Inclusion Criteria:  Age >18 years Diagnosis of AML, new diagnosis or relapsed/refractory disease Planned intensive inpatient chemotherapy, defined as expected hospitalization for 4 weeks or longer Sufficient time to perform periodontal examination and treatment by the end of day 1 of chemotherapy without delaying chemotherapy Written informed consent prior to performance of any research related activities  Exclusion Criteria:  Unstable for transfer to the School of Dentistry Fever at the time of enrollment Documented blood stream infection at the time of enrollment Inherited bleeding diathesis Periodontitis requiring treatment before starting chemotherapy ANC <0.5 x 10^9/L at the time of enrollment Unstable for transfer to the School of Dentistry Fever at the time of enrollment Documented blood stream infection at the time of enrollment Inherited bleeding diathesis Periodontitis requiring treatment before starting chemotherapy