Inclusion Criteria:  Patient requiring endoscopic explorations for screening or follow-up in the context of a suspected IBS or IBD or colorectal cancer Or Patient with IBD requiring surgical management Patient over 18 years old Patient able to read and understand the information leaflet Patients who have given their consent to participate in the study Patients affiliated to a social security system (including AME)  Exclusion Criteria:  Patients who have received antibiotic treatments in the 10 days preceding endoscopic exploration Pregnant or breastfeeding patients Patients under 18 years old Patients under guardianship or curatorship Patients unable to sign a free and informed consent