Inclusion Criteria:  Patients with no history of the thorax and abdominal abnormalities confirmed through an imaging test requested for healthcare purposes in the last twelve months (e.g., thorax X-ray and abdominal ultrasound or thorax and abdominal CT) Patients who undergo EUS assessment due to chronic dyspepsia.  Exclusion Criteria:  Morphological alteration on at least one mediastinal and abdominal organ/anatomic strictures documented through any imaging test or EUS. Uncontrolled coagulopathy, kidney/liver failure, or any comorbidity with a meaningful impact on cardiac risk assessment (NHYA III/IV); Refuse to participate in the study or to sign corresponding informed consent.