Response of the Cardiac Autonomic Control System After Oxygen Therapy 100% in Hyperbaric Environment
Conditions: Neurological Injury
Sponsor: Assaf-Harofeh Medical Center

Response of the cardiac autonomic control system after oxygen therapy 100% in 
hyperbaric therapy. 
Research Objectives 
 •Evaluation of the function of the autonomic control system for heart rate  variability in 
different subjects after being in a hyperbolic environment.  
 •Examining the reflective response of the autonomic control system to stimuli at different 
stages of treatment. 
 •Examining the response of the autonomic system to physical, cognitive action at different 
stages of treatment. 
Research Process: 
After signing the Informed Consent Form, the study participants will be examined at four 
time periods: two weeks prior to starting treatment, one month after starting treatment, 
last week for the treatment series (if the treatment continues for more than 6 weeks / 30 
weeks) and one month after treatment ends. Each time the subject is connected to a Polar 
watch  and a breath strip. A test of about half an hour will be conducted during which the 
subjects will be asked to perform: 
• 
Grip Test - Handshake Test 
• 
Breathing Test - Breathing test in which the subject is required to take 6 breaths per 
minute. 
• 
Cognitive sitting task - subtracting serial number 3 from a random number in the 100 s). 
The subject was given a three-digit number and for a whole minute he had to miss each 
time by jumping three. 
• 
Motor task - standing from sitting to standing. 
• 
Performing a motor task + a cognitive task 
A 5 minute rest will be given between the various tests. 
The tests are non-invasive and do not pose any risk to the patient.