Inclusion Criteria:  Male and female over 18 years old. Managed at the CHUGA for a colorectal adenocarcinoma With an indication for immediate surgical resection as part of the care. Patient naive from neo-adjuvant chemotherapy Patient did not object to the CRC-ORGA-2 study  Exclusion Criteria:  Patients protected by law (pregnant or breastfeeding women, minors, patients under guardianship or trusteeship, persons deprived of their liberty or hospitalized under duress). Patients with positive HIV, HBV, HCV serology.