In Vivo Study for the Evaluation of the Efficacy of an Adjunct Mouthwash in Hygiene, Wound Healing, Analgesia, and Functional Recovery Following Trauma or Dental Procedures in Gingival Tissue
Phase: NA
Conditions: Damaged Oral Mucosa
Sponsor: Lacer S.A.

 
 
 
In vivo study for the evaluation of the eﬃcacy of an adjunct mouthwash in 
hygiene, wound healing, analgesia, and functional recovery following trauma or 
dental procedures in gingival tissue. 
 
 
Protocol ID: 23-003-01 
Date: 14Dec2023 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

 
Study synopsis 
 
The study was aimed to assess the eﬃcacy of a cosmetic product in improving 
oral mucosa healing after dental intervention. In order to reach this goal a 
randomized, placebo controlled, blind, single centre study was carried out on 94 
(100 enrolled) healthy female and male subjects more than 18 years old, enrolled 
according to the speciﬁc inclusion and non-inclusion criteria. The subjects had a 
dental procedure on oral mucosa tissue and used the mouthwash or placebo 
(according to the randomization list) for 15 days following the procedure. Eﬃcacy 
evaluations were performed at baseline (T0), after 7 (T7) and 15 days (T15) of 
product use by means of the post procedure would aspect assessment grading 
on Likert scale, as well as the pain evaluation on the 0 to 10 scale.  The study was 
approved by an independent ethics committee, and no protocol amendments 
were done after the approval.