Inclusion Criteria:  Male or female, with clinical indication for blood glucose measurement Signed informed consent form Minimum age of 18 years Subjects are legally competent and capable to understand character, meaning and consequences of the study.  Exclusion Criteria:  Pregnancy or lactation period Severe acute disease (at the study physician's discretion) Severe chronic disease with inherent risk of aggravation by the procedure (at the study physician's discretion) Current constitution that compromises the subject's capability to participate in the study (at the study physician's discretion) A current constitution that does not allow participating in the study (e.g. hematocrit out of BGM specifications, medication known to influence blood glucose measurements; see Appendix A of ISO 15197) Being unable to give informed consent < 18 years Legally incompetent