Inclusion Criteria:  The research targets patients on peritoneal dialysis with average and high transport status documented by Peritoneal Equilibrium Transport Test (PET test) in Najah National University Hospital.  Exclusion Criteria:  Patients less than 18 years An episode of Peritonitis in less than three months History of recurrent hypoglycemia ( more than two episodes during one month prior to enrollment in the study) Liver disease: Hepatic impairment aspartate transaminase [AST] or alanine transaminase [ALT] >3x the upper limit of normal [ULN]; or total bilirubin >2x ULN at time of enrolment) Any allergic reaction to dapagliflozin Type I DM Pregnancy or women who are breast-feeding Symptomatic hypotension or a mean arterial pressure (MAP) less than 60 mmHg MI, unstable angina, stroke, or transient ischemic attack (TIA) within 12 weeks before enrolment Active malignancy requiring treatment at the time of visit -