Inclusion Criteria:  Patients of 18 years of age or older undergoing bronchoscopy for diagnosis of a peripheral lung lesion from 1 to 3.5 cm in diameter located in the outer 2/3 of the lung fields  Exclusion Criteria:  Pregnant or breastfeeding women Patients who cannot tolerate raising both arms above their head (position for obtaining mobile-CT images) Patients with any contraindication for general anesthesia (e.g., severe and active coronary artery disease, chronic obstructive pulmonary disease (COPD) with forced expiratory volume in 1 second (FEV1) < 1 liter, uncontrolled hypertension, increased intracranial pressure, history of intolerance to general anesthesia) Dementia or other severe cognitive impairment causing inability to understand or consent to the procedure and study