Inclusion Criteria:  Age ≥18 years; Positive polymerase chain reaction (PCR) test for SARS-CoV-2; At least one of the following symptoms: fever, cough, sneezing, dyspnea, fatigue, smell alteration, rhinorrhea, sore throat, myalgia, arthralgia, diarrhea; Outpatient COVID-19 care at the moment of enrollment (without indication for in-hospital care).  Exclusion Criteria:  Severe comorbidity with life expectancy less than 3 months; Absence of proxy for patients with communication difficulties; Absence of telephone contact; Refusal or withdrawal of agreement to participate; Previous enrollment in the study.