Inclusion Criteria:  Confirmed pathologic diagnosis of MDS Requiring >= 2 blood transfusions in the past month if previously diagnosed or hemoglobin =< 8 g/dL if newly diagnosed Age >= 18 Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2 Ambulatory (use of a walking aid, such as a cane or rollator, is acceptable) Able to give informed consent Willing to comply with all study procedures and available for the duration of the study Able to read and/or understand English Have access to an iPhone 4S or later, iPad 3 generation or later, Android 5.0 or later, or Windows 10 device Have access to Bluetooth low energy (LE) and internet connection for syncing  Exclusion Criteria:  • Uncontrolled illness including, but not limited to, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements