Inclusion Criteria:  Subject must provide written informed consent prior to any clinical investigation related procedure. Be ≥ 18 years old. Patients with controlled type 1 or type 2 Diabetes Mellitus.  Exclusion Criteria:  Subject is currently participating in another clinical investigation or has participated in another clinical investigation in the past 30 days prior to the start of the present study Pregnant or nursing subjects and those who plan pregnancy during the clinical investigation follow-up period Presence of other anatomic or comorbid conditions, or other medical, social, or psychological conditions that, in the investigator's opinion, could limit the subject's ability to participate in the clinical investigation or to comply with follow-up requirements, or impact the scientific soundness of the clinical investigation results Any medical condition that, by the investigator judgment, will increase the risk from Hyper and Hypo-Glycemic experiment: seizures, heart disease, hypoglycemia unawareness, etc Patients who, in the opinion of the investigator, do not have sufficient manual dexterity to perform the tests themselves Patients with an inability to maintain stability of the hand during measurement or with progressive disease of the nervous system that affects movement. Patients suffering from calluses, malformations or open wounds with bandages and patients with nail polish or ceramic nails and rings. Subjects who do not understand or cannot follow the procedures involved in the use of the device under investigation