Treatment for Hidradenitis Suppurativa
Conditions: Hidradenitis Suppurativa
Sponsor: The First Affiliated Hospital with Nanjing Medical University

Title page
Title:
Mesalazine in the Treatment of Hidradenitis Suppurativa: a case series
Date：
August 29, 2024
Study Protocol:
We performed clinical, laboratory tests and ultrasound evaluations to confirm HS lesions at
baseline as well as in the follow-up visits. The patients were divided into mild to moderate
group (Hurley stage I, II) and severe group(Hurley stage III) . Their baseline score on the the
IHS4 and DLQI scales before and after starting the treatment were compared. We also
registered the number of patients who achieved HiSCR.
Statistical Analysis Plan:
All the collected data were integrated, and SPSS 26 statistical software was used for data
analysis. After normality test, the measurement data were described by mean ± standard
deviation if they met normal distribution. Those who did not fit were described by median
(upper quartile, lower quartile).
The measurement data were tested for normality, and if they fit normal distribution, analysis
of variance was performed. If the variance is homogeneous, the t test is used, otherwise the
approximate t test is used. If the data does not conform to a normal distribution, the rank sum
test is used. For rank data, ordered regression analysis and independent sample rank sum
test were used. In statistical analysis, a P-value less than 0.05 indicates a statistical difference.
A P-value of less than 0.01 indicates a statistically significant difference.