Health Care Resource Utilization, Cost and Other Outcomes of Patients Diagnosed With COPD Initiating Tiotropium Bromide/Olodaterol Versus Fluticasone Furoate/Umeclidinium/Vilanterol
Conditions: Pulmonary Disease, Chronic Obstructive
Sponsor: Boehringer Ingelheim

ABCD
001-MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
TITLE PAGE
Non-Interventional Study (NIS) Protocol
TITLE PAGE
Document Number:
c37262534-01
BI Study Number:
   1237-0113
BI Investigational
Product(s):
Stiolto Respimat (Tiotropium Bromide/Olodaterol)
Title:
Health Care Resource Utilization, Cost and Other Outcomes of 
Patients Diagnosed with COPD Initiating Tiotropium 
Bromide/Olodaterol versus Fluticasone 
Furoate/Umeclidinium/Vilanterol
Brief lay title:
Outcomes among COPD patients initiating TIO/OLO vs 
FF/UMEC/VI
Protocol version 
identifier:
Version 1.0
Date of last version of 
protocol:
04 May 2021
PASS:
No
EU PAS register 
number:
Study not registered
Active substance:
Tiotropium Bromide/Olodaterol
Medicinal product:
Stiolto Respimat (Tiotropium Bromide/Olodaterol)
Product reference:
NA
Procedure number:
NA
Marketing 
authorisation holder(s):
Boehringer Ingelheim
Joint PASS:
NA
Research question and 
objectives:
The purpose of this study is to estimate disease-related and all-cause
burden and clinical outcomes of interest following initiation of COPD 
maintenance therapy with TIO/OLO or FF/UMEC/VI.

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Country(-ies) of study:
United States
Author:
Boehringer Ingelheim: 
Marketing 
authorisation holder(s):
NA
In case of PASS, add:
MAH contact person:
NA
In case of PASS, add:
<EU-QPPV:>
NA
In case of PASS, add:
<Signature of EU-
QPPV:>
NA
Date:
04 May 2021
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© 2022 Boehringer Ingelheim Group of companies. All rights reserved.
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1.
TABLE OF CONTENTS
TITLE PAGE ........................................................................................................................1
1.
TABLE OF CONTENTS...............................................................................................3
2.
LIST OF ABBREVIATIONS........................................................................................5
3.
RESPONSIBLE PARTIES............................................................................................6
4.
ABSTRACT...................................................................................................................7
5.
AMENDMENTS AND UPDATES.............................................................................11
6.
MILESTONES.............................................................................................................12
7.
RATIONALE AND BACKGROUND........................................................................13
8.
RESEARCH QUESTION AND OBJECTIVES .........................................................15
9.
RESEARCH METHODS ............................................................................................16
STUDY DESIGN..........................................................................................16
SETTING ......................................................................................................17
9.2.1
Observation period ........................................................................................17
9.2.2
Observation period – secondary objective ....................................................19
9.2.3
Study sites......................................................................................................19
9.2.4
Study population............................................................................................19
9.2.4.1 Patient Identification – Eosinophil Subgroup..................................................20
9.2.5
Study visits ....................................................................................................21
9.2.6
Study discontinuation....................................................................................21
VARIABLES.................................................................................................21
9.3.1
Exposures ......................................................................................................21
9.3.2
Outcomes.......................................................................................................21
9.3.2.1 Primary outcomes ............................................................................................21
9.3.2.2 Secondary outcomes ........................................................................................25
9.3.3
Covariates......................................................................................................26
9.3.3.1 Clinical Characteristics....................................................................................26
9.3.3.2 Patient Characteristics......................................................................................29
DATA SOURCES.........................................................................................30
9.4.1
Database.............................................................................30
9.4.2
Laboratory Results ........................................................................................31
STUDY SIZE ................................................................................................31

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DATA MANAGEMENT..............................................................................31
DATA ANALYSIS .......................................................................................32
9.7.1
Comparison of TIO/OLO Initiators...............................................................32
9.7.2
Main analysis.................................................................................................32
9.7.3
Primary Objectives........................................................................................33
9.7.3.1 Descriptive Analysis........................................................................................33
9.7.3.2 Kaplan Meier Analysis ....................................................................................34
9.7.3.3 Number Needed to Treat..................................................................................34
9.7.3.4 Multivariable Analysis (Optional)...................................................................34
9.7.4
Secondary Objective......................................................................................35
9.7.4.1 COPD Readmission CMS Definition ..............................................................35
LIMITATIONS OF THE RESEARCH METHODS....................................36
OTHER ASPECTS........................................................................................37
9.9.1
Data quality assurance...................................................................................37
9.9.2
Study records.................................................................................................37
9.9.2.1 Source documents............................................................................................37
10.
PROTECTION OF HUMAN SUBJECTS....................................................38
STUDY APPROVAL, PATIENT INFORMATION, AND INFORMED 
CONSENT
.......................................................................................................................38
STATEMENT OF CONFIDENTIALITY....................................................38
11.
MANAGEMENT AND REPORTING OF ADVERSE EVENTS/ADVERSE 
REACTIONS ......................................................................................................................39
ADVERSE EVENT AND SERIOUS ADVERSE EVENT COLLECTION 
AND REPORTING .............................................................................................................39
12.
PLANS FOR DISSEMINATING AND COMMUNICATING STUDY 
RESULTS
.......................................................................................................................40
13.
REFERENCES..............................................................................................41
PUBLISHED REFERENCES.......................................................................41
ANNEX 1. LIST OF STAND-ALONE DOCUMENTS ....................................................43
ANNEX 2. ENCEPP CHECKLIST FOR STUDY PROTOCOLS ....................................44
ANNEX 3. ADDITIONAL INFORMATION....................................................................45
ANNEX 4. REVIEWERS AND APPROVAL SIGNATURES .......................................252

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2.
LIST OF ABBREVIATIONS
CI
Confidence Intervals
CMS
Centers for Medicare and Medicaid Services
COPD
Chronic Obstructive Pulmonary Disease
CPI
Consumer Price Index
CPT
Current Procedural Terminology
ED
Emergency Department
EPO
Exclusive Provider Organization
ER
Emergency Room
FDA
Food and Drug Administration
FDC
Fixed Dose Combination 
GOLD
Global Initiative for Chronic Obstructive Lung Disease
HCFA
Health Care Financing Administration
HCPCS
Healthcare Common Procedure Coding
HCRU
Health Care Resource Utilization
HIPAA
Health Insurance Portability and Accountability Act
HMO
Health Maintenance Organization
HPSA
Health Professional Shortage Areas
ICD
International Statistical Classification of Diseases and Related Health 
Problems
ICS
Inhaled Corticosteroid
IMPACT
InforMing the Pathway of COPD Treatment
KM
Kaplan-Meier
LABA
Long-acting ß-agonist
LAMA
Long-acting Antimuscarinic
MAPD
Medicare Advantage Part D
NNT
Number Needed to Treat
OCS
Oral Corticosteroid
D
 Database
POS
Point of Service
PPO
Preferred Provider Organization
PSM
Propensity Score Matching
SABA
Short-acting ß-agonist
SAMA
Short-acting Anticholinergics
TIO/OLO
Tiotropium/Olodaterol
TT
Triple Therapy
UB
Uniform Billing
UMEC
Umeclidinium
US
United States
VI
Vilanterol

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3.
RESPONSIBLE PARTIES

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4.
ABSTRACT
Name of company:
Boehringer Ingelheim
Name of finished medicinal 
product:
Stiolto Respimat
Name of active ingredient:
Tiotropium Bromide/Olodaterol
Protocol date:
Study
number:
Version/Revision:
Version/Revision date:
04 May 2021
1237-0113
1.0
NA
Title of study:
Health Care Resource Utilization, Cost and Other Outcomes of Patients 
Diagnosed with COPD Initiating Tiotropium Bromide/Olodaterol versus 
Fluticasone Furoate/Umeclidinium/Vilanterol
Rationale and 
background:
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 
report recommends dual therapy with long-acting muscarinic antagonists 
(LAMAs) plus long-acting beta2 agonists (LABAs) for patients with chronic 
obstructive pulmonary disease (COPD) who have persistent symptoms and/or 
exacerbations on LAMA or LABA monotherapy. Consideration of escalation 
to triple therapy (TT; LAMA+LABA+inhaled corticosteroids [ICS]) is 
recommended in case of further exacerbation and after assessing the 
risks/benefits, including the increased risk of pneumonia with ICS treatment. 
A blood eosinophil count >300 cells/µL and exacerbation history together 
can be used to identify patients with the greatest likelihood of treatment 
benefit with ICS. Despite these recommendations, evidence suggests TT is 
over-prescribed across all COPD severities, including those at low 
exacerbation risk. This deviation from GOLD recommendations may have 
economic and clinical consequences.
Data from multiple Phase III randomized clinical trials comparing FDC TT 
and LAMA/LABA are currently available. However, for the purposes of this 
study only one trial - InforMing the PAthway of COPD Treatment (IMPACT) 
- compared FDC fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI; 
Trelegy Ellipta) and LAMA/LABA (specifically umeclidinium/vilanterol 
[UMEC/VI; Anoro Ellipta]). The study found significantly lower 
exacerbation rates, higher pneumonia rates [R18-1532], and reduction in all-
cause mortality risk [R21-4089] for FF/UMEC/VI.
We aim to understand the clinical and economic implications of prescribing 
FDC TT vs. TIO/OLO in clinical practice.
Research question 
and objectives:
The purpose of this study is to estimate disease-related and all-cause burden 
and clinical outcomes of interest following initiation of COPD maintenance 
therapy with TIO/OLO or FF/UMEC/VI.

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Study design:
This will be a retrospective study of commercial and MAPD beneficiaries, 
using administrative claims data for the period of 01 January 2013 through 
31 December 2019. This study will include patients diagnosed with COPD 
who initiated treatment with TIO/OLO or FF/UMEC/VI between 01 June
2015 and 30 November 2019. Patients will be assigned to one of the 
following mutually exclusive study cohorts based on the index pharmacy 
claim: TIO/OLO or FF/UMEC/VI. Stratified propensity score matching 
(PSM), using an exact match on some variables and a propensity score 
match on the others, will be used to control for possible confounding of the 
association between the outcomes (e.g., health care resource utilization) and 
treatment with TIO/OLO or FF/UMEC/VI.
Population:
Inclusion Criteria

≥30 consecutive days with TIO/OLO or FF/UMEC/VI initiated during 
the patient identification period of 01 June 2015 to 30 November 2019. 
The index date will be the date of the TIO/OLO or FF/UMEC/VI 
pharmacy claim that starts the ≥30 consecutive days with the 
medication.   

≥1 facility claim with a diagnosis of COPD in the primary position or 
≥2 professional claims with a diagnosis code for COPD (Annex 3) in 
any position on separate dates of service during the study period

≥40 years of age as of the year of the index date

Continuous enrollment with medical and pharmacy coverage for 12 
months prior to and including the index date (baseline period)

Continuous enrollment with medical and pharmacy coverage for ≥30 
days following the index date and without discontinuation of the index 
medication or switch to a non-index regimen (follow-up period); 
discontinuation and switch are defined in Section 9.2.1.
Exclusion Criteria

≥2 medical claims with a diagnosis code for asthma, cystic fibrosis, 
lung cancer, or interstitial lung disease (Annex 3) in any position on 
separate dates of service during the baseline period 

Pharmacy claims for both TIO/OLO and FF/UMEC/VI on the index 
date

A pharmacy claim for any non-index COPD maintenance medication 
on the index date, defined as: LAMA monotherapy; LABA 
monotherapy; ICS monotherapy; FDC ICS/LABA, or FDC 
LAMA/LABA (Annex 3)

Free or fixed dose LAMA+LABA maintenance therapy defined as ≥7 
consecutive days of overlapping days’ supply with a LAMA and 
LABA during a 6-month pre-index period, excluding the index date 
(Annex 3) 

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
Flags will be created to identify patients excluded for baseline 
LAMA/LABA use overall and specifically for each FDC 
LAMA/LABA medication

Free or fixed dose TT defined as ≥7 consecutive days of overlapping 
days’ supply with an ICS, LABA, and LAMA during a 6-month pre-
index period, excluding the index date (Annex 3) 

≥1 medical claim with a procedure code for lung volume reduction 
during the study period (Annex 3)

Unknown age, gender, or business line, or unknown/other geographic 
region
The exclusion criteria for previous medication use was relaxed to ≥7 
consecutive days of overlapping days’ supply rather than ≥1 day of 
overlapping days’ supply based on the number of patients excluded in the 
attrition table. This decision was made after reviewing the attrition tables 
using the two criteria and before any baseline or follow-up analyses were 
completed. 
Study inclusion and exclusion criteria will be finalized during review of the 
patient attrition table, and prior to any baseline or follow-up analyses. 
Variables:
Exposures
Patients will be assigned to one of the following mutually exclusive study 
cohorts based on the index pharmacy claim: TIO/OLO or FF/UMEC/VI.
Outcomes
COPD and/or pneumonia-related costs and HRU
COPD-related costs and HRU
Pneumonia-related costs and HRU
All-cause costs and HRU
COPD or pneumonia-attributable costs and HRU
COPD exacerbations
Pneumonia diagnoses
Pneumonia-related hospitalization
COPD exacerbation and/or pneumonia diagnosis 
Baseline characteristics
Clinical and demographic characteristics
HRU
Costs
Data sources:
The 
 Database (
D), is fully de-identified and HIPAA 
compliant, and comprised of medical and pharmacy claims data (including 
linked enrollment information) from 1993 to present on more than 73 
million lives.
Study size:
Using claims data for commercial and Medicare Advantage health plan 
enrollees we identified 5,717 and 17,733 patients who initiated treatment 

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with TIO/OLO or FF/UMEC/VI, respectively, between 01 January 2018 
and 31 July 2019. These patients had 12-months of baseline and ≥30 days of 
follow-up continuous enrollment with both medical and pharmacy coverage. 
This count is for informational purposes only and may not represent the 
actual number of patients to be utilized in the study. Application of other 
inclusion and exclusion criteria required for this study or other factors may 
reduce the sample size.
Data analysis:
Baseline categorical variables will be presented as numbers and percentages 
and baseline continuous variables will be presented as means, standard 
deviations, medians, and interquartile ranges. Follow-up variables will be 
presented as population annualized averages to account for the variable 
follow-up duration (minimum 1 month, maximum 12 months). Population 
annualized averages will be calculated as ([sum of all utilization or cost for 
all individuals during the follow-up period]/[sum of all follow-up time in 
days for all individuals])*365. Wald 95% confidence intervals (CI) will be 
provided for annualized population averages using the Taylor expansion to 
estimate the standard error. The numerator and denominator of the 
population annualized average equation and the 95% CI will be presented.
Appropriate tests comparing the TIO/OLO cohort and the FF/UMEC/VI 
cohort (e.g., standardized differences, McNemar’s tests, paired t-tests, sign 
tests) will be used based on the distribution of the measure.
Milestones:
Final report planned: March 2022

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5.
AMENDMENTS AND UPDATES
None

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6.
MILESTONES
Milestone
Planned Date
Final report of study results:
March 2022

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7.
RATIONALE AND BACKGROUND
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2020 report 
recommends dual therapy with long-acting muscarinic antagonists (LAMAs) plus long-acting 
beta2 agonists (LABAs) for patients with chronic obstructive pulmonary disease (COPD) who 
have persistent symptoms and/or exacerbations on LAMA or LABA monotherapy. 
Consideration of escalation to triple therapy (TT; LAMA+LABA+inhaled corticosteroids 
[ICS]) is recommended in case of further exacerbation and after assessing the risks/benefits, 
including the increased risk of pneumonia with ICS treatment. A blood eosinophil count 
>300 cells/µL and exacerbation history together can be used to identify patients with the 
greatest likelihood of treatment benefit with ICS. Despite these recommendations, evidence 
suggests TT is over-prescribed across all COPD severities, including those at low 
exacerbation risk. This deviation from GOLD recommendations may have economic and 
clinical consequences.
A recently completed retrospective observational claims analysis of COPD patients enrolled 
in a Medicare-Advantage with Part D (MAPD) coverage plan, compared on-treatment COPD 
related healthcare cost and resource utilization (HCRU) among patients initiating 
tiotropium/olodaterol (TIO/OLO) vs. TT. Findings using propensity score matched cohorts 
included 41% ($7,041) lower annualized cost per patient for TIO/OLO vs. TT ($10,094 vs. 
$17,135, P<.001) [P20-06571]. 
A post-hoc analysis of the same population examined outcomes for TIO/OLO and TT cohorts 
by stratifying on maintenance naïve status (no baseline COPD maintenance medications) and 
baseline exacerbation history (0 exacerbations, 1 moderate and no severe exacerbations, and 
≥2 moderate or ≥1 severe exacerbations) and then matching on patient characteristics. Across 
these various subgroups, post-propensity score match, COPD-related annual costs for 
TIO/OLO versus TT were found to be significantly lower, with the greatest differences 
among the maintenance naïve and no exacerbation history subgroups, with 47% ($8,018) and 
53% ($8,478) lower annual costs per patient, respectively. Cost differences in both subgroups 
were driven by COPD-related medical costs with 57% and 60% contribution, respectively, 
towards the observed total difference. Composite COPD/pneumonia related costs for 
TIO/OLO were similarly lower in the maintenance naïve (47% [$9,548]) and no exacerbation 
history subgroups (56% [$10,274]) compared to TT.
The same analysis also examined exacerbation and pneumonia diagnosis outcomes. After 
adjusting for treatment and additional covariates, the risk for a severe exacerbation was 
approximately 57% lower, for TIO/OLO patients with no exacerbation history compared to 
TT patients (P=0.002). The risk for pneumonia or acute bronchitis/bronchiolitis was 
approximately 34% lower among the TIO/OLO cohort with no exacerbation history 
compared to the TT cohort (P=0.018). However, the generalizability of these findings to 
contemporary TT initiators is limited since the TT cohort was predominantly composed of 
free-dose TT combinations. Only 1% involved fixed-dose combination (FDC) TT owing to 
the study end date.  

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Data from multiple Phase III randomized clinical trials comparing FDC TT and 
LAMA/LABA are currently available. However, for the purposes of this study only one trial -
InforMing the PAthway of COPD Treatment (IMPACT) - compared FDC fluticasone 
furoate/umeclidinium/vilanterol (FF/UMEC/VI; Trelegy Ellipta) and LAMA/LABA 
(specifically umeclidinium/vilanterol [UMEC/VI; Anoro Ellipta]). The study found 
significantly lower exacerbation rates, higher pneumonia rates [R18-1532], and reduction in 
all-cause mortality risk [R21-4089] for FF/UMEC/VI. Additionally, a recently completed 
post-hoc, within trial economic analysis of this trial data found that FF/UMEC/VI resulted in 
lower 1-year on-treatment COPD exacerbation-related costs that were attributable to the 
lower exacerbation events for FDC TT rates from the trial [R21-4088] . However, both the 
trial and this post-hoc analysis have a few significant limitations in design and 
generalizability. Primarily, the trial itself involved a predominately severe COPD patient 
population of frequent exacerbators or GOLD C/D patients (70% were GOLD Group D and 
74% had at least 2 moderate and/or 1 severe exacerbation in the year preceding the trial) and 
is not representative of the general COPD population. And the post-hoc analysis was further 
limited since it did not account for costs of maintenance treatment and pneumonia events, 
which may have offset the cost savings observed for FF/UMEC/VI.
Following the approval of FF/UMEC/VI FDC TT in late 2017 for the long-term maintenance 
treatment of COPD, this study attempts to fill the existing real-world evidence gap by 
comparing TIO/OLO vs. FF/UMEC/VI. We aim to understand the clinical and economic 
implications of prescribing FDC TT vs. TIO/OLO in clinical practice.

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8.
RESEARCH QUESTION AND OBJECTIVES
The purpose of this study is to estimate disease-related and all-cause burden and clinical 
outcomes of interest following initiation of COPD maintenance therapy with TIO/OLO or 
FF/UMEC/VI.
The specific primary objectives for this project are:

To compare disease related and all-cause HCRU among patients newly treated with 
TIO/OLO compared with patients newly treated with FF/UMEC/VI 

To compare disease-related and all-cause medical and total (medical & pharmacy) 
health care costs among patients newly treated with TIO/OLO compared with patients 
newly treated with FF/UMEC/VI 

To compare pneumonia outcomes among patients newly treated with TIO/OLO 
compared with patients newly treated with FF/UMEC/VI 

To compare COPD exacerbations following initiation of TIO/OLO or FF/UMEC/VI
The specific secondary objective for this project is:

To compare 30-day all-cause hospital readmissions following initiation of TIO/OLO 
or FF/UMEC/VI 
The study objectives will be assessed within each of the following populations of TIO/OLO 
and FF/UMEC/VI initiators:

Overall population of initiators (i.e., initiators who meet study selection criteria)

Maintenance naïve (patients with no baseline maintenance medication [no free or 
fixed dose combination (FDC) LAMA, LABA, or ICS])

No exacerbation (patients with no baseline exacerbation)

No exacerbation or 1 exacerbation not leading to hospitalization (i.e., baseline GOLD 
A/B)

≥2 exacerbations not leading to hospitalization or ≥1 exacerbation leading to 
hospitalization [i.e., baseline GOLD C/D]) 
Additionally, HCRU, costs, COPD exacerbations, and pneumonia outcomes following 
initiation of TIO/OLO or FF/UMEC/VI will be assessed among subgroups of patients with 
≥1 eosinophil lab in the following groups:

Baseline blood eosinophil count ≤300 cells/µL 

Baseline blood eosinophil count >300 cells/µL 

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9.
RESEARCH METHODS
STUDY DESIGN
This will be a retrospective study of commercial and MAPD beneficiaries, using 
administrative claims data for the period of 01 January 2013 through 31 December 2019. Due 
to the COVID-19 pandemic, no data from 2020 will be included in this analysis. Medical
claims are approximately 95% complete (fully adjudicated) approximately four to six months 
following the date of service. Pharmacy claims are complete (fully adjudicated) in the 
database approximately six weeks following the date of service. Laboratory results are 
typically added to the database within three to six months of administration of the test.
This study will include commercial and MAPD health plan members diagnosed with COPD 
who initiated treatment with TIO/OLO or FF/UMEC/VI between 01 June 2015 and 30 
November 2019. The start of the patient identification period is based on the Food and Drug 
Administration (FDA) approval date of 21 May 2015 for use of TIO/OLO (i.e., Stiolto) for 
treatment of COPD, and may be moved later (e.g., 01 August 2015) based on uptake of 
TIO/OLO within the 
D.
Ideally the patient identification period would only include the time period when both 
TIO/OLO and FF/UMEC/VI were approved for treatment of COPD. However, FF/UMEC/VI 
was FDA-approved for the treatment of COPD on 18 September 2017, and starting patient 
identification in January 2018 (to allow for uptake of FF/UMEC/VI in the 
D), would 
substantially reduce the number of TIO/OLO patients identified the study. Since meaningful 
effect sizes for the study comparisons currently are unknown, and the primary analysis 
focuses on key subgroups of initiators (e.g., maintenance naïve), the patient identification 
period will begin at TIO/OLO approval. 
TIO/OLO initiators with index dates before and after the FF/UMEC/VI approval data will be 
compared on a list of a priori baseline characteristics. The analytic plan, including the 
threshold for deciding if the TIO/OLO initiators are similar before and after FF/UMEC/VI 
approval is outlined in Section 9.7.1
Stratified propensity score matching (PSM), using an exact match on some variables and a 
propensity score match on the others, will be used to control for possible confounding of the 
association between the outcomes (e.g., health care resource utilization) and treatment with 
TIO/OLO or FF/UMEC/VI. This methodology has been widely used in observational studies 
for causal inference ever since it was introduced by Rosenbaum and Rubin.4 Depending on 
pre-match cohort sizes, patients will be matched in a 1:1 or 1:2 ratio of TIO/OLO to 
FF/UMEC/VI. Patients not matched will be excluded from the post-match analysis. 
Covariates for the stratified match may include:

Baseline exacerbation (number of severe and number of moderate exacerbations; 
yes/no)

Bronchodilator naïve status (naïve to LAMA and LABA)

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Potential covariates for the logistic regression model include:

Index year, seasonality

Patient demographics: age, gender, geographic region

Baseline medication use: controller and rescue 

Baseline comorbidity burden (e.g., Quan-Charlson Comorbidity Score without 
COPD)  

Baseline healthcare utilization: all-cause, COPD-related, pneumonia-related 

Baseline healthcare costs: all-cause, COPD-related, pneumonia-related
The final list of variables to be included in the propensity score modeling will be determined 
following review of the pre-matching descriptive analysis of patient characteristics and other 
baseline measures. 
The success of the matching procedure will be evaluated by comparing the characteristics 
included in the propensity score model between cohorts using standardized differences and 
other measures. Modifications may be made to the propensity score modeling procedure to 
increase sample size or improve balance between the cohorts. A standardized difference of 
≤10% for a measure will be considered as an acceptable threshold for balance between the 
treatment cohorts.  
Statistical tests between cohorts will include variance adjustments for the clustering due to 
matching.
A separate stratified PSM will be conducted among the subgroup of TIO/OLO and 
FF/UMEC/VI patients with baseline eosinophil laboratory results. The methodology applied 
to the overall sample will be replicated for this subgroup analysis. If the numbers allow, 
patients in the subgroup analysis will be hard matched on baseline exacerbation history, 
baseline bronchodilator naïve status, and baseline eosinophil level (eosinophil >300 cells/μL 
or eosinophil ≤300 cells/μL) and propensity score matched on other baseline variables.
As an alternative approach, inverse probability of treatment weighting (IPTW) may be 
conducted in lieu of PSM.
SETTING
9.2.1
Observation period
Patients will be required to be continuously enrolled in the health plan for a minimum of 13 
months. A schematic of the observation period is presented in Figure 1

Baseline period: The 12 months prior to and including the index date (index date–
364 through index date) will be used to assess baseline patient and clinical 
characteristics. The index pharmacy claims will be excluded from the baseline period 
and included in the follow-up period. 

Follow-up period: The variable period starting on the day after the index date, with a 
minimum of 30-days duration (index date+1 through index date+30) up to a 

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maximum of 12 months duration (index date+1 through index date+365) will be used 
to assess HCRU, costs, exacerbation and pneumonia outcomes. Patients will be 
censored at the earliest of the following: discontinuation of the index medication, 
switch to a non-index regimen, disenrollment from the health plan, 12-months 
following the index date, or the end of the study period. 
Discontinuation will be defined as a gap in therapy of ≥60 days following the 
runout of days supply (discontinuation date = runout prior to the gap). Because 
the discontinuation status of patients whose runout of index medication occurs 
<60 days before the end of their observation time is unobservable, patients with 
<60 days of observation time following the runout of their last index prescription 
claim will be flagged as censored, and their observation period will end on the 
runout date. 
Switch will be defined as a pharmacy fill for ≥30 consecutive days of a non-index 
ICS-, LABA-, or LAMA-containing medication (switch date = first date of the 
new treatment regimen). 
The distribution of follow-up time will be compared between the study cohorts. If there is a 
difference of more than one month of follow-up time between the cohorts, one or more of the
following options may be utilized: for binary outcomes, a Kaplan-Meier analyses restricted to 
when both cohorts have follow-up time; for continuous outcomes, censoring the follow-up
period of the cohort with longer follow-up such that the analysis is restricted to when both 
cohorts have follow-up time; for each matched pair (TIO/OLO and FF/UMEC/VI), use the 
minimum of follow-up time for the pair; include follow-up time in the propensity score 
match; or an alternative approach.
Figure 1
Observation Period for HCRU and Cost, COPD Exacerbation, and 
Pneumonia Outcomes

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9.2.2
Observation period – secondary objective
A hospitalization-level analysis will be used to examine 30-day all-cause hospital 
readmission after a COPD-related hospitalization while on the index regimens of interest. To 
be included in the readmission analysis, patients must meet the study selection criteria 
outlined in Section 9.2.4. plus have ≥1 eligible COPD-related hospitalization in the follow-up 
period with at least 30 days of continuous enrollment after discharge, unless readmission and 
death occur within 30 days of hospital discharge. Among patients who meet the study 
selection criteria, 30-day all-cause readmission following a COPD-related hospitalization 
while on the index regimens will be performed. Patients may contribute zero, one, or more 
than one observation depending on the number of COPD-related inpatient visits observed 
during follow-up. Each COPD-related hospitalization will be required to have at least 30 days 
of enrollment after the discharge date to be included in the analysis, unless readmission and 
death occur within 30 days of hospital discharge. Hospitalization discharge dates that occur 
within 30 days of the study end date will not be included because the readmission status is 
unobservable.
9.2.3
Study sites
The 
 Database (
D), is fully de-identified and HIPAA compliant, and 
comprised of medical and pharmacy claims data (including linked enrollment information) 
from 1993 to present on more than 73 million lives. 
9.2.4
Study population
Patients will be assigned to one of the following mutually exclusive study cohorts based on 
the index pharmacy claim: TIO/OLO or FF/UMEC/VI. 
Inclusion Criteria

≥30 consecutive days with TIO/OLO or FF/UMEC/VI initiated during the patient 
identification period of 01 June 2015 to 30 November 2019. The index date will be 
the date of the TIO/OLO or FF/UMEC/VI pharmacy claim that starts the ≥30 
consecutive days with the medication.

≥1 facility claim with a diagnosis of COPD in the primary position or ≥2 professional 
claims with a diagnosis code for COPD (Annex 3) in any position on separate dates of 
service during the study period

≥40 years of age as of the year of the index date

Continuous enrollment with medical and pharmacy coverage for 12 months prior to 
and including the index date (baseline period)

Continuous enrollment with medical and pharmacy coverage for ≥30 days following 
the index date and without discontinuation of the index medication or switch to a non-
index regimen (follow-up period); discontinuation and switch are defined in Section 
9.2.1.

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Exclusion Criteria

≥2 medical claims with a diagnosis code for asthma, cystic fibrosis, lung cancer, or 
interstitial lung disease (Annex 3) in any position on separate dates of service during 
the baseline period 

Pharmacy claims for both TIO/OLO and FF/UMEC/VI on the index date

A pharmacy claim for any non-index COPD maintenance medication on the index 
date, defined as: LAMA monotherapy; LABA monotherapy; ICS monotherapy; FDC 
ICS/LABA, or FDC LAMA/LABA (Annex 3)

Free or fixed dose LAMA+LABA maintenance therapy defined as ≥7 consecutive 
days of overlapping days’ supply with a LAMA and LABA during a 6-month pre-
index period, excluding the index date (Annex 3) 

Flags will be created to identify patients excluded for baseline LAMA/LABA use 
overall and specifically for each FDC LAMA/LABA medication

Free or fixed dose TT defined as ≥7 consecutive days of overlapping days’ supply 
with an ICS, LABA, and LAMA during a 6-month pre-index period, excluding the 
index date (Annex 3) 

≥1 medical claim with a procedure code for lung volume reduction during the study 
period (Annex 3)

Unknown age, gender, or business line, or unknown/other geographic region
The exclusion criteria for previous medication use was relaxed to ≥7 consecutive days of 
overlapping days’ supply rather than ≥1 day of overlapping days’ supply based on the 
number of patients excluded in the attrition table. This decision was made after reviewing the 
attrition tables using the two criteria and before any baseline or follow-up analyses were 
completed. 
Study inclusion and exclusion criteria will be finalized during review of the patient attrition 
table, and prior to any baseline or follow-up analyses. 
9.2.4.1 Patient Identification – Eosinophil Subgroup 
To be included in the subgroup analysis of patients with at least one eosinophil lab result, 
patients will be required to meet the patient identification criteria outlined in Section 9.2.4. as 
well as having at least one eosinophil lab result in the six months prior to the index date 
(index date – 179 days) through 15 days after the index date (index date + 15 days). 
Additionally, the number of patients with ≥1 eosinophil result in the three months prior the 
index date (index date – 89 days) through to the index date will be identified. The time period 
for identification of ≥1 eosinophil result will be determined based on the number of patients 
identified during these time windows. 
Eosinophil test results will be categorized, according to the eosinophil test result closest to 
the index date during the time period of interest (i.e., with the smallest absolute difference in 
days between the lab date and the index date), as >300 cells/µL or ≤300 cells/µL. For 
multiple eosinophil laboratory results on the same date of service, the highest value will be 
retained.

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9.2.5
Study visits
Not applicable
9.2.6
Study discontinuation
Not applicable
VARIABLES
9.3.1
Exposures
Patients will be assigned to one of the following mutually exclusive study cohorts based on 
the index pharmacy claim: TIO/OLO or FF/UMEC/VI. 
9.3.2
Outcomes
9.3.2.1 Primary outcomes
The following outcomes will be measured in the baseline and follow-up periods. The baseline 
period will include claims occurring on the index date, except for the index medication 
claims, which will be included in the follow-up period. 

All-cause health care resource utilization: Indicator variables and counts of 
physician office visits, hospital outpatient visits, ED visits, “other” (non-inpatient) 
visits, inpatient stays, and pharmacy claims will be created. Other medical visits are a 
residual category that includes, but is not limited to, services rendered at independent 
laboratories, assisted living facilities, and by home health providers. An indicator 
variable will be created to identify inpatient stays with an acute stay during the 
inpatient admission. The length of inpatient stays will also be captured. The time to 
first inpatient stay, the time to first inpatient stay with an acute stay, and the time to 
first ED visit during follow-up will be captured. 

COPD and/or pneumonia-related health care resource utilization: This utilization 
will be calculated analogously to all-cause utilization, but restricted to medical claims 
with a diagnosis for COPD, pneumonia, or acute bronchitis/bronchiolitis in any 
position (Annex 3) and pharmacy claims for a COPD-related treatment (Annex 3), 
including COPD-guideline recommended antibiotics (Annex 3).

COPD-related health care resource utilization: This utilization will be calculated 
analogously to all-cause utilization, but restricted to medical claims with a diagnosis 
for COPD in any position (Annex 3) and pharmacy claims for a COPD-related 
treatment  (Annex 3), including COPD-guideline recommended antibiotics (Annex 3).

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
Pneumonia-related health care resource utilization: This utilization will be 
calculated analogously to all-cause utilization, but restricted to medical claims with a 
diagnosis for pneumonia in any position (Annex 3).

COPD or pneumonia-attributable health care resource utilization: This 
utilization will be calculated analogously to all-cause utilization, but restricted to 
medical claims with a diagnosis for COPD, pneumonia, or acute 
bronchitis/bronchiolitis in the primary position or a diagnosis for acute respiratory 
failure in the primary position and a diagnosis for COPD, pneumonia, or acute 
bronchitis/bronchiolitis in a non-primary position (Annex 3) and pharmacy claims for 
a COPD-related treatment (Annex 3), including COPD-guideline recommended 
antibiotics (Annex 3). 

All-cause health care costs (insurer + patient paid amounts): Health care costs 
will be computed from the payer and patient perspective together. This is the actual 
amount paid to the provider by the health plan plus the patient copay and/or 
coinsurance amounts, rather than an estimated cost. Total costs will be calculated and 
presented as the combined pharmacy costs and medical costs. Medical costs will be presented 
and will include sub-categories of physician office costs, hospital outpatient costs, emergency 
services costs, inpatient costs, and other costs. 

Costs will be adjusted to 2020 dollars using the medical care component of the 
Consumer Price Index (CPI) to reflect inflation between the date of the claim and 
2020 [R21-4317]. The final report will include additional columns with the latest 
available 2021 mid-year CPI adjustment applied to costs for scaling the results as 
needed.

Costs from other payers may be important, particularly for studies involving older 
patients dually eligible for commercial and Medicare coverage. In consultation 
with BIPI, this study will NOT incorporate the amounts estimated to be paid by 
other payers for a total paid or allowable amount [P21-11033].

COPD and/or pneumonia-related health care costs (insurer + patient paid 
amounts): These costs will be calculated analogously to the all-cause costs, but 
restricted to medical claims with a diagnosis for COPD, pneumonia, or acute 
bronchitis/bronchiolitis in any position (Annex 3) and pharmacy claims for a COPD-
related treatment (Annex 3), including COPD-guideline recommended antibiotics 
(Annex 3).

COPD-related health care costs (insurer + patient paid amounts): These costs 
will be calculated analogously to the all-cause costs, but restricted to medical claims 
with a diagnosis for COPD in any position (Annex 3) and pharmacy claims for a 
COPD-related treatment (Annex 3), including COPD-guideline recommended 
antibiotics (Annex 3).

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
Pneumonia-related health care costs (insurer + patient paid amounts): These 
costs will be calculated analogously to the all-cause costs, but restricted to medical 
claims with a diagnosis for pneumonia in any position (Annex 3).

COPD or pneumonia-attributable health care costs (insurer + patient paid 
amounts): These costs will be calculated analogously to the all-cause costs, but 
restricted to medical claims with a diagnosis for COPD, pneumonia, or acute 
bronchitis/bronchiolitis in the primary position or a diagnosis for acute respiratory 
failure in the primary position and a diagnosis for COPD, pneumonia, or acute 
bronchitis/bronchiolitis in a non-primary position (Annex 3) or pharmacy claims for a 
COPD-related treatment (Annex 3), including COPD-guideline recommended 
antibiotics (Annex 3).  

COPD exacerbations: Exacerbations will be categorized as moderate or severe and a 
count of any (severe or moderate), severe, and moderate will be provided. The time to 
first severe exacerbation, and time to first exacerbation (severe or moderate), during 
follow-up will be captured. Diagnosis codes that will be used to identify exacerbation-
related medical visits are included in Annex 3. COPD-related treatments are listed in 
Annex 3 and COPD-guideline recommended antibiotics are listed in Annex 3. Details 
of the exacerbation definition are provided in Annex 3. 

A severe exacerbation will be defined as follows:
An inpatient admission or an ER visit with a COPD diagnosis code in the 
primary position; or 
An inpatient admission or an ER visit with a diagnosis code for acute 
respiratory failure in the primary position and a COPD diagnosis code in any 
position; or 
An inpatient admission or an ER visit with a diagnosis code for acute 
respiratory failure in the primary position + an inpatient admission or an ER 
visit within ±7 days with a COPD diagnosis code in any position. 

A moderate exacerbation will be defined as follows: 
An ambulatory (office or outpatient) visit with a COPD diagnosis code in any 
position + a pharmacy claim for an oral corticosteroid (OCS) prescription within 
±7 days of the office/outpatient visit; or 
An office or outpatient visit with a COPD diagnosis code in any position + a 
pharmacy claim for COPD-guideline recommended antibiotic prescription 
within ±7 days of the office/outpatient visit; or 
An office or outpatient visit with a COPD diagnosis code in any position + a 
pharmacy claim for an OCS + a pharmacy claim for COPD-guideline 
recommended antibiotic prescription within ±7 days of the office/outpatient 
visit. 

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
Baseline GOLD exacerbation history: Indicator variables will be created to identify 
patients with no baseline exacerbation or 1 baseline exacerbation not leading to 
hospitalization (i.e. baseline GOLD A/B) and with ≥2 baseline exacerbations not 
leading to hospitalization or ≥1 baseline exacerbation leading to hospitalization (i.e. 
baseline GOLD C/D). These baseline GOLD classification variables will be used to 
classify the patient population for analysis by exacerbation history.

Baseline exacerbation not leading to hospitalization will be defined as follows: 
An ER visit with a COPD diagnosis code in the primary position; or 
An ER visit with a diagnosis code for acute respiratory failure in the primary 
position and a COPD diagnosis code in any position; or 
An ER visit with a diagnosis code for acute respiratory failure in the primary 
position + an ER visit within ±7 days with a COPD diagnosis code in any 
position; or
An ambulatory (office or outpatient) visit with a COPD diagnosis code in any 
position + a pharmacy claim for an oral corticosteroid (OCS) prescription within 
±7 days of the office/outpatient visit; or 
An office or outpatient visit with a COPD diagnosis code in any position + a 
pharmacy claim for COPD-guideline recommended antibiotic prescription 
within ±7 days of the office/outpatient visit; or 
An office or outpatient visit with a COPD diagnosis code in any position + a 
pharmacy claim for an OCS + a pharmacy claim for COPD-guideline 
recommended antibiotic prescription within ±7 days of the office/outpatient 
visit. 

Baseline exacerbation leading to hospitalization will be defined as follows:
An inpatient admission with a COPD diagnosis code in the primary position; or 
An inpatient admission with a diagnosis code for acute respiratory failure in the 
primary position and a COPD diagnosis code in any position; or 
An inpatient admission with a diagnosis code for acute respiratory failure in the 
primary position + an inpatient admission or an ER visit within ±7 days with a 
COPD diagnosis code in any position; or
An ER visit with a diagnosis code for acute respiratory failure in the primary 
position + an inpatient admission within ±7 days with a COPD diagnosis code 
in any position.

Pneumonia diagnosis: Binary indicators will be created to identify patients with a 
diagnosis of 1) pneumonia or 2) pneumonia or acute bronchitis/bronchiolitis in any 
position (Annex 3). The time to first pneumonia diagnosis, and time to first 
pneumonia or acute bronchitis/bronchiolitis diagnosis, during follow-up will also be 
captured. 

Pneumonia-related hospitalization: Binary indicators will be created to identify 
patients with an acute hospitalization with diagnosis of 1) pneumonia or 2) pneumonia 
or acute bronchitis/bronchiolitis in any position (Annex 3). The time to first 

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pneumonia-related acute hospitalization, and time to first pneumonia- or acute 
bronchitis/bronchiolitis-related acute hospitalization, during follow-up will also be 
captured. 

COPD exacerbation and/or pneumonia diagnosis: Binary indicators will be created 
to identify patients with each of the following composite outcomes: severe COPD 
exacerbation or an acute hospitalization with a diagnosis of pneumonia in any 
position, severe COPD exacerbation or an acute hospitalization with a diagnosis of 
pneumonia or acute bronchitis/bronchiolitis in any position, any COPD exacerbation 
or pneumonia diagnosis in any position, and any COPD exacerbation or pneumonia 
diagnosis or acute bronchitis/bronchiolitis diagnosis in any position. Time to event 
variables will be created for each composite outcome during the follow-up period.
9.3.2.2 Secondary outcomes
COPD readmission (Centers for Medicare and Medicaid Services [CMS] definition): 
COPD readmissions, based on the 2017 CMS specifications as described below [R21-4119],
will be captured.

