Evaluation of Healthcare Workers Knowledge Regarding Their Vaccination Status and Their Relationship to Vaccination at Melun Hospital
Conditions: Vaccinia
Sponsor: Groupe Hospitalier Sud Ile-de-France

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SUMMARY OF THE PROTOCOL FOR RESEARCH MENTIONED IN 3O OF 
ARTICLE L. 1121-1 OF THE PUBLIC HEALTH CODE INVOLVING ONLY 
QUESTIONNAIRES OR INTERVIEWS 
 
Research title 
Evaluation of healthcare workers knowledge 
regarding their vaccination status and their 
relationship to vaccination at Melun Hospital 
Acronym 
Statuvax Pro 
 
Registration number (ID-RCB) 
2023-A00923-42 
Date and version number of abstract : 
Version 6 of 31/07/2023 
Date and version number of information and consent 
form : 
 
Version 4 of 31/07/2023 
Date and version number of questionnaires  / Interview: 
 
Version 4 of 31/07/2023 
Compliance of this request with the procedure planned in II of article R. 1123-20 of the French Public Health Code (a 
negative response to one of the four criteria below means that you are not qualify for this procedure) : 
This research involves only data collected by questionnaire(s) or interview(s) : 
☒       YES 
☐   NO 
This research hasn’t consequences for the participants, either in terms of safety or in terms of modifying their 
usual care 
☒       YES 
☐   NO 
This research is risk-free and the disadvantages for the research participants are negligible: 
☒       YES 
☐   NO 
The collection and processing of data used in this research complies with the reference methodology MR003 approved 
by the CNIL : 
              ☒       YES 
              ☐   NO 
Administrative informations 

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Last name, first name (individual sponsor) or legal form, 
name (corporate promoter) : 
Groupe Hospitalier Sud Ile de France  
E-mail address : 
drc.promotion@ghsif.fr   
Adress : 
270 avenue Marc Jacquet 77000 Melun 
Telephone : 
01 81 74 17 17 
Head of Clinical Research Unit 
M. Arezki AGHER 
E-mail 
arezki.agher@ghsif.fr  
Phone/Fax 
Tel : 01 81 74 22 28 
Fax : 01 81 74 25 59 
Investigator or, if applicable, coordinating investigator  
Last name, First name and Function : 
Dr Pierre Leroy, MD 
E-mail address : 
pierre.leroy@ghsif.fr 
Address of main research location : 
270 avenue Marc Jacquet 77000 Melun 
Phone : 
01 81 74 20 62 
Nombre de centre si recherche multicentrique : 
Monocentric research 
Background and rationale 
Research background 
Vaccination coverage for adults in France is mediocre: only 
44% of people aged 65 and over are up to date with 
diphtheria, tetanus and infectious polio vaccinations (1), 
and in an earlier study in 2002, among people aged 16 and 
over, 71.2% against tetanus, 41.9% against infectious polio 
and 33.7% against diphtheria (2). Other vaccinations, such 
as pneumococcal, may be recommended depending on the 
individual's co-morbidities, and vaccination coverage is 
sometimes very low, depending on the pathology (less 
than 2% of people living with diabetes mellitus are 
correctly immunized against pneumococcus) (3), whereas 
vaccination coverage against SARS-CoV-2 is much better 
(over 90% among diabetics, for example), according to 
French health insurance data (4), under the influence of a 
proactive, even coercive vaccination policy. 
 
Healthcare professionals in France are subject to a number 
of vaccination obligations, and following successive anti-
SARS-CoV2 vaccination campaigns, these obligations are 
under discussion. Even healthcare professionals are 
reluctant to be vaccinated (5-7), particularly in view of 

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annual vaccination rates against seasonal influenza: 22% 
were vaccinated against seasonal influenza in 2022, and 
25.9% knew their general vaccination status (8). 
 
As part of the national "European Vaccination Week" event 
organized by the French Ministry of Health and Prevention, 
we propose a questionnaire designed for hospital 
healthcare workers to assess their knowledge of their own 
vaccination status, and evaluate their attitude with 
vaccination. 
 
