The Effect of Preoperative Ketamine on the Emergence Characteristics After Desflurane or Sevoflurane Anesthesia in Children Undergoing Entropion Surgery
Phase: NA
Conditions: Entropion
Sponsor: Inje University

ID: 2016-01      
The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing 
Entropion Surgery      
NCT02916407 
04-25-2019 
We compared the emergence characteristics of sevoflurane versus desflurane with ketamine 
premedicated pediatric patients for ambulatory surgery. The primary outcome was compared the 
extubation time between sevoflurane versus desflurane anesthesia. The secondary outcome was 
compared the emergence characteristics (emergence agitation) between two groups. 
Patients were randomly assigned into group S (sevoflurane) or group D (desflurane). After 
intravenous access in day-surgery unit, ketamine 1mg/kg was administered for separation from their 
parents, and then they were transferred to operating room with monitoring pulse oximetry. General 
anesthesia was maintained with sevoflurane in group S or desflurane in group D.  
Data were analyzed using Medcalc 14.12.0 (MedCalc Software bvba, Ostend, Belgium). 
Parametric variables were described as mean ± standard deviation (SD). Qualitative variables 
were described as number and as median (interquartile range). Student’s t-test, Fisher’s exact 
test, or Mann-Whitney U-test was used as appropriate to compare the two groups. P < 0.05 was 
considered to indicate statistical significant. 
  
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