Evaluation of the Effect of a Cosmetic Product for Teeth Care in Maintaining the Whitening Effect of a Professional Dental Cleaning Performed by a Dentist - In Use Test Under Dentist Control Study
Phase: NA
Conditions: Tooth Color
Sponsor: Lacer S.A.

 
 
 
Evaluation of the effect of a cosmetic product for teeth care in maintaining the 
whitening effect of a professional dental cleaning performed by a dentist – In 
use test under dentist control study  
 
Protocol ID: PIT0000327/25 
Date: 30Jan2026 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Study synopsis 
 
The study is aimed to assess the eﬃcacy of a cosmetic product (toothpaste) in 
maintaining the whitening effect of a professional dental cleaning performed by 
a dentist in comparison to regular toothpaste.  
In order to reach this goal, a double-blind, randomized, parallel-group, placebo-
controlled clinical study is planned to be performed on 50 (56 enrolled) healthy 
female and male subjects more than 18 years old, with tooth stains enrolled 
according to the speciﬁc inclusion and non-inclusion criteria. The subjects will 
have a professional dental cleaning done at the beginning of the study and use 
the assigned product (experimental or regular toothpaste according to the 
randomization list) for 28 days following the procedure. Speciﬁc assessments 
will be carried out before and after 5, 14 and 28 days of product use. The 
occurrence of adverse events will be also recorded. The study was approved by 
an independent ethics committee, and no protocol amendments were done after 
the approval.