The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive Protein Levels in Overweight Women
Phase: NA
Conditions: Overweight, Obesity, Inflammation, Low-Grade, Cardiovascular Diseases, Risk Factors
Sponsor: Xianjie Zheng

Official Title: The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity
C-Reactive Protein Levels in Overweight Women
NCT Number: NCT number pending
Document Type: Study Protocol with Statistical Analysis Plan
Document Date: January 15, 2024
Sponsor/Institution: College of Physical Education and Health, Chongqing College of
International Business and Economics, Hechuan, Chongqing, China
Study Protocol Overview
This document describes the full study protocol and statistical analysis plan for the research titled
“The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive
Protein Levels in Overweight Women.” The study was approved by the Research Ethics Committee
of Chongqing College of International Business and Economics (Approval No. K2016038) on
January 15, 2024. It was conducted between January 20, 2024, and April 10, 2024, with 22
overweight female participants randomly assigned to either an exercise or a control group. The
exercise intervention consisted of an eight-week circuit-based combined training program
performed four times per week at 70–90% of maximum heart rate. Measurements included serum
adiponectin and hs-CRP concentrations (ELISA), as well as body composition and VOImax
assessments at baseline and 48 hours post-intervention. Statistical analysis included paired t-tests
for within-group changes, ANCOVA for between-group comparisons, and Pearson correlation for
associations between biomarkers. Significance was determined at P < 0.05 using SPSS version 17.