Inclusion Criteria:  Men or women aged 18 and older at the time of data registration; Presence of 2 or more of the following factors  Coronary arteries atherosclerosis (atherosclerosis revealed by means of coronary angiography and/or a history of type I myocardial infarction and/or elective PCI and/or CABG and/or angina pectoris with ischemia according to stress test results, history of CHD); Lower extremity arteries atherosclerosis (atherosclerotic plaques revealed by ultrasound, and/or ABI <0.9, and/or a history of revascularization, and/or a history of amputation associated due to chronic lower extremities arterial insufficiency); Atherosclerosis of brachiocephalic arteries or renal arteries (presence of atherosclerotic plaques according to US data and/or history of revascularization and/or history of atherothrombotic stroke or TIA in the absence of known AF); Atherosclerosis of renal arteries or abdominal aorta (presence of atherosclerotic plaques according to US data and/or history of revascularization).  Presence of one or more of the following atherosclerotic risk factors:  Anamnestic data on dyslipidemia with LDL cholesterol levels above 4.9 mmol/L or total cholesterol levels above 8.0 mmol/L; Presence of confirmed familial hypercholesterolemia; Current smoker status or history of smoking; Overweight (BMI≥ 25 kg/m2); Presence of arterial hypertension; Presence of established type 2 diabetes mellitus; Presence of an established diagnosis of prediabetes; Presence of CKD stage 3a and higher (GFR <60 ml / min / 1.73 m2).  Exclusion Criteria:  Life expectancy less than 1 year; Patient refusal to participate in the Register