Inclusion Criteria:  Woman or man over 18 years old  Patient with symptomatic mitral leakage (grade 3+ or 4+) at high surgical risk defined as:  Age ≥ 75 years and an STS score ≥ 6%, or, according to MVARC, at least 1 fragility index or at least 1 organ fragility criterion or at least 1 operative risk criterion. MVARC recommendations are defined in the appendix. Age <75 years and an STS score> 8%, or, according to MVARC, at least 1 fragility index or at least 1 organ fragility criterion or at least 1 operative risk criterion. MVARC recommendations are defined in the appendix. Patient rejected for surgery. Patient with a life expectancy of over 1 year. Patient affiliated or beneficiary of a social security scheme. Patient having been informed and having signed a written consent.  Exclusion Criteria:  Patient with unfavorable ultrasound parameters (for example: patient with insufficient mitral surface). Patient with recent or active infection. Patient with a contraindication to the transseptal puncture. Patient with valve anatomy incompatible with the placement of the device. Patient with an anomaly of the tricuspid valve justifying a surgical intervention. Patient who has had a percutaneous cardiovascular procedure within the previous 30 days. Patient who had heart surgery in the previous 30 days. Patient with a history of surgery on the mitral valve. Patient having had a stroke in the previous 30 days. Patient participating in another clinical study. Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision. Pregnant, breastfeeding or parturient woman. Patient hospitalized without consent.