Inclusion Criteria:  Japanese ancestry Diagnosed with ulcerative colitis (UC) ≥ 3 months prior to screening Having active UC confirmed by endoscopy Moderately to severely active UC  Exclusion Criteria:  Severe extensive colitis Diagnosis of Crohn's disease (CD) or indeterminate colitis or the presence, history of a fistula consistent with CD Diagnosis of microscopic colitis, ischemic colitis, or infectious colitis