Inclusion Criteria:  Traumatic brain injury Spontaneous intracranial hemorrhage Ischemic stroke An anticipated stay in the neuro-ICU for 48 hours or longer.  Exclusion Criteria:  Persistent coma defined as Richmond Agitation-Sedation Scale (RASS) -5 to -3 throughout the neuro-ICU stay Congenital brain injury Suspected pre-existing Cognitive impairment (Informant Questionnaire on cognitive decline in the elderly (IQCODE): 3.3 or more) (regardless of cause) Permanent residence outside Denmark Inability to communicate in Danish