Pain Modulatory Profiles in Stretching in Healthy Participants
Phase: NA
Conditions: Healthy
Sponsor: University of Central Florida

Pain Modulatory Profiles in Stretching 
NCT05891353 
8/26/2024 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

STUDY PROTOCOL 
This study was a crossover trial of healthy participants.  After providing written informed consent, 
participants were screened for eligibility criteria.  Eligible participants then underwent three interventions 
across three separate sessions.  First, participants completed a cold water immersion task that included 
immersion of the dominant hand in a bath of water for 1 minute, 4 times.  Second, participants completed 
a pain inducing stretching in which they underwent stretching of the upper trapezius for a moderate 
intensity for 1 minute, 4 times.  Third, participants underwent a pain free stretch in which they underwent 
stretching of the upper trapezius for a low intensity for 1 minute, 4 times.  Between each minute, pressure 
pain threshold was assessed at the non-dominant webspace of the foot. 
STATISTICAL ANALYSIS 
To examine the immediate changes in PPT by condition, a repeated measures ANOVA was conducted.  
Simple effects decomposition with Bonferroni correction were completed.  Our a priori alpha level is 
<0.05.