COPD-related hospitalizations will be identified during the patient’s follow-up. 
Hospitalizations will be classified as COPD-related if they met either of the 
following 2 criteria: 
≥1 diagnosis of COPD (Annex 3) in the primary position any time during the 
acute inpatient stay; or
≥1 diagnosis of acute respiratory failure (Annex 3) in the primary position and a 
diagnosis of acute exacerbation of COPD (Annex 3) in a later position on the 
same claim during an acute inpatient stay.

For each qualifying COPD-related hospitalization, an indicator variable will be 
created to identify if there was a re-admission that started within 30 days of the 
discharge of the COPD-related hospitalization.

COPD-related hospitalizations will be required to have at least 30 days of 
enrollment after the discharge to be included in the analysis, unless readmission 
and death occur within 30 days of hospital discharge. Hospitalizations that ended 
within 30 days of the end date will be not included because readmission status 
cannot be determined accurately. 

COPD-related hospitalizations that ended because the patient discharged 
themselves against medical advice will be excluded from the analysis, and all-
cause hospitalizations that included procedures and diagnoses (Annex 3) that are 
always considered planned (i.e., transplant surgery, maintenance 
chemotherapy/immunotherapy, and rehabilitation) will not be eligible to be a 
readmission.

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9.3.3
Covariates
9.3.3.1 Clinical Characteristics 
Clinical characteristics will be measured in the baseline period. The baseline period will 
include claims occurring on the index date, except for the index medication claims, which 
will be included in the follow-up period.

Quan-Charlson comorbidity score: A comorbidity score will be calculated 
based on the presence of diagnosis codes (in any position) on medical claims in 
the baseline period [R21-4087; R20-2288; R14-4775]. The score is calculated 
based on a weighted sum of 12 comorbid conditions. The score represents the
cumulative likelihood of one-year mortality and serves as a proxy for comorbidity 
burden. The Quan-Charlson comorbidity score also will be categorized into the 
following groups: zero, one, two, three, four, and five or more.

Charlson Comorbidity Score without COPD: In addition to the standard 
Charlson comorbidity score, a modified score removing COPD diagnosis 
codes will be calculated.

Elixhauser score: The Elixhauser score will be calculated based on the presence 
of diagnosis codes (any position) on medical claims during the baseline period
[R13-3591]. Elixhauser comorbidities will be consolidated into a single numeric 
score to summarize disease burden [R21-4090] The score is calculated based on a 
weighted sum of 31 comorbid conditions. The score represents the likelihood of 
hospital mortality, and serves as a proxy for comorbidity burden, similar to the 
Charlson score.

Elixhauser score without COPD: A modified score removing COPD 
diagnosis codes will also be calculated.

COPD Severity Score: The COPD Severity score will be calculated as a 
weighted sum of the individual components listed in Table 1 during the baseline 
period [R21-4086] . The COPD Severity score is a validated measure of COPD 
severity based on treatments.

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Table 1
COPD Severity Score Components
Component (input from 
claims)
How Identified in Claims
Count of exacerbations 
See definition for COPD Exacerbations above
Oxygen therapy – current
CPT, HCPCS, ICD-10, ICD-9 and revenue codes
Length of stay for COPD-
attributable inpatient 
visits
ICD-9 or ICD-10 code for COPD in the primary position or a 
code for acute respiratory failure in the primary position and a 
code for COPD in a non-primary position 
Emphysema 
ICD-9 or ICD-10 code in any position on a medical claim
Spirometry testing 
See Spirometry Testing, below
Pulmonologist visits 
Physician specialty
Use of SAMAs (including 
SABA/SAMA
combination)
See Medication Utilization, above
Use of oral corticosteroids See Medication Utilization, above
Use of inhaled 
corticosteroids 
See Medication Utilization, above
Use of SABAs (including 
SABA/SAMA 
combination) 
See Medication Utilization, above
Use of long-acting 
bronchodilators 
See Medication Utilization, above
Mean age
Age as of baseline year 

Additional comorbid conditions: Additional comorbid conditions, including allergic 
rhinitis, anxiety (narrow and broad), arrhythmia, atrial fibrillation (narrow and broad), 
acute sinusitis, candidiasis, cataracts, chronic sinusitis, chronic rhinitis, congestive 
heart failure, depression, diabetes (type I and II), dyspnea, hypertension, ischemic 
heart disease, metabolic syndrome (including individual components), myocardial 
infarction, osteoporosis, pulmonary fibrosis, peripheral vascular disease, peptic 
ulcer/GERD, renal disease, sleep apnea, stroke, pneumonia, and pneumonia or acute 
bronchitis/bronchiolitis will also be identified based on the presence of a diagnosis 
code in any position on a medical claim (Annex 3). 

Oxygen therapy: Evidence of oxygen use will be captured in the baseline period 
based on diagnosis (ICD-9, ICD-10), procedure (HCPCS, CPT, ICD-9) and revenue 
codes for oxygen therapy (Annex 3).

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
Baseline respiratory medication utilization: Indicator variables for respiratory 
medication classes and selected individual respiratory medications will be based on 
both pharmacy and medical claims (nebulizer treatments may appear in medical 
claims). Medication classes will include: LAMAs (alone; overall and separately), 
LABAs (alone), ICS (alone), ICS/LABA single inhaler combination medications, 
SAMAs (alone), SABAs (alone), SAMA/SABA single inhaler combination 
medications, any rescue (SAMA alone, SABA alone, or SAMA/SABA single inhaler 
combination medications), methylxanthines, phosphodiesterase-4 (PDE-4) inhibitors 
and oral corticosteroids (OCS). Baseline medication use variables will exclude claims 
which make up the index therapy assignment. Number of fills by class will also be 
captured. Indicator variables will be created to identify patients who are naïve to long-
acting bronchodilators (free or fixed dose LAMAs or LABAs) and to long-acting 
bronchodilators plus inhaled corticosteroids (free or fixed dose LAMAs, LABAs, and 
ICSs) at index.

Index provider specialty: The specialty of the provider on the index prescription fill 
will be captured. If no provider specialty is recorded on the index prescription fill, the 
provider specialty from the most recent COPD-related visit on or prior to the index 
date will be captured. An indicator variable will identify if the provider specialty was 
determined from the index pharmacy claim. Provider specialty will be classified as 
one of the following: pulmonology, primary care [family practice, general practice, 
and geriatrics], internal medicine, allied health professional, cardiology, other 
specialty, and unknown specialty. If claims for more than one provider occur on the 
date used to classify the provider’s specialty, the hierarchy of categories listed above 
will be used to pick a single provider specialty.

Pulmonology visit within 30 days of index date: An indicator variable will be 
created to identify patients with a pulmonologist visit within 30 days prior to and 
excluding the index date.

Spirometry testing: Indicator and count variables will be created to identify patients 
with lung function testing (Annex 3). A count of spirometry tests during the baseline 
period will be created. 

Early adopter of index medication: An indicator variable will be created to identify 
patients with an index date within 90 days of FDA approval of the medication. The 
FDA approval date is specific to the index therapy: Stiolto Respimat (TIO/OLO) was 
FDA approved on 21 May 2015 and Trelegy Ellipta (FF/UMEC/VI) was FDA 
approved on 18 September 2017.

Evidence of tobacco use: An indicator variable will be created to identify patients 
with evidence of current or prior tobacco use based on diagnosis codes (Annex 3) or 
pharmacy fills for smoking cessation treatments (bupropion, varenicline tartrate, or 
nicotine inhalation system). 

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9.3.3.2 Patient Characteristics 
Patient characteristics will be measured as of the index date, or the first available claim after 
the index date with valid values for each of the characteristics. Approval through the 
 
data disclosure analysis process is required for inclusion of socioeconomic data (i.e., 
race/ethnicity) and resource scare areas. Approval is not guaranteed. It may be necessary to 
modify or remove some variables or analytic table templates in order to preclude 
identification of individual patients and protect proprietary health plan information. 

Index year: The year of the patient’s index date will be identified.

Seasonality: The month of the patient’s index date will be identified and classified as 
fall (September, October, November), winter (December, January, February), spring 
(March, April, May), or summer (June, July, August).

Age: Age will be defined as of the index year

Age groups: Patients will be assigned to one of the following age groups: 40-49, 50-
59, 60-64, 65-69, 70-74 and 75+

Gender: Gender will be captured from enrollment data; patients with undefined 
gender will be removed from the study sample

Race/ethnicity: Race/ethnicity information will be captured from the linked 
consumer sociodemographic data and categorized as follows: White, African-
American/Black, Asian, Hispanic, or unknown (unknown includes missing). This 
variable depends on the availability of data within the sociodemographic data and will 
be missing for some patients.

Insurance type: Whether the patient was covered under a commercial or Medicare 
Advantage health plan will be captured

Plan type: Plan type will be categorized as Exclusive Provider Organization (EPO), 
Health Maintenance Organization (HMO), Point of Service (POS), Preferred Provider 
Organization (PPO), Individual and Other

Geographic region: The US region in which the study patient is enrolled in a health 
plan will be determined and reported and states will be categorized into five 
geographic regions in accordance with the US Census Bureau’s region designations; 
the five health plan regions are presented in the table below. Patients categorized into 
“other” will be excluded from the study.

Resource scarce area: Health professional shortage areas (HPSAs) will be identified 
based on the Health Resources and Services Administration designation of geographic 
regions with a shortage of providers to meet the needs of the population [R21-4295].

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Table 2
Health Plan Regions
Region
State
Northeast
CT, MA, ME, NH, RI, VT, NJ, NY, PA
Midwest
IL, IN, MI, OH, WI, IA, KS, MN, MO, ND, NE, SD
South
DC, DE, FL, GA, MD, NC, SC, VA, WV, AL, KY, MS, TN, AR, LA, 
OK, TX
West
AZ, CO, ID, MT, NM, NV, UT, WY, AK, CA, HI, OR, WA
DATA SOURCES
9.4.1
Database
The 
 Database (
D), is fully de-identified and HIPAA compliant, and 
comprised of medical and pharmacy claims data (including linked enrollment information) 
from 1993 to present on more than 73 million lives. 
In 2018, the 
D included claims for approximately 19% of the US commercially enrolled 
population and approximately 21% of the Medicare Advantage population (commonly 
referred to as the Medicare Advantage program [Medicare Part C]) through an offering 
associated with 
 Medicare Advantage enrollees choose to receive all of their health 
care services through a provider organization in lieu of Medicare Part A/B coverage 
(commonly referred to as Medicare Fee for Service). These plans are referred to as MAPD 
when combined with Medicare Part D coverage. 
Underlying information is geographically diverse across the United States and enrollees are 
fairly representative of the US population. Because the 
D is a closed system, patients 
retain a single identifier within the system and can be tracked as they change plans, or as they 
disenroll and reenroll over time.
Claims for pharmacy services are typically submitted electronically by the pharmacy at the 
time prescriptions are filled. The claims history is a profile of all outpatient prescription 
pharmacy services provided and covered by the health plan. Pharmacy claims data include 
drug name, dosage form, drug strength, fill date, days of supply, financial information, and 
de-identified patient and prescriber codes, allowing for longitudinal tracking of medication 
refill patterns and changes in medications. Pharmacy claims are typically added to the 
research database within six weeks of dispensing.
Medical claims or encounter data are collected from all available health care sites (inpatient 
hospital, outpatient hospital, emergency department, physician's office, surgery center, etc.) 
for virtually all types of provided services, including specialty, preventive and office-based 
treatments. Medical claims and coding conform to insurance industry standards. Claims for 
ambulatory services submitted by individual providers, such as physicians, use the Health 

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Care Financing Administration (HCFA)-1500 or Centers for Medicare and Medicaid Services 
(CMS)-1500 formats. Claims for facility services submitted by institutions, e.g., hospitals, 
use the Uniform Billing (UB)-82, UB-92, UB-04, or CMS-1450 formats. Medical claims 
include: multiple diagnosis codes recorded with the International Classification of Diseases, 
Ninth Revision, Clinical Modification (ICD-9-CM) and International Classification of 
Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) diagnosis codes; procedures 
recorded with ICD-9-CM and ICD-10-CM procedure codes, Current Procedural Terminology 
(CPT), or Health care Common Procedure Coding System (HCPCS) codes; site of service 
codes; provider specialty codes; revenue codes (for facilities); paid amounts; and other 
information. Typically, facility claims do not include medications dispensed in hospital. 
Approximately six months following the delivery of services is required for complete medical 
data.
9.4.2
Laboratory Results
Outpatient laboratory test results are available for subpopulations of the research database. 
Standard LOINC coding is used to define specific tests and results. Test results data can be 
linked to the other health care utilization and pharmacy claims data in the research database. 
Results included in the database are typically from blood-based tests (e.g., LDL, HbA1c) that 
are sent for processing to one of several laboratory facilities in the country that provide 
services to enrollees in the health plan. For common blood-based tests such as lipids and 
HbA1c, results are typically available for approximately 40-50% of tests performed. 
However, this proportion varies by test and by disease state. In addition, study requirements 
such as the timing of the laboratory result or the requirement of multiple results to assess 
change over time will be available for smaller subsets of the study population. Results dating 
back to 2000 are available for research.
Laboratory results are typically added to the research database within three to six months of 
administration of the test.
STUDY SIZE
Using claims data for commercial and Medicare Advantage health plan enrollees we 
identified 5,717 and 17,733 patients who initiated treatment with TIO/OLO or FF/UMEC/VI, 
respectively, between 01 January 2018 and 31 July 2019. These patients had 12-months of 
baseline and ≥30 days of follow-up continuous enrollment with both medical and pharmacy 
coverage. This count is for informational purposes only and may not represent the actual 
number of patients to be utilized in the study. Application of other inclusion and exclusion 
criteria required for this study or other factors may reduce the sample size.
DATA MANAGEMENT
Not applicable

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DATA ANALYSIS
All statistical analyses will be performed by 
 using 
, 
) or later. The conventional significance level α=0.05 will be used to determine statistical 
significance.
9.7.1
Comparison of TIO/OLO Initiators
Given the difference in FDA approval dates (May 2015 for TIO/OLO and September 2017 
for FF/UMEC/VI) and concerns about retaining adequate sample size for the analyses the 
following stepwise approach will be implemented to finalize the patient identification period
.
1) In the overall population, TIO/OLO initiators from May 2015 – December 2017 
will be compared to TIO/OLO initiators from January 2018 – November 2019 on 
a prespecified list of characteristics including:
Demographics (age in years, gender, geographic region, insurance type 
[commercial vs. MAPD], prescriber specialty, pulmonologist visit within 30 
days prior to and excluding the index date)
Clinical comorbidities (diabetes, hypertension, ischemic heart disease, 
Elixhauser score without COPD) 
COPD severity proxies (dyspnea, oxygen therapy, maintenance naïve, no 
baseline exacerbation or 1 baseline exacerbation not leading to hospitalization, 
≥2 baseline exacerbations not leading to hospitalization or ≥1 baseline 
exacerbation leading to hospitalization) 
2) If TIO/OLO initiators from before and after FF/UMEC/VI approval are well 
balanced (i.e., standardized difference ≤10%) across all characteristics outlined in 
step one, the start of the patient identification period will remain 01 June 2015. 
3) If TIO/OLO initiators from before and after FF/UMEC/VI approval have 
standardized differences >10% on one to three characteristics listed in step one, 
those characteristics will be included as covariates in post-match multivariable 
regression analysis. 
4) If TIO/OLO initiators from before and after FF/UMEC/VI approval have 
standardized differences >10% on four or more characteristics listed in step one, 
the start of the patient identification period will be moved from 01 June 2015 to 
01 January 2018. 
9.7.2
Main analysis
Not applicable

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9.7.3
Primary Objectives
9.7.3.1 Descriptive Analysis
Baseline categorical variables will be presented as numbers and percentages and baseline 
continuous variables will be presented as means, standard deviations, medians, and 
interquartile ranges. Follow-up variables will be presented as population annualized averages 
to account for the variable follow-up duration (minimum 1 month, maximum 12 months). 
Population annualized averages will be calculated as ([sum of all utilization or cost for all 
individuals during the follow-up period]/[sum of all follow-up time in days for all 
individuals])*365. Wald 95% confidence intervals (CI) will be provided for annualized 
population averages using the Taylor expansion to estimate the standard error. The numerator 
and denominator of the population annualized average equation and the 95% CI will be 
presented. Per patient per month calculations will not be performed. Appropriate statistical 
tests comparing treatment cohorts (e.g., t-test, chi-square test) will be used based on the 
distribution of the measure (Table 3)
Bivariate comparisons of patient demographics and baseline characteristics will be provided 
for the TIO/OLO and FF/UMEC/VI cohorts prior to PSM. Following the matching 
procedure, bivariate comparisons of demographics and baseline characteristics will be 
provided to assess the success of the matching procedure, and comparisons of outcomes will 
be provided to assess the impact of initiating treatment with TIO/OLO vs FF/UMEC/VI. 
Appropriate tests comparing the TIO/OLO cohort and the FF/UMEC/VI cohort (e.g., 
standardized differences, McNemar’s tests, paired t-tests, sign tests) (Table 3) will be used 
based on the distribution of the measure. Patients not matched will be excluded from the post-
match analysis. In addition to presenting the results stratified by treatment cohort (TIO/OLO 
vs. FF/UMEC/VI), the results will be presented stratified by treatment cohort among the 
following populations: maintenance naïve (patients with no baseline maintenance medication 
[no free or fixed dose LAMA, LABA, or ICS]); no exacerbation (patients with no baseline 
exacerbation); no exacerbation or one exacerbation not leading to hospitalization (i.e., 
baseline GOLD A/B); at least two exacerbations not leading to hospitalization or at least one 
exacerbation leading to hospitalization [i.e., baseline GOLD C/D]). Results also will be 
presented for the subset of the population with at least one eosinophil laboratory result.

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Table 3
Statistical Testing by Descriptive Variable Type 
Variable type
Baseline 
Variable follow-up 
comparisons between study 
cohorts
Categorical
Pearson’s chi-square 
Fisher’s exact test
Kaplan-Meier
Continuous
Independent samples t-test 
Wilcoxon-Mann Whitney 
test
Population annualized averages 
Time-to-event variables
N/A
Incidence rate or Kaplan-Meier
9.7.3.2 Kaplan Meier Analysis
Kaplan–Meier (KM) analysis will be used to estimate time to first COPD exacerbation (any, 
severe), time to first pneumonia diagnosis, and time to first pneumonia hospitalization. When 
KM analysis is conducted, results will include censored-adjusted percentage of patients who 
have had at least one event of interest (i.e., COPD exacerbation, pneumonia diagnosis, 
pneumonia hospitalization) at pre-specified time periods of interest (e.g., 1 month, 3 months, 
6 months). In addition, the median (and 25th and 75th percentile) time to event and the 95% 
confidence interval around the median (and 25th and 75th percentile) will be reported. A p-
value will be calculated using the log rank test to examine if the distribution of outcomes 
among patients in the TIO/OLO cohort versus the FF/UMEC/VI cohort are different. In 
addition to presenting results for the overall TIO/OLO versus FF/UMEC/VI comparison, KM 
analysis also will be conducted among the following populations: maintenance naïve; no 
exacerbation; no exacerbation or one exacerbation not leading to hospitalization; at least two 
exacerbations not leading to hospitalization or at least one exacerbation leading to 
hospitalization; subset of the population with at least one eosinophil laboratory result.
9.7.3.3 Number Needed to Treat
Based on the descriptive analysis results, the number of FF/UMEC/VI patients that would 
instead need to be treated (i.e., number needed to treat [NNT]) with TIO/OLO to avoid one 
event (e.g., exacerbation of COPD) will be calculated for key outcomes. The NNT will be 
calculated using the following equation: 1/(Event RateFF/UMEC/VI – Event RateTIO/OLO). 
Rates will be derived from the annualized Kaplan-Meier analyses.
9.7.3.4 Multivariable Analysis (Optional)
Multivariable regression will be included in the analysis if either TIO/OLO initiators from 
before and after FF/UMEC/VI approval have standardized differences of >10% on one to 
three characteristics listed in Section 9.7.1. or if there are standardized differences of >10% 

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between the TIO/OLO and FF/UMEC/VI cohorts after PSM. If multivariable model is 
included, the appropriate regression model will be selected based on the distribution of the 
measure. Because health care costs are often skewed, cost measures may be modeled using 
Manning and Mullahy's formulation.  This method avoids potential difficulties introduced by 
transformation and retransformation of the dependent variable.  Specifically, the outcome is 
modeled employing a GLM with a gamma distribution and log link. Exponentiated 
coefficients from a GLM are estimated cost ratios. Cost ratios, 95% confidence intervals, and 
p-values will be presented for each covariate included in the final model. For ease of 
interpretation and comparison with the bivariate results, the average cost will be predicted for 
each cohort using recycled predictions. Cox proportional hazard modeling may be used for 
the exacerbation and pneumonia outcomes.
9.7.4
Secondary Objective
9.7.4.1 COPD Readmission CMS Definition

CMS-based readmission analysis will not be conducted for the subgroup analysis 
among patients with available eosinophil lab results.
A hospitalization-level analysis will be performed to examine how many COPD-related 
hospitalizations resulted in an all-cause inpatient readmission within 30 days of discharge. 
The sample size for this analysis will be the number of qualifying COPD-related 
hospitalizations that occur during the follow-up, and consequently a patient may contribute 0, 
one, or more than one observation to the analysis. A patient with no COPD-related 
hospitalizations will not contribute any observations to the analysis, and a patient with two 
COPD-related hospitalizations five months apart may contribute two observations to the 
analysis. The number and percent of follow-up COPD-hospitalizations that result in an all-
cause readmission will be calculated. An unmatched descriptive analysis will be conducted 
because the unit of analysis will be hospitalizations, not patients. Logistic regression will be 
conducted to determine if the adjusted odds of a readmission are different for hospitalizations 
among TIO/OLO initiators versus hospitalizations among FF/UMEC/VI initiators. The 
logistic regression model will include the propensity score model covariates, plus an 
additional baseline readmission covariate. A variable will be created to identify if the person 
associated with the hospitalization had: 1) at least one baseline COPD hospitalization that 
resulted in a readmission; 2) at least one baseline COPD hospitalization but none of them 
resulted in a readmission; 3) no baseline COPD-related hospitalization. The logistic 
regression model will account for clustering since patients could contribute multiple 
observations (i.e., multiple qualifying COPD hospitalizations).

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LIMITATIONS OF THE RESEARCH METHODS
An inherent limitation of observational studies involving non-random allocation of treatment 
is a form of selection bias called ‘confounding by indication’. With this type of selection bias, 
the underlying patient characteristics associated with a certain treatment (i.e., TIO/OLO or 
the comparator) may influence the outcome under study. The current study proposes to 
address the bias from confounding by indication with PSM. The aim of PSM is to balance 
two non-equivalent groups on observed baseline characteristics to be able to obtain less 
biased estimates of treatment effects. This balancing can be achieved by either matching 
study patients in comparison groups on propensity scores, weighting for propensity scores, or 
adjusting for propensity scores in the analysis. This therefore ensures that the distribution of 
characteristics is the same for patients who initiate TIO/OLO and FF/UMEC/VI.
Second, an “on-treatment” analysis is planned in which patients will be censored at the time 
of discontinuation of the index medications or initiation of another COPD maintenance 
medication (as well as for disenrollment from the health plan, 12-months following the index 
date, or the end of the study period). Therefore, the conclusions from this study will be 
applicable to patients who initiate and remain on the study treatments, rather than the broader 
population of patients who initiate one of the study treatments (i.e., an intention to treat 
analysis) and therefore is potentially prone to survival bias. By censoring at the time of 
discontinuation of the index medication rather than the discontinuation date + 30 days 
outcomes that occur right after medication discontinuation, which may be related to the index 
medication, are not captured.
Third, patients with one or more days of free or fixed dose LAMA/LABA maintenance 
therapy in the six month pre-index period will be excluded from the study sample. The 
GOLD 2018 and 2019 recommendations maintain that TT should only be used as an 
escalation step following treatment with LAMA and LABA or LABA and ICS. Thus, patients 
initiating FF/UMEC/VI in this study, will be a subset of TT initiators who are not following 
the GOLD recommendations. 
Fourth, the patient identification period starts at the FDA approval of TIO/OLO (May 2015) 
rather than the FDA approval of FF/UMEC/VI (September 2017). By design, patient index 
year will not be included/ as a matching variable for the PSM models because there will be 
no FF/UMEC/VI initiators to match in the first part of the patient identification period. 
TIO/OLO initiators from May 2015 – December 2017 will be compared to TIO/OLO 
initiators from January 2018 – November 2019 on a prespecified list of characteristics as 
outlined in Section 9.7.1. If there are differences between TIO/OLO initiators from before 
and after FF/UMEC/VI approval the start of the patient identification period will be moved to 
01 January 2018. Index year may be included in multivariable regression analysis to 
determine if the index year (i.e., initiation date) is a confounder of the association between 
treatment and outcomes. If index year is a significant predictor in the multivariable regression 
model, sample selection may be restricted to patients with an index date following 
FF/UMEC/VI launch or the sample may be restricted to a time period where index year is not 
a significant covariate in the multivariable regression model.

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Finally, claims data are subject to certain limitations. In addition to miscoding, omissions 
and/or rule-out diagnoses, the presence of a claim for a filled prescription does not indicate 
that the medication was consumed or that it was taken as prescribed, and any medications 
filled over-the-counter or provided as samples by the physician will not be observed in the 
claims data. It also lacks some lifestyle behaviors and clinically relevant characteristics 
including lung function, smoking status/history, symptom burden that may impact disease 
progression and in turn the outcome metrics. Data on physician decision-making process on 
treatment choices is also unavailable and may impact our comparison of an initial vs. a next-
in-line treatment. Relying on pharmacy claims for switch and discontinuation definitions will 
miss patients who use nebulized medications captured via medical claims and may 
preemptively censor adherent patients. Finally, as with all claims-based analyses, study 
results may not be generalizable to those with non-commercial or MAPD health insurance.
OTHER ASPECTS
None
9.9.1
Data quality assurance
A quality assurance audit/inspection of this study may be conducted by the sponsor or 
sponsor’s designees or by Institutional Review Board (IRBs) / Independent Ethics Committee 
(IECs) or by regulatory authorities. The quality assurance auditor will have access to all 
medical records, the investigator’s study-related files and correspondence, and the informed 
consent documentation of this study.
9.9.2
Study records
9.9.2.1 Source documents
Not applicable

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10.
PROTECTION OF HUMAN SUBJECTS
The study will be carried out in compliance with the protocol, the principles laid down in the 
Declaration of Helsinki, Guidelines for Good Pharmacoepidemiology Practice (GPP), and the 
relevant BI Standard Operating Procedures (SOPs). Standard medical care (prophylactic, 
diagnostic and therapeutic procedures) remains the responsibility of the treating physician of 
the patient.
STUDY APPROVAL, PATIENT INFORMATION, AND INFORMED 
CONSENT
This NIS will be initiated only after all required legal documentation has been reviewed and 
approved by the respective Institutional Review Board (IRB)/Independent Ethics Committee 
(IEC) and Competent Authority (CA) according to national and international regulations. The 
same applies for the implementation of changes introduced by amendments.
Prior to patient participation in the study, written informed consent must be obtained from 
each patient (or the patient’s legally accepted representative) per GPP and according to the 
regulatory and legal requirements of the participating country, if applicable. 
STATEMENT OF CONFIDENTIALITY
No patient’s identity or medical records will be disclosed for the purposes of this study 
except in compliance with applicable law. 

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11.
MANAGEMENT AND REPORTING OF ADVERSE 
EVENTS/ADVERSE REACTIONS
ADVERSE EVENT AND SERIOUS ADVERSE EVENT COLLECTION 
AND REPORTING
Collection of AEs
Not applicable based on secondary use of data without any potential that any employee of BI 
or agent working on behalf of BI will access individually identifiable patient data.

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12.
PLANS FOR DISSEMINATING AND COMMUNICATING 
STUDY RESULTS
The rights of the investigator and of the sponsor with regard to publication of the results of 
this study are described in the investigator contract. As a general rule, no study results should 
be published prior to finalization of the Study Report.

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13.
REFERENCES
PUBLISHED REFERENCES
P20-06571 
Palli SR, Frazer M, DuCharme M, Buikema AR, Anderson AJ, Franchino-
Elder J. Differences in Real-World Health and Economic Outcomes Among Patients with 
COPD Treated with Combination Tiotropium/Olodaterol Versus Triple Therapy. J Manag 
Care Spec Pharm. 2020;26(10):1363-1374.
R18-1532
Lipson DA, Barnhart F, Brealey N, et al. Once-Daily Single-Inhaler Triple 
versus Dual Therapy in Patients with COPD. N Engl J Med. 2018;378(18):1671-1680. 
R21-4089
Lipson DA, Crim C, Criner GJ, et al. Reduction in All-Cause Mortality with 
Fluticasone Furoate/Umeclidinium/Vilanterol in Patients with Chronic Obstructive 
Pulmonary Disease. Am J Respir Crit Care Med. 2020;201(12):1508-1516. 
R21-4088
Bogart MR, Hopson SD, Shih HC, Stanford RH, Coutinho AD. COPD 
exacerbation costs in the IMPACT study: a within-trial analysis. Am J Manag Care. 
2020;26(5):e150-e154. 
R12-1912
Rosenbaum PR, Rubin DB. The central role of the propensity score in 
observational studies for casual effects. Biometrika. 1983;70(1):41-55. 
R21-4317
U.S. Department of Labor BoLS. Consumer Price Index. Medical Care. Series 
ID: CUUR0000SAM.  http://data.bls.gov/cgi-bin/surveymost?cu.
P21-11033 
Frytak JR, Henk HJ, Zhao Y, Bowman L, Flynn JA, Nelson M. Health service 
utilization among Alzheimer's disease patients: evidence from managed care. Alzheimers 
Dement. 2008;4(5):361-367. 
R21-4119
2017 Condition-Specific Measures Updates and Specifications Report 
Hospital-Level 30-Day Risk-Standardized Readmission Measures. Yale New Haven Health 
Services Corporation/Center for Outcomes Research & Evaluation (YNHHSC/CORE).
R21-4087
Bayliss EA, Ellis JL, Shoup JA, Zeng C, McQuillan DB, Steiner JF. 
Association of patient-centered outcomes with patient-reported and ICD-9-based morbidity 
measures. Ann Fam Med. 2012;10(2):126-133.
R20-2288
Quan H, Li B, Couris CM, et al. Updating and validating the Charlson 
comorbidity index and score for risk adjustment in hospital discharge abstracts using data 
from 6 countries. Am J Epidemiol. 2011;173(6):676-682. 
R14-4775
Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining 
comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005;43(11):1130-
1139. 

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R13-3591
Elixhauser A, Steiner C, Harris DR, Coffey RM. Comorbidity measures for 
use with administrative data. Med Care. 1998;36(1):8-27. 
R21-4090
van Walraven C, Austin PC, Jennings A, Quan H, Forster AJ. A modification 
of the Elixhauser comorbidity measures into a point system for hospital death using 
administrative data. Med Care. 2009;47(6):626-633. 
R21-4086
Wu EQ, Birnbaum HG, Cifaldi M, Kang Y, Mallet D, Colice G. Development 
of a COPD severity score. Curr Med Res Opin. 2006;22(9):1679-1687. 
R21-4295
Health Resources & Services Administration. Data Downloads. Shortage 
Areas.  https://data.hrsa.gov/data/download. Accessed February 02, 2021.

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ANNEX 1. LIST OF STAND-ALONE DOCUMENTS
None

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ANNEX 2. ENCEPP CHECKLIST FOR STUDY PROTOCOLS
NA

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ANNEX 3. ADDITIONAL INFORMATION
Table 1. COPD-related Respiratory Medications and Classes
Drug Class
Subclass
Medication
Maintenance 
medications
Inhaled long-acting anti-
muscarinic 
agents (LAMA)
aclidinium
glycopyrrolate 
revefenacin
tiotropium
umeclidinium
Long-acting β-agonists 
(LABA)
arformoterol  
formoterol 
indacaterol 
olodaterol 
salmeterol
Inhaled corticosteroids (ICS)
beclomethasone
budesonide (both inhaler and nebulizer)
ciclensonide
flunisolide
fluticasone
mometasone
triamcinolone
Inhaled LAMA/LABA 
combination
aclidinium/formoterol
glycopyrrolate/formoterol 
indacaterol/glycopyrrolate 
tiotropium/olodaterol 
umeclidinium/vilanterol
Inhaled ICS/LABA 
combination
budesonide/formoterol
fluticasone/salmeterol
fluticasone/vilanterol
mometasone/formoterol
Inhaled ICS/LABA/LAMA 
Budesonide/glycopyrrolate/formoterol 

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Drug Class
Subclass
Medication
combination
fumarate1
Fluticasone/umeclidinium/vilanterol
Methylxanthines 
(intravenous, oral)
aminophylline
dyphylline
theophylline
PDE-4 inhibitor (oral)
roflumilast
Rescue
medications
Short-acting β-agonists 
(SABA) (inhalation, oral)
albuterol
bitolterol
isoetharine
isoproterenol
levalbuterol 
metaproterenol
pirbuterol
Short-acting anti-muscarinic 
Agents (SAMA) (inhalation)
ipratropium
SAMA/SABA (inhalation)
ipratropium/albuterol
Oral corticosteroids (OCS)2
betamethasone
dexamethasone
hydrocortisone
methylprednisolone
prednisolone
prednisone
1This medication was FDA approved for maintenance treatment of COPD on 24 July 2020, 
which is outside of the study time period, and will not be included in this study. 
2Including tablets, oral solutions, elixirs, etc. Injectable corticosteroid medications will not 
be included.

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COPD Guideline-recommend Antibiotic Medications
Drug Category
Drug Class
Medication
COPD Guideline-
recommended Antibiotics1
Cephalosporins
cefaclor
cefdinir
cefditoren
cefepime 
cefpodoxime 
cefprozil
ceftibuten
ceftriaxone 
cefuroxime 
Macrolides
azithromycin
clarithromycin
Penicillins
amoxicillin
amoxicillin/potassium 
piperacillin/tazobactam
Quinolones
levofloxacin
moxifloxacin
Sulfonamide 
combinations
sulfamethoxazole/trimethoprim
Tetracyclines
doxycycline

1The American Thoracic Society (2017) and Global Initiative for Chronic 
Obstructive Lung Disease (2020) guidelines recommend that antibiotics for acute 
exacerbation of chronic bronchitis be selected based on local sensitivity patterns. 
For more specific recommendations, The Sanford Guide to Antimicrobial Therapy 
(2020) was referenced. 
COPD Exacerbation Definition

Exacerbation Hierarchy: Exacerbation events will be classified as severe or 
moderate according to the highest severity contributing event. 

Exacerbation Episodes: Exacerbations occurring within 14 days of each other will 
be considered a single exacerbation episode and will be classified according to the 
highest severity contributing event. 

Episode Length: The start date of the exacerbation episode will be the service date of 
the first event (medical encounter or pharmacy fill for an OCS or antibiotic). The end 
date of the exacerbation episode will be defined as the last observed exacerbation 
event date (or discharge date if an inpatient event) + 14 days.  

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Single Event Episode

In a single event episode, the exacerbation begins with the earliest occurrence of these 
events: COPD exacerbation defined inpatient admission, ER visit, ambulatory visit, or 
corticosteroid or antibiotic dispensing as defined in Section 9.3.2.1. In a single event 
episode, the exacerbation ends 14 days from the start of the event, hospital discharge, 
or following the OCS or antibiotic dispensing, whichever is later.
Episode Start date = service date of a qualifying event (inpatient admission, ED visit, 
ambulatory visit, or OCS or antibiotic dispensing).  

If the qualifying event is a hospitalization, the start date is the admission date.  

If the qualifying event is an ED visit, the start date is the service date.  

If the qualifying event is an ambulatory visit or an OCS or antibiotic dispensing, the 
start date is the earliest of the associated medical visit or medication dispensing date. 
Episode End Date

If the qualifying event is a hospitalization: discharge date + 14 days 

If the qualifying event is an ER visit: start date + 14 days 

If the qualifying event is an ambulatory visit or an OCS or antibiotic dispensing: the 
latest of the medical visit or medication dispensing + 14 days

If the Episode End Date is after the end of follow-up, then set an additional flag 
CENSORED=1. 

NOTE: Under this definition, it is possible for the runout of a medication to exceed 
the End Date. 
MULTIPLE EVENT EPISODES
If another qualifying event occurs before the episode End Date, then the episode is extended. 
The date of the second event is used to reset the End Date per the definition above, using 
information from this second event. The process continues until a 14-day period with no 
exacerbation qualifying events occur. The End Date is set (as defined above).  

