid-altering medications other than statins or ezetimibe, at least 4-week washout period (or for subjects currently on probucol at least 8 week washout period) will be required prior to the first fasting blood sampling at Screening Visit  Type 1 diabetes mellitus or poorly controlled Type 2 diabetes mellitus defined by HbA1c (NGSP level) ≥8.0% at screening Uncontrolled hypertension defined by seated systolic blood pressure ≥160 mmHg and/or diastolic blood pressure ≥100 mmHg at screening Uncontrolled thyroid disorder Creatinine ≥1.5 mg/dL at screening Severe hepatic disorder defined as cirrhosis of Child-Pugh class B or C, or AST or ALT >2 × ULN at screening History of pancreatitis Gallbladder disorder, history of cholelithiasis, primary biliary cirrhosis, or history of disease or surgery that may affect the absorption, distribution, metabolism and excretion of drugs or the metabolism of bile salts Unexplained creatine kinase (CK) >5 × ULN at screening Myocardial infraction or stroke (including transient ischemic attack) within 3 months prior to the informed consent New York Heart Association Class III or IV heart failure History of malignancy within 5 years Participation in another clinical study at the time of informed consent or administration of an investigational drug other than placebo within 16 weeks prior to the informed consent for this study