Inclusion Criteria:  Histologically proven gastric or gastro-esophageal junction (GEJ -Siewert type II -III) adenocarcinoma More than cT2 and/or N + (UICC 8th edition) Written informed consent  Exclusion Criteria:  Presence of ascites or distant metastases Previous chemotherapy for gastric adenocarcinoma Previous gastric surgery Absolute contraindications to surgery Concomitant malignancies or history of other malignancies in the previous 5 years (with exception of in situ cervical carcinoma, basal cell carcinoma, superficial bladder tumors are allowed if curatively treated).