Procjena Postoperativne Boli Konvencionalnom i Tumescentnom Anestezijom u Laserskom Tretmanu Pilonidalnog Sinusa
Phase: NA
Conditions: Pilonidal Cyst and Sinus Without Abscess, Pilonidal Sinus Disease, Pilonidal Sinus Treatment, Laser Ablation
Sponsor: Opća županijska bolnica Požega

O"icial Title: 
Tumescent Local Anesthesia versus Conventional Local Anesthesia for Sinus Laser 
Closure (SiLaC) 
NCT Number: 
NCT ID not yet assigned  
Document: 
Study Protocol 
Document Date: 
24 January 2026  
Institution: 
Opća Županijska Bolnica Požega - General County Hospital Požega 
Principal Investigator: 
Gabriela Katharina Pomper, MD, PhD 
Study Type: 
Prospective, randomized, single-center interventional study  
Study Period: 
01 September 2025 – 31 August 2027  
 
 
 
 
 
 
Study Protocol  
 
Background:  
Pilonidal disease aSects approximately 2% of the population and signiﬁcantly reduces 
quality of life. Local anesthesia has been shown to reduce postoperative pain and 
hospital stay. Tumescent local anesthesia may further improve outcomes, but evidence 
in laser treatment of pilonidal sinus is lacking.  
Objective:  

To compare postoperative pain between conventional and tumescent local anesthesia 
in laser treatment of pilonidal sinus.  
Hypothesis:  
There is a statistically signiﬁcant diSerence (p < 0.05) in VAS pain scores between the 
two anesthesia techniques.  
Methods:  
Approximately 100 adult patients undergoing laser treatment for pilonidal sinus will be 
enrolled. Participants will be randomized using sealed envelopes. Pain will be assessed 
using the VAS scale preoperatively and on postoperative days 1, 2, and 7.  
Inclusion Criteria: 
- Adults ≥18 years 
- Diagnosed pilonidal sinus disease 
- Laser treatment for pilonidal sinus disease - Able to provide informed consent  
Exclusion Criteria: 
- Minors 
- Recurrent pilonidal sinus - Chronic pain syndrome 
- Prisoners  
Ethics:  
Participation is voluntary. Written informed consent will be obtained. Data will be 
collected anonymously.  
Expected Outcome:  
Identiﬁcation of an anesthesia technique associated with less postoperative pain and 
improved patient satisfaction.