Inclusion Criteria:  Not applicable as this study is on samples from a biobank. The inclusion criteria for the "GrossPath" cohort were: pregnant women followed at Nîmes University hospital for normal pregnancy or pregnancy with placental vascular pathology (pre-eclampsia and/or intra-uterine growth retardation). The patient must have given her free and informed consent and signed the consent form. The patient must be a member or beneficiary of a health insurance plan Only women are included Patients are at least 18 years old  Exclusion Criteria:  Not applicable as this is a study on samples from a biobank. The non-inclusion criteria of the "GrossPath" cohort were : twin pregnancies.