Prospective Evaluation of the Impact on Patients' Quality of Life of a 12-Week Adapted Physical Activity Program (APA) at Institut de Cancerologie de l'Ouest (ICO)
Conditions: Sports Physical Therapy
Sponsor: Institut Cancerologie de l'Ouest

Short Title: APA 
Ref ICO:  ICO-2020-05 
ID-RCB: 2020-A00275-34 
 
 
 
Synopsis APA _ English translated from initial authorized French version V1 dated 06.02.2020 
 
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SYNOPSIS 
 
SHORT TITLE / OFFICIAL TITLE 
APA 
Prospective Evaluation of the Impact on Patients' Quality of Life of a 12-Week 
Adapted Physical Activity Program (APA) at Institut de Cancerologie de l'Ouest 
(ICO) 
SPONSOR 
Institut de Cancerologie de l'Ouest (ICO) 
INVESTIGATOR COORDINATOR 
Dr Sophie ABADIE-LACOURTOISIE 
Oncologue Médical 
METHODOLOGIST / STATISTICIAN 
Dr Valérie SEEGERS And Catherine GUERIN-CHARBONNEL 
Institut de Cancérologie de l’Ouest 
Direction de la Recherche Clinique (DRC) 
OBJECTIVES 
Primary: 
Describe the changes in quality of life experienced by cancer patients treated at 
the ICO site in Angers who participated in the ICO's 12-week adapted physical 
activity program. 
 
Secondary: 
a) Describe attendance at the APA program. 
b) Measure changes in kinesiophobia. 
c) Measure physical activity at the start of the APA program. 
METHODOLOGY 
This is a prospective, non-comparative, monocenter cohort study with the 
administration of a quality-of-life questionnaire. 
TARGET POPULATION 
Adult subjects enrolled in the APA program at ICO (Angers site) during the first 
semester of 2020, regardless of cancer type and ongoing treatment 
(chemotherapy, radiotherapy, hormone therapy, immunotherapy). 
NUMBER OF PATIENTS 
All patients meeting the eligibility criteria. 
About 70 patients.  
NUMBER OF CENTRES  
1 – ICO Site Angers 
STATISTICAL ANALYSIS 
This is a descriptive study aiming to characterize the quality of life of cancer 
patients during their APA program. A flowchart will be created to define the 
completion rate of questionnaires at different time points. 
Baseline characteristics of the population will be described. Quantitative data will 
be summarized using mean, standard deviation, median, minimum, maximum, 
and 25th and 75th percentiles. Categorical or binary data will be summarized by 
distribution across categories and expressed as percentages. The number of 
missing data will be reported. No imputation procedure for missing data is 
planned. 
Individual trajectories of FACIT scores will be graphically presented with sample 
sizes clearly indicated at each time point. Scores (quantitative data) will be 
summarized at the three measurement times. A paired data comparison will be 
performed to compare scores across time points. 
TAMPA scores (quantitative data) will be graphically presented using boxplots.