Jerryhuang001/TF_network huggingface dataset:
Gene: PNKP (ENSG00000039650)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 3ZVN)
TRH notes: polynucleotide kinase 3'-phosphatase 
AJ notes: 3ZVN
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 3ZVN
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
TFclass considers it a TF: No
Gene: POGZ (ENSG00000143442)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Has a potential DBD that is similar to Drosophila Brinker but no other data suggesting TF function.  Likely co-factor.
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Has a potential DBD that is similar to Drosophila Brinker but no other data suggesting TF function
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: POGZ contains multiple domains with putative (HTH) and likely non-specific (DDE) DNA-binding activity. Given that POGZ has been shown to interact with transcriptionally related proteins like Sp1 (PMID:10976766); and Heterochromatin protein 1 (HP1;  P
CisBP considers it a TF: No
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: POLA1 (ENSG00000101868)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 4Q5V)
TRH notes: polymerase (DNA) alpha 1, catalytic subunit 
AJ notes: 4Q5V
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 4Q5V
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
TFclass considers it a TF: No
Gene: POLB (ENSG00000070501)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase that participates in base excision repair. Binds DNA in the crystal structure (PDB: 1BPX)
TRH notes: polymerase (DNA) beta 
AJ notes: 1BPX
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase that participates in base excision repair; Binds DNA in the crystal structure; PDB: 1BPX
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
TFclass considers it a TF: No
Gene: POLE3 (ENSG00000148229)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: POLE4 (ENSG00000115350)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Histone-like subunit of DNA polymerase epsilon
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: histone-like subunit of DNA polymerase epsilon
Reviewer 2 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: See the Entrez summary
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: POLG (ENSG00000140521)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 4ZTU)
TRH notes: polymerase (DNA) gamma, catalytic subunit 
AJ notes: 4ZTU
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 4ZTU
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Mitochondrial polymerase
TFclass considers it a TF: No
Gene: POLH (ENSG00000170734)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase. Binds DNA in the crystal structure (PDB: 3JAA)
TRH notes: polymerase (DNA) eta 
AJ notes: 3JAA
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase; Binds DNA in the crystal structure; PDB: 3JAA
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Involved in DNA repair
TFclass considers it a TF: No
Gene: POLI (ENSG00000101751)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase. Binds DNA in the crystal structure (PDB: 1T3N)
TRH notes: polymerase (DNA) iota 
AJ notes: 1T3N
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase; Binds DNA in the crystal structure; PDB: 1T3N
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Involved in DNA repair
TFclass considers it a TF: No
Gene: POLK (ENSG00000122008)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase. Binds DNA in the crystal structure (PDB: 2OH2)
TRH notes: polymerase (DNA) kappa 
AJ notes: 2OH2
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase; Binds DNA in the crystal structure; PDB: 2OH2
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Involved in DNA repair
TFclass considers it a TF: No
Gene: POLL (ENSG00000166169)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase. Binds DNA in the crystal structure (PDB: 1RZT)
TRH notes: polymerase (DNA) lambda 
AJ notes: 1RZT
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase; Binds DNA in the crystal structure; PDB: 1RZT
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Involved in DNA repair
TFclass considers it a TF: No
Gene: POLM (ENSG00000122678)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: DNA polymerase that operates on non-homologous end joining. Binds DNA in the crystal structure (PDB: 2IHM)
TRH notes: polymerase (DNA) mu 
AJ notes: 2IHM
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: DNA polymerase that operates on non-homologous end joining ;Binds DNA in the crystal structure; PDB: 2IHM
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Gap filling polymerase
TFclass considers it a TF: No
Gene: POLN (ENSG00000130997)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 4XVI)
TRH notes: polymerase (DNA) nu 
AJ notes: 4XVI
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 4XVI
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Low-fildelity DNA polymerase
TFclass considers it a TF: No
Gene: POLQ (ENSG00000051341)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 4X0P)
TRH notes: polymerase (DNA) theta 
AJ notes: 4X0P
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 4X0P
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: Involved in error-prone DNA-repair
TFclass considers it a TF: No
Gene: POLR1B (ENSG00000125630)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: General Transcription Factor 
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: General Transcription Factor 
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Basal Transcription Factor__PMIDS:0
Annotated as a GO transcription factor: No
Gene: POLR2A (ENSG00000181222)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Contacts DNA in the structure (PDB: 5FLM)
Disagreement on assessment: Disagree
Reviewer 1 (Sam Lambert) assessment: Likely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Basal TF; structural evidence shows base contacts (PDB:5FLM)
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Basal Transcription Factor_DNA Binding; TF PPI_PMIDS:8870495
Annotated as a GO transcription factor: No
PDB structure: 5FLM
Gene: POLR2B (ENSG00000047315)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Contacts DNA in the structure (PDB: 5FLM)
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Subunit of RNA Pol II
Reviewer 1 notes: Subunit of RNA Pol II. Perhaps our categorization scheme needs to separate nonspecific and low specificity DNA binding proteins?
