Feasibility of Adapted Physical Activity Based on a Walking Platform in Hospitalized Old Patients for Cancer
Phase: NA
Conditions: Oncology, Adapted Physical Activity
Sponsor: Centre Francois Baclesse

 
Synopsis APPAHoCa  N°IDRCB: 2018-A00031-54  - Version n° 2.1 du 07/10/2018  
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SYNOPSIS APPAHOCA study 
 
 
 
Feasibility of adapted physical activity based on a walking platform for elderly patients 
hospitalized for cancer 
 
ID-RCB: 2018-A00031-54 
 
Version n°2.1 07/10/2018 
 
 
 
SPONSOR 
Centre François Baclesse 
3 avenue du Général Harris 
14076 CAEN cedex 5 
 
COORDINATING 
INVESTIGATORS 
Dr Bérengère BEAUPLET 
CHU - Avenue Côte de Nacre 
14033 CAEN Cedex 
 
Dr Heidi SOLEM LAVIEC  
Centre François Baclesse  
Boulevard du Général Harris  
14000 CAEN  
 
 
REGULATORY 
APPROVALS 
CPP IDF 5 
Date: 06/03/2018 
 
 
 

 
Synopsis APPAHoCa  N°IDRCB: 2018-A00031-54  - Version n° 2.1 du 07/10/2018  
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TITLE 
Feasibility of adapted physical activity based on a walking platform for elderly 
patients hospitalized for cancer 
ACRONYM 
APPAHOCA 
Coordinator 
Dr Bérengère BEAUPLET 
Indication 
Elderly patients hospitalized for cancer 
Test 
methodology 
Multicenter, prospective, non-randomized, open-label pilot feasibility study 
Objectives 
Main objective 
Assess the feasibility of adapted physical activity (APA) based on a walking platform 
in patients aged 70 and over hospitalized for cancer.  
Secondary objectives 
▪ 
Describe adherence to adapted physical activity, in quantitative and 
qualitative terms 
▪ 
Investigate factors associated with adherence: oncological factors, social 
factors, previous mobility, cognitive level, comorbidities 
▪ 
Assess patient satisfaction with using an adapted walking platform 
Judgment 
criteria 
 
Main criteria 
▪ 
Percentage of patients included who complete at least two sessions of 6 
minutes or more of adapted physical activity on the walking platform. 
Adapted physical activity on a walking platform will be considered feasible if 
≥70% of patients complete ≥2 sessions of 6 minutes or more during their 
hospitalization for cancer lasting ≥48 hours. 
Secondary criteria 
Patient adherence to adapted physical activity will be assessed: 
•    Quantitatively (intensity of participation): number and duration of sessions, 
number and regularity of steps, maximum and average walking speed, distance 
covered 
•    Qualitatively: 
o    Reason for not completing the first and/or second session, 
o    Type of activity: use of balance games, chosen visual walking route  
 
 
Factors that may be associated with adherence: 
•    Gender, age, socio-professional category before retirement 
•    Location of cancer, reasons for hospitalization (medical or surgical) 
•    Pain 
•   Activity before hospitalization: Performance Status, previous QAPPA activity 
level, history of falls in the past year 
•  Cognitive status prior to the first session: memory test (temporal-spatial 
orientation/10, learning and  recalling 3 words) 
•    Activity prior to the first session: Ability to walk 4 meters (alone/with technical 
and/or human assistance) and time required; Ability to transfer (alone/with 
technical and/or human assistance); Physical therapy already underway 
•    Context, presence of severe comorbidity(ies) affecting mobility, presence of 
isolation due to multi-resistant bacteria, presence of medical equipment (IV, drain, 
urinary catheter, enteral feeding tube, ostomy bag, oxygen therapy glasses) 
 
Patient satisfaction with the use of the adapted walking platform will be 
assessed at each session on a scale of 0 to 10 on the following items: 
• Fear of falling 

 
Synopsis APPAHoCa  N°IDRCB: 2018-A00031-54  - Version n° 2.1 du 07/10/2018  
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• Use of the treadmill 
• Satisfaction with the digital tablet on the walking platform 
• Instructional support from the APA educator (starting from the second 
session) 
Inclusion 
criteria 
- 
Patients with cancer 
- 
Patients over the age of 70 hospitalized for 48 hours or more 
- 
Patients identified as eligible for a medical prescription for APA 
- 
Proficiency in French 
- 
Patients affiliated with a social security system 
- 
Patients who have given their written consent 
Exclusion 
criteria 
 
- 
Patients who are completely unable to communicate 
- 
Patients receiving palliative care in the terminal phase 
- 
Patients who are less than 1.35 m or more than 2 m tall and/or weigh more 
than 130 kg 
- 
Patients who are unable to participate in APA sessions 
- 
Patients who are unable to wear a support harness 
- 
Patients deprived of their liberty or under guardianship 
- 
Patients unable to comply with the requirements of the protocol for 
geographical, social, or psychopathological reasons 
Description 
of the 
protocol/exp
erimental 
design 
After checking the patient's ability to participate in walking sessions and obtaining a 
medical prescription, the physical activity instructor will ask patients questions about 
their usual activities prior to hospitalization.  
During the patient's hospitalization, physical activity on the adapted ema® walking 
platform will be offered every working day, in the form of a session lasting a 
minimum of 6 minutes and a maximum of 30 minutes. 
The walking sessions will be carried out on an adapted walking platform, comprising 
a treadmill and a connected tablet. The tablet allows patients to view a landscape or 
play balance or memory games while walking. The activity offered will be tailored to 
the patient's profile. 
Patients will be brought to the platform in a wheelchair and returned to their room by 
the same means of transport. 
At the end of each session, patients will complete a satisfaction questionnaire. 
Number of 
subjects 
To estimate a proportion of 70% of patients with a 95% confidence interval of [45-
95], it is necessary to include 50 evaluable patients. To anticipate potential non-
evaluable patients, we plan to include 60 patients. 
Participating 
centers  
2  
Study 
duration 
6 months