I want to know the answer to the following question:
What historical period gave the Dominican Order a challenge?
All the background I'm provided with is that "It struggled against pagan tendencies in Renaissance humanism, in Italy through Dominici and Savonarola, in Germany through the theologians of Cologne but it also furnished humanism with such advanced writers as Francesco Colonna (probably the writer of the Hypnerotomachia Poliphili) and Matteo Bandello.". Is that enough to answer the question?
Answer: no