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_DNA-Binding: non-sequence-specific; Basal Transcription Factor; Transcription Factor Binding: tf co-factor binding_DNA Binding; Non-specific DNA; TF PPI_PMIDS:10784442
Annotated as a GO transcription factor: No
PDB structure: 5FLM
Gene: POLR2E (ENSG00000099817)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: RNA-polymerase subunit. Binds DNA in the crystal structure (PDB: 5IY6)
TRH notes: polymerase (RNA) II subunit E 
AJ notes: 5IY6
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: RNA-polymerase subunit. ;Binds DNA in the crystal structure; PDB: 5IY6
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
TFclass considers it a TF: No
Gene: POLR2J (ENSG00000005075)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Does not contact DNA in the structure (PDB: 5FLM)
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Binds DNA non-specifically as a heteromultimeric complex
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Basal Transcription Factor__PMIDS:0
Annotated as a GO transcription factor: No
PDB structure: 5FLM
Gene: POLR2K (ENSG00000147669)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Does not contact DNA in the structure (PDB: 5FLM)
Disagreement on binding: Disagree
Reviewer 1 (Jussi Taipale) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: UniProtKB - P53803 it may bind DNA
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene Candidate_Transcription Factor Binding: tf co-factor binding_DNA Binding; Transactivation_PMIDS:7651387
Annotated as a GO transcription factor: No
PDB structure: 5FLM
Gene: POLR2L (ENSG00000177700)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Does not contact DNA in the structure (PDB: 5FLM)
Disagreement on binding: Disagree
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: POLR2L (RBP10) doesn't make any contacts with DNA based on a published structure (PDB:5FLM; PMID:26789250 )
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 2 comment: PMID: 8786124 says it has zinc binding domain
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
PDB structure: 5FLM
Gene: POLR3A (ENSG00000148606)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Transfac motifs are dubious, and do not appear to be similar to any known motifs. 
Disagreement on binding: Disagree
Reviewer 1 (Sam Lambert) assessment: Has known motif; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Transfac motifs are dubious; and do not appear similar to any known motifs. 
Reviewer 2 (Pratyush Das) assessment: Has known motif; binding: 1 Monomer or homomultimer
Reviewer 2 comment: Also may put likely TF
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: POLRMT (ENSG00000099821)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 3 Low specificity DNA-binding protein
Motif status: No motif
Comments: Binds DNA in the crystal structure (PDB: 4BOC)
TRH notes: polymerase (RNA) mitochondrial 
AJ notes: 4BOC
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
Reviewer 1 comment: Binds DNA in the crystal structure; PDB: 4BOC
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 3 Low specificity DNA-binding protein
TFclass considers it a TF: No
Gene: POT1 (ENSG00000128513)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Binds single stranded DNA in the structure (PDB: 1XJV)
TRH notes: protection of telomeres 1 
AJ notes: 1XJV
Reviewer 1 (Arttu Jolma) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Binds single stranded DNA in the structure; PDB: 1XJV
Reviewer 2 (Sam Lambert) assessment: ssDNA/RNA binding; binding: 4 Not a DNA binding protein
Reviewer 2 comment: Binds ssDNA at telomeres (PDB:1XJV, PMID:15558049)
TFclass considers it a TF: No
Gene: POU2AF1 (ENSG00000110777)
DNA-binding domain: Unknown
Is a transcription factor: Yes
TF assessment: Known motif
Binding mode: 2 Obligate heteromer
Motif status: In vivo/Misc source
Notes: Only known motifs are from Transfac or HocoMoco - origin is uncertain
Comments: Requires POU2F1 to bind DNA. In the crystal structure (PDB:1CQT), POU2AF1 contacts both the POU2F1 and DNA major groove
MTW notes: Requires POU2F1 to bind DNA; in the crystal structure PDB:1CQT, POU2AF1 contacts both  POU2F1 and the DNA major groove
Reviewer 1 (Arttu Jolma) assessment: Has known motif; binding: 2 Obligate heteromer
Reviewer 1 comment: Requires POU2F1 to bind DNA; in the crystal structure PDB:1CQT the POU2AF1 contacts both the POU2F1 and DNA major groove
Reviewer 2 (Laura Campitelli) assessment: Has known motif; binding: 2 Obligate heteromer
CisBP considers it a TF: Yes
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Transcription Factor Binding: tf co-factor binding_Co-activation; TF PPI_PMIDS:7623806;7779176
Annotated as a GO transcription factor: No
PDB structure: 1CQT
Gene: PPARGC1A (ENSG00000109819)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: PPARGC1B (ENSG00000155846)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Contains a single RRM domain, so could possibly be an RNA binding protein
Reviewer 1 (Arttu Jolma) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Transcriptional co-regulator
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene_Transcription Factor Binding: tf co-factor binding_Co-activation_PMIDS:11854298
Annotated as a GO transcription factor: Yes
Gene: PPP1R13L (ENSG00000104881)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: Yes
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: PPP2R3B (ENSG00000167393)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: No
Gene: PPP2R5B (ENSG00000068971)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: GO cites "inferred from electronic annotation".  Needs to be corrected.
Reviewer 2 (Laura Campitelli) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: PPP3CA (ENSG00000138814)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Matt Weirauch) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Sam Lambert) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: PPRC1 (ENSG00000148840)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: ssDNA/RNA binding
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Reviewer 1 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 2 (Pratyush Das) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: No
Annotated as a GO transcription factor: Yes
Gene: PQBP1 (ENSG00000102103)
DNA-binding domain: Unknown
Is a transcription factor: No
TF assessment: Unlikely to be sequence specific TF
Binding mode: 4 Not a DNA binding protein
Motif status: No motif
Comments: Has a WW domain. May interact with Pol II, but no indication of sequence specific DNA binding
Reviewer 1 (Tim Hughes) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
Reviewer 1 comment: Has a WW domain - may interact with Pol II - but no indication of sequence specific DNA binding
Reviewer 2 (Yimeng Yin) assessment: Unlikely to be sequence specific TF; binding: 4 Not a DNA binding protein
CisBP considers it a TF: No
TFclass considers it a TF: No
TF-CAT classification: TF Gene Candidate_Transcription Factor Binding: tf co-factor binding_TF PPI_PMIDS:10332029
Annotated as a GO transcription factor: No