Effect of Bariatric Surgery on Cognitive Performance Assessed Using a Virtual Reality Program and the Neuropsi Battery.
Phase: NA
Conditions: Obesity (Disorder), Obesity and Obesity-related Medical Conditions
Sponsor: Hospital General de México Dr. Eduardo Liceaga

 
 
 
Evaluation of Cognitive Improvement After Bariatric Surgery Using a Virtual Reality Program and the 
Neuropsi Neuropsychological Battery 
 
 
Unique Protocol ID: DI/24/501/04/37 
 
 
NCT number: NCT ID not yet assigned 
 
 
Date: 11/13/2025
 

Title: “EFFECT OF BARIATRIC SURGERY ON COGNITIVE PERFORMANCE EVALUATED USING 
A VIRTUAL REALITY PROGRAM AND THE BATTERY NEUROPSI” 
Protocol Approval ID: DI/24/501/04/37 
BACKGROUND 
​
Obesity is a chronic, systemic, and multifactorial disease that affects individuals across all age 
groups, ethnicities, and social classes, and is not limited to economically disadvantaged countries (1). 
In adults, obesity is typically assessed and classified using the Body Mass Index (BMI), calculated by 
dividing body weight in kilograms by height in meters squared (kg/m²). According to the World Health 
Organization (WHO), an individual is considered obese when their BMI is ≥ 30 kg/m². Obesity is 
further classified into three categories: grade I (30.0–34.9 kg/m²), grade II (35.0–39.9 kg/m²), and 
grade III, or morbid obesity (≥ 40.0 kg/m²) (2). 
Globally, obesity has reached epidemic proportions and is often referred to as “the epidemic of the 
21st century.” The WHO reports that more than 650 million people worldwide are affected by obesity 
(3), as noted in the World Obesity Atlas (2023). Projections estimate a 50% global increase by 2035 
(4). 
In Mexico, the National Health and Nutrition Survey (ENSANUT 2022) documented a sustained rise 
in overweight and obesity rates. Among children aged 5–11 years, prevalence increased by 7% 
between 2006 and 2020–2022. In adolescents aged 12–19, the rate rose from 24% to 41.1% over the 
same period. The trend continues into adulthood, with obesity being more prevalent among women 
(76.9%) than men (73.5%). Adults aged 40–60 years show the highest prevalence at 85%. 
As obesity rates continue to rise, the incidence of associated comorbidities has also increased, 
including diabetes mellitus, hypertension, dyslipidemia, cardiovascular disease, and certain types of 
cancer. Moreover, obesity has been linked to neurodegenerative conditions such as dementia (5). 
On the other hand, the WHO estimates that more than 46.8 million patients worldwide have 
neurodegenerative diseases, a figure that doubles every twenty years. In Mexico, approximately 
800,000 older adults suffer from some neurodegenerative disease with an incidence ranging from 
16.6 to 34.2 per 1000 inhabitants/year (6). The annual cost of dementia care per capita in Mexico can 
reach $6,157.00. 
Cognitive impairment represents an intermediate clinical state between normal cognition and 
dementia. Cognitive decline has been attributed to the normal aging process. However, several 
factors have been associated with the prevalence of cognitive impairment, among which we found the 
educational level, cardiovascular risk (high blood pressure and obesity) (7). 
Studies using murine models have described theories linking obesity to cognitive deterioration. Diets 
high in fat and carbohydrates, which commonly induce obesity, have been associated with cognitive 

