Non-compliance on Treatment Among Diabetic Students at Sohag University
Conditions: Diabetes Mellitus, Type 1
Sponsor: Sohag University

 
Non-compliance on treatment among 
diabetic students at Sohag University  
 
 
 
 
 
NCT05286450 
 
14/3/2022 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Introduction: 
         Diabetes mellitus (DM) is a metabolic disorder resulting from a defect in 
insulin secretion, insulin action, or both, and its prevalence is rapidly rising all 
over the globe at an alarming rate [1]. 
        Diabetes mellitus is a common and costly chronic medical illness . Individuals 
with diabetes are at greater risk of long-term complications such as kidney disease, 
peripheral vascular disease, lower extremity ulcers and amputations, retinopathy, and 
neuropathy. Diabetes is considered one of the most psychologically and behaviorally 
demanding of the chronic medical illnesses , and 95% of diabetes management is 
conducted by the patient [2] . 
         Diabetes is a chronic disorder and the process of care of patients with 
diabetes is complex. It requires frequent self-monitoring of blood glucose, 
exercise, dietary modifications and administration of medications and/ or insulin.                      
Medication adherence refers to the extent to which patients take their medication  
regimen as prescribed by their health care provider[3].  
           Adherence to treatment in diabetic patients is one of the key factors in the 
process of treatment and recovery of these people[4].  
              Non-adherence to prescribed treatment schedule continues to be a major 
problem the world over especially for medications in chronic diseases The 
diabetes control and complication trial (DCCT) and other intervention 
studies demonstrated that achieving optimal glucose control through adherence to 
medications, exercise and diet prevents or minimize serious long term 
complications[5]. 
           Insulin therapy is essential for patients with Type 1 diabetes mellitus if they are 
to achieve good glycaemic control . Indeed, guidelines issued by the American 
Diabetes Association and the National Institute for Health and Clinical Excellence 
(NICE) state that insulin is the most effective glucose-lowering agent and that insulin 
therapy is a key component of effective diabetes management over the course of the 
disease . Despite the strong evidence that achieving good glycaemic control helps 
prevent the development and progression of long-term micro- and macrovascular 
complications of diabetes, many patients do not achieve such control[6]. 
 

Aim of the study: 
         Studying  noncompliance among diabetic students in Sohag University. 
 
Objectives of the study: 
1-To determine factors affecting non compliance on treatment among diabetic 
students.  
2-To detect relation between non compliance on treatment and development of 
complications.  
 
Methodology: 
Study population and localities: 
Total coverage of diabetic students aged between 18 and 25 years old in different 
faculties in Sohag University. 
Strategy: 
A cross-sectional study on diabetic students in Sohag University will be conducted to 
collect data about factors affecting  compliance and adherence to diabetes 
treatment and its impact on development of complications. 
1-Technical design: 
 Personal interviews with diabetic students through a standardized questionnaire 
(Diabetes Self Management Questionnaire (DSMQ))[7]. 
2-Administrative design: 
Personal communications with local health authorities and informed consent will be 
obtained from all the participants. 
Personnel : 
The fieldwork of this study will be carried out by the researcher under continuous 
supervision of the supervisors. 
3-Operational design: 
a) Preparatory phase : include : 
-Review of literature  
-Construction of questionnaire  
-Personal communications  
b) Second phase (data collection): 
-Nature and aim of study will be explained to the participants.  

-Data collection by the researcher through the questionnaire.  
c)Third phase (analysis of data):  
Use of SPSS program for data entry and analysis. 
Constraints and limitations of the field work: 
1- Contact with general administration of medical affairs. 
2- Collecting data about the diabetic students and their contact information. 
Time schedule of the study: 
Phases of the study:  
Time consumed  
Preparatory phase  
Second phase  
Third phase  
 
1 month 
3 months 
3 months  
 
 
Plan of study: 
 
 
 
 
Preparation of questionnaire
Communication with general 
adminstartion of medical 
affairs to get students data 
Interviewing the students 
Analysis of the data using 
SPSSprogram

 
Ethical consideration: 
 Ethical consideration will be observed in each step of the study conducted  
 Approval of Ethical Committee of Sohag faculty of Medicine will be 
secured. 
 In addition, the objectives and steps of the study will be explained to the 
participants before taking any information. 
 Informed consent will be taken from all the students participating in the 
study. 
References: 
 
١ .  
Kassahun, A., E.M. Fanta Gashe, and W.A. Rike, Nonadherence and factors affecting 
adherence of diabetic patients to anti‐diabetic medication in Assela General 
Hospital, Oromia Region, Ethiopia. Journal of pharmacy & bioallied sciences, 2016. 
8(2): p. 1٤٢ .
 
٢ .  
Ciechanowski, P.S., et al., The patient‐provider relationship: attachment theory and 
adherence to treatment in diabetes. American Journal of Psychiatry, 2001. 158(1): p. 
29-35 . 
٣ .  
Horii, T., et al., Determina"on of factors aﬀec"ng medica"on adherence in type 2 
diabetes mellitus patients using a nationwide claim‐based database in Japan. PloS 
one, 2019. 14(10): p. e0223431 . 
٤ .  
Kongkaew, C., et al., Depression and adherence to treatment in diabetic children and 
adolescents: a systematic review and meta‐analysis of observational studies. 
European journal of pediatrics, 2014. 173(2): p. 203-212 . 
٥ .  
Riaz, M., et al., Factors associated with non‐adherence to insulin in patients with type 
1 diabetes. Pakistan journal of medical sciences, 2014. 30(2): p
 .٣٣٢ .
 
٦ .  
Davies, M., et al., Real‐world factors affecting adherence to insulin therapy in 
pa"ents with Type 1 or Type 2 diabetes mellitus: a systema"c review. Diabetic 
Medicine, 2013. 30(5): p. 512-524 . 
٧ .  
Schmitt, A., et al., The Diabetes Self‐Management Questionnaire (DSMQ): 
development and evaluation of an instrument to assess diabetes self‐care activities 
associated with glycaemic control. Health and quality of life outcomes, 2013. 11(1): 
p. 1-14 .