Unlock the Cell: Intracellular Inflammatory Pathways and Flow Cytometry Study for Castleman's Disease
Conditions: Castleman Disease, Angiofollicular Lymphoid Hyperplasia, GLNH, Hyperplasia, Castleman's Disease, Angiofollicular Lymph Hyperplasia, Giant Lymph Node Hyperplasia
Sponsor: University of Pennsylvania

University of Pennsylvania 
Institutional Review Board 
3800 Spruce St., First Floor Suite 151 
Philadelphia, PA 19104 
Ph: 215-573-2540 
(Federalwide Assurance # 00004028)  
11-Apr-2019 
 
 
Vera Krymskaya 
Attn: Sheila Pierson 
spierson@pennmedicine.upenn.edu 
krymskay@mail.med.upenn.edu 
 
 
PRINCIPAL INVESTIGATOR : Vera Krymskaya 
TITLE 
: Research in Multicentric Castleman Disease 
SPONSORING AGENCY 
: No Sponsor Number 
PROTOCOL # 
: 823546 
REVIEW BOARD 
: IRB #7 
 
Dear Dr. Krymskaya: 
 
The above-referenced protocol received final review on 10-Apr-2019. As instructed, the project was closed. The protocol file will 
be archived according to University policies. 
 
If you have any questions about the information in this letter, please contact the IRB administrative staff. Contact information is 
available at our website: http://www.upenn.edu/IRB/directory. 
 
Thank you for your cooperation.  
 
 
Sincerely, 
 
 
 
 
IRB Administrator  
Renee 
Crews
Digitally signed 
by Renee Crews 
Date: 2019.04.15 
13:55:02 -04'00'