Inclusion Criteria:  Adult RA Patients who fulfilled the 2010 ACR/European league against rheumatism (EULAR) criteria for the classification of RA (7). Adult RA patients with ILD (Nonspecific idiopathic interstitial pneumonia more than 16 years old).  Exclusion Criteria:  Patients with other autoimmune diseases (systemic lupus erythematosus, polyarteritis nodosa sarcoidosis, dermatomyositis, scleroderma, spondylarthritis and inflammatory bowel disease). RA patients with lung affection other than ILD Patients with malignant tumors Patients with active infection Patients with severe heart, lung, and kidney dysfunction Patients with tuberculosis, pulmonary infection, chronic obstructive pulmonary disease, bronchiectasis, lung tumor, and pneumoconiosis disease. Uses of drugs (other than RA medication) known to cause ILD such as antimicrobial agents (Sulphonamide), cardiovascular agents (amiodarone) and Bromocriptine.