Effects of Emotion-focused vs. Cognitive Schema Therapy Interventions on Emotion Regulation Deficits in Borderline Personality Disorder - Associations Between Clinical Efficacy, Brain Network Function and Local Glutamate/GABA Metabolism
Phase: NA
Conditions: Personality Disorders
Sponsor: Jena University Hospital

Borderline Personality Disorder and Emotion Regulation
Effects of emotion-focused vs. cognitive schema therapy interventions on emotion regulation deficits in 
borderline personality disorder - associations between clinical efficacy, brain network function and local 
glutamate/GABA metabolism
Ethiks approval 04.06.2018, last time edited

T0                     
Inclusion          
Therapy beginning
T1                     
End of therapy
T3                             follow-
up 1
T4                
follow-up 2
Week 1*
Week 9**
6 month after therapy
1 year after 
therapy
Diagnostic phase
Outcome (1)
Outcome (2)
Outcome (3)
PF-TK (s)
X
X
SEFP (c)
X
X
X
X
PID-5 (s)
X
X
X
X
BPDSI-IV (c)
X
X
X
X
EHI (s)
X
CTQ (s)
X
IDA-R
(X)
WAIS-IV
(X)
ERI (s)
X
X
X
X
FSVV (s)
X
X
X
X
BSL-95 (s)
X
X
X
X
IIP (s)
X
X
X
X
SMI (s)
X
X
X
X
YSQ-S3r (s)
X
X
X
X
BDI II (s)
X
X
X
X
SCL-90-R (s) 
X
X
X
X
*questionnaire 
survey in week 1
**questionnaire 
survey in week 9
Reference:
PF-TK (s)
SEFP (c)
Bender et al. (2011)
PID-5 (s)
Krueger (2012), Zimmermann et al. (2014)
BPDSI-IV (c)
Arntz et al. (2003), Kröger et al. (2013, 2016)
EHI
Oldfield (1971)
CTQ (s)
Bernstein et al. (2003); Klinitzke et al (2012) 
IDA-R
Retz et al.  (2012)
WAIS-IV
Wechsler (2008)
ERI (s)
König et al. (2011)
FSVV (s)
Reicherzer & Brandl (2011)
BSL-95 (s)
Bohus et al. (2001, 2007)
IIP-D (s)
Horowitz et al. (1988, 2000)
SMI (s)
Lobbestael et al (2010), Reiss et al. (2012), Young et al. (2007)
YSQ-s3r (s)
Kriston et al. (2013), Phillips et al. (2017), Young et al. (1994)
BDI-II (s)
Beck et al. (1996), Hautzinger et al. (2006), Kühner et al. (2007)
SCL-90-R (s) 
Derogatis (1979), Franke (2002), Schauenbuerg & Strack (1999)
(c) clinician-administered                              
(s) self-rated                                                       
(x) if applicable
Borderline Personality Disorder Severity Index – fourth version
Edinburgh Handedness Inventory
Childhood Trauma Questionnaire
structured guide for the integrated diagnosis of adult ADHD
Patient Questionnaire Day-Clinic Jena
Levels of Personality Functioning Scale (LPFS)
Personality Inventory for DSM-5 (Criterion B)
Borderline Symptom List (95 Items)
Inventory of Interpersonal Problems 
Wechsler Adult Intelligence Scale - fourth version
Emotion Regulation Inventory
Questionnaire concerning self-harming behavior (modified)
Schema Mode Inventory (118 item version)
Young Schema Questionnaire (short version)
Beck Depression Inventory-II 
Symptom Checklist-90-Revised 
• Primary outcome
• Secondary outcome (BPD-specific)
• To control for occurence and change of  
depressive  and other psychiatric symptoms
• Diagnostics
• Inclusion/exclusion criteria
Assessments