A Prospective, Single-Center, Interventional Study to Evaluate the 5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical Performance and Reducing Injury Risk
Phase: NA
Conditions: Healthy
Sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

​BPIT_2024_StudyProtocol_v1​
​2024-BPIT (Balanced Progression Intensity Training) Study Report​
​2024​
​(DOI: 10.5281/zenodo.17551763)​
​Study Title: A Prospective, Single-Center, Interventional Study to Evaluate the​
​5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical​
​Performance and Reducing Injury Risk​
​Protocol ID: BPIT-GFFI-2024-001​
​ClinicalTrials.gov Identifier: NCT[pending]​
​Zenodo DOI: DOI: 10.5281/zenodo.17551763​
​Sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics​
​Research Inc.​
​Study Period: July 2024 – November 2024​
​Principal Investigator: Dr. Neeraj Mehta, PhD (Biomechanics & Alternative​
​Medicine)​
​Study Site: GFFI Fitness Academy​
​Affiliated Organizations: AIHFT.org, IIKBS.org​
​Report Date: November 30, 2024​
​BPIT Pilot v1.0​

​Study Title: A Prospective, Single-Center,​
​Interventional Study to Evaluate the 5-Line Principle of​
​Balanced Intensity Training (BPIT) for Enhancing​
​Physical Performance and Reducing Injury Risk​
​Protocol ID:​​BPIT-GFFI-2024-001​​ClinicalTrials.gov​​Identifier:​​NCT[pending]​​Sponsor:​
​MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.​​Study​
​Period:​​July 2024 - November 2024​​Principal Investigator:​​Dr. Neeraj Mehta, PhD​
​(Biomechanics & Alternative Medicine)​​Study Site:​​GFFI Fitness Academy​​Affiliated​
​Organizations:​​AIHFT.org, IIKBS.org​​Report Date:​​November​​30, 2024​
​EXECUTIVE SUMMARY​
​This prospective, single-center, interventional study evaluated the efficacy of the​​5-Line​
​Principle of Balanced Intensity Training (BPIT)​​in​​improving physical performance and​
​reducing injury risk over a 6-week training period.​
​●​ ​Participants:​​Twenty-three participants (18 males​​aged 22-48 years, 5 females aged​
​20-33 years) completed the study with a mean adherence rate of 94.9\%.​
​●​ ​Key Findings:​​The BPIT protocol demonstrated statistically​​significant improvements​
​across all measured outcomes, including:​
​○​ ​Strength gains of 15-25\%.​
​○​ ​Enhanced autonomic function (HRV increase of 12.67\text{ ms}).​
​○​ ​Improved biomechanical efficiency (knee valgus reduction of 17.9\%).​
​○​ ​A low injury incidence rate of 4.3\%.​
​●​ ​Conclusion:​​These findings support the BPIT method​​as an effective and safe training​
​approach for diverse populations.​
​1. INTRODUCTION​
​1.1 Background​
​Traditional strength training often leads to plateaus, overtraining, and increased injury risk. The​
​BPIT, developed by Dr. Neeraj Mehta, cycles through five distinct levels of exercise intensity to​
​optimize neuromuscular adaptation, enhance recovery, and minimize biomechanical stress.​
​●​ ​Line 1:​​Ground-Based, Low Intensity​
​●​ ​Line 2:​​Knee-Level, Low-Moderate Intensity​
​●​ ​Line 3:​​Standing, Moderate Intensity​
​●​ ​Line 4:​​Head-Level, Moderate-High Intensity​
​●​ ​Line 5:​​Plyometric/High-Impact, High Intensity​
​1.2 Study Rationale​
​BPIT Pilot v1.0​

