A Prospective Clinical Study to Validate a Preoperative Risk Scoring Model for Lymph Node Metastasis in Gastric Cancer Patients
Conditions: Predictive Cancer Model, Gastric Cancer, Lymph Node Metastasis
Sponsor: Tianjin Medical University Cancer Institute and Hospital

 
 
 
 
A clinical prospective study to validate a risk scoring model integrated 
preoperative immune-inflammatory indicators, tumor markers and 
imaging examination for the lymph node metastasis of gastric cancer 
before surgery（DJY004 Trail） 
 
 
 
 
Edition Number： 1.0 
Edition Generation Date： Jul 01, 2023 
Principal Investigator： Jingyu Deng  
Research Institute： Cancer Hospital & Institute of Tianjin Medical University 
 
 

Protocol: 
 
 
– 
Curative gastrectomy and D2 lymphadenectomy 
– 
Postoperative pathology confirmed gastric cancer without distant metastasis or peritoneal 
dissemination (M0) 
– 
Age between 18 and 70 years 
– 
KPS score >60 
– 
No autoimmune, inflammatory, or blood diseases, no active infection  
– 
No seriously chronic diseases of important organs 
– 
No other malignancies 
Calculation of lymph node metastasis risk of patients based on the previously 
constructed prediction model. 
Collection of preoperative clinical data of patients including: CT examination 
results (regional lymph nodes with a maximum short diameter ≥10mm 
considered positive), PLR, CEA, CA242, CA724 levels. 
To analyze the consistency between the actual results of postoperative lymph node 
metastasis occurrence and the predicted results by the risk scoring model to 
identify the clinical applicability of the model. 
Collection of postoperative pathological data and lymph node status of patients. 
Patients included in the study 
N≥100