1. 
National Institute of healh monitoring (InVS). 
National survey  of vaccine coverage, France, January 
2011. Vaccination coverage against seasonal influenza in 
target groups and measure of vaccine efficacy. Vaccination 
coverage with diphtheria-tetanus-polio vaccines (dTP) 
and... [Internet]. 2011 [cited 11 Apr 2023] p. 21. Available 
from : 
https://www.santepubliquefrance.fr/content/download/1
81715/2304769?version=1 
2. 
Guthmann JP, Fonteneau L, Antona D, Lévy-Bruhl D. 
Vaccination 
coverage 
against 
diphtérie, 
tétanos, 
poliomyélite among adults in France : results of the health 
and social protection survey, 2002. Bull Epidemiol Hebd. 
déc 2007;(51‑52):441‑5.  
3. 
Wyplosz B, Fernandes J, Sultan A, Roche N, Roubille 
F, Loubet P, et al. Pneumococcal and influenza vaccination 
coverage among at-risk adults: A 5-year French national 
observational study. Vaccine. 5 août 2022; 40(33):4911‑21.  
4. 
Data Vaccin Covid (Assurance Maladie) [Internet]. 
[cité 11 avr 2023]. Disponible sur: https://datavaccin-
covid.ameli.fr/pages/home/ 
5. 
Haviari S, Bénet T, Saadatian-Elahi M, André P, 
Loulergue P, Vanhems P. Vaccination of healthcare 
workers: A review. Human Vaccines & 
Immunotherapeutics. 2 nov 2015;11(11):2522‑37.  
6. 
Paterson P, Meurice F, Stanberry LR, Glismann S, 
Rosenthal SL, Larson HJ. Vaccine hesitancy and healthcare 
providers. Vaccine. 20 déc 2016;34(52):6700‑6.  
7. 
Napolitano F, Bianco A, D’Alessandro A, 
Papadopoli R, Angelillo IF. Healthcare workers’ knowledge, 
beliefs, and coverage regarding vaccinations in critical care 
units in Italy. Vaccine. 31 oct 2019;37(46):6900‑6.  
8. 
Santé Publique France. Quelle est la couverture 
vaccinale contre la grippe des professionnels exerçant 
dans les établissements de  santé ? [Internet]. Santé 

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Publique France; 2022 juin p. 6. (Le point sur.). Disponible 
sur: https://www.santepubliquefrance.fr/maladies-et-
traumatismes/maladies-et-infections-
respiratoires/grippe/documents/enquetes-etudes/quelle-
est-la-couverture-vaccinale-contre-la-grippe-des-
professionnels-exercant-dans-les-etablissements-de-
sante-point-au-1er-juin-2022 
Research hypotheses 
Knowledge of own vaccination status is less than 
50% among healthcare workers working at Groupe 
Hospitalier Sud Ile de France. 
 
 
Objectives and evaluation criteria 
Primary research objective and primary endpoint 
(maximum 750 characters) 
Evaluation of the rate of knowledge of own 
vaccination status among healthcare workers 
working at Groupe Hospitalier Sud Ile de France. 
Secondary objective(s) and potential secondary 
endpoint(s) (maximum 1500 characters) 
Assessment 
of 
the 
relationship 
between 
healthcare workers of Groupe Hospitalier Sud Ile 
de France and vaccination in general. 
Study Organization 
A. Summary description of the study plan (maximum 
750 characters) 
Questionnaire : Hetero-randomized, anonymous, 
online questionnaire proposed as a 
recommendation during the "European 
Vaccination Week" event. 
 
Link to questionnaire :  
https://redcap.ghsif.fr/surveys/?s=JEWWTMCMF
EDNN9FD 
 
B. Questionnaire/interview methodology 
 
- Questionnaire (s) Yes 

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Terms and conditions : 
 
Questionnaire administered by:  
☐  E-mail 
☒   internet 
☐   phone 
☐   face to face 
☐   other (specify) 
 
Questionnaire administered in : 
☒   one go 
☐   several times (specify number of times) 
Questionnaire type: 
☒  if validated, indicate origin of validation: The questionnaire was tested on a sample of the target population 
and experts. 
☐  if not validated, justify : 
Free comments (if necessary, to clarify the above answers, especially when more than one questionnaire is passed) : 
Free comments (if necessary, to clarify the above answers, especially when several interviews are held) : 
C. Statistical analysis framework and/or biostatistician's 
references : 
Descriptive statistics (frequencies, means, standard 
deviations). Analysis of independent variables using the 
Chi-2 test. 
Information on research implementation 
A. Type of research location (e.g. hospital 
department, doctor's surgery, school, etc.) 
Hospital department 
B. Estimated duration of research : 
1 week 
C. Estimated duration of participation per person : 
10 minutes 
D. Does the research also involve retrospective data 
collection : 
☐  YES 
☒  NO 

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E. Personnes incluses dans la recherche  
Number of participants : 
At least 100  
Inclusion criteria : 
Anyone working at GHSIF 
Non-inclusion criteria : 
Any person refusing to participate 
Secondary exclusion criteria : 
Demonstration of the right to withdraw from the study 
Does the research include people with no affection? 
Yes 
Method of recruiting survey participants : 
Healthcare executives, department heads 
Information and traceability procedures for non-
opposition : 
Signed non-opposition form 
F. Disadvantages for research participants 
Estimated duration of data collection by interview or 
questionnaire for one participant : 
10 min 
Anticipated total duration of research participation for a 
participant if data collection is carried out in several stages 
(duration between inclusion and last data collection) : 
10 min 
Maximum transport time estimated for participants if 
applicable : 
N/A