Inclusion Criteria:  female, Han nationality; right-handed; meet the diagnostic criteria of DSM-5 bulimia nervosa, body mass index (BMI) ≥ 18.5kg / m2; education level of junior high school or above, sufficient audiovisual level to complete the necessary examination of the study. Before entering the group, he has received fluoxetine treatment, the dose has been stable for one month, and has not received any form of physiotherapy (such as electroconvulsive therapy) within one month; each patient must understand the nature of this study and sign an informed consent form.  Exclusion Criteria:  Patients who meet the diagnosis of DSM-5 other than BN, such as substance abuse / dependence, bipolar disorder, high risk of suicide, strong destructive impulses or antisocial behaviors; complicated with severe organic diseases and cognitive impairment, make it impossible for patients to complete the required symptom assessment and psychological tests; have a history of brain trauma or brain disease, epilepsy, etc. Those who have been exposed to ECT or MECT within 1 month; those with intracranial metal materials or pacemakers, implanted metal objects in vivo; those who are pregnant or planned pregnancy, women of childbearing age who are positive in pregnancy test.