impairment due to structural lesions observed in various brain regions, including the hypothalamus 
(8). Furthermore, research in rodents has shown that increased adiposity can alter brain structure and 
function through mechanisms such as synaptic loss, reduced dendritic spine density, and changes in 
microglial morphology. These alterations contribute to deficits in attention, information processing 
speed, and memory (9). 
Structural alterations in architecture have been reported in brain imaging studies, including neuronal 
atrophy in the gray matter of the temporal, frontal, and occipital cortices, as well as the hippocampus, 
thalamus, and midbrain, and a reduction in white matter. These damages suggest that obesity is 
associated with neuronal atrophy, regardless of the patient's chronological age. A decrease in 
regional blood flow was also observed in the prefrontal cortex, along with a reduction in the functional 
activity of cortical areas associated with episodic or sensory memory, working memory, or operational 
memory. However, it remains unclear whether this affects long-term memory (10). 
Alterations in brain function do not exclusively affect cognition, but also the capacity for 
understanding, expressing, and experiencing emotions (for example, emotional lability, bipolar 
disorders, etc.), as well as the very structure of personality (e.g., organic personality disorder) (11). 
Currently, there are general neuropsychological assessment batteries (Neuropsi Attention and 
Memory), which are a set of tests or elements that explore the main cognitive functions in a 
systematic form, to detect and classify the existence of brain damage (12). 
Bariatric surgery has become an increasingly common and effective intervention for achieving 
significant weight loss in individuals with morbid obesity. It is currently the most widely used and 
successful treatment for obesity, primarily because it reduces appetite, induces a negative energy 
balance, and promotes sustained weight loss. This weight reduction is closely associated with the 
remission of obesity-related comorbidities. Moreover, bariatric surgery has been linked to lower rates 
of mortality and morbidity, fewer hospitalizations, and a decreased need for pharmacological 
treatment (1). 
Following bariatric surgery, patients often exhibit a reduction in systemic inflammation and notable 
changes in adipokine profiles. Adipose tissue is now recognized not merely as an energy reservoir 
but as an active endocrine organ that synthesizes and secretes various adipokines, including leptin 
and insulin. 
Insulin plays a critical role in facilitating glucose uptake by most cells in the body; however, the 
brain—despite its high energy demands—does not require insulin for glucose transport. Nonetheless, 
insulin does reach the brain, particularly the hippocampus, where it binds to specific receptors and 
modulates synaptic plasticity mechanisms that underlie learning and memory processes. Likewise, 
leptin also exerts a significant influence on these synaptic mechanisms, contributing to the regulation 
of cognitive functions (10) (13). 

Several studies have demonstrated a relationship between adiposity and cognitive decline, showing 
that excessive body fat is associated with reduced cognitive performance and an increased risk of 
developing neurological disorders such as gray matter atrophy and Alzheimer’s disease (14). This 
relationship may help explain why reducing systemic inflammation can lead to cognitive improvement; 
however, the underlying physiological mechanisms remain incompletely understood. 
Furthermore, numerous studies have examined the association between preoperative mental health 
status and postoperative outcomes following bariatric surgery. These studies have consistently 
reported reductions in depressive symptoms, including lower frequency and severity of episodes, with 
significant improvements observed as early as six months post-surgery (15,16). In some cases, a 
decrease in antidepressant use of up to 18% has been documented at 12 and 36 months after 
surgery, with these improvements maintained for up to three years. In contrast, other mental health 
conditions—such as psychosis, stress-related disorders, post-traumatic stress disorder, and 
personality disorders—have shown no significant changes following the intervention (15). Despite the 
growing body of literature, the specific predictors of mental health improvement after bariatric surgery 
are not well established (16). 
The Longitudinal Assessment of Bariatric Surgery (LABS) study utilizes subjective data from 
standardized questionnaires and a cognitive battery of their own design, which evaluates attitudes, 
motivations, and needs, using the outcomes as predictors of post-operative improvement in 
attention/executive function and short-term memory (17). However, other studies focused on 
observing non-surgical and psychological factors acting as predictors of short- and long-term 
outcomes through a program of National Institute of Mental Health diagnostic interviews (Version 
III-R, DIS III-R) and the Structured Clinical Interview for DSM-IV Axis II personality disorders (Version 
2.0, SCID-II) (18). 
One of the most widely used instruments for assessing the overall cognitive functioning of a person is 
the "Neuropsi: Attention and Memory," which consists of a series of tests that evaluate orientation, 
attention, memory, language, visual perception, and executive functions. Neuropsi has been validated 
in the Latin American Spanish-speaking population and incorporates relevant cultural factors into its 
evaluation process (11). 
Another aspect to consider is the patient's quality of life after undergoing surgical obesity treatment 
(18) (19). Despite the multiple instruments designed to assess quality of life in this population, there is 
no consensus on the most suitable instrument to measure it (19). The battery BAROS (Bariatric 
Analysis and Reporting Outcome System) has been validated as the most comprehensive evaluation 
system and objective measure of the benefits of bariatric surgery, as it enables an objective 
evaluation and standardized assessment of changes in quality of life after bariatric surgery (20). 
Includes the Moorehead-Ardelt Quality of Life Questionnaire, developed specifically for patients 

