Inclusion Criteria Patient  Patient with a clinical suspicion for a new diagnosis of AML or MDS for whom the diagnostic molecular testing via the hematologic molecular algorithm (HMA) at BJH is requested or planned to be requested. Adult patients 18 years or older. Ability to understand and willingness to sign an IRB approved written informed consent document.  Inclusion Criteria Physician  Treating physician at Washington University School of Medicine who directs therapy for individuals with hematologic malignancies. Able and willing to complete standardized questionnaires about usability, and stakeholder perceptions of ChromoSeq during the ChromoSeq implementation process.  Exclusion Criteria Patient  Younger than 18 years of age  Exclusion Criteria Physician  Does not treat patients at Washington University School of Medicine