Inclusion criteria (patient category):  Able and willing to give written informed consent Male and female subjects with age >18 years  A diagnosis of HFpEF based on typical symptoms (and/or signs), a LVEF >50% (assessed within 12 months prior to baseline testing) and at least two of the following criteria10:  For BMI <35.0 kg/m2: NT pro-BNP ≥220 pg/mL For BMI ≥35.0 kg/m2: NT pro-BNP ≥125 pg/mL Left atrial volume index >34 ml/m2 or Left ventricular mass index >115g/m2 (men) or >95g/m2 (women) E/e' ≥13 or e' average <9 cm/s BMI <25 or >30  Exclusion criteria for patient category:  Amyloid cardiomyopathy or cardiomyopathy due to sarcoïdosis or M. Fabry, as reflected by medical history. Atrial fibrillation on ECG performed at screening Genetic hypertrophic (obstructive) cardiomyopathy. Severe (grade III/III) aortic stenosis. Female patient with childbearing potential, aiming to get pregnant or pregnant at the time of inclusion. Patients on (intermittent or continuous) hemodialysis Proven hypersensitivity to iodine contrast or any other contra-indication for computed tomography.  Inclusion criteria for healthy controls:  Able and willing to give written informed consent Male and female subjects with age >18 years BMI <25 or >30  Exclusion criteria for healthy controls:  Diagnosis of any cardiovascular disease, either in the medical history or diagnosed during screening. Diagnosis of diabetes mellitus, defined as use of glucose lowering drugs Diagnosis of hypertension, defined as mean of 3 blood pressures measurements of >140/90 mmHg at screening or use of blood pressure lowering drugs. Female patients with childbearing potential, either already pregnant or aiming to get pregnant at the time of inclusion. Proven hypersensitivity to iodine contrast or any other contra-indication for computed tomography.