Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)
Phase: NA
Conditions: Physical Fitness
Sponsor: MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

​🩺 BPIT Clinical Study Protocol (Version​
​3.3): Document1​
​Date: 2025-12-08​
​Balanced Progressive Intensity Training (BPIT): Multi-Site Clinical Study on Movement​
​Efficiency, Mobility, and Strength Adaptation​
​DOI:​​10.5281/zenodo.17594478​
​ClinicalTrials.gov ID​​NCT07256717​
​IMSO:​​IMSO-REG-20251125-PM-1458-TA​​G​​.​
​Institutional Header​
​MMSx Authority Institute for Movement Mechanics & Biomechanics Research​
​In Collaboration with BodyGNTX Institute | GFFI India | IIKBS | Bureau of Fitness Standards​
​(BFS) | Active India Health & Fitness Trust (AIHFT)​
Field​
Detail​
Study Title​
Balanced Progressive Intensity Training (BPIT):​
A Five-Week Multi-Site Clinical Evaluation of​
Functional Movement, Mobility, and​
Neuromuscular Adaptation in Healthy Adults​
(18-65 years)​
Principal Investigator​
Dr. Neeraj Mehta, Ph.D. (Biomechanics &​
Alternative Medicine), Clinical Biomechanics &​
Research Ethics Certified (OHRP–HHS USA |​
ICMR India)​
Collaborating Institutes​
MMSx Authority Institute | BodyGNTX | GFFI​
India | IIKBS | BFS | AIHFT​
Study Type​
Prospective, observational intervention study​
Study Duration​
5 Weeks​
Study Sites​
BFS- and AIHFT-approved training &​
rehabilitation centers​
IMSO Accreditation ID​
[Insert IMSO Accreditation ID]​
​BPIT Multi-Site Clinical Study v3.3 (2025-2026) | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. | Confidential – For Authorized Use Only​

​Version History Section​
​Version History:​
​- Version 3.0: Original draft, July 2025 (anticipated).​
​- Version 3.1: Minor updates for multi-site details, November 6, 2025.​
​- Version 3.2: Reviewed for ClinicalTrials.gov submission on November 25, 2025; no substantive​
​changes to study design or methods.​
​- Version 3.3: Reviewed for ClinicalTrials.gov submission on​​2025-12-08​; no substantive​
​changes to study design or methods.​
​2. About the BPIT Method (Revised)​
​Balanced Progressive Intensity Training (BPIT) is a biomechanical and physiological​
​strength-training framework created by Dr. Neeraj Mehta. Its primary goal is to harmonize​
​intensity progression, internal load distribution, and neuromuscular efficiency, thereby resolving​
​the traditional training-injury paradox.​
​2.1. The BPIT 5-Line Principle​
​BPIT organizes all strength and movement exercises into five distinct intensity lines. Each line is​
​defined by specific physical parameters, enabling a safe and structured progression from​
​stability to power without generating overuse stress.​
Line​
Movement Base​
Target HR (bpm)​
Focus & Purpose​ Examples​
1 –​
Ground-Based​
Floor / Low GRF​
95-110​
Core activation +​
breath stability​
Plank, Crunch,​
Dead Bug​
2 – Knee-Level​
Supported /​
Moderate GRF​
100-120​
Joint centration &​
controlled press /​
pull​
Bench Press,​
Seated Row​
3 – Standing​
Full Bodyweight​
120-140​
Alignment &​
Kinetic-integration​
chain​
Squat, Deadlift​
4 – Head-Level​
Overhead /​
Elevated​
140-160​
Thoracic mobility &​
scapular control​
Overhead Press,​
Lunge​
5 – Plyometric​
Dynamic Impact​
160-180​
Elastic power &​
Jump Squat,​
​BPIT Multi-Site Clinical Study v3.3 (2025-2026) | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. | Confidential – For Authorized Use Only​

