Inclusion Criteria:  Male or female, between the ages of 18 - 30 years (inclusive) Have a body mass index (BMI) between 18-30 kg·m2 (inclusive) Be in general good health as assessed by a general health questionnaire Non-smoking Regular menstrual cycle and not using hormonal contraceptives Willing and able to provide informed consent  Exclusion Criteria:  Currently using analgesic or anti-inflammatory drugs A history of neuromuscular problems or muscle and/or bone wasting diseases Any acute or chronic illness, metabolic disorders Currently using corticosteroids Use of hormonal contraceptives or anabolic steroids (e.g. testosterone)