Inclusion Criteria:  Age 18 or order Ability to understand study procedures and to comply with them for the entire length of the study. Ability of individual or legal guardian/representative to understand a written informed consent document, and the willingness to sign it. Started the CT simulation procedure (about to initiate radiation therapy) or currently receiving radiation treatment for cancer at a University of California, San Francisco (UCSF) location (Mission Bay, Mount Zion, Parnassus, etc.). Reported using cigarettes, e-cigarette or any tobacco product(s) in the past 12 months  Exclusion Criteria:  Contraindication to any study-related procedure or assessment. Participated in Patient/Care Team Advisory Board Activities for the project Hearing and/or vision disabilities in receiving the iMD intervention or follow-up assessment such as videos or telephone interviews at follow-up Cancer care team's judgement of inappropriateness due to cognitive or medical reasons Inability to understand spoken and written English Completion of radiation therapy for cancer at time of enrollment