Line​
Movement Base​
Target HR (bpm)​
Focus & Purpose​ Examples​
injury resilience​
Burpee, Box Jump​
​2.2. Biomechanical Framework​
​The BPIT methodology operates by balancing​​mechanical​​stimulus \times biomechanical​
​integrity \approx physiological recovery​, ensuring​​consistent adaptation. Key biomechanical​
​control mechanisms include:​
​●​ ​Ground Reaction Force (GRF) management​
​●​ ​Joint-Load Distribution analysis​
​●​ ​Heart-Rate (HR) and Heart Rate Variability (HRV) Control​
​3. Study Objectives​
​1.​ ​Evaluate the effect of BPIT on movement efficiency, mobility, and load control.​
​2.​ ​Quantify biomechanical and neuromuscular changes across the 5-week period.​
​3.​ ​Observe individual variance in adaptation and note any mobility or postural deviations.​
​4.​ ​Identify early-stage indicators of overload to refine safety parameters.​
​4. Methodology​
​4.1. Design and Participants​
​●​ ​Design:​​Multi-site, prospective, real-world clinical​​observation.​
​●​ ​Participants:​​\geq 369 healthy adults (18-65 years).​
​●​ ​Inclusion Criteria:​​No acute injury / medically cleared​​for exercise.​
​●​ ​Exclusion Criteria:​​Chronic pathology, cardiac instability,​​recent surgery.​
​●​ ​Sample size:​​n=100 for 80% power (α=0.05, effect size=0.5​​via G*Power 3.1), detecting​
​moderate changes in MES/ROM with 10% dropout.​
​●​ ​Control group:​​Standard progressive overload training​​(no BPIT lines) for comparison.​
​●​ ​Additional exclusions:​​BMI >35, pregnancy, uncontrolled​​hypertension, or recent​
​surgery (<6 months).​
​4.2. Procedure: 5-Week Progression​
​BPIT Multi-Site Clinical Study v3.3 (2025-2026) | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. | Confidential – For Authorized Use Only​

Week​
Phase​
Focus​
Assessment Tool​ Expected​
Outcome​
0​
Baseline​
Screening​
Posture & Mobility​ MMSx Flaw​
Checklist + BPIT​
Line Mapping​
Establish​
Reference​
1-2​
Correction Phase​ Stability & Joint​
Centration​
Controlled​
Low-Load BPIT​
\downarrow​
Compensation​
Patterns​
3-4​
Progressive Phase​Load Adaptation &​
Efficiency​
Mid-Load BPIT​
\uparrow MES &​
ROM​
5​
Evaluation Phase​ Power Integration​ Final BPIT Test +​
Clinical ROM​
\uparrow Strength​
& Control​
​5. Data Collection Parameters​
​All data will be stored in the​​BodyGNTX Research Registry​​with anonymized codes.​
Variable​
Metric/Tool​
Evaluator​
Frequency​
Movement Efficiency​
Score (MES)​
BPIT Observation​
Scale 0-10​
MMSx Expert​
Weekly​
Range of Motion​
(ROM)​
Goniometer / Digital​
App​
Assessor​
Wk 0, 3, 5​
Pain Scale (VAS 0-10)​ Self-Report​
Site Clinician​
Weekly​
Strength Index​
Rep x Load Chart​
Trainer​
Wk 0, 5​
Postural Symmetry​
Video Analysis​
Research Staff​
Wk 0, 5​
​6. Ethical & Medical Oversight​
​●​ ​Study conducted per Declaration of Helsinki (2013) and WHO GCP guidelines.​
​●​ ​Participants must sign the official MMSx Informed Consent Form before initiation.​
​●​ ​Any participant showing adverse change in mobility, movement, or health status will be​
​referred to a medical specialist.​
​●​ ​Oversight is provided by registered orthopedic and sports-medicine doctors under the​
​MMSx Clinical Board​.​
​7. Expected Outcomes (Prognosis)​
​BPIT Multi-Site Clinical Study v3.3 (2025-2026) | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. | Confidential – For Authorized Use Only​

​BPIT is projected to validate the model as a safe and scientifically structured progression.​
​●​ ​Movement Efficiency Score improvement by \geq 25\%.​
​●​ ​ROM in major joints improvement by 15-20\%.​
​●​ ​Strength Index improvement by 20-30\%.​
​●​ ​Injury risk reduction by \geq 35\%.​
​8. Signatures​
Role​
Name / Institution​
Signature​
Date​
Principal Investigator​ Dr. Neeraj Mehta -​
MMSx Authority​
2025-12-08​
Site Expert / Clinician​[Name / Institution]​
Medical Observer /​
Orthopedist​
[Name / Institution]​
IRB / Ethics Approval​ [MACREB Chair Name]​
​©2025 MMSx Authority Institute for Movement Mechanics & Biomechanics Research​
​Mehta, N., March. S, . Smith J., & Malhotra, S. (2025). Balanced Progressive Intensity Training​
​(BPIT): A Multi-Site Clinical Evaluation of Movement Efficiency, Mobility, and Strength​
​Adaptation (v3.3) (v3.3) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.17594478​
​BPIT Multi-Site Clinical Study v3.3 (2025-2026) | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. | Confidential – For Authorized Use Only​