Episode Length: (End date – Start date) + 1

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Condition
Code
Code 
type
Description
COPD
491.0
ICD-9 
Dx
Simple chronic bronchitis
491.1
ICD-9 
Dx
Mucopurulent chronic bronchitis
491.20
ICD-9 
Dx
Obstructive chronic bronchitis, without 
exacerbation
491.21
ICD-9 
Dx
Obstructive chronic bronchitis, with (acute) 
exacerbation
491.22
ICD-9 
Dx
Obstructive chronic bronchitis with acute bronchitis
491.8
ICD-9 
Dx
Other chronic bronchitis
491.9
ICD-9 
Dx
Unspecified chronic bronchitis
492.0
ICD-9 
Dx
Emphysematous bleb
492.8
ICD-9 
Dx
Other emphysema
496
ICD-9 
Dx
Chronic airway obstruction, not elsewhere classified
J41.0
ICD-10 
Dx
Simple chronic bronchitis
J41.1
ICD-10 
Dx
Mucopurulent chronic bronchitis
J41.8
ICD-10 
Dx
Mixed simple and mucopurulent chronic bronchitis
J42
ICD-10 
Dx
Unspecified chronic bronchitis
J43.0
ICD-10 
Dx
Unilateral pulmonary emphysema (MacLeod’s 
syndrome)
J43.1
ICD-10 
Dx
Panlobular emphysema
J43.2
ICD-10 
Dx
Centrilobular emphysema

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J43.8
ICD-10 
Dx
Other emphysema
J43.9
ICD-10 
Dx
Emphysema, unspecified
J44.0
ICD-10 
Dx
Chronic obstructive pulmonary disease with acute 
lower respiratory infection
J44.1
ICD-10 
Dx
Chronic obstructive pulmonary disease with (acute) 
exacerbation
J44.9
ICD-10 
Dx
Chronic obstructive pulmonary disease, unspecified
Asthma
493
ICD-9 
Dx
Asthma
493.00
ICD-9 
Dx
Extrinsic asthma, unspecified
493.01
ICD-9 
Dx
Extrinsic asthma with status asthmaticus
493.02
ICD-9 
Dx
Extrinsic asthma, with (acute) exacerbation
493.10
ICD-9 
Dx
Intrinsic asthma, unspecified
493.11
ICD-9 
Dx
Intrinsic asthma with status asthmaticus
493.12
ICD-9 
Dx
Intrinsic asthma, with (acute) exacerbation
493.20
ICD-9 
Dx
Chronic obstructive asthma, unspecified 
493.21
ICD-9 
Dx
Chronic obstructive asthma with status asthmaticus
493.22
ICD-9 
Dx
Chronic obstructive asthma, with (acute) 
exacerbation 
493.81
ICD-9 
Dx
Exercise induced bronchospasm
493.82
ICD-9 
Dx
Cough variant asthma
493.90
ICD-9 
Dx
Asthma, unspecified, unspecified status

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493.91
ICD-9 
Dx
Asthma, unspecified with status asthmaticus
493.92
ICD-9 
Dx
Asthma, unspecified, with (acute) exacerbation
J45
ICD-10 
Dx
Asthma
J4520
ICD-10 
Dx
Mild intermittent asthma, uncomplicated
J4521
ICD-10 
Dx
Mild intermittent asthma with (acute) exacerbation
J4522
ICD-10 
Dx
Mild intermittent asthma with status asthmaticus
J4530
ICD-10 
Dx
Mild persistent asthma, uncomplicated
J4531
ICD-10 
Dx
Mild persistent asthma with (acute) exacerbation
J4532
ICD-10 
Dx
Mild persistent asthma with status asthmaticus
J4540
ICD-10 
Dx
Moderate persistent asthma, uncomplicated
J4541
ICD-10 
Dx
Moderate persistent asthma with (acute) 
exacerbation
J4542
ICD-10 
Dx
Moderate persistent asthma with status asthmaticus
J4550
ICD-10 
Dx
Severe persistent asthma, uncomplicated
J4551
ICD-10 
Dx
Severe persistent asthma with (acute) exacerbation
J4552
ICD-10 
Dx
Severe persistent asthma with status asthmaticus
J45901
ICD-10 
Dx
Unspecified asthma with (acute) exacerbation
J45902
ICD-10 
Dx
Unspecified asthma with status asthmaticus
J45909
ICD-10 
Dx
Unspecified asthma, uncomplicated

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J45990
ICD-10 
Dx
Exercise induced bronchospasm
J45991
ICD-10 
Dx
Cough variant asthma
J45998
ICD-10 
Dx
Other asthma
Cystic 
Fibrosis
277.0
ICD-9 
Dx
Cystic fibrosis
277.00
ICD-9 
Dx
Cystic fibrosis without mention of meconium ileus
277.01
ICD-9 
Dx
Cystic fibrosis with meconium ileus
277.02
ICD-9 
Dx
Cystic fibrosis with pulmonary manifestations
277.03
ICD-9 
Dx
Cystic fibrosis with gastrointestinal manifestations
277.09
ICD-9 
Dx
Cystic fibrosis with other manifestations
E84
ICD-10 
Dx
Cystic fibrosis
E84.0
ICD-10 
Dx
Cystic fibrosis with pulmonary manifestations
E84.11
ICD-10 
Dx
Meconium ileus in cystic fibrosis
E84.19
ICD-10 
Dx
Cystic fibrosis with other intestinal manifestations
E84.8
ICD-10 
Dx
Cystic fibrosis with other manifestations
E84.9
ICD-10 
Dx
Cystic fibrosis, unspecified
Lung 
Cancer
162.2
ICD-9 
Dx
Malignant neoplasm of main bronchus
162.3
ICD-9 
Dx
Malignant neoplasm of upper lobe, bronchus or 
lung
162.4
ICD-9 
Dx
Malignant neoplasm of middle lobe, bronchus or 
lung

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162.5
ICD-9 
Dx
Malignant neoplasm of lower lobe, bronchus or 
lung
162.8
ICD-9 
Dx
Malignant neoplasm of other parts of bronchus or 
lung
162.9
ICD-9 
Dx
Malignant neoplasm of bronchus and lung, 
unspecified
C34
ICD-10 
Dx
Malignant neoplasm of bronchus and lung
C340
ICD-10 
Dx
Malignant neoplasm of main bronchus 
C3400
ICD-10 
Dx
Malignant neoplasm of unspecified main bronchus 
C3401
ICD-10 
Dx
Malignant neoplasm of right main bronchus 
C3402
ICD-10 
Dx
Malignant neoplasm of left main bronchus 
C341
ICD-10 
Dx
Malignant neoplasm of upper lobe, bronchus or lung 
C3410
ICD-10 
Dx
Malignant neoplasm of upper lobe, unspecified 
bronchus or lung
C3411
ICD-10 
Dx
Malignant neoplasm of upper lobe, right bronchus 
or lung 
C3412
ICD-10 
Dx
Malignant neoplasm of upper lobe, left bronchus or 
lung
C342
ICD-10 
Dx
Malignant neoplasm of middle lobe, bronchus or 
lung 
C343
ICD-10 
Dx
Malignant neoplasm of lower lobe, bronchus or lung 
C3430
ICD-10 
Dx
Malignant neoplasm of lower lobe, unspecified 
bronchus or lung 
C3431
ICD-10 
Dx
Malignant neoplasm of lower lobe, right bronchus 
or lung 
C3432
ICD-10 
Dx
Malignant neoplasm of lower lobe, left bronchus or 
lung 
C348
ICD-10 
Dx
Malignant neoplasm of overlapping sites of 
bronchus and lung 

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C3480
ICD-10 
Dx
Malignant neoplasm of overlapping sites of 
unspecified bronchus and lung 
C3481
ICD-10 
Dx
Malignant neoplasm of overlapping sites of right 
bronchus and lung 
C3482
ICD-10 
Dx
Malignant neoplasm of overlapping sites of left 
bronchus and lung 
C349
ICD-10 
Dx
Malignant neoplasm of unspecified part of bronchus 
or lung 
C3490
ICD-10 
Dx
Malignant neoplasm of unspecified part of 
unspecified bronchus or lung 
C3491
ICD-10 
Dx
Malignant neoplasm of unspecified part of right 
bronchus or lung 
C3492
ICD-10 
Dx
Malignant neoplasm of unspecified part of left 
bronchus or lung 
Interstitial 
Lung 
Disease
515
ICD-9 
Dx
Post-inflammatory pulmonary fibrosis
516.3
ICD-9 
Dx
Idiopathic fibrosing alveolitis
516.8
ICD-9 
Dx
Other specified alveolar and parietoalveolar 
pneumopathies (Interstitial Pneumonia, DIP, LIP)
516.9
ICD-9 
Dx
Unspecified alveolar and parietoalveolar 
pneumopathy
517.1
ICD-9 
Dx
Rheumatic pneumonia
517.2
ICD-9 
Dx
Lung involvement in systemic sclerosis
517.8
ICD-9 
Dx
Lung involvement in other diseases classified 
elsewhere (autoimmune, sarcoid)
714.81
ICD-9 
Dx
Rheumatoid Lung
J84
ICD-10 
Dx
Other interstitial pulmonary diseases
J84.1
ICD-10 
Dx
Pulmonary fibrosis, unspecified
J84.8
ICD-10 
Dx
Other specified interstitial pulmonary diseases

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J84.9
ICD-10 
Dx
Interstitial pulmonary disease, unspecified
J84.09
ICD-10 
Dx
Other alveolar and parieto-alveolar conditions
Lung 
volume 
reduction 
procedure
32480
CPT
Removal of lung, other than pneumonectomy; 
single lobe (lobectomy)
32482
CPT
Removal of lung, other than pneumonectomy; 2 
lobes (bilobectomy)
32484
CPT
Removal of lung, other than pneumonectomy; 
single segment (segmentectomy)
32486
CPT
Removal of lung, other than pneumonectomy; with 
circumferential resection of segment of bronchus 
followed by broncho-bronchial anastomosis (sleeve 
lobectomy)
32491
CPT
Removal of lung, other than pneumonectomy; with 
resection-plication of emphysematous lung(s) 
(bullous or non-bullous) for lung volume reduction, 
sternal split or transthoracic approach, includes any 
pleural procedure, when performed
32669
CPT
Thoracoscopy, surgical; with removal of a single 
lung segment (segmentectomy)
32672
CPT
Thoracoscopy, surgical; with resection-plication for 
emphysematous lung (bullous or non-bullous) for 
lung volume reduction (LVRS), unilateral includes 
any pleural procedure, when performed
Pneumoni
a
480.1
ICD-9 
Dx
Pneumonia due to respiratory syncytial virus
480.2
ICD-9 
Dx
Pneumonia due to parainfluenza virus
480.3
ICD-9
Dx
Pneumonia due to SARS-associated coronavirus
480.8
ICD-9 
Dx
Pneumonia due to other virus not elsewhere 
classified
480.9
ICD-9 
Dx
Unspecified viral pneumonia
481
ICD-9 
Dx
Pneumococcal pneumonia (streptococcus 
pneumoniae pneumonia)

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482.1
ICD-9 
Dx
Pneumonia due to Pseudomonas
482.2
ICD-9 
Dx
Pneumonia due to Hemophilus influenzae (H. 
influenzae)
482.31
ICD-9 
Dx
Pneumonia due to Streptococcus, group A
482.32
ICD-9 
Dx
Pneumonia due to Streptococcus, group B
482.39
ICD-9 
Dx
Pneumonia due to other Streptococcus
482.41
ICD-9 
Dx
Methicillin susceptible pneumonia due to 
Staphylococcus aureus
482.42
ICD-9 
Dx
Methicillin resistant pneumonia due to 
Staphylococcus aureus
482.49
ICD-9 
Dx
Other Staphylococcus pneumonia
482.81
ICD-9 
Dx
Pneumonia due to anaerobes
482.82
ICD-9 
Dx
Pneumonia due to Escherichia coli (E. coli)
482.83
ICD-9 
Dx
Pneumonia due to other gram-negative bacteria
482.84
ICD-9 
Dx
Legionnaires' disease
482.89
ICD-9 
Dx
Pneumonia due to other specified bacteria
482.9
ICD-9 
Dx
Unspecified bacterial pneumonia
483.1
ICD-9 
Dx
Pneumonia due to Chlamydia
483.8
ICD-9 
Dx
Pneumonia due to other specified organism
484.1
ICD-9 
Dx
Pneumonia in cytomegalic inclusion disease
484.3
ICD-9 
Dx
Pneumonia in whooping cough

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484.6
ICD-9 
Dx
Pneumonia in aspergillosis
484.7
ICD-9 
Dx
Pneumonia in other systemic mycoses
484.8
ICD-9 
Dx
Pneumonia in other infectious diseases classified 
elsewhere
485
ICD-9 
Dx
Bronchopneumonia, organism unspecified
486
ICD-9 
Dx
Pneumonia, organism unspecified
003.22
ICD-9 
Dx
Salmonella pneumonia
011.60
ICD-9 
Dx
Tuberculous pneumonia (any form), confirmation 
unspecified
011.61
ICD-9 
Dx
Tuberculous pneumonia (any form), bacteriological 
or histological examination not done
011.62
ICD-9 
Dx
Tuberculous pneumonia (any form), bacteriological 
or histological examination unknown (at present)
011.63
ICD-9 
Dx
Tuberculous pneumonia (any form), tubercle bacilli 
found (in sputum) by microscopy
011.64
ICD-9 
Dx
Tuberculous pneumonia (any form), tubercle bacilli 
not found (in sputum) by microscopy, but found by 
bacterial culture
011.65
ICD-9 
Dx
Tuberculous pneumonia (any form), tubercle bacilli 
not found by bacteriological examination, but 
tuberculosis confirmed histologically
011.66
ICD-9 
Dx
Tuberculous pneumonia (any form), tubercle bacilli 
not found by bacteriological or histological 
examination, but tuberculosis confirmed by other 
methods [inoculation of animals]
052.1
ICD-9 
Dx
Varicella (hemorrhagic) pneumonitis
055.1
ICD-9 
Dx
Postmeasles pneumonia
073.0
ICD-9 
Dx
Ornithosis with pneumonia
115.05
ICD-9 
Dx
Histoplasma capsulatum pneumonia

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115.15
ICD-9 
Dx
Histoplasma duboisii pneumonia
115.95
ICD-9 
Dx
Unspecified Histoplasmosis pneumonia
130.4
ICD-9 
Dx
Pneumonitis due to toxoplasmosis
480.0
ICD-9 
Dx
Pneumonia due to adenovirus
482.0
ICD-9 
Dx
Pneumonia due to Klebsiella pneumoniae
482.30
ICD-9 
Dx
Pneumonia due to unspecified Streptococcus
482.40
ICD-9 
Dx
Pneumonia due to Staphylococcus, unspecified
483.0
ICD-9 
Dx
Pneumonia due to Mycoplasma pneumoniae
487.0
ICD-9 
Dx
Influenza with pneumonia
488.01
ICD-9 
Dx
Influenza due to identified avian influenza virus 
with pneumonia
488.11
ICD-9 
Dx
Influenza due to identified 2009 H1N1 influenza 
virus with pneumonia
488.81
ICD-9 
Dx
Influenza due to identified novel influenza A virus 
with pneumonia
495.7
ICD-9 
Dx
Ventilation pneumonitis
495.8
ICD-9 
Dx
Other specified allergic alveolitis and pneumonitis
495.9
ICD-9 
Dx
Unspecified allergic alveolitis and pneumonitis
506.0
ICD-9 
Dx
Bronchitis and pneumonitis due to fumes and 
vapors
507.0
ICD-9 
Dx
Pneumonitis due to inhalation of food or vomitus
507.1
ICD-9 
Dx
Pneumonitis due to inhalation of oils and essences

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507.8
ICD-9 
Dx
Pneumonitis due to other solids and liquids
516.30
ICD-9 
Dx
Idiopathic interstitial pneumonia, not otherwise 
specified
516.32
ICD-9 
Dx
Idiopathic non-specific interstitial pneumonitis
516.33
ICD-9 
Dx
Acute interstitial pneumonitis
516.35
ICD-9 
Dx
Idiopathic lymphoid interstitial pneumonia
516.36
ICD-9 
Dx
Cryptogenic organizing pneumonia
516.37
ICD-9 
Dx
Desquamative interstitial pneumonia
517.1
ICD-9 
Dx
Rheumatic pneumonia
997.31
ICD-9 
Dx
Ventilator associated pneumonia
997.32
ICD-9 
Dx
Postprocedural aspiration pneumonia
A0103
ICD-10 
Dx
Typhoid pneumonia
A0222
ICD-10 
Dx
Salmonella pneumonia
A3701
ICD-10 
Dx
Whooping cough due to Bordetella pertussis with 
pneumonia
A3711
ICD-10 
Dx
Whooping cough due to Bordetella parapertussis 
with pneumonia
A3781
ICD-10 
Dx
Whooping cough due to other Bordetella species 
with pneumonia
A3791
ICD-10 
Dx
Whooping cough, unspecified species with 
pneumonia
A481
ICD-10 
Dx
Legionnaires' disease
A5484
ICD-10 
Dx
Gonococcal pneumonia

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B012
ICD-10 
Dx
Varicella pneumonia
B052
ICD-10 
Dx
Measles complicated by pneumonia
B0681
ICD-10 
Dx
Rubella pneumonia
B250
ICD-10 
Dx
Cytomegaloviral pneumonitis
B440
ICD-10 
Dx
Invasive pulmonary aspergillosis
J09X1
ICD-10 
Dx
Influenza due to identified novel influenza A virus 
with pneumonia
J1000
ICD-10 
Dx
Influenza due to other identified influenza virus 
with unspecified type of pneumonia
J1001
ICD-10 
Dx
Influenza due to other identified influenza virus 
with the same other identified influenza virus 
pneumonia
J1008
ICD-10 
Dx
Influenza due to other identified influenza virus 
with other specified pneumonia
J1100
ICD-10 
Dx
Influenza due to unidentified influenza virus with 
unspecified type of pneumonia
J1108
ICD-10 
Dx
Influenza due to unidentified influenza virus with 
specified pneumonia
J120
ICD-10 
Dx
Adenoviral pneumonia
J121
ICD-10 
Dx
Respiratory syncytial virus pneumonia
J122
ICD-10 
Dx
Parainfluenza virus pneumonia
J123
ICD-10 
Dx
Human metapneumovirus pneumonia
J1281
ICD-10 
Dx
Pneumonia due to SARS-associated coronavirus
J1289
ICD-10 
Dx
Other viral pneumonia
J129
ICD-10 
Dx
Viral pneumonia, unspecified

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J13
ICD-10 
Dx
Pneumonia due to Streptococcus pneumoniae
J14
ICD-10 
Dx
Pneumonia due to Hemophilus influenzae
J150
ICD-10 
Dx
Pneumonia due to Klebsiella pneumoniae
J151
ICD-10 
Dx
Pneumonia due to Pseudomonas
J1520
ICD-10 
Dx
Pneumonia due to staphylococcus, unspecified
J15211
ICD-10 
Dx
Pneumonia due to Methicillin susceptible 
Staphylococcus aureus
J15212
ICD-10 
Dx
Pneumonia due to Methicillin resistant 
Staphylococcus aureus
J1529
ICD-10 
Dx
Pneumonia due to other staphylococcus
J153
ICD-10 
Dx
Pneumonia due to streptococcus, group B
J154
ICD-10 
Dx
Pneumonia due to other streptococci
J155
ICD-10 
Dx
Pneumonia due to Escherichia coli
J156
ICD-10 
Dx
Pneumonia due to other aerobic Gram-negative 
bacteria
J157
ICD-10 
Dx
Pneumonia due to Mycoplasma pneumoniae
J158
ICD-10 
Dx
Pneumonia due to other specified bacteria
J159
ICD-10 
Dx
Unspecified bacterial pneumonia
J160
ICD-10 
Dx
Chlamydial pneumonia
J168
ICD-10 
Dx
Pneumonia due to other specified infectious 
organisms
J17
ICD-10 
Dx
Pneumonia in diseases classified elsewhere

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2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
J180
ICD-10 
Dx
Bronchopneumonia, unspecified organism
J181
ICD-10 
Dx
Lobar pneumonia, unspecified organism
J182
ICD-10 
Dx
Hypostatic pneumonia, unspecified organism
J188
ICD-10 
Dx
Other pneumonia, unspecified organism
J189
ICD-10 
Dx
Pneumonia, unspecified organism
J200
ICD-10 
Dx
Acute bronchitis due to Mycoplasma pneumoniae
J678
ICD-10 
Dx
Hypersensitivity pneumonitis due to other organic 
dusts
J679
ICD-10 
Dx
Hypersensitivity pneumonitis due to unspecified 
organic dust
J680
ICD-10 
Dx
Bronchitis and pneumonitis due to chemicals, gases, 
fumes and vapors
J690
ICD-10 
Dx
Pneumonitis due to inhalation of food and vomit
J691
ICD-10 
Dx
Pneumonitis due to inhalation of oils and essences
J698
ICD-10 
Dx
Pneumonitis due to inhalation of other solids and 
liquids
J84111
ICD-10 
Dx
Idiopathic interstitial pneumonia, not otherwise 
specified
J84113
ICD-10 
Dx
Idiopathic non-specific interstitial pneumonitis
J84114
ICD-10 
Dx
Acute interstitial pneumonitis
J84116
ICD-10 
Dx
Cryptogenic organizing pneumonia
J84117
ICD-10 
Dx
Desquamative interstitial pneumonia
J842
ICD-10 
Dx
Lymphoid interstitial pneumonia

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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
J851
ICD-10 
Dx
Abscess of lung with pneumonia
J954
ICD-10 
Dx
Chemical pneumonitis due to anesthesia
J95851
ICD-10 
Dx
Ventilator associated pneumonia
Bronchitis
/bronchiol
itis
466
ICD-9 
Dx
Acute bronchitis and bronchiolitis
466.0
ICD-9 
Dx
Acute bronchitis
466.1
ICD-9 
Dx
Acute bronchiolitis
466.11
ICD-9 
Dx
Acute bronchiolitis due to respiratory syncytial 
virus (RSV) 
466.19
ICD-9 
Dx
Acute bronchiolitis due to other infectious 
organisms 
J20
ICD-10 
Dx
Acute bronchitis
J200
ICD-10 
Dx
Acute bronchitis due to Mycoplasma pneumoniae 
J201
ICD-10 
Dx
Acute bronchitis due to Hemophilus influenzae 
J202
ICD-10 
Dx
Acute bronchitis due to streptococcus
J203
ICD-10 
Dx
Acute bronchitis due to coxsackievirus 
J204
ICD-10 
Dx
Acute bronchitis due to parainfluenza virus 
J205
ICD-10 
Dx
Acute bronchitis due to respiratory syncytial virus 
J206
ICD-10 
Dx
Acute bronchitis due to rhinovirus
J207
ICD-10 
Dx
Acute bronchitis due to echovirus 
J208
ICD-10 
Dx
Acute bronchitis due to other specified organisms

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2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
J209
ICD-10 
Dx
Acute bronchitis, unspecified 
J21
ICD-10 
Dx
Acute bronchiolitis
J210
ICD-10 
Dx
Acute bronchiolitis due to respiratory syncytial 
virus 
J211
ICD-10 
Dx
Acute bronchiolitis due to human metapneumovirus 
J218
ICD-10 
Dx
Acute bronchiolitis due to other specified organisms 
J219
ICD-10 
Dx
Acute bronchiolitis, unspecified 
Acute 
respiratory 
failure
518.81
ICD-9 
Dx
Acute respiratory failure
518.82
ICD-9 
Dx
Other pulmonary insufficiency, not elsewhere 
classified
518.84
ICD-9 
Dx
Acute and chronic respiratory failure
799.1
ICD-9 
Dx
Respiratory arrest
J9600
ICD-10 
Dx
Acute respiratory failure, unspecified whether with 
hypoxia or hypercapnia
J9601
ICD-10 
Dx
Acute respiratory failure with hypoxia
J9602
ICD-10 
Dx
Acute respiratory failure with hypercapnia
J80
ICD-10 
Dx
Acute respiratory distress syndrome
J9620
ICD-10 
Dx
Acute and chronic respiratory failure, unspecified 
whether with hypoxia or hypercapnia
J9621
ICD-10 
Dx
Acute and chronic respiratory failure with hypoxia
J9622
ICD-10 
Dx
Acute and chronic respiratory failure with 
hypercapnia
R092
ICD-10 
Dx
Respiratory arrest

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2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
Acute 
exacerbati
on of 
COPD
491.21
ICD-9 
Dx
With (acute) exacerbation
491.22
ICD-9 
Dx
With acute bronchitis
493.21
ICD-9 
Dx
Chronic obstructive asthma with status asthmaticus
493.22
ICD-9 
Dx
Chronic obstructive asthma, with (acute) 
exacerbation
J441
ICD-10 
Dx
Chronic obstructive pulmonary disease with (acute) 
exacerbation
J440
ICD-10 
Dx
Chronic obstructive pulmonary disease with (acute) 
lower respiratory infection
Planned 
procedure
s and 
diagnoses
Z510
ICD-10 
Dx
Encounter for antineoplastic radiation therapy
Z5111
ICD-10 
Dx
Encounter for antineoplastic chemotherapy
Z5112
ICD-10 
Dx
Encounter for antineoplastic immunotherapy
Z44001
ICD-10 
Dx
Encounter for fit/adjst of unsp right artificial arm
Z44002
ICD-10 
Dx
Encounter for fit/adjst of unsp left artificial arm
Z44009
ICD-10 
Dx
Encounter for fit/adjst of unsp artificial arm, unsp 
arm
Z44011
ICD-10 
Dx
Encounter for fit/adjst of complete right artificial 
arm
Z44012
ICD-10 
Dx
Encounter for fit/adjst of complete left artificial arm
Z44019
ICD-10 
Dx
Encounter for fit/adjst of complete artificial arm, 
unsp arm
Z44021
ICD-10 
Dx
Encounter for fit/adjst of partial artificial right arm
Z44022
ICD-10 
Dx
Encounter for fit/adjst of partial artificial left arm
Z44029
ICD-10 
Dx
Encounter for fit/adjst of partial artificial arm, unsp 
arm

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2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
Z44101
ICD-10 
Dx
Encounter for fit/adjst of unsp right artificial leg
Z44102
ICD-10 
Dx
Encounter for fit/adjst of unsp left artificial leg
Z44109
ICD-10 
Dx
Encounter for fit/adjst of unsp artificial leg, unsp leg
Z44111
ICD-10 
Dx
Encounter for fit/adjst of complete right artificial 
leg
Z44112
ICD-10 
Dx
Encounter for fit/adjst of complete left artificial leg
Z44119
ICD-10 
Dx
Encounter for fit/adjst of complete artificial leg, 
unsp leg
Z44121
ICD-10 
Dx
Encounter for fit/adjst of partial artificial right leg
Z44122
ICD-10 
Dx
Encounter for fit/adjst of partial artificial left leg
Z44129
ICD-10 
Dx
Encounter for fit/adjst of partial artificial leg, unsp 
leg
Z4430
ICD-10 
Dx
Encntr for fit/adjst of external breast prosth, unsp 
breast
Z4431
ICD-10 
Dx
Encounter for fit/adjst of external right breast 
prosthesis
Z4432
ICD-10 
Dx
Encounter for fit/adjst of external left breast 
prosthesis
Z448
ICD-10 
Dx
Encounter for fit/adjst of external prosthetic devices
Z449
ICD-10 
Dx
Encounter for fit/adjst of unsp external prosthetic 
device
Z451
ICD-10 
Dx
Encounter for adjustment and management of 
infusion pump
Z4531
ICD-10 
Dx
Encntr for adjust and mgmt of implnt visual 
substitution dev
Z45320
ICD-10 
Dx
Encounter for adjust and mgmt of bone conduction 
device
Z45321
ICD-10 
Dx
Encounter for adjustment and management of 
cochlear device

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2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
Z45328
ICD-10 
Dx
Encounter for adjust and management of implanted 
hear dev
Z4541
ICD-10 
Dx
Encounter for adjustment and management of CSF 
drain dev
Z4542
ICD-10 
Dx
Encounter for adjust and mgmt of neuropacemaker 
(brain)
Z4549
ICD-10 
Dx
Encntr for adjust and mgmt of implanted nervous 
sys device
Z45811
ICD-10 
Dx
Encounter for adjustment or removal of right breast 
implant
Z45812
ICD-10 
Dx
Encounter for adjustment or removal of left breast 
implant
Z45819
ICD-10 
Dx
Encounter for adjustment or removal of unsp breast 
implant
Z4682
ICD-10 
Dx
Encounter for fit/adjst of non-vascular catheter
Z4689
ICD-10 
Dx
Encounter for fitting and adjustment of oth devices
Z469
ICD-10 
Dx
Encounter for fitting and adjustment of unspecified 
device
30230AZ
ICD-10 
Proc
Transfuse of Embr Stem Cell into Periph Vein, 
Open Approach
30230G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Periph Vein, Open
30230G1
ICD-10 
Proc
Transfusion of Nonautologous Bone Marrow into 
Peripheral Vei
30230G2
ICD-10 
Proc
Transfuse Allo Rel Bone Marrow in Periph Vein, 
Open
30230G3
ICD-10 
Proc
Transfuse Allo Unr Bone Marrow in Periph Vein, 
Open
30230G4
ICD-10 
Proc
Transfuse Allo Unsp Bone Marrow in Periph Vein, 
Open
30230X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Periph Vein, 
Open
30230X1
ICD-10 
Proc
Transfusion of Nonautologous Cord Blood Stem 
Cells into Peri

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
30230X2
ICD-10 
Proc
Transfuse Allo Rel Cord Bld Stem Cell in Periph 
Vein, Open
30230X3
ICD-10 
Proc
Transfuse Allo Unr Cord Bld Stem Cell in Periph 
Vein, Open
30230X4
ICD-10 
Proc
Transfuse Allo Unsp Cord Bld Stem Cell in Periph 
Vein, Open
30230Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Periph Vein, 
Open
30230Y1
ICD-10 
Proc
Transfusion of Nonautologous Hematopoietic Stem 
Cells into P
30230Y2
ICD-10 
Proc
Transfuse Allo Rel Hemat Stem Cell in Periph 
Vein, Open
30230Y3
ICD-10 
Proc
Transfuse Allo Unr Hemat Stem Cell in Periph 
Vein, Open
30230Y4
ICD-10 
Proc
Transfuse Allo Unsp Hemat Stem Cell in Periph 
Vein, Open
30233AZ
ICD-10 
Proc
Transfuse of Embr Stem Cell into Periph Vein, Perc 
Approach
30233G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Periph Vein, Perc
30233G1
ICD-10 
Proc
Transfusion of Nonautologous Bone Marrow into 
Peripheral Vei
30233G2
ICD-10 
Proc
Transfuse Allo Rel Bone Marrow in Periph Vein, 
Perc
30233G3
ICD-10 
Proc
Transfuse Allo Unr Bone Marrow in Periph Vein, 
Perc
30233G4
ICD-10 
Proc
Transfuse Allo Unsp Bone Marrow in Periph Vein, 
Perc
30233X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Periph Vein, 
Perc
30233X1
ICD-10 
Proc
Transfusion of Nonautologous Cord Blood Stem 
Cells into Peri
30233X2
ICD-10 
Proc
Transfuse Allo Rel Cord Bld Stem Cell in Periph 
Vein, Perc
30233X3
ICD-10 
Proc
Transfuse Allo Unr Cord Bld Stem Cell in Periph 
Vein, Perc

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
30233X4
ICD-10 
Proc
Transfuse Allo Unsp Cord Bld Stem Cell in Periph 
Vein, Perc
30233Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Periph Vein, 
Perc
30233Y1
ICD-10 
Proc
Transfusion of Nonautologous Hematopoietic Stem 
Cells into P
30233Y2
ICD-10 
Proc
Transfuse Allo Rel Hemat Stem Cell in Periph 
Vein, Perc
30233Y3
ICD-10 
Proc
Transfuse Allo Unr Hemat Stem Cell in Periph 
Vein, Perc
30233Y4
ICD-10 
Proc
Transfuse Allo Unsp Hemat Stem Cell in Periph 
Vein, Perc
30240AZ
ICD-10 
Proc
Transfuse of Embr Stem Cell into Central Vein, 
Open Approach
30240G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Central Vein, 
Open
30240G1
ICD-10 
Proc
Transfusion of Nonautologous Bone Marrow into 
Central Vein O
30240G2
ICD-10 
Proc
Transfuse Allo Rel Bone Marrow in Central Vein, 
Open
30240G3
ICD-10 
Proc
Transfuse Allo Unr Bone Marrow in Central Vein, 
Open
30240G4
ICD-10 
Proc
Transfuse Allo Unsp Bone Marrow in Central Vein, 
Open
30240X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Central 
Vein, Open
30240X1
ICD-10 
Proc
Transfusion of Nonautologous Cord Blood Stem 
Cells into Cent
30240X2
ICD-10 
Proc
Transfuse Allo Rel Cord Bld Stem Cell in Central 
Vein, Open
30240X3
ICD-10 
Proc
Transfuse Allo Unr Cord Bld Stem Cell in Central 
Vein, Open
30240X4
ICD-10 
Proc
Transfuse Allo Unsp Cord Bld Stem Cell in Central 
Vein, Open
30240Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Central Vein, 
Open

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2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
30240Y1
ICD-10 
Proc
Transfusion of Nonautologous Hematopoietic Stem 
Cells into C
30240Y2
ICD-10 
Proc
Transfuse Allo Rel Hemat Stem Cell in Central 
Vein, Open
30240Y3
ICD-10 
Proc
Transfuse Allo Unr Hemat Stem Cell in Central 
Vein, Open
30240Y4
ICD-10 
Proc
Transfuse Allo Unsp Hemat Stem Cell in Central 
Vein, Open
30243AZ
ICD-10 
Proc
Transfuse of Embr Stem Cell into Central Vein, 
Perc Approach
30243G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Central Vein, Perc
30243G1
ICD-10 
Proc
Transfusion of Nonautologous Bone Marrow into 
Central Vein P
30243G2
ICD-10 
Proc
Transfuse Allo Rel Bone Marrow in Central Vein, 
Perc
30243G3
ICD-10 
Proc
Transfuse Allo Unr Bone Marrow in Central Vein, 
Perc
30243G4
ICD-10 
Proc
Transfuse Allo Unsp Bone Marrow in Central Vein, 
Perc
30243X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Central 
Vein, Perc
30243X1
ICD-10 
Proc
Transfusion of Nonautologous Cord Blood Stem 
Cells into Cent
30243X2
ICD-10 
Proc
Transfuse Allo Rel Cord Bld Stem Cell in Central 
Vein, Perc
30243X3
ICD-10 
Proc
Transfuse Allo Unr Cord Bld Stem Cell in Central 
Vein, Perc
30243X4
ICD-10 
Proc
Transfuse Allo Unsp Cord Bld Stem Cell in Central 
Vein, Perc
30243Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Central Vein, 
Perc
30243Y1
ICD-10 
Proc
Transfusion of Nonautologous Hematopoietic Stem 
Cells into C
30243Y2
ICD-10 
Proc
Transfuse Allo Rel Hemat Stem Cell in Central 
Vein, Perc

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30243Y3
ICD-10 
Proc
Transfuse Allo Unr Hemat Stem Cell in Central 
Vein, Perc
30243Y4
ICD-10 
Proc
Transfuse Allo Unsp Hemat Stem Cell in Central 
Vein, Perc
30250G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Periph Art, Open
30250G1
ICD-10 
Proc
Transfuse Nonaut Bone Marrow in Periph Art, 
Open
30250X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Periph Art, 
Open
30250X1
ICD-10 
Proc
Transfuse Nonaut Cord Bld Stem Cell in Periph Art, 
Open
30250Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Periph Art, 
Open
30250Y1
ICD-10 
Proc
Transfuse Nonaut Hemat Stem Cell in Periph Art, 
Open
30253G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Periph Art, Perc
30253G1
ICD-10 
Proc
Transfuse Nonaut Bone Marrow in Periph Art, Perc
30253X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Periph Art, 
Perc
30253X1
ICD-10 
Proc
Transfuse Nonaut Cord Bld Stem Cell in Periph Art, 
Perc
30253Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Periph Art, 
Perc
30253Y1
ICD-10 
Proc
Transfuse Nonaut Hemat Stem Cell in Periph Art, 
Perc
30260G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Central Art, Open
30260G1
ICD-10 
Proc
Transfuse Nonaut Bone Marrow in Central Art, 
Open
30260X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Central Art, 
Open
30260X1
ICD-10 
Proc
Transfuse Nonaut Cord Bld Stem Cell in Central 
Art, Open

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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
30260Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Central Art, 
Open
30260Y1
ICD-10 
Proc
Transfuse Nonaut Hemat Stem Cell in Central Art, 
Open
30263G0
ICD-10 
Proc
Transfuse Autol Bone Marrow in Central Art, Perc
30263G1
ICD-10 
Proc
Transfuse Nonaut Bone Marrow in Central Art, Perc
30263X0
ICD-10 
Proc
Transfuse Autol Cord Bld Stem Cell in Central Art, 
Perc
30263X1
ICD-10 
Proc
Transfuse Nonaut Cord Bld Stem Cell in Central 
Art, Perc
30263Y0
ICD-10 
Proc
Transfuse Autol Hemat Stem Cell in Central Art, 
Perc
30263Y1
ICD-10 
Proc
Transfuse Nonaut Hemat Stem Cell in Central Art, 
Perc
0TY00Z0
ICD-10 
Proc
Transplantation of Right Kidney, Allogeneic, Open 
Approach
0TY00Z1
ICD-10 
Proc
Transplantation of Right Kidney, Syngeneic, Open 
Approach
0TY00Z2
ICD-10 
Proc
Transplantation of Right Kidney, Zooplastic, Open 
Approach
0TY10Z0
ICD-10
Proc
Transplantation of Left Kidney, Allogeneic, Open 
Approach
0TY10Z1
ICD-10 
Proc
Transplantation of Left Kidney, Syngeneic, Open 
Approach
0TY10Z2
ICD-10 
Proc
Transplantation of Left Kidney, Zooplastic, Open 
Approach
02YA0Z0
ICD-10 
Proc
Transplantation of Heart, Allogeneic, Open 
Approach
02YA0Z1
ICD-10 
Proc
Transplantation of Heart, Syngeneic, Open 
Approach
02YA0Z2
ICD-10 
Proc
Transplantation of Heart, Zooplastic, Open 
Approach
07YM0Z0
ICD-10 
Proc
Transplantation of Thymus, Allogeneic, Open 
Approach

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
07YM0Z1
ICD-10 
Proc
Transplantation of Thymus, Syngeneic, Open 
Approach
07YM0Z2
ICD-10 
Proc
Transplantation of Thymus, Zooplastic, Open 
Approach
07YP0Z0
ICD-10 
Proc
Transplantation of Spleen, Allogeneic, Open 
Approach
07YP0Z1
ICD-10 
Proc
Transplantation of Spleen, Syngeneic, Open 
Approach
07YP0Z2
ICD-10 
Proc
Transplantation of Spleen, Zooplastic, Open 
Approach
0BYC0Z0
ICD-10 
Proc
Transplantation of R Up Lung Lobe, Allogen, Open 
Approach
0BYC0Z1
ICD-10 
Proc
Transplantation of R Up Lung Lobe, Syngen, Open 
Approach
0BYC0Z2
ICD-10 
Proc
Transplantation of R Up Lung Lobe, Zooplast, 
Open Approach
0BYD0Z0
ICD-10 
Proc
Transplantation of R Mid Lung Lobe, Allogen, 
Open Approach
0BYD0Z1
ICD-10 
Proc
Transplantation of R Mid Lung Lobe, Syngen, Open 
Approach
0BYD0Z2
ICD-10 
Proc
Transplantation of R Mid Lung Lobe, Zooplast, 
Open Approach
0BYF0Z0
ICD-10 
Proc
Transplantation of R Low Lung Lobe, Allogen, 
Open Approach
0BYF0Z1
ICD-10 
Proc
Transplantation of R Low Lung Lobe, Syngen, 
Open Approach
0BYF0Z2
ICD-10 
Proc
Transplantation of R Low Lung Lobe, Zooplast, 
Open Approach
0BYG0Z0
ICD-10 
Proc
Transplantation of L Up Lung Lobe, Allogen, Open 
Approach
0BYG0Z1
ICD-10 
Proc
Transplantation of L Up Lung Lobe, Syngen, Open 
Approach
0BYG0Z2
ICD-10 
Proc
Transplantation of L Up Lung Lobe, Zooplast, Open 
Approach
0BYH0Z0
ICD-10 
Proc
Transplantation of Lung Lingula, Allogeneic, Open 
Approach

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Stiolto vs Trelegy V1.0 04 May
2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
0BYH0Z1
ICD-10 
Proc
Transplantation of Lung Lingula, Syngeneic, Open 
Approach
0BYH0Z2
ICD-10 
Proc
Transplantation of Lung Lingula, Zooplastic, Open 
Approach
0BYJ0Z0
ICD-10 
Proc
Transplantation of L Low Lung Lobe, Allogen, 
Open Approach
0BYJ0Z1
ICD-10 
Proc
Transplantation of L Low Lung Lobe, Syngen, 
Open Approach
0BYJ0Z2
ICD-10 
Proc
Transplantation of L Low Lung Lobe, Zooplast, 
Open Approach
0BYK0Z0
ICD-10 
Proc
Transplantation of Right Lung, Allogeneic, Open 
Approach
0BYK0Z1
ICD-10 
Proc
Transplantation of Right Lung, Syngeneic, Open 
Approach
0BYK0Z2
ICD-10 
Proc
Transplantation of Right Lung, Zooplastic, Open 
Approach
0BYL0Z0
ICD-10 
Proc
Transplantation of Left Lung, Allogeneic, Open 
Approach
0BYL0Z1
ICD-10 
Proc
Transplantation of Left Lung, Syngeneic, Open 
Approach
0BYL0Z2
ICD-10 
Proc
Transplantation of Left Lung, Zooplastic, Open 
Approach
0BYM0Z0
ICD-10 
Proc
Transplantation of Bilateral Lungs, Allogen, Open 
Approach
0BYM0Z1
ICD-10 
Proc
Transplantation of Bilateral Lungs, Syngeneic, 
Open Approach
0BYM0Z2
ICD-10 
Proc
Transplantation of Bilateral Lungs, Zooplast, Open 
Approach
0DY50Z0
ICD-10 
Proc
Transplantation of Esophagus, Allogeneic, Open 
Approach
0DY50Z1
ICD-10 
Proc
Transplantation of Esophagus, Syngeneic, Open 
Approach
0DY50Z2
ICD-10 
Proc
Transplantation of Esophagus, Zooplastic, Open 
Approach
0DY60Z0
ICD-10 
Proc
Transplantation of Stomach, Allogeneic, Open 
Approach

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
0DY60Z1
ICD-10 
Proc
Transplantation of Stomach, Syngeneic, Open 
Approach
0DY60Z2
ICD-10 
Proc
Transplantation of Stomach, Zooplastic, Open 
Approach
0DY80Z0
ICD-10 
Proc
Transplantation of Small Intestine, Allogen, Open 
Approach
0DY80Z1
ICD-10 
Proc
Transplantation of Small Intestine, Syngeneic, Open 
Approach
0DY80Z2
ICD-10 
Proc
Transplantation of Small Intestine, Zooplast, Open 
Approach
0DYE0Z0
ICD-10 
Proc
Transplantation of Large Intestine, Allogen, Open 
Approach
0DYE0Z1
ICD-10 
Proc
Transplantation of Large Intestine, Syngeneic, Open 
Approach
0DYE0Z2
ICD-10 
Proc
Transplantation of Large Intestine, Zooplast, Open 
Approach
0FY00Z0
ICD-10 
Proc
Transplantation of Liver, Allogeneic, Open 
Approach
0FY00Z1
ICD-10 
Proc
Transplantation of Liver, Syngeneic, Open 
Approach
0FY00Z2
ICD-10 
Proc
Transplantation of Liver, Zooplastic, Open 
Approach
0FYG0Z0
ICD-10 
Proc
Transplantation of Pancreas, Allogeneic, Open 
Approach
0FYG0Z1
ICD-10 
Proc
Transplantation of Pancreas, Syngeneic, Open 
Approach
0FYG0Z2
ICD-10 
Proc
Transplantation of Pancreas, Zooplastic, Open 
Approach
0UY00Z0
ICD-10 
Proc
Transplantation of Right Ovary, Allogeneic, Open 
Approach
0UY00Z1
ICD-10 
Proc
Transplantation of Right Ovary, Syngeneic, Open 
Approach
0UY00Z2
ICD-10 
Proc
Transplantation of Right Ovary, Zooplastic, Open 
Approach
0UY10Z0
ICD-10 
Proc
Transplantation of Left Ovary, Allogeneic, Open 
Approach

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
0UY10Z1
ICD-10 
Proc
Transplantation of Left Ovary, Syngeneic, Open 
Approach
0UY10Z2
ICD-10 
Proc
Transplantation of Left Ovary, Zooplastic, Open 
Approach
0UY90Z0
ICD-10 
Proc
Transplantation of Uterus, Allogeneic, Open 
Approach
0UY90Z1
ICD-10 
Proc
Transplantation of Uterus, Syngeneic, Open 
Approach
0UY90Z2
ICD-10 
Proc
Transplantation of Uterus, Zooplastic, Open 
Approach
0WY20Z0
ICD-10 
Proc
Transplantation of Face, Allogeneic, Open 
Approach
0WY20Z1
ICD-10 
Proc
Transplantation of Face, Syngeneic, Open Approach
0XYJ0Z0
ICD-10 
Proc
Transplantation of Right Hand, Allogeneic, Open 
Approach
0XYJ0Z1
ICD-10 
Proc
Transplantation of Right Hand, Syngeneic, Open 
Approach
0XYK0Z0
ICD-10 
Proc
Transplantation of Left Hand, Allogeneic, Open 
Approach
0XYK0Z1
ICD-10 
Proc
Transplantation of Left Hand, Syngeneic, Open 
Approach
3E030U0
ICD-10 
Proc
Introduce Autol Pancr Islet in Periph Vein, Open
3E030U1
ICD-10 
Proc
Introduce Nonaut Pancr Islet in Periph Vein, Open
3E033U0
ICD-10 
Proc
Introduce Autol Pancr Islet in Periph Vein, Perc
3E033U1
ICD-10 
Proc
Introduce Nonaut Pancr Islet in Periph Vein, Perc
3E0J3U0
ICD-10 
Proc
Introduce Autol Pancr Islet in Bil/Panc Tract, Perc
3E0J3U1
ICD-10 
Proc
Introduce Nonaut Pancr Islet in Bil/Panc Tract, Perc
3E0J7U0
ICD-10 
Proc
Introduce Autol Pancr Islet in Bil/Panc Tract, Via 
Opening

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Stiolto vs Trelegy V1.0 04 May
2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
3E0J7U1
ICD-10 
Proc
Introduce Nonaut Pancr Islet in Bil/Panc Tract, Via 
Opening
3E0J8U0
ICD-10 
Proc
Introduction of Autol Pancr Islet into Bil/Panc 
Tract, Endo
3E0J8U1
ICD-10 
Proc
Introduction of Nonaut Pancr Islet into Bil/Panc 
Tract, Endo
V580 
ICD-9 
Dx
RADIOTHERAPY ENCOUNTER
V581 
ICD-9 
Dx
CHEMOTHERAPY ENCOUNTER (End 2005)
V5811
ICD-9 
Dx
ANTINEOPLASTIC CHEMO ENC (Begin 2005)
V5812
ICD-9 
Dx
IMMUNOTHERAPY ENCOUNTER (Begin 2005)
V661 
ICD-9 
Dx
RADIOTHERAPY CONVALESCEN
V662 
ICD-9 
Dx
CHEMOTHERAPY CONVALESCEN
V671 
ICD-9 
Dx
RADIOTHERAPY FOLLOW-UP
V672 
ICD-9 
Dx
CHEMOTHERAPY FOLLOW-UP
V520 
ICD-9 
Dx
FITTING ARTIFICIAL ARM
V521 
ICD-9 
Dx
FITTING ARTIFICIAL LEG
V524 
ICD-9 
Dx
FITTING BREAST PROSTHES
V528 
ICD-9 
Dx
FITTING PROSTHESIS NEC
V529 
ICD-9 
Dx
FITTING PROSTHESIS NOS
V538 
ICD-9 
Dx
ADJUSTMENT OF WHEELCHAIR
V570 
ICD-9 
Dx
BREATHING EXERCISES

