Inclusion Criteria:  Male Age 45 to 80 years, with >10 years life expectancy Biopsy-confirmed, NCCN (favorable and unfavourable) intermediate-risk prostate acquired within last 12 months Stage ≤T2c, N0, M0 ISUP Grade Group 2 or 3 disease on TRUS-guided biopsy or in-bore biopsy PSA ≤20ng/mL within last 3 months Treatment-naïve Planned ablation volume is < 3 cm axial radius from urethra on mpMRI acquired within last 6 months  Exclusion Criteria:  Inability to undergo MRI or general anesthesia Suspected tumor is > 30 mm from the prostatic urethra Prostate calcifications is > 3 mm in maximum extent obstructing ablation of tumor Unresolved urinary tract infection or prostatitis History of proctitis, bladder stones, hematuria, history of acute urinary retention, severe neurogenic bladder Artificial urinary sphincter, penile implant, or intraprostatic implant Patients who are otherwise not deemed candidates for radical prostatectomy Inability or unwillingness to provide informed consent History of anal or rectal fibrosis or stenosis, or urethral stenosis, or other abnormality challenging insertion of devices