Inclusion Criteria:  Patients with a confirmed histologic diagnosis of head and neck cancer Patients referred to non-palliative radiotherapy to the oral cavity will be included in the study Synchronous or induction chemotherapy, or both, will be permitted. Patients aged over 18, Patients able to provide informed consent, Patients having radiotherapy for at least three weeks (lower limit has been set at 50 Gy), Patients able to complete records accurately  Exclusion Criteria:  Patients with a confirmed and medically treated diabetes mellitus, Patients with allergy to honey, thyme or any other ingredient, Patients who will refuse to take part in this study and Patients with previous radiotherapy or presence of systemic disease.