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2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
V571 
ICD-9 
Dx
PHYSICAL THERAPY NEC
V572 
ICD-9 
Dx
OCCUPAT/VOCATION THERAPY (End 1994)
V5721
ICD-9 
Dx
OCCUP THER ENCOUNTER (Begin 1994)
V5722
ICD-9 
Dx
VOCATIONAL THER ENCOUNTER (Begin 
1994)
V573 
ICD-9 
Dx
SPEECH THERAPY
V574 
ICD-9 
Dx
ORTHOPTIC TRAINING
V5781
ICD-9 
Dx
ORTHOTIC TRAINING
V5789
ICD-9 
Dx
REHABILITATION PROC NEC
V579 
ICD-9 
Dx
REHABILITATION PROC NOS
V5882
ICD-9 
Dx
FIT ADJUST NONVASC CATH (Begin 1995)
410
ICD-9 
Proc
BONE MARROW TRNSPLNT (Begin 1980 End 
1988)
4100
ICD-9 
Proc
BONE MARROW TRNSPLNT NOS (Begin 1988)
4101
ICD-9 
Proc
AUT BONE MARROW TRNSPLNT (Begin 1988)
4102
ICD-9 
Proc
ALO BONE MARROW TRNSPLNT (Begin 1988)
4103
ICD-9 
Proc
ALLOGRFT BONE MARROW NOS (Begin 1988)
4104
ICD-9 
Proc
AUTOL HEMATOPO STEM CELL TRANSPLNT 
(Begin 1994)
4105
ICD-9 
Proc
ALLOGEN HEMATO STEM CELL TRANS 
(Begin 1997)
4106
ICD-9 
Proc
CORD BLOOD STEM CELL TRANS (Begin 
1997)

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2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
4107
ICD-9 
Proc
AUTOL HEMAT STEM CELL TRANS 
W/PURGING (Begin 2000)
4108
ICD-9 
Proc
ALLOGEN HEMAT STEM CELL TRANS 
W/PURGING (Begin 2000)
4109
ICD-9 
Proc
AUTOL BONE MARROW TRANS W/PURGING 
(Begin 2000)
5561
ICD-9 
Proc
RENAL AUTOTRANSPLANT
5569
ICD-9 
Proc
KIDNEY TRANSPLANT NEC
335
ICD-9 
Proc
LUNG TRANSPLANT (End 1995)
3350
ICD-9 
Proc
LUNG TRANSPL NOS (Begin 1995)
3351
ICD-9 
Proc
UNILAT LUNG TRANSPL (Begin 1995)
3352
ICD-9 
Proc
BILAT LUNG TRANSPL (Begin 1995)
336
ICD-9 
Proc
COMB HEART/LUNG TRANSPLA (Begin 1990)
375
ICD-9 
Proc
HEART TRANSPLANTATION (End 2003)
3751
ICD-9 
Proc
HEART TRANSPLANTATION (Begin 2003)
4194
ICD-9 
Proc
SPLEEN TRANSPLANTATION
4697
ICD-9 
Proc
TRANSPLANT OF INTESTINE (Begin 2000)
5051
ICD-9 
Proc
AUXILIARY LIVER TRANSPL
5059
ICD-9 
Proc
LIVER TRANSPLANT NEC
5280
ICD-9 
Proc
PANCREAT TRANSPLANT NOS
5281
ICD-9 
Proc
REIMPLANT PANCREATIC TIS

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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
5282
ICD-9 
Proc
PANCREATIC HOMOTRANSPLAN
5283
ICD-9 
Proc
PANCREATIC HETEROTRANSPL
5284
ICD-9 
Proc
AUTOTRANS ISLET CELLS (Begin 1996)
5285
ICD-9 
Proc
ALLOTRANS ISLET CELLS (Begin 1996)
5286
ICD-9 
Proc
TRANSPL ISLET CELLS NOS (Begin 1996)
Allergic 
rhinitis
477
ICD-9 
Dx
Allergic rhinitis 
477.0
ICD-9 
Dx
Allergic rhinitis due to pollen
477.1
ICD-9 
Dx
Allergic rhinitis, due to food
477.2
ICD-9 
Dx
Allergic rhinitis due to animal (cat) (dog) hair and 
dander
477.8
ICD-9 
Dx
Allergic rhinitis due to other allergen
477.9
ICD-9 
Dx
Allergic rhinitis, cause unspecified
J30
ICD-10 
Dx
Vasomotor and allergic rhinitis
J300
ICD-10 
Dx
Vasomotor rhinitis
J301
ICD-10 
Dx
Allergic rhinitis due to pollen
J302
ICD-10 
Dx
Other seasonal allergic rhinitis
J305
ICD-10 
Dx
Allergic rhinitis due to food
J3081
ICD-10 
Dx
Allergic rhinitis due to animal (cat) (dog) hair and 
dander
J3089
ICD-10 
Dx
Other allergic rhinitis

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
J309
ICD-10 
Dx
Allergic rhinitis, unspecified
Anxiety 
(narrow)
293.84
ICD-9 
Dx
Anxiety disorder in conditions classified elsewhere
300.00
ICD-9 
Dx
Anxiety state, unspecified
300.02
ICD-9 
Dx
Generalized anxiety disorder
300.09
ICD-9 
Dx
Other anxiety states
F064
ICD-10 
Dx
Anxiety disorder due to known physiological 
condition
F411
ICD-10 
Dx
Generalized anxiety disorder
F413
ICD-10 
Dx
Other mixed anxiety disorders
F418
ICD-10 
Dx
Other specified anxiety disorders
F419
ICD-10 
Dx
Anxiety disorder, unspecified
F940
ICD-10 
Dx
Selective mutism
Anxiety 
(broad)
293.84
ICD-9 
Dx
Anxiety disorder in conditions classified elsewhere
300.00
ICD-9 
Dx
Anxiety state, unspecified
300.02
ICD-9 
Dx
Generalized anxiety disorder
300.09
ICD-9 
Dx
Other anxiety states
300.01
ICD-9 
Dx
Panic Disorder without Agoraphobia
300.20
ICD-9 
Dx
Phobia, unspecified
300.21
ICD-9 
Dx
Agoraphobia with panic disorder

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001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
300.22
ICD-9 
Dx
Agoraphobia without mention of panic attacks
300.23
ICD-9 
Dx
Social phobia
300.29
ICD-9 
Dx
Other isolated or specific phobias
309.21
ICD-9 
Dx
Separation anxiety disorder
313.23
ICD-9 
Dx
Selective mutism
F10180
ICD-10 
Dx
Alcohol abuse with alcohol-induced anxiety 
disorder
F10280
ICD-10 
Dx
Alcohol dependence with alcohol-induced anxiety 
disorder
F10980
ICD-10 
Dx
Alcohol use, unspecified with alcohol-induced 
anxiety disorder
F12180
ICD-10 
Dx
Cannabis abuse with cannabis-induced anxiety 
disorder
F12280
ICD-10 
Dx
Cannabis dependence with cannabis-induced 
anxiety disorder
F12980
ICD-10 
Dx
Cannabis use, unspecified with anxiety disorder
F13180
ICD-10 
Dx
Sedative, hypnotic or anxiolytic abuse with 
sedative, hypnotic or anxiolytic-induced anxiety 
disorder
F13280
ICD-10 
Dx
Sedative, hypnotic or anxiolytic dependence with 
sedative, hypnotic or anxiolytic-induced anxiety 
disorder
F13980
ICD-10 
Dx
Sedative, hypnotic or anxiolytic use, unspecified 
with sedative, hypnotic or anxiolytic-induced 
anxiety disorder
F14180
ICD-10 
Dx
Cocaine abuse with cocaine-induced anxiety 
disorder
F14280
ICD-10 
Dx
Cocaine dependence with cocaine-induced anxiety 
disorder
F14980
ICD-10 
Dx
Cocaine use, unspecified with cocaine-induced 
anxiety disorder

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F15180
ICD-10 
Dx
Other stimulant abuse with stimulant-induced 
anxiety disorder
F15280
ICD-10 
Dx
Other stimulant dependence with stimulant-induced 
anxiety disorder
F15980
ICD-10 
Dx
Other stimulant use, unspecified with stimulant-
induced anxiety disorder
F16180
ICD-10 
Dx
Hallucinogen abuse with hallucinogen-induced 
anxiety disorder
F16280
ICD-10 
Dx
Hallucinogen dependence with hallucinogen-
induced anxiety disorder
F16980
ICD-10 
Dx
Hallucinogen use, unspecified with hallucinogen-
induced anxiety disorder
F18180
ICD-10 
Dx
Inhalant abuse with inhalant-induced anxiety 
disorder
F18280
ICD-10 
Dx
Inhalant dependence with inhalant-induced anxiety 
disorder
F18980
ICD-10
Dx
Inhalant use, unspecified with inhalant-induced 
anxiety disorder
F19180
ICD-10 
Dx
Other psychoactive substance abuse with 
psychoactive substance-induced anxiety disorder
F19280
ICD-10 
Dx
Other psychoactive substance dependence with 
psychoactive substance-induced anxiety disorder
F19980
ICD-10 
Dx
Other psychoactive substance use, unspecified with 
psychoactive substance-induced anxiety disorder
F4000
ICD-10 
Dx
Agoraphobia, unspecified
F4001
ICD-10 
Dx
Agoraphobia with panic disorder
F4002
ICD-10 
Dx
Agoraphobia without panic disorder
F4010
ICD-10 
Dx
Social phobia, unspecified
F4011
ICD-10 
Dx
Social phobia, generalized
F40210
ICD-10 
Dx
Arachnophobia

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F40218
ICD-10 
Dx
Other animal type phobia
F40220
ICD-10 
Dx
Fear of thunderstorms
F40228
ICD-10 
Dx
Other natural environment type phobia
F40230
ICD-10 
Dx
Fear of blood
F40231
ICD-10 
Dx
Fear of injections and transfusions
F40232
ICD-10 
Dx
Fear of other medical care
F40233
ICD-10 
Dx
Fear of injury
F40240
ICD-10 
Dx
Claustrophobia
F40241
ICD-10 
Dx
Acrophobia
F40242
ICD-10 
Dx
Fear of bridges
F40243
ICD-10 
Dx
Fear of flying
F40248
ICD-10 
Dx
Other situational type phobia
F40290
ICD-10 
Dx
Androphobia
F40291
ICD-10 
Dx
Gynephobia
F40298
ICD-10 
Dx
Other specified phobia
F408
ICD-10 
Dx
Other phobic anxiety disorders
F409
ICD-10 
Dx
Phobic anxiety disorder, unspecified
F410
ICD-10 
Dx
Panic disorder [episodic paroxysmal anxiety] 
without agoraphobia

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F930
ICD-10 
Dx
Separation anxiety disorder of childhood
F064
ICD-10 
Dx
Anxiety disorder due to known physiological 
condition
F411
ICD-10 
Dx
Generalized anxiety disorder
F413
ICD-10 
Dx
Other mixed anxiety disorders
F418
ICD-10 
Dx
Other specified anxiety disorders
F419
ICD-10 
Dx
Anxiety disorder, unspecified
F940
ICD-10 
Dx
Selective mutism
Arrythmia
427.2
ICD-9 
Dx
Unspecified paroxysmal tachycardia
427.31
ICD-9 
Dx
Atrial fibrillation
427.9
ICD-9 
Dx
Unspecified cardiac dysrhythmia
427.0
ICD-9 
Dx
Paroxysmal supraventricular tachycardia
427.60
ICD-9 
Dx
Unspecified premature beats
427.1
ICD-9 
Dx
Paroxysmal ventricular tachycardia
427.32
ICD-9 
Dx
Atrial flutter
427.41
ICD-9 
Dx
Ventricular fibrillation
427.42
ICD-9 
Dx
Ventricular flutter
427.5
ICD-9 
Dx
Cardiac arrest
427.81
ICD-9 
Dx
Sinoatrial node dysfunction

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427.89
ICD-9 
Dx
Other specified cardiac dysrhythmias
I471
ICD-10 
Dx
Supraventricular tachycardia
I479
ICD-10 
Dx
Paroxysmal tachycardia, unspecified
I480
ICD-10 
Dx
Paroxysmal atrial fibrillation
I482
ICD-10 
Dx
Chronic atrial fibrillation
I4891
ICD-10 
Dx
Unspecified atrial fibrillation
I492
ICD-10 
Dx
Junctional premature depolarization
I4940
ICD-10 
Dx
Unspecified premature depolarization
I499
ICD-10 
Dx
Cardiac arrhythmia, unspecified
I462
ICD-10 
Dx
Cardiac arrest due to underlying cardiac condition
I468
ICD-10 
Dx
Cardiac arrest due to other underlying condition
I469
ICD-10 
Dx
Cardiac arrest, cause unspecified
I470
ICD-10 
Dx
Re-entry ventricular arrhythmia
I471
ICD-10 
Dx
Supraventricular tachycardia
I472
ICD-10 
Dx
Ventricular tachycardia
I479
ICD-10 
Dx
Paroxysmal tachycardia, unspecified
I480
ICD-10 
Dx
Paroxysmal atrial fibrillation
I481
ICD-10 
Dx
Persistent atrial fibrillation

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I482
ICD-10 
Dx
Chronic atrial fibrillation
I483
ICD-10 
Dx
Typical atrial flutter
I484
ICD-10 
Dx
Atypical atrial flutter
I4891
ICD-10 
Dx
Unspecified atrial fibrillation
I4892
ICD-10 
Dx
Unspecified atrial flutter
I4901
ICD-10 
Dx
Ventricular fibrillation
I4902
ICD-10 
Dx
Ventricular flutter
I491
ICD-10 
Dx
Atrial premature depolarization
I492
ICD-10 
Dx
Junctional premature depolarization
I493
ICD-10 
Dx
Ventricular premature depolarization
I4940
ICD-10 
Dx
Unspecified premature depolarization
I4949
ICD-10 
Dx
Other premature depolarization
I495
ICD-10 
Dx
Sick sinus syndrome
I498
ICD-10 
Dx
Other specified cardiac arrhythmias
I499
ICD-10 
Dx
Cardiac arrhythmia, unspecified
Atrial 
fibrillation 
(narrow)
427.31
ICD-9 
Dx
Atrial fibrillation
I480
ICD-10 
Dx
Paroxysmal atrial fibrillation
I481
ICD-10 
Dx
Persistent atrial fibrillation

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I482
ICD-10 
Dx
Chronic atrial fibrillation
I4891
ICD-10 
Dx
Unspecified atrial fibrillation 
Atrial 
fibrillation 
(broad)
427.31
ICD-9 
Dx
Atrial fibrillation
427.32
ICD-9 
Dx
Atrial flutter
I480
ICD-10 
Dx
Paroxysmal atrial fibrillation
I481
ICD-10 
Dx
Persistent atrial fibrillation
I482
ICD-10 
Dx
Chronic atrial fibrillation
I483
ICD-10 
Dx
Typical atrial flutter 
I484
ICD-10 
Dx
Atypical atrial flutter 
I4891
ICD-10 
Dx
Unspecified atrial fibrillation 
I4892
ICD-10 
Dx
Unspecified atrial flutter 
Acute 
sinusitis 
461
ICD-9 
Dx
Acute sinusitis
461.0
ICD-9 
Dx
Acute maxillary sinusitis
461.1
ICD-9 
Dx
Acute frontal sinusitis
461.2
ICD-9 
Dx
Acute ethmoidal sinusitis
461.3
ICD-9 
Dx
Acute sphenoidal sinusitis
461.8
ICD-9 
Dx
Other acute sinusitis
461.9
ICD-9 
Dx
Acute sinusitis, unspecified

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J01
ICD-10 
Dx
Acute sinusitis
J010  
ICD-10 
Dx
Acute maxillary sinusitis  
J0100
ICD-10 
Dx
Acute maxillary sinusitis, unspecified  
J0101
ICD-10 
Dx
Acute recurrent maxillary sinusitis  
J011  
ICD-10 
Dx
Acute frontal sinusitis  
J0110  
ICD-10 
Dx
Acute frontal sinusitis, unspecified    
J0111  
ICD-10 
Dx
Acute recurrent frontal sinusitis  
J012
ICD-10 
Dx
Acute ethmoidal sinusitis
J0120
ICD-10 
Dx
Acute ethmoidal sinusitis, unspecified  
J0121
ICD-10 
Dx
Acute recurrent ethmoidal sinusitis
J013
ICD-10 
Dx
Acute sphenoidal sinusitis 
J0130
ICD-10 
Dx
Acute sphenoidal sinusitis, unspecified   
J0131
ICD-10 
Dx
Acute recurrent sphenoidal sinusitis 
J014
ICD-10 
Dx
Acute pansinusitis 
J0140
ICD-10 
Dx
Acute pansinusitis, unspecified   
J0141
ICD-10 
Dx
Acute recurrent pansinusitis 
J018
ICD-10 
Dx
Other acute sinusitis 
J0180
ICD-10 
Dx
Other acute sinusitis, unspecified   

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J0181
ICD-10 
Dx
Other acute recurrent sinusitis 
J019
ICD-10 
Dx
Acute sinusitis, unspecified 
J0190
ICD-10 
Dx
Acute sinusitis, unspecified 
J0191
ICD-10 
Dx
Acute recurrent sinusitis, unspecified 
Candidiasi
s
B370
ICD-10 
Dx
Candidal stomatitis
B371
ICD-10 
Dx
Pulmonary candidiasis
B372
ICD-10 
Dx
Candidiasis of skin and nail
B373
ICD-10 
Dx
Candidiasis of vulva and vagina
B3741
ICD-10 
Dx
Candidal cystitis and urethritis
B3742
ICD-10 
Dx
Candidal balanitis
B3749
ICD-10 
Dx
Other urogenital candidiasis
B375
ICD-10 
Dx
Candidal meningitis
B376
ICD-10 
Dx
Candidal endocarditis
B377
ICD-10 
Dx
Candidal sepsis
B3781
ICD-10 
Dx
Candidal esophagitis
B3782
ICD-10 
Dx
Candidal enteritis
B3783
ICD-10 
Dx
Candidal cheilitis
B3784
ICD-10 
Dx
Candidal otitis externa

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B3789
ICD-10 
Dx
Other sites of candidiasis
B379
ICD-10 
Dx
Candidiasis, unspecified
112.0
ICD-9 
Dx
Candidiasis of mouth
112.1
ICD-9 
Dx
Candidiasis of vulva and vagina
112.2
ICD-9 
Dx
Candidiasis of other urogenital sites
112.3
ICD-9 
Dx
Candidiasis of skin and nails
112.4
ICD-9 
Dx
Candidiasis of lung
112.5
ICD-9 
Dx
Disseminated candidiasis
112.81
ICD-9 
Dx
Candidal endocarditis
112.82
ICD-9 
Dx
Candidal otitis externa
112.83
ICD-9 
Dx
Candidal meningitis
112.84
ICD-9 
Dx
Candidiasis of the esophagus
112.85
ICD-9 
Dx
Candidiasis of the intestine
112.89
ICD-9 
Dx
Other candidiasis of other specified sites
112.9
ICD-9 
Dx
Candidiasis of unspecified site
Cataracts
E0836
ICD-10
Dx
Diabetes mellitus due to underlying condition with 
diabetic cataract
E0936
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic cataract
E1036
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic cataract

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E1136
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic cataract
E1336
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
cataract
H25011
ICD-10 
Dx
Cortical age-related cataract, right eye
H25012
ICD-10 
Dx
Cortical age-related cataract, left eye
H25013
ICD-10 
Dx
Cortical age-related cataract, bilateral
H25019
ICD-10 
Dx
Cortical age-related cataract, unspecified eye
H25031
ICD-10 
Dx
Anterior subcapsular polar age-related cataract, 
right eye
H25032
ICD-10 
Dx
Anterior subcapsular polar age-related cataract, left 
eye
H25033
ICD-10 
Dx
Anterior subcapsular polar age-related cataract, 
bilateral
H25039
ICD-10 
Dx
Anterior subcapsular polar age-related cataract, 
unspecified eye
H25041
ICD-10 
Dx
Posterior subcapsular polar age-related cataract, 
right eye
H25042
ICD-10 
Dx
Posterior subcapsular polar age-related cataract, left 
eye
H25043
ICD-10 
Dx
Posterior subcapsular polar age-related cataract, 
bilateral
H25049
ICD-10 
Dx
Posterior subcapsular polar age-related cataract, 
unspecified eye
H25091
ICD-10 
Dx
Other age-related incipient cataract, right eye
H25092
ICD-10 
Dx
Other age-related incipient cataract, left eye
H25093
ICD-10 
Dx
Other age-related incipient cataract, bilateral
H25099
ICD-10 
Dx
Other age-related incipient cataract, unspecified eye

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H2510
ICD-10 
Dx
Age-related nuclear cataract, unspecified eye
H2511
ICD-10 
Dx
Age-related nuclear cataract, right eye
H2512
ICD-10 
Dx
Age-related nuclear cataract, left eye
H2513
ICD-10 
Dx
Age-related nuclear cataract, bilateral
H2520
ICD-10 
Dx
Age-related cataract, morgagnian type, unspecified 
eye
H2521
ICD-10 
Dx
Age-related cataract, morgagnian type, right eye
H2522
ICD-10 
Dx
Age-related cataract, morgagnian type, left eye
H2523
ICD-10 
Dx
Age-related cataract, morgagnian type, bilateral
H25811
ICD-10 
Dx
Combined forms of age-related cataract, right eye
H25812
ICD-10 
Dx
Combined forms of age-related cataract, left eye
H25813
ICD-10 
Dx
Combined forms of age-related cataract, bilateral
H25819
ICD-10 
Dx
Combined forms of age-related cataract, unspecified 
eye
H2589
ICD-10 
Dx
Other age-related cataract
H259
ICD-10 
Dx
Unspecified age-related cataract
H26001
ICD-10 
Dx
Unspecified infantile and juvenile cataract, right eye
H26002
ICD-10 
Dx
Unspecified infantile and juvenile cataract, left eye
H26003
ICD-10 
Dx
Unspecified infantile and juvenile cataract, bilateral
H26009
ICD-10 
Dx
Unspecified infantile and juvenile cataract, 
unspecified eye

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H26011
ICD-10 
Dx
Infantile and juvenile cortical, lamellar, or zonular 
cataract, right eye
H26012
ICD-10 
Dx
Infantile and juvenile cortical, lamellar, or zonular 
cataract, left eye
H26013
ICD-10 
Dx
Infantile and juvenile cortical, lamellar, or zonular 
cataract, bilateral
H26019
ICD-10 
Dx
Infantile and juvenile cortical, lamellar, or zonular 
cataract, unspecified eye
H26031
ICD-10 
Dx
Infantile and juvenile nuclear cataract, right eye
H26032
ICD-10 
Dx
Infantile and juvenile nuclear cataract, left eye
H26033
ICD-10 
Dx
Infantile and juvenile nuclear cataract, bilateral
H26039
ICD-10 
Dx
Infantile and juvenile nuclear cataract, unspecified 
eye
H26041
ICD-10 
Dx
Anterior subcapsular polar infantile and juvenile 
cataract, right eye
H26042
ICD-10 
Dx
Anterior subcapsular polar infantile and juvenile 
cataract, left eye
H26043
ICD-10 
Dx
Anterior subcapsular polar infantile and juvenile 
cataract, bilateral
H26049
ICD-10 
Dx
Anterior subcapsular polar infantile and juvenile 
cataract, unspecified eye
H26051
ICD-10 
Dx
Posterior subcapsular polar infantile and juvenile 
cataract, right eye
H26052
ICD-10 
Dx
Posterior subcapsular polar infantile and juvenile 
cataract, left eye
H26053
ICD-10 
Dx
Posterior subcapsular polar infantile and juvenile 
cataract, bilateral
H26059
ICD-10 
Dx
Posterior subcapsular polar infantile and juvenile 
cataract, unspecified eye
H26061
ICD-10 
Dx
Combined forms of infantile and juvenile cataract, 
right eye
H26062
ICD-10 
Dx
Combined forms of infantile and juvenile cataract, 
left eye

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H26063
ICD-10 
Dx
Combined forms of infantile and juvenile cataract, 
bilateral
H26069
ICD-10 
Dx
Combined forms of infantile and juvenile cataract, 
unspecified eye
H2609
ICD-10 
Dx
Other infantile and juvenile cataract
H26101
ICD-10 
Dx
Unspecified traumatic cataract, right eye
H26102
ICD-10 
Dx
Unspecified traumatic cataract, left eye
H26103
ICD-10 
Dx
Unspecified traumatic cataract, bilateral
H26109
ICD-10 
Dx
Unspecified traumatic cataract, unspecified eye
H26121
ICD-10 
Dx
Partially resolved traumatic cataract, right eye
H26122
ICD-10 
Dx
Partially resolved traumatic cataract, left eye
H26123
ICD-10 
Dx
Partially resolved traumatic cataract, bilateral
H26129
ICD-10 
Dx
Partially resolved traumatic cataract, unspecified 
eye
H26131
ICD-10 
Dx
Total traumatic cataract, right eye
H26132
ICD-10 
Dx
Total traumatic cataract, left eye
H26133
ICD-10 
Dx
Total traumatic cataract, bilateral
H26139
ICD-10 
Dx
Total traumatic cataract, unspecified eye
H2620
ICD-10 
Dx
Unspecified complicated cataract
H26211
ICD-10 
Dx
Cataract with neovascularization, right eye
H26212
ICD-10 
Dx
Cataract with neovascularization, left eye

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H26213
ICD-10 
Dx
Cataract with neovascularization, bilateral
H26219
ICD-10 
Dx
Cataract with neovascularization, unspecified eye
H26221
ICD-10 
Dx
Cataract secondary to ocular disorders 
(degenerative) (inflammatory), right eye
H26222
ICD-10 
Dx
Cataract secondary to ocular disorders 
(degenerative) (inflammatory), left eye
H26223
ICD-10 
Dx
Cataract secondary to ocular disorders 
(degenerative) (inflammatory), bilateral
H26229
ICD-10 
Dx
Cataract secondary to ocular disorders 
(degenerative) (inflammatory), unspecified eye
H2630
ICD-10 
Dx
Drug-induced cataract, unspecified eye
H2631
ICD-10 
Dx
Drug-induced cataract, right eye
H2632
ICD-10 
Dx
Drug-induced cataract, left eye
H2633
ICD-10 
Dx
Drug-induced cataract, bilateral
H2640
ICD-10 
Dx
Unspecified secondary cataract
H26491
ICD-10 
Dx
Other secondary cataract, right eye
H26492
ICD-10 
Dx
Other secondary cataract, left eye
H26493
ICD-10 
Dx
Other secondary cataract, bilateral
H26499
ICD-10 
Dx
Other secondary cataract, unspecified eye
H268
ICD-10 
Dx
Other specified cataract
H269
ICD-10 
Dx
Unspecified cataract
H28
ICD-10 
Dx
Cataract in diseases classified elsewhere

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H59011
ICD-10 
Dx
Keratopathy (bullous aphakic) following cataract 
surgery, right eye
H59012
ICD-10 
Dx
Keratopathy (bullous aphakic) following cataract 
surgery, left eye
H59013
ICD-10 
Dx
Keratopathy (bullous aphakic) following cataract 
surgery, bilateral
H59019
ICD-10 
Dx
Keratopathy (bullous aphakic) following cataract 
surgery, unspecified eye
H59021
ICD-10 
Dx
Cataract (lens) fragments in eye following cataract 
surgery, right eye
H59022
ICD-10 
Dx
Cataract (lens) fragments in eye following cataract 
surgery, left eye
H59023
ICD-10
Dx
Cataract (lens) fragments in eye following cataract 
surgery, bilateral
H59029
ICD-10 
Dx
Cataract (lens) fragments in eye following cataract 
surgery, unspecified eye
H59031
ICD-10 
Dx
Cystoid macular edema following cataract surgery, 
right eye
H59032
ICD-10 
Dx
Cystoid macular edema following cataract surgery, 
left eye
H59033
ICD-10 
Dx
Cystoid macular edema following cataract surgery, 
bilateral
H59039
ICD-10 
Dx
Cystoid macular edema following cataract surgery, 
unspecified eye
H59091
ICD-10 
Dx
Other disorders of the right eye following cataract 
surgery
H59092
ICD-10 
Dx
Other disorders of the left eye following cataract 
surgery
H59093
ICD-10 
Dx
Other disorders of the eye following cataract 
surgery, bilateral
H59099
ICD-10 
Dx
Other disorders of unspecified eye following 
cataract surgery
Q120
ICD-10 
Dx
Congenital cataract
Z9841
ICD-10 
Dx
Cataract extraction status, right eye

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Z9842
ICD-10 
Dx
Cataract extraction status, left eye
Z9849
ICD-10 
Dx
Cataract extraction status, unspecified eye
366.00
ICD-9 
Dx
Unspecified nonsenile cataract
366.01
ICD-9 
Dx
Anterior subcapsular polar cataract, nonsenile
366.02
ICD-9 
Dx
Posterior subcapsular polar cataract, nonsenile
366.03
ICD-9 
Dx
Cortical, lamellar, or zonular cataract, nonsenile
366.04
ICD-9 
Dx
Nuclear cataract, nonsenile
366.09
ICD-9 
Dx
Other and combined forms of nonsenile cataract
366.10
ICD-9 
Dx
Unspecified senile cataract
366.12
ICD-9 
Dx
Incipient cataract
366.13
ICD-9 
Dx
Anterior subcapsular polar senile cataract
366.14
ICD-9 
Dx
Posterior subcapsular polar senile cataract
366.15
ICD-9 
Dx
Cortical senile cataract
366.17
ICD-9 
Dx
Total or mature senile cataract
366.18
ICD-9 
Dx
Hypermature senile cataract
366.19
ICD-9 
Dx
Other and combined forms of senile cataract
366.20
ICD-9 
Dx
Unspecified traumatic cataract
366.21
ICD-9 
Dx
Localized traumatic opacities of cataract

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366.22
ICD-9 
Dx
Total traumatic cataract
366.23
ICD-9 
Dx
Partially resolved traumatic cataract
366.30
ICD-9 
Dx
Unspecified cataracta complicata
366.31
ICD-9 
Dx
Cataract secondary to glaucomatous flecks 
(subcapsular)
366.32
ICD-9 
Dx
Cataract in inflammatory ocular disorders
366.33
ICD-9 
Dx
Cataract with ocular neovascularization
366.34
ICD-9 
Dx
Cataract in degenerative ocular disorders
366.41
ICD-9 
Dx
Diabetic cataract
366.42
ICD-9 
Dx
Tetanic cataract
366.43
ICD-9 
Dx
Myotonic cataract
366.44
ICD-9 
Dx
Cataract associated with other syndromes
366.45
ICD-9 
Dx
Toxic cataract
366.46
ICD-9 
Dx
Cataract associated with radiation and other 
physical influences
366.50
ICD-9 
Dx
Unspecified after-cataract
366.52
ICD-9 
Dx
Other after-cataract, not obscuring vision
366.53
ICD-9 
Dx
After-cataract, obscuring vision
366.8
ICD-9 
Dx
Other cataract
366.9
ICD-9 
Dx
Unspecified cataract

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743.30
ICD-9 
Dx
Unspecified congenital cataract
743.31
ICD-9 
Dx
Congenital capsular and subcapsular cataract
743.32
ICD-9 
Dx
Congenital cortical and zonular cataract
743.33
ICD-9 
Dx
Congenital nuclear cataract
743.34
ICD-9 
Dx
Congenital total and subtotal cataract
743.39
ICD-9 
Dx
Other congenital cataract and lens anomalies
998.82
ICD-9 
Dx
Cataract fragments in eye following surgery
V45.61
ICD-9 
Dx
Cataract extraction status
Chronic 
sinusitis
473
ICD-9 
Dx
Chronic sinusitis
473.0
ICD-9 
Dx
Maxillary chronic sinusitis
473.1
ICD-9 
Dx
Frontal chronic sinusitis
473.2
ICD-9 
Dx
Ethmoidal chronic sinusitis
473.3
ICD-9 
Dx
Sphenoidal chronic sinusitis
473.8
ICD-9 
Dx
Other chronic sinusitis
473.9
ICD-9 
Dx
Unspecified sinusitis (chronic) 
J32
ICD-10 
Dx
Chronic sinusitis
J320  
ICD-10 
Dx
Chronic maxillary sinusitis  
J321  
ICD-10 
Dx
Chronic frontal sinusitis  

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J322
ICD-10 
Dx
Chronic ethmoidal sinusitis
J323
ICD-10 
Dx
Chronic sphenoidal sinusitis 
J324
ICD-10 
Dx
Chronic pansinusitis 
J328
ICD-10 
Dx
Other chronic sinusitis 
J329
ICD-10 
Dx
Chronic sinusitis, unspecified 
Chronic 
rhinitis
472.0
ICD-9 
Dx
Chronic rhinitis
J310
ICD-10 
Dx
Chronic rhinitis
Heart 
failure
428
ICD-9 
Dx
Heart failure
428.1
ICD-9 
Dx
Left heart failure
428.21
ICD-9 
Dx
Acute systolic heart failure
428.22
ICD-9 
Dx
Chronic systolic heart failure
428.23
ICD-9 
Dx
Acute on chronic systolic heart failure
428.31
ICD-9 
Dx
Acute diastolic heart failure
428.32
ICD-9 
Dx
Chronic diastolic heart failure
428.33
ICD-9 
Dx
Acute on chronic diastolic heart failure
428.41
ICD-9 
Dx
Acute combined systolic and diastolic heart failure
428.42
ICD-9 
Dx
Chronic combined systolic and diastolic heart 
failure
428.43
ICD-9 
Dx
Acute on chronic combined systolic and diastolic 
heart failure

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428.9
ICD-9 
Dx
Unspecified heart failure
398.91
ICD-9 
Dx
Rheumatic heart failure (congestive)
402.01
ICD-9 
Dx
Malignant hypertensive heart disease with heart 
failure
402.11
ICD-9 
Dx
Benign hypertensive heart disease with heart failure
402.91
ICD-9 
Dx
Hypertensive heart disease, unspecified, with heart 
failure
404.01
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.03
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.11
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and with chronic kidney 
disease stage I through stage IV, or unspecified
404.13
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and chronic kidney 
disease stage V or end stage renal disease
404.91
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.93
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and chronic kidney 
disease stage V or end stage renal disease
428.0
ICD-9 
Dx
Congestive heart failure, unspecified
428.20
ICD-9 
Dx
Unspecified systolic heart failure
428.30
ICD-9 
Dx
Unspecified diastolic heart failure
428.40
ICD-9
Dx
Unspecified combined systolic and diastolic heart 
failure

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I0981
ICD-10 
Dx
Rheumatic heart failure
I110
ICD-10 
Dx
Hypertensive heart disease with heart failure
I130
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and stage 1 through stage 4 chronic 
kidney disease, or unspecified chronic kidney 
disease
I132
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and with stage 5 chronic kidney 
disease, or end stage renal disease
I50
ICD-10 
Dx
Heart failure
I501
ICD-10 
Dx
Left ventricular failure
I5020
ICD-10 
Dx
Unspecified systolic (congestive) heart failure
I5021
ICD-10 
Dx
Acute systolic (congestive) heart failure
I5022
ICD-10 
Dx
Chronic systolic (congestive) heart failure
I5023
ICD-10 
Dx
Acute on chronic systolic (congestive) heart failure
I5030
ICD-10 
Dx
Unspecified diastolic (congestive) heart failure
I5031
ICD-10 
Dx
Acute diastolic (congestive) heart failure
I5032
ICD-10 
Dx
Chronic diastolic (congestive) heart failure
I5033
ICD-10 
Dx
Acute on chronic diastolic (congestive) heart failure
I5040
ICD-10 
Dx
Unspecified combined systolic (congestive) and 
diastolic (congestive) heart failure
I5041
ICD-10 
Dx
Acute combined systolic (congestive) and diastolic 
(congestive) heart failure
I5042
ICD-10 
Dx
Chronic combined systolic (congestive) and 
diastolic (congestive) heart failure

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I5043
ICD-10 
Dx
Acute on chronic combined systolic (congestive) 
and diastolic (congestive) heart failure
I509
ICD-10 
Dx
Heart failure, unspecified
I97130
ICD-10 
Dx
Postprocedural heart failure following cardiac 
surgery
I97131
ICD-10 
Dx
Postprocedural heart failure following other surgery
Depressio
n
296.21
ICD-9 
Dx
Major depressive disorder, single episode, mild
296.22
ICD-9 
Dx
Major depressive disorder, single episode, moderate
296.23
ICD-9 
Dx
Major depressive disorder, single episode, severe, 
without mention of psychotic behavior
296.24
ICD-9 
Dx
Major depressive disorder, single episode, severe, 
specified as with psychotic behavior
296.25
ICD-9 
Dx
Major depressive disorder, single episode, in partial 
or unspecified remission
296.26
ICD-9 
Dx
Major depressive disorder, single episode in full 
remission
296.31
ICD-9 
Dx
Major depressive disorder, recurrent episode, mild
296.32
ICD-9 
Dx
Major depressive disorder, recurrent episode, 
moderate
296.33
ICD-9 
Dx
Major depressive disorder, recurrent episode, 
severe, without mention of psychotic behavior
296.34
ICD-9 
Dx
Major depressive disorder, recurrent episode, 
severe, specified as with psychotic behavior
296.35
ICD-9 
Dx
Major depressive disorder, recurrent episode, in 
partial or unspecified remission
296.36
ICD-9 
Dx
Major depressive disorder, recurrent episode, in full 
remission
296.51
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, mild
296.52
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, moderate

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296.53
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, severe, without mention of psychotic 
behavior
296.54
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, severe, specified as with psychotic 
behavior
296.55
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, in partial or unspecified remission
296.56
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, in full remission
296.61
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, mild
296.62
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, moderate
296.63
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, severe, without mention of psychotic 
behavior
296.64
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, severe, specified as with psychotic behavior
296.65
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, in partial or unspecified remission
296.66
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, in full remission
296.7
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
unspecified
296.81
ICD-9 
Dx
Atypical manic disorder
296.82
ICD-9 
Dx
Atypical depressive disorder
296.89
ICD-9 
Dx
Other and unspecified bipolar disorders
300.4
ICD-9 
Dx
Dysthymic disorder
309.1
ICD-9 
Dx
Prolonged depressive reaction as adjustment 
reaction
311
ICD-9 
Dx
Depressive disorder, not elsewhere classified

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296.20
ICD-9 
Dx
Major depressive disorder, single episode, 
unspecified
296.30
ICD-9 
Dx
Major depressive disorder, recurrent episode, 
unspecified
296.50
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
depressed, unspecified
296.60
ICD-9 
Dx
Bipolar I disorder, most recent episode (or current) 
mixed, unspecified
296.80
ICD-9 
Dx
Bipolar disorder, unspecified
298.0
ICD-9 
Dx
Depressive type psychosis
309.0
ICD-9 
Dx
Adjustment disorder with depressed mood
F308
ICD-10 
Dx
Other manic episodes
F3130
ICD-10 
Dx
Bipolar disorder, current episode depressed, mild or 
moderate severity, unspecified
F3131
ICD-10 
Dx
Bipolar disorder, current episode depressed, mild
F3132
ICD-10 
Dx
Bipolar disorder, current episode depressed, 
moderate
F314
ICD-10 
Dx
Bipolar disorder, current episode depressed, severe, 
without psychotic features
F315
ICD-10 
Dx
Bipolar disorder, current episode depressed, severe, 
with psychotic features
F3160
ICD-10 
Dx
Bipolar disorder, current episode mixed, unspecified
F3161
ICD-10 
Dx
Bipolar disorder, current episode mixed, mild
F3162
ICD-10 
Dx
Bipolar disorder, current episode mixed, moderate
F3163
ICD-10 
Dx
Bipolar disorder, current episode mixed, severe, 
without psychotic features
F3164
ICD-10 
Dx
Bipolar disorder, current episode mixed, severe, 
with psychotic features

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F3170
ICD-10 
Dx
Bipolar disorder, currently in remission, most recent 
episode unspecified
F3171
ICD-10 
Dx
Bipolar disorder, in partial remission, most recent 
episode hypomanic
F3172
ICD-10 
Dx
Bipolar disorder, in full remission, most recent 
episode hypomanic
F3175
ICD-10 
Dx
Bipolar disorder, in partial remission, most recent 
episode depressed
F3176
ICD-10 
Dx
Bipolar disorder, in full remission, most recent 
episode depressed
F3177
ICD-10 
Dx
Bipolar disorder, in partial remission, most recent 
episode mixed
F3178
ICD-10 
Dx
Bipolar disorder, in full remission, most recent 
episode mixed
F3181
ICD-10 
Dx
Bipolar II disorder
F3189
ICD-10 
Dx
Other bipolar disorder
F319
ICD-10 
Dx
Bipolar disorder, unspecified
F320
ICD-10 
Dx
Major depressive disorder, single episode, mild
F321
ICD-10 
Dx
Major depressive disorder, single episode, moderate
F322
ICD-10 
Dx
Major depressive disorder, single episode, severe 
without psychotic features
F323
ICD-10 
Dx
Major depressive disorder, single episode, severe 
with psychotic features
F324
ICD-10 
Dx
Major depressive disorder, single episode, in partial 
remission
F325
ICD-10 
Dx
Major depressive disorder, single episode, in full 
remission
F328
ICD-10 
Dx
Other depressive episodes
F329
ICD-10 
Dx
Major depressive disorder, single episode, 
unspecified