undergoing surgical obesity treatment (20). This questionnaire consists of five questions about 
self-esteem, physical activity, social life, working, and sexual conditions (21). 
Today, Virtual Reality is a novel approach to cognitive and/or assessment. Patient rehabilitation is 
based on a dynamic three-dimensional simulation in which the user feels immersed in an artificial 
environment that they perceive as real based on stimuli of the sensory organs (22). Virtual Reality 
technology is based on numerous applications that employ the theory that knowledge is retained 
better when it is experienced directly, rather than when one sees or hears it. The basis of this theory 
is the concept of first-person knowledge, according to which an individual acquires most of their 
knowledge of daily life through natural, direct experiences, not reflective and subjective (23). 
Motivated by these considerations, the present project aims to evaluate the impact of bariatric surgery 
on cognitive performance across different domains by employing computational techniques based on 
virtual reality. The virtual reality platform used for this purpose is NeuroTracker X (NT), a software 
system developed and patented by CogniSens Innovation Inc. in collaboration with the Visual 
Psychophysics and Perception Laboratory at the University of Montreal, Canada. 
NeuroTracker involves a dynamic visual task in which participants are required to track specific target 
objects moving within a 3D virtual space among multiple identical distractors. Functional magnetic 
resonance imaging (fMRI) studies investigating the neural correlations of object tracking have shown 
activation in the frontal, parietal, and temporal brain regions, each associated with distinct cognitive 
functions. The frontal lobe contributes to movement processing, attention, planning, decision-making, 
language, and emotional regulation. The parietal lobe is involved in integrating sensory information 
and supporting reasoning, motivation, and behavior. Meanwhile, the temporal lobe plays a critical role 
in auditory processing, language recognition, and memory formation (24). NeuroTracker X has 
emerged as a valuable tool for assessing and enhancing the efficiency of neural networks underlying 
key cognitive processes such as working memory, attention, executive function, and processing 
speed.​
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Problem statement ​
Obesity is a chronic disease that is progressively increasing worldwide. It is estimated that 
approximately 38% of the world's adult population will be overweight by 2030. Adiposity is linked to 
cognitive impairment, reducing cognitive abilities and increasing the risk of developing neurological 
disorders such as brain gray matter atrophy and Alzheimer's disease.  
Bariatric surgery is an effective and increasingly popular method for weight loss among people with 
severe obesity. The loss of adipose tissue appears to have a positive effect on cognitive functioning; 
however, predictors of improvement are not yet well established. This study seeks to quantify the 
impact of bariatric surgery on cognitive function using virtual reality-based computing tools and 

evaluate the changes in quality of life after bariatric surgery.​
​
Justification 
Bariatric surgery is a set of surgical interventions designed to produce significant weight loss. It has 
also been the most widely used and successful procedure for treating obesity, as it produces a 
decrease in appetite in patients, causing the energy balance to become negative and thus leading to 
weight loss, which in turn is related to the remission of comorbidities. After bariatric surgery, a 
reduction in inflammation and changes in adipokines have been observed, indicating that the 
reduction of inflammation may improve cognition after bariatric surgery. Although there is scientific 
evidence indicating that the post-operative outcome of this group of patients has been even superior 
to the improvement achieved by lifestyle modifications and/or pharmacological therapy, the data are 
inconsistent (14). The use of computerized tools, Virtual Reality-based assessments, is a novel 
approach to cognitive and/or Patient rehabilitation. Using Neutrotracker (NT) and the Neuropsi 
Attention test and memory, this study seeks to evaluate the effect of bariatric surgery on performance 
in domains of post-operative cognitive impairment in patients from the Comprehensive Patient Care 
Clinic service with diabetes and obesity (CAIDO). 
​
Hypothesis 
Patients with obesity undergoing bariatric surgery will present statistically significant differences (p ≤ 
0.05) in their scores on the Neuro Tracker and the Neuropsi Attention and Memory battery before and 
after surgery. 
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Objectives: 
General  
Evaluate using virtual reality software (NeuroTracker) and the neuropsychological battery (Neuropsi 
Attention and Memory) improvements in the performance of cognitive domains of patients, candidates 
for bariatric surgery, before and after the surgical procedure. 
Secondary  
●​ Evaluate the cognitive performance of obese patients undergoing bariatric surgery 3 and 
6 months after the intervention through NT and Neuropsi Attention and Memory (the 
latter after 6 months to avoid the effect of learning the battery). 
●​ To study the impact of bariatric surgery on the quality of life of patients who underwent 
the intervention using the BAROS battery. 
 
 

Methodology 
Type and design of study: Quasi-experimental, prospective study. 
Population and sample size: 
The sample size was determined using the difference of means method for paired samples. The 
effect size used (Cohen's d) was 0.6575741 (25), with a two-tailed (bilateral) test at a 95% confidence 
level and 80% statistical power. With these characteristics, the sample size is 21 patients. 
The software used for determining the sample size was Gpower version 3.1.9.7. 
 
INCLUSION, EXCLUSION AND ELIMINATION CRITERIA. 
Inclusion Criteria 
A.​ Age (18-65 years) 
B.​ Diagnostic of morbid obesity with a body mass index (BMI) > 40 kg/m2, or, 
C.​ Obesity grade II (BMI > 35 kg/m2) and associated comorbidities (Diabetes Mellitus type 2, 
Hypertension, Ischemic Cardiopathy, Hyperlipidemia, Hepatic Steatosis, Metabolic Syndrome, 
Obstructive Sleep Apnea, Pickwick Syndrome) 
D.​ Bariatric surgery criteria. 
Exclusion Criteria 
A.​ Age < 18 years, > 65 years 
B.​ Visual impairment 
C.​ Personal history of CVE 
D.​ Drug addiction. 
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Variables 
VARIABLE  
TYPE 
OPERATIONAL 
DEFINITION 
UNIT OF 
MEASUREMENT 
 STATISTICAL 
ANALYSIS 
Sex 
Nominal  
Biological 
differences 
between males and 
females 
of 
a 
species, including 
differences 
in 
chromosomes and  
reproductive 
structures. 
Male/Female 
Frequencies 
% 
Age  
Nominal  
It is the time 
elapsed since birth. 
Years  
Frequencies 
% 
Body Mass 
Index 
(BMI) 
Quantitative 
A 
measure 
that 
assesses 
the 
relationship 
between a person's 
weight and height 
to determine their 
level of adiposity. 
Kg/m2  
Frequencies 
% 
Visual 
perception 
Quantitative 
Execution 
value: 
Stimulus detection 
threshold. 
Seconds 
Linear 
regression, 
Student's 
t-test, 
ANOVA, 
time-frequen
cy and 
multiscale 
entropy 

spectra 
Neuropsycholo
gical Battery: 
Attention and 
Memory 
Quantitative 
Score obtained on 
the Battery 
Neuropsychological 
Neuropsychology 
Attention and 
Memory. 
Normalized 
punctuation 
Student’s 
t-test 
NT  
Quantitative 
Tracking speed. 
m/s  
Linear 
Regression, 
Student's 
t-test, 
ANOVA 
Quality of Life 
Qualitative/
Quantitative 
A measure that 
assesses a 
person's overall 
well-being. 
Numeral  
Student’s 
t-test 
 
Information on the Neuropsi Neuropsychological Battery for Attention and Memory 
The Neuropsi Attention and Memory Neuropsychological Battery [11] is a compilation of tasks most 
used in neuropsychological literature to assess attention and memory (verbal and visual, both in its 
encoding and recall modes). It also includes subtests that allow for the assessment of executive 
functioning. It was developed in a Spanish-speaking Latin American population, so it takes important 
cultural aspects into account in its implementation. 
It has a total of 17 profiles and three educational levels: low (0-3 years of schooling), medium (4-9 
years), and high (10-24 years). 
To assess skills and disabilities, it has a total of 29 subtests that are converted into normalized scores 
with a mean of 10 and a standard deviation of 3. The battery allows obtaining two partial scores, one 
from the Attention subdivision and another from memory, with a third factor being the total score 
(Attention and Memory). Neuropsi allows a classified score into one of the following levels of 
alteration: 1) high normal, 2) normal, 3) mild alterations, 4) severe alterations. 
 
 

 
 
The test is administered individually and lasts approximately 1.5 hours. 
NEUROPSI: NEUROPSYCHOLOGICAL ASSESSMENT TEST 
Author 
Dr. Feggy Ostrosky-Solis 
Aim  
Evaluates cognitive functioning in the attention and memory areas. 
Provides a quantitative and objective assessment of these key 
cognitive functions. 
Application 
Context 
Clinics, hospitals, doctor's offices and neuropsychological research 
centers. 
Description  
A brief neuropsychological test for assessing various cognitive 
domains (e.g., attention, memory, language, perception, and 
executive functions). 
Procedure  
Individual administration and subtests application following the 
established protocol. 
Target Population  
Mexican population, considering age and educational level. 
Duration 
90 minutes (1 hour and 30 minutes). 
Material  
Application Manual, Record Form/Protocol, Pencil and Paper. 
Scoring and 
Interpretation 
Each subtest is scored, and composite scores are obtained for each 
cognitive domain. These can be interpreted using z-scores or 
percentiles. 
Advantages  
This test allows for the identification of alterations or 
difficulties in attention and memory. It can be applied in a 
group or individually. 
It is suitable for any clinical setting with patients who have 
suffered or are suffering from an illness (e.g., stroke, 
Alzheimer's, schizophrenia, neurodevelopmental disorders, 

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Technical information about the training programs and devices to be used NeuroTracker (NT): 
NeuroTracker (NT) is a computer tool that assigns cognitive tasks involving multiple visual tracking of 
3D objects on the screen, under increasing difficulty. Each training session consists of a series of 
mini-tests where the patient needs to remember the target objects and follow their movement among 
distractors for several seconds before identifying them.  
NT is a product validated and patented by the Cogni Sens Applied Research Center (ARC), which 
has been used in Hospitals, Specialized Care Centers, and centers specialized in vision, schools, and 
the general population. 
We will use the rate threshold protocol NeuroTracker (NT), established under only one condition: 
tracking 4 targets. Each block (referred to as a “ladder”) will last approximately 10 minutes. 
Participants will complete three sets of ladders in one session, for a total duration of 30 minutes. Each 
block has five phases (see Figure 1). 
 
Figure 1. 5 Phases of NT. 
●​ Phase 1, presentation: Eight static balls are presented for 2.5 s in random positions. 
●​ Phase 2, indexing: Four red spheres for 2 seconds for target identification, before 
returning to their original color. 
●​ Phase 3, tracking: all spheres begin to move in random directions at the speed defined 

by the staircase procedure (see below), bouncing between them and with the virtual 
walls for 8 seconds. 
●​ Phase 4, identification: the spheres stop moving, each one has a label of unique 
identification from 1 to 8. The task of the participants is to identify the 3 numbers 
corresponding to the three target spheres that had been indexed. 
●​ Phase 5, feedback: feedback is given, showing the observer the spheres which were 
initially indexed. Speed thresholds will be evaluated using an ascending ladder 
procedure, that is, after a response is correct, the displacement of the ball's speed will 
increase by 0.05 units. record and will decrease in the same proportion after each 
incorrect answer, resulting in a threshold criterion of 50%. The ladder is interrupted after 
eight investments, and the threshold is estimated by the geometric mean velocity of the 
last four inversions. The initial virtual velocity is set at 3.75 cm/s. To obtain a correct 
answer, participants must report all objectives correctly. 
 
Instrument for measuring Quality of Life using (BAROS) 
BAROS (Bariatric Analysis and Reporting Outcome System) is an instrument that permits the 
objective and standardized evaluation of changes in the quality of life of patients undergoing bariatric 
surgery. 
This evaluation includes the validated Moorehead-Ardelt Quality of Life Questionnaire, specifically 
designed for this population. The questionnaire consists of 5 simple questions aimed at measuring 
self-esteem, physical activity, social life, working, and sexual conditions. 
Each question offers five answer choices with illustrations, scored from -1 to +1 points depending on 
whether it worsens, remains the same, or improves. This approach yields a total score between -3 
and +3, which is incorporated into the comprehensive evaluation conducted by the BAROS system. 
The Moorehead-Ardelt questionnaire is brief, easy to understand, and easy to complete. Autonomous 
monitoring by the patient enables independent quantification of potential changes in five key areas 
related to quality of life after surgical treatment. In this way, the instrument provides an objective and 
comparable measure of the effects of subjective aspects of bariatric surgery from the patient's own 
perspective. Their results form an integral part of the overall ranking, which is based on the system's 
assessment of the achieved results. 
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Procedure 
Once the group has been identified, the patients who meet the inclusion criteria proceed with the 
visits described below:  

1.​ 1) Visit 1. Explanation of the project for your subsequent informed consent, data 
recording, and application of the Neuropsi Attention and Memory battery. 
2.​ 2) Visit 2. Application of the BAROS Battery and Neurotracker for four sessions. 
3.​ In the first session, the dynamics of the virtual reality program are explained to the 
subject, with a trial session (5-10 minutes). Each subject performs 4 NT sessions per 
day until completing a total of 12 sessions. You will need to use the Virtual Reality 
equipment three times a day for two weeks before bariatric surgery. 
4.​ Visit 3. Neurotracker application four sessions. 
5.​ Visit 4: Neurotracker application four sessions. 
6.​ Visit 5: Bariatric Surgery is performed. 
7.​ Visit 6 (3 months after bariatric surgery): Neurotracker 4 application sessions and 
BAROS battery. After bariatric surgery (at 3 and 6 months). A new NT assessment will 
be applied at a rate of 12 sessions with a duration of each one approximately 20 
minutes. 
8.​ Visit 7 (3 months after bariatric surgery): Neurotracker 4 application sessions. 
9.​ Visit 8 (3 months after bariatric surgery): Neurotracker 4 application sessions. 
10.​Visit 9 (6 months after bariatric surgery): Neuropsi Battery Application Attention and 
Memory. 
11.​Visit 10 (6 months after bariatric surgery): Neurotracker 4 application, BAROS sessions, 
and drums. 
12.​Visit 11 (6 months after bariatric surgery): Neurotracker 4 application sessions. 
13.​Visit 12 (6 months after bariatric surgery): Neurotracker 4 application sessions. 
Location: Comprehensive Diabetes and Obesity Care Clinic (CAIDO) located in Pavilion 401-PB, of 
the Outpatient Clinic, and in the laboratory of the Research Unit and Technological Development 
(UDIT) located in Unit 110 between Internal Medicine and Geriatrics from the General Hospital of 
Mexico. Duration per visit: approx. 1:30 hrs.​
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Flowchart 
 
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Schedule of activities 
 
 
Statistical analysis 
Statistical analysis will be performed using SPSS statistical software. The results obtained will be 
interpreted in consideration of the statistical significance values (p < 0.05) and the corresponding 
confidence intervals. 
Descriptive statistics will be performed for all variables, calculating means and standard deviations. 
Standard, medians, and interquartile ranges, frequencies, and proportions depending on the type of 
variable. To evaluate the improvement, comparisons will be made using the difference of means with 
Student's t-test (before and after bariatric surgery). In the case of the variables, Qualitative 
assessments will include a chi-square test (X2) before and after bariatric surgery in all evaluations 
and follow-up. Additionally, a pre- and post-bariatric surgery comparison will be conducted to assess 
the differences in performance between the Neuropsi, BAROS, and Neurotracker tests. 
Ethical and biosecurity aspects 
NeuroTracker is a proven computer-based cognitive training tool. Normal and laboratory conditions 
require nothing more than subjects being seated. In this way, the tool poses no danger to the 
participants' health. Therefore, this investigation is classified as minimal risk according to Article 17 of 
the International Guidelines for Good Medical Practice and Research, as it employs non-invasive 
techniques and cognitive testing. Therefore, integrity will not affect the physical health of the patients. 
This study will be based on the three ethical principles of justice, non-maleficence, and beneficence, 
in accordance with the provisions of the National Commission for the Protection of Human Subjects, 
in the context of Biomedical and behavioral research. 
The informed consent form will be utilized to ensure that each individual who enters the protocol 

understands and authorizes their participation; those who do not sign will be excluded from 
participation. 
Relevance and expectations 
The project’s relevance lies in its focus on obesity and its association with cognitive deterioration. 
While several previous studies have attempted to evaluate this association subjectively through tests 
that often depend on the observer's perspective, our approach is different. The use of new 
technologies allows for an objective and non-invasive evaluation of Multiple Objects Tracking (MOT) 
performance. This will enable us to identify whether the effect of bariatric surgery helps improve 
cognition and quality of life in patients who have undergone the intervention. In this context, the 
Hospital General de México supports the use of this new type of intervention. Technologies such as 
the Neuro Tracker (NT) are gaining significant relevance; this project also aims to position the NT as 
a transferable tool to other health institutions in the country. 
Available resources 
The Comprehensive Care Clinic for Diabetes and Obesity (CAIDO) at HGM has the required 
population for this research protocol. 
Support from bariatric physicians who perform the evaluation, providing a clinical diagnosis, to the 
patients. Likewise, the space and support of the UIDT researchers are available at HGM.  
The Applied Research Center of Cognisens Inc. will grant some licenses free of charge, exclusive to 
the use of NeuroTracker (NT) for the duration of the study, with the possibility of renewal by prior 
agreement between the parties.. 
Resources to be acquired 
The materials to be acquired include file materials, such as A4 paper sheets, a pencil, and an eraser. 
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