Study to Evaluate the Efficacy and Safety of CardiolRx™ in Patients With COVID-19 and Cardiovascular Disease or Risk Factors A Double-blind, Placebo-controlled Trial
Phase: PHASE2
Conditions: COVID-19, Cardiovascular Diseases, Cardiovascular Risk Factor
Sponsor: Cardiol Therapeutics Inc.

	
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COMBINED LIST OF DRUGS THAT PROLONG QT AND/OR CAUSE TORSADES DE POINTES (TDP)
CredibleMeds® has reviewed available evidence for the drugs on the following list and 
place them in one of three designated categories: Known Risk of TdP (KR), Possible Risk 
of TdP (PR) or have a Conditional Risk of TdP (CR). The full description of these 
categories can be found on the CredibleMeds.org website.
Generic Name
Brand Name
Abarelix (PR)
Plenaxis
Abiraterone (CR)
Zytiga and others
Aclarubicin (KR)
Aclacin and others
Alfuzosin (PR)
Uroxatral
Alimemazine 
(Trimeprazine) (PR)
Nedeltran and others
Amantadine (CR)
Symmetrel and others
Amiodarone (KR)
Cordarone and others
Amisulpride (CR)
Barhemsys and others
Amitriptyline (CR)
Elavil (Discontinued 
6/13) and others
Amphotericin B (CR)
Fungilin and others
Amsacrine (Acridinyl 
anisidide) (CR)
Amsidine
Anagrelide (KR)
Agrylin and others
Apalutamide (PR)
Erleada
Apomorphine (PR)
Apokyn and others
Aripiprazole (PR)
Abilify and others
Arsenic trioxide (KR)
Trisenox
Artemether/Lumefantrine 
(PR)
Coartem
Artenimol/piperaquine (PR)
Eurartesim
Asenapine (PR)
Saphris and others
Astemizole (KR)
Hismanal
Atazanavir (CR)
Reyataz and others
Atomoxetine (PR)
Strattera
Generic Name
Brand Name
Azithromycin (KR)
Zithromax and 
others
Bedaquiline (PR)
Sirturo
Bendamustine (PR)
Treanda and others
Bendroflumethiazide 
(Bendrofluazide) 
(CR)
Aprinox and others
Benperidol (PR)
Anquil and others
Bepridil (KR)
Vascor
Betrixaban (PR)
Bevyxxa
Bortezomib (PR)
Velcade and others
Bosutinib (PR)
Bosulif
Buprenorphine (PR)
Butrans and others
Cabozantinib (PR)
Cometriq
Capecitabine (PR)
Xeloda
Carbetocin (PR)
Pabal and others
Ceritinib (PR)
Zykadia
Cesium Chloride 
(KR)
Energy Catalyst
Chloral hydrate (CR)
Aquachloral and 
others
Chloroquine (KR)
Aralen
Chlorpromazine (KR)
Thorazine and 
others
Chlorprothixene (KR)
Truxal
Cilostazol (KR)
Pletal
Cimetidine (CR)
Tagamet
Ciprofloxacin (KR)
Cipro and others
Generic Name
Brand Name
Cisapride (KR)
Propulsid
Citalopram (KR)
Celexa and others
Clarithromycin (KR)
Biaxin and others
Clofazimine (PR)
Lamprene
Clomipramine (CR)
Anafranil
Clotiapine (PR)
Entumine
Clozapine (PR)
Clozaril and others
Cobimetinib (PR)
Cotellic
Cocaine (KR)
Cocaine
Crizotinib (PR)
Xalkori
Cyamemazine 
(Cyamepromazine) (PR)
Tercian
Dabrafenib (PR)
Tafinlar
Dasatinib (PR)
Sprycel
Degarelix (PR)
Firmagon and 
others
Delamanid (PR)
Deltyba
Desipramine (PR)
Pertofrane and 
others
Deutetrabenazine (PR)
Austedo
Dexmedetomidine (PR)
Precedex and 
others
Dextromethorphan/Quinidine 
(PR)
Nuedexta
Diphenhydramine (CR)
Benadryl and 
others
Disopyramide (KR)
Norpace
Dofetilide (KR)
Tikosyn
If list is printed, check website at www.crediblemeds.org   •   Please see Disclaimer below   •   List continued over        
	
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RDIOL 
THERAPEUTICS 
CREDIBLEMEos® 

