Inclusion Criteria:  Age ≥18 years old With orthotopic whole-liver transplantation Liver was obtained from Brain-dead organ donors  Exclusion Criteria:  Living donor liver transplantation, split liver transplantation, partial donor liver transplantation Multivisceral or combined organ transplantation Patients with preoperative VTE Age < 18 years Died or discontinued surgery during surgery Those who died within 48 h after surgery or were discharged from hospital on their own resulting treatment discontinuity Patients with incomplete clinical data