A Single Center Randomized Prospective Study on the Peristaltic Direction of Gastrointestinal Anastomosis in Roux-en-Y Reconstruction After Distal Curative Gastrectomy for Gastric Cancer
Phase: NA
Conditions: Peristaltic Direction, Roux-en-Y Gastrointestinal Anastomosis, Gastric Cancer
Sponsor: Tianjin Medical University Cancer Institute and Hospital

 
 
 
 
A single center randomized prospective study on the peristaltic 
direction of gastrointestinal anastomosis in Roux-en-Y reconstruction 
after distal curative gastrectomy for gastric cancer 
（DJY002 Trail） 
 
 
 
 
Edition Number： 1.0 
Edition Generation Date： Qct 30, 2020 
Principal Investigator： Jingyu Deng and Han Liang 
Research Institute： Cancer Hospital & Institute of Tianjin Medical University 
 
 

Protocol: 
 
Randomized included in the study 
Isoperistaltic direction of gastrointestinal 
anastomosis in Roux-en-Y reconstruction 
Group A（Isoperistaltic anastomosis）
（n=74） 
Group B（Antiperistaltic anastomosis）
（n=74） 
Undergo curative gastrectomy plus lymphadenectomy 
Antiperistaltic direction of gastrointestinal 
anastomosis in Roux-en-Y reconstruction 
– 
Distal gastric adenocarcinoma (antrum, pylorus, angle, and/or lower part of body) identified by 
histopathologic examination without non-curative resection factors 
– 
Undergo potentially curative gastrectomy plus lymphadenectomy (cTanyNanyM0) 
– 
Age between 18 and 70 years 
– 
KPS score >60 
– 
No neoadjuvant therapy 
– 
No seriously chronic diseases of important organs 
Differences of effects of early recovery 
postoperatively (exhaust, defecation, eating, 
residual stomach peristalsis, length of hospital 
stay, etc.) 
Differences of later gastrointestinal effects 
(bile reflux, residual gastritis, gastric emptying 
function, etc.) 
Evaluation the a reliable peristaltic direction method of gastrointestinal anastomosis 
in Roux-en-Y reconstruction for patients in favor of making an important 
contribution to reduce medical costs and potential improvements of the prognosis 
after distal curative gastrectomy for gastric cancer.