Anesthesia of Endolaryngeal Surgery With a Special Endotracheal Laser Tube
Conditions: Anesthesia, Anesthesia Morbidity
Sponsor: University of Pecs

Titel of study: Anesthesia With Endotracheal Laser Tube 
Clnical Trials.gov ID: NCT03044418 
Protocol ID: 6419 
 
Protocol  
Preparation of endtracheal tube before anesthesia: The endotracheal tube is made of 
polyvinylchloride (PVC). PVC tube wrapped material is an aluminum tape with adhesive 
back. Wrapping starts from junction of tube and proximal end of cuff with compliance of 
sterility rules. Wrapping in spiral is with scalpel to 60 degrees and 50% overlap layer. The 
intubation is done with this special endotracheal tube and its cuff was inflated with saline and 
methylene blue mixture. 
Anesthesia: Midazolam 7.5 mg is administerd orally 1.5 h before induction of anesthesia. 
Ringer lactate is used as background infusion at the rate of 5 mL/kg/h during anesthesia. 
Electrocardiography (ECG), non-invasive blood pressure (NIBP), heart rate, peripheral 
capillary oxygen saturation (SpO2), and end-tidal carbon dioxide are continuously monitored 
intraoperatively. Anesthesia is induced with fentanyl, propofol and atracurium. After five 
minutes of preoxygenisation with 100% oxygen, an initial dose of fentanyl 1 μg/kg is 
administered intravenously (IV). An intubation dose of 0.5 mg/kg IV atracurium is 
administered to all patients. The repeat dose of atracurium 0.15 mg/kg is given every 30 
minutes during anesthesia Anesthesia is maintained with propofol and fentanyl. Fresh gas 
flow (FGF) is 2 L/min with the <30% FiO2 during anesthesia. Before extubation an atropine-
neostigmine mixture (1.0 and 2.5 mg) is administered as neuromuscular block reversal to all 
patients. Diclofenac and nalbuphine are administered as rescue analgesics. 
Safety and protection: Eye of the patient should be taped closed and covered with opaque 
saline swabs. Eye protection for the working personals (surgeon, anesthesiologist and 
assistants) is necessary and important too, e.g. safety goggles and specific lens in the 
microscope. Working personals must use a special efficient smoke mask. Surgical drapes 
made of flame resistant or waterproof material. 
 
Our hypothesis is that this special PVC tube with aluminum tape is safety during anesthesia of 
endolaryngeal laser surgery. Primary outcome is the number of side effects of anesthesia with 
a special laser tube.  
 
06-12-2016.