Inclusion Criteria:  healthy adult subjects who signed informed consent Body Mass Index(BMI)=18.5~29.9kg/㎡  Exclusion Criteria:  Subjects participated in another clinical trial within 6 months prior to administration of the study drug Inadequate subject for the clinical trial by the investigator's decision Upper Limits of Normal x 1.5 < Aspartate transaminase(AST), Alanine transminase(ALT), Total bilirubin