MsFLASH: Living a Healthy Menopause, Aim 2 Randomized Controlled Trial of MyMenoPlan
Phase: NA
Conditions: Menopause, Premenopause, Postmenopause
Sponsor: University of California, San Diego

UNIVERSITY OF CALIFORNIA, SAN DIEGO 
 
UCSD 
 
 
BERKELEY   DAVIS   IRVINE   LOS ANGELES   MERCED   RIVERSIDE   SAN DIEGO   
 
 
 
SAN FRANCISCO   SANTA BARBARA   SANTA CRUZ 
 
 
HERBERT WERTHEIM SCHOOL OF PUBLIC HEALTH and HUMAN LONGEVITY SCIENCE 
 
 
 
9500 GILMAN DRIVE, MC 0725 
LA JOLLA, CALIFORNIA 92093-0725 
 
 
 
MyMenoPlan: Online Resource for Improving Women's Menopause Knowledge and 
Informed Decision-making 
 
Principal Investigator: Andrea LaCroix, PhD 
UC San Diego 
Herbert Wertheim School of Public Health and Human Longevity Science 
Email: alacroix@ucsd.edu 
 
NCT: 05299983 
Study Protocol: 3/31/2023 
 

MyMenoPlan: Online Resource for Improving Women’s 
Menopause Knowledge and Informed Decision-making 
 
Study Protocol 
 
Study Participants 
Participants will meet the following eligibility criteria: 
• Age 40 – 60 years 
• Reside in the U.S. 
• Have questions about their own perimenopause/menopause or at least one 
symptom 
• Have interest in looking at a website about menopause for themselves 
• Willingness to spend at least 20 minutes on a website and answer a 15-minute 
questionnaire 
• Able to read and write in English 
 
Recruitment & Informed Consent 
The study has approval by the Institutional Review Board at the University of California, 
San Diego Human Research Protections Program Office, (140604) and registered at 
the Clinical Trial Registry www.clinicaltrials (NCT05299983). 
 
Participants will be recruited nationally using IRB approved advertisements on 
Facebook & Instagram. Once a participant clicks on a Facebook or Instagram ad, an 
online form in Qualtrics will open.  Participants will read the information sheet (consent) 
and provide online consent.  Participants will need to provide an email address.  Once a 
participant provides consent, they will immediately receive an email with the study link. 
After opening the survey, the participants will complete a demographics survey and then 
will be randomized to one of two study groups (See Study Design below).   
 
Study Design 
Participants will be randomized to one of two study groups and be asked to leave the 
survey open, spend at least 20 minutes on the website(s), and then return to complete 
the survey: 
 
• MyMenoPlan (Intervention group) 
o Participants will review the MyMenoPlan.org website 
• Control 
o Participants will be able to view any website of their choice including three 
high quality websites linked in the survey that were run by scientific, non-
commercial, or governmental orgs. 
 https://www.menopause.org/for-women 
 https://www.womenshealth.gov/menopause 
 https://www.nia.nih.gov/health/topics/menopause  
 
Compensation – Participants will receive $30 if they passed all fraud detection (see 
below) and completed all the study tasks. 
 

Fraud detection and noncompliance 
One difficulty with studies that are conducted entirely only online is that there is an 
opportunity for bots, bad actors, and others who are not eligible to attempt to complete 
the study for the incentive money.  We will employ the following fraud detection and 
noncompliance quality checks: 
 
• Include the requirements for payment listed on information sheet, so that we can 
eliminate and not pay people who did not meet the inclusion criteria.  
• The survey software will use reCAPTCHA to detect and eliminate bots.  
• Eliminate participants who: 
o spend less than 30 minutes combined on the site and questionnaire,  
o put in straight-lined responses to significant portions of the survey (giving 
the same answer across a large sequence of questions, despite reverse 
coded items)  
o fail attention checks (not giving the requested answer to an item on the 
survey like “Select answer B for this question”).  
 
• Not allow more than one survey completion from the same IP or email address.  
o We will manually check the consistency of names, addresses, phones, 
and email addresses at Spokeo.com, an online people look-up service.  
 
Measures 
Primary Outcome Measures: 
• Perceived Quality of Information  
o This 7-item, 5-point Likert scale (1- Strongly disagree to 5 - Strongly 
agree) is adapted from the Post-Study System Usability Questionnaire 
(PSSUQ) in Lewis (1995). 
 
• Readability 
o This 2-item, 5-point Likert (1- Strongly disagree to 5 - Strongly agree)scale 
was derived from the Standardized User Experience Percentile Rank 
Questionnaire (SUPR-Q) in Sauro (1995). 
 
• Self-Efficacy for Managing Menopause Symptoms 
o This is a newly developed Likert scale (1- Strongly disagree to 5 - Strongly 
agree) for assessing participants' beliefs in their own abilities in managing 
menopausal symptoms. 
 
• Credibility 
o This 2-item, 5-point Likert (1- Strongly disagree to 5 - Strongly agree) 
scale was derived from the Standardized User Experience Percentile 
Rank Questionnaire (SUPR-Q) in Sauro (1995).