Jerryhuang001/TF_network huggingface dataset:
Gene: ZNF320 (ENSG00000182986)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Jussi Taipale) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF322 (ENSG00000181315)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF324 (ENSG00000083812)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Tim Hughes) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF324B (ENSG00000249471)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: In vivo/Misc source
Notes: Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Yimeng Yin) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF326 (ENSG00000162664)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Comments: ZNF326 is a member of the DBIRD complex that regulates splicing by binding to PolII in an RNA-independant manner (PMID:22446626).
Disagreement on assessment: Disagree
Disagreement on binding: Disagree
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: ZNF326 is a member of the DBIRD complex that regulates splicing by binding to PolII in an RNA-independant manner (PMID:22446626); with no evidence of DNA-binding activity. Labeled as Class 4 based on it's homologue AKAP8 having non-specific DNA-bindi
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: Indeterminate - There is no evidence for or against this genes role as a TF__DNA Binding_PMIDS:9809746;10798446
Annotated as a GO transcription factor: No
Gene: ZNF329 (ENSG00000181894)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF331 (ENSG00000130844)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Tim Hughes) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Jussi Taipale) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 comment: ChIP-seq only
Reviewer 2 notes: C2H2; check for amino-acids required for DNA binding
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF333 (ENSG00000160961)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Disagreement on assessment: Disagree
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Yimeng Yin) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF334 (ENSG00000198185)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: In vivo/Misc source
Notes: Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF335 (ENSG00000198026)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Notes: Has a putative AT-hook
Reviewer 1 (Laura Campitelli) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF337 (ENSG00000130684)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Tim Hughes) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF33A (ENSG00000189180)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF33B (ENSG00000196693)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Yimeng Yin) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF34 (ENSG00000196378)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: In vivo/Misc source
Notes: Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect
Reviewer 1 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Yimeng Yin) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF341 (ENSG00000131061)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: In vivo/Misc source
Notes: Motif obtained from MEME - not supported by recognition code (RCADE) and may be inaccurate or indirect
Reviewer 1 (Jussi Taipale) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF343 (ENSG00000088876)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Reviewer 1 (Jussi Taipale) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF345 (ENSG00000251247)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Reviewer 1 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF346 (ENSG00000113761)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Comments: Binds dsDNA with low affinity and no discernible specificity (PMID: 24521053).
Disagreement on assessment: Disagree
Reviewer 1 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Binds dsDNA with low affinity and no discernible specificity (PMID: 24521053)
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF347 (ENSG00000197937)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF35 (ENSG00000169981)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Disagreement on assessment: Disagree
Reviewer 1 (Jussi Taipale) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF350 (ENSG00000256683)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF354A (ENSG00000169131)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: TF Gene_DNA-Binding: non-sequence-specific_Transactivation_PMIDS:8183940;9346939
Annotated as a GO transcription factor: Yes
Gene: ZNF354B (ENSG00000178338)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Disagreement on assessment: Disagree
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF354C (ENSG00000177932)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: In vivo/Misc source
Reviewer 1 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Trono motif is unavailable 
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF355P (ENSG00000168122)
DNA-binding domain: C2H2 ZF
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Notes: Pseudogene
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: pseudogene
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: It is putative zinc finger; UniProtKB - Q9NSJ1
CisBP considers it a TF: No
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF358 (ENSG00000198816)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Sam Lambert) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF362 (ENSG00000160094)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Comments: Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains
Reviewer 1 (Arttu Jolma) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Virtually nothing is known for this protein except that it has a decent cassette of znfC2H2 domains
Reviewer 2 (Yimeng Yin) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF365 (ENSG00000138311)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Notes: Single C2H2 domain
Comments: Also contains a Ku C terminal like domain that is thought to be involved in DNA-damage repair pathways.
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: None of the transcripts appear to have putative DBDs
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Zinc-finger domain annotation seems to be false; Uniprot and Ensembl database lack predictions of ZF modules. Also contains a Ku C terminal like domain that is thought to be involved in DNA-damage repair pathways.
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF366 (ENSG00000178175)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Comments: This protein has been shown to complex with and function as a corepressor for ESR1 (PMID: 17085477) and glucocorticoid receptor (PMID: 23440419). It has a nice set of znfs and could thus well bind DNA independently.
Reviewer 1 (Arttu Jolma) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: This protein has been shown to complex with and function as a corepressor for ESR1 PMID: 17085477 and glucocorticoid receptor PMID: 23440419. It has a nice set of znfs and could thus well bind DNA independently
Reviewer 2 (Pratyush Das) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF367 (ENSG00000165244)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Notes: Has a putative AT-hook
Comments: Virtually nothing is known for this protein except that it has two znfC2H2 domains next to each other
Reviewer 1 (Arttu Jolma) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Virtually nothing is known for this protein except that it has two znfC2H2 domains next to each other
Reviewer 2 (Sam Lambert) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 2 comment: GO annotation has no evidence for DNA-binding activity (PMID:15344908); only transcriptional activation in reporter experiments 
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF37A (ENSG00000075407)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Disagreement on assessment: Disagree
Reviewer 1 (Tim Hughes) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 2 notes: check for residues required for DNA binding
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF382 (ENSG00000161298)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Reviewer 1 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Some discrepancy between motifs 
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF383 (ENSG00000188283)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Notes: ChIP-seq motif is consistent with recognition code (RCADE)
Disagreement on assessment: Disagree
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 comment: ChIP-seq only
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: ZNF384 (ENSG00000126746)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 1 Monomer or homomultimer
Motif status: High-throughput in vitro
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 1 comment: Accepts also other homodimeric spacing and orientations combinations besides the one chosen for the Yin et al paper
Reviewer 2 (Sam Lambert) assessment: Has known motif; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF385A (ENSG00000161642)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Laura Campitelli) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: ZNF385B (ENSG00000144331)
DNA-binding domain: C2H2 ZF
Is a transcription factor: Yes
TF assessment: Likely to be sequence specific TF
Binding mode: 1 Monomer or homomultimer
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 1 notes: C2H2; check for amino-acids required for DNA binding
Reviewer 2 (Sam Lambert) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No