Jerryhuang001/TF_network huggingface dataset:
Gene: HIRA (ENSG00000100084)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Notes: Has a putative AT-hook
Comments: Histone chaperone - TUP1 homolog.
Committee notes: Histone chaperone - TUP1 homolog.
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 notes: chromatin modifier; many of these contain AT hooks or other low specificity DBDs
Reviewer 2 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: HIST1H1A (ENSG00000124610)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Histone component
Reviewer 1 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Histone component
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HIST1H1B (ENSG00000184357)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Linker histone.  To my knowledge there has been no demonstration of sequence specificity of linker histones, so I think this one should be called "unlikely". 
Committee notes: Linker histone.  To my knowledge there has been no demonstration of sequence specificity of linker histones, so I think this one should be called "unlikely".  I will be happy to change my assessment if new information is presented.
Disagreement on assessment: Disagree
Reviewer 1 (Jussi Taipale) assessment: Likely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HIST1H1C (ENSG00000187837)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HIST1H1D (ENSG00000124575)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Linker histone that binds DNA as heteromeric complex with the other histone proteins
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Linker histone that binds DNA as heteromeric complex with the other histone proteins
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Histone component
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HIST1H1E (ENSG00000168298)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA as heteromultimeric complex 
Disagreement on binding: Disagree
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA as heteromultimeric complex 
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HIST1H1T (ENSG00000187475)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HLA-DQB1 (ENSG00000179344)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HLA-DQB2 (ENSG00000232629)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
TFclass considers it a TF: No
Gene: HLA-DRB1 (ENSG00000196126)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HLA-DRB3 (ENSG00000196101)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 notes: annotation missing
Reviewer 2 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
TFclass considers it a TF: No
Gene: HLA-DRB5 (ENSG00000198502)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HLTF (ENSG00000071794)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: In vivo/Misc source
Notes: Only known motifs are from Transfac or HocoMoco - origin is uncertain
Comments: DNA repair protein. Even though it has 3 motifs, there is no compelling evidence that it really binds dsDNA - only single stranded DNA
Disagreement on binding: Disagree
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Even though it has 3 motifs; I cant find compelling evidence that it really binds DNA - only single stranded DNA
Reviewer 1 notes: Yes - it does have 3 motifs; but they all look fishy.
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Early gel-shift experiments (PMID: 9427542) suggest that HLTF has sequence specific DNA-binding activity. However; more recent structural and functional evidence suggests that HLTF is instead involved in replication fork reversal and binds both ss- a
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: TF Gene Candidate_Transcription Regulatory Activity: heterochromatin interaction/binding_DNA Binding_PMIDS:9427542
Annotated as a GO transcription factor: No
PDB structure: 4S0N
Gene: HMOX1 (ENSG00000100292)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Well characterized enzyme with no additional domains.  Included only because GO lists it as a regulator of TFs.  No support for DNA binding activity.
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Well characterized enzyme with no additional domains.  Included only because GO lists it as a regulator of TFs.  No support for DNA binding activity.
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: HNRNPA1 (ENSG00000135486)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Binds single stranded DNA in the structure (PDB: 1PGZ)
TRH notes: heterogeneous nuclear ribonucleoprotein A1 
AJ notes: 1PGZ
Reviewer 1 (Arttu Jolma) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Binds single stranded DNA in the structure; PDB: 1PGZ
Reviewer 2 (Sam Lambert) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
TFclass considers it a TF: No
Gene: HNRNPA3 (ENSG00000170144)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Protein is a well established RBP
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Protein is a well established RBP
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Likely an RNA-binding protein 
Reviewer 2 notes: Wrong entrez summary 
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Evidence Conflict - There is evidence for and against this genes role as a TF_Transcription Factor Binding: tf co-factor binding__PMIDS:0
Annotated as a GO transcription factor: No
Gene: HNRNPAB (ENSG00000197451)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: HNRNPAB proteins are involved in pre-mRNA splicing. However; RRM domains can also constitute ssDNA binding domains
Disagreement on binding: Disagree
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: HNRNPAB proteins are involved in pre-mRNA splicing. However; RRM domains can also constitute ssDNA binding domains
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Couldnt find evidence for its DNA binding however PMID: 7876260 says hnRNP K can bind DNA
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: HNRNPCL2 (ENSG00000275774)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Protein is a well established RBP
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: RBP?