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F330
ICD-10 
Dx
Major depressive disorder, recurrent, mild
F331
ICD-10 
Dx
Major depressive disorder, recurrent, moderate
F332
ICD-10 
Dx
Major depressive disorder, recurrent severe without 
psychotic features
F333
ICD-10 
Dx
Major depressive disorder, recurrent, severe with 
psychotic symptoms
F3340
ICD-10 
Dx
Major depressive disorder, recurrent, in remission, 
unspecified
F3341
ICD-10 
Dx
Major depressive disorder, recurrent, in partial 
remission
F3342
ICD-10 
Dx
Major depressive disorder, recurrent, in full 
remission
F338
ICD-10 
Dx
Other recurrent depressive disorders
F339
ICD-10 
Dx
Major depressive disorder, recurrent, unspecified
F341
ICD-10 
Dx
Dysthymic disorder
F4321
ICD-10 
Dx
Adjustment disorder with depressed mood
Diabetes
249.00
ICD-9
Dx
Secondary diabetes mellitus without mention of 
complication, not stated as uncontrolled, or 
unspecified
249.01
ICD-9 
Dx
Secondary diabetes mellitus without mention of 
complication, uncontrolled
249.10
ICD-9 
Dx
Secondary diabetes mellitus with ketoacidosis, not 
stated as uncontrolled, or unspecified
249.11
ICD-9 
Dx
Secondary diabetes mellitus with ketoacidosis, 
uncontrolled
249.20
ICD-9 
Dx
Secondary diabetes mellitus with hyperosmolarity, 
not stated as uncontrolled, or unspecified
249.21
ICD-9 
Dx
Secondary diabetes mellitus with hyperosmolarity, 
uncontrolled
249.30
ICD-9 
Dx
Secondary diabetes mellitus with other coma, not 
stated as uncontrolled, or unspecified

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249.31
ICD-9 
Dx
Secondary diabetes mellitus with other coma, 
uncontrolled
249.40
ICD-9 
Dx
Secondary diabetes mellitus with renal 
manifestations, not stated as uncontrolled, or 
unspecified
249.41
ICD-9 
Dx
Secondary diabetes mellitus with renal 
manifestations, uncontrolled
249.50
ICD-9 
Dx
Secondary diabetes mellitus with ophthalmic 
manifestations, not stated as uncontrolled, or 
unspecified
249.51
ICD-9 
Dx
Secondary diabetes mellitus with ophthalmic 
manifestations, uncontrolled
249.60
ICD-9 
Dx
Secondary diabetes mellitus with neurological 
manifestations, not stated as uncontrolled, or 
unspecified
249.61
ICD-9 
Dx
Secondary diabetes mellitus with neurological 
manifestations, uncontrolled
249.70
ICD-9 
Dx
Secondary diabetes mellitus with peripheral 
circulatory disorders, not stated as uncontrolled, or 
unspecified
249.71
ICD-9 
Dx
Secondary diabetes mellitus with peripheral 
circulatory disorders, uncontrolled
249.80
ICD-9 
Dx
Secondary diabetes mellitus with other specified 
manifestations, not stated as uncontrolled, or 
unspecified
249.81
ICD-9 
Dx
Secondary diabetes mellitus with other specified 
manifestations, uncontrolled
249.90
ICD-9 
Dx
Secondary diabetes mellitus with unspecified 
complication, not stated as uncontrolled, or 
unspecified
249.91
ICD-9 
Dx
Secondary diabetes mellitus with unspecified 
complication, uncontrolled
250.00
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type II or unspecified type, not stated as 
uncontrolled
250.01
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type I [juvenile type], not stated as uncontrolled

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250.02
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type II or unspecified type, uncontrolled
250.03
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type I [juvenile type], uncontrolled
250.10
ICD-9 
Dx
Diabetes with ketoacidosis, type II or unspecified 
type, not stated as uncontrolled
250.11
ICD-9 
Dx
Diabetes with ketoacidosis, type I [juvenile type], 
not stated as uncontrolled
250.12
ICD-9 
Dx
Diabetes with ketoacidosis, type II or unspecified 
type, uncontrolled
250.13
ICD-9 
Dx
Diabetes with ketoacidosis, type I [juvenile type], 
uncontrolled
250.20
ICD-9 
Dx
Diabetes with hyperosmolarity, type II or 
unspecified type, not stated as uncontrolled
250.21
ICD-9 
Dx
Diabetes with hyperosmolarity, type I [juvenile 
type], not stated as uncontrolled
250.22
ICD-9 
Dx
Diabetes with hyperosmolarity, type II or 
unspecified type, uncontrolled
250.23
ICD-9 
Dx
Diabetes with hyperosmolarity, type I [juvenile 
type], uncontrolled
250.30
ICD-9 
Dx
Diabetes with other coma, type II or unspecified 
type, not stated as uncontrolled
250.31
ICD-9 
Dx
Diabetes with other coma, type I [juvenile type], not 
stated as uncontrolled
250.32
ICD-9 
Dx
Diabetes with other coma, type II or unspecified 
type, uncontrolled
250.33
ICD-9 
Dx
Diabetes with other coma, type I [juvenile type], 
uncontrolled
250.40
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, not stated as uncontrolled
250.41
ICD-9 
Dx
Diabetes with renal manifestations, type I [juvenile 
type], not stated as uncontrolled
250.42
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, uncontrolled
250.43
ICD-9 
Dx
Diabetes with renal manifestations, type I [juvenile 
type], uncontrolled

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250.50
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type II or 
unspecified type, not stated as uncontrolled
250.51
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type I 
[juvenile type], not stated as uncontrolled
250.52
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type II or 
unspecified type, uncontrolled
250.53
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type I 
[juvenile type], uncontrolled
250.60
ICD-9 
Dx
Diabetes with neurological manifestations, type II 
or unspecified type, not stated as uncontrolled
250.61
ICD-9 
Dx
Diabetes with neurological manifestations, type I 
[juvenile type], not stated as uncontrolled
250.62
ICD-9 
Dx
Diabetes with neurological manifestations, type II 
or unspecified type, uncontrolled
250.63
ICD-9 
Dx
Diabetes with neurological manifestations, type I 
[juvenile type], uncontrolled
250.70
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, not stated as uncontrolled
250.71
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
I [juvenile type], not stated as uncontrolled
250.72
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, uncontrolled
250.73
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
I [juvenile type], uncontrolled
250.80
ICD-9 
Dx
Diabetes with other specified manifestations, type II 
or unspecified type, not stated as uncontrolled
250.81
ICD-9 
Dx
Diabetes with other specified manifestations, type I 
[juvenile type], not stated as uncontrolled
250.82
ICD-9 
Dx
Diabetes with other specified manifestations, type II 
or unspecified type, uncontrolled
250.83
ICD-9 
Dx
Diabetes with other specified manifestations, type I 
[juvenile type], uncontrolled
250.90
ICD-9 
Dx
Diabetes with unspecified complication, type II or 
unspecified type, not stated as uncontrolled
250.91
ICD-9 
Dx
Diabetes with unspecified complication, type I 
[juvenile type], not stated as uncontrolled

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250.92
ICD-9 
Dx
Diabetes with unspecified complication, type II or 
unspecified type, uncontrolled
250.93
ICD-9 
Dx
Diabetes with unspecified complication, type I 
[juvenile type], uncontrolled
251.0
ICD-9 
Dx
Hypoglycemic coma
357.2
ICD-9 
Dx
Polyneuropathy in diabetes
362.01
ICD-9 
Dx
Background diabetic retinopathy
362.02
ICD-9 
Dx
Proliferative diabetic retinopathy
362.03
ICD-9 
Dx
Nonproliferative diabetic retinopathy NOS
362.04
ICD-9 
Dx
Mild nonproliferative diabetic retinopathy
362.05
ICD-9 
Dx
Moderate nonproliferative diabetic retinopathy
362.06
ICD-9 
Dx
Severe nonproliferative diabetic retinopathy
362.07
ICD-9 
Dx
Diabetic macular edema
366.41
ICD-9 
Dx
Diabetic cataract
E0800
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
hyperosmolarity without nonketotic hyperglycemic-
hyperosmolar coma (NKHHC)
E0801
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
hyperosmolarity with coma
E0810
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
ketoacidosis without coma
E0811
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
ketoacidosis with coma
E0821
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic nephropathy
E0822
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic chronic kidney disease

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E0829
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other diabetic kidney complication
E08311
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
unspecified diabetic retinopathy with macular 
edema
E08319
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
unspecified diabetic retinopathy without macular 
edema
E08321
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
mild nonproliferative diabetic retinopathy with 
macular edema
E08329
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
mild nonproliferative diabetic retinopathy without 
macular edema
E08331
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
moderate nonproliferative diabetic retinopathy with 
macular edema
E08339
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
moderate nonproliferative diabetic retinopathy 
without macular edema
E08341
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
severe nonproliferative diabetic retinopathy with 
macular edema
E08349
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
severe nonproliferative diabetic retinopathy without 
macular edema
E08351
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
proliferative diabetic retinopathy with macular 
edema
E08359
ICD-10
Dx
Diabetes mellitus due to underlying condition with 
proliferative diabetic retinopathy without macular 
edema
E0836
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic cataract
E0839
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other diabetic ophthalmic complication
E0840
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic neuropathy, unspecified

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E0841
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic mononeuropathy
E0842
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic polyneuropathy
E0843
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic autonomic (poly)neuropathy
E0844
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic amyotrophy
E0849
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other diabetic neurological complication
E0851
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic peripheral angiopathy without gangrene
E0852
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic peripheral angiopathy with gangrene
E0859
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other circulatory complications
E08610
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic neuropathic arthropathy
E08618
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other diabetic arthropathy
E08620
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic dermatitis
E08621
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
foot ulcer
E08622
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other skin ulcer
E08628
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other skin complications
E08630
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
periodontal disease
E08638
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other oral complications
E08641
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
hypoglycemia with coma
E08649
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
hypoglycemia without coma

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E0865
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
hyperglycemia
E0869
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
other specified complication
E088
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
unspecified complications
E089
ICD-10 
Dx
Diabetes mellitus due to underlying condition 
without complications
E0900
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
hyperosmolarity without nonketotic hyperglycemic-
hyperosmolar coma (NKHHC)
E0901
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
hyperosmolarity with coma
E0910
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
ketoacidosis without coma
E0911
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
ketoacidosis with coma
E0921
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic nephropathy
E0922
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic chronic kidney disease
E0929
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other diabetic kidney complication
E09311
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
unspecified diabetic retinopathy with macular 
edema
E09319
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
unspecified diabetic retinopathy without macular 
edema
E09321
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
mild nonproliferative diabetic retinopathy with 
macular edema
E09329
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
mild nonproliferative diabetic retinopathy without 
macular edema
E09331
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
moderate nonproliferative diabetic retinopathy with 
macular edema

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E09339
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
moderate nonproliferative diabetic retinopathy 
without macular edema
E09341
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
severe nonproliferative diabetic retinopathy with 
macular edema
E09349
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
severe nonproliferative diabetic retinopathy without 
macular edema
E09351
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
proliferative diabetic retinopathy with macular 
edema
E09359
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
proliferative diabetic retinopathy without macular 
edema
E0936
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic cataract
E0939
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other diabetic ophthalmic complication
E0940
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with diabetic 
neuropathy, unspecified
E0941
ICD-10
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with diabetic 
mononeuropathy
E0942
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with diabetic 
polyneuropathy
E0943
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with diabetic autonomic 
(poly)neuropathy
E0944
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with diabetic 
amyotrophy
E0949
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
neurological complications with other diabetic 
neurological complication
E0951
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic peripheral angiopathy without gangrene

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E0952
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic peripheral angiopathy with gangrene
E0959
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other circulatory complications
E09610
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic neuropathic arthropathy
E09618
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other diabetic arthropathy
E09620
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic dermatitis
E09621
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
foot ulcer
E09622
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other skin ulcer
E09628
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other skin complications
E09630
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
periodontal disease
E09638
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other oral complications
E09641
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
hypoglycemia with coma
E09649
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
hypoglycemia without coma
E0965
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
hyperglycemia
E0969
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
other specified complication
E098
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
unspecified complications
E099
ICD-10 
Dx
Drug or chemical induced diabetes mellitus without 
complications
E1010
ICD-10 
Dx
Type 1 diabetes mellitus with ketoacidosis without 
coma
E1011
ICD-10 
Dx
Type 1 diabetes mellitus with ketoacidosis with 
coma

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E1021
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic nephropathy
E1022
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic chronic 
kidney disease
E1029
ICD-10 
Dx
Type 1 diabetes mellitus with other diabetic kidney 
complication
E10311
ICD-10 
Dx
Type 1 diabetes mellitus with unspecified diabetic 
retinopathy with macular edema
E10319
ICD-10 
Dx
Type 1 diabetes mellitus with unspecified diabetic 
retinopathy without macular edema
E10321
ICD-10 
Dx
Type 1 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema
E10329
ICD-10 
Dx
Type 1 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema
E10331
ICD-10 
Dx
Type 1 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema
E10339
ICD-10 
Dx
Type 1 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema
E10341
ICD-10 
Dx
Type 1 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema
E10349
ICD-10 
Dx
Type 1 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema
E10351
ICD-10 
Dx
Type 1 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema
E10359
ICD-10 
Dx
Type 1 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema
E1036
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic cataract
E1039
ICD-10 
Dx
Type 1 diabetes mellitus with other diabetic 
ophthalmic complication
E1040
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic neuropathy, 
unspecified
E1041
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic 
mononeuropathy

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E1042
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic 
polyneuropathy
E1043
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic autonomic 
(poly)neuropathy
E1044
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic amyotrophy
E1049
ICD-10 
Dx
Type 1 diabetes mellitus with other diabetic 
neurological complication
E1051
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic peripheral 
angiopathy without gangrene
E1052
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic peripheral 
angiopathy with gangrene
E1059
ICD-10 
Dx
Type 1 diabetes mellitus with other circulatory 
complications
E10610
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic neuropathic 
arthropathy
E10618
ICD-10 
Dx
Type 1 diabetes mellitus with other diabetic 
arthropathy
E10620
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic dermatitis
E10621
ICD-10 
Dx
Type 1 diabetes mellitus with foot ulcer
E10622
ICD-10 
Dx
Type 1 diabetes mellitus with other skin ulcer
E10628
ICD-10 
Dx
Type 1 diabetes mellitus with other skin 
complications
E10630
ICD-10 
Dx
Type 1 diabetes mellitus with periodontal disease
E10638
ICD-10 
Dx
Type 1 diabetes mellitus with other oral 
complications
E10641
ICD-10 
Dx
Type 1 diabetes mellitus with hypoglycemia with 
coma
E10649
ICD-10 
Dx
Type 1 diabetes mellitus with hypoglycemia without 
coma
E1065
ICD-10 
Dx
Type 1 diabetes mellitus with hyperglycemia

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E1069
ICD-10 
Dx
Type 1 diabetes mellitus with other specified 
complication
E108
ICD-10 
Dx
Type 1 diabetes mellitus with unspecified 
complications
E109
ICD-10 
Dx
Type 1 diabetes mellitus without complications
E1100
ICD-10 
Dx
Type 2 diabetes mellitus with hyperosmolarity 
without nonketotic hyperglycemic-hyperosmolar 
coma (NKHHC)
E1101
ICD-10 
Dx
Type 2 diabetes mellitus with hyperosmolarity with 
coma
E1121
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic nephropathy
E1122
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic chronic 
kidney disease
E1129
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic kidney 
complication
E11311
ICD-10 
Dx
Type 2 diabetes mellitus with unspecified diabetic 
retinopathy with macular edema
E11319
ICD-10 
Dx
Type 2 diabetes mellitus with unspecified diabetic 
retinopathy without macular edema
E11321
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema
E113211
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, right eye
E113212
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, left eye
E113213
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, bilateral
E113219
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, 
unspecified eye
E11329
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative
diabetic retinopathy without macular edema
E113291
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, right 
eye

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E113292
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, left 
eye
E113293
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, 
bilateral
E113299
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, 
unspecified eye
E11331
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema
E113311
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, right eye
E113312
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, left eye
E113313
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, bilateral
E113319
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, unspecified eye
E11339
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema
E113391
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, right eye
E113392
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, left eye
E113393
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, bilateral
E113399
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, unspecified eye

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E11341
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema
E113411
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, right eye
E113412
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, left eye
E113413
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, bilateral
E113419
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, unspecified eye
E11349
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema
E113491
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, right eye
E113492
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, left eye
E113493
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, bilateral
E113499
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, unspecified eye
E11351
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema
E113511
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, right eye
E113512
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, left eye
E113513
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, bilateral

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E113519
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, unspecified eye
E113521
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, right eye
E113522
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, left eye
E113523
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, bilateral
E113529
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, unspecified eye
E113531
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, right eye
E113532
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, left eye
E113533
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, bilateral
E113539
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, unspecified eye
E113541
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, right eye
E113542
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, left eye
E113543
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, bilateral

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E113549
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, unspecified eye
E113551
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, right eye
E113552
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, left eye
E113553
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, bilateral
E113559
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, unspecified eye
E11359
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema
E113591
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, right eye
E113592
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, left eye
E113593
ICD-10
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, bilateral
E113599
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, unspecified eye
E1136
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic cataract
E1137X1
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, right eye
E1137X2
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, left eye
E1137X3
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, bilateral
E1137X9
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, unspecified 
eye
E1139
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
ophthalmic complication
E1140
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic neuropathy, 
unspecified

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E1141
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic 
mononeuropathy
E1142
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic 
polyneuropathy
E1143
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic autonomic 
(poly)neuropathy
E1144
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic amyotrophy
E1149
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
neurological complication
E1151
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy without gangrene
E1152
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy with gangrene
E1159
ICD-10 
Dx
Type 2 diabetes mellitus with other circulatory 
complications
E11610
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic neuropathic 
arthropathy
E11618
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
arthropathy
E11620
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic dermatitis
E11621
ICD-10 
Dx
Type 2 diabetes mellitus with foot ulcer
E11622
ICD-10 
Dx
Type 2 diabetes mellitus with other skin ulcer
E11628
ICD-10 
Dx
Type 2 diabetes mellitus with other skin 
complications
E11630
ICD-10 
Dx
Type 2 diabetes mellitus with periodontal disease
E11638
ICD-10 
Dx
Type 2 diabetes mellitus with other oral 
complications
E11641
ICD-10 
Dx
Type 2 diabetes mellitus with hypoglycemia with 
coma
E11649
ICD-10 
Dx
Type 2 diabetes mellitus with hypoglycemia without 
coma

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E1165
ICD-10 
Dx
Type 2 diabetes mellitus with hyperglycemia
E1169
ICD-10 
Dx
Type 2 diabetes mellitus with other specified 
complication
E118
ICD-10 
Dx
Type 2 diabetes mellitus with unspecified 
complications
E119
ICD-10 
Dx
Type 2 diabetes mellitus without complications
E1300
ICD-10 
Dx
Other specified diabetes mellitus with 
hyperosmolarity without nonketotic hyperglycemic-
hyperosmolar coma (NKHHC)
E1301
ICD-10 
Dx
Other specified diabetes mellitus with 
hyperosmolarity with coma
E1310
ICD-10 
Dx
Other specified diabetes mellitus with ketoacidosis 
without coma
E1311
ICD-10 
Dx
Other specified diabetes mellitus with ketoacidosis 
with coma
E1321
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
nephropathy
E1322
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
chronic kidney disease
E1329
ICD-10 
Dx
Other specified diabetes mellitus with other diabetic 
kidney complication
E13311
ICD-10 
Dx
Other specified diabetes mellitus with unspecified 
diabetic retinopathy with macular edema
E13319
ICD-10 
Dx
Other specified diabetes mellitus with unspecified 
diabetic retinopathy without macular edema
E13321
ICD-10 
Dx
Other specified diabetes mellitus with mild 
nonproliferative diabetic retinopathy with macular 
edema
E13329
ICD-10 
Dx
Other specified diabetes mellitus with mild 
nonproliferative diabetic retinopathy without 
macular edema
E13331
ICD-10 
Dx
Other specified diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema

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E13339
ICD-10 
Dx
Other specified diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema
E13341
ICD-10 
Dx
Other specified diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema
E13349
ICD-10 
Dx
Other specified diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema
E13351
ICD-10 
Dx
Other specified diabetes mellitus with proliferative 
diabetic retinopathy with macular edema
E13359
ICD-10 
Dx
Other specified diabetes mellitus with proliferative 
diabetic retinopathy without macular edema
E1336
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
cataract
E1339
ICD-10 
Dx
Other specified diabetes mellitus with other diabetic 
ophthalmic complication
E1340
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
neuropathy, unspecified
E1341
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
mononeuropathy
E1342
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
polyneuropathy
E1343
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
autonomic (poly)neuropathy
E1344
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
amyotrophy
E1349
ICD-10 
Dx
Other specified diabetes mellitus with other diabetic 
neurological complication
E1351
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
peripheral angiopathy without gangrene
E1352
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
peripheral angiopathy with gangrene
E1359
ICD-10 
Dx
Other specified diabetes mellitus with other 
circulatory complications
E13610
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
neuropathic arthropathy

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E13618
ICD-10 
Dx
Other specified diabetes mellitus with other diabetic 
arthropathy
E13620
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
dermatitis
E13621
ICD-10 
Dx
Other specified diabetes mellitus with foot ulcer
E13622
ICD-10 
Dx
Other specified diabetes mellitus with other skin 
ulcer
E13628
ICD-10 
Dx
Other specified diabetes mellitus with other skin
complications
E13630
ICD-10 
Dx
Other specified diabetes mellitus with periodontal 
disease
E13638
ICD-10 
Dx
Other specified diabetes mellitus with other oral 
complications
E13641
ICD-10 
Dx
Other specified diabetes mellitus with 
hypoglycemia with coma
E13649
ICD-10 
Dx
Other specified diabetes mellitus with 
hypoglycemia without coma
E1365
ICD-10 
Dx
Other specified diabetes mellitus with 
hyperglycemia
E1369
ICD-10 
Dx
Other specified diabetes mellitus with other 
specified complication
E138
ICD-10 
Dx
Other specified diabetes mellitus with unspecified 
complications
E139
ICD-10 
Dx
Other specified diabetes mellitus without 
complications
Dyspnea
786.09
ICD-9 
Dx
Dyspnea and respiratory abnormalities, other 
(respiratory distress/insufficiency)
786.05
ICD-9 
Dx
Shortness of breath
786.07
ICD-9 
Dx
Wheezing
786.1
ICD-9 
Dx
Stridor
R0689
ICD-10 
Dx
Other abnormalities of breathing

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R0600
ICD-10 
Dx
Dyspnea, unspecified
R0602
ICD-10 
Dx
Shortness of breath
R0609
ICD-10 
Dx
Other forms of dyspnea
R061
ICD-10 
Dx
Stridor
R062
ICD-10 
Dx
Wheezing
Hypertens
ion
362.11
ICD-9 
Dx
Hypertensive retinopathy
401.0
ICD-9 
Dx
Essential hypertension, malignant
401.1
ICD-9 
Dx
Essential hypertension, benign
401.9
ICD-9 
Dx
Unspecified essential hypertension
402.00
ICD-9 
Dx
Malignant hypertensive heart disease without heart 
failure
402.01
ICD-9 
Dx
Malignant hypertensive heart disease with heart 
failure
402.10
ICD-9 
Dx
Benign hypertensive heart disease without heart 
failure
402.11
ICD-9 
Dx
Benign hypertensive heart disease with heart failure
402.90
ICD-9 
Dx
Unspecified hypertensive heart disease without 
heart failure
402.91
ICD-9 
Dx
Hypertensive heart disease, unspecified, with heart 
failure
403.00
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.01
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage V or end stage 
renal disease

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403.10
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage I through stage IV, or 
unspecified
403.11
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage V or end stage renal 
disease
403.90
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.91
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage V or end stage 
renal disease
404.00
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.01
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.02
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.03
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.10
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.11
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and with chronic kidney 
disease stage I through stage IV, or unspecified
404.12
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.13
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and chronic kidney 
disease stage V or end stage renal disease

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404.90
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.91
ICD-9 
Dx
Hypertensive heart and chronic kidney disease,
unspecified, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.92
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.93
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and chronic kidney 
disease stage V or end stage renal disease
405.01
ICD-9 
Dx
Secondary renovascular hypertension, malignant
405.09
ICD-9 
Dx
Other secondary hypertension, malignant
405.11
ICD-9 
Dx
Secondary renovascular hypertension, benign
405.19
ICD-9 
Dx
Other secondary hypertension, benign
405.91
ICD-9 
Dx
Secondary renovascular hypertension, unspecified
405.99
ICD-9 
Dx
Other secondary hypertension, unspecified
437.2
ICD-9 
Dx
Hypertensive encephalopathy
997.91
ICD-9 
Dx
Hypertension
H35031
ICD-10 
Dx
Hypertensive retinopathy, right eye
H35032
ICD-10 
Dx
Hypertensive retinopathy, left eye
H35033
ICD-10 
Dx
Hypertensive retinopathy, bilateral
H35039
ICD-10 
Dx
Hypertensive retinopathy, unspecified eye

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I10
ICD-10 
Dx
Essential (primary) hypertension
I110
ICD-10 
Dx
Hypertensive heart disease with heart failure
I119
ICD-10 
Dx
Hypertensive heart disease without heart failure
I120
ICD-10 
Dx
Hypertensive chronic kidney disease with stage 5 
chronic kidney disease or end stage renal disease
I129
ICD-10 
Dx
Hypertensive chronic kidney disease with stage 1 
through stage 4 chronic kidney disease, or 
unspecified chronic kidney disease
I130
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and stage 1 through stage 4 chronic 
kidney disease, or unspecified chronic kidney 
disease
I1310
ICD-10 
Dx
Hypertensive heart and chronic kidney disease 
without heart failure, with stage 1 through stage 4 
chronic kidney disease, or unspecified chronic 
kidney disease
I1311
ICD-10 
Dx
Hypertensive heart and chronic kidney disease 
without heart failure, with stage 5 chronic kidney 
disease, or end stage renal disease
I132
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and with stage 5 chronic kidney 
disease, or end stage renal disease
I150
ICD-10 
Dx
Renovascular hypertension
I151
ICD-10 
Dx
Hypertension secondary to other renal disorders
I152
ICD-10 
Dx
Hypertension secondary to endocrine disorders
I158
ICD-10 
Dx
Other secondary hypertension
I159
ICD-10 
Dx
Secondary hypertension, unspecified
I160
ICD-10 
Dx
Hypertensive urgency

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I161
ICD-10 
Dx
Hypertensive emergency
I169
ICD-10 
Dx
Hypertensive crisis, unspecified
I674
ICD-10 
Dx
Hypertensive encephalopathy
I973
ICD-10 
Dx
Postprocedural hypertension
N262
ICD-10 
Dx
Page kidney
Ischemic 
heart 
disease
410.01
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
initial episode of care
410.02
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
subsequent episode of care
410.11
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
initial episode of care
410.12
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
subsequent episode of care
410.21
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
initial episode of care
410.22
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
subsequent episode of care
410.31
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
initial episode of care
410.32
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
subsequent episode of care
410.41
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
initial episode of care
410.42
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
subsequent episode of care
410.51
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
initial episode of care
410.52
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
subsequent episode of care
410.61
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, initial episode of care

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410.62
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, subsequent episode of care
410.71
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, initial episode of care
410.72
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, subsequent episode of care
410.81
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
initial episode of care
410.82
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
subsequent episode of care
410.91
ICD-9 
Dx
Acute myocardial infarction, unspecified site, initial 
episode of care
410.92
ICD-9 
Dx
Acute myocardial infarction, unspecified site, 
subsequent episode of care
411.1
ICD-9 
Dx
Intermediate coronary syndrome
411.81
ICD-9 
Dx
Acute coronary occlusion without myocardial 
infarction
411.89
ICD-9 
Dx
Other acute and subacute form of ischemic heart 
disease
412
ICD-9 
Dx
Old myocardial infarction
413.1
ICD-9 
Dx
Prinzmetal angina
413.9
ICD-9 
Dx
Other and unspecified angina pectoris
414.01
ICD-9 
Dx
Coronary atherosclerosis of native coronary artery
414.02
ICD-9 
Dx
Coronary atherosclerosis of autologous vein bypass 
graft
414.03
ICD-9 
Dx
Coronary atherosclerosis of nonautologous 
biological bypass graft
414.04
ICD-9 
Dx
Coronary atherosclerosis of artery bypass graft
414.05
ICD-9 
Dx
Coronary atherosclerosis of unspecified type of 
bypass graft

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414.06
ICD-9 
Dx
Coronary atherosclerosis, of native coronary artery 
of transplanted heart
414.07
ICD-9 
Dx
Coronary atherosclerosis, of bypass graft (artery) 
(vein) of transplanted heart
414.11
ICD-9 
Dx
Aneurysm of coronary vessels
414.12
ICD-9 
Dx
Dissection of coronary artery
414.19
ICD-9 
Dx
Other aneurysm of heart
414.2
ICD-9 
Dx
Chronic total occlusion of coronary artery
414.3
ICD-9 
Dx
Coronary atherosclerosis due to lipid rich plaque
414.4
ICD-9 
Dx
Coronary atherosclerosis due to calcified coronary 
lesion
414.8
ICD-9 
Dx
Other specified forms of chronic ischemic heart 
disease
414.9
ICD-9 
Dx
Unspecified chronic ischemic heart disease
410.00
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
episode of care unspecified
410.10
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
episode of care unspecified
410.20
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
episode of care unspecified
410.30
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
episode of care unspecified
410.40
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
episode of care unspecified
410.50
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
episode of care unspecified
410.60
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, episode of care unspecified
410.70
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, episode of care unspecified

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410.80
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
episode of care unspecified
410.90
ICD-9 
Dx
Acute myocardial infarction, unspecified site, 
episode of care unspecified
411.0
ICD-9 
Dx
Postmyocardial infarction syndrome
413.0
ICD-9 
Dx
Angina decubitus
414.00
ICD-9 
Dx
Coronary atherosclerosis of unspecified type of 
vessel, native or graft
414.10
ICD-9 
Dx
Aneurysm of heart
429.71
ICD-9 
Dx
Acquired cardiac septal defect following myocardial 
infarction
429.79
ICD-9 
Dx
Other certain sequelae of myocardial infarction, not 
elsewhere classified
I200
ICD-10 
Dx
Unstable angina
I201
ICD-10 
Dx
Angina pectoris with documented spasm
I208
ICD-10 
Dx
Other forms of angina pectoris
I209
ICD-10 
Dx
Angina pectoris, unspecified
I2101
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left main coronary artery
I2102
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left anterior descending coronary artery
I2109
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other coronary artery of anterior wall
I2111
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving right coronary artery
I2119
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other coronary artery of inferior wall
I2121
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left circumflex coronary artery

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I2129
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other sites
I213
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction of 
unspecified site
I214
ICD-10 
Dx
Non-ST elevation (NSTEMI) myocardial infarction
I220
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of anterior wall
I221
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of inferior wall
I222
ICD-10 
Dx
Subsequent non-ST elevation (NSTEMI) 
myocardial infarction
I228
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of other sites
I229
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of unspecified site
I230
ICD-10 
Dx
Hemopericardium as current complication following 
acute myocardial infarction
I231
ICD-10 
Dx
Atrial septal defect as current complication 
following acute myocardial infarction
I232
ICD-10 
Dx
Ventricular septal defect as current complication 
following acute myocardial infarction
I233
ICD-10 
Dx
Rupture of cardiac wall without hemopericardium 
as current complication following acute myocardial 
infarction
I234
ICD-10 
Dx
Rupture of chordae tendineae as current 
complication following acute myocardial infarction
I235
ICD-10 
Dx
Rupture of papillary muscle as current complication 
following acute myocardial infarction
I236
ICD-10 
Dx
Thrombosis of atrium, auricular appendage, and 
ventricle as current complications following acute 
myocardial infarction
I240
ICD-10 
Dx
Acute coronary thrombosis not resulting in 
myocardial infarction
I241
ICD-10 
Dx
Dressler's syndrome

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I248
ICD-10 
Dx
Other forms of acute ischemic heart disease
I249
ICD-10 
Dx
Acute ischemic heart disease, unspecified
I2510
ICD-10 
Dx
Atherosclerotic heart disease of native coronary 
artery without angina pectoris
I25110
ICD-10 
Dx
Atherosclerotic heart disease of native coronary 
artery with unstable angina pectoris
I25111
ICD-10 
Dx
Atherosclerotic heart disease of native coronary 
artery with angina pectoris with documented spasm
I25118
ICD-10 
Dx
Atherosclerotic heart disease of native coronary 
artery with other forms of angina pectoris
I25119
ICD-10 
Dx
Atherosclerotic heart disease of native coronary 
artery with unspecified angina pectoris
I252
ICD-10 
Dx
Old myocardial infarction
I253
ICD-10 
Dx
Aneurysm of heart
I2541
ICD-10 
Dx
Coronary artery aneurysm
I2542
ICD-10 
Dx
Coronary artery dissection
I255
ICD-10 
Dx
Ischemic cardiomyopathy
I256
ICD-10 
Dx
Silent myocardial ischemia
I25700
ICD-10 
Dx
Atherosclerosis of coronary artery bypass graft(s), 
unspecified, with unstable angina pectoris
I25701
ICD-10 
Dx
Atherosclerosis of coronary artery bypass graft(s), 
unspecified, with angina pectoris with documented 
spasm
I25708
ICD-10 
Dx
Atherosclerosis of coronary artery bypass graft(s), 
unspecified, with other forms of angina pectoris
I25709
ICD-10 
Dx
Atherosclerosis of coronary artery bypass graft(s), 
unspecified, with unspecified angina pectoris
I25710
ICD-10 
Dx
Atherosclerosis of autologous vein coronary artery 
bypass graft(s) with unstable angina pectoris

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I25711
ICD-10 
Dx
Atherosclerosis of autologous vein coronary artery 
bypass graft(s) with angina pectoris with 
documented spasm
I25718
ICD-10 
Dx
Atherosclerosis of autologous vein coronary artery 
bypass graft(s) with other forms of angina pectoris
I25719
ICD-10 
Dx
Atherosclerosis of autologous vein coronary artery 
bypass graft(s) with unspecified angina pectoris
I25720
ICD-10 
Dx
Atherosclerosis of autologous artery coronary artery 
bypass graft(s) with unstable angina pectoris
I25721
ICD-10 
Dx
Atherosclerosis of autologous artery coronary artery 
bypass graft(s) with angina pectoris with 
documented spasm
I25728
ICD-10 
Dx
Atherosclerosis of autologous artery coronary artery 
bypass graft(s) with other forms of angina pectoris
I25729
ICD-10 
Dx
Atherosclerosis of autologous artery coronary artery 
bypass graft(s) with unspecified angina pectoris
I25730
ICD-10 
Dx
Atherosclerosis of nonautologous biological 
coronary artery bypass graft(s) with unstable angina 
pectoris
I25731
ICD-10 
Dx
Atherosclerosis of nonautologous biological 
coronary artery bypass graft(s) with angina pectoris 
with documented spasm
I25738
ICD-10 
Dx
Atherosclerosis of nonautologous biological 
coronary artery bypass graft(s) with other forms of 
angina pectoris
I25739
ICD-10 
Dx
Atherosclerosis of nonautologous biological 
coronary artery bypass graft(s) with unspecified 
angina pectoris
I25750
ICD-10 
Dx
Atherosclerosis of native coronary artery of 
transplanted heart with unstable angina
I25751
ICD-10 
Dx
Atherosclerosis of native coronary artery of 
transplanted heart with angina pectoris with 
documented spasm
I25758
ICD-10 
Dx
Atherosclerosis of native coronary artery of 
transplanted heart with other forms of angina 
pectoris
I25759
ICD-10 
Dx
Atherosclerosis of native coronary artery of 
transplanted heart with unspecified angina pectoris

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I25760
ICD-10 
Dx
Atherosclerosis of bypass graft of coronary artery of 
transplanted heart with unstable angina
I25761
ICD-10 
Dx
Atherosclerosis of bypass graft of coronary artery of 
transplanted heart with angina pectoris with 
documented spasm
I25768
ICD-10 
Dx
Atherosclerosis of bypass graft of coronary artery of 
transplanted heart with other forms of angina 
pectoris
I25769
ICD-10 
Dx
Atherosclerosis of bypass graft of coronary artery of 
transplanted heart with unspecified angina pectoris
I25790
ICD-10 
Dx
Atherosclerosis of other coronary artery bypass 
graft(s) with unstable angina pectoris
I25791
ICD-10 
Dx
Atherosclerosis of other coronary artery bypass 
graft(s) with angina pectoris with documented 
spasm
I25798
ICD-10 
Dx
Atherosclerosis of other coronary artery bypass 
graft(s) with other forms of angina pectoris
I25799
ICD-10 
Dx
Atherosclerosis of other coronary artery bypass 
graft(s) with unspecified angina pectoris
I25810
ICD-10 
Dx
Atherosclerosis of coronary artery bypass graft(s) 
without angina pectoris
I25811
ICD-10 
Dx
Atherosclerosis of native coronary artery of 
transplanted heart without angina pectoris
I25812
ICD-10 
Dx
Atherosclerosis of bypass graft of coronary artery of 
transplanted heart without angina pectoris
I2582
ICD-10 
Dx
Chronic total occlusion of coronary artery
I2583
ICD-10 
Dx
Coronary atherosclerosis due to lipid rich plaque
I2584
ICD-10 
Dx
Coronary atherosclerosis due to calcified coronary 
lesion
I2589
ICD-10 
Dx
Other forms of chronic ischemic heart disease
I259
ICD-10 
Dx
Chronic ischemic heart disease, unspecified
Metabolic 
syndrome
278.00
ICD-9 
Dx
Obesity, unspecified

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278.01
ICD-9 
Dx
Morbid obesity
278.02
ICD-9 
Dx
Overweight
278.1
ICD-9 
Dx
Localized adiposity
783.1
ICD-9 
Dx
Abnormal weight gain
E65
ICD-10 
Dx
Localized adiposity
E6601
ICD-10 
Dx
Morbid (severe) obesity due to excess calories
E6609
ICD-10 
Dx
Other obesity due to excess calories
E663
ICD-10 
Dx
Overweight
E668
ICD-10 
Dx
Other obesity
E669
ICD-10 
Dx
Obesity, unspecified
R635
ICD-10 
Dx
Abnormal weight gain
272.0
ICD-9 
Dx
Pure hypercholesterolemia
272.1
ICD-9 
Dx
Pure hyperglyceridemia
272.2
ICD-9 
Dx
Mixed hyperlipidemia
272.4
ICD-9 
Dx
Other and unspecified hyperlipidemia
E780
ICD-10 
Dx
Pure hypercholesterolemia
E7800
ICD-10 
Dx
Pure hypercholesterolemia, unspecified
E781
ICD-10 
Dx
Pure hyperglyceridemia

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E782
ICD-10 
Dx
Mixed hyperlipidemia
E784
ICD-10 
Dx
Other hyperlipidemia
E785
ICD-10 
Dx
Hyperlipidemia, unspecified
362.11
ICD-9 
Dx
Hypertensive retinopathy
401.0
ICD-9 
Dx
Essential hypertension, malignant
401.1
ICD-9 
Dx
Essential hypertension, benign
401.9
ICD-9 
Dx
Unspecified essential hypertension
402.00
ICD-9 
Dx
Malignant hypertensive heart disease without heart 
failure
402.01
ICD-9 
Dx
Malignant hypertensive heart disease with heart 
failure
402.10
ICD-9 
Dx
Benign hypertensive heart disease without heart 
failure
402.11
ICD-9 
Dx
Benign hypertensive heart disease with heart failure
402.90
ICD-9 
Dx
Unspecified hypertensive heart disease without 
heart failure
402.91
ICD-9 
Dx
Hypertensive heart disease, unspecified, with heart 
failure
403.00
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.01
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage V or end stage 
renal disease
403.10
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage I through stage IV, or 
unspecified
403.11
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage V or end stage renal 
disease

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403.90
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.91
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage V or end stage 
renal disease
404.00
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.01
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.02
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.03
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.10
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.11
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and with chronic kidney 
disease stage I through stage IV, or unspecified
404.12
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.13
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and chronic kidney 
disease stage V or end stage renal disease
404.90
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified

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404.91
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.92
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.93
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and chronic kidney 
disease stage V or end stage renal disease
405.01
ICD-9 
Dx
Secondary renovascular hypertension, malignant
405.09
ICD-9 
Dx
Other secondary hypertension, malignant
405.11
ICD-9 
Dx
Secondary renovascular hypertension, benign
405.19
ICD-9 
Dx
Other secondary hypertension, benign
405.91
ICD-9 
Dx
Secondary renovascular hypertension, unspecified
405.99
ICD-9 
Dx
Other secondary hypertension, unspecified
437.2
ICD-9 
Dx
Hypertensive encephalopathy
997.91
ICD-9 
Dx
Hypertension
H35031
ICD-10 
Dx
Hypertensive retinopathy, right eye
H35032
ICD-10 
Dx
Hypertensive retinopathy, left eye
H35033
ICD-10 
Dx
Hypertensive retinopathy, bilateral
H35039
ICD-10 
Dx
Hypertensive retinopathy, unspecified eye
I10
ICD-10 
Dx
Essential (primary) hypertension
I110
ICD-10 
Dx
Hypertensive heart disease with heart failure

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I119
ICD-10 
Dx
Hypertensive heart disease without heart failure
I120
ICD-10 
Dx
Hypertensive chronic kidney disease with stage 5 
chronic kidney disease or end stage renal disease
I129
ICD-10 
Dx
Hypertensive chronic kidney disease with stage 1 
through stage 4 chronic kidney disease, or 
unspecified chronic kidney disease
I130
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and stage 1 through stage 4 chronic 
kidney disease, or unspecified chronic kidney 
disease
I1310
ICD-10 
Dx
Hypertensive heart and chronic kidney disease 
without heart failure, with stage 1 through stage 4 
chronic kidney disease, or unspecified chronic 
kidney disease
I1311
ICD-10 
Dx
Hypertensive heart and chronic kidney disease
without heart failure, with stage 5 chronic kidney 
disease, or end stage renal disease
I132
ICD-10 
Dx
Hypertensive heart and chronic kidney disease with 
heart failure and with stage 5 chronic kidney 
disease, or end stage renal disease
I150
ICD-10 
Dx
Renovascular hypertension
I151
ICD-10 
Dx
Hypertension secondary to other renal disorders
I152
ICD-10 
Dx
Hypertension secondary to endocrine disorders
I158
ICD-10 
Dx
Other secondary hypertension
I159
ICD-10 
Dx
Secondary hypertension, unspecified
I160
ICD-10 
Dx
Hypertensive urgency
I161
ICD-10 
Dx
Hypertensive emergency
I169
ICD-10 
Dx
Hypertensive crisis, unspecified

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I674
ICD-10 
Dx
Hypertensive encephalopathy
I973
ICD-10 
Dx
Postprocedural hypertension
N262
ICD-10 
Dx
Page kidney
250.00
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type II or unspecified type, not stated as 
uncontrolled
250.02
ICD-9 
Dx
Diabetes mellitus without mention of complication, 
type II or unspecified type, uncontrolled
250.10
ICD-9 
Dx
Diabetes with ketoacidosis, type II or unspecified 
type, not stated as uncontrolled
250.12
ICD-9 
Dx
Diabetes with ketoacidosis, type II or unspecified 
type, uncontrolled
250.20
ICD-9 
Dx
Diabetes with hyperosmolarity, type II or 
unspecified type, not stated as uncontrolled
250.22
ICD-9 
Dx
Diabetes with hyperosmolarity, type II or 
unspecified type, uncontrolled
250.30
ICD-9 
Dx
Diabetes with other coma, type II or unspecified 
type, not stated as uncontrolled
250.32
ICD-9 
Dx
Diabetes with other coma, type II or unspecified 
type, uncontrolled
250.40
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, not stated as uncontrolled
250.42
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, uncontrolled
250.50
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type II or 
unspecified type, not stated as uncontrolled
250.52
ICD-9 
Dx
Diabetes with ophthalmic manifestations, type II or 
unspecified type, uncontrolled
250.60
ICD-9 
Dx
Diabetes with neurological manifestations, type II 
or unspecified type, not stated as uncontrolled
250.62
ICD-9 
Dx
Diabetes with neurological manifestations, type II 
or unspecified type, uncontrolled
250.70
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, not stated as uncontrolled

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250.72
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, uncontrolled
250.80
ICD-9 
Dx
Diabetes with other specified manifestations, type II 
or unspecified type, not stated as uncontrolled
250.82
ICD-9 
Dx
Diabetes with other specified manifestations, type II 
or unspecified type, uncontrolled
250.90
ICD-9 
Dx
Diabetes with unspecified complication, type II or 
unspecified type, not stated as uncontrolled
250.92
ICD-9 
Dx
Diabetes with unspecified complication, type II or 
unspecified type, uncontrolled
790.21
ICD-9 
Dx
Impaired fasting glucose
790.22
ICD-9 
Dx
Impaired glucose tolerance test (oral)
790.29
ICD-9 
Dx
Other abnormal glucose
E1100
ICD-10 
Dx
Type 2 diabetes mellitus with hyperosmolarity 
without nonketotic hyperglycemic-hyperosmolar 
coma (NKHHC)
E1101
ICD-10 
Dx
Type 2 diabetes mellitus with hyperosmolarity with 
coma
E1121
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic nephropathy
E1122
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic chronic 
kidney disease
E1129
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic kidney 
complication
E11311
ICD-10 
Dx
Type 2 diabetes mellitus with unspecified diabetic 
retinopathy with macular edema
E11319
ICD-10
Dx
Type 2 diabetes mellitus with unspecified diabetic 
retinopathy without macular edema
E11321
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema
E113211
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, right eye
E113212
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, left eye

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E113213
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, bilateral
E113219
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy with macular edema, 
unspecified eye
E11329
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative
diabetic retinopathy without macular edema
E113291
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, right 
eye
E113292
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, left 
eye
E113293
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, 
bilateral
E113299
ICD-10 
Dx
Type 2 diabetes mellitus with mild nonproliferative 
diabetic retinopathy without macular edema, 
unspecified eye
E11331
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema
E113311
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, right eye
E113312
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, left eye
E113313
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, bilateral
E113319
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy with macular 
edema, unspecified eye
E11339
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema

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E113391
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, right eye
E113392
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, left eye
E113393
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, bilateral
E113399
ICD-10 
Dx
Type 2 diabetes mellitus with moderate 
nonproliferative diabetic retinopathy without 
macular edema, unspecified eye
E11341
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema
E113411
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, right eye
E113412
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, left eye
E113413
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, bilateral
E113419
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy with macular 
edema, unspecified eye
E11349
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema
E113491
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, right eye
E113492
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, left eye
E113493
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, bilateral

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E113499
ICD-10 
Dx
Type 2 diabetes mellitus with severe 
nonproliferative diabetic retinopathy without 
macular edema, unspecified eye
E11351
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema
E113511
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, right eye
E113512
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, left eye
E113513
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, bilateral
E113519
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with macular edema, unspecified eye
E113521
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, right eye
E113522
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, left eye
E113523
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment
involving the macula, bilateral
E113529
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment 
involving the macula, unspecified eye
E113531
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, right eye
E113532
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, left eye
E113533
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, bilateral
E113539
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with traction retinal detachment not 
involving the macula, unspecified eye

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E113541
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, right eye
E113542
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, left eye
E113543
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, bilateral
E113549
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy with combined traction retinal 
detachment and rhegmatogenous retinal 
detachment, unspecified eye
E113551
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, right eye
E113552
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, left eye
E113553
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, bilateral
E113559
ICD-10 
Dx
Type 2 diabetes mellitus with stable proliferative 
diabetic retinopathy, unspecified eye
E11359
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema
E113591
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, right eye
E113592
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, left eye
E113593
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, bilateral
E113599
ICD-10 
Dx
Type 2 diabetes mellitus with proliferative diabetic 
retinopathy without macular edema, unspecified eye
E1136
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic cataract
E1137X1
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, right eye

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E1137X2
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, left eye
E1137X3
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, bilateral
E1137X9
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic macular 
edema, resolved following treatment, unspecified 
eye
E1139
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
ophthalmic complication
E1140
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic neuropathy, 
unspecified
E1141
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic 
mononeuropathy
E1142
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic 
polyneuropathy
E1143
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic autonomic 
(poly)neuropathy
E1144
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic amyotrophy
E1149
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
neurological complication
E1151
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy without gangrene
E1152
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy with gangrene
E1159
ICD-10 
Dx
Type 2 diabetes mellitus with other circulatory 
complications
E11610
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic neuropathic 
arthropathy
E11618
ICD-10 
Dx
Type 2 diabetes mellitus with other diabetic 
arthropathy
E11620
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic dermatitis
E11621
ICD-10 
Dx
Type 2 diabetes mellitus with foot ulcer
E11622
ICD-10 
Dx
Type 2 diabetes mellitus with other skin ulcer

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E11628
ICD-10 
Dx
Type 2 diabetes mellitus with other skin 
complications
E11630
ICD-10 
Dx
Type 2 diabetes mellitus with periodontal disease
E11638
ICD-10 
Dx
Type 2 diabetes mellitus with other oral 
complications
E11641
ICD-10 
Dx
Type 2 diabetes mellitus with hypoglycemia with 
coma
E11649
ICD-10 
Dx
Type 2 diabetes mellitus with hypoglycemia without 
coma
E1165
ICD-10 
Dx
Type 2 diabetes mellitus with hyperglycemia
E1169
ICD-10 
Dx
Type 2 diabetes mellitus with other specified 
complication
E118
ICD-10 
Dx
Type 2 diabetes mellitus with unspecified 
complications
E119
ICD-10 
Dx
Type 2 diabetes mellitus without complications
R7301
ICD-10 
Dx
Impaired fasting glucose
R7302
ICD-10 
Dx
Impaired glucose tolerance (oral)
R7303
ICD-10 
Dx
Prediabetes
R7309
ICD-10 
Dx
Other abnormal glucose
Myocardia
l 
infarction
410.01
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
initial episode of care
410.02
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
subsequent episode of care
410.11
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
initial episode of care
410.12
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
subsequent episode of care
410.21
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
initial episode of care

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410.22
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
subsequent episode of care
410.31
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
initial episode of care
410.32
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
subsequent episode of care
410.41
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
initial episode of care
410.42
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
subsequent episode of care
410.51
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
initial episode of care
410.52
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
subsequent episode of care
410.61
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, initial episode of care
410.62
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, subsequent episode of care
410.71
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, initial episode of care
410.72
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, subsequent episode of care
410.81
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
initial episode of care
410.82
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
subsequent episode of care
410.91
ICD-9 
Dx
Acute myocardial infarction, unspecified site, initial 
episode of care
410.92
ICD-9 
Dx
Acute myocardial infarction, unspecified site, 
subsequent episode of care
412
ICD-9 
Dx
Old myocardial infarction
410.00
ICD-9 
Dx
Acute myocardial infarction of anterolateral wall, 
episode of care unspecified
410.10
ICD-9 
Dx
Acute myocardial infarction of other anterior wall, 
episode of care unspecified

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410.20
ICD-9 
Dx
Acute myocardial infarction of inferolateral wall, 
episode of care unspecified
410.30
ICD-9 
Dx
Acute myocardial infarction of inferoposterior wall, 
episode of care unspecified
410.40
ICD-9 
Dx
Acute myocardial infarction of other inferior wall, 
episode of care unspecified
410.50
ICD-9 
Dx
Acute myocardial infarction of other lateral wall, 
episode of care unspecified
410.60
ICD-9 
Dx
Acute myocardial infarction, true posterior wall 
infarction, episode of care unspecified
410.70
ICD-9 
Dx
Acute myocardial infarction, subendocardial 
infarction, episode of care unspecified
410.80
ICD-9 
Dx
Acute myocardial infarction of other specified sites, 
episode of care unspecified
410.90
ICD-9 
Dx
Acute myocardial infarction, unspecified site, 
episode of care unspecified
411.0
ICD-9 
Dx
Postmyocardial infarction syndrome
429.71
ICD-9 
Dx
Acquired cardiac septal defect
429.79
ICD-9 
Dx
Other certain sequelae of myocardial infarction, not 
elsewhere classified
I2101
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left main coronary artery
I2102
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left anterior descending coronary artery
I2109
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other coronary artery of anterior wall
I2111
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving right coronary artery
I2119
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other coronary artery of inferior wall
I2121
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving left circumflex coronary artery
I2129
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction 
involving other sites

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I213
ICD-10 
Dx
ST elevation (STEMI) myocardial infarction of 
unspecified site
I214
ICD-10 
Dx
Non-ST elevation (NSTEMI) myocardial infarction
I220
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of anterior wall
I221
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of inferior wall
I222
ICD-10 
Dx
Subsequent non-ST elevation (NSTEMI) 
myocardial infarction
I228
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of other sites
I229
ICD-10 
Dx
Subsequent ST elevation (STEMI) myocardial 
infarction of unspecified site
I230
ICD-10 
Dx
Hemopericardium as current complication following 
acute myocardial infarction
I231
ICD-10 
Dx
Atrial septal defect as current complication 
following acute myocardial infarction
I232
ICD-10 
Dx
Ventricular septal defect as current complication 
following acute myocardial infarction
I233
ICD-10 
Dx
Rupture of cardiac wall without hemopericardium 
as current complication following acute myocardial 
infarction
I234
ICD-10 
Dx
Rupture of chordae tendineae as current 
complication following acute myocardial infarction
I235
ICD-10 
Dx
Rupture of papillary muscle as current complication 
following acute myocardial infarction
I236
ICD-10 
Dx
Thrombosis of atrium, auricular appendage, and 
ventricle as current complications following acute 
myocardial infarction
I252
ICD-10 
Dx
Old myocardial infarction
Osteoporo
sis
733.0
ICD-9 
Dx
Osteoporosis 
733.00
ICD-9 
Dx
Unspecified osteoporosis

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733.01
ICD-9 
Dx
Senile osteoporosis
733.02
ICD-9 
Dx
Idiopathic osteoporosis
733.03
ICD-9 
Dx
Disuse osteoporosis
733.09
ICD-9 
Dx
Other osteoporosis
M80
ICD-10 
Dx
Osteoporosis with current pathological fracture
M8000XA
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, initial encounter for 
fracture
M8000XD
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with routine healing
M8000XG
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with delayed healing
M8000XK
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with nonunion
M8000XP
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with malunion
M8000XS
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified site, sequela
M80011A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, initial encounter for fracture
M80011D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with routine healing
M80011G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with delayed healing
M80011K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with nonunion

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M80011P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with malunion
M80011S
ICD-10
Dx
Age-related osteoporosis with current pathological 
fracture, right shoulder, sequela
M80012A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, initial encounter for fracture
M80012D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with routine healing
M80012G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with delayed healing
M80012K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with nonunion
M80012P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with malunion
M80012S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left shoulder, sequela
M80019A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, initial encounter for 
fracture
M80019D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with routine healing
M80019G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with delayed healing
M80019K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with nonunion
M80019P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with malunion
M80019S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified shoulder, sequela

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M80021A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, initial encounter for fracture
M80021D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with routine healing
M80021G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with delayed healing
M80021K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with nonunion
M80021P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with malunion
M80021S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right humerus, sequela
M80022A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, initial encounter for fracture
M80022D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with routine healing
M80022G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with delayed healing
M80022K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with nonunion
M80022P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with malunion
M80022S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left humerus, sequela
M80029A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, initial encounter for 
fracture
M80029D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with routine healing

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M80029G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with delayed healing
M80029K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with nonunion
M80029P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with malunion
M80029S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified humerus, sequela
M80031A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, initial encounter for fracture
M80031D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with routine healing
M80031G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with delayed healing
M80031K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with nonunion
M80031P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with malunion
M80031S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right forearm, sequela
M80032A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, initial encounter for fracture
M80032D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with routine healing
M80032G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with delayed healing
M80032K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with nonunion

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M80032P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with malunion
M80032S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left forearm, sequela
M80039A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified forearm, initial encounter for 
fracture
M80039D
ICD-10 
Dx
Age-related osteoporosis with current pathological
fracture, unspecified forearm, subsequent encounter 
for fracture with routine healing
M80039G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with delayed healing
M80039K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with nonunion
M80039P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with malunion
M80039S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified forearm, sequela
M80041A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, initial encounter for fracture
M80041D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with routine healing
M80041G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with delayed healing
M80041K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with nonunion
M80041P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with malunion
M80041S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right hand, sequela

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M80042A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, initial encounter for fracture
M80042D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with routine healing
M80042G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with delayed healing
M80042K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with nonunion
M80042P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with malunion
M80042S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left hand, sequela
M80049A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, initial encounter for 
fracture
M80049D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with routine healing
M80049G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with delayed healing
M80049K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with nonunion
M80049P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with malunion
M80049S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified hand, sequela
M80051A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, initial encounter for fracture
M80051D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with routine healing

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Stiolto vs Trelegy V1.0 04 May
2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80051G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with delayed healing
M80051K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with nonunion
M80051P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with malunion
M80051S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right femur, sequela
M80052A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, initial encounter for fracture
M80052D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with routine healing
M80052G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with delayed healing
M80052K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with nonunion
M80052P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with malunion
M80052S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left femur, sequela
M80059A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, initial encounter for
fracture
M80059D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with routine healing
M80059G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with delayed healing
M80059K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with nonunion

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80059P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with malunion
M80059S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified femur, sequela
M80061A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, initial encounter for 
fracture
M80061D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with routine healing
M80061G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with delayed healing
M80061K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with nonunion
M80061P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with malunion
M80061S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right lower leg, sequela
M80062A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, initial encounter for fracture
M80062D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with routine healing
M80062G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with delayed healing
M80062K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with nonunion
M80062P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with malunion
M80062S
ICD-10
Dx
Age-related osteoporosis with current pathological 
fracture, left lower leg, sequela

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Stiolto vs Trelegy V1.0 04 May
2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80069A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, initial encounter for 
fracture
M80069D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with routine healing
M80069G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with delayed healing
M80069K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with nonunion
M80069P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with malunion
M80069S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified lower leg, sequela
M80071A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, initial encounter for 
fracture
M80071D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with routine healing
M80071G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with delayed healing
M80071K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with nonunion
M80071P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with malunion
M80071S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, right ankle and foot, sequela
M80072A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, initial encounter for 
fracture

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Stiolto vs Trelegy V1.0 04 May
2021
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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80072D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with routine healing
M80072G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with delayed healing
M80072K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with nonunion
M80072P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with malunion
M80072S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, left ankle and foot, sequela
M80079A
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, initial 
encounter for fracture
M80079D
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with routine healing
M80079G
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with delayed healing
M80079K
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with nonunion
M80079P
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with malunion
M80079S
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, unspecified ankle and foot, sequela
M8008XA
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), initial encounter for fracture
M8008XD
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with routine healing
M8008XG
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with delayed healing

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M8008XK
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with nonunion
M8008XP
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with malunion
M8008XS
ICD-10 
Dx
Age-related osteoporosis with current pathological 
fracture, vertebra(e), sequela
M8080XA
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, initial encounter for 
fracture
M8080XD
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with routine healing
M8080XG
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with delayed healing
M8080XK
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with nonunion
M8080XP
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, subsequent encounter for 
fracture with malunion
M8080XS
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified site, sequela
M80811A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, initial encounter for fracture
M80811D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with routine healing
M80811G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with delayed healing
M80811K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with nonunion
M80811P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, subsequent encounter for 
fracture with malunion

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80811S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right shoulder, sequela
M80812A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, initial encounter for fracture
M80812D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with routine healing
M80812G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with delayed healing
M80812K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with nonunion
M80812P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, subsequent encounter for 
fracture with malunion
M80812S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left shoulder, sequela
M80819A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, initial encounter for 
fracture
M80819D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with routine healing
M80819G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with delayed healing
M80819K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with nonunion
M80819P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, subsequent encounter 
for fracture with malunion
M80819S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified shoulder, sequela
M80821A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, initial encounter for fracture

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80821D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with routine healing
M80821G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with delayed healing
M80821K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with nonunion
M80821P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, subsequent encounter for 
fracture with malunion
M80821S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right humerus, sequela
M80822A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, initial encounter for fracture
M80822D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with routine healing
M80822G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with delayed healing
M80822K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with nonunion
M80822P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, subsequent encounter for 
fracture with malunion
M80822S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left humerus, sequela
M80829A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, initial encounter for 
fracture
M80829D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with routine healing
M80829G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with delayed healing

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80829K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with nonunion
M80829P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, subsequent encounter 
for fracture with malunion
M80829S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified humerus, sequela
M80831A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, initial encounter for fracture
M80831D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with routine healing
M80831G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with delayed healing
M80831K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with nonunion
M80831P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, subsequent encounter for 
fracture with malunion
M80831S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right forearm, sequela
M80832A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, initial encounter for fracture
M80832D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with routine healing
M80832G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with delayed healing
M80832K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with nonunion
M80832P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, subsequent encounter for 
fracture with malunion

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80832S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left forearm, sequela
M80839A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, initial encounter for 
fracture
M80839D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with routine healing
M80839G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with delayed healing
M80839K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with nonunion
M80839P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, subsequent encounter 
for fracture with malunion
M80839S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified forearm, sequela
M80841A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, initial encounter for fracture
M80841D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with routine healing
M80841G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with delayed healing
M80841K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with nonunion
M80841P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, subsequent encounter for 
fracture with malunion
M80841S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right hand, sequela
M80842A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, initial encounter for fracture

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80842D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with routine healing
M80842G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with delayed healing
M80842K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with nonunion
M80842P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, subsequent encounter for fracture 
with malunion
M80842S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left hand, sequela
M80849A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, initial encounter for 
fracture
M80849D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with routine healing
M80849G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with delayed healing
M80849K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with nonunion
M80849P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, subsequent encounter for 
fracture with malunion
M80849S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified hand, sequela
M80851A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, initial encounter for fracture
M80851D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with routine healing
M80851G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with delayed healing

BOEHRINGER INGELHEIM Group of Companies
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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80851K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with nonunion
M80851P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, subsequent encounter for 
fracture with malunion
M80851S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right femur, sequela
M80852A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, initial encounter for fracture
M80852D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with routine healing
M80852G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with delayed healing
M80852K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with nonunion
M80852P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, subsequent encounter for 
fracture with malunion
M80852S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left femur, sequela
M80859A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, initial encounter for 
fracture
M80859D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with routine healing
M80859G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with delayed healing
M80859K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with nonunion
M80859P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, subsequent encounter 
for fracture with malunion

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Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
M80859S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified femur, sequela
M80861A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, initial encounter for 
fracture
M80861D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with routine healing
M80861G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with delayed healing
M80861K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with nonunion
M80861P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, subsequent encounter for 
fracture with malunion
M80861S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right lower leg, sequela
M80862A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, initial encounter for fracture
M80862D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with routine healing
M80862G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with delayed healing
M80862K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with nonunion
M80862P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, subsequent encounter for 
fracture with malunion
M80862S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left lower leg, sequela
M80869A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, initial encounter for 
fracture

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M80869D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with routine healing
M80869G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with delayed healing
M80869K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with nonunion
M80869P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, subsequent 
encounter for fracture with malunion
M80869S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified lower leg, sequela
M80871A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, initial encounter for 
fracture
M80871D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with routine healing
M80871G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with delayed healing
M80871K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with nonunion
M80871P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, subsequent encounter 
for fracture with malunion
M80871S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, right ankle and foot, sequela
M80872A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, initial encounter for 
fracture
M80872D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with routine healing

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M80872G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with delayed healing
M80872K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with nonunion
M80872P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, subsequent encounter 
for fracture with malunion
M80872S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, left ankle and foot, sequela
M80879A
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, initial 
encounter for fracture
M80879D
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with routine healing
M80879G
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with delayed healing
M80879K
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with nonunion
M80879P
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, subsequent 
encounter for fracture with malunion
M80879S
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, unspecified ankle and foot, sequela
M8088XA
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), initial encounter for fracture
M8088XD
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with routine healing
M8088XG
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with delayed healing
M8088XK
ICD-10
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with nonunion

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M8088XP
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), subsequent encounter for 
fracture with malunion
M8088XS
ICD-10 
Dx
Other osteoporosis with current pathological 
fracture, vertebra(e), sequela
M81
ICD-10 
Dx
Osteoporosis without current pathological fracture 
M810
ICD-10 
Dx
Age-related osteoporosis without current 
pathological fracture
M816
ICD-10 
Dx
Localized osteoporosis [Lequesne]
M818
ICD-10 
Dx
Other osteoporosis without current pathological 
fracture
Z87310
ICD-10 
Dx
Personal history of (healed) osteoporosis fracture
Pulmonar
y fibrosis
515
ICD-9 
Dx
Postinflammatory pulmonary fibrosis 
500
ICD-9 
Dx
Coal workers' pneumoconiosis
501
ICD-9 
Dx
Asbestosis
502
ICD-9 
Dx
Pneumoconiosis due to other silica or silicates
503
ICD-9 
Dx
Pneumoconiosis due to other inorganic dust
504
ICD-9 
Dx
Pneumonopathy due to inhalation of other dust
505
ICD-9 
Dx
Unspecified pneumoconiosis
516.31
ICD-9 
Dx
Idiopathic pulmonary fibrosis
J60
ICD-10 
Dx
Coalworker's pneumoconiosis
J61
ICD-10 
Dx
Pneumoconiosis due to asbestos and other mineral 
fibers
J620
ICD-10 
Dx
Pneumoconiosis due to talc dust

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J628
ICD-10 
Dx
Pneumoconiosis due to other dust containing silica
J631
ICD-10 
Dx
Bauxite fibrosis (of lung)
J633
ICD-10 
Dx
Graphite fibrosis (of lung)
J636
ICD-10 
Dx
Pneumoconiosis due to other specified inorganic 
dusts
J64
ICD-10 
Dx
Unspecified pneumoconiosis
J65
ICD-10 
Dx
Pneumoconiosis associated with tuberculosis
J8410
ICD-10 
Dx
Pulmonary fibrosis, unspecified 
J84112
ICD-10 
Dx
Idiopathic pulmonary fibrosis
J8417
ICD-10 
Dx
Other interstitial pulmonary diseases with fibrosis in 
diseases classified elsewhere 
Peripheral 
vascular 
disease
250.70
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, not stated as uncontrolled
250.71
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
I [juvenile type], not stated as uncontrolled
250.72
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
II or unspecified type, uncontrolled
250.73
ICD-9 
Dx
Diabetes with peripheral circulatory disorders, type 
I [juvenile type], uncontrolled
362.30
ICD-9 
Dx
Unspecified retinal vascular occlusion
362.31
ICD-9 
Dx
Central artery occlusion of retina
362.32
ICD-9 
Dx
Arterial branch occlusion of retina
362.33
ICD-9 
Dx
Partial arterial occlusion of retina
405.01
ICD-9 
Dx
Secondary renovascular hypertension

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405.11
ICD-9 
Dx
Secondary renovascular hypertension, benign
405.19
ICD-9 
Dx
Other secondary hypertension, benign
405.91
ICD-9 
Dx
Secondary renovascular hypertension, unspecified
440.0
ICD-9 
Dx
Atherosclerosis of aorta
440.1
ICD-9 
Dx
Atherosclerosis of renal artery
440.20
ICD-9 
Dx
Atherosclerosis of native arteries of the extremities, 
unspecified
440.21
ICD-9 
Dx
Atherosclerosis of native arteries of the extremities 
with intermittent claudication
440.22
ICD-9 
Dx
Atherosclerosis of native arteries of the extremities 
with rest pain
440.23
ICD-9 
Dx
Atherosclerosis of native arteries of the extremities 
with ulceration
440.24
ICD-9 
Dx
Atherosclerosis of native arteries of the extremities 
with gangrene
440.29
ICD-9 
Dx
Other atherosclerosis of native arteries of the 
extremities
440.30
ICD-9 
Dx
Atherosclerosis of unspecified bypass graft of 
extremities
440.31
ICD-9 
Dx
Atherosclerosis of autologous vein bypass graft of 
extremities
440.32
ICD-9 
Dx
Atherosclerosis of nonautologous biological bypass 
graft of extremities
440.4
ICD-9 
Dx
Chronic total occlusion of artery of the extremities
440.8
ICD-9 
Dx
Atherosclerosis of other specified arteries
440.9
ICD-9 
Dx
Generalized and unspecified atherosclerosis
441.00
ICD-9 
Dx
Dissecting aortic aneurysm (any part), unspecified 
site

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441.01
ICD-9 
Dx
Dissecting aortic aneurysm (any part), thoracic
441.02
ICD-9 
Dx
Dissecting aortic aneurysm (any part), abdominal
441.03
ICD-9 
Dx
Dissecting aortic aneurysm (any part), 
thoracoabdominal
441.1
ICD-9 
Dx
Thoracic aneurysm, ruptured
441.2
ICD-9 
Dx
Thoracic aneurysm without mention of rupture
441.3
ICD-9 
Dx
Abdominal aneurysm, ruptured
441.4
ICD-9 
Dx
Abdominal aneurysm without mention of rupture
441.5
ICD-9 
Dx
Aortic aneurysm of unspecified site, ruptured
441.6
ICD-9 
Dx
Thoracoabdominal aneurysm, ruptured
441.7
ICD-9 
Dx
Thoracoabdominal aneurysm without mention of 
rupture
441.9
ICD-9 
Dx
Aortic aneurysm of unspecified site without 
mention of rupture
442.0
ICD-9 
Dx
Aneurysm of artery of upper extremity
442.1
ICD-9 
Dx
Aneurysm of renal artery
442.2
ICD-9 
Dx
Aneurysm of iliac artery
442.3
ICD-9 
Dx
Aneurysm of artery of lower extremity
442.81
ICD-9 
Dx
Aneurysm of artery of neck
442.82
ICD-9 
Dx
Aneurysm of subclavian artery
442.83
ICD-9 
Dx
Aneurysm of splenic artery

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442.84
ICD-9 
Dx
Aneurysm of other visceral artery
442.89
ICD-9 
Dx
Aneurysm of other specified artery
442.9
ICD-9 
Dx
Other aneurysm of unspecified site
443.0
ICD-9 
Dx
Raynaud's syndrome
443.1
ICD-9 
Dx
Thromboangiitis obliterans (Buerger's disease)
443.21
ICD-9 
Dx
Dissection of carotid artery
443.22
ICD-9 
Dx
Dissection of iliac artery
443.23
ICD-9 
Dx
Dissection of renal artery
443.24
ICD-9 
Dx
Dissection of vertebral artery
443.29
ICD-9 
Dx
Dissection of other artery
443.81
ICD-9 
Dx
Peripheral angiopathy in diseases classified 
elsewhere
443.82
ICD-9 
Dx
Erythromelalgia
443.89
ICD-9 
Dx
Other peripheral vascular disease
443.9
ICD-9 
Dx
Peripheral vascular disease, unspecified 
444.01
ICD-9 
Dx
Saddle embolus of abdominal aorta
444.09
ICD-9 
Dx
Other arterial embolism and thrombosis of 
abdominal aorta
444.1
ICD-9 
Dx
Embolism and thrombosis of thoracic aorta
444.21
ICD-9 
Dx
Embolism and thrombosis of arteries of upper 
extremity

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444.22
ICD-9 
Dx
Embolism and thrombosis of arteries of lower 
extremity
444.81
ICD-9 
Dx
Embolism and thrombosis of iliac artery
444.89
ICD-9 
Dx
Embolism and thrombosis of other specified artery
444.9
ICD-9 
Dx
Embolism and thrombosis of unspecified artery
445.01
ICD-9 
Dx
Atheroembolism of upper extremity
445.02
ICD-9 
Dx
Atheroembolism of lower extremity
445.81
ICD-9 
Dx
Atheroembolism of kidney
445.89
ICD-9 
Dx
Atheroembolism of other site
446.0
ICD-9 
Dx
Polyarteritis nodosa
446.1
ICD-9 
Dx
Acute febrile mucocutaneous lymph node syndrome 
(MCLS)
446.20
ICD-9 
Dx
Unspecified hypersensitivity angiitis
446.21
ICD-9 
Dx
Goodpasture's syndrome
446.29
ICD-9 
Dx
Other specified hypersensitivity angiitis
446.3
ICD-9 
Dx
Lethal midline granuloma
446.4
ICD-9 
Dx
Wegener's granulomatosis
446.5
ICD-9 
Dx
Giant cell arteritis
446.6
ICD-9 
Dx
Thrombotic microangiopathy
446.7
ICD-9 
Dx
Takayasu's disease

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447.0
ICD-9 
Dx
Arteriovenous fistula, acquired
447.1
ICD-9 
Dx
Stricture of artery
447.2
ICD-9 
Dx
Rupture of artery
447.3
ICD-9 
Dx
Hyperplasia of renal artery
447.4
ICD-9 
Dx
Celiac artery compression syndrome
447.5
ICD-9 
Dx
Necrosis of artery
447.6
ICD-9 
Dx
Unspecified arteritis
447.70
ICD-9 
Dx
Aortic ectasia, unspecified site
447.71
ICD-9 
Dx
Thoracic aortic ectasia
447.72
ICD-9 
Dx
Abdominal aortic ectasia
447.73
ICD-9 
Dx
Thoracoabdominal aortic ectasia
447.8
ICD-9 
Dx
Other specified disorders of arteries and arterioles
447.9
ICD-9 
Dx
Unspecified disorders of arteries and arterioles
557.1
ICD-9 
Dx
Chronic vascular insufficiency of intestine
557.9
ICD-9 
Dx
Unspecified vascular insufficiency of intestine
E0851
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic peripheral angiopathy without gangrene
E0852
ICD-10 
Dx
Diabetes mellitus due to underlying condition with 
diabetic peripheral angiopathy with gangrene
E0951
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic peripheral angiopathy without gangrene

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E0952
ICD-10 
Dx
Drug or chemical induced diabetes mellitus with 
diabetic peripheral angiopathy with gangrene
E1051
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic peripheral 
angiopathy without gangrene
E1052
ICD-10 
Dx
Type 1 diabetes mellitus with diabetic peripheral 
angiopathy with gangrene
E1151
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy without gangrene
E1152
ICD-10 
Dx
Type 2 diabetes mellitus with diabetic peripheral 
angiopathy with gangrene
E1351
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
peripheral angiopathy without gangrene
E1352
ICD-10 
Dx
Other specified diabetes mellitus with diabetic 
peripheral angiopathy with gangrene
I700
ICD-10 
Dx
Atherosclerosis of aorta
I701
ICD-10 
Dx
Atherosclerosis of renal artery
I70201
ICD-10 
Dx
Unspecified atherosclerosis of native arteries of 
extremities, right leg
I70202
ICD-10 
Dx
Unspecified atherosclerosis of native arteries of 
extremities, left leg
I70203
ICD-10 
Dx
Unspecified atherosclerosis of native arteries of 
extremities, bilateral legs
I70208
ICD-10 
Dx
Unspecified atherosclerosis of native arteries of 
extremities, other extremity
I70209
ICD-10 
Dx
Unspecified atherosclerosis of native arteries of 
extremities, unspecified extremity
I70211
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
intermittent claudication, right leg
I70212
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
intermittent claudication, left leg
I70213
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
intermittent claudication, bilateral legs
I70218
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
intermittent claudication, other extremity

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I70219
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
intermittent claudication, unspecified extremity
I70221
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
rest pain, right leg
I70222
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
rest pain, left leg
I70223
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
rest pain, bilateral legs
I70228
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
rest pain, other extremity
I70229
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
rest pain, unspecified extremity
I70231
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of thigh
I70232
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of calf
I70233
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of ankle
I70234
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of heel and midfoot
I70235
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of other part of foot
I70238
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of other part of lower right leg
I70239
ICD-10 
Dx
Atherosclerosis of native arteries of right leg with 
ulceration of unspecified site
I70241
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of thigh
I70242
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of calf
I70243
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of ankle
I70244
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of heel and midfoot
I70245
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of other part of foot

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I70248
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of other part of lower left leg
I70249
ICD-10 
Dx
Atherosclerosis of native arteries of left leg with 
ulceration of unspecified site
I7025
ICD-10 
Dx
Atherosclerosis of native arteries of other 
extremities with ulceration
I70261
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
gangrene, right leg
I70262
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
gangrene, left leg
I70263
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
gangrene, bilateral legs
I70268
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
gangrene, other extremity
I70269
ICD-10 
Dx
Atherosclerosis of native arteries of extremities with 
gangrene, unspecified extremity
I70291
ICD-10 
Dx
Other atherosclerosis of native arteries of 
extremities, right leg
I70292
ICD-10 
Dx
Other atherosclerosis of native arteries of 
extremities, left leg
I70293
ICD-10 
Dx
Other atherosclerosis of native arteries of 
extremities, bilateral legs
I70298
ICD-10 
Dx
Other atherosclerosis of native arteries of 
extremities, other extremity
I70299
ICD-10 
Dx
Other atherosclerosis of native arteries of 
extremities, unspecified extremity
I70301
ICD-10 
Dx
Unspecified atherosclerosis of unspecified type of 
bypass graft(s) of the extremities, right leg
I70302
ICD-10 
Dx
Unspecified atherosclerosis of unspecified type of 
bypass graft(s) of the extremities, left leg
I70303
ICD-10 
Dx
Unspecified atherosclerosis of unspecified type of 
bypass graft(s) of the extremities, bilateral legs
I70308
ICD-10 
Dx
Unspecified atherosclerosis of unspecified type of 
bypass graft(s) of the extremities, other extremity
I70309
ICD-10 
Dx
Unspecified atherosclerosis of unspecified type of 
bypass graft(s) of the extremities, unspecified 
extremity

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I70311
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with intermittent 
claudication, right leg
I70312
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with intermittent 
claudication, left leg
I70313
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with intermittent 
claudication, bilateral legs
I70318
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with intermittent 
claudication, other extremity
I70319
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with intermittent 
claudication, unspecified extremity
I70321
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with rest pain, right leg
I70322
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with rest pain, left leg
I70323
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with rest pain, bilateral 
legs
I70328
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with rest pain, other 
extremity
I70329
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with rest pain, unspecified 
extremity
I70331
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of thigh
I70332
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of calf
I70333
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of ankle
I70334
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of heel and 
midfoot

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70335
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of other part 
of foot
I70338
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of other part 
of lower leg
I70339
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the right leg with ulceration of 
unspecified site
I70341
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of thigh
I70342
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of calf
I70343
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of ankle
I70344
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of heel and 
midfoot
I70345
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of other part 
of foot
I70348
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of other part 
of lower leg
I70349
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the left leg with ulceration of unspecified 
site
I7035
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of other extremity with ulceration
I70361
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with gangrene, right leg
I70362
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with gangrene, left leg
I70363
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with gangrene, bilateral 
legs
I70368
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with gangrene, other 
extremity

BOEHRINGER INGELHEIM Group of Companies
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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70369
ICD-10 
Dx
Atherosclerosis of unspecified type of bypass 
graft(s) of the extremities with gangrene, 
unspecified extremity
I70391
ICD-10 
Dx
Other atherosclerosis of unspecified type of bypass 
graft(s) of the extremities, right leg
I70392
ICD-10 
Dx
Other atherosclerosis of unspecified type of bypass 
graft(s) of the extremities, left leg
I70393
ICD-10 
Dx
Other atherosclerosis of unspecified type of bypass 
graft(s) of the extremities, bilateral legs
I70398
ICD-10 
Dx
Other atherosclerosis of unspecified type of bypass 
graft(s) of the extremities, other extremity
I70399
ICD-10 
Dx
Other atherosclerosis of unspecified type of bypass 
graft(s) of the extremities, unspecified extremity
I70401
ICD-10 
Dx
Unspecified atherosclerosis of autologous vein 
bypass graft(s) of the extremities, right leg
I70402
ICD-10 
Dx
Unspecified atherosclerosis of autologous vein 
bypass graft(s) of the extremities, left leg
I70403
ICD-10 
Dx
Unspecified atherosclerosis of autologous vein 
bypass graft(s) of the extremities, bilateral legs
I70408
ICD-10 
Dx
Unspecified atherosclerosis of autologous vein 
bypass graft(s) of the extremities, other extremity
I70409
ICD-10 
Dx
Unspecified atherosclerosis of autologous vein 
bypass graft(s) of the extremities, unspecified 
extremity
I70411
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with intermittent claudication, 
right leg
I70412
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with intermittent claudication, left 
leg
I70413
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with intermittent claudication, 
bilateral legs
I70418
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with intermittent claudication, 
other extremity

BOEHRINGER INGELHEIM Group of Companies
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Page 190 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70419
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with intermittent claudication, 
unspecified extremity
I70421
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with rest pain, right leg
I70422
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with rest pain, left leg
I70423
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with rest pain, bilateral legs
I70428
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s)
of the extremities with rest pain, other extremity
I70429
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with rest pain, unspecified 
extremity
I70431
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of thigh
I70432
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of calf
I70433
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of ankle
I70434
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of heel and midfoot
I70435
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of other part of foot
I70438
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of other part of lower 
leg
I70439
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the right leg with ulceration of unspecified site
I70441
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of thigh
I70442
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of calf
I70443
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of ankle
I70444
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of heel and midfoot

BOEHRINGER INGELHEIM Group of Companies
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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70445
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of other part of foot
I70448
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of other part of lower 
leg
I70449
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the left leg with ulceration of unspecified site
I7045
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of other extremity with ulceration
I70461
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with gangrene, right leg
I70462
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with gangrene, left leg
I70463
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with gangrene, bilateral legs
I70468
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with gangrene, other extremity
I70469
ICD-10 
Dx
Atherosclerosis of autologous vein bypass graft(s) 
of the extremities with gangrene, unspecified 
extremity
I70491
ICD-10 
Dx
Other atherosclerosis of autologous vein bypass 
graft(s) of the extremities, right leg
I70492
ICD-10 
Dx
Other atherosclerosis of autologous vein bypass 
graft(s) of the extremities, left leg
I70493
ICD-10 
Dx
Other atherosclerosis of autologous vein bypass 
graft(s) of the extremities, bilateral legs
I70498
ICD-10 
Dx
Other atherosclerosis of autologous vein bypass 
graft(s) of the extremities, other extremity
I70499
ICD-10 
Dx
Other atherosclerosis of autologous vein bypass 
graft(s) of the extremities, unspecified extremity
I70501
ICD-10 
Dx
Unspecified atherosclerosis of nonautologous 
biological bypass graft(s) of the extremities, right 
leg
I70502
ICD-10 
Dx
Unspecified atherosclerosis of nonautologous 
biological bypass graft(s) of the extremities, left leg
I70503
ICD-10 
Dx
Unspecified atherosclerosis of nonautologous 
biological bypass graft(s) of the extremities, 
bilateral legs

BOEHRINGER INGELHEIM Group of Companies
c37262534-01
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Page 192 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70508
ICD-10 
Dx
Unspecified atherosclerosis of nonautologous 
biological bypass graft(s) of the extremities, other 
extremity
I70509
ICD-10 
Dx
Unspecified atherosclerosis of nonautologous 
biological bypass graft(s) of the extremities, 
unspecified extremity
I70511
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with intermittent 
claudication, right leg
I70512
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with intermittent 
claudication, left leg
I70513
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with intermittent 
claudication, bilateral legs
I70518
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with intermittent 
claudication, other extremity
I70519
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with intermittent 
claudication, unspecified extremity
I70521
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with rest pain, right leg
I70522
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with rest pain, left leg
I70523
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with rest pain, bilateral 
legs
I70528
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with rest pain, other 
extremity
I70529
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with rest pain, unspecified 
extremity
I70531
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of thigh
I70532
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of calf

BOEHRINGER INGELHEIM Group of Companies
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NIS Protocol
Page 193 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70533
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of ankle
I70534
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of heel and 
midfoot
I70535
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of other part 
of foot
I70538
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of other part 
of lower leg
I70539
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the right leg with ulceration of 
unspecified site
I70541
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of thigh
I70542
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of calf
I70543
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of ankle
I70544
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of heel and 
midfoot
I70545
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of other part 
of foot
I70548
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of other part 
of lower leg
I70549
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the left leg with ulceration of unspecified 
site
I7055
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of other extremity with ulceration
I70561
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with gangrene, right leg
I70562
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with gangrene, left leg

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Page 194 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70563
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with gangrene, bilateral 
legs
I70568
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with gangrene, other 
extremity
I70569
ICD-10 
Dx
Atherosclerosis of nonautologous biological bypass 
graft(s) of the extremities with gangrene, 
unspecified extremity
I70591
ICD-10 
Dx
Other atherosclerosis of nonautologous biological 
bypass graft(s) of the extremities, right leg
I70592
ICD-10 
Dx
Other atherosclerosis of nonautologous biological 
bypass graft(s) of the extremities, left leg
I70593
ICD-10 
Dx
Other atherosclerosis of nonautologous biological 
bypass graft(s) of the extremities, bilateral legs
I70598
ICD-10 
Dx
Other atherosclerosis of nonautologous biological 
bypass graft(s) of the extremities, other extremity
I70599
ICD-10 
Dx
Other atherosclerosis of nonautologous biological 
bypass graft(s) of the extremities, unspecified 
extremity
I70601
ICD-10 
Dx
Unspecified atherosclerosis of nonbiological bypass 
graft(s) of the extremities, right leg
I70602
ICD-10 
Dx
Unspecified atherosclerosis of nonbiological bypass 
graft(s) of the extremities, left leg
I70603
ICD-10 
Dx
Unspecified atherosclerosis of nonbiological bypass 
graft(s) of the extremities, bilateral legs
I70608
ICD-10 
Dx
Unspecified atherosclerosis of nonbiological bypass 
graft(s) of the extremities, other extremity
I70609
ICD-10 
Dx
Unspecified atherosclerosis of nonbiological bypass 
graft(s) of the extremities, unspecified extremity
I70611
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with intermittent claudication, right
leg
I70612
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with intermittent claudication, left 
leg

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70613
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with intermittent claudication, 
bilateral legs
I70618
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with intermittent claudication, other 
extremity
I70619
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with intermittent claudication, 
unspecified extremity
I70621
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with rest pain, right leg
I70622
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with rest pain, left leg
I70623
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with rest pain, bilateral legs
I70628
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with rest pain, other extremity
I70629
ICD-10
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with rest pain, unspecified extremity
I70631
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of thigh
I70632
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of calf
I70633
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of ankle
I70634
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of heel and midfoot
I70635
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of other part of foot
I70638
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of other part of lower 
leg
I70639
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the right leg with ulceration of unspecified site
I70641
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of thigh
I70642
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of calf

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70643
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of ankle
I70644
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of heel and midfoot
I70645
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of other part of foot
I70648
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of other part of lower leg
I70649
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the left leg with ulceration of unspecified site
I7065
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
other extremity with ulceration
I70661
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with gangrene, right leg
I70662
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of
the extremities with gangrene, left leg
I70663
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with gangrene, bilateral legs
I70668
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with gangrene, other extremity
I70669
ICD-10 
Dx
Atherosclerosis of nonbiological bypass graft(s) of 
the extremities with gangrene, unspecified extremity
I70691
ICD-10 
Dx
Other atherosclerosis of nonbiological bypass 
graft(s) of the extremities, right leg
I70692
ICD-10 
Dx
Other atherosclerosis of nonbiological bypass 
graft(s) of the extremities, left leg
I70693
ICD-10 
Dx
Other atherosclerosis of nonbiological bypass 
graft(s) of the extremities, bilateral legs
I70698
ICD-10 
Dx
Other atherosclerosis of nonbiological bypass 
graft(s) of the extremities, other extremity
I70699
ICD-10 
Dx
Other atherosclerosis of nonbiological bypass 
graft(s) of the extremities, unspecified extremity
I70701
ICD-10 
Dx
Unspecified atherosclerosis of other type of bypass 
graft(s) of the extremities, right leg
I70702
ICD-10 
Dx
Unspecified atherosclerosis of other type of bypass 
graft(s) of the extremities, left leg

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70703
ICD-10 
Dx
Unspecified atherosclerosis of other type of bypass 
graft(s) of the extremities, bilateral legs
I70708
ICD-10 
Dx
Unspecified atherosclerosis of other type of bypass 
graft(s) of the extremities, other extremity
I70709
ICD-10 
Dx
Unspecified atherosclerosis of other type of bypass 
graft(s) of the extremities, unspecified extremity
I70711
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with intermittent claudication, right 
leg
I70712
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with intermittent claudication, left 
leg
I70713
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with intermittent claudication, 
bilateral legs
I70718
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with intermittent claudication, other 
extremity
I70719
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with intermittent claudication, 
unspecified extremity
I70721
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with rest pain, right leg
I70722
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with rest pain, left leg
I70723
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with rest pain, bilateral legs
I70728
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with rest pain, other extremity
I70729
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with rest pain, unspecified extremity
I70731
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of thigh
I70732
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of calf
I70733
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of ankle

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Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I70734
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of heel and midfoot
I70735
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of other part of foot
I70738
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of other part of lower 
leg
I70739
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the right leg with ulceration of unspecified site
I70741
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of thigh
I70742
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of calf
I70743
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of ankle
I70744
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of heel and midfoot
I70745
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of other part of foot
I70748
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of other part of lower leg
I70749
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the left leg with ulceration of unspecified site
I7075
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
other extremity with ulceration
I70761
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with gangrene, right leg
I70762
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with gangrene, left leg
I70763
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with gangrene, bilateral legs
I70768
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with gangrene, other extremity
I70769
ICD-10 
Dx
Atherosclerosis of other type of bypass graft(s) of 
the extremities with gangrene, unspecified extremity
I70791
ICD-10 
Dx
Other atherosclerosis of other type of bypass 
graft(s) of the extremities, right leg

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I70792
ICD-10 
Dx
Other atherosclerosis of other type of bypass 
graft(s) of the extremities, left leg
I70793
ICD-10 
Dx
Other atherosclerosis of other type of bypass 
graft(s) of the extremities, bilateral legs
I70798
ICD-10 
Dx
Other atherosclerosis of other type of bypass 
graft(s) of the extremities, other extremity
I70799
ICD-10 
Dx
Other atherosclerosis of other type of bypass 
graft(s) of the extremities, unspecified extremity
I708
ICD-10 
Dx
Atherosclerosis of other arteries
I7090
ICD-10 
Dx
Unspecified atherosclerosis
I7091
ICD-10 
Dx
Generalized atherosclerosis
I7092
ICD-10 
Dx
Chronic total occlusion of artery of the extremities
I7100
ICD-10 
Dx
Dissection of unspecified site of aorta
I7101
ICD-10 
Dx
Dissection of thoracic aorta
I7102
ICD-10 
Dx
Dissection of abdominal aorta
I7103
ICD-10 
Dx
Dissection of thoracoabdominal aorta
I711
ICD-10 
Dx
Thoracic aortic aneurysm, ruptured
I712
ICD-10 
Dx
Thoracic aortic aneurysm, without rupture
I713
ICD-10 
Dx
Abdominal aortic aneurysm, ruptured
I714
ICD-10 
Dx
Abdominal aortic aneurysm, without rupture
I715
ICD-10 
Dx
Thoracoabdominal aortic aneurysm, ruptured
I716
ICD-10 
Dx
Thoracoabdominal aortic aneurysm, without rupture

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I718
ICD-10 
Dx
Aortic aneurysm of unspecified site, ruptured
I719
ICD-10 
Dx
Aortic aneurysm of unspecified site, without rupture
I720
ICD-10 
Dx
Aneurysm of carotid artery
I721
ICD-10 
Dx
Aneurysm of artery of upper extremity
I722
ICD-10 
Dx
Aneurysm of renal artery
I723
ICD-10 
Dx
Aneurysm of iliac artery
I724
ICD-10 
Dx
Aneurysm of artery of lower extremity
I728
ICD-10 
Dx
Aneurysm of other specified arteries
I729
ICD-10 
Dx
Aneurysm of unspecified site
I7300
ICD-10 
Dx
Raynaud's syndrome without gangrene
I7301
ICD-10 
Dx
Raynaud's syndrome with gangrene
I731
ICD-10 
Dx
Thromboangiitis obliterans [Buerger's disease]
I7381
ICD-10 
Dx
Erythromelalgia
I7389
ICD-10 
Dx
Other specified peripheral vascular diseases
I739
ICD-10 
Dx
Peripheral vascular disease, unspecified 
I739
ICD-10 
Dx
Peripheral vascular disease, unspecified
I7401
ICD-10 
Dx
Saddle embolus of abdominal aorta
I7409
ICD-10 
Dx
Other arterial embolism and thrombosis of 
abdominal aorta

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I7410
ICD-10 
Dx
Embolism and thrombosis of unspecified parts of 
aorta
I7411
ICD-10 
Dx
Embolism and thrombosis of thoracic aorta
I7419
ICD-10 
Dx
Embolism and thrombosis of other parts of aorta
I742
ICD-10 
Dx
Embolism and thrombosis of arteries of the upper 
extremities
I743
ICD-10 
Dx
Embolism and thrombosis of arteries of the lower 
extremities
I744
ICD-10 
Dx
Embolism and thrombosis of arteries of extremities, 
unspecified
I745
ICD-10 
Dx
Embolism and thrombosis of iliac artery
I748
ICD-10 
Dx
Embolism and thrombosis of other arteries
I749
ICD-10 
Dx
Embolism and thrombosis of unspecified artery
I75011
ICD-10 
Dx
Atheroembolism of right upper extremity
I75012
ICD-10 
Dx
Atheroembolism of left upper extremity
I75013
ICD-10 
Dx
Atheroembolism of bilateral upper extremities
I75019
ICD-10 
Dx
Atheroembolism of unspecified upper extremity
I75021
ICD-10 
Dx
Atheroembolism of right lower extremity
I75022
ICD-10 
Dx
Atheroembolism of left lower extremity
I75023
ICD-10 
Dx
Atheroembolism of bilateral lower extremities
I75029
ICD-10 
Dx
Atheroembolism of unspecified lower extremity
I7581
ICD-10 
Dx
Atheroembolism of kidney

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I7589
ICD-10 
Dx
Atheroembolism of other site
I76
ICD-10 
Dx
Septic arterial embolism
I770
ICD-10
Dx
Arteriovenous fistula, acquired
I771
ICD-10 
Dx
Stricture of artery
I772
ICD-10 
Dx
Rupture of artery
I773
ICD-10 
Dx
Arterial fibromuscular dysplasia
I774
ICD-10 
Dx
Celiac artery compression syndrome
I775
ICD-10 
Dx
Necrosis of artery
I776
ICD-10 
Dx
Arteritis, unspecified
I7771
ICD-10 
Dx
Dissection of carotid artery
I7772
ICD-10 
Dx
Dissection of iliac artery
I7773
ICD-10 
Dx
Dissection of renal artery
I7774
ICD-10 
Dx
Dissection of vertebral artery
I7779
ICD-10 
Dx
Dissection of other artery
I77810
ICD-10 
Dx
Thoracic aortic ectasia
I77811
ICD-10 
Dx
Abdominal aortic ectasia
I77812
ICD-10 
Dx
Thoracoabdominal aortic ectasia
I77819
ICD-10 
Dx
Aortic ectasia, unspecified site

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I7789
ICD-10 
Dx
Other specified disorders of arteries and arterioles
I779
ICD-10 
Dx
Disorder of arteries and arterioles, unspecified
I780
ICD-10 
Dx
Hereditary hemorrhagic telangiectasia
I781
ICD-10 
Dx
Nevus, non-neoplastic
I788
ICD-10 
Dx
Other diseases of capillaries
I789
ICD-10 
Dx
Disease of capillaries, unspecified
I790
ICD-10 
Dx
Aneurysm of aorta in diseases classified elsewhere
I791
ICD-10 
Dx
Aortitis in diseases classified elsewhere
I798
ICD-10 
Dx
Other disorders of arteries, arterioles and capillaries 
in diseases classified elsewhere
K551
ICD-10 
Dx
Chronic vascular disorders of intestine
Z95820
ICD-10 
Dx
Peripheral vascular angioplasty status with implants 
and grafts
Spirometr
y
94010
CPT
Spirometry, including graphic record, total and 
timed vital capacity, expiratory flow rate 
measurement(s), with or without maximal voluntary 
ventilation
94014
CPT
Patient-initiated spirometric recording per 30-day 
period of time; includes reinforced education, 
transmission of spirometric tracing, data capture, 
analysis of transmitted data, periodic recalibration 
and review and interpretation by a physician or 
other qualified health care professional
94015
CPT
Patient-initiated spirometric recording per 30-day 
period of time; recording (includes hook-up, 
reinforced education, data transmission, data 
capture, trend analysis, and periodic recalibration)
94016
CPT
Patient-initiated spirometric recording per 30-day 
period of time; review and interpretation only by a 
physician or other qualified health care professional

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94060
CPT
Bronchodilation responsiveness, spirometry as in 
94010, pre- and post-bronchodilator administration
94070
CPT
Bronchospasm provocation evaluation, multiple 
spirometric determinations as in 94010, with 
administered agents (eg, antigen[s], cold air, 
methacholine)
94150
CPT
Vital capacity, total (separate procedure)
94200
CPT
Maximum breathing capacity, maximal voluntary 
ventilation
4A0971Z
ICD-10 
Proc
Measurement of Respiratory Capacity, Via Natural 
or Artificial Opening
4A0975Z
ICD-10 
Proc
Measurement of Respiratory Flow, Via Natural or 
Artificial Opening
4A097LZ
ICD-10 
Proc
Measurement of Respiratory Volume, Via Natural 
or Artificial Opening
4A0981Z
ICD-10 
Proc
Measurement of Respiratory Capacity, Via Natural 
or Artificial Opening Endoscopic
4A0985Z
ICD-10 
Proc
Measurement of Respiratory Flow, Via Natural or 
Artificial Opening Endoscopic
4A098LZ
ICD-10 
Proc
Measurement of Respiratory Volume, Via Natural 
or Artificial Opening Endoscopic
4A09X1Z
ICD-10 
Proc
Measurement of Respiratory Capacity, External 
Approach
4A09X5Z
ICD-10 
Proc
Measurement of Respiratory Flow, External 
Approach
4A09XLZ
ICD-10 
Proc
Measurement of Respiratory Volume, External 
Approach
89.37
ICD-9 
Proc
Vital capacity determination
94375
CPT
Respiratory flow volume loop
94400
CPT
Breathing response to CO2 (CO2 response curve)
94450
CPT
Breathing response to hypoxia (hypoxia response 
curve)
94620
CPT
Pulmonary stress testing; simple (e.g., six-minute 
walk test, prolonged exercise test for bronchospasm 
with pre- and post-spirometry and oximetry)

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4A097DZ
ICD-10 
Proc
Measurement of Respiratory Resistance, Via 
Natural or Artificial Opening
4A097MZ
ICD-10 
Proc
Measurement of Respiratory Total Activity, Via 
Natural or Artificial Opening
4A098DZ
ICD-10 
Proc
Measurement of Respiratory Resistance, Via 
Natural or Artificial Opening Endoscopic
4A098MZ
ICD-10 
Proc
Measurement of Respiratory Total Activity, Via 
Natural or Artificial Opening Endoscopic
4A09XDZ
ICD-10 
Proc
Measurement of Respiratory Resistance, External 
Approach
4A09XMZ
ICD-10 
Proc
Measurement of Respiratory Total Activity, 
External Approach
89.38
ICD-9 
Proc
Other nonoperative respiratory measurements
Peptic 
ulcer/GER
D
530.11
ICD-9 
Dx
Reflux esophagitis 
530.81
ICD-9 
Dx
Esophageal reflux 
533
ICD-9 
Dx
Peptic ulcer, site unspecified 
533.00
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with 
hemorrhage, without mention of obstruction
533.01
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with 
hemorrhage and obstruction
533.10
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with 
perforation, without mention of obstruction
533.11
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with perforation 
and obstruction
533.20
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with 
hemorrhage and perforation, without mention of 
obstruction
533.21
ICD-9 
Dx
Acute peptic ulcer, unspecified site, with 
hemorrhage, perforation, and obstruction
533.30
ICD-9 
Dx
Acute peptic ulcer, unspecified site, without 
mention of hemorrhage, perforation, or obstruction

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533.31
ICD-9 
Dx
Acute peptic ulcer, unspecified site, without 
mention of hemorrhage and perforation, with 
obstruction
533.40
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with hemorrhage, without mention of 
obstruction
533.41
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with hemorrhage and obstruction
533.50
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with perforation, without mention of 
obstruction
533.51
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with perforation and obstruction
533.60
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with hemorrhage and perforation, without 
mention of obstruction
533.61
ICD-9 
Dx
Chronic or unspecified peptic ulcer, unspecified 
site, with hemorrhage, perforation, and obstruction
533.70
ICD-9 
Dx
Chronic peptic ulcer, unspecified site, without 
mention of hemorrhage, perforation, or obstruction
533.71
ICD-9 
Dx
Chronic peptic ulcer of unspecified site without 
mention of hemorrhage or perforation, with 
obstruction
533.90
ICD-9 
Dx
Peptic ulcer, unspecified site, unspecified as acute 
or chronic, without mention of hemorrhage, 
perforation, or obstruction
533.91
ICD-9 
Dx
Peptic ulcer, unspecified site, unspecified as acute 
or chronic, without mention of hemorrhage or 
perforation, with obstruction
K210
ICD-10 
Dx
Gastro-esophageal reflux disease with esophagitis
K219
ICD-10 
Dx
Gastro-esophageal reflux disease without 
esophagitis
K27
ICD-10 
Dx
Peptic ulcer, site unspecified 
K270
ICD-10 
Dx
Acute peptic ulcer, site unspecified, with 
hemorrhage

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K271
ICD-10 
Dx
Acute peptic ulcer, site unspecified, with perforation
K272
ICD-10 
Dx
Acute peptic ulcer, site unspecified, with both 
hemorrhage and perforation
K273
ICD-10 
Dx
Acute peptic ulcer, site unspecified, without 
hemorrhage or perforation
K274
ICD-10 
Dx
Chronic or unspecified peptic ulcer, site 
unspecified, with hemorrhage
K275
ICD-10 
Dx
Chronic or unspecified peptic ulcer, site 
unspecified, with perforation
K276
ICD-10 
Dx
Chronic or unspecified peptic ulcer, site 
unspecified, with both hemorrhage and perforation
K277
ICD-10 
Dx
Chronic peptic ulcer, site unspecified, without 
hemorrhage or perforation
K279
ICD-10 
Dx
Peptic ulcer, site unspecified, unspecified as acute 
or chronic, without hemorrhage or perforation
Renal 
disease
792.5
ICD-9 
Dx
Cloudy (hemodialysis) (peritoneal) dialysis affluent
996.56
ICD-9 
Dx
Mechanical complications due to peritoneal dialysis 
catheter
996.68
ICD-9 
Dx
Infection or inflammation due to peritoneal dialysis 
catheter
996.73
ICD-9 
Dx
Other complications due to renal dialysis device, 
implant, and graft
996.81
ICD-9 
Dx
Complications of transplanted kidney
249.40
ICD-9 
Dx
Secondary diabetes mellitus with renal 
manifestations
249.41
ICD-9 
Dx
Secondary diabetes mellitus with renal 
manifestations, uncontrolled
250.40
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, not stated as uncontrolled
250.41
ICD-9 
Dx
Diabetes with renal manifestations, type I [juvenile 
type], not stated as uncontrolled
250.42
ICD-9 
Dx
Diabetes with renal manifestations, type II or 
unspecified type, uncontrolled

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250.43
ICD-9 
Dx
Diabetes with renal manifestations, type I [juvenile 
type], uncontrolled
285.21
ICD-9 
Dx
Anemia in chronic kidney disease
403.00
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.01
ICD-9 
Dx
Hypertensive chronic kidney disease, malignant, 
with chronic kidney disease stage V or end stage 
renal disease
403.10
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage I through stage IV, or 
unspecified
403.11
ICD-9 
Dx
Hypertensive chronic kidney disease, benign, with 
chronic kidney disease stage V or end stage renal 
disease
403.90
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage I through stage 
IV, or unspecified
403.91
ICD-9 
Dx
Hypertensive chronic kidney disease, unspecified, 
with chronic kidney disease stage V or end stage 
renal disease
404.00
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.01
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.02
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.03
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
malignant, with heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.10
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified

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404.11
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and with chronic kidney 
disease stage I through stage IV, or unspecified
404.12
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.13
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
benign, with heart failure and chronic kidney 
disease stage V or end stage renal disease
404.90
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.91
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and with chronic 
kidney disease stage I through stage IV, or 
unspecified
404.92
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, without heart failure and with chronic 
kidney disease stage V or end stage renal disease
404.93
ICD-9 
Dx
Hypertensive heart and chronic kidney disease, 
unspecified, with heart failure and chronic kidney 
disease stage V or end stage renal disease
405.01
ICD-9 
Dx
Secondary renovascular hypertension, malignant
405.11
ICD-9 
Dx
Secondary renovascular hypertension, benign
405.91
ICD-9 
Dx
Secondary renovascular hypertension, unspecified
458.21
ICD-9 
Dx
Hypotension of hemodialysis
580.0
ICD-9 
Dx
Acute glomerulonephritis with lesion of 
proliferative glomerulonephritis
580.4
ICD-9 
Dx
Acute glomerulonephritis with lesion of rapidly 
progressive glomerulonephritis
580.81
ICD-9 
Dx
Acute glomerulonephritis with other specified 
pathological lesion in kidney in disease classified 
elsewhere

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580.89
ICD-9 
Dx
Other acute glomerulonephritis with other specified 
pathological lesion in kidney
580.9
ICD-9 
Dx
Acute glomerulonephritis with unspecified 
pathological lesion in kidney
581.0
ICD-9 
Dx
Nephrotic syndrome with lesion of proliferative 
glomerulonephritis
581.1
ICD-9 
Dx
Nephrotic syndrome with lesion of membranous 
glomerulonephritis
581.2
ICD-9 
Dx
Nephrotic syndrome with lesion of 
membranoproliferative glomerulonephritis
581.3
ICD-9 
Dx
Nephrotic syndrome with lesion of minimal change 
glomerulonephritis
581.81
ICD-9 
Dx
Nephrotic syndrome with other specified 
pathological lesion in kidney in diseases classified 
elsewhere
581.89
ICD-9 
Dx
Other nephrotic syndrome with specified 
pathological lesion in kidney
581.9
ICD-9 
Dx
Nephrotic syndrome with unspecified pathological 
lesion in kidney
582.0
ICD-9 
Dx
Chronic glomerulonephritis with lesion of 
proliferative glomerulonephritis
582.1
ICD-9 
Dx
Chronic glomerulonephritis with lesion of 
membranous glomerulonephritis
582.2
ICD-9 
Dx
Chronic glomerulonephritis with lesion of 
membranoproliferative glomerulonephritis
582.4
ICD-9 
Dx
Chronic glomerulonephritis with lesion of rapidly 
progressive glomerulonephritis
582.81
ICD-9 
Dx
Chronic glomerulonephritis with other specified 
pathological lesion in kidney in diseases classified 
elsewhere
582.89
ICD-9 
Dx
Other chronic glomerulonephritis with specified 
pathological lesion in kidney
582.9
ICD-9 
Dx
Chronic glomerulonephritis with unspecified 
pathological lesion in kidney
583.0
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of proliferative 
glomerulonephritis

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583.1
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of membranous 
glomerulonephritis
583.2
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of membranoproliferative 
glomerulonephritis
583.4
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of rapidly progressive 
glomerulonephritis
583.6
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of renal cortical necrosis
583.7
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with lesion of renal medullary necrosis
583.81
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with other specified pathological lesion in 
kidney, in diseases classified elsewhere
583.89
ICD-9 
Dx
Other nephritis and nephropathy, not specified as 
acute or chronic, with specified pathological lesion 
in kidney
583.9
ICD-9 
Dx
Nephritis and nephropathy, not specified as acute or 
chronic, with unspecified pathological lesion in 
kidney
584.5
ICD-9 
Dx
Acute kidney failure with lesion of tubular necrosis
584.6
ICD-9 
Dx
Acute kidney failure with lesion of renal  cortical 
necrosis
584.7
ICD-9 
Dx
Acute kidney failure with lesion of medullary 
[papillary] necrosis
584.8
ICD-9 
Dx
Acute kidney failure with other specified 
pathological lesion in kidney
584.9
ICD-9 
Dx
Acute kidney failure, unspecified
585.1
ICD-9 
Dx
Chronic kidney disease, Stage I
585.2
ICD-9 
Dx
Chronic kidney disease, Stage II (mild)
585.3
ICD-9 
Dx
Chronic kidney disease, Stage III (moderate)

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585.4
ICD-9 
Dx
Chronic kidney disease, Stage IV (severe)
585.5
ICD-9 
Dx
Chronic kidney disease, Stage V
585.6
ICD-9 
Dx
End stage renal disease
585.9
ICD-9 
Dx
Chronic kidney disease, unspecified
586
ICD-9 
Dx
Unspecified renal failure
587
ICD-9 
Dx
Unspecified renal sclerosis
588.0
ICD-9 
Dx
Renal osteodystrophy
588.1
ICD-9 
Dx
Nephrogenic diabetes insipidus
588.81
ICD-9 
Dx
Secondary hyperparathyroidism (of renal origin)
588.89
ICD-9 
Dx
Other specified disorders resulting from impaired 
renal function
588.9
ICD-9 
Dx
Unspecified disorder resulting from impaired renal 
function
589.0
ICD-9 
Dx
Unilateral small kidney
589.1
ICD-9 
Dx
Bilateral small kidneys
589.9
ICD-9 
Dx
Unspecified small kidney
590.00
ICD-9 
Dx
Chronic pyelonephritis without lesion of renal 
medullary necrosis
590.01
ICD-9 
Dx
Chronic pyelonephritis with lesion of renal 
medullary necrosis
590.10
ICD-9 
Dx
Acute pyelonephritis without lesion of renal 
medullary necrosis
590.11
ICD-9 
Dx
Acute pyelonephritis with lesion of renal medullary 
necrosis

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590.2
ICD-9 
Dx
Renal and perinephric abscess
590.3
ICD-9 
Dx
Pyeloureteritis cystica
590.80
ICD-9 
Dx
Unspecified pyelonephritis
590.81
ICD-9 
Dx
Pyelitis or pyelonephritis in diseases classified 
elsewhere
590.9
ICD-9 
Dx
Unspecified infection of kidney
591
ICD-9 
Dx
Hydronephrosis
592.0
ICD-9 
Dx
Calculus of kidney
592.1
ICD-9 
Dx
Calculus of ureter
592.9
ICD-9 
Dx
Unspecified urinary calculus
593.0
ICD-9 
Dx
Nephroptosis
593.1
ICD-9 
Dx
Hypertrophy of kidney
593.2
ICD-9 
Dx
Acquired cyst of kidney
593.6
ICD-9 
Dx
Postural proteinuria
593.70
ICD-9 
Dx
Vesicoureteral reflux, unspecified or without reflex 
nephropathy
593.71
ICD-9 
Dx
Vesicoureteral reflux with reflux nephropathy, 
unilateral
593.72
ICD-9 
Dx
Vesicoureteral reflux with reflux nephropathy, 
bilateral
593.73
ICD-9 
Dx
Vesicoureteral reflux with reflux nephropathy, NOS
593.81
ICD-9 
Dx
Vascular disorders of kidney

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593.89
ICD-9 
Dx
Other specified disorder of kidney and ureter
593.9
ICD-9 
Dx
Unspecified disorder of kidney and ureter
599.60
ICD-9 
Dx
Urinary obstruction, unspecified
599.69
ICD-9 
Dx
Urinary obstruction, not elsewhere classified
599.70
ICD-9 
Dx
Hematuria, unspecified
599.71
ICD-9 
Dx
Gross hematuria
599.72
ICD-9 
Dx
Microscopic hematuria
E879.1
ICD-9 
Dx
Kidney dialysis as the cause of abnormal reaction of 
patient, or of later complication, without mention of 
misadventure at time of procedure
V42.0
ICD-9 
Dx
Kidney replaced by transplant
V45.11
ICD-9 
Dx
Renal dialysis status
V45.12
ICD-9 
Dx
Noncompliance with renal dialysis
V56.0
ICD-9 
Dx
Encounter for extracorporeal dialysis
V56.1
ICD-9 
Dx
Fitting and adjustment of extracorporeal dialysis 
catheter
V56.2
ICD-9 
Dx
Fitting and adjustment of peritoneal dialysis catheter
V56.31
ICD-9 
Dx
Encounter for adequacy testing for hemodialysis
V56.32
ICD-9 
Dx
Encounter for adequacy testing for peritoneal 
dialysis
V56.8
ICD-9 
Dx
Encounter other dialysis
N000
ICD-10 
Dx
Acute nephritic syndrome with minor glomerular 
abnormality

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N001
ICD-10 
Dx
Acute nephritic syndrome with focal and segmental 
glomerular lesions
N002
ICD-10 
Dx
Acute nephritic syndrome with diffuse membranous 
glomerulonephritis
N003
ICD-10 
Dx
Acute nephritic syndrome with diffuse mesangial 
proliferative glomerulonephritis
N004
ICD-10 
Dx
Acute nephritic syndrome with diffuse 
endocapillary proliferative glomerulonephritis
N005
ICD-10 
Dx
Acute nephritic syndrome with diffuse 
mesangiocapillary glomerulonephritis
N006
ICD-10 
Dx
Acute nephritic syndrome with dense deposit 
disease
N007
ICD-10 
Dx
Acute nephritic syndrome with diffuse crescentic 
glomerulonephritis
N008
ICD-10 
Dx
Acute nephritic syndrome with other morphologic 
changes
N009
ICD-10 
Dx
Acute nephritic syndrome with unspecified 
morphologic changes
N010
ICD-10 
Dx
Rapidly progressive nephritic syndrome with minor 
glomerular abnormality
N011
ICD-10 
Dx
Rapidly progressive nephritic syndrome with focal 
and segmental glomerular lesions
N012
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
diffuse membranous glomerulonephritis
N013
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
diffuse mesangial proliferative glomerulonephritis
N014
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
diffuse endocapillary proliferative 
glomerulonephritis
N015
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
diffuse mesangiocapillary glomerulonephritis
N016
ICD-10 
Dx
Rapidly progressive nephritic syndrome with dense 
deposit disease
N017
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
diffuse crescentic glomerulonephritis
N018
ICD-10 
Dx
Rapidly progressive nephritic syndrome with other 
morphologic changes

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N019
ICD-10 
Dx
Rapidly progressive nephritic syndrome with 
unspecified morphologic changes
N020
ICD-10 
Dx
Recurrent and persistent hematuria with minor 
glomerular abnormality
N021
ICD-10 
Dx
Recurrent and persistent hematuria with focal and 
segmental glomerular lesions
N022
ICD-10 
Dx
Recurrent and persistent hematuria with diffuse 
membranous glomerulonephritis
N023
ICD-10 
Dx
Recurrent and persistent hematuria with diffuse 
mesangial proliferative glomerulonephritis
N024
ICD-10 
Dx
Recurrent and persistent hematuria with diffuse 
endocapillary proliferative glomerulonephritis
N025
ICD-10 
Dx
Recurrent and persistent hematuria with diffuse 
mesangiocapillary glomerulonephritis
N026
ICD-10 
Dx
Recurrent and persistent hematuria with dense 
deposit disease
N027
ICD-10 
Dx
Recurrent and persistent hematuria with diffuse 
crescentic glomerulonephritis
N028
ICD-10 
Dx
Recurrent and persistent hematuria with other 
morphologic changes
N029
ICD-10 
Dx
Recurrent and persistent hematuria with unspecified 
morphologic changes
N030
ICD-10 
Dx
Chronic nephritic syndrome with minor glomerular 
abnormality
N031
ICD-10 
Dx
Chronic nephritic syndrome with focal and 
segmental glomerular lesions
N032
ICD-10 
Dx
Chronic nephritic syndrome with diffuse 
membranous glomerulonephritis
N033
ICD-10 
Dx
Chronic nephritic syndrome with diffuse mesangial 
proliferative glomerulonephritis
N034
ICD-10 
Dx
Chronic nephritic syndrome with diffuse 
endocapillary proliferative glomerulonephritis
N035
ICD-10 
Dx
Chronic nephritic syndrome with diffuse 
mesangiocapillary glomerulonephritis
N036
ICD-10 
Dx
Chronic nephritic syndrome with dense deposit 
disease

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N037
ICD-10 
Dx
Chronic nephritic syndrome with diffuse crescentic 
glomerulonephritis
N038
ICD-10 
Dx
Chronic nephritic syndrome with other morphologic 
changes
N039
ICD-10 
Dx
Chronic nephritic syndrome with unspecified 
morphologic changes
N040
ICD-10 
Dx
Nephrotic syndrome with minor glomerular 
abnormality
N041
ICD-10 
Dx
Nephrotic syndrome with focal and segmental 
glomerular lesions
N042
ICD-10 
Dx
Nephrotic syndrome with diffuse membranous 
glomerulonephritis
N043
ICD-10 
Dx
Nephrotic syndrome with diffuse mesangial 
proliferative glomerulonephritis
N044
ICD-10 
Dx
Nephrotic syndrome with diffuse endocapillary 
proliferative glomerulonephritis
N045
ICD-10 
Dx
Nephrotic syndrome with diffuse mesangiocapillary 
glomerulonephritis
N046
ICD-10 
Dx
Nephrotic syndrome with dense deposit disease
N047
ICD-10 
Dx
Nephrotic syndrome with diffuse crescentic 
glomerulonephritis
N048
ICD-10 
Dx
Nephrotic syndrome with other morphologic 
changes
N049
ICD-10 
Dx
Nephrotic syndrome with unspecified morphologic 
changes
N050
ICD-10 
Dx
Unspecified nephritic syndrome with minor 
glomerular abnormality
N051
ICD-10 
Dx
Unspecified nephritic syndrome with focal and 
segmental glomerular lesions
N052
ICD-10 
Dx
Unspecified nephritic syndrome with diffuse 
membranous glomerulonephritis
N053
ICD-10 
Dx
Unspecified nephritic syndrome with diffuse 
mesangial proliferative glomerulonephritis
N054
ICD-10 
Dx
Unspecified nephritic syndrome with diffuse 
endocapillary proliferative glomerulonephritis

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N055
ICD-10 
Dx
Unspecified nephritic syndrome with diffuse 
mesangiocapillary glomerulonephritis
N056
ICD-10 
Dx
Unspecified nephritic syndrome with dense deposit 
disease
N057
ICD-10 
Dx
Unspecified nephritic syndrome with diffuse 
crescentic glomerulonephritis
N058
ICD-10 
Dx
Unspecified nephritic syndrome with other 
morphologic changes
N059
ICD-10 
Dx
Unspecified nephritic syndrome with unspecified 
morphologic changes
N060
ICD-10 
Dx
Isolated proteinuria with minor glomerular 
abnormality
N061
ICD-10 
Dx
Isolated proteinuria with focal and segmental 
glomerular lesions
N062
ICD-10 
Dx
Isolated proteinuria with diffuse membranous 
glomerulonephritis
N063
ICD-10 
Dx
Isolated proteinuria with diffuse mesangial 
proliferative glomerulonephritis
N064
ICD-10 
Dx
Isolated proteinuria with diffuse endocapillary 
proliferative glomerulonephritis
N065
ICD-10 
Dx
Isolated proteinuria with diffuse mesangiocapillary 
glomerulonephritis
N066
ICD-10 
Dx
Isolated proteinuria with dense deposit disease
N067
ICD-10 
Dx
Isolated proteinuria with diffuse crescentic 
glomerulonephritis
N068
ICD-10 
Dx
Isolated proteinuria with other morphologic lesion
N069
ICD-10 
Dx
Isolated proteinuria with unspecified morphologic 
lesion
N070
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with minor glomerular abnormality
N071
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with focal and segmental glomerular lesions
N072
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with diffuse membranous glomerulonephritis

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N073
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with diffuse mesangial proliferative 
glomerulonephritis
N074
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with diffuse endocapillary proliferative 
glomerulonephritis
N075
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with diffuse mesangiocapillary glomerulonephritis
N076
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with dense deposit disease
N077
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with diffuse crescentic glomerulonephritis
N078
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with other morphologic lesions
N079
ICD-10 
Dx
Hereditary nephropathy, not elsewhere classified 
with unspecified morphologic lesions
N08
ICD-10 
Dx
Glomerular disorders in diseases classified 
elsewhere
N10
ICD-10 
Dx
Acute pyelonephritis
N110
ICD-10 
Dx
Nonobstructive reflux-associated chronic 
pyelonephritis
N111
ICD-10 
Dx
Chronic obstructive pyelonephritis
N118
ICD-10 
Dx
Other chronic tubulo-interstitial nephritis
N119
ICD-10 
Dx
Chronic tubulo-interstitial nephritis, unspecified
N12
ICD-10 
Dx
Tubulo-interstitial nephritis, not specified as acute 
or chronic
N131
ICD-10 
Dx
Hydronephrosis with ureteral stricture, not 
elsewhere classified
N132
ICD-10 
Dx
Hydronephrosis with renal and ureteral calculous 
obstruction
N1330
ICD-10 
Dx
Unspecified hydronephrosis

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N1339
ICD-10 
Dx
Other hydronephrosis
N134
ICD-10 
Dx
Hydroureter
N135
ICD-10 
Dx
Crossing vessel and stricture of ureter without 
hydronephrosis
N136
ICD-10 
Dx
Pyonephrosis
N1370
ICD-10 
Dx
Vesicoureteral-reflux, unspecified
N1371
ICD-10 
Dx
Vesicoureteral-reflux without reflux nephropathy
N13721
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy 
without hydroureter, unilateral
N13722
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy 
without hydroureter, bilateral
N13729
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy 
without hydroureter, unspecified
N13731
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy with 
hydroureter, unilateral
N13732
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy with 
hydroureter, bilateral
N13739
ICD-10 
Dx
Vesicoureteral-reflux with reflux nephropathy with 
hydroureter, unspecified
N138
ICD-10 
Dx
Other obstructive and reflux uropathy
N139
ICD-10 
Dx
Obstructive and reflux uropathy, unspecified
N140
ICD-10 
Dx
Analgesic nephropathy
N141
ICD-10 
Dx
Nephropathy induced by other drugs, medicaments 
and biological substances
N142
ICD-10 
Dx
Nephropathy induced by unspecified drug, 
medicament or biological substance
N143
ICD-10 
Dx
Nephropathy induced by heavy metals

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N144
ICD-10 
Dx
Toxic nephropathy, not elsewhere classified
N150
ICD-10 
Dx
Balkan nephropathy
N151
ICD-10 
Dx
Renal and perinephric abscess
N158
ICD-10 
Dx
Other specified renal tubulo-interstitial diseases
N159
ICD-10 
Dx
Renal tubulo-interstitial disease, unspecified
N16
ICD-10 
Dx
Renal tubulo-interstitial disorders in diseases 
classified elsewhere
N170
ICD-10 
Dx
Acute kidney failure with tubular necrosis
N171
ICD-10 
Dx
Acute kidney failure with acute cortical necrosis
N172
ICD-10 
Dx
Acute kidney failure with medullary necrosis
N178
ICD-10 
Dx
Other acute kidney failure
N179
ICD-10 
Dx
Acute kidney failure, unspecified
N181
ICD-10 
Dx
Chronic kidney disease, stage 1
N182
ICD-10 
Dx
Chronic kidney disease, stage 2 (mild)
N183
ICD-10 
Dx
Chronic kidney disease, stage 3 (moderate)
N184
ICD-10 
Dx
Chronic kidney disease, stage 4 (severe)
N185
ICD-10 
Dx
Chronic kidney disease, stage 5
N186
ICD-10 
Dx
End stage renal disease
N189
ICD-10 
Dx
Chronic kidney disease, unspecified

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N19
ICD-10 
Dx
Unspecified kidney failure
N200
ICD-10 
Dx
Calculus of kidney
N201
ICD-10 
Dx
Calculus of ureter
N202
ICD-10 
Dx
Calculus of kidney with calculus of ureter
N209
ICD-10 
Dx
Urinary calculus, unspecified
N210
ICD-10 
Dx
Calculus in bladder
N211
ICD-10 
Dx
Calculus in urethra
N218
ICD-10 
Dx
Other lower urinary tract calculus
N219
ICD-10 
Dx
Calculus of lower urinary tract, unspecified
N22
ICD-10 
Dx
Calculus of urinary tract in diseases classified 
elsewhere
N23
ICD-10 
Dx
Unspecified renal colic
N250
ICD-10 
Dx
Renal osteodystrophy
N251
ICD-10 
Dx
Nephrogenic diabetes insipidus
N2581
ICD-10 
Dx
Secondary hyperparathyroidism of renal origin
N2589
ICD-10 
Dx
Other disorders resulting from impaired renal 
tubular function
N259
ICD-10 
Dx
Disorder resulting from impaired renal tubular 
function, unspecified
N261
ICD-10 
Dx
Atrophy of kidney (terminal)
N262
ICD-10 
Dx
Page kidney

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N269
ICD-10 
Dx
Renal sclerosis, unspecified
N270
ICD-10 
Dx
Small kidney, unilateral
N271
ICD-10 
Dx
Small kidney, bilateral
N279
ICD-10 
Dx
Small kidney, unspecified
N280
ICD-10 
Dx
Ischemia and infarction of kidney
N281
ICD-10 
Dx
Cyst of kidney, acquired
N2881
ICD-10 
Dx
Hypertrophy of kidney
N2884
ICD-10
Dx
Pyelitis cystica
N2885
ICD-10 
Dx
Pyeloureteritis cystica
N2889
ICD-10 
Dx
Other specified disorders of kidney and ureter
N289
ICD-10 
Dx
Disorder of kidney and ureter, unspecified
R802
ICD-10 
Dx
Orthostatic proteinuria, unspecified
Sleep 
apnea
327.23
ICD-9 
Dx
Obstructive sleep apnea (adult) (pediatric)
780.51
ICD-9 
Dx
Insomnia with sleep apnea, unspecified
780.53
ICD-9 
Dx
Hypersomnia with sleep apnea, unspecified
780.57
ICD-9 
Dx
Unspecified sleep apnea
327.20
ICD-9 
Dx
Organic sleep apnea, unspecified 
327.21
ICD-9 
Dx
Primary central sleep apnea 

