A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effect of the Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Male Subjects
Phase: PHASE1
Conditions: Healthy, Male
Sponsor: BeiGene

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I have read the protocol “A Phase 1, Open-label, Fixed-sequence Study to Investigate the 
Effect of the Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in 
Healthy Male Subjects” and approve it: 
 
 
 
 
 
 
Date 
BeiGene, Ltd. 
 
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