Inclusion Criteria:  Children (<18) of both genders undergoing cancer chemotherapy Symptomatic SARS-CoV-2 infection, confirmed by (positive PCR test). Patients with hematologic malignancies (ALL, AML, HL & NHL) on active treatment or under follow up < 3 months from end of treatment protocol  Exclusion Criteria:  Children (<18 years) of both genders undergoing cancer chemotherapy with (PCR negative) test result for SARS-CoV-2. Children who are PCR positive but are diagnosed with an immune disorder that may confound the study results.