Risk Factors for Nausea and Vomiting After Cesarean: Observational Prospective Study
Conditions: Postoperative Nausea and Vomiting
Sponsor: Brasilia University Hospital

Cover page 
May 1, 2016 
NCT number NCT03171688 
Official Title: Risk Factors for Nausea and Vomiting After Cesarean 
Internal study ID: NVPOCesarianasGabriel2017 
 

Study protocol 
1. Eligible patients will be invited to participate when cesarean section is indicated 
and the anesthesiologist asked to provide anesthesia. 
2. We will begin the informed consent protocol. 
3. Specific data will be collected before operating room: identification, age, previous 
PONV status (no previous surgery, previous surgery and no PONV, previous surgery 
and ponv), history of motion sickness, gestational age, smoking status, nausea in the 
first trimester, nausea in the third trimester. 
4. More data will be collected in the operating room: initial mean arterial pressure 
(measured by the anesthesiologist), anesthesia technique, heavy bupivacaine spinal 
dose, Sufentanil spinal dose, fentanil spinal dose, morphine spinal dose, if received 
intravenous opioids, intraoperative nausea, intraoperative vomiting, lowest mean 
arterial pressure after anesthesia, if vasopressors were used and how (if prophylactic 
or after symptoms); 
5. Some secondary outcome data will be collected in post anesthesia care unit (PACU) 
during the first 2 hours: nausea and intensity (0-10), vomiting episodes number. 
6.The main outcome data will be collected 24 hours after the cesarean, for 
complications between 2-24 hours after the cesarean: nausea and intensity (0-10), 
vomiting episodes number. 
7. Informed consent will be confirmed in the end by repeating explanations to the 
patient and asking her for signing the informed consent form. 
 
Data will be collected electronically and a comma separated values file (CSV 
extension) will be  generated for analysis. The file will be named NCT03171688.CSV