Inclusion Criteria:  Confirmed high grade OC (advanced or metastatic epithelial ovarian, fallopian tube and primary peritoneal cancer):  patients with FIGO stage IIb-IV OC who are starting systemic treatment or patients with recurrent/relapsed disease, who received any previous systemic anti-tumor treatment and who are now starting systemic treatment for recurrent/relapsed disease. Locally advanced and inoperable or metastatic EC (FIGO stage III-IV) who are starting systemic first-line therapy.  Signed and dated informed consent (IC):  Patients participating in PRO module: IC before first therapy cycle Patients not participating in PRO module: IC no later than six weeks after start of first therapy cycle  Exclusion Criteria:  newly diagnosed early-stage OC (FIGO stage I-IIa) Low grade mOC OR Early-stage EC (FIGO stage I-II)