​This study provides the first formal evaluation of the BPIT protocol in a structured research​
​setting.​
​1.2 ClinicalTrials.gov & DOI​
​This study is registered on ClinicalTrials.gov under the identifier​​NCT[pending]​. A Digital Object​
​Identifier (DOI) will be assigned upon formal publication:​
​DOI: [To be inserted post-registration]​. I.e. Zenodo​​DOI: 10.5281/zenodo.[pending]​
​1.3 Study Objectives​
​●​ ​Primary Objective:​​To assess the efficacy of the 6-week​​BPIT protocol in improving​
​maximal strength (1RM) and reducing the incidence of training-related injuries.​
​●​ ​Secondary Objectives:​​To evaluate the impact on heart​​rate variability (HRV), heart rate​
​recovery (HRR), muscle activation patterns (EMG), and joint biomechanics (knee valgus,​
​spinal curvature).​
​2. METHODS​
​2.2 Participants​
​Twenty-three healthy adults were enrolled.​
​Table 1: Participant Demographics​
Characteristic​
Value​
Total Participants​
23​
Males​
18 (78.3\%)​
Females​
5 (21.7\%)​
Mean Age \pm SD​
35.2\pm8.4 years​
Mean BMI (Baseline) \pm SD​
24.8\pm3.1\text{ kg/m}^2​
​2.4 Intervention​
​The BPIT protocol involved three 60-minute sessions per week for six weeks. Each session​
​progressed through the five intensity lines with auto-regulated rest intervals.​
​2.5 Outcome Measures​
​●​ ​Primary:​​Change in 1RM (squat, bench press, deadlift);​​Incidence of training-related​
​injuries.​
​●​ ​Secondary:​​Change in HRV (RMSSD); Change in HRR; Change​​in EMG (rectus​
​abdominis, quadriceps); Change in knee valgus angle and spinal curvature.​
​3. RESULTS​
​BPIT Pilot v1.0​

​3.1 Participant Flow and Adherence​
​●​ ​All 23 enrolled participants completed the intervention.​
​●​ ​Mean adherence was 94.9\%.​
​3.2 Primary Outcomes​
​3.2.1 Strength Improvements​
​Strength gains ranged from 15\% to 25\%.​
​Table 2: Strength Outcomes (1RM) - Mean Change (kg)​
Exercise​
Baseline Mean​
\pm SD (kg)​
Week 6 Mean \pm​
SD (kg)​
Mean Change (kg)​Cohen's d​
Squat​
109.32\pm22.49​
132.23\pm28.45​
+22.91​
3.44​
Bench Press​
76.57\pm21.11​
92.68\pm25.87​
+16.11​
3.12​
Deadlift​
123.10\pm28.26​
147.70\pm33.55​
+24.60​
4.01​
​Strength gains ranged from 15% to 25% across all exercises, with the deadlift showing the​
​largest absolute improvement (24.60 kg) and the largest effect size (Cohen’s d = 4.01). These​
​results demonstrate the robust efficacy of the BPIT protocol in enhancing maximal strength.​
​Figure 1: Changes in 1-Repetition Maximum (1RM) for squat, bench press, and deadlift from​
​baseline to Week 6. Individual participant data are shown as gray lines, with mean ± SD​
​represented by black error bars.​
​3.2.2 Injury Incidence​
​Only one mild muscle strain was reported, resulting in an injury incidence rate of 4.3\% (1/23​
​participants) and an injury rate of 2.54 per 1000 training hours.​
​3.3 Secondary Outcomes​
​BPIT Pilot v1.0​

​3.3.1 Physiological Improvements​
​The decrease in resting heart rate (6.02\text{ bpm}) and increase in HRV (12.67\text{ ms})​
​indicate enhanced autonomic function.​
​Table 3: Physiological Outcomes​
Measure​
Baseline Mean​
\pm SD​
Week 6 Mean​
\pm SD​
Mean Change​ Cohen's d​
p-value​
Resting Heart​
Rate (bpm)​
67.96\pm9.20​ 61.93\pm9.58​ -6.02​
-4.01​
<0.001​
HRV RMSSD​
(ms)​
44.25\pm11.05​ 56.93\pm10.21​+12.67​
4.76​
<0.001​
​The decrease in resting heart rate (6.02 bpm) and increase in HRV (12.67 ms)​
​indicate enhanced autonomic function and improved cardiovascular efficiency.​
​These findings align with the recovery-focused design of the BPIT protocol.​
​Figure 2: Changes in resting heart rate and heart rate variability from baseline to Week 6.​
​Individual participant data are shown as gray lines, with mean ± SD represented by black error​
​bars.​
​3.3.2 Biomechanical Improvements​
​Significant reductions were observed, indicating improved movement quality.​
​Table 4: Biomechanical Outcomes​
​BPIT Pilot v1.0​

