Inclusion Criteria:  (1) Case group a) Aged 25-75 years. b) Han nationality. c) Patients with cervical cancer or cervical precancerous lesions above CIN2 diagnosed by biopsy or postoperative pathological diagnosis. (2) Control group: a) Aged 25-75 years. b) Han nationality. c) No family history of cervical cancer or precancerous lesions. d) The results of TCT examination showed no abnormality.  Exclusion Criteria:  (1) suffering from other neoplastic diseases. (2) pregnant women. (3) those with a history of bone marrow transplantation.