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327.22
ICD-9 
Dx
High altitude periodic breathing 
327.24
ICD-9 
Dx
Idiopathic sleep related nonobstructive alveolar 
hypoventilation 
327.25
ICD-9 
Dx
Congenital central alveolar hypoventilation 
syndrome 
327.26
ICD-9 
Dx
Sleep related hypoventilation/hypoxemia in 
conditions classifiable elsewhere 
327.27
ICD-9 
Dx
Central sleep apnea in conditions classified 
elsewhere 
327.29
ICD-9 
Dx
Other organic sleep apnea 
G473
ICD-10 
Dx
Sleep apnea
G4730
ICD-10 
Dx
Sleep apnea, unspecified 
G4731
ICD-10 
Dx
Primary central sleep apnea 
G4732
ICD-10 
Dx
High altitude periodic breathing 
G4733
ICD-10 
Dx
Obstructive sleep apnea (adult) (pediatric) 
G4734
ICD-10 
Dx
Idiopathic sleep related nonobstructive alveolar 
hypoventilation 
G4735
ICD-10 
Dx
Congenital central alveolar hypoventilation 
syndrome 
G4736
ICD-10 
Dx
Sleep related hypoventilation in conditions 
classifiable elsewhere 
G4737
ICD-10 
Dx
Central sleep apnea in conditions classified 
elsewhere 
G4739
ICD-10 
Dx
other sleep apnea
Stroke
430
ICD-9 
Dx
Subarachnoid hemorrhage
431
ICD-9 
Dx
Intracerebral hemorrhage

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432.9
ICD-9 
Dx
Unspecified intracranial hemorrhage
433.01
ICD-9 
Dx
Occlusion and stenosis of basilar artery with 
cerebral infarction
433.11
ICD-9 
Dx
Occlusion and stenosis of carotid artery with 
cerebral infarction
433.21
ICD-9 
Dx
Occlusion and stenosis of vertebral artery with 
cerebral infarction
433.31
ICD-9 
Dx
Occlusion and stenosis of multiple and bilateral 
precerebral arteries with cerebral infarction
433.81
ICD-9 
Dx
Occlusion and stenosis of other specified 
precerebral artery with cerebral infarction
433.91
ICD-9
Dx
Occlusion and stenosis of unspecified precerebral 
artery with cerebral infarction
434.01
ICD-9 
Dx
Cerebral thrombosis with cerebral infarction
434.11
ICD-9 
Dx
Cerebral embolism with cerebral infarction
434.91
ICD-9 
Dx
Unspecified cerebral artery occlusion with cerebral 
infarction
346.60
ICD-9 
Dx
Persistent migraine aura with cerebral infarction, 
without mention of intractable migraine without 
mention of status migrainosus
346.61
ICD-9 
Dx
Persistent migraine aura with cerebral infarction, 
with intractable migraine, so stated, without 
mention of status migrainosus
346.62
ICD-9 
Dx
Persistent migraine aura with cerebral infarction, 
without mention of intractable migraine with status 
migrainosus
346.63
ICD-9 
Dx
Persistent migraine aura with cerebral infarction, 
with intractable migraine, so stated, with status 
migrainosus
997.02
ICD-9 
Dx
Iatrogenic cerebrovascular infarction or hemorrhage
G43501
ICD-10 
Dx
Persistent migraine aura without cerebral infarction, 
not intractable, with status migrainosus
G43509
ICD-10 
Dx
Persistent migraine aura without cerebral infarction, 
not intractable, without status migrainosus

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G43511
ICD-10 
Dx
Persistent migraine aura without cerebral infarction, 
intractable, with status migrainosus
G43519
ICD-10 
Dx
Persistent migraine aura without cerebral infarction, 
intractable, without status migrainosus
G43601
ICD-10 
Dx
Persistent migraine aura with cerebral infarction, 
not intractable, with status migrainosus
G43609
ICD-10 
Dx
Persistent migraine aura with cerebral infarction, 
not intractable, without status migrainosus
G43611
ICD-10 
Dx
Persistent migraine aura with cerebral infarction, 
intractable, with status migrainosus
G43619
ICD-10 
Dx
Persistent migraine aura with cerebral infarction, 
intractable, without status migrainosus
G463
ICD-10 
Dx
Brain stem stroke syndrome
G464
ICD-10 
Dx
Cerebellar stroke syndrome
G465
ICD-10 
Dx
Pure motor lacunar syndrome
G466
ICD-10 
Dx
Pure sensory lacunar syndrome
G467
ICD-10 
Dx
Other lacunar syndromes
I6000
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified carotid siphon and bifurcation
I6001
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from right 
carotid siphon and bifurcation
I6002
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from left
carotid siphon and bifurcation
I6010
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified middle cerebral artery
I6011
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from right 
middle cerebral artery
I6012
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from left 
middle cerebral artery
I602
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
anterior communicating artery

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I6020
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified anterior communicating artery
I6021
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from right 
anterior communicating artery
I6022
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from left 
anterior communicating artery
I6030
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified posterior communicating artery
I6031
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from right 
posterior communicating artery
I6032
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from left 
posterior communicating artery
I604
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
basilar artery
I6050
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified vertebral artery
I6051
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from right 
vertebral artery
I6052
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from left 
vertebral artery
I606
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from other 
intracranial arteries
I607
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage from 
unspecified intracranial artery
I608
ICD-10 
Dx
Other nontraumatic subarachnoid hemorrhage
I609
ICD-10 
Dx
Nontraumatic subarachnoid hemorrhage, 
unspecified
I610
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage in 
hemisphere, subcortical
I611
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage in 
hemisphere, cortical
I612
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage in 
hemisphere, unspecified
I613
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage in brain 
stem

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I614
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage in 
cerebellum
I615
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage, 
intraventricular
I616
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage, multiple 
localized
I618
ICD-10 
Dx
Other nontraumatic intracerebral hemorrhage
I619
ICD-10 
Dx
Nontraumatic intracerebral hemorrhage, unspecified
I6200
ICD-10 
Dx
Nontraumatic subdural hemorrhage, unspecified
I6203
ICD-10 
Dx
Nontraumatic chronic subdural hemorrhage
I621
ICD-10 
Dx
Nontraumatic extradural hemorrhage
I629
ICD-10 
Dx
Nontraumatic intracranial hemorrhage, unspecified
I6300
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
precerebral artery
I63011
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
vertebral artery
I63012
ICD-10 
Dx
Cerebral infarction due to thrombosis of left 
vertebral artery
I63013
ICD-10 
Dx
Cerebral infarction due to thrombosis of bilateral 
vertebral arteries
I63019
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
vertebral artery
I6302
ICD-10 
Dx
Cerebral infarction due to thrombosis of basilar 
artery
I63031
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
carotid artery
I63032
ICD-10 
Dx
Cerebral infarction due to thrombosis of left carotid 
artery
I63033
ICD-10 
Dx
Cerebral infarction due to thrombosis of bilateral 
carotid arteries

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I63039
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
carotid artery
I6309
ICD-10 
Dx
Cerebral infarction due to thrombosis of other 
precerebral artery
I6310
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
precerebral artery
I63111
ICD-10 
Dx
Cerebral infarction due to embolism of right 
vertebral artery
I63112
ICD-10 
Dx
Cerebral infarction due to embolism of left vertebral 
artery
I63113
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
vertebral arteries
I63119
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
vertebral artery
I6312
ICD-10 
Dx
Cerebral infarction due to embolism of basilar 
artery
I63131
ICD-10 
Dx
Cerebral infarction due to embolism of right carotid 
artery
I63132
ICD-10 
Dx
Cerebral infarction due to embolism of left carotid 
artery
I63133
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
carotid arteries
I63139
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
carotid artery
I6319
ICD-10 
Dx
Cerebral infarction due to embolism of other 
precerebral artery
I6320
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified precerebral arteries
I63211
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right vertebral arteries
I63212
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left vertebral arteries
I63213
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral vertebral arteries
I63219
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified vertebral arteries

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I6322
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of basilar arteries
I63231
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right carotid arteries
I63232
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left carotid arteries
I63233
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral carotid arteries
I63239
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified carotid arteries
I6329
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of other precerebral arteries
I6330
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
cerebral artery
I63311
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
middle cerebral artery
I63312
ICD-10 
Dx
Cerebral infarction due to thrombosis of left middle 
cerebral artery
I63313
ICD-10 
Dx
Cerebral infarction due to thrombosis of bilateral 
middle cerebral arteries
I63319
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
middle cerebral artery
I63321
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
anterior cerebral artery
I63322
ICD-10 
Dx
Cerebral infarction due to thrombosis of left anterior 
cerebral artery
I63323
ICD-10 
Dx
Cerebral infarction due to thrombosis of bilateral 
anterior arteries
I63329
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
anterior cerebral artery
I63331
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
posterior cerebral artery
I63332
ICD-10 
Dx
Cerebral infarction due to thrombosis of left 
posterior cerebral artery
I63333
ICD-10 
Dx
Cerebral infarction to thrombosis of bilateral 
posterior arteries

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I63339
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
posterior cerebral artery
I63341
ICD-10 
Dx
Cerebral infarction due to thrombosis of right 
cerebellar artery
I63342
ICD-10 
Dx
Cerebral infarction due to thrombosis of left 
cerebellar artery
I63343
ICD-10 
Dx
Cerebral infarction to thrombosis of bilateral 
cerebellar arteries
I63349
ICD-10 
Dx
Cerebral infarction due to thrombosis of unspecified 
cerebellar artery
I6339
ICD-10 
Dx
Cerebral infarction due to thrombosis of other 
cerebral artery
I6340
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
cerebral artery
I63411
ICD-10 
Dx
Cerebral infarction due to embolism of right middle 
cerebral artery
I63412
ICD-10 
Dx
Cerebral infarction due to embolism of left middle 
cerebral artery
I63413
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
middle cerebral arteries
I63419
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
middle cerebral artery
I63421
ICD-10 
Dx
Cerebral infarction due to embolism of right 
anterior cerebral artery
I63422
ICD-10 
Dx
Cerebral infarction due to embolism of left anterior 
cerebral artery
I63423
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
anterior cerebral arteries
I63429
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
anterior cerebral artery
I63431
ICD-10 
Dx
Cerebral infarction due to embolism of right 
posterior cerebral artery
I63432
ICD-10 
Dx
Cerebral infarction due to embolism of left posterior 
cerebral artery
I63433
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
posterior cerebral arteries

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I63439
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
posterior cerebral artery
I63441
ICD-10 
Dx
Cerebral infarction due to embolism of right 
cerebellar artery
I63442
ICD-10 
Dx
Cerebral infarction due to embolism of left 
cerebellar artery
I63443
ICD-10 
Dx
Cerebral infarction due to embolism of bilateral 
cerebellar arteries
I63449
ICD-10 
Dx
Cerebral infarction due to embolism of unspecified 
cerebellar artery
I6349
ICD-10 
Dx
Cerebral infarction due to embolism of other 
cerebral artery
I6350
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified cerebral artery
I63511
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right middle cerebral artery
I63512
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left middle cerebral artery
I63513
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral middle arteries
I63519
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified middle cerebral artery
I63521
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right anterior cerebral artery
I63522
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left anterior cerebral artery
I63523
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral anterior arteries
I63529
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified anterior cerebral artery
I63531
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right posterior cerebral artery
I63532
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left posterior cerebral artery
I63533
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral posterior arteries

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I63539
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified posterior cerebral artery
I63541
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of right cerebellar artery
I63542
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of left cerebellar artery
I63543
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of bilateral cerebellar arteries
I63549
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of unspecified cerebellar artery
I6359
ICD-10 
Dx
Cerebral infarction due to unspecified occlusion or 
stenosis of other cerebral artery
I636
ICD-10 
Dx
Cerebral infarction due to cerebral venous 
thrombosis, nonpyogenic
I638
ICD-10 
Dx
Other cerebral infarction
I639
ICD-10 
Dx
Cerebral infarction, unspecified
I6900
ICD-10 
Dx
Unspecified sequelae of nontraumatic subarachnoid 
hemorrhage
I6901
ICD-10 
Dx
Cognitive deficits following nontraumatic 
subarachnoid hemorrhage
I69010
ICD-10 
Dx
Attention and concentration deficit following 
nontraumatic subarachnoid hemorrhage
I69011
ICD-10 
Dx
Memory deficit following nontraumatic 
subarachnoid hemorrhage
I69012
ICD-10 
Dx
Visuospatial deficit and spatial neglect following 
nontraumatic subarachnoid hemorrhage
I69013
ICD-10 
Dx
Psychomotor deficit following nontraumatic 
subarachnoid hemorrhage
I69014
ICD-10 
Dx
Frontal lobe and executive function deficit 
following nontraumatic subarachnoid hemorrhage
I69015
ICD-10 
Dx
Cognitive social or emotional deficit following 
nontraumatic subarachnoid hemorrhage
I69018
ICD-10 
Dx
Other symptoms and signs involving cognitive 
functions following nontraumatic subarachnoid 
hemorrhage

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I69019
ICD-10 
Dx
Unspecified symptoms and signs involving 
cognitive functions following nontraumatic 
subarachnoid hemorrhage
I69020
ICD-10 
Dx
Aphasia following nontraumatic subarachnoid 
hemorrhage
I69021
ICD-10 
Dx
Dysphasia following nontraumatic subarachnoid 
hemorrhage
I69022
ICD-10 
Dx
Dysarthria following nontraumatic subarachnoid 
hemorrhage
I69023
ICD-10 
Dx
Fluency disorder following nontraumatic 
subarachnoid hemorrhage
I69028
ICD-10 
Dx
Other speech and language deficits following 
nontraumatic subarachnoid hemorrhage
I69031
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
subarachnoid hemorrhage affecting right dominant 
side
I69032
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
subarachnoid hemorrhage affecting left dominant 
side
I69033
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
subarachnoid hemorrhage affecting right non-
dominant side
I69034
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
subarachnoid hemorrhage affecting left non-
dominant side
I69039
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
subarachnoid hemorrhage affecting unspecified side
I69041
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
subarachnoid hemorrhage affecting right dominant 
side
I69042
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
subarachnoid hemorrhage affecting left dominant 
side
I69043
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
subarachnoid hemorrhage affecting right non-
dominant side
I69044
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
subarachnoid hemorrhage affecting left non-
dominant side

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MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
I69049
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
subarachnoid hemorrhage affecting unspecified side
I69051
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
subarachnoid hemorrhage affecting right dominant 
side
I69052
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
subarachnoid hemorrhage affecting left dominant 
side
I69053
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
subarachnoid hemorrhage affecting right non-
dominant side
I69054
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
subarachnoid hemorrhage affecting left non-
dominant side
I69059
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
subarachnoid hemorrhage affecting unspecified side
I69061
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage affecting right dominant 
side
I69062
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage affecting left dominant 
side
I69063
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage affecting right non-
dominant side
I69064
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage affecting left non-
dominant side
I69065
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage, bilateral
I69069
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
subarachnoid hemorrhage affecting unspecified side
I69090
ICD-10 
Dx
Apraxia following nontraumatic subarachnoid 
hemorrhage
I69091
ICD-10 
Dx
Dysphagia following nontraumatic subarachnoid 
hemorrhage
I69092
ICD-10 
Dx
Facial weakness following nontraumatic 
subarachnoid hemorrhage

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I69093
ICD-10 
Dx
Ataxia following nontraumatic subarachnoid 
hemorrhage
I69098
ICD-10 
Dx
Other sequelae following nontraumatic 
subarachnoid hemorrhage
I6910
ICD-10 
Dx
Unspecified sequelae of nontraumatic intracerebral 
hemorrhage
I6911
ICD-10 
Dx
Cognitive deficits following nontraumatic 
intracerebral hemorrhage
I69110
ICD-10 
Dx
Attention and concentration deficit following 
nontraumatic intracerebral hemorrhage
I69111
ICD-10 
Dx
Memory deficit following nontraumatic 
intracerebral hemorrhage
I69112
ICD-10 
Dx
Visuospatial deficit and spatial neglect following 
nontraumatic intracerebral hemorrhage
I69113
ICD-10 
Dx
Psychomotor deficit following nontraumatic 
intracerebral hemorrhage
I69114
ICD-10 
Dx
Frontal lobe and executive function deficit 
following nontraumatic intracerebral hemorrhage
I69115
ICD-10 
Dx
Cognitive social or emotional deficit following 
nontraumatic intracerebral hemorrhage
I69118
ICD-10 
Dx
Other symptoms and signs involving cognitive 
functions following nontraumatic intracerebral 
hemorrhage
I69119
ICD-10 
Dx
Unspecified symptoms and signs involving 
cognitive functions following nontraumatic 
intracerebral hemorrhage
I69120
ICD-10 
Dx
Aphasia following nontraumatic intracerebral 
hemorrhage
I69121
ICD-10 
Dx
Dysphasia following nontraumatic intracerebral 
hemorrhage
I69122
ICD-10 
Dx
Dysarthria following nontraumatic intracerebral 
hemorrhage
I69123
ICD-10 
Dx
Fluency disorder following nontraumatic 
intracerebral hemorrhage
I69128
ICD-10 
Dx
Other speech and language deficits following 
nontraumatic intracerebral hemorrhage

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I69131
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
intracerebral hemorrhage affecting right dominant 
side
I69132
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
intracerebral hemorrhage affecting left dominant 
side
I69133
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
intracerebral hemorrhage affecting right non-
dominant side
I69134
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
intracerebral hemorrhage affecting left non-
dominant side
I69139
ICD-10 
Dx
Monoplegia of upper limb following nontraumatic 
intracerebral hemorrhage affecting unspecified side
I69141
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
intracerebral hemorrhage affecting right dominant 
side
I69142
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
intracerebral hemorrhage affecting left dominant 
side
I69143
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
intracerebral hemorrhage affecting right non-
dominant side
I69144
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
intracerebral hemorrhage affecting left non-
dominant side
I69149
ICD-10 
Dx
Monoplegia of lower limb following nontraumatic 
intracerebral hemorrhage affecting unspecified side
I69151
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
intracerebral hemorrhage affecting right dominant 
side
I69152
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
intracerebral hemorrhage affecting left dominant 
side
I69153
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
intracerebral hemorrhage affecting right non-
dominant side

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I69154
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
intracerebral hemorrhage affecting left non-
dominant side
I69159
ICD-10 
Dx
Hemiplegia and hemiparesis following nontraumatic 
intracerebral hemorrhage affecting unspecified side
I69161
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage affecting right dominant 
side
I69162
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage affecting left dominant 
side
I69163
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage affecting right non-
dominant side
I69164
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage affecting left non-
dominant side
I69165
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage, bilateral
I69169
ICD-10 
Dx
Other paralytic syndrome following nontraumatic 
intracerebral hemorrhage affecting unspecified side
I69190
ICD-10 
Dx
Apraxia following nontraumatic intracerebral 
hemorrhage
I69191
ICD-10 
Dx
Dysphagia following nontraumatic intracerebral 
hemorrhage
I69192
ICD-10 
Dx
Facial weakness following nontraumatic 
intracerebral hemorrhage
I69193
ICD-10 
Dx
Ataxia following nontraumatic intracerebral 
hemorrhage
I69198
ICD-10 
Dx
Other sequelae of nontraumatic intracerebral 
hemorrhage
I6920
ICD-10 
Dx
Unspecified sequelae of other nontraumatic 
intracranial hemorrhage
I6921
ICD-10 
Dx
Cognitive deficits following other nontraumatic 
intracranial hemorrhage
I69210
ICD-10 
Dx
Attention and concentration deficit following other 
nontraumatic intracranial hemorrhage

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I69211
ICD-10 
Dx
Memory deficit following other nontraumatic 
intracranial hemorrhage
I69212
ICD-10 
Dx
Visuospatial deficit and spatial neglect following 
other nontraumatic intracranial hemorrhage
I69213
ICD-10 
Dx
Psychomotor deficit following other nontraumatic 
intracranial hemorrhage
I69214
ICD-10 
Dx
Frontal lobe and executive function deficit 
following other nontraumatic intracranial 
hemorrhage
I69215
ICD-10 
Dx
Cognitive social or emotional deficit following 
other nontraumatic intracranial hemorrhage
I69218
ICD-10 
Dx
Other symptoms and signs involving cognitive 
functions following other nontraumatic intracranial 
hemorrhage
I69219
ICD-10 
Dx
Unspecified symptoms and signs involving 
cognitive functions following other nontraumatic 
intracranial hemorrhage
I69220
ICD-10
Dx
Aphasia following other nontraumatic intracranial 
hemorrhage
I69221
ICD-10 
Dx
Dysphasia following other nontraumatic intracranial 
hemorrhage
I69222
ICD-10 
Dx
Dysarthria following other nontraumatic intracranial 
hemorrhage
I69223
ICD-10 
Dx
Fluency disorder following other nontraumatic 
intracranial hemorrhage
I69228
ICD-10 
Dx
Other speech and language deficits following other 
nontraumatic intracranial hemorrhage
I69231
ICD-10 
Dx
Monoplegia of upper limb following other 
nontraumatic intracranial hemorrhage affecting right 
dominant side
I69232
ICD-10 
Dx
Monoplegia of upper limb following other 
nontraumatic intracranial hemorrhage affecting left 
dominant side
I69233
ICD-10 
Dx
Monoplegia of upper limb following other 
nontraumatic intracranial hemorrhage affecting right 
non-dominant side

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I69234
ICD-10 
Dx
Monoplegia of upper limb following other 
nontraumatic intracranial hemorrhage affecting left 
non-dominant side
I69239
ICD-10 
Dx
Monoplegia of upper limb following other 
nontraumatic intracranial hemorrhage affecting 
unspecified side
I69241
ICD-10 
Dx
Monoplegia of lower limb following other 
nontraumatic intracranial hemorrhage affecting right 
dominant side
I69242
ICD-10 
Dx
Monoplegia of lower limb following other 
nontraumatic intracranial hemorrhage affecting left 
dominant side
I69243
ICD-10 
Dx
Monoplegia of lower limb following other 
nontraumatic intracranial hemorrhage affecting right 
non-dominant side
I69244
ICD-10 
Dx
Monoplegia of lower limb following other 
nontraumatic intracranial hemorrhage affecting left 
non-dominant side
I69249
ICD-10 
Dx
Monoplegia of lower limb following other 
nontraumatic intracranial hemorrhage affecting 
unspecified side
I69251
ICD-10 
Dx
Hemiplegia and hemiparesis following other 
nontraumatic intracranial hemorrhage affecting right 
dominant side
I69252
ICD-10 
Dx
Hemiplegia and hemiparesis following other 
nontraumatic intracranial hemorrhage affecting left 
dominant side
I69253
ICD-10 
Dx
Hemiplegia and hemiparesis following other 
nontraumatic intracranial hemorrhage affecting right 
non-dominant side
I69254
ICD-10 
Dx
Hemiplegia and hemiparesis following other 
nontraumatic intracranial hemorrhage affecting left 
non-dominant side
I69259
ICD-10 
Dx
Hemiplegia and hemiparesis following other 
nontraumatic intracranial hemorrhage affecting 
unspecified side
I69261
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage affecting right 
dominant side

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I69262
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage affecting left 
dominant side
I69263
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage affecting right 
non-dominant side
I69264
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage affecting left 
non-dominant side
I69265
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage, bilateral
I69269
ICD-10 
Dx
Other paralytic syndrome following other 
nontraumatic intracranial hemorrhage affecting 
unspecified side
I69290
ICD-10 
Dx
Apraxia following other nontraumatic intracranial 
hemorrhage
I69291
ICD-10 
Dx
Dysphagia following other nontraumatic intracranial 
hemorrhage
I69292
ICD-10 
Dx
Facial weakness following other nontraumatic 
intracranial hemorrhage
I69293
ICD-10 
Dx
Ataxia following other nontraumatic intracranial 
hemorrhage
I69298
ICD-10 
Dx
Other sequelae of other nontraumatic intracranial 
hemorrhage
I6930
ICD-10 
Dx
Unspecified sequelae of cerebral infarction
I6931
ICD-10 
Dx
Cognitive deficits following cerebral infarction
I69310
ICD-10 
Dx
Attention and concentration deficit following 
cerebral infarction
I69311
ICD-10 
Dx
Memory deficit following cerebral infarction
I69312
ICD-10 
Dx
Visuospatial deficit and spatial neglect following 
cerebral infarction
I69313
ICD-10 
Dx
Psychomotor deficit following cerebral infarction
I69314
ICD-10 
Dx
Frontal lobe and executive function deficit 
following cerebral infarction

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I69315
ICD-10 
Dx
Cognitive social or emotional deficit following 
cerebral infarction
I69318
ICD-10 
Dx
Other symptoms and signs involving cognitive 
functions following cerebral infarction
I69319
ICD-10 
Dx
Unspecified symptoms and signs involving 
cognitive functions following cerebral infarction
I69320
ICD-10 
Dx
Aphasia following cerebral infarction
I69321
ICD-10 
Dx
Dysphasia following cerebral infarction
I69322
ICD-10 
Dx
Dysarthria following cerebral infarction
I69323
ICD-10 
Dx
Fluency disorder following cerebral infarction
I69328
ICD-10 
Dx
Other speech and language deficits following 
cerebral infarction
I69331
ICD-10 
Dx
Monoplegia of upper limb following cerebral 
infarction affecting right dominant side
I69332
ICD-10 
Dx
Monoplegia of upper limb following cerebral 
infarction affecting left dominant side
I69333
ICD-10 
Dx
Monoplegia of upper limb following cerebral 
infarction affecting right non-dominant side
I69334
ICD-10 
Dx
Monoplegia of upper limb following cerebral 
infarction affecting left non-dominant side
I69339
ICD-10 
Dx
Monoplegia of upper limb following cerebral 
infarction affecting unspecified side
I69341
ICD-10 
Dx
Monoplegia of lower limb following cerebral 
infarction affecting right dominant side
I69342
ICD-10 
Dx
Monoplegia of lower limb following cerebral 
infarction affecting left dominant side
I69343
ICD-10 
Dx
Monoplegia of lower limb following cerebral 
infarction affecting right non-dominant side
I69344
ICD-10 
Dx
Monoplegia of lower limb following cerebral 
infarction affecting left non-dominant side
I69349
ICD-10 
Dx
Monoplegia of lower limb following cerebral 
infarction affecting unspecified side

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I69351
ICD-10 
Dx
Hemiplegia and hemiparesis following cerebral 
infarction affecting right dominant side
I69352
ICD-10 
Dx
Hemiplegia and hemiparesis following cerebral 
infarction affecting left dominant side
I69353
ICD-10 
Dx
Hemiplegia and hemiparesis following cerebral 
infarction affecting right non-dominant side
I69354
ICD-10 
Dx
Hemiplegia and hemiparesis following cerebral 
infarction affecting left non-dominant side
I69359
ICD-10 
Dx
Hemiplegia and hemiparesis following cerebral 
infarction affecting unspecified side
I69361
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction affecting right dominant side
I69362
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction affecting left dominant side
I69363
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction affecting right non-dominant side
I69364
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction affecting left non-dominant side
I69365
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction, bilateral
I69369
ICD-10 
Dx
Other paralytic syndrome following cerebral 
infarction affecting unspecified side
I69390
ICD-10 
Dx
Apraxia following cerebral infarction
I69391
ICD-10 
Dx
Dysphagia following cerebral infarction
I69392
ICD-10 
Dx
Facial weakness following cerebral infarction
I69393
ICD-10 
Dx
Ataxia following cerebral infarction
I69398
ICD-10 
Dx
Other sequelae of cerebral infarction
I97810
ICD-10 
Dx
Intraoperative cerebrovascular infarction during 
cardiac surgery
I97811
ICD-10 
Dx
Intraoperative cerebrovascular infarction during 
other surgery

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I97820
ICD-10 
Dx
Postprocedural cerebrovascular infarction following 
cardiac surgery
I97821
ICD-10 
Dx
Postprocedural cerebrovascular infarction following 
other surgery
Oxygen 
use
31730
CPT
Transtracheal (percutaneous) introduction of needle 
wire dilator/stent or indwelling tube for oxygen 
therapy
E0424
HCPC
S
Stationary compressed gaseous oxygen system, 
rental; includes container, contents, regulator, 
flowmeter, humidifier, nebulizer, cannula or mask, 
and tubing
E0425
HCPC
S
Stationary compressed gas system, purchase; 
includes regulator, flowmeter, humidifier, nebulizer, 
cannula or mask, and tubing
E0430
HCPC
S
Portable gaseous oxygen system, purchase; includes 
regulator, flowmeter, humidifier, cannula or mask, 
and tubing
E0431
HCPC
S
Portable gaseous oxygen system, rental; includes 
portable container, regulator, flowmeter, humidifier, 
cannula or mask, and tubing
E0433
HCPC
S
Portable liquid oxygen system, rental; home 
liquefier used to fill portable liquid oxygen 
containers, includes portable containers, regulator, 
flowmeter, humidifier, cannula or mask and tubing, 
with or without supply reservoir and contents gauge
E0434
HCPC
S
Portable liquid oxygen system, rental; includes 
portable container, supply reservoir, humidifier, 
flowmeter, refill adaptor, contents gauge, cannula or 
mask, and tubing
E0435
HCPC
S
Portable liquid oxygen system, purchase; includes 
portable container, supply reservoir, flowmeter, 
humidifier, contents gauge, cannula or mask, tubing 
and refill adaptor
E0439
HCPC
S
Stationary liquid oxygen system, rental; includes 
container, contents, regulator, flowmeter, 
humidifier, nebulizer, cannula or mask, & tubing
E0440
HCPC
S
Stationary liquid oxygen system, purchase; includes 
use of reservoir, contents indicator, regulator, 
flowmeter, humidifier, nebulizer, cannula or mask, 
and tubing

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E0441
HCPC
S
Stationary oxygen contents, gaseous, 1 month's 
supply = 1 unit
E0442
HCPC
S
Stationary oxygen contents, liquid, 1 month's supply 
= 1 unit
E0443
HCPC
S
Portable oxygen contents, gaseous, 1 month's supply 
= 1 unit
E0444
HCPC
S
Portable oxygen contents, liquid, 1 month's supply = 
1 unit
E0445
HCPC
S
Oximeter device for measuring blood oxygen levels 
non-invasively
E1390
HCPC
S
Oxygen concentrator, single delivery port, capable 
of delivering 85 percent or greater oxygen 
concentration at the prescribed flow rate
E1391
HCPC
S
Oxygen concentrator, dual delivery port, capable of 
delivering 85 percent or greater oxygen 
concentration at the prescribed flow rate, each
E1392
HCPC
S
Portable oxygen concentrator, rental
E1405
HCPC
S
Oxygen and water vapor enriching system with 
heated delivery
E1406
HCPC
S
Oxygen and water vapor enriching system without 
heated delivery
G0277
HCPC
S
Hyperbaric oxygen under pressure, full body 
chamber, per 30 minute interval
K0738
HCPC
S
Portable gaseous oxygen system, rental; home 
compressor used to fill portable oxygen cylinders; 
includes portable containers, regulator, flowmeter, 
humidifier, cannula or mask, and tubing
K0741
HCPC
S
Portable gaseous oxygen system, rental, includes 
portable container, regulator, flowmeter, humidifier, 
cannula or mask, and tubing, for cluster headaches
K0742
HCPC
S
Portable oxygen contents, gaseous, 1 month's supply 
= 1 unit, for cluster headaches, for initial months 
supply or to replace used contents
S8120
HCPC
S
Oxygen contents, gaseous, 1 unit equals 1 cubic foot
S8121
HCPC
S
Oxygen contents, liquid, 1 unit equals 1 pound

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E0447
HCPC
S
Portable oxygen contents, liquid, 1 month's supply = 
1 unit, prescribed amount at rest or nighttime 
exceeds 4 liters per minute (lpm)
Z9981
ICD-10 
Dx
Dependence on supplemental oxygen
0277
Revenu
e Code
Medical/Surgical Supplies and Devices - Take-
home oxygen
0413
Revenu
e Code
Respiratory Services - Hyperbaric oxygen therapy
0600
Revenu
e Code
Home Health Oxygen - General
0601
Revenu
e Code
Home Health Oxygen - Stat/Equip/Supply or 
contents
0602
Revenu
e Code
Home Health Oxygen - Stat/Equip/Supply Under 1 
LPM
0603
Revenu
e Code
Home Health Oxygen - Stat/Equip Over 4 LPM
0604
Revenu
e Code
Home Health Oxygen - Portable Add-on
0609
Revenu
e Code
Home Health Oxygen - Other
4030F
CPT
Long-term oxygen therapy prescribed (more than 15 
hours per day) (COPD)
A4608
HCPC
S
Transtracheal oxygen catheter, each
E0455
HCPC
S
Oxygen tent, excluding croup or pediatric tents (?)
V46.2
ICD-9 
Dx
Supplemental oxygen
93.96
ICD-9 
Proc
Other oxygen enrichment
0544
Revenu
e Code
Oxygen
Tobacco 
use
305.1
ICD-9 
Dx
Nondependent tobacco use disorder
989.84
ICD-9 
Dx
Toxic effect of tobacco

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V15.82
ICD-9 
Dx
Personal history of tobacco use, presenting hazards 
to health
HZ80ZZZ
ICD-10 
Proc
Medication Management for Substance Abuse 
Treatment, Nicotine Replacement
HZ90ZZZ
ICD-10 
Proc
Pharmacotherapy for Substance Abuse Treatment, 
Nicotine Replacement
F17200
ICD-10 
Dx
Nicotine dependence, unspecified, uncomplicated
F17201
ICD-10 
Dx
Nicotine dependence, unspecified, in remission
F17203
ICD-10 
Dx
Nicotine dependence unspecified, with withdrawal
F17208
ICD-10 
Dx
Nicotine dependence, unspecified, with other
nicotine-induced disorders
F17209
ICD-10 
Dx
Nicotine dependence, unspecified, with unspecified 
nicotine-induced disorders
F17210
ICD-10 
Dx
Nicotine dependence, cigarettes, uncomplicated
F17211
ICD-10 
Dx
Nicotine dependence, cigarettes, in remission
F17213
ICD-10 
Dx
Nicotine dependence, cigarettes, with withdrawal
F17218
ICD-10 
Dx
Nicotine dependence, cigarettes, with other 
nicotine-induced disorders
F17219
ICD-10 
Dx
Nicotine dependence, cigarettes, with unspecified 
nicotine-induced disorders
F17220
ICD-10 
Dx
Nicotine dependence, chewing tobacco, 
uncomplicated
F17221
ICD-10 
Dx
Nicotine dependence, chewing tobacco, in 
remission
F17223
ICD-10 
Dx
Nicotine dependence, chewing tobacco, with 
withdrawal
F17228
ICD-10 
Dx
Nicotine dependence, chewing tobacco, with other 
nicotine-induced disorders
F17229
ICD-10 
Dx
Nicotine dependence, chewing tobacco, with 
unspecified nicotine-induced disorders

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F17290
ICD-10 
Dx
Nicotine dependence, other tobacco product, 
uncomplicated
F17291
ICD-10 
Dx
Nicotine dependence, other tobacco product, in 
remission
F17293
ICD-10 
Dx
Nicotine dependence, other tobacco product, with 
withdrawal
F17298
ICD-10 
Dx
Nicotine dependence, other tobacco product, with 
other nicotine-induced disorders
F17299
ICD-10 
Dx
Nicotine dependence, other tobacco product, with 
unspecified nicotine-induced disorders
T65211A
ICD-10 
Dx
Toxic effect of chewing tobacco, accidental 
(unintentional), initial encounter
T65211D
ICD-10 
Dx
Toxic effect of chewing tobacco, accidental 
(unintentional), subsequent encounter
T65211S
ICD-10 
Dx
Toxic effect of chewing tobacco, accidental 
(unintentional), sequela
T65214A
ICD-10 
Dx
Toxic effect of chewing tobacco, undetermined, 
initial encounter
T65214D
ICD-10 
Dx
Toxic effect of chewing tobacco, undetermined, 
subsequent encounter
T65214S
ICD-10 
Dx
Toxic effect of chewing tobacco, undetermined, 
sequela
T65221A
ICD-10 
Dx
Toxic effect of tobacco cigarettes, accidental 
(unintentional), initial encounter
T65221D
ICD-10 
Dx
Toxic effect of tobacco cigarettes, accidental 
(unintentional), subsequent encounter
T65221S
ICD-10 
Dx
Toxic effect of tobacco cigarettes, accidental 
(unintentional), sequela
T65224A
ICD-10 
Dx
Toxic effect of tobacco cigarettes, undetermined, 
initial encounter
T65224D
ICD-10 
Dx
Toxic effect of tobacco cigarettes, undetermined, 
subsequent encounter
T65224S
ICD-10 
Dx
Toxic effect of tobacco cigarettes, undetermined, 
sequela
T65291A
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
accidental (unintentional), initial encounter

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T65291D
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
accidental (unintentional), subsequent encounter
T65291S
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
accidental (unintentional), sequela
T65294A
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
undetermined, initial encounter
T65294D
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
undetermined, subsequent encounter
T65294S
ICD-10 
Dx
Toxic effect of other tobacco and nicotine, 
undetermined, sequela
Z716
ICD-10 
Dx
Tobacco abuse counseling
Z720
ICD-10 
Dx
Tobacco use
Z87891
ICD-10 
Dx
Personal history of nicotine dependence
G0436
HCPC
S
Smoking and tobacco cessation counseling visit for 
the asymptomatic patient; intermediate, greater than 
3 minutes, up to 10 minutes
G0437
HCPC
S
Smoking and tobacco cessation counseling visit for 
the asymptomatic patient; intensive, greater than 10 
minutes
G9016
HCPC
S
Smoking cessation counseling, individual, in the 
absence of or in addition to any other evaluation and 
management service, per session (6-10 minutes) 
[demo project code only]
G9276
HCPC
S
Documentation that patient is a current tobacco user
G9458
HCPC
S
Patient documented as tobacco user and received 
tobacco cessation intervention (must include at least 
one of the following: advice given to quit smoking 
or tobacco use, counseling on the benefits of 
quitting smoking or tobacco use, assistance with or 
referral to external smoking or tobacco cessation 
support programs, or current enrollment in smoking 
or tobacco use cessation program) if identified as a 
tobacco user

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G9497
HCPC
S
Received instruction from the anesthesiologist or 
proxy prior to the day of surgery to abstain from 
smoking on the day of surgery
G9642
HCPC
S
Current smokers (e.g., cigarette, cigar, pipe, e-
cigarette or marijuana)
G9644
HCPC
S
Patients who abstained from smoking prior to 
anesthesia on the day of surgery or procedure
G9645
HCPC
S
Patients who did not abstain from smoking prior to 
anesthesia on the day of surgery or procedure
G9792
HCPC
S
Most recent tobacco status is not tobacco free
G9902
HCPC
S
Patient screened for tobacco use and identified as a 
tobacco user
G9906
HCPC
S
Patient identified as a tobacco user received tobacco 
cessation intervention (counseling and/or 
pharmacotherapy)
G9907
HCPC
S
Documentation of medical reason(s) for not 
providing tobacco cessation intervention (e.g., 
limited life expectancy, other medical reason)
G9908
HCPC
S
Patient identified as tobacco user did not receive 
tobacco cessation intervention (counseling and/or 
pharmacotherapy), reason not given
G9909
HCPC
S
Documentation of medical reason(s) for not 
providing tobacco cessation intervention if 
identified as a tobacco user (e.g., limited life 
expectancy, other medical reason)
S4990
HCPC
S
Nicotine patches, legend
S4991
HCPC
S
Nicotine patches, nonlegend
S4995
HCPC
S
Smoking cessation gum
S9453
HCPC
S
Smoking cessation classes, nonphysician provider, 
per session
99406
CPT
Smoking and tobacco use cessation counseling visit; 
intermediate, greater than 3 minutes up to 10 
minutes

BOEHRINGER INGELHEIM Group of Companies
c37262534-01
NIS Protocol
Page 251 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
99407
CPT
Smoking and tobacco use cessation counseling visit; 
intensive, greater than 10 minutes
1032F
CPT
Current tobacco smoker OR currently exposed to 
secondhand smoke (asthma)
1033F
CPT
Current tobacco nonsmoker AND not currently 
exposed to secondhand smoke (Asthma)
1034F
CPT
Current tobacco smoker (CAD, CAP, COPD, PV) 
(DM)
1035F
CPT
Current smokeless tobacco user (eg, chew, snuff) 
(PV)
4000F
CPT
Tobacco use cessation intervention, counseling 
(COPD, CAP, CAD, Asthma)(DM)(PV)
4001F
CPT
Tobacco use cessation intervention, pharmacologic 
therapy (COPD, CAP,CAD, Asthma)(DM)(PV)

BOEHRINGER INGELHEIM Group of Companies
c37262534-01
NIS Protocol
Page 252 of 252
Proprietary confidential information © 2022 Boehringer Ingelheim International GmbH or one or more of its affiliated companies
Stiolto vs Trelegy V1.0 04 May
2021
001-
MCS-90-118_RD-23 (1.0) / Saved on: 25 Nov 2019
ANNEX 4. REVIEWERS AND APPROVAL SIGNATURES
The NIS Protocol must be sent for review to the following individuals prior to approval.
Reviewer
NIS involving BI 
product(s)
NIS not involving BI 
product(s)
Global 
NIS
Local NIS
NIS Lead
X
X
X
Global TM Epi
X
X
X
Global TMM / TMMA / TM 
Market Access
X
X
Global Project Statistician
X
X
Global TM RA
X
Global PVWG Chair
X
GPV SC
X
X
X
Global CTIS representative
X
Local Medical Director
X (if local study)
X
Local Head MAcc / HEOR 
Director
X (if local study)
X
Global TA Head Epi*
X
X
Global TA Head Clinical 
Development / Medical Affairs
/ Market Access*
X
X
Global TA Head PV RM*
X
RWE CoE
X
X
PSTAT / PSTAT-MA                   
(for NISnd only)
X
X
X
NIS DM
X
X
X 
Local Head MA/Clinical 
Development
X (does not apply to 
NISed without chart 
abstraction)
* After review by Global TM for function

 
 
 
 
APPROVAL / SIGNATURE PAGE 
 
Document Number: 
 
Technical Version Number:
 
Document Name: 
 
 
 
                                                                                                                 
 
Title: 
 
 
 
 
                                                                                                                   
 
Signatures (obtained electronically) 
 
Meaning of Signature  
Signed by 
Date Signed 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
c37262534
1.0
nis-us-heor-stiolto-vs-trelegy-study-protocol
Health Care Resource Utilization, Cost and Other Outcomes of Patients Diagnosed
with COPD Initiating Tiotropium Bromide/Olodaterol versus Fluticasone
Furoate/Umeclidinium/Vilanterol
Approval
31 Mar 2022 15:44 CEST
Approval
31 Mar 2022 15:52 CEST
Approval
31 Mar 2022 16:54 CEST

Boehringer Ingelheim 
Page 2 of 2
Document Number: 
 Technical Version Number:
 
 
 
(Continued) Signatures (obtained electronically) 
 
Meaning of Signature  
Signed by 
Date Signed 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
c37262534
1.0