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Generic Name
Brand Name
Dolasetron (PR)
Anzemet
Domperidone (KR)
Motilium and others
Donepezil (KR)
Aricept
Doxepin (CR)
Sinequan and others
Dronedarone (KR)
Multaq
Droperidol (KR)
Inapsine and others
Efavirenz (PR)
Sustiva
Eliglustat (PR)
Cerdelga
Encorafenib (PR)
Braftovi
Entrectinib (PR)
Rozlytrek
Eperisone (CR)
Myonal and others
Epirubicin (PR)
Ellence and others
Eribulin mesylate (PR)
Halaven
Erythromycin (KR)
E.E.S. and others
Escitalopram (KR)
Cipralex and others
Esomeprazole (CR)
Nexium and others
Ezogabine (Retigabine) 
(PR)
Potiga and others
Famotidine (CR)
Pepcid and others
Felbamate (PR)
Felbatol
Fingolimod (PR)
Gilenya
Flecainide (KR)
Tambocor and others
Fluconazole (KR)
Diflucan and others
Fluorouracil (5-FU) (PR)
Adrucil and others
Fluoxetine (CR)
Prozac and others
Flupentixol (PR)
Depixol and others
Fluvoxamine (CR)
Faverin and others
Furosemide (frusemide) 
(CR)
Lasix and others
Galantamine (CR)
Reminyl and others
Generic Name
Brand Name
Garenoxacin (CR)
Geninax
Gatifloxacin (KR)
Tequin
Gemifloxacin (PR)
Factive
Gilteritinib (PR)
Xospata
Glasdegib (PR)
Daurismo
Granisetron (PR)
Kytril and others
Grepafloxacin (KR)
Raxar
Halofantrine (KR)
Halfan
Haloperidol (KR)
Haldol and others
Hydrochlorothiazide (CR)
Apo-Hydro and others
Hydrocodone - ER (PR)
Hysinglaâ„¢ ER and others
Hydroquinidine 
(Dihydroquinidine) (KR)
Serecor
Hydroxychloroquine (KR)
Plaquenil and others
Hydroxyzine (CR)
Atarax and others
Ibogaine (KR)
Ibutilide (KR)
Corvert
Iloperidone (PR)
Fanapt and others
Imipramine (Melipramine) 
(PR)
Tofranil
Indapamide (CR)
Lozol and others
Inotuzumab ozogamicin (PR)
Besponsa
Isradipine (PR)
Dynacirc
Itraconazole (CR)
Sporanox and others
Ivabradine (CR)
Procoralan and others
Ivosidenib (PR)
Tibsovo
Ketanserin (PR)
Sufrexal
Ketoconazole (CR)
Nizoral and others
Lacidipine (PR)
Lacipil and others
Lansoprazole (CR)
Prevacid and others
Generic Name
Brand Name
Lapatinib (PR)
Tykerb and others
Lefamulin (PR)
Xenleta
Lenvatinib (PR)
Lenvima
Leuprolide (Leuprorelin) (PR)
Lupron and others
Levofloxacin (KR)
Levaquin and others
Levomepromazine 
(Methotrimeprazine) (KR)
Nosinan and others
Levomethadone 
(levamethadone) (PR)
Levomethadyl acetate (KR)
Orlaam
Levosulpiride (KR)
Lesuride and others
Lithium (PR)
Eskalith and others
Lofexidine (PR)
Lucemyra
Loperamide (CR)
Imodium
Lopinavir/Ritonavir (PR)
Kaletra and others
Lumateperone (PR)
Caplyta
Lurasidone (PR)
Latuda
Maprotiline (PR)
Ludiomil
Melperone (PR)
Bunil and others
Memantine (PR)
Namenda XR
Mesoridazine (KR)
Serentil
Methadone (KR)
Dolophine and others
Metoclopramide (CR)
Reglan and others
Metolazone (CR)
Zytanix and others
Metronidazole (CR)
Flagyl
Mianserin (PR)
Tolvon
Midostaurin (PR)
Rydapt
Mifepristone (PR)
Korlym and others
Mirabegron (PR)
Myrbetriq
Mirtazapine (PR)
Remeron
If list is printed, check website at www.crediblemeds.org   •   Please see Disclaimer below   •   List continued over        
	
