Inclusion Criteria:  Presence of traumatic spine lesion (with and without spinal cord injury) Requiring invasive mechanical ventilation, via oro-tracheal or tracheostomy tube, 16 years of age or older Patient or substitute decision maker able to provide consent  Exclusion Criteria:  Expected withdrawal of treatments within 24 hours of screening Chronic respiratory failure already treated with mechanical ventilation before the injury Documented pre-existing neuromuscular diseases