I want to know the answer to the following question:
What causes the directionality of DNA strands?
All the background I'm provided with is that "Nucleic acid synthesis, including DNA replication and transcription occurs in the 5'→3' direction, because new nucleotides are added via a dehydration reaction that uses the exposed 3' hydroxyl as a nucleophile.:27.2". Is that enough to answer the question?
Answer: no