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RDIOL 
THERAPEUTICS 

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Generic Name
Brand Name
Moexipril/Hydrochlorothiazide 
(PR)
Uniretic and others
Moxifloxacin (KR)
Avelox and others
Necitumumab (PR)
Portrazza
Nelfinavir (CR)
Viracept
Nicardipine (PR)
Cardene
Nifekalant (KR)
Shinbit
Nilotinib (PR)
Tasigna
Norfloxacin (PR)
Noroxin and others
Nortriptyline (PR)
Pamelor and others
Nusinersen (PR)
Spinraza
Ofloxacin (PR)
Floxin
Olanzapine (CR)
Zyprexa and others
Omeprazole (CR)
Losec and others
Ondansetron (KR)
Zofran and others
Osilodrostat (PR)
Isturisa
Osimertinib (PR)
Tagrisso
Oxaliplatin (KR)
Eloxatin
Oxytocin (PR)
Pitocin and others
Paliperidone (PR)
Invega and others
Palonosetron (PR)
Aloxi
Panobinostat (PR)
Farydak
Pantoprazole (CR)
Protonix and others
Papaverine HCl (Intra-coronary) 
(KR)
Paroxetine (CR)
Paxil and others
Pasireotide (PR)
Signifor
Pazopanib (PR)
Votrient
Pentamidine (KR)
Pentam
Perflutren lipid microspheres (PR)
Definity and others
Perphenazine (PR)
Trilafon and others
Pilsicainide (PR)
Sunrythm
Pimavanserin (PR)
Nuplazid
Pimozide (KR)
Orap
Pipamperone (PR)
Dipiperon and others
Generic Name
Brand Name
Piperacillin/Tazobactam 
(CR)
Tazosyn and others
Pitolisant (Tiprolisant) (PR)
Wakix
Posaconazole (CR)
Noxafil and others
Pretomanid (PR)
Primaquine phosphate (PR)
Probucol (KR)
Lorelco
Procainamide (KR)
Pronestyl and others
Promethazine (PR)
Phenergan
Propafenone (CR)
Rythmol SR and others
Propofol (KR)
Diprivan and others
Prothipendyl (PR)
Dominal and others
Quetiapine (CR)
Seroquel
Quinidine (KR)
Quinaglute and others
Quinine sulfate (CR)
Qualaquin and others
Ranolazine (CR)
Ranexa and others
Ribociclib (PR)
Kisqali
Rilpivirine (PR)
Edurant and others
Risperidone (CR)
Risperdal
Romidepsin (PR)
Istodax
Roxithromycin (KR)
Rulide and others
Rucaparib (PR)
Rubraca
Saquinavir (PR)
Invirase(combo)
Selpercatinib (PR)
Retevmo
Sertindole (PR)
Serdolect and others
Sertraline (CR)
Zoloft and others
Sevoflurane (KR)
Ultane and others
Siponimod (PR)
Mayzent
Solifenacin (CR)
Vesicare
Sorafenib (PR)
Nexavar
Sotalol (KR)
Betapace and others
Sparfloxacin (KR)
Zagam
Sulpiride (KR)
Dogmatil and others
Sultopride (KR)
Barnetil and others
Generic Name
Brand Name
Sunitinib (PR)
Sutent
Tacrolimus (PR)
Prograf and others
Tamoxifen (PR)
Nolvadex and others
Tazemetostat (PR)
Tazverik
Telaprevir (CR)
Incivo and others
Telavancin (PR)
Vibativ
Telithromycin (PR)
Ketek
Terfenadine (KR)
Seldane
Terlipressin (KR)
Teripress and others
Terodiline (KR)
Micturin and others
Tetrabenazine (PR)
Nitoman and others
Thioridazine (KR)
Mellaril and others
Tiapride (PR)
Tiapridal and others
Tipiracil/Trifluridine (PR)
Lonsurf
Tizanidine (PR)
Zanaflex and others
Tolterodine (PR)
Detrol and others
Toremifene (PR)
Fareston
Torsemide (Torasemide) 
(CR)
Demadex and others
Tramadol (PR)
Crispin and others
Trazodone (CR)
Desyrel and others
Trimipramine (PR)
Surmontil and others
Tropisetron (PR)
Navoban and others
Valbenazine (PR)
Ingrezza
Vandetanib (KR)
Caprelsa
Vardenafil (PR)
Levitra
Vemurafenib (PR)
Zelboraf
Venlafaxine (PR)
Effexor and others
Voriconazole (CR)
VFend
Vorinostat (PR)
Zolinza
Ziprasidone (CR)
Geodon and others
Zotepine (PR)
Losizopilon and others
Zuclopenthixol 
(Zuclopentixol) (PR)
Cisordinol and others
Note: Medicines on this list are reviewed on an ongoing basis to assure that the available evidence supports their continued placement on this list. Because, the list changes regularly, we 
recommend always checking the website at crediblemeds.org for the most up-to-date information. Most drugs have multiple brand names and it is not practical to list them on this form. The 
CredibleMeds.org website provides a partial list of the more common brands. 
Disclaimer and Waiver: The information presented here is intended solely for the purpose of providing general information about health-related matters. It is not intended for any other 
purpose, including but not limited to medical advice and/or treatment, nor is it intended to substitute for the users’ relationships with their own health care providers. To that extent, by use of 
this list and the information it contains, the user affirms the understanding of the purpose and releases AZCERT, Inc. from any claims arising out of his/her use of this list. The Terms of Use 
Agreement for this list and the CredibleMeds website is available at https://www.crediblemeds.org/terms. The absence of drugs from these lists should not be considered an indication that 
they are free of risk of QT prolongation or torsades de pointes. Few medicines have been tested for this risk in patients, especially those with congenital long QT syndrome. This list and the 
CredibleMeds® website are intended for personal and professional use only and are protected by U.S. Copyright (title 17, U.S. Code). Unauthorized commercial use is prohibited.
     Generated: August 11, 2020.     List last revised: May 12, 2020
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