Reviewer 2 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Protein is a RNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Evidence Conflict - There is evidence for and against this genes role as a TF_Transcription Factor Binding: tf co-factor binding; DNA-Binding: sequence-specific_Other_PMIDS:16010978;16217013
Annotated as a GO transcription factor: No
Gene: HNRNPD (ENSG00000138668)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Binds single stranded DNA in the structure (PDB: 1WTB)
TRH notes: heterogeneous nuclear ribonucleoprotein D 
AJ notes: 1WTB
Reviewer 1 (Arttu Jolma) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Binds single stranded DNA in the structure; PDB: 1WTB
Reviewer 2 (Sam Lambert) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
TFclass considers it a TF: No
Gene: HNRNPDL (ENSG00000152795)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Protein is a well established RBP
Reviewer 1 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds ssDNA
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: PMID: 9538234 says it binds to ds DNA; ss DNA; Poly(G); Poly(A).
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene Candidate_Single stranded RNA/DNA binding_Non-specific DNA_PMIDS:9538234
Annotated as a GO transcription factor: No
Gene: HNRNPK (ENSG00000165119)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Protein is a well established RBP
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: RBP?
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Single stranded RNA/DNA binding_Co-activation; DNA Binding; TF PPI; Transactivation_PMIDS:8628302;8650178
Annotated as a GO transcription factor: Yes
PDB structure: 1J5K
Gene: HNRNPL (ENSG00000104824)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: HNRNPL is a well-established RNA-binding protein; and the DNA-binding evidence was neither shown to be specific or direct (PMID: 11809897) 
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: HNRNPL is a well-established RNA-binding protein; and the DNA-binding evidence was neither shown to be specific or direct (PMID:11809897) 
Reviewer 1 notes: Missing domain logos 
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Splicing factor
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Evidence Conflict - There is evidence for and against this genes role as a TF_Transcription Factor Binding: tf co-factor binding_Co-activation_PMIDS:11809897
Annotated as a GO transcription factor: No
Gene: HNRNPU (ENSG00000153187)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Binds pre-mRNA in vivo and binds both RNA and ssDNA in vitro (PMID: 1628625)
Reviewer 1 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds pre-mRNA in vivo and binds both RNA and ssDNA in vitro [PMID: 1628625]
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: It binds RNA; pubmed 1628625
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene Candidate_Transcription Factor Binding: tf co-factor binding_TF PPI; Transactivation_PMIDS:9353307;15096513
Annotated as a GO transcription factor: No
Gene: HP1BP3 (ENSG00000127483)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Histone H1-like protein.  Binds in ChIP experiments (PMID: 27425409) and binds DNA (likely non-specifically) with HP1.
Committee notes: Histone H1-like protein.  ChIPs (PMID: 27425409) and binds DNA (possibly non-specifically) with HP1.  I think this should be treated like other linker histones as there is no evidence for sequence specificity.
Disagreement on binding: Disagree
Reviewer 1 (Matt Weirauch) assessment: Likely to be sequence specific TF; binding: 1 Monomer or homomultimer
Reviewer 2 (Pratyush Das) assessment: Likely to be sequence specific TF; binding: 2 Obligate heteromer
Reviewer 2 comment: PMID: 27425409; PMID: 20042602 says that it binds DNA 
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: HR (ENSG00000168453)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: JmjC domain is not a DBD, and GO annotation is based on homology to a zinc finger motif and not experimental DNA-binding evidence (PMID: 9445480)
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: JmjC domain is not a DBD; and GO annotation is based on homology to a zinc finger motif and not experimental DNA-binding evidence (PMID:9445480)
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: HSBP1 (ENSG00000230989)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Protein that has been shown to bind to HSF1 leading to inhibition of its trimerization and DNA-binding( PMID: 9649501).
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Protein that has been shown to bind to HSF1 leading to inhibition of its trimerization and DNA-binding PMID: 9649501. Although it could possibly bind to different sites as heterodimeric complex with this protein?
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: Indeterminate - There is no evidence for or against this genes role as a TF__Transactivation_PMIDS:12038984
Annotated as a GO transcription factor: No
Gene: HSPA1A (ENSG00000204389)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: HSPA1B (ENSG00000204388)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
TFclass considers it a TF: No
Gene: ICAM1 (ENSG00000090339)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: IFI16 (ENSG00000163565)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Recognizes DNA without sequence specificity (PMID: 22618232; PMID: 18472023)
Disagreement on binding: Disagree
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Recognizes DNA without sequence specificity: PMID 22618232; 18472023
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
PDB structure: 3RNU
Gene: IFNB1 (ENSG00000171855)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: IGHM (ENSG00000211899)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No