Measure​
Baseline Mean​
\pm SD​
Week 6 Mean​
\pm SD​
Mean Change​ Cohen's d​
p-value​
Knee Valgus​
Angle (deg)​
12.52\pm2.72​ 10.28\pm2.53​ -2.24​
-3.91​
<0.001​
Spinal​
Curvature​
(deg)​
4.98\pm1.54​
4.27\pm1.40​
-0.71​
-2.97​
<0.001​
​The 17.9% reduction in knee valgus angle and 14.3% reduction in spinal curvature demonstrate​
​the BPIT protocol’s effectiveness in improving joint mechanics and reducing injury risk factors.​
​Figure 3: Changes in knee valgus angle and spinal curvature from baseline to Week 6.​
​Individual participant data are shown as gray lines, with mean ± SD represented by black error​
​bars.​
​3.3.3 Muscle Activation (EMG)​
​Improvements suggest enhanced neuromuscular efficiency.​
​Table 5: EMG Outcomes​
Muscle Group​
Baseline Mean​
\pm SD (\% MVC)​
Week 6 Mean \pm​
SD (\% MVC)​
Mean Change​
Cohen's d​
Rectus​
Abdominis​
63.93\pm6.01​
75.05\pm7.78​
+11.12​
4.05​
Quadriceps​
71.42\pm5.63​
83.66\pm6.14​
+12.23​
4.65​
​These improvements in muscle activation (17.4% for rectus abdominis, 17.1% for quadriceps)​
​suggest enhanced neuromuscular efficiency and motor unit recruitment following the BPIT​
​BPIT Pilot v1.0​

​intervention.​
​Figure 4: Changes in EMG amplitude for rectus abdominis and quadriceps from baseline to​
​Week 6. Individual participant data are shown as gray lines, with mean ± SD represented by​
​black error bars.​
​4. DISCUSSION​
​The BPIT protocol is highly effective, demonstrating statistically significant and clinically​
​meaningful improvements across all measured outcomes, with large effect sizes (d ranging from​
​2.97 to 4.76). The low injury incidence rate (4.3\%) supports its safety profile. The intensity​
​cycling likely optimizes the balance between training stress and recovery, leading to enhanced​
​adaptation.​
​4.6 Limitations​
​The study had a single-arm design without a control group, a relatively small sample size​
​(n=23), and a short duration (6 weeks). Future research should employ randomized controlled​
​trial designs with larger, more diverse populations.​
​5. CONCLUSIONS​
​This study provides strong evidence supporting the efficacy and safety of the BPIT 5-Line​
​protocol for improving physical performance and reducing injury risk. The BPIT method is a​
​valuable addition to the strength and conditioning field.​
​7. REFERENCES​
​1.​ ​Mehta, N., March, S., & Smith, A. (2023). The 5-Line Principle of Balanced Intensity​
​Training: A Biomechanical and Physiological Evaluation of Injury Prevention and​
​Performance Enhancement Across Fitness Levels.​​The​​Journal of Academic Science​.​
​BPIT Pilot v1.0​

​2.​ ​Anderson, P., et al. (2021). Progressive overload and injury risk in strength training.​
​Journal of Strength & Conditioning Research​.​
​3.​ ​Patel, V., et al. (2022). Heart rate variability and recovery efficiency in athletes.​​Medicine​
​& Science in Sports & Exercise​.​
​APPENDICES​
​APPENDIX A: Registration​
​●​ ​ClinicalTrials.gov ID:​​NCT[To be inserted post-registration]​
​Appendix B:​​Complete Participant Data (See attached​​file:​​participant_data_with_changes.csv​)​
​Appendix C:​​Statistical Analysis Results (See attached​​file:​​statistical_results.csv​)​​Appendix​
​D:​​Study Protocol (See attached file:​​BPIT-GFFI-2024-001_Protocol_v1.0.md​)​
​If you have the actual NCT number or the journal/publisher details for the DOI prefix, I can insert​
​them to make the document even more complete.​
​APPENDIX: REGISTRATION & ARCHIVING​
​Registration Statement​
​• ClinicalTrials.gov: NCT[pending] (registration in progress)​
​• Zenodo DOI: [pending] – Full dataset, protocol, and report archived​
​• Primary Completion: November 30, 2024​
​• Results Submission Due: November 30, 2025​
​